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all 2322 "C" titles

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  • 2007 ProQuest Safari
    Joseph Albahari and Ben Albahari.
  • 2006 ProQuest Safari
    Jeff Cogswell, Christopher Diggins, Ryan Stephens, Jonathan Turkanis.
    Building C++ applications -- Code organization -- Numbers -- Strings and text -- Dates and times -- Managing data with containers -- Algorithms -- Classes -- Exceptions and safety -- Streams and files -- Science and mathematics -- Multithreading -- Internationalization -- XML -- Miscellaneous.
  • 2006 ProQuest Safari
    Jay Hilyard, Stephen Teilhet.
  • 2015 Springer Protocols
    edited by David Biron, Gal Haspel.
    Library construction for mutation identification by whole-genome sequencing / Harold E. Smith -- Fundamentals of comparative genome analysis in caenorhabditis nematodes / Eric S. Haag and Cristel G. Thomas -- Genetic methods for cellular manipulations in C. elegans / Menachem Katz -- Fusion PCR method for expressing genetic tools in C. elegans / Yifat Eliezer and Alon Zaslaver -- Transposon-assisted genetic engineering with Mos1- mediated single-copy insertion (MosSCI) / Christian Frøkjær-Jensen -- Creating genome modifications in C. elegans using the CRISPR/Cas9 system / John A. Calarco and Ari E. Friedland -- Observing and quantifying fluorescent reporters / Michael Hendricks -- Microbial rhodopsin optogenetic tools : application for analyses of synaptic transmission and of neuronal network activity in behavior / Caspar Glock, Jatin Nagpal, and Alexander Gottschalk -- Simultaneous optogenetic stimulation of individual pharyngeal neurons and monitoring of feeding behavior in intact C. elegans / Nicholas F. Trojanowski and Christopher Fang-Yen -- High-pressure freeze and freeze substitution electron microscopy in C. elegans / Laura Manning and Janet Richmond -- Electron tomography methods for C. elegans / David H. Hall and William J. Rice -- Microfluidic devices for behavioral analysis, microscopy, and neuronal imaging in Caenorhabditis elegans / Ross C. Lagoy and Dirk R. Albrecht -- Tracking single C. elegans using a USB microscope on a motorized stage / Eviatar I. Yemini and André E. X. Brown -- Imaging system for C. elegans behavior / Matthew A. Churgin and Christopher Fang-Yen -- Method for obtaining large populations of synchronized Caenorhabditis elegans dauer larvae / Maria C. Ow and Sarah E. Hall -- Sampling and isolation of C. elegans from the natural habitat / Nausicaa Poullet and Christian Braendle -- Primer on prototyping / Dylan Lynch and David Biron -- Primer on quantitative modeling / Iulia Neagu and Erel Levine.
  • 2006 Springer Protocols
    edited by Kevin Strange.
    An overview of C. elegans biology / Kevin Strange -- Comparative genomics in C. elegans, C. briggsae, and other Caenorhabditis species / Avril Coghlan, Jason E. Stajich, and Todd W. Harris -- WormBase: methods for data mining and coparative genomics / Todd W. Harris and Lincoln D. Stein -- C. elegans deletion mutant screening / Robert J. Barstead and Donald G. Moerman -- Insertional mutagenesis in C. elegans using the drosophila transposon Mos1: a method for the rapid identification of mutated genes / Jean-Louis Bessereau -- Single nucleotide polymorphism mapping / M. Wayne Davis and Marc Hammarlund -- Creation of transgenic lines using microparticle bombardment methods / Vida Praitis -- Construction of plasmids for RNA interference and in vitro transcription of double-stranded RNA / Lisa Timmons -- Delivery methods for RNA interference in C. elegans / Lisa Timmons -- Functional genomic approaches in C. elegans / Todd Lamitina -- Assays for toxicity studies in C. elegans with Bt crystal proteins / Larry J. Bischof, Danielle L. Huffman, and Raffi V. Aroian -- Fluorescent reporter methods / Harald Hutter -- Electrophysiological analysis of neuronal and muscle function in C. elegans / Michael M. Francis and Andres Villu Maricq -- Sperm and oocyte isolation methods for biochemical and proteomic analysis / Michael A. Miller -- Preservation of C. elegans tissue via high-pressure freezing and freeze-substitution for ultrastructural analysis and immunocytochemistry / Robby M. Weimer -- Intracellular pH measurements in vivo using green fluorescent protein variants / Keith Nehrke -- Automated imaging of C. elegans behavior / Christopher J. Cronin, Zhaoyang Feng, and William R. Schafer -- Intracellular Ca2+ imaging in C. elegans / Rex A. Kerr and William R. Schafer -- In vitro culture of C. elegans somatic cells / Kevin Strange and Rebecca Morrison -- Techniques for analysis, sorting, and dispensing of C. elegans on the COPAS flow-sorting system / Rock Pulak.
  • P.J. Deitel, H.M. Deitel.
  • 2006 Springer
    Giovanni Mantovani (ed.) ; co-editors, Stefan D. Anker ... [et al.].
  • 2012 ScienceDirect
    edited by Joel H. Rothman, Andrew Singson.
    An updated edition of the classic Methods in Cell Biology volume 48, this book emphasizes diverse methods and technologies needed to investigate C. elegans, both as an integrated organism and as a model system for research inquiries in cell, developmental, and molecular biology, as well as in genetics and pharmacology. By directing its audience to tried-and-true and cutting-edge recipes for research, this comprehensive collection is intended to guide investigators of C. elegans for years to come.
  • 2011 ScienceDirect
    edited by Joel H. Rothman, Andrew Singson.
    Pt.I Genetics and functional genomics : Mapping mutations in C. elegans / Eric J. Lambie -- Specialized chromosomes and their uses in caenorhabditis elegans / Martin R. Jones, Zoe Lohn, Ann M. Rose -- Genome engineering by transgene-instructed gene conversion in C. elegans / Valérie J.P. Robert, Jean-Louis Bessereau -- RNAi methods and screening : RNAi based high-throughput genetic interaction screening / Patricia G. Cipriani, Fabio Piano -- Dissection of genetic pathways in C. elegans / Zheng Wang, David R. Sherwood -- Pt.II Molecular biology and biochemistry : Transgenesis in C. elegans / Vida Praitis, Morris F. Maduro -- RNA processing in C. elegans / J. Jason Morton, Thomas Blumenthal -- Analysis of microRNA expression and function / Priscilla M. Van Wynsberghe, Shih-Peng Chan, Frank J. Slack, Amy E. Pasquinelli -- In situ hybridization of embryos with antisense RNA probes / Gina Broitman-Maduro, Morris F. Maduro -- Gene-centered regulatory network mapping / Albertha J.M. Walhout -- Affinity purification of protein complexes in C. elegans / Esther Zanin, Julien Dumont, RetoGassmann, Iain Cheeseman, Paul Maddox, Shirin Bahmanyar, Ana Carvalho, Sherry Niessen, John R. Yates III, Karen Oegema, Arshad Desai -- Pt.III Development : Cell indentification and cell lineage analysis / Claudiu A. Giurumescu, Andrew D. Chisholm -- The genetics and cell biology of fertilization / Brian D. Geldziler, Mathew R. Marcello, Diane C. Shakes, Andrew Singson -- Imaging embryonic morphogenesis in C. elegans / Jeff Hardin -- Molecular and genetic approaches for the analysis of C. elegans neuronal development / Dong Yan, Yishi Jin -- Methods for evaluating the caenorhabditis elegans dauer state : standard dauer-formation assay using synthetic daumones and proteomic analysis of O-GIcNAc modifications / Jeeyong Lee, Kwang-Youl Kim, Kyoe-Jin Joo, Keekyeong Kim, Pan-Young Jeong, Young-Ki Paik.
  • 2007 CRCnetBASE
    edited by Barry D. Smith, Uma Gupta, B.S. Gupta.
  • 2013 ClinicalKey
    edited by Brian D. Coley.
    V. 1: Radiation bioeffects, risks, and radiation protection in medical imaging in children -- Complications of contrast media -- Magnetic resonance safety -- Embryology, anatomy, normal findings, and imaging techniques -- Prenatal, congenital, and neonatal abnormalities -- Orbit infection and inflammation -- Orbital neoplasia -- Nose and sinonasal cavities -- Embryology, anatomy, normal findings, and imaging techniques -- Congenital and neonatal abnormalities -- Infection and inflammation -- Neoplasia -- Embryology, anatomy, normal findings, and imaging techniques -- Prenatal, congenital, and neonatal abnormalities -- Infection and inflammation -- Neoplasia -- Thyroid and parathyroid -- Embryology, anatomy, normal findings, and imaging techniques -- Prenatal imaging -- Craniosynostosis, selected craniofacial syndromes, and other abnormalities of the skull -- Neoplasms, neoplasms-like lesions, and infections of the skull -- The mandible -- Traumatic lesions of the skull and face -- Embryology and brain development -- Magnetic resonance spectroscopy and positron emission tomography -- Diffusion-weighted magnetic resonance imaging: principles and implementation in clinical and research settings -- Functional magnetic resonance imaging -- Perfusion imaging and magnetoencephalography -- Prenatal imaging -- Neonatal brain injury -- Congenital brain malformations -- Hydrocephalus -- Inherited metabolic and neurodegenerative disorders -- Infection and inflammation -- Pediatric brain neoplasms -- Cerebrovascular disorders -- Stroke -- Neuroimaging in pediatric epilepsy -- Trauma -- Embryology, anatomy, and normal findings -- Spinal cord imaging techniques -- Prenatal imaging -- Congenital abnormalities of the spine -- Infections of the spine and spinal cord -- Spinal tumor and tumorlike conditions -- Vascular lesions -- Trauma -- Embryology, anatomy, and normal findings -- Imaging techniques -- Prenatal imaging and intervention -- Upper airway disease -- Lower large airway disease -- Congenital lung anomalies -- Pulmonary infection -- Neoplasia -- Diffuse lung disease -- Systemic conditions with lung involvement -- The mediastinum -- The chest wall -- The pleura -- The diaphragm -- Introductory embryology -- Cardiovascular anatomy and segmental approach to imaging of congenital heart disease -- Pediatric echocardiography -- Chest radiography in pediatric cardiovascular disease -- Pediatric cardiothoracic computed tomographic angiography -- Magnetic resonance imaging for congenital heart disease -- Nuclear cardiology -- Pediatric cardiac catheterization and electrophysiology -- Surgical considerations for congenital heart disease -- Prenatal imaging and therapy of congenital heart disease -- Abnormal pulmonary and systemic venous connections -- Septal defects -- Right heart lesions -- Conotruncal anormalies -- Congenital anomalies of the thoracic great arteries -- Coronary artery disease in children -- Syndromes and chromosomal anomalies -- Myocardial, endocardial, and pericardial diseases -- Cardiac and pericardial tumors -- Cardiovascular involvement by systemic diseases -- Acquired diseases of the thoracic great vessels -- V. 2: Embryology, anatomy, and normal findings -- Imaging techniques -- Prenatal gastrointestinal and hepatobiliary imaging -- The abdominal wall and peritoneal cavity -- Congenital hepatobiliary anomalies -- Acquired biliary tract disease -- Parenchymal liver disease -- Infectious causes of liver disease -- Neoplasia -- Vascular abnormalities of the liver -- Liver transplantation in children -- The spleen -- The pancreas -- Congenital and neonatal abnormalities -- Disorders of swallowing -- Acquired esophageal disorders -- Congenital and neonatal abnormalities -- Hypertrophic pyloric stenosis -- Acquired disorders -- Congenital and neonatal abnormalities -- Acquired abnormalities -- Acquired lesions of the small intestines -- Congenital and neonatal disorders -- Inflammatory and infectious diseases -- Intussusception -- Tumors and tumorlike conditions -- Abdominal trauma -- Embryology, anatomy, and variants of the genitourinary tract -- Imaging techniuqes -- Prenatal imaging and intervention -- Congenital and neonatal abnormalities -- Acquired abnormalities (stone disease and infection) -- Renal neoplasms -- Vascular conditions -- Renal failure and transplantation -- The ureter -- Vesicoureteral reflux -- Bladder and urethra -- Congenital and neonatal conditions -- Acquired conditions -- Genitourinary trauma -- Disorders of sex differentiation -- Abnormalities of the male genital tract -- Abnormalities of female genital tract -- Amenorrhea and abnormalities -- Embryology, anatomy, and normal findings -- Imaging techniques -- Prenatal musculoskeletal imaging -- Congenital anomalies of bone -- Skeletal dysplasias and selected chromosomal disorders -- Alignment disorders -- Scoliosis -- Developmental dysplasia of the hip -- Arthritis and differential inflammatory joint disorders -- Musculoskeletal infections -- Soft tissue and bone tumors -- Metabolic bone disease -- Endocrine disorders -- Skeletal manifestations of systemic disease -- Skeletal trauma -- Child abuse -- Sports medicine.
  • v. 1-2, 2008.
    editor-in-chief, Thomas L. Slovis.
    Status: Not Checked OutLane Catalog Record
  • ScienceDirect
    edited by Gerard Marriott.
    Also available: Print – 1998
  • 2013
    Evan Lloyd Guiney.
    In response to hyperosmotic shock, cells of the budding yeast Saccharomyces cerevisiae lose up to 50% of their volume. This drastic decrease in cell size results in excess plasma membrane, which forms large infoldings that must be quickly removed. How these plasma membrane invaginations are resolved to restore the cell surface is not well understood. We show that hyperosmotic shock activates calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, leading to restoration of normal membrane morphology. During hyperosmotic stress, actin patches (sites of endocytosis) become depolarized; we find that under these conditions calcineurin accumulates at sites of polarized growth and promotes actin patch repolarization. Hyperosmotic stress causes calcineurin to bind to the yeast synaptojanin Inp53/Sjl3 and dephosphorylate its proline rich tail. Dephosphorylation by calcineurin activates Inp53, which in turn dephosphorylates PI(4,5)P2 at the plasma membrane and promotes repolarization of the actin cytoskeleton. Consistently, cells lacking the partially redundant synaptojanins Inp51/Sjl1 and Inp52/Sjl2 require calcineurin for growth even in the absence of hyperosmotic stress, and display abnormal plasma membrane morphology when calcineurin activation of Inp53 is blocked. Finally, we find that calcineurin binding to Inp53 stimulates its association with the yeast amphiphysin Rvs167, suggesting model where calcineurin stimulates Inp53 and Rvs167 mediated membrane scission, promoting recovery from excess membrane stress and allowing resumption of polarized growth. In neurons, periods of intense synaptic vesicle release also result in excess membrane, and calcineurin stimulates association of synaptojanin with amphiphysin to promote synaptic vesicle endocytosis. Our findings in yeast suggest that stimulation of endocytic complex formation by Ca2+/calcineurin is a fundamental and conserved feature of the eukaryotic response to excess plasma membrane.
  • 2005/2006
    Monte Meier Winslow.
    Status: Not Checked OutLane Catalog Record
  • 2007
    Jeremy Josef Heit.
    Status: Not Checked OutLane Catalog Record
  • 2008
    Elena Maria Gallo.
    Status: Not Checked OutLane Catalog Record
  • 2010 Springer
    Debbie L. Hay, Ian M. Dickerson, editors.
  • 2007 ScienceDirect
    edited by Joachim Krebs, Marek Michalak.
    Also available: Print – 2007
  • 2015 Karger
    volume editors, Jeremy Allgrove, Nick J. Shaw.
    Voyages of discovery / Allgrove, J. -- Physiology of calcium, phosphate, magnesium and vitamin D / Allgrove, J. -- Physiology of bone / Grabowski, P. -- Radiology of osteogenesis imperfecta, rickets and other bony fragility states / Calder, A.D. -- Bone densitometry : current status and future perspective / Crabtree, N.; Ward K. -- A practical approach to hypocalcaemia in children / Shaw, N.J. -- Approach to the child with hypercalcaemia / Davies, J.H. -- A practical approach to vitamin D deficiency and rickets / Allgrove, J.; Shaw, N.J. -- A practical clinical approach to pediatric phosphate disorders / Imel, E.A. ; Carpenter, T.O. -- Primary osteoporosis / Arundel, P. ; Bishop, N. -- Osteoporosis in children with chronic disease / Hgler, W. ; Ward, L. -- Genetics of osteoporosis in children / van Dijk, F.S. -- A practical approach to children with recurrent fractures / Korula, S.; Titmuss, A.T.; Biggin A.; Munns, C.F. -- Miscellaneous bone disorders / Mughal, M.Z.; Padidela, R. -- Skeletal aspects of non-accidental injury / Johnson, K.; Bradshaw, K. -- Skeletal dysplasias: an overview / Offiah, A.C -- Drugs used in paediatric bone and calcium disorders / Cheung, M.S. -- Classification of disorders of bone and calcium metabolism / Allgrove J. -- Case histories / Katugampola, H. ; Saraff, V.; Kumaran, A. ; Allgrove, J.; Shaw, N.J.
  • 2009 Karger
    volume editors, Jeremy Allgrove, Nick Shaw.
  • 2009 WHO
    This book addresses whether or not calcium and magnesium ('hardness') in drinking water can contribute to preventing disease. It includes a comprehensive consensus view on what is known and what is not about the role and possible health benefit of calcium and magnesium in drinking-water. Also included is a series of chapters each authored by internationally renowned experts reviewing the state of the art in different aspects, including: global dietary calcium and magnesium intakes; the contribution of drinking water to calcium and magnesium intake; health significance of calcium and magnesium; role of drinking-water in relation to bone metabolism; epidemiological studies and the association of cardiovascular disease risks with water hardness and magnesium in particular; water production, technical issues and economics.--Publisher's description.
    Also available: Print – 2009
  • 2006 Springer
    edited by Chen Hsing Hsu.
  • 2010
    Natalia Gomez-Ospina.
    Abstract : Voltage-gated calcium channels are an important route of calcium entry into cells and are essential for converting electrical activity into biochemical events. In neurons these channels are vital for synaptic vesicle release and have been implicated in almost every activity-dependent process including survival, dendritic arborization, synaptic plasticity, and gene expression. One of the ways in which these channels regulate cellular behavior is by regulating gene expression but the mechanisms that link calcium channels to the transcription machinery are not well understood. In this thesis I show that a C-terminal fragment of CaV1.2, an L-type voltage-gated calcium channel, translocates to the nucleus and regulates transcription. I show that this calcium channel associated transcription regulator (CCAT), binds to a nuclear protein, associates with an endogenous promoter, and regulates the expression of a variety of endogenous genes that are important for the function of neurons and muscle cells. The nuclear localization of CCAT is regulated by changes in intracellular calcium on a time scale of minutes, suggesting that CCAT integrates information about the electrical activity of the cell. Together these findings reveal an entirely unexpected function for a well-characterized calcium channel. This works also addresses the question of how CCAT is generated. I show that CCAT is not released from proteolysis of full-length Cav1.2 channel but is generated from an mRNA that is transcribed from the 3' end of the Cav1.2 gene (CACNA1C). Consistent with this, I find that CCAT expression is independent of full-length channel protein and that exon 46 of the CACNA1C gene contains a promoter whose transcriptional activity is required for the expression of CCAT. Activity at this promoter, and consequently CCAT expression, is regulated spatially and temporally in the brain having highest expression during embryonic stages and in regions of the brain rich in inhibitory neurons. Analysis of 5' transcriptional starts from CACNA1C and Cap Analysis of Gene Expression (CAGE) tags from genome-wide studies show at least two mRNAs one of which encodes CCAT in vivo and a second transcript that is predicted to encode a membrane bound CCAT containing a voltage sensor. These findings reveal an unexpected mechanism by which CCAT is generated in neurons and provide a unique example by which two proteins with distinct biologic functions can be derived from a single gene. Such transcriptional phenomena may be at play in many other genes throughout the genome and has far reaching implications for prediction of gene products and interpretation of phenotypes in gene mutations and knockout studies.
  • 2016 Springer
    Juan A. Rosado, editor.
  • 2012 Springer
    Lee Yee-Ki, Siu Chung-Wah.
    Calcium Handling in hiPSC-Derived Cardiomyocytes -- Myocardial Infarction and Heart Failure -- Embryonic Stem Cells/Pluripotent Stem Cells -- Human Induced Pluripotent Stem Cell (hiPSC)-Derived Cardiomyocytes as a Source for Cardiac Regeneration -- Spontaneous Cardiac Differentiation -- Mesoderm Enrichment by Wnt-Signaling Growth Factors -- Endoderm-Like Cell (END)-2 Co-culture Method -- Calcium Homeostasis in Cardiomyocytes -- Sarcoplasmic Reticulum (SR) Governs Maturity of Cardiomyocytes -- SR Junctional Proteins Play a Role in Calcium Flux Between Cytosol and SR -- Spatial and Temporal Ca2+ Wavefront Dictated by T-Tubule Structure -- IP3-Mediated Calcium Release Contributes to Whole-Cell Calcium Transients -- Calcium Handling Properties of hES-Derived Cardiomyocytes -- Calcium Handling Properties of hiPSC-Derived Cardiomyocytes -- iPSC-Derived Cardiomyocyte as a Potential Platform for Disease Modeling of the Impaired Calcium Handling-Related Syndrome -- Disease Modeling of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) -- Mitochondrial Dysfunction-Related Cardiomyopathy-Impaired SR Ca2+ Reuptake -- Measurement of Cytosolic [Ca2+] by Fluorescence Confocal Microscopy -- Materials -- Calibration of Fluo-3 -- Isolation of hiPSC- and hESC-Derived Cardiomyocytes -- Recording of Cytosolic [Ca2+] -- RT-qPCR of Calcium Handling Proteins.
  • 2002. ScienceDirect
    volume editor, Mark P. Mattson.
  • 2006 Springer
    [edited by] Connie M. Weaver and Robert P. Heaney ; foreword by Lawrence G. Raisz.
    Bone as the calcium nutrient reserve / Robert P. Heaney -- Cellular functions and fluxes of calcium / Emmanuel M. Awumey and Richard D. Bukoski -- Nutritional epidemiology / Carol J. Boushey -- Clinical approaches for studying calcium metabolism and its relationship to disease / Connie M. Weaver -- Kinetic studies / Meryl E. Wastney, Yongdong Zhao, and Connie M. Weaver -- Requirements for what endpoint / Robert P. Heaney -- Dietary calcium: recommendations and intakes around the world / Anne C. Looker -- Food sources, supplements, and bioavailability / Connie M. Weaver and Robert P. Heaney -- The calcium economy / Robert P. Heaney -- Molecular regulation of calcium metabolism / James C. Fleet -- Influence of total diet on calcium homeostasis / Zamzam K. (Fariba) Roughead -- Influence of lifestyle choices on calcium homeostasis : smoking, alcohol, and hormone therapies / D. Lee Alekel and Oksana Matvienko -- Influence of physical activity on calcium and bone / Matthew Vukovich and Bonny Specker -- The case for a calcium appetite in humans / Michael G. Tordoff -- Infancy and childhood / Steven A. Abrams and Keli M. Hawthorne -- Pre-puberty and adolescence / Connie M. Weaver -- Calcium in pregnancy and lactation / Heidi J. Kalkwarf -- Calcium in systemic human health / Robert P. Heaney -- Calcium and oral health / Elizabeth A. Krall -- Dietary calcium and obesity / Dorothy Teegarden -- Polycystic ovarian syndrome and reproduction / Susan Thys-Jacobs -- Premenstrual syndrome / Susan Thys-Jacobs -- Calcium in the later years : osteoporosis / Bess Dawson-Hughes -- Calcium, vitamin D, and cancer / Peter R. Holt -- Dietary calcium and the metabolic syndrome / Dorothy Teegarden -- Calcium and phosphate control in patients with renal disease / David A. McCarron and Robert P. Heaney -- Hypertension and cardiovascular disease / David A. McCarron.
  • 2010 ScienceDirect
    edited by Michael Whitaker.
    Chapter 1. A Practical Guide to the Preparation of Ca2+ Buffers / Donald M. Bers, Chris W. Patton, Richard Nuccitelli -- Chapter 2. Photorelease Techniques for Raising or Lowering Intracellular Ca2+ / Robert Zucker -- Chapter 3. Making and Using Calcium-Selective Mini- and Microelectrodes / L. Hove-Madsen, S. Baudet, D.M. Bers -- Chapter 4. Construction, Theory, and Practical Considerations for using Self-referencing of Ca2+-Selective Microelectrodes for Monitoring Extracellular Ca2+ Gradients / Mark A. Messerli, Peter J.S. Smith -- Chapter 5. Practical Aspects of Measuring Intracellular Calcium Signals with Fluorescent Indicators / Joseph P.Y. Kao, Gong Li, Darryl A. Auston -- Chapter 6. Genetically Encoded Probes for Measurement of Intracellular Calcium / Michael Whitaker -- Chapter 7. Patch Clamp Methods for Studying Calcium Channels / David L. Armstrong, Christian Erxleben, Jody A. White -- Chapter 8. Nuclear Patch-Clamp Recording from Inositol 1,4,5-Trisphosphate Receptors / Taufiq Rahman, Colin W. Taylor -- Chapter 9. Confocal and Multiphoton Imaging of Intracellular Ca2+ / Godfrey Smith, Martyn Reynolds, Francis Burton, Ole Johan Kemi -- Chapter 10. The Use of Aequorins to Record and Visualize Ca2+ Dynamics: From Subcellular Microdomains to Whole Organisms / Sarah E. Webb, Kelly L. Rogers, Eric Karplus, Andrew L. Miller.
  • 2010 Springer Protocols
    edited by Alexei Verkhratsky and Ole H. Petersen.
    Principles of the CA2+ homeostatic/signalling system / A. Verkhratsky and O.H. Petersen -- CA2+ recordings: Hardware and software (from microscopes to cameras) / E.C. Toescu and J. Graham -- CA2+ imaging: Principles of analysis and enhancement / F. Mammano and M. Bortolozzi -- Bioluminescent CA2+ indicators / L. Fedrizzi and M. Brini -- Monitoring calcium levels with genetically encoded indicators / O. Garaschuk and O. Griesbeck -- Intracellular calcium-sensitive microelectrodes / R.C. Thomas -- CA2+ caging and uncaging / S.H. Kim and M.K. Park -- CA2+ imaging of intracellular organelles: Endoplasmic reticulum / R. Blum, O.H. Petersen and A. Verkhratsky -- CA2+ imaging of intracellular organelles: Mitochondria / L. Núñez [and others] -- CA2+ imaging of dendrites and spines / K. Holthoff -- In vivo CA2+ imaging of the living brain using multi-cell bolus loading technique / G. Eichhoff [and others] -- CA2+ imaging of glia / C. Lohr and J.W. Deitmer.
  • 2012 CRCnetBASE
    Sergey Dorozhkin.
    Due to a great chemical similarity with the biological calcified tissues, many calcium orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists use this property extensively to construct artificial bone grafts that are either entirely made of or only surface-coated with the biologically relevant calcium orthophosphates. Porous scaffolds made of calcium orthophosphates are very promising tools for tissue engineering applications. A comprehensive overview of calcium orthophosphates, this book highlights their importance and biomedical uses.
  • 2012 Springer
    Md. Shahidul Islam, [editor].
    "This volume ... [explores] topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to oocytes, zebrafish and plants. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative." --Excerpt from publisher's description.
    Also available: Print – 2012
  • 2006
    Nirav Rati Bhakta.
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer
    Yong-Xiao Wang, editor.
    Ryanodine and Inositol Trisphosphate Receptors/Ca2+ Release Channels in Airway Smooth Muscle Cells / Lin Mei, Yun-Min Zheng, and Yong-Xiao Wang -- Kv7 (KCNQ) Potassium Channels and L-type Calcium Channels in the Regulation of Airway Diameter / Kenneth L. Byron, Lioubov I. Brueggemann, Priyanka P. Kakad, and Jennifer M. Haick -- Transient Receptor Potential and Orai Channels in Airway Smooth Muscle Cells / Jun-Hua Xiao, Yong-Xiao Wang, and Yun-Min Zheng -- Large-conductance calcium-activated potassium channels / Hiroaki Kume -- Calcium-activated Chloride Channels / George Gallos and Charles W. Emala Sr. -- Local Calcium Signaling in Airway Smooth Muscle Cells / Quing-Hua Liu, Carlo Savoia, Yong-Xiao Wang -- Regulation of Airway Smooth Muscle Contraction by Ca2+ Signaling: Physiology Revealed by Microscopy Studies of Lung Slices / Michael J. Sanderson -- Temporal Aspects of Ca2+ Signaling in Airway Myocytes / Etienne Roux -- Mechanisms Underlying Ca2+ Store Refilling in Airway Smooth Muscle / Charlotte K. Billington, Ian P. Hall, and Carl P. Nelson -- Novel Mechanisms in Ca2+-homeostasis and Internal Store Refilling of Airway Smooth Muscle / Luke J. Janssen -- The Role of Mitochondria in Calcium Regulation in Airway Smooth Muscle / Philippe Delmotte, Li Jia, and Gary C. Sieck -- Role of Caveolae in the Airway / Christina M. Pabelick, Brij B. Singh, and Y.S. Prakash -- CD38 : Cyclic ADP-ribose-mediated Calcium Signaling in Airway Myocytes /Deepak A. Deshpande, Alonso Guedes, Mythili Dileepan, Timothy F. Walseth, and Mathur S. Kannan -- The Pathways and Signaling Cross-talk with Oxidant in Calcium Influx in Airway Smooth Muscle Cells / Lei Cai and Quinghua Hu -- Role of RhoA/Rho-kinase and Calcium Sensitivity in Airway Smooth Muscle Functions / Satoru Ito -- Role of Integrins in the Regulation of Calcium Signaling / Thai Tran and Chun Ming Teoh -- Sex Steroid Signaling in the Airway / Y.S. Prakash, Venkatachalem Sathish, and Elizabeth A. Townsend -- Regulation of Contractility in Immature Airway Smooth Muscle / Y.S. Prakash, Christina M. Pabelick, and Richard J. Martin -- Mathematical Modeling of Calcium Dynamics in Airway Smooth Muscle Cells / James Sneyd, Pengxing Cao, Xiahui Tan, and Michael J. Sanderson -- Effects of Inflammatory Cytokines on Ca2+ Homeostasis in Airway Smooth Muscle Cells / Hisako Matsumoto -- Ca2+ Signaling and P2 Receptors in Airway Smooth Muscle / Luis M. Montaño, Edgar Flores-Soto, and Carlos Barajas-López -- Calcium Signaling in Airway Smooth Muscle Remodeling / Tengyao Song, Yun-min Zheng, and Yong-Xiao Wang -- Regulation of Intracellular Calcium by Bitter Taste Receptors on Airway Smooth Muscle / Deepak A. Deshpande and Stephen B. Liggett -- Modulation of Airway Smooth Muscle Contractile Function by TNFa and IL-13 and Airway Hyper-responsiveness in Asthma / Yassine Amrani -- Airway Smooth Muscle Malfunction in COPD / Yunchao Su.
  • 2006 CRCnetBASE
    edited by James W. Putney, Jr.
  • 2012 Springer Protocols
    edited by David G. Lambert, Richard D. Rainbow.
    Fluorescent measurement of [Ca2+]c : basic practical considerations / Alec W.M. Simpson -- Measurement of [Ca2+]i in whole cell suspensions using fura-2 / Anish Patel [and others] -- Confocal microscopy : theory and applications for cellular signaling / Stephen C. Tovey [and others] -- Ratiometric Ca2+ measurements using the FlexStation® scanning fluorometer / Ian C.B. Marshall, Izzy Boyfield, and Shaun McNulty -- Measuring Ca2+ changes in multiwell format using the fluorometric imaging plate reader (FLIPR®) / Ian C.B. Marshall, Davina E. Owen, and Shaun McNulty -- Ratiometric [Ca2+]i measurements in adherent cell-lines using the NOVOstar microplate reader / Benjamin D. Hunt and David G. Lambert -- Whole-cell patch-clamp recording of voltage-sensitive Ca2+ channel currents in single cells : heterologous expression systems and neurones / Jon Brown [and others] -- Combined calcium fluorescence recording with ionic currents in contractile cells / Richard D. Rainbow -- Measurement of phospholipase C by monitoring inositol phosphates using [3H]inositol labeling protocols in permeabilized cell / Alison Skippen, Philip Swigart, and Shamshad Cockcroft -- Single-cell imaging techniques for the real-time detection of IP3 in live cells / Carl P. Nelson -- Measurement of inositol(1,4,5)trisphosphate using a stereospecific radioreceptor mass assay / Darren Smart -- Measurement of [Ca2+]i in smooth muscle strips using front-surface fluorimetry / Hideo Kanaide and Katsuya Hirano -- Calcium measurements from whole heart using rhod-2 / Bum-Rak Choi -- Measurement of changes in endothelial and smooth muscle Ca2+ in pressurized arteries / Kim A. Dora and Michael A. Hill -- Single cell and subcellular measurements of intracellular Ca2+ concentration / John G. McCarron [and others] -- Simultaneous analysis of intracellular pH and Ca2+ from cell populations / Raul Martinez-Zaguilan [and others] -- Measurements of Ca2+ concentration with recombinant targeted luminescent probes / Denis Ottolini, Tito Calì, and Marisa Brini -- Chimeric G proteins in fluorimetric calcium assays : experience with opioid receptors / Valeria Camarda and Girolamo Calo -- Compartmentalizing genetically encoded calcium sensors / David A. Williams, Mastura Monif, and Kate L. Richardson -- Measurement of cytosolic-free Ca2+ in plant tissue / Martin R. McAinsh and Carl K.-Y. Ng -- Measurement of Ca2+-ATPase activity (in PMCA and SERCA1) / Danuta Kosk-Kosicka.
  • 2013 Springer
    Lars Kaestner.
    Summary -- Introduction -- Direct evidence - the digital approach -- Fluorescence-based visualisation -- Aequorin-based measurements -- Measurement of calcium transport across membranes -- Molecular biology based approaches -- Manipulation of calcium -- Calcium-induced function -- Calcium signalling in cardiac myocytes -- Calcium signalling in red blood cells -- Perspective -- Calcium Signalling Methodology -- Non-linear and ultra high-speed imaging for explorations of the murine and human heart -- A system for optical high resolution screening of electrical excitable cells -- Concepts for optical high content screens of excitable primary isolated cells -- A primary culture system for sustained expression of a calcium sensor in preserved adult rat ventricular myocytes -- Calcium imaging of individual erythrocytes: Problems and approaches -- Calcium Signalling in Cardiac Myocytes -- Reduced Cardiac L-Type Ca²+ Current in Cav€ ₂ -/- Embryos Impairs Cardiac Development and Contraction With Secondary Defects in Vascular Maturation -- Overexpression of junctin causes adaptive changes in cardiac myocyte Ca²+ signaling -- Remodelling of Ca²+ handling organelles in adult rat ventricular myocytes during longterm culture -- Functional and morphological preservation of adult ventricular myocytes in culture by sub-micromolar cytochalasin D supplement -- Calcium Signalling in Red Blood Cells -- The non-selective voltage-activated cation channel in the human red blood cell membrane: reconciliation between two conflicting reports and further characterisation -- Ion channels in the human red blood cell membrane: Their further investigation and physiological relevance -- Prostaglandin E₂ activates channelmediated calcium entry in human erythrocytes: An indication for a blood clot formation supporting process -- Functional NMDA receptors in rat erythrocytes -- Stimulation of human red blood cells leads to Ca²+-mediated intercellular adhesion -- Lysophospatidic acid induced red blood cell aggregation in vitro -- Regulation of phosphatidylserine exposure in red blood cells -- Cation Channels in Erythrocytes - Historical and Future Perspective.
  • 2007 Springer
    edited by Ernesto Carafoli and Marisa Brini.
    Annexinopathies / M.J. Hayes ... [et al.] -- Calpains and human disease / I. Bertipaglia and E. Carafoli -- Gelsolin and diseases / L. Spinardi and W. Witke -- Guanylate cyclase-activating proteins and retina disease / W. Baehr and K. Palczewski -- Pathologies involving the S100 proteins and rage / C.W. Heizmann ... [et al.] -- The calcium-sensing receptor: Physiology, pathophysiology and CaR-based therapeutics / E.M. Brown -- Physiological roles of the Ca2+/CaM-dependent protein kinase cascade in health and disease / J. Colomer and A.R. Means -- Calcium channelopathies: Voltage-gated calcium channels / P.J. Adams and T.P. Snutch -- TRP channels in disease / S.E. Jordt and B.E. Ehrlich -- Diseases associated with altered ryanodine receptor activity / W.J. Durham ... [et al.] -- Inositol 1,4,5-tripshosphate receptor, calcium signalling and Huntington's disease / I. Bezprozvanny -- SERCA pumps and human diseases / A. Hovnanian -- The plasma membrane calcium ATPase and disease / B.L. Tempel and D.J. Shilling -- Diseases involving the Golgi calcium pump / J. Vanoevelen ... [et al.] -- Calcium signalling and cancer cell growth / T. Capiod ... [et al.] -- Calcium misregulation and the pathogenesis of muscular dystrophy / F.W. Hopf ... [et al.] -- Calcium and cell death / A. Verkhratsky -- Calcium and cell death: The mitochondrial connection / P. Bernardi and A. Rasola -- Role of calcium in the pathogenesis of Alzheimer's disease and transgenic models / K.N. Green ... [et al.] -- Calcium and cardiomyopathies / E.G. Kranias and D.M. Bers -- Calcium signalling and calcium transport in bone disease / H.C. Blair ... [et al.].
  • v. 1-2, 2002. Springer Protocols
    v. 2, 2002 Springer Protocols
    edited by Hans J. Vogel.
    v. 1. Reviews and case studies -- v. 2. Methods and techniques.
  • 2013 Springer Protocols
    edited by Claus W. Heizmann.
    Measurement of intracellular Ca2+ concentration in single cells using ratiometric calcium dyes -- Divers models of divalent cation interaction to calcium-binding proteins: Techniques and anthology -- Probing Ca2+-binding capability of viral proteins with the EF-hand motif by grafting approach -- New aspects of calmodulin-calmodulin binding domains recognition -- Purification and characterization of the human cysteine-rich S100A3 protein and its pseudo citrullinated forms expressed in insect cells -- X-ray structural analysis of S100 proteins -- Purification and stable isotope labeling of the calcium- and integrin-binding protein 1 for structural and functional NMR studies -- Analysis of calcium-induced conformational changes in calcium-binding allergens and quantitative determination of their IgE binding properties -- Longistatin, an EF-hand Ca2+-binding protein from vector tick: Identification, purification, and characterization -- Super-resolution microscopy of the neuronal calcium-binding proteins calneuron-1 and caldendrin -- NMR studies of the interaction of calmodulin with iq motif peptides -- Biochemical and immunological detection of physical interactions between penta-ef-hand protein ALG-2 and its binding partners -- Measuring binding of S100 proteins to RAGE by surface plasmon resonance -- Phage display selection of peptides that target calcium-binding proteins -- RAGE-mediated cell signaling -- RAGE splicing variants in mammals -- Screening for novel calcium-binding proteins that regulate cardiac hypertrophy: CIB1 as an example -- In vivo screening of S100B inhibitors for melanoma therapy -- Arrayed primer extension microarray for the analysis of genes associated with congenital stationary night blindness -- Nesfatin-1: Its role in the diagnosis and treatment of obesity and some psychiatric disorders -- Human cell line authentication: The critical first step in any project using human cell lines -- Detection of Ca2+-binding S100 proteins in human saliva by HPLC-ESI-MS -- Clinical use of the calcium-binding S100B protein -- Sensible use of high-sensitivity troponin assays -- S100a1 gene therapy in small and large animals.
  • 2010 ScienceDirect
    Frank H. Stephenson.
    Chapter 1. Scientific notation and metric prefixes -- Chapter 2. Solutions, mixtures, and media -- Chapter 3. Cell growth -- Chapter 4. Working with bacteriophages -- Chapter 5. Nucleic acid quantification -- Chapter 6. Labeling nucleic acids with radioisotopes -- Chapter 7. Oligonucleotide synthesis -- Chapter 8. The polymerase chain reaction (PCR) -- Chapter 9. The real-time polymerase chain reaction (RT-PCR) -- Chapter 10. Recombinant DNA -- Chapter 11. Protein -- Chapter 12. Centrifugation -- Chapter 13. Forensics and paternity.
  • 2013
    Asian & Pacific Islander American Health Forum.
  • Google Books
    State of California, Department of Health ; prepared by the staff of the Crippled Children Services Section and Center for Health Statistics.
  • prepared by the Foundation for Taxpayer & Consumer Rights.
    Introduction -- Your rights to continuous care, second opinions, referrals and information -- Your right to informed consent -- Your rights to medical records and confidentiality -- Your right to emergency medical care -- Your rights to coverage of pre-existing conditions -- Your rights to file grievances with your health plan and the Department of Managed Health Care -- Your rights to have your HMO's decisions independently reviewed and to sue Your HMO --Your rights to appeal and litigate benefit denials under ERISA -- Health care coverage options -- Appendix A: Department of Managed Health Care's consumer complaint form -- Appendix B: Vital steps to receiving the health care you need, a checklist -- Appendix C: Sample letter -- Appendix D: Strategic advice for patients: tactics to use and understand -- Appendix E: Useful code sections of the California Knox-Keene Health Care Service Plan Act of 1975 and regulations -- Glossary.
  • 1977-82. Google Books
    State of California, Dept. of Rehabilitation
    Part 1. Reference and planning information -- Part 2. Facilities inventory.
    Also available: Print – 1977-82.
  • 2002 ScienceDirect
    Edward J. Masoro.
  • 2010 Springer
    Arthur V. Everitt, Suresh I.S. Rattan, David G. Le Couteur, Rafael de Cabo, editors.
    Part 1. CALORIE RESTRICTION IN DIFFERENT SPECIES -- History of Caloric Restriction, Aging and Longevity / Edward J. Masoro -- Food Intake, Life Style, Aging and Human Longevity / Arthur V. Everitt, Leonie K. Heilbronn and David G. Le Couteur -- Okinawa: A Naturally Calorie Restricted Population / Matthew W. Rosenbaum, Bradley J. Willcox, D. Craig Willcox and Makoto Suzuki -- Aging and the Effect of Calorie Restriction in Rhesus Monkeys / Ilhem Messaoudi, Jennifer E. Young, Ricki J. Colman, April M. Handy and George S. Roth, et al. -- Dietary Restriction and Aging in Drosophila Melanogaster / Luc Poirier, Rafael de Cabo and Sige Zou -- Aging and Dietary Restriction: The Yeast Paradigm / Min Wei, Federica Madia, Rafael de Cabo and Valter D. Longo -- The Nutritional Geometry of Aging / Stephen J. Simpson and David Raubenheimer -- Part 2. BIOCHEMICAL AND METABOLIC MECHANISMS OF CALORIE RESTRICTION -- Oxidative Stress, Dietary Restriction and Aging / Brian J. Merry and Catherine E. Ash -- Calorie Restriction Mimetics and Aging / Brian J. Morris -- Will Calorie Restriction Stave Off Age-Related Brain Dysfunction, Specifically to Learning and Memory? A Review and Critique of the Rodent Literature / Edward L. Spangler, Jeffrey Long, Bennett Kelley-Bell, Marshall Miller and Robin K. Minor, et al. -- The Aging Liver and the Effects of Long Term Caloric Restriction / David G. Le Couteur, David A. Sinclair, Victoria C. Cogger, Aisling C. McMahon and Alessandra Warren, et al. -- Food Restriction, Hormones, Genes and Aging / Arthur V. Everitt, Holly M. Brown-Borg, David G. Le Couteur and Andrzej Bartke -- Hormesis as a Mechanism for the Anti-Aging Effects of Calorie Restriction / Suresh I.S. Rattan and Dino Demirovic -- Part 3. CALORIE RESTRICTION IN THE CLINICAL SETTING -- Calorie Restriction and Obesity / Krista A. Varady -- Caloric Restriction and Cardiovascular Disease / Anna Csiszar, Rafael de Cabo and Zoltan Ungvari -- The Effect of Caloric Restriction on Physiological, Psychological and Behavioral Outcomes in Humans: Results from CALERIE / Leanne M. Redman and Eric Ravussin -- Calorie Restriction and Cancer: An Update / Robin K. Minor, R. Michael Anson and Rafael de Cabo -- Conclusion: Human Calorie Restriction and Anti-aging Therapy / Arthur V. Everitt, Leonie K. Heilbronn, Brian J. Morris, Holly M. Brown-Borg and Brian J. Merry, et al.
  • 2016 ScienceDirect
    edited by Andrew L. Feig.
  • 2011
    [edited by Beth Van Schaack, Daryn Reicherter, Youk Chhang ; managing editor, Autumn Talbott].
    Status: Not Checked OutLane Catalog Record
  • 2008
    editor-in-chief, Peter A. Singer, executive editor, A.M. Viens.
    Status: Not Checked OutLane Catalog Record
  • 2009 CUP
    edited by Robert B. Baker, Laurence B. McCullough.
    pt. I. An introduction to the history of medical ethics -- 1. What is the history of medical ethics? / Robert B. Baker and Laurence B. McCullough -- 2. Bioethics and history / Martin S. Pernick -- pt. II. A chronology of medical ethics / Robert B. Baker and Laurence B. McCullough -- pt. III. Discourses of medical ethics through the life cycle -- 3. Medical ethics through the life cycle in Hindu India / Katherine K. Young -- 4. Medical ethics through the life cycle in Buddhist India / Katherine K. Young -- 5. Medical ethics through the life cycle in China / Jing-Bao Nie -- 6. Medical ethics through the life cycle in Japan / Rihito Kimura and Shizu Sakai -- 7. Medical ethics through the life cycle in Europe and the Americas / Robert B. Baker and Laurence B. McCullough -- 8. Medical ethics through the life cycle in the Islamic Middle East / Ilhan Ilkilic -- pt. IV. Discourses of religion on medical ethics -- 9. The discourses of Hindu medical ethics / Katherine K. Young -- 10. The discourses of Buddhist medical ethics / Katherine K. Young -- 11. The discourses of Confucian medical ethics / Ruiping Fan -- 12. The discourses of early Christian medical ethics / Darrel W. Amundsen -- 13. The discourses of Orthodox Christian medical ethics / H. Tristram Engelhardt, Jr. -- 14. The discourses of Roman Catholic medical ethics / Darrel W. Amundsen -- 15. The discourses of Protestant medical ethics / Gary B. Ferngren -- 16. The discourses of Jewish medical ethics / Noam J. Zohar -- 17. The discourses of Islamic medical ethics / Ilhan Ilkilic -- pt. V. The discourses of philosophy on medical ethics -- 18. The discourses of philosophical medical ethics / Robert B. Baker and Laurence B. McCullough -- pt. VI. The discourses of practitioners on medical ethics -- 19. The discourses of practitioners in Africa / Angela Amondi Wasunna -- 20. The discourses of practitioners in India / Katherine K. Young -- 21. The discourses of practitioners in China / Jing-Bao Nie -- 22. The discourses of practitioners in Japan / Rihito Kimura and Shizu Sakai -- 23. The discourses of practitioners in ancient Europe / Heinrich von Staden -- 24. The discourses of European practitioners in the tradition of the Hippocratic texts / Vivian Nutton -- 25. The discourses of practitioners in ninth- to fourteenth-century Middle East / Ursula Weisser -- 26. The discourses of practitioners in medieval and renaissance Europe / Klaus Bergdolt -- 27. The discourses of practitioners in sixteenth- and seventeenth-century Europe / Andrew Wear -- 28. The discourses of practitioners in eighteenth-century France and Germany / Mary Lindemann -- 29. The discourses of practitioners in eighteenth-century Spain / Diego Gracia -- 30. The discourses of practitioners in eighteenth-century Britain / Laurence B. McCullough -- 31. The discourses of practitioners in eighteenth-century North America / Chester R. Burns -- 32. The discourses of practitioners in nineteenth- and twentieth-century France / Robert A. Nye -- 33. The discourses of practitioners in nineteenth- and twentieth-century Spain / Diego Garcia -- 34. The discourses of practitioners in nineteenth- and twentieth-century Germany / Andreas-Holger Maehle and Ulrich Tröhler -- 35. The discourses of practitioners in eighteenth- to twentieth-century Russia and Soviet Union / Boleslav L. Lichterman and Mikhail Yarovinsky -- 36. The discourses of practitioners in nineteenth- and twentieth-century Britain and the United States / Robert B. Baker -- 37. The discourses of practitioners in the modern and contemporary Islamic Middle East / Vardit Rispler-Chaim -- pt. VII. The discourses of bioethics -- 38. The discourses of bioethics in the United States / Albert R. Jonsen -- 39. The discourses of bioethics in United Kingdom / Kenneth Body -- 40. The discourses of bioethics in Western Europe -- 41. The discourses of bioethics in post-communist Eastern Europe / Eugenijus Gefenas -- 42. The discourses of bioethics in Latin America / José Alberto Mainetti -- 43. The discourses of bioethics in East Asia / Ruiping Fan and Jiro Nudeshima -- 44. The discourses of bioethics in South Asia / Katherine K. Young -- 45. The discourses of bioethics in sub-Saharan Africa / Angela Amondi Wasunna -- pt. VIII. Discourses on medical ethics and society -- A. Ethical and legal regulation of medical practice and research -- 46. The medical market place, the patient, and the absence of medical ethics in early modern Europe and North America / Mary E. Fissell -- 47. The legal and quasilegal regulation of practitioners and practice in the United States / Stephen R. Latham and James C. Mohr -- 48. The ethics of experimenting on animal subjects / Andreas-Holger Maehle -- 49. The ethics of experimenting on human subjects / Susan E. Lederer -- 50. The historical development of the international codes of ethics for human subjects research / Ulrich Tröhler -- 51. International ethics of human subjects research in the late twentieth century / Baruch A. Brody -- B. Medical ethics, imperialism, and the nation-state -- 52. Colonialism, imperialism, and the history of Latin American medical ethics / Juan Carlos Tealdi -- 53. Japanese doctors' experimentation, 1932-1945, and medical ethics / Jing-Bao Nie, Takashi Tsuchiya, and Lun Li -- 54. Medical ethics and Nazism / Ulf Schmidt -- 55. Medical ethics and communism in the Soviet Union / Boleslav L. Lichterman -- 56. Medical ethics and communism in Eastern Europe / Bela Blasszauer -- 57. The ethics of military medical research in the United States during the Cold War / Jonathan D. Moreno -- 58. Medical ethics and the military in South Africa during apartheid : judging history / Wendy Orr -- C. Medical ethics and health policy -- 59. Making distinctions "natural" : the science of social categorization in the United States in the twentieth century / Dorothy Nelkin and David Rosner -- 60. History of public health ethics in the United States / Barron H. Lerner and Ronald Bayer -- 61. Ethics and health policy in the United Kingdom and the United States : legislation and regulation / Daniel M. Fox and Rudolf Klein -- 62. Ethical issues in organ transplantation in the United States / Judith P. Swazey and Renée C. Fox -- 63. Defining and redefining life and death / Robert M. Veatch -- Appendix. Biographies : who was who in the history of medical ethics.
  • 2015 Springer Protocols
    edited by Manuela Zaccolo.
    Simultaneous assessment of cAMP signaling events in different cellular compartments using FRET-based reporters / Alex Burdyga and Konstantinos Lefkimmiatis -- Recording intracellular cAMP levels with EPAC-based FRET sensors by fluorescence lifetime imaging / Marcel Raspe, Jeffrey Klarenbeek, and Kees Jalink -- Novel approach combining real-time imaging and the patch-clamp technique to calibrate FRET-based reporters for cAMP in their cellular microenvironment / Andreas Koschinski and Manuela Zaccolo -- Structure-based, in silico approaches for the development of novel cAMP FRET reporters / Matías Machado and Sergio Pantano -- Automated image analysis of FRET signals for subcellular cAMP quantification / Silas J. Leavesley [and others] -- Channel-based reporters for cAMP detection / Thomas C. Rich [and others] -- Imaging sub-plasma membrane cAMP dynamics with fluorescent translocation reporters / Anders Tengholm and Olof Idevall-Hagren -- Adenoviral transduction of FRET-based biosensors for cAMP in primary adult mouse cardiomyocytes / Oliver Lomas [and others] -- Generation of transgenic mice expressing FRET biosensors / Daniela Hübscher and Viacheslav O. Nikolaev -- Photoactivatable adenylyl cyclases (PACs) as a tool to study cAMP signaling in vivo : an overview / Marina Efetova and Martin Schwärzel -- Selective disruption of the AKAP signaling complexes / Eileen J. Kennedy and John D. Scott -- Screening for small molecule disruptors of AKAP-PKA interactions / Carolin Schächterle [and others] -- Structure-based bacteriophage screening for AKAP- selective PKA regulatory subunit variants / Ryan Walker-Gray and Matthew G. Gold -- Yeast-based high-throughput screen for modulators of phosphodiesterase activity / Ana Santos de Medeiros and Charles S. Hoffman -- Separation of PKA and PKG signaling nodes by chemical proteomics / Eleonora Corradini, Albert J.R. Heck, and Arjen Scholten -- Development of computational models of cAMP signaling / Susana R. Neves-Zaph and Roy S. Song.
  • 2016 ClinicalKey
    S. Terry Canale, James H. Beaty, Frederick M. Azar.
    Ideal for orthopaedic surgeons who need a practical resource covering the top procedures in the field, Campbell's Core Orthopaedic Procedures utilizes a succinct format that focuses solely on the surgical techniques critical in helping achieve optimal patient outcomes. Featuring step-by-step procedures used at the Campbell Clinic, this new resource offers practical, concise solutions for every patient scenario.
  • 2013 ClinicalKey
    [edited by] S. Terry Canale, James H. Beaty ; editorial assistance by Kay Daugherty and Linda Jones ; art coordination by Barry Burns.
    v. 1. General principles -- Reconstructive procedures of the hip in adults -- Reconstructive procedures of the knee in adults -- Reconstructive procedures of the ankle in adults -- Reconstructive procedures of the shoulder and elbow in adults -- Amputations -- Infections -- Tumors -- v. 2. Congenital and developmental disorders -- Nervous system disorders in children -- Fractures and dislocations in children -- The spine -- v. 3. Sports medicine -- Arthroscopy -- Fractures and dislocations in adults -- v. 4. Peripheral nerve injuries -- Microsurgery -- The hand -- The foot and ankle.
  • v. 1-4, 2008.
    [edited by] S. Terry Canale, James H. Beaty ; editorial assistance by Kay Daugherty and Linda Jones ; art coordination by Barry Burns.
    Status: Not Checked OutLane Catalog Record
  • 2016 ClinicalKey
    editor-in-chief, Alan J. Wein ; [editors] Louis R. Kavoussi, Alan W. Partin, Craig A. Peters
    V. 1 -- Pt. I: Clinical decision making -- Pt. II: Basics of urologic surgery -- Pt. III: Infections and inflammation -- Pt. IV: Molecular and cellular biology -- Pt. V: Reproducitve and sexual function -- Pt. VI: Male genitalia -- V. 2 -- Pt. VII: Renal physiology and pathophysiology -- Pt. VIII: Upper urinary tract obstruction and trauma -- Pt. IX: Urinary lithiasis and endourology -- Pt. X: Neoplasms of the upper urinary tract -- Pt. XI: The adrenals -- V. 3 -- Pt. XII: Urine transport, storage, and emptying -- Pt. XIII: Benign and malignant bladder disorders -- Pt. XIV: The prostate -- V. 4 -- Pt. XV: Pediatric urology -- Sect. A: Development and prenatal urology -- Sect. B: Basic principles -- Sect. C: Upper urinary tract conditions -- Sect. D: Lower urinary tract conditions -- Sect. E: Genitalia -- Sect. F: Reconstruction and trauma -- Sect. G: Oncology.
  • 2007
    editor-in-chief, Alan J. Wein ; editors, Louis R. Kavoussi ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • v. 1-4, 2007.
    editor-in-chief, Alan J. Wein ; editors, Louis R. Kavoussi, Andrew C. Novick, Alan W. Partin, Craig A. Peters.
    Status: Not Checked OutLane Catalog Record
  • 2005 Springer
    edited by Val R. Adams and Thomas G. Burke.
    Mechanism of action of topoisomerase I poisons / Leroy F. Liu and Shyamal D. Desai -- Crystallographic insight into the mechanism of drug-induced topoisomerase I DNA damage / Alex B. Burgin, Jr., Bart L. Staker, and Lance Stewart -- Inhibitors of topoisomerase I function / Sidney M. Hecht -- Cytotoxic mechanisms of the topoisomerase I inhibitors / Yves Pommier ... [et al.] -- Biochemical and genetic analyses of DNA topoisomerase I-mediated DNA damage / Robert C.A.M. Van Waardenburg and Mary-Ann Bjornsti -- Preclinical models for evaluating topoisomerase-I targeted drugs / Aarti S. Juvekar ... [et al.] -- Mechanisms of resistance to camptothecins / Zeshaan A. Rasheed and Eric H. Rubin -- Recent advances in camptothecin drug design and delivery strategies / Thomas G. Burke ... [et al.] -- Clinical experience with 9-aminocamptothecin: lessons for new drug development / Chris H. Takimoto -- Clinical studies of rubitecan (9-nitro 20(s) camptothecin) / Hilary Hewes, Judith A. Smith, and Claire Verschraegen -- Irinotecan: current clinical status and pharmacological aspects / Laurent P. Rivory -- Clinical experience with topotecan / Aimee K. Bence and Val R. Adams -- The clinical development of lurtotecan: experience with water-soluble and liposomal forms / Keith T. Flaherty ... [et al.] -- Preclinical and clinical development of dx-8951f (exatecan mesylate): a hexacyclic camptothecin analog / Eric K. Rowinsky -- Camptothecins in the treatment of primary brain tumors / Clinton F. Stewart, Markos Leggas, and Henry S. Friedman -- Camptothecins in the treatment of lung cancer / Pankaj Kumar ... [et al.] -- Use of camptothecins in the treatment of leukemia and related disorders / Bejamin M.F. Mow and Scott H. Kaufmann.
  • 2008
    Patrice Lindsay, Mark Bayley, Chelsea Hellings, Michael Hill ...[et al.].
  • Cote, R.
  • 1982-
    Frederick F. Becker, editor.
    Status: Not Checked OutLane Catalog Record
    v. 1. Etiology : chemical and physical carcinogenesis.
  • 1982 NLM
    Also available: Print – 1982
  • 2006 Springer
    edited by Leon P. Bignold.
  • 2006
    Michelangelo Delfino and Mary E. Day.
    Status: Not Checked OutLane Catalog Record
    Once upon a time -- A tale of two killers -- Radiography -- Kill or be killed -- A big problem with cancer -- Cancerous tissues -- Genital system cancers -- Urinary system cancers -- Chest and abdomen cancers -- Head and neck cancers -- Digestive system cancers -- Benign tumors and other maladies.
  • 2013 Karger
    volume editor, Martine Extermann.
    Chronic mechanistic target of rapamycin inhibition : preventing cancer to delay aging, or vice versa? / Sharp, Z.D.; Curiel, T.J.; Livi, C. -- Senescent cells and their secretory phenotype as targets for cancer therapy / Velarde, M.C.; Demaria, M.; Campisi, J. -- Cancer vaccination at older age / Gravekamp, C. -- Immunology of aging and cancer development / Fulop, T. ... [et al.] -- Metabolic syndrome and cancer : from bedside to bench and back / Extermann, M. -- Frailty : a common pathway in aging and cancer / Balducci, L. -- Targeting age-related changes in the biology of acute myeloid leukemia : is the patient seeing the progress? / Vey, N. -- Comprehensive geriatric assessment in oncology / Mohile, S.G.; Magnuson, A. -- Pharmacology of aging and cancer : how useful are pharmacokinetic tests? / Lichtman, S.M. -- Surgery in older cancer patients : recent results and new techniques : worth the investment? / Van Leeuwen, B.L.; Huisman, M.G.; Audisio, R.A. -- Organizing the geriatrician/oncologist partnership : one size fits all? practical solutions / Holmes, H.M.; Albrand, G. -- Geriatric oncology nursing : beyond standard care / Overcash, J. -- Exercise for older cancer patients : feasible and helpful? / Klepin, H.D.; Mohile, S.G. ; Mihalko, S. -- Aging and cancer : addressing a nation's challenge / Brochot, J.-M.; Le Quellec-Nathan, M.; Buzyn, A.
  • 2012 Wiley
    [edited by] Keith Bellizzi, Margot Gosney.
    pt. I. Cancer and aging in context -- pt. II. Strategies for cancer prevention in older adults -- pt. III. Cancer screening guidelines for older adults -- pt. IV. Cancer treatment -- pt. V. Common cancers in the elderly -- pt. VI. Cancer survivorship and aging -- pt. VII. End-of-life care -- pt. VIII. Emerging issues.
  • 1980-
    edited by Stanley T. Crooke, Archie W. Prestayko ; editorial assistant Nancy Alder.
    Status: Not Checked OutLane Catalog Record
    v. 1, Introduction to neoplasia and antineoplastic chemotherapy ; v. 2, Introduction to clinical oncology ; v. 3, Antineoplastic agents ;
  • NLM
    a report of the Surgeon General, 1985.
    Also available: Print – 1985
  • 2010 Springer
    Nathan A. Berger, editor.
    1. Obesity and Cancer Epidemiology -- 2. Obesity and Cancer: Epidemiology in Racial/Ethnic Minorities -- 3. Obesity and Cancer in Asia -- 4. Genetic Epidemiology of Obesity and Cancer -- 5. Obesity and Cancer: Overview of Mechanisms -- 6. Caloric Restriction and Cancer -- 7. Physical Activity and Cancer -- 8. Energy Balance, Cancer Prognosis, and Survivorship -- 9. Behavior, Energy Balance, and Cancer: An Overview -- 10. Geographic and Contextual Effects on Energy Balance-Related Behaviors and Cancer.
  • 2016 Springer
    Edmund S. Sabanegh, Jr., editor.
    1. Demographics of cancer in the reproductive age male -- 2. Demographics of cancer in the reproductive age female -- 3. Physiology of spermatogenesis: opportunities for disruption -- 4. Fertility assessment in the male -- 5. Fertility assessment in the female -- 6. Fertility conditions associated with cancer development -- 7. Chemotherapy and fertility -- 8. Radiation therapy and fertility -- 9. Sperm banking for cancer patients --10.Fertility preservation strategies in the male cancer patient -- 11. Fertility preservation in the female cancer patient -- 12. Cancer treatment in pregnancy -- 13. Surgical approaches for sperm harvest in the azoospermic cancer patient -- 14. Stem cells and fertility -- 15. The role of assisted reproduction in the cancer patient -- 16. Third party reproduction -- Index.
  • 2010 Springer
    Manuel L. Penichet, Erika Jensen-Jarolim, editors.
  • 2014 Wiley
    edited by Dr. Yusuke Hiraku, Dr. Shosuke Kawanishi, Dr. Hiroshi Ohshima.
    Infection, inflammation, and cancer: overview / Hiroshi Ohshima, Noriyuki Miyoshi, and Susumu Tomono -- Stem cell theory and inflammation-related cancer / Toshihiko Tanno and William Matsui -- Epithelial-mesenchymal transition: a link between cancer and inflammation / Jonas Fuxe and Mikael C.I. Karlsson -- Role of nitrative DNA damage in inflammation-related carcinogenesis / Yusuke Hiraku and Shosuke Kawanishi -- Lipid peroxidation-derived DNA adducts and the role in inflammation-related carcinogenesis / Helmut Bartsch and Urmila Jagadeesan Nair -- Level of inflammation-related DNA adducts in human tissues / Tomonari Matsuda, Pei-Hsin Chou, and Haruhiko Sugimura -- Toll-like receptors: role in inflammation and cancer / Sarang Tartey and Osamu Takeuchi -- Inflammasomes and inflammation / Kaiwen W. Chen, Ayanthi A. Richards, Alina Zamoshnikova, and Kate Schroder -- Activation-induced cytidine deaminase: an intrinsic genome modulator in inflammation-associated cancer development / Hiroyuki Marusawa and Tsutomu Chiba -- MicroRNA and inflammation-related cancer / Zhaojian Gong, Zhaoyang Zeng, Pranab Behari Mazumder, Jian Ma, Ming Zhou, Xiayu Li, Xiaoling Li, Wei Xiong, Yong Li, and Guiyuan Li -- Inflammation as a niche for tumor progression / Futoshi Okada -- Human papillomavirus and cervical cancer / Kurt J. Sales -- Hepatitis viruses and hepatocellular carcinoma / Wai-Kay Seto, Ching-Lung Lai, and Man-Fung Yuen -- Epstein-Barr virus and nasopharyngeal carcinoma / Xiaoying Zhou, Xue Xiao, Fu Chen, Tingting Huang, and Zhe Zhang -- Barrett's esophagus and esophageal cancer / Albert Roessner and Angela Poehlmann -- Asbestos-induced chronic inflammation and cancer / Andrea Napolitano, Sandro Jube, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, and Haining Yang -- Nanomaterials / Yiqun Mo, Rong Wan, David J. Tollerud, and Qunwei Zhang -- Inflammatory pathways of radiation-induced tissue injury / Danae A. Laskaratouu, Ifigeneia V. Mavragani, and Alexandros G. Georgakilas -- Photocarcinogenesis and inflammation / Chikako Nishigori -- Chemoprevention of colorectal cancer by anti-inflammatory agents / Michihiro Mutoh, Mami Takahasi, and Keiji Wakabayashi -- Nutraceuticals and colon cancer prevention / Deepak Poudyal and Lorne J. Hofseth -- Cancer chemoprevention by targeting cox-2 using dietary phytochemicals / Kyung-Soo Chun and Young-Joon Surh -- Regulation of inflammation-associated intestinal diseases with phytochemicals / Akira Murakami.
  • 2008 Springer
    A. Surbone, F. Peccatori, N. Pavlidis (eds.)
    Also available: Print – 2008
  • 2011 Springer
    editor, John P. Mulhall ; associate editors, Luca Incrocci, Irwin Goldstein and C. Rosen.
    Functional Anatomy of the Male Sex Organs -- Functional Anatomy of the Female Sex Organs -- Physiology of Libido -- Physiology of Orgasm -- Physiology of Female Genital Sexual Arousal -- Physiology of Erection -- Physiology of Ejaculation -- Classifying Female Sexual Dysfunction -- Hypoactive Sexual Desire Disorder -- Disorders of Female Sexual Arousal -- Disorders of Female Orgasm -- Sexual Pain Disorders -- Erectile Dysfunction: Prevalence and Pathophysiology -- Androgen Deficiency -- Peyronie?s Disease -- Disorders of Ejaculation and Male Orgasm -- Priapism -- The Sexual Health Interview: Male -- The Sexual Health Interview: Female -- Communication About Sexuality and Cancer -- Validated Questionnaires in Female Sexual Function Assessment -- Validated Questionnaires in Male Sexual Function Assessment -- Evaluation of the Female with Sexual Dysfunction -- Evaluation of Male Sexual Dysfunction -- The Impact of Cancer on the Partner?s Sexuality -- Gay and Lesbian Patients with Cancer -- The Impact of a Cancer Diagnosis on Sexual Health -- Breast Cancer -- Gynecological Cancers -- Pelvic Surgery for Urological Cancers -- Pelvic Radiation in Men -- Pelvic Radiation in Women -- Impact of Chemotherapy and Hormone Therapy on Female Sexual Health -- Impact of Androgen Deprivation Therapy on Men?s Sexual Health -- Colorectal Cancer -- Stem Cell Transplant --Sexual Health in the Terminally Ill -- Survivorship: An Overview -- Nutriceuticals in Sexual Health -- Medical Treatments for Sexual Problems in Women -- Surgical Treatments for Sexual Problems in Women -- Sex Therapy in Female Sexual Dysfunction -- Erectile Dysfunction: Pharmacological Therapy -- Erectile Dysfunction: Devices -- The Management of Premature Ejaculation -- Testosterone Therapy in the Male Cancer Patient -- Sex Therapy in Male Sexual Dysfunction -- Restoring Intimacy in Relationships Affected by Cancer -- Dating and Disclosure for Cancer Survivors.
  • 2002 NAP
    Samuel Wilson, Lovell Jones, Christine Coussens...[et al.], editors ; Roundtable on Environment Health Sciences, Research, and Medicine, Board on Health Science Policy, Institute of Medicine.
  • 2007 CRCnetBASE
    E.J. Hoffman.
  • 2016 Springer
    David M. Langenau, editor.
  • 2012 Springer
    Erle S. Robertson, editor.
    Peyton Rous: A Centennial Tribute to the Founding Father of Cancer Virology -- Viruses and Cancer: A Historical Perspective - HBV and Prevention of a Cancer -- Virus-Mediated Cell Proliferation -- Viral-Encoded Genes and Cancer -- Oncogenic Viruses and Cancer Transmission -- DNA Viruses and Cancer: Taking a Broader Look -- Herpesviruses and Cancer -- Lymphocryptoviruses: EBV and Its Role in Human Cancer -- Nonhuman Primate Gamma-herpesviruses and Their Role in Cancer -- Rhadinoviruses: KSHV and Associated Malignancies -- Retroperitoneal Fibromatosis Herpesvirus and Kaposi's Sarcoma-Like Tumors in Macaques -- Murine Gammaherpesvirus-Associated Tumorigenesis -- Marek's Disease Virus-Induced T-Cell Lymphomas -- Polyomaviruses and Cancer -- Polyomavirus SV40: Model Infectious Agent of Cancer -- BK Polyomavirus and Transformation -- Polyomavirus JC and Human Cancer: Possible Role of Stem Cells in Pathogenesis -- Merkel Cell Polyomavirus -- Human Papillomaviruses and Cancer -- Tumorigenesis by Adenovirus Type 12 E1A -- Overview of Hepatitis Viruses and Cancer -- Hepadnaviruses and Hepatocellular Carcinoma -- Hepatitis C Virus and Hepatocellular Carcinoma -- Human and Animal Retroviruses: HIV-1 Infection Is a Risk Factor for Malignancy -- HTLV-1 and Oncogenesis -- Human T-Cell Leukemia Virus Type 2 (HTLV-2) Biology and Pathogenesis -- Mechanisms of Oncogenesis by Avian and Murine Retroviruses -- Rous Sarcoma Virus: Contributions of a Chicken Virus to Tumor Biology, Human Cancer Therapeutics, and Retrovirology -- Mouse Mammary Tumor Virus and Cancer -- Jaagsiekte Sheep Retrovirus and Lung Cancer -- Small RNAs and Their Role in Herpesvirus-Mediated Cancers -- Viral Malignancies in HIV-Associated Immune Deficiency.
  • 2006
    edited by Sylvia Nagl.
    Status: Not Checked OutLane Catalog Record
    A path to knowledge : from data to complex systems models of cancer / Sylvia Nagl -- Theory of cancer robustness / Hiroaki Kitano -- Developing an integrated informatics platform for cancer research / Richard Begent -- Mathematical models of cancer / Manish Patel and Sylvia Nagl -- Some mathematical modelling challenges and approaches in cancer / Philip Maini and Robert A. Gatenby -- Computer simulation of tumour response to therapy / Georgios S. Stamatakos and Nikolaos Uzunoglu -- Structural bioinformatics in cancer / Stephen Neidle -- The mouse tumour biology database : an online resource for mouse models of human cancer / Carol J. Bult ... [et al.] -- Bioinformatics approaches to integrate cancer models and human cancer research / Cheryl L. Marks and Sue Dubman -- The FAPESP/LICR human cancer genome project : perspectives on integration / Ricardo Brentani ... [et al.]. Today's science, tomorrow's patient : the pivotal role of tissue, clinical data and informatics in modern drug development / Kirstine Knox, Amanda Taylor and David J. Kerr -- Software design ethics for biomedicine / Don Gotterbarn and Simon Rogerson -- Ethical issues of electronic patient data and informatics in clinical trial settings / Dipak Kalra and David Ingram -- Pharmacogenomics and cancer : ethical, legal and social issues / Mary Anderlik Majumder and Mark Rothstein.
  • 2014 Springer
    edited by Eric C. Schirmer, Jose I. de las Heras.
    Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology, but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis, and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers, and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer.
    Also available: Print – 2014
  • 2007
    Raymond W. Ruddon.
    Status: Not Checked OutLane Catalog Record
  • 2014 CRCnetBASE
    edited by Debmalya Barh, Angelo Carpi, Mukesh Verma, Mehmet Gunduz.
    "According to the American Cancer Society report, "by 2030, the global cancer burden is expected to nearly double, growing to 21.4 million cases and 13.2 million deaths." Early diagnosis improves treatment efficacy and quality of life as well as reduces the cost for disease management. However, the development of molecular markers for early cancer diagnosis is always a challenge. Some fundamental principles in medical practice are (a) primum non nocere, a Latin phrase that means "first, do no harm," and (b) even when a patient's prognosis is poor, the physician must do his or her best for improving quality of the patient's life. Therefore, noninvasive or minimally invasive cancer diagnostic methods are of choice that can avoid complications of biopsy and other unfavorable impacts on patient's health. In this context, patients' easily collectable biospecimens such as blood, serum, plasma, urine, stool, sputum, saliva, etc., based molecular markers having high specificity and sensitivity in early diagnosis are emerging rapidly and in many instances such markers are also emerging as next-generation prognostic indicators and personalized therapeutics and precision medicine. Several patents have been filed and/or granted on such markers, and a number of health-care companies and authorities currently use or focus on the development of such markers. The significance of clinical validation approaches of several markers has been discussed in different chapters. This book, Cancer Biomarkers: Noninvasive Early Diagnosis and Prognosis, reflects the rapid expansion of important scientific, technological, clinical, and translational aspects of noninvasive or minimally invasive molecular cancer biomarkers and their applications along with other conventional markers"-- Provided by publisher.
  • 2012 Springer
    Egidio Del Fabbro, Akio Inui, Florian Strasser ; contributors: David Blum, Hajime Suzuki.
  • 2013 Future Med
    editors, Josep M. Argilés, Silvia Busquets.
    Cancer cachexia / Josep M. Argilés & Sílvia Busquets -- Prevalence and clinical features of cancer cachexia / Neil Johns, Richard J.E. Skipworth, Kenneth C.H. Fearon & James A. Ross -- Pathogenesis of cancer cachexia / Fabio Penna, Francesco M. Baccino & Paola Costelli -- Current medications for cancer cachexia / Clelia Madeddu, Antonio Macciò, Maria Chiara Cau, Roberto Serpe & Giovanni Mantovani -- Latest developments in cachexia drug discovery : clinical trials / Josep M. Argilés, Francisco Javier López-Soriano, Britta Stemmler & Sílvia Busquets -- Comorbidities and prognosis / Alessandro Laviano, Gianluca Di Lazzaro Giraldi & Serena Rianda -- Index.
  • 2016 Springer
    Michael Silbermann, editor.
    Medical Care in Countries in Transition -- How to Prioritize Cancer Care for Countries in Transition -- Cancer Trends and Risk Factors in Morocco -- The Magic of Dreams: Conflicts and Quandaries Within Multicultural Societies in Transition -- Modeling Integrative Oncology for the Arab Population in Northern Israel -- Cancer Care in Palestine -- Influx of Foreign Refugees to Jordan and its Overall Burden on Cancer Care -- Caring For Children With Cancer In A Country Conflicted With Massive Refugee Migration: Jordan as an Example -- Challenges and Future Trends for Cancer Care in Egypt -- Cancer Care in Lebanon, New Trends and Challenges -- Cancer Care in an economically torn country: Cyprus -- Cancer Care in a Country Undergoing Transition: Turkey. Current Challenges and Trends for the Future -- Cancer Care in Sudan: Current Situation and Challenges -- Cancer care in Countries in Transition in Africa; the case of Uganda -- Cancer Care in Pakistan -- Cancer Care in India -- Cancer Care in Afghanistan -- Kazakhstan -- An overview of cancer care in societies in transition- Global perspectives: UAE Experience -- Cancer care in countries in transition: The Islamic Republic of Iran -- Cancer Care in Regions/Societies in Transition in the Gulf States: Sultanate of Oman -- Challenges and prospects in cancer care in Georgia -- Romania: Attempting to Catch up the European standards of care for cancer patients -- Recent challenges and achievements in cancer care in Latin American societies -- Caring for Refugees with Cancer: A Case for Training of US Oncology Professionals -- University of Texas MD Anderson Cancer Center Experience caring for patients from countries undergoing political-social conflict -- Forty Years Fast Forward: Vietnamese Refugees in the United States with Comments on their Cancer Care -- The current state of cancer care in North America -- Application of genetic testing for childhood cancers in emerging countries -- Cancer Care among Immigrants to North America -- Promoting Cancer Nursing Education, Training and Research in Countries in Transition.
  • 2014 CRCnetBASE
    edited by Satya Prakash Gupta.
    "Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles. The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including: Human T-cell leukemia virus type 1 (HTLV-1), Hepatitis C virus (HCV), Epstein-Barr virus (EBV), Human papilloma virus (HPV), Human herpes virus 8 (HHV-8)/Kaposi's sarcoma-associated herpes virus (KSHV), Human immunodeficiency virus (HIV/AIDS), Oncolytic viruses. This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies"--Provided by publisher.
  • 2011 Springer Protocols
    edited by Ian A. Cree.
    Xenotransplantation of breast cancers -- Feeder layers: Co-culture with nonneoplastic cells -- Drug design and testing: Profiling of antiproliferative agents for cancer therapy using a cell-based methyl-[3h]-thymidine incorporation assay -- Transfection and DNA-mediated gene transfer -- Analysis of drug interactions -- Development of rituximab-resistant B-NHL clones: An in vitro model for studying tumor resistance to monoclonal antibody-mediated immunotherapy -- Proteomic evaluation of cancer cells: Identification of cell surface proteins -- Measuring gene expression from cell cultures by quantitative reverse-transcriptase polymerase chain reaction -- Expression analysis of homeobox genes in leukemia/lymphoma cell lines -- Flow cytometric DNA analysis of human cancers and cell lines -- Angiogenesis assays -- Cell migration and invasion assays -- Molecular breakpoint analysis of chromosome translocations in cancer cell lines by long distance inverse-PCR -- Measurement of DNA damage in individual cells using the Single Cell Gel Electrophoresis (Comet) assay -- Purification of annexin V and its use in the detection of apoptotic cells -- Real-time cytotoxicity assays -- Differential staining cytotoxicity assay: A review -- Cell sensitivity assays: The ATP-based tumor chemosensitivity assay -- Cell sensitivity assays: The MTT assay -- Cellular chemosensitivity assays: An overview -- Isolation of endothelial cells from human tumors -- Isolation of inflammatory cells from human tumours -- Establishment and culture of leukemia-lymphoma cell lines -- Isolation and culture of ovarian cancer cells and cell lines -- Isolation and culture of squamous cell carcinoma lines -- Isolation and culture of melanoma and naevus cells and cell lines -- Isolation and culture of colon cancer cells and cell lines -- Generation of lung cancer cell line variants by drug selection or cloning -- Quality assurance and good laboratory practice -- Elimination of mycoplasmas from infected cell lines using antibiotics -- Detecting mycoplasma contamination in cell cultures by polymerase chain reaction -- Cell culture contamination -- Cytogenetic analysis of cancer cell lines -- Online verification of human cell line identity by STRDNA typing -- Characterization and authentication of cancer cell lines: An overview -- Storage of cell lines -- Principles of cancer cell culture -- Cancer biology.
  • v. 1-3, 1999-2000
    edited by John R.W. Masters and Bernhard Palsson.
    Status: Not Checked OutLane Catalog Record
  • 2014 Springer Protocols
    edited by Martha Robles-Flores, Universidad Nacional Autónoma de México, México D.F., México.
    Use of Biguanides to Improve Response to Chemotherapy -- Evaluating Response to Metformin/Cisplatin Combination in Cancer Cells Via Metabolic Measurement and Clonogenic Survival -- Quantifying the Autophagy-Triggering Effects of Drugs in Cell Spheroids with Live Fluorescence Microscopy -- Interdependency Between Genetic and Epigenetic Regulatory Defects in Cancer -- Experimental Strategies to Manipulate the Cellular Levels of the Multifunctional Factor CTCF -- Use of Serum-Circulating miRNA Profiling for the Identification of Breast Cancer Biomarkers -- Prostate Cancer Detection Using a Non-Invasive Method for Quantifying mi RNAs -- DNA Methylation Analysis of Steroid Hormone Receptor Genes -- Control of Oncogenic mi RNA Function by Light-Activated mi RNA Antagomirs -- Methods for the Study of Long Non-Coding RNA in Cancer Cell Signaling -- Microvesicles as Mediators of Intercellular Communication in Cancer -- In Vivo Rat Model to Study Horizontal Tumor Progression -- An In Vivo Model to Study the Effects of Tumoral Soluble Factors on the Vascular Permeability in Mice -- Use of the Tumor Repressor DEDD as a Prognostic Marker of Cancer Metastasis -- Zebrafish-Based Systems Pharmacology of Cancer Metastasis -- A Flow Cytometry-Based Assay for the Evaluation of Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC) in Cancer Cells -- Gene Disruption Using Zinc Finger Nuclease Technology.
  • 2014 CRCnetBASE
    edited by Kasirajan Ayyanathan, PhD.
  • 2013 Springer
    William C.S. Cho, editor.
    Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments' side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers. Throughout the past decade, the cancer chemopreventive potencies and treatment effects of a number of natural dietary agents present in different food sources have been evaluated by various experiments. Some of them have progressed to early clinical trials. This volume is a specialized book presenting the research evidence relevant to the use of specific diet therapy in cancer chemoprevention and treatment. We begin with lessons learned from dietary resveratrol as an effective agent with anticancer properties against malignancies, followed examples of flavonoids from fruits and vegetables in the prevention and treatment of cancer. Evidence for the beneficial influence of diet enriched with flax seed oil and green tea on cancer will be reviewed. Soy food intake may enhance the effects on anticancer treatment for breast cancer, whereas lycopene-rich foods may possess chemopreventive efficacy. There are also discussions on the contribution of the cancer preventive effects of the antioxidant-rich foods and Mediterranean diet. In addition, the modulation of proteasome pathways by nutraceuticals is highlighted. Finally, we close the book with a discussion on the attenuation of cell survival signaling by bioactive phytochemicals in the prevention and therapy cancer.
  • 2006 Ovid
    editors Bruce A. Chabner, Dan L. Longo.
    Clinical strategies for cancer treatment: the role of drugs / Bruce Chabner -- Preclinical aspects of cancer drug discovery and development / Paula Krosky ... [et al.] -- Pharmacokinetics / Jerry Collins, Jeffrey G. Supko -- Infertility after cancer chemotherapy / Angela Bradbury, Richard L. Schilsky -- Carcinogenesis of anticancer drugs / Laawrence S. Blaszkowsky, Charles Erlichman -- Antifolates / Brian P. Monahan, Carmen J. Allegra -- 5-Fluoropyrimidine / Jean L. Grem -- Cytidine analogues / David P. Ryan, Rocio Garcia-Carbonero, Bruce A. Chabner -- Purine antimetabolites / Kenneth R. Hande -- Hydroxyurea / Luis Paz-Ares, Ross C. Donehower, Bruce A. Chabner -- Antimicrotubule agents / Eric K. Rowinsky -- Clinical and high-dose alkylating agents / Kenneth D. Tew, O. Michael Colvin, Roy B. Jones -- Nonclassic agents / Henry S. Friedman, Steven D. Averbuch, Joanne Kurtzberg -- Cisplatin, Carboplatin, and oxaliplatin / Eddie Reed -- Bleomycin / John s. Lazo, Bruce A. Chabner -- Antitumor antibiotics / Edwin W. Willems, Kees Nooter, Jaap Verweij -- Topoisomerase I-targeting drugs / Alex Sparreboom, William C. Zamboni -- Anthracyclines and anthracenediones / James H. Doroshow -- Topoisomerase II inhibitors: the epipodophyllotoxins, acridines, and ellipticines / Yves Pommier, François Goldwasser -- Asparaginase / Bruce A. Chabner, Alison M. Friedmann -- Delivering anticancer drugs to brain tumors / Maciej M. Mrugala, Tracy T. Batchelor, Jeffrey G. Supko -- Food and drug administration role in oncology product development / Thomas G. Roberts Jr. -- Central venous catheters: care and complications / Rachel P. Rosovsky, David J. Kuter -- Pharmacogenetics / Jeanne Fourie, Robert B. Diasio -- New targets for anticancer therapeutics / A. Dimitrios Colevas ... [et al.] -- Bisphosphonates / Matthew R. Smith -- Thalidomide and its analogs for the treatment of hematologic malignancies, including multiple myeloma, and solid tumors / Paul Richardson ... [et al.] -- Inhibitors of tumor angiogenesis / Anaadriana Zakarija, William J. Gradishar -- Proteasome inhibitors / Owen A. O'Connor -- Molecular targeted drugs and growth factor receptor inhibitors / Jeffrey W. Clark -- Antibody therapies of cancer / David A. Scheinberg ... [et al.] -- Interferons / Daniel J. Lindner ... [et al.] -- Adoptive cellular therapies / Carl H. June -- Cancer vaccines / Glenn Dranoff -- Hematopoietic growth factors / William P. Petros -- Interleukins / Gheath Alatrash ... [et al.] -- Harmonal therapy for breast cancer / Peter F. Lebowitz, Sandra M. Swain.
  • 2011 Ovid
    [edited by] Bruce A. Chabner, Dan L. Longo.
    Clinical strategies for cancer treatment: the role of drugs -- Target identification and drug discovery -- Clinical drug development and marketing approval -- Principles of pharmacokinetics -- Delivering anticancer drugs to brain tumors -- Pharmacogenetics -- Physical barriers to drug delivery -- Antifolates -- 5-fluoropyrimidines -- Cytidine analogues -- Purine antimetabolites -- Hydroxyurea -- Antimitotic drugs -- Alkylating agents -- Platinum analogues -- Bleomycin and other antitumor antibiotics -- Topoisomerase I-targeting drugs -- Topoisomerase II inhibitors: anthracyclines -- Topoisomerase II inhibitors: the epipodophyllotoxins -- Asparaginase -- Proteasome inhibitors -- Histone deacetylase inhibitors in oncology -- Differentiating agents -- Arsenic trioxide -- Antibodies -- Inhibitors of tumor angiogenesis -- Epidermal growth factor receptor inhibitors -- HER2 inhibitors -- Molecular targeted drugs -- Signaling inhibitors: IGFR, PI3K pathway, embryonic signaling inhibitors, and mitotic kinase inhibitors -- Cytokine therapy for cancer -- Cancer vaccines -- Adoptive cellular therapies -- Thalidomide and its analogs in the treatment of hematologic malignancies, including multiple myeloma, and solid tumors -- Hormonal therapy of breast cancer -- Hormone therapy for prostate cancer -- Drug therapy of pain in cancer patients -- Hematopoietic growth factors -- Antinausea medications -- Bisphosphonates and other bone-targeted therapies -- Intravenous access and catheter management -- Late effects of cancer chemotherapy -- Infertility after cancer chemotherapy.
  • 2012 Springer
    Terry Priestman.
    A simple introduction explaining the broad principles underlying chemotherapy, this book gives trainees a framework within which they can place the specific aspects of cancer chemotherapy they encounter in their everyday experience. The first part of this book is unique in explaining the recent developments in the field in terms of their point of action in the natural history of cancer. The second and third sections contain a more straightforward description of practical aspects of chemotherapy, and the current place of drug treatment in everyday cancer management, including the outcomes of that treatment.
  • 2008 Springer
    Terry Priestman.
  • 2007 Springer
    edited by Stanley P.L. Leong.
    Historical perspective and evolving concerns for human research / Bernard Lo and Nesrin Garan -- Cancer trials and the Institutional Review Board (IRB) / Scott Kurtzman and Zita Lazzarini -- NCI's cancer therapy evaluation program: a commitment to treatment trials / Jeffrey S. Abrams, Anthony Murgo and Michaele C. Christian -- Practical guide for cancer clinical investigators / Steven Hirschfeld -- The role of cooperative groups in cancer clinical trials / Ann M. Mauer, Elizabeth S. Rich and Richard L. Schilsky -- The advocate role in clinical study development and partnering with patient advocates in your local institution / Barbara Parker -- The National Breast Cancer Coalition: setting the standard for advocate collaboration in clinical trials / Fran Visco -- The role of the principal investigator in cancer clinical trials / Stanley P.L. Leong -- The audit process and how to ensure a successful audit / Y. Nancy You, Lisa Jacobs, Elizabeth Martinez and David M. Ota -- The privacy rule (HIPAA) as it relates to clinical research / John M. Harrelson and John M. Falletta -- The Commission on Cancer, American College of Surgeons' response to HIPAA / E. Greer Gay -- Ethical and legal issues in the conduct of cancer clinical trials / Gerianne J. Sands and Peggy A. Means -- The role of the Office of Research Integrity in cancer clinical trials / Peter Abbrecht, Nancy Davidian, Samuel Merrill and Alan R. Price -- Strategies for the administration of a clinical trial infrastructure: lessons from a comprehensive cancer center / Leonard A. Zwelling and Carleen A Brunelli -- The clinical research process: building a system in harmony with its users / Greg Koski -- Cancer research and clinical trial in action: an important exercise before you embark on your study / Stanley P.L. Leong, Larry Carbone and Scott Kurtzman.
    Also available: Print – 2007
  • 2014 Wiley
    edited by Syed A. Abutalib, MD, Assistant Director, Hematology and Hematopoietic Cell Transplantation, Midwestern Regional Medical Center, Cancer Treatment Centers of America, Zion, IL, USA, USA, Maurie Markman, MD, Senior Vice President of Clinical Affairs, National Director of Medical Oncology, Center, Cancer Treatment Centers of America, Clinical Professor of Medicine, Drexel University College of Medicine, Philadelphia, PA, USA.
    Section 1 Malignant hematology and hematopoietic cell transplantation -- Part 1 Acute lymphoblastic leukemia in adults -- Part 2 Acute myeloid leukemia in adults -- Part 3 Myelodysplastic syndromes and related disorders -- Part 4 Myeloproliferative neoplasms -- Part 5 Chronic lymphocytic and other leukemias -- Part 6 Hodgkin Lymphoma -- Part 7 Non-Hodgkin's lymphomas -- Part 8 Plasma cell neoplasms and related disorders -- Part 9 Special issues in hematology -- Part 10 Special issues in hematopoietic cell transplantation -- Section 2 Oncology -- Part 1 Central nervous system tumors -- Part 2 Head and neck cancers and thoracic malignancies -- Part 3 Breast cancer -- Part 4 Gastrointestinal oncology -- Part 5 Genitourinary oncology -- Part 6 Skin malignancies -- Part 7 Gynecological malignancies -- Part 8 Sarcomas -- Part 9 Multidisciplinary approach: consultation with surgical oncology team -- Part 10 Multidisciplinary approach: consultation with radiation oncology team -- Part 11 Hereditary cancer syndromes and genetic testing in oncology -- Part 12 Special issues in hematology and oncology.
  • v. 1-6, 2006-08.
    World Health Organization.
    Status: Not Checked OutLane Catalog Record
    Module 1. Planning -- Module 2. Prevention -- Module 3. Early detection -- Module 4. Diagnosis and treatment -- Module 5. Palliative care -- Module 6. Policy and advocacy.
  • 2011 Springer Protocols
    by Lynda J. Campbell.
    [Publisher-supplied data] Cytogenetic studies of malignancy have become an essential tool in the clinical management of cancer patients. Cancer Cytogenetics: Methods and Protocols presents eminently practical key cytogenetic and FISH techniques for every stage of diagnostic service. Experts in the field describe detailed cytogenetic analysis methods, fluorescence in situ hybridization and array methods currently being applied to investigate and diagnose different varieties of cancer. Written in the highly successful Methods in Molecular Biology series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, and step-by-step, readily reproducible laboratory protocols. The authors of the various chapters have also provided extensive notes to guide individuals who are new to these methods through the pitfalls that bedevil all such testing. Authoritative and accessible, Cancer Cytogenetics: Methods and Protocols serves as an ideal guide to scientists of all backgrounds, allowing them to either establish new techniques in their laboratories or find the different variations of standard methods helpful in improving their results.
  • 2009
    edited by Sverre Heim, Felix Mitelman.
    Status: Not Checked OutLane Catalog Record
    A new approach to an old problem / Sverre Heim and Felix Mitelman -- Cytogenetic methods / David Gisselsson -- Cytogenetic nomenclature / Sverre Heim and Felix Mitelman -- Nonrandom chromosome abnormalities in cancer : an overview / Sverre Heim and Felix Mitelman -- Acute myeloid leukemia / Bertil Johansson and Christine J. Harrison -- Myelodysplastic syndromes / Harold J. Olney and Michelle M. Le Beau -- Chronic myeloid leukemia / Thoas Fioretos and Bertil Johansson -- Chronic myeloproliferative neoplasms / Peter Vandenberghe, Lucienne Michaux, and Anne Hagemeijer -- Acute lymphoblastic leukemia / Christine J. Harrison and Bertil Johansson -- Mature B- and T-cell neoplasms and Hodgkin lymphoma / Reiner Siebert -- Tumors of the upper aerodigestive tract / Mihaela Avramut and Susanne M. Gollin -- Tumors of the lung / Penny Nymark, Eeva Kettunen, and Sakari Knuutila -- Tumors of the digestive tract / Georgia Bardi and Sverre Heim -- Tumors of the urinary tract / Paola Dal Cin and Azra H. Ligon -- Tumors of the breast / Manuel R. Teixeira, Nikos Pandis, and Sverre Heim -- Tumors of the female genital organs / Francesca Micci and Sverre Heim -- Tumors of the male genital organs / Manuel R. Teixeira and Sverre Heim -- Tumors of endocrine glands / Jörn Bullerdiek and David Gisselsson -- Tumors of the nervous system / Aaron M. Bender ... [et al.] -- Tumors of the eye / Karen Sisley -- Tumors of the skin / Fredrik Mertens and Sverre Heim -- Tumors of bone / Fredrik Mertens and Nils Mandahl -- Soft tissue tumors / Nils Mandahl and Fredrik Mertens.
  • 2006 Springer
    edited by Beverly A. Teicher.
    Also available: Print – 2006
  • 2008 Springer
    [edited by] Stéphane Culine et Jean-Jacques Patard.
  • 2009 Springer
    de Dominique Gros.
  • v. 1-2, 2009 Springer Protocols
    v. 2, 2009 Springer Protocols
    edited by Mukesh Verma.
    v. 1. Host susceptibility factors -- v. 2. Modifiable factors.
  • 2006
    edited by David Schottenfeld, Joseph F. Fraumeni, Jr. ; associate editors, Graham A. Colditz, Jonathan M. Samet, Alice S. Whittemore.
    Status: Not Checked OutLane Catalog Record
  • 2009 CRCnetBASE
    edited by Trygve Tollefsbol.
    The role of epigenetics in cancer / Trygve O. Tollefsbol -- DNA hypomethylation in cancer / Peter L. Molloy -- DNA hypermethylation in oncogenesis / J. Tyson DeAngelis ... [et al.] -- Imprinting alterations in tumorigenesis / Jeremiah Bernier-Latmani and Phillip Shaw -- Proteins that modulate DNA methylation aberrations in cancer / Sabrina L. Walthall ... [et al.] -- The role of DNA methylation in cancer progression / Sang-Woon Choi and Simonetta Friso -- Alterations in histone acetylation in tumorigenesis / Sabita N. Saldanha and Trygve O. Tollefsbol -- Histone methylation and the initiation of cancer / Shi Huang -- The role of sirtuins in aging and tumorigenesis / Xiaohong Zhang ... [et al.] -- Proteins that alter histone modifications in cancer / Ada Ao and Jianrong Lu -- Dietary and environmental influences on histone modifications in cancer / Sabita N. Saldanha ... [et al.] -- Noncoding RNAs in cancer / Maciej Szymanski and Jan Barciszewski -- Cancer-linked DNA hyper- and hypomethylation: chromosome positional effects / Melanie Ehrlich -- Chromatin remodeling and cancer / Sari Pennings and Richard R. Meehan -- Poly-ADP-ribosylation in cancer / Rajeshwar N. Sharan -- Polycomb group proteins in tumorigenesis / Hanneke E.C. Niessen and Jan Willem Voncken -- Cancer and aging: the epigenetic connection / Craig A. Cooney -- DNA methylation in tumor diagnosis / Kavitha Ramachandran, Edna Gordian, and Rakesh Singal -- DNA methylation profiles as prognostic markers for cancer / Sam Thiagalingam and Panagiotis Papageorgis -- Diagnosing cancer using histone modification analysis / Mukesh Verma and Deepak Kumar -- Histone modifications in cancer biology and prognosis / Matthew A. McBrian, David B. Seligson, and Siavash K. Kurdistani -- Histone deacetylase inhibitors in cancer therapy / Aaron M. Sargeant ... [et al.] -- Methylation changes in neoplasia: diagnostic and therapeutic implications / Eleftheria Hatzimichael, Justin Stebbing, and Tim Crook -- Clinical trials and approved drugs for epigenetic cancer therapy / Debby M.E.I. Hellebrekers and Manon van Engeland -- Future directions in epigenetic cancer research / Jacob Peedicayil.
    Also available: Print – 2009
  • 2012 Springer Protocols
    edited by Ramona G. Dumitrescu, Mukesh Verma.
    Epigenetic markers of early tumor development / Ramona G. Dumitrescu -- Epigenetics of solid cancer stem cells / Alok Mishra and Mukesh Verma -- DNA methylation and histone modifications in breast cancer / Ramona G. Dumitrescu -- DNA methylation changes in prostate cancer / Wolfgang Goering, Michael Kloth, and Wolfgang A. Schulz -- DNA methylation in promoter region as biomarkers in prostate cancer / Mihi Yang and Jong Y. Park -- Epigenetics of bladder cancer / Wun-Jae Kim and Yong-June Kim -- Epigenetics in myeloid malignancies / Stefan Deneberg -- The epigenetics of brain tumors / Adrian M. Dubuc [and others] -- DNA methylation changes in cervical cancers / Qiang Lu, Dehua Ma, and Shuping Zhao -- Epigenetics of colon cancer / Sharad Khare and Mukesh Verma -- Promoter methylation in head and neck tumorigenesis / Jesena K. Stephen [and others] -- Epigenome and DNA methylation in oral squamous cell carcinoma / Mario Pérez-Sayáns García and Abel García-García -- Clinical implications of epigenetic alterations in human thoracic malignancies : epigenetic alterations in lung cancer / Keiko Shinjo and Yutaka Kondo -- The role of microRNAs in the management of liver cancer / Krishna K. Banaudha and Mukesh Verma -- Epigenetics in ovarian cancer / L.M.S. Seeber and P.J. van Diest -- DNA methylation in pancreatic cancer : protocols for the isolation of DNA and bisulfite modification / Katja Biewusch [and others] -- Detection and analysis of DNA methylation by pyrosequencing / Hilary A.A. Colyer [and others] -- Screening for miRNA expression changes using quantitative PCR (Q-PCR) / Richard N. Armstrong, Hilary A.A. Colyer, and Ken I. Mills -- Genome-wide methylation analysis / Alexander Unterberger, Adrian M. Dubuc, and Michael D. Taylor -- Microarray for epigenetic changes : gene expression arrays / Hilary A.A. Colyer, Richard N. Armstrong, and Ken I. Mills -- Detecting DNA methylation using the methylated CpG island amplification and microarray technique / Hilary A.A. Colyer, Margaret Dellett, and Ken I. Mills -- Nutrigenomics : implications for breast and colon cancer prevention / Gabriela Riscuta and Ramona G. Dumitrescu -- Dietary and lifestyle factors of DNA methylation / Unhee Lim and Min-Ae Song -- Diet, epigenetics, and cancer / L. Joseph Su -- Role of epigenetics in cancer health disparities / Sulma I. Mohammed, Sanya Springfield, and Rina Das -- Multifactorial etiology of gastric cancer / Jovanny Zabaleta -- Epigenetic epidemiology for cancer risk : harnessing germline epigenetic variation / Kevin Brennan and James M. Flanagan -- Epigenetic biomarkers in cancer epidemiology / Mukesh Verma.
  • 2015 Springer Protocols
    edited by Mukesh Verma.
    Cancer epigenetics : an introduction / Rajnee Kanwal, Karishma Gupta, and Sanjay Gupta -- Community resources and technologies developed through the NIH roadmap epigenomics program / John S. Satterlee ... [et al.] -- Epigenome-wide association studies (EWAS) : past, present, and future / James M. Flanagan -- Epigenetic biomarkers in liver cancer / Krishna K. Banaudha and Mukesh Verma -- Cancer type-specific epigenetic changes : gastric cancer / Danielle Queiroz Calcagno, Marília de Arruda Cardoso Smith, and Rommel Rodriguez Burbano -- Beyond the island : epigenetic biomarkers of colorectal and prostate cancer / Andrea J. Savio and Bharati Bapat -- Prostate cancer epigenome / Swathi Chinaranagari ... [et al.] -- CpG island hypermethylation as a biomarker for the early detection of lung cancer / Yujin Kim and Duk-Hwan Kim -- Analysis of DNA methylation in pancreatic cancer : an update / Christian Pilarsky and Robert Grützmann -- Epigenetics of urothelial carcinoma / Wolfgang A. Schulz ... [et al.] -- Epigenetics of prostate cancer / Tawnya C. McKee and James V. Tricoli -- Methylation profile landscape in mesothelioma : possible implications in early detection, disease progression, and therapeutic options / Xinbo Zhang ... [et al.] -- Techniques to access histone modifications and variants in cancer / Monica Tyagi ... [et al] -- Single base resolution analysis of 5-methylcytosine and 5-hydroxymethylcytosine by RRBS and TAB-RRBS / Maria A. Hahn ... [et al.] -- Quantitative DNA methylation analysis for epigenotyping of colorectal cancer / Atsushi Kaneda and Koichi Yagi -- Histone modifications associated with cancer cell migration and invasion / Miki Hieda, Nariaki Matsuura , and Hiroshi Kimura -- Aberrant epigenetic modifications in radiation-resistant head and neck cancers / Hon-Yi Lin, Tim Hui-Ming Huang, and Michael Wing-Yan Chan -- Cancer-associated infectious agents and epigenetic regulation / Vidya Vedham and Mukesh Verma -- Toxicoepigenomics and cancer : implications for screening / Mukesh Verma -- Human papilloma virus (HPV) modulation of the HNSCC epigenome / Josena K. Stephen and Maria J. Worsham -- Epigenetic regulation of HIV, AIDS, and AIDS-related malignancies / Mukesh Verma -- Epigenetics of colorectal cancer / Wenji Yan and Mingzhou Guo -- Epigenetics in breast and prostate cancer / Yanyuan Wu, Marianna Sarkissyan, and Jaydutt V. Vadgama -- Epigenetic inhibitors / Mukesh Verma and Hirendra Nath Banerjee -- Use of epigenetic modulators as a powerful adjuvant for breast cancer therapies / Aurore Claude-Taupin ... [et al.] -- Epigenetic approaches in glioblastoma multiforme and their implication in screening and diagnosis / Gwyneth Hyman ... [et al.] -- Detection of circulatory microRNAs in prostate cancer/ Anvesha Srivastava ... [et al.] -- Identification and characterization of small-molecule inhibitors of lysine acetyltransferases / Daiqing Liao -- Epigenetic regulation in biopsychosocial pathways / Kristin Litzelman and Mukesh Verma -- Viral epigenetics / Barry I. Milavetz and Lata Balakrishnan -- P53 tumor suppression network in cancer epigenetics / Alok Mishra, Daniel J. Brat, and Mukesh Verma -- Promoter hypermethylation as a biomarker in prostate adenocarcinoma / Jong Y. Park -- Sequencing the cancer methylome / Austin Y. Shull ... [et al.] -- Global DNA methylation profiling technologies and the ovarian cancer methylome / Jessica Tang ... [et al.] -- Recent progress in the discovery of epigenetic inhibitors for the treatment of cancer / Sharad K. Verma -- At the crossroad between obesity and gastric cancer / Jone Garai ... [et al.] -- Detection of epigenetic aberrations in the development of hepatocellular carcinoma / Yujing Zhang -- Specific type epigenetic changes in cervical cancers / Shuping Zhao -- Epigenetics in head and neck cancer / Syeda Marriam Bakhtiar, Amjad Ali, and Debmalya Barh -- Epigenetic therapy for colorectal cancer / Vivek Vaish ... [et al.] -- Epigenetics of gastric cancer / Mingzhou Guo and Wenji Yan.
  • 2013
    Craig Patrick Giacomini.
    Recurrent gene fusions and chromosomal translocations have long been recognized for their roles in oncogenesis. This dissertation employs genomic approaches to discover and characterize novel gene fusions in several cancer types. First we developed a "breakpoint analysis" pipeline for gene fusion discovery and applied this method to a collection of nearly 1,000 human cancer samples profiled on DNA microarrays. This approach led to the discovery and characterization of twelve new gene fusions in diverse cancer types including angiosarcoma, pancreatic cancer, and colon cancer. Separately, we performed RNA Sequencing on a series of 36 breast cancer specimens and used a suite of computational tools developed in-house to discover ~350 candidate gene rearrangements. Notably, we discovered recurrent fusions of the sterile 20 (STE20)-like kinase TAOK1, and functional studies suggest that these fusions encode potent oncoproteins that drive breast carcinogenesis. Many of the alterations discovered in this dissertation represent the first gene fusions reported to date in the corresponding cancer type, and many represent potentially druggable targets with therapeutic implications for patients.
  • 2005 Springer
    edited by David T. Curiel, Joanne T. Douglas.
    Cancer gene therapy : historical perspective / Malcolm K. Brenner -- The genetic basis of cancer / Akseli Hemminki and Kari Hemminki -- Tumor suppressor gene replacement for cancer / Jack A. Roth and Susan F. Grammer -- Antisense technology / Ruiwen Zhang and Hui Wang -- Cancer therapeutic applications of ribozymes and RNAi / Lisa Scherer and John J. Rossi -- Fusogeneic membrane glycoproteins for cancer gene therapy : a better class of killer / Andrew Bateman ... [et al.] -- Suicide gene therapy / Caroline J. Springer and Ion Niculescu-Duvaz -- Molecular chemotherapy approaches / Daniel H. Palmer and David J. Kerr -- Genetic immunotherapy approaches / Denise R. Shaw and Albert F. LoBuglio -- Immunotherapy of cancer by dendritic cell-targeted : gene transfer / Tanja D. de Gruijl, Herbert M. Pinedo, and Rik J. Scheper -- Dendritic cells / Weiping Zou, Shuang Wei and Tyler J. Curiel -- Polynucleotide immunization for cancer therapy / Theresa V. Strong -- Development of oncolytic replication-competent herpes simplex virus vectors: the G207 paradigm / Tomoki Todo and Samuel D. Rabkin -- Development of oncolytic adenoviruses : from the lab bench to the bedside / John A. Howe, Robert Ralston, and Murali Ramachandra -- Conditionally replicating adenoviruses for cancer treatment / Ramon Alemany -- Reovirus as an oncolytic agent / Megan K. Patrick, Kara L. Norman, and Patrick W. K. Lee -- Antiangiogenic gene therapy of cancer / Steve Gyorffy ... [et al.] -- Proapoptotic strategy in cancer gene therapy / David H. Holman ... [et al.] -- Antimetastasis / Duen-Hwa Yan, Kung-Ming Rau, and Mien-Chie Hung -- Antimetastatic gene therapy : prostate cancer theory to therapy / Thomas A. Gardner ... [et al.] -- Drug-resistance gene transfer as an antitumor strategy / Colin L. Sweeney and R. Scott McIvor -- Chemosensitization / Per Eystein Lønning -- Radiosensitization by gene therapy / Steven J. Chmura, Michael Garofalo, and Ralph R. Weichselbaum -- Nonviral vector systems for cancer gene therapy / Greg F. Walker and Ernst Wagner -- Viral vectors for cancer gene therapy / Joanne T. Douglas and David T. Curiel -- Bacterial systems for tumor-specific gene therapy / J. Martin Brown ... [et al.] -- Molecular imaging of cancer gene therapy / Harvey R. Herschman -- Cancer-related gene therapy clinical trials / Robert J. Korst and Ronald G. Crystal -- Regulatory aspects in the development of gene therapies / Rosemarie Aurigemma ... [et al.].
  • 2010 Springer
    Boris Pasche, editor.
    Also available: Print – 2010
  • 2010 Springer
    Andrei Thomas-Tikhonenko, editor.
  • 2014 ScienceDirect
    edited by Graham Dellaire, Jason N. Berman, Robert J. Arceci.
    Cancer Genomics addresses how recent technological advances in genomics are shaping how we diagnose and treat cancer. Built on the historical context of cancer genetics over the past 30 years, the book provides a snapshot of the current issues and state-of-the-art technologies used in cancer genomics. Subsequent chapters highlight how these approaches have informed our understanding of hereditary cancer syndromes and the diagnosis, treatment and outcome in a variety of adult and pediatric solid tumors and hematologic malignancies. The dramatic increase in cancer genomics research and ever-increasing availability of genomic testing are not without significant ethical issues, which are addressed in the context of the return of research results and the legal considerations underlying the commercialization of genomic discoveries. Finally, the book concludes with "Future Directions", examining the next great challenges to face the field of cancer genomics, namely the contribution of non-coding RNAs to disease pathogenesis and the interaction of the human genome with the environment. Tools such as sidebars, key concept summaries, a glossary, and acronym and abbreviation definitions make this book highly accessible to researchers from several fields associated with cancer genomics.Contributions from thought leaders provide valuable historical perspective to relate the advances in the field to current technologies and literature.
  • 2013 Springer
    Ulrich Pfeffer, editor.
    Genomic Pathology of Lung Cancer / Kenneth J. Craddock, Shirley Tam, Chang-Qi Zhu, Ming-Sound Tsao -- Understanding Melanoma Progression by Gene Expression Signatures / J. Tímár, T. Barbai, B. Győrffy, E. Rásó -- Prognostic Testing in Uveal Melanoma / Michael Zeschnigk, Dietmar R. Lohmann -- Capturing and Deciphering the Molecular Signatures of Head and Neck Cancer / Thomas J. Belbin, Roberto A. Lleras, Richard V. Smith -- Predictive and Prognostic Biomarkers for Colorectal Cancer / Lara Lipton, Michael Christie, Oliver Sieber -- Expression Profiling of Hepatocellular Carcinoma / Rosina Maria Critelli, Elisabetta Cariani, Erica Villa -- Kidney Cancer Genomics: Paving the Road to a New Paradigm of Personalized Medicine / George M. Yousef, Nicole M. A. White, Andrew H. Girgis -- Pancreatic Cancer Genomics / Vincenzo Corbo, Andrea Mafficini, Eliana Amato, Aldo Scarpa -- Breast Cancer Genomics: From Portraits to Landscapes / Ulrich Pfeffer, Valentina Mirisola, Alessia Isabella Esposito -- Genomic Landscape of Ovarian Cancer / Delia Mezzanzanica, Loris De Cecco, Marina Bagnoli, Patrizia Pinciroli -- Genetics of Endometrial Carcinoma / M. Angeles López-García, Begoña Vieites, M. Angeles Castilla -- Usefulness of Molecular Biology in Follicular-Derived Thyroid Tumors: From Translational Research to Clinical Practice / Alexandre Bozec, Marius Ilie, Paul Hofman -- Sarcomas Genetics: From Point Mutation to Complex Karyotype, from Diagnosis to Therapies / Frédéric Chibon, Alain Aurias, Jean-Michel Coindre -- Novel Molecular Acquisitions in Leukemias / Sabina Chiaretti, Robin Foà -- Where Do We Stand in the Genomics of Lymphomas? / Francesco Bertoni, Zhi-Ming Li, Emanuele Zucca -- The Genomics of Multiple Myeloma and Its Relevance in the Molecular Classification and Risk Stratification of the Disease / Antonino Neri, Luca Agnelli -- Genome-Wide Analysis and Gene Expression Profiling of Neuroblastoma: What Contribution Did They Give to the Tumor Treatment? / Gian Paolo Tonini.
  • 2014 Springer Protocols
    edited by Narendra Wajapeyee.
    Genome-Wide Mapping Of RNA Pol-II Promoter Usage In Mouse Tissues By Chip-Seq -- Using Native Chromatin Immunoprecipitation To Interrogate Histone Variant Protein Deposition In Embryonic Stem Cells -- Reduced Representation Bisulfite Sequencing To Identify Global Alteration In The DNA Methylation -- A High-Throughput Microrna Expression Profiling System -- Using Pooled Mir30-Shrna Library For Cancer Lethal And Synthetic Lethal Screens -- Genome-Wide RNA Interference Screening To Identify Regulators Of Epigenetic Silencing Of A Tumor Suppressor Gene -- A Diphtheria Toxin Negative Selection In RNA Interference Screening -- Cancer Metabolism: Crosstalk Between Signaling And O-Glcnacylation -- Targeted Genome Modification Via Triple Helix Formation -- Synthesis Of Stabilized Alpha-Helical Peptides -- Arginine-Grafted Biodegradable Polymer: A Versatile Transfection Reagent For Both DNA And Sirna -- Using Laco Arrays To Monitor DNA Double-Strand Break Dynamics In Live Schizosaccharomyces Pombe Cells -- Zebrafish As A Platform To Study Tumor Progression -- Clonal Screens To Find Modifiers Of Partially Penetrant Phenotypes In C. Elegans -- Serum Profiling Using Protein Microarrays To Identify Disease Related Antigens -- Interrogation Of In Vivo Protein-Protein Interactions Using Transgenic Mouse Models And Stable Isotope Labeling -- New Biophysical Methods To Study The Membrane Activity Of Bcl-2 Proteins -- Purification Of Recombinant 2XMBP Tagged Human Proteins From Human Cells -- Computational Analysis In Cancer Exome Sequencing -- Matrix Factorization Methods For Integrative Cancer Genomics -- Computational Methods For DNA Copy-Number Analysis Of Tumors.
  • 2007 Springer Protocols
    edited by Paul B. Fisher.
    Reciprocal subtraction differential RNA display (RSDD) : an efficient technology for cloning differentially expressed genes / Devanand Sarkar, Dong-chul Kang, and Paul B. Fisher -- Cloning differentially expressed genes using rapid subtraction hybridization (RaSH) / Habib Boukerche ... [et al.] -- The application of differential display as a gene profiling tool / Ken Chien-Neng Chang ... [et al.] -- Serial analysis of gene expression (SAGE) / Fred van Ruissen and Frank Baas -- Gene expression profile analysis of tumors / Katia Basso and Riccardo Dalla-Favera -- cDNA microarray and bioinformatic analysis of nuclear factor [kappa]B related genes in squamous cell carcinoma / Zhong Chen ... [et al.] -- Gene profiling uncovers retinoid target genes / Yan Ma ... [et al.] -- Complete open reading frame (C-ORF) technique : rapid and efficient method for obtaining complete protein coding sequences / Dong-chul Kang and Paul B. Fisher -- Chromatin immunoprecipitation assays : molecular analysis of chromatin modification and gene regulation / Piyali Dasgupta and Srikumar P. Chellappan -- Manipulating genes and gene copy number by bacterial artificial chromosome transfection / Stephanie F. Phelps, Sharon Illenye, and Nicholas H. Heintz -- Molecular cytogenetic applications in analysis of the cancer genome / Pulivarthi H. Rao, Subhadra V. Nandula, and Vundavalli V. Murty -- Monitoring methylation and gene expression in cancer / Hetty Carraway and James Herman -- The use of phage display peptide libraries for basic and translational research / Renee Brissette and Neil I. Goldstein -- Yeast and mammalian two-hybrid systems for studying protein-protein interactions / Shu-ichi Matsuzawa and John C. Reed -- Ribonomic and short hairpin RNA gene silencing methods to explore functional gene programs associated with tumor growth arrest / Timothy E. Baroni ... [et al.] -- Surface-epitope masking (SEM) : an immunological subtraction approach for developing monoclonal antibodies targeting surface-expressed molecules / Neil I. Goldstein and Paul B. Fisher -- Approaches for monitoring signal transduction changes in normal and cancer cells / Paul Dent ... [et al.] -- PKR in innate immunity, cancer, and viral oncolysis / Siddharth Balachandran and Glen N. Barber -- Analysis of transformation and tumorigenicity using mouse embryonic fibroblast cells / Hong Sun and Reshma Taneja -- Analysis of growth properties and cell cycle regulation using mouse embryonic fibroblast cells / Hong Sun, Neriman Tuba Gulbagci, and Reshma Taneja -- Reverse phase protein microarrays for monitoring biological responses / Virginia Espina ... [et al.] -- Protein crystallization / Champion Deivanayagam, William J. Cook, and Mark R. Walter.
  • 2007 Springer
    edited by Ivan Damjanov, Fang Fan.
  • 2013 Springer
    Ivan Damjanov, Fang Fan, editors.
    This is the second edition of a practice-oriented, well-illustrated manual on the microscopic grading of tumors. After an introduction on the history and basic tenets of tumor grading, subsequent chapters focus on specific organ systems. In each case, the most widely used system for grading common tumors is presented and discussed. Throughout, careful attention is paid to the principles of microscopic tumor grading, ancillary methods to improve grading, and the latest techniques used in evaluating tumors and formulating prognosis.
  • 2015 Springer
    Nima Rezaei, editor.
    Specific Organ Tumors: General Considerations On Immunotherapy -- Vaccination Of Human Solid Tumors: Recent Progress In The Clinical Setting -- Immunotherapy For Pediatric Solid Tumors -- Immunopathology Of Hematological Cancers And Immunotherapy Of Leukemia And Multiple Myeloma -- Immunopathology Of Lymphoma And Immunotherapy Of Hodgkin's Disease And Non-Hodgkin's Lymphoma -- Cancer-Testis Antigens As Targets For The Immunotherapy Of Hematological Malignancies -- Tumor Immunology And Immunotherapy Of Gastrointestinal Tract Cancers -- Immunology And Immunotherapy Of Colorectal Cancer -- Immunopathology Of Hepatobiliary Tumors And Immunotherapy Of Liver Cancers -- Immunology And Immunotherapy Of Pancreatic Tumors -- Immunology Of Cutaneous Tumors And Immunotherapy For Melanoma -- Immunopathology Of Head And Neck Tumors And Immunotherapy Of Squamous Cell Carcinoma -- Immunopathology And Immunotherapy Of Oral Cancers -- Immunopathology Of Bone And Connective Tissue Cancers And Immunotherapy Of Sarcomas -- Immunopathology Of Central Nervous System Cancers And Immunotherapy Of Brain Tumors -- Immunology And Immunotherapy Of Pulmonary Tumors -- Immunopathology Of Urinary System Cancers And Immunotherapy Of Renal And Bladder Cancers -- Immunopathology Of Cancers Of Male And Female Genitalia Organs And Immunotherapy Of Cervical And Prostate Cancer -- Immunology And Immunotherapy Of Ovarian Cancer -- Revisiting Immunology For Breast Cancer -- Immunology And Immunotherapy Of Graft Versus Host Disease.
  • 2015 Springer
    Nima Rezaei, editor.
    Cancer Immunology is intended as an up-to-date, clinically relevant review of cancer immunology and immunotherapy. The rapid flow of studies in the field of cancer immunology during the last decade has increased our understanding of the interactions between the immune system and cancerous cells. In particular, it is now well known that such interactions result in the induction of epigenetic changes in cancerous cells and the selection of less immunogenic clones as well as alterations in immune responses. Understanding the cross-talk between nascent transformed cells and cells of the immune system has led to the development of combinatorial immunotherapeutic strategies to combat cancer. This volume is focused on interactions between cancerous cells and various components of the innate and adaptive immune system are fully described. Notably, the principal focus is very much on clinical aspects, the aim being to educate clinicians on the clinical implications of the most recent findings and novel developments in the field. This is to be hoped that this translational book will be comprehensible, cogent and of special value for researchers and clinicians who wish to extend their knowledge on cancer immunology.
  • 2011 Springer
    Glenn Dranoff, Editor.
    Immune infiltration in human cancer : prognostic significance and disease control / Wolf H. Fridman ... [et al.] -- Subversion and coercion : the art of redirecting tumor immune surveillance / John B. Mumm and Martin Oft -- STAT3 : a target to enhance antitumor immune response / Heehyoung Lee ... [et al.] -- Biology and clinical observations of regulatory T cells in cancer immunology / Michele W. Teng ... [et al.] -- Concepts and ways to amplify the antitumor immune response / Bent Rubin and Jean Edouard Gairin -- Angiogenesis and the tumor vasculature as antitumor immune modulators : the role of vascular endothelial growth factor and endothelin / Lana E. Kandalaft ... [et al.] -- Adoptive cellular therapy / Stephen A. Grupp and Carl H. June -- Dendritic cell subsets as vectors and targets for improved cancer therapy / Karolina Palucka ... [et al.] -- Identification of human idiotype-specific T cells in lymphoma and myeloma / Jinsheng Weng ... [et al.] -- Modulation of CTLA-4 and GITR for Cancer Immunotherapy / Francesca Avogadri ... [et al.] -- Immunobiology of cancer therapies targeting CD137 and B7-H1/PD-1 cosignal pathways / Shengdian Wang and Lieping Chen -- LAG-3 in cancer immunotherapy / Monica V. Goldberg and Charles G. Drake -- Immunologically active biomaterials for cancer therapy / Omar A. Ali and David J. Mooney -- Erratum : Identification of human idiotype-specific T cells in lymphoma and myeloma / Jinsheng Weng ... [et al.].
    Also available: Print – 2011
  • 2015 Springer
    Nima Rezaei, editor.
    This translational book describes in detail the clinical application of novel approaches in cancer immunotherapy with the aim of educating clinicians in the implications of the most recent research and new developments in the field. The scope is broad, encompassing, for example, prognostic biomarkers for personalized cancer treatment, strategies for targeting tumor immunosuppression, gene therapy, virus-based vaccines, targeting of cancer stem cells, hematopoietic stem cell transplantation, the role of T lymphocytes in cancer immunotherapy, use of monoclonal antibodies, and many more innovative approaches. Clinical immunologists, hematologists, and oncologists in particular will find the book to be of value in expanding their knowledge. ℗ℓ The book is the second in a three-volume series, Cancer Immunology, which offers an up-to-date review of cancer immunology and immunotherapy. The remaining volumes focus on the immunopathology of cancers and cancer immunotherapy for organ-specific tumors. In total the series, designed for both clinicians and researchers, includes contributions from more than 250 scientists working at leading universities and institutes from across the world.
  • 2007
    edited by George Prendergast, Elizabeth M. Jaffee.
    Immunotherapy and cancer therapeutics : why partner? / Leisha A. Emens and Elizabeth M. Jaffee -- Immune stimulatory features of classical chemotherapy / Robbert G. van der Most, Anna K. Nowak, and Richard A. Lake -- Dendritic cells and coregulatory signals : immune checkpoint blockade to stimulate immunotherapy / Drew Pardoll -- Regulatory T cells in tumor immunity : role of toll-like receptors / Rong-Fu Wang -- Tumor-associated macrophages in cancer growth and progression / Alberto Mantovani, Paola Allavena, and Antonio Sica -- Tumor-associated myeloid-derived suppressor cells / Stephanie K. Bunt ... [et al.] -- Programmed death ligand-1 and galectin-1 : pieces in the puzzle of tumor-immune escape / Gabriel A. Rabinovich and Thomas F. Gajewski -- Indoleamine 2,3-dioxygenase in immune escape : regulation and therapeutic inhibition / Alexander J. Muller and George C. Prendergast -- Arginase, nitric oxide synthase, and novel inhibitors of L-arginine metabolism in immune modulation / Susanna Mandruzzato, Simone Mocellin, and Vincenzo Bronte. Introduction / George C. Prendergast and Elizabeth M. Jaffee -- Cancer immunoediting : from immune surveillance to immune escape / Ryungsa Kim -- Immunosurveillance : innate and adaptive antitumor immunity / Masahisa Jinushi and Glenn Dranoff -- Cytokine regulation of immune tolerance to tumors / Ming O. Li and Richard A. Flavell -- Immunological sculpting : natural killer cell receptors and ligands / David A. Sallman and Julie Y. Djeu -- Immune escape : immunosuppressive networks / Shuang Wei, Alfred Chang, and Weiping Zou -- Cytotoxic chemotherapy in clinical treatment of cancer / Rajesh Thirumaran, George C. Prendergast, and Paul B. Gilman -- Targeted therapeutics in cancer treatment / Colin D. Weekes and Manuel Hidalgo -- Concepts in pharmacology and toxicology / Richard A. Westhouse and Bruce D. Car -- Cancer immunotherapy : challenges and opportunities / Andrew J. Lepisto, John R. McKolanis, and Olivera J. Finn -- Cancer vaccines / Freda K. Stevenson ... [et al.] --
  • 2013 Springer
    Tyler J. Curiel, editor.
    This volume is a comprehensive discussion of the major factors affecting tumor immunology and a discussion of all major anti-cancer immunotherapeutic agents approved by the Food and Drug Administration of the United States and by European agencies. Many promising but unapproved agents in clinical trials are also discussed, as are key pre-clinical developments. The major challenges and intellectual issues facing investigators developing novel immunotherapeutics are discussed in detail as are conceptual developments influencing current and future treatment strategies.Each chapter begins by defining all relevant key terms and concepts and provides pertinent background information so that the text will be accessible to newcomers to the field as well as to the expert. This text book should provide an excellent reference resource for investigators in tumor immunology, life sciences students, drug developers designing novel anti-cancer immunotherapeutics, and to other individuals with some scientific training wishing to gain a better understanding of the field of tumor immunotherapy.Although the field is evolving rapidly, we have taken pains to ensure that information was as up to date as possible as the text went to press.
  • 2014 Springer
    Cedrik Michael Britten, Sebastian Kreiter, Mustafa Diken, Hans-Georg Rammensee, editors.
    This book provides a comprehensive update on the state of the art in cancer immunology, which has rapidly evolved from a field of clinical research into an established discipline of oncology. The key recent developments in immuno-oncology are all covered, from the ever-changing immunological and regulatory frameworks to the most promising therapeutic concepts. Themes include combination therapies and personalized medicine, as well as identification of biomarkers to guide the clinical development of new approaches and to pinpoint the optimal treatment for each patient. The book acknowledges the continuing dynamic nature of the field as reflected in the development of next-generation immunotherapies that are already in clinical testing. Cancer Immunotherapy Meets Oncology is dedicated to the lifetime achievements of Christoph Huber, founder and chair of the Association for Cancer Immunotherapy (CIMT). It is also a tribute to those researchers and clinicians who are striving to develop novel diagnostics and tailored immunotherapies for the benefit of cancer patients.
  • 2007 Springer
    W. Archie Bleyer, Ronald D. Barr (eds.) ; [Karen H. Albritton, Marianne Phillips, Stuart E. Siegel, co-editors].
    Introduction / W. Archie Bleyer ... [et al.] -- History of adolescent oncology / Cameron K. Tebbi -- Epidemiology and etiology of cancer in adolescents and young adults / Jillian M. Birch and W. Archie Bleyer -- Access to care before and during therapy / Karen H. Albritton and Tim Eden -- Older adolescents and young adults with cancer, and clinical trials: lack of participation and progress in North America / W. Archie Bleyer, Troy Budd, and Michael Montello -- Acute lymphoblastic leukemia / James Nachman, Giuseppe Masera, and W. Archie Bleyer -- Acute myelogenous leukemia / Ursula Creutzig and William G. Woods -- Hodgkin lymphoma / Tanya M. Trippett ... [et al.] -- Non-hodgkin lymphoma / Catherine Patte, W. Archie Bleyer, and Mitchell S. Cairo -- Central nervous system tumors in adolescents and young adults / David A. Walker ... [et al.] -- Soft-tissue sarcomas / Karen H. Albritton, Andrea Ferrari, and Michela Casanova -- Bone sarcomas / Michael S. Isakoff ... [et al.] -- Malignancies of the ovary / Jubilee Brown, Thomas Olson, and Susan Sencer -- Testicuar tumors / John W. Cullen and Robert Fallon -- Non-germ-cell genitourinary tract tumors / Michael Leahy and W. Archie Bleyer -- Thyroid cancer / Steven G. Waguespack and Samuel A. Wells -- Malignant melanoma / Cynthia E. Herzog, W. Archie Bleyer, and Alberto S. Pappo -- Breast cancer / Marianne Phillips, Banu Arun, and W. Archie Bleyer -- Liver tumors / Marcio H. Malogolowkin, Arthur Zimmermann, and Jack Plaschkes -- Colorectal cancer / Wayne L. Furman, D. Ashley Hill, and Michael LaQuaglia -- Models of care and specialized units / Ian Lewis and Sue Morgan -- Drug compliance by adolescent and young adult cancer patients: challenges for the physician / Benjamin Gesundheit ... [et al.] -- Psychological support for adolescents and young adults / Christine Eiser and Aura Kuperberg -- Psychosocial support / Brad J. Zebrack, Mark A. Chesler, and Anthony Penn -- Health-related quality of life / Ernest R. Katz ... [et al.] -- Rehabilitation and exercise / Marilyn J. Wright -- Adolescent and young adult cancer survivors: late effects of treatment / Smita Bhatia ... [et al.] -- Ethical issues for the adolescent and young adult cancer patient: assent and end-of-life care / Susan Shurin and Eric Kodish -- Access to care after therapy / Karen E. Kinahan ... [et al.] -- Future health of survivors of adolescent and young adult cancer / Melissa M. Hudson and Kevin C. Oeffinger -- Information and resources for young adults and adolescents with cancer / David R. Freyer and Leonard J. Mattano -- Making ends meet: financial issues from the perspectives of patients and their healthcare team / David R. Freyer and Ronald D. Barr -- Challenges and opportunities - the way ahead / W. Archie Bleyer ... [et al.].
  • 2007 Springer
    edited by Igor Jurisica, Dennis A. Wigle, Bill Wong.
    Also available: Print – 2007
  • 2011 Springer
    edited by Boris R. Minev.
    This book represents a comprehensive description and evaluation of the most up-to-date approaches to cancer management. Each chapter, prepared by leading basic researchers and clinicians, provides an in depth description of a specific method for cancer management. The chemotherapy section of the book is updated to include the newest drugs as well as those currently in development. Organized by drug class, this section provides the latest information on most drugs, including their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance.
  • Unified set of cancer treatment guidelines involving the National Quality Forum, American Society for Clinical Oncology (ASCO) and the National Comprehensive Cancer Network (NCCN). These guidelines apply to breast and colorectal cancers.
  • 2010 STAT!Ref, Limited to 7 simultaneous users
    editors, Waun Ki Hong ... [et al.].
    Also available: Print – 2010
  • 2006
    Donald W. Kufe, Robert C. Bast Jr., William N. Hait ... [et al.], editors.
    Status: Not Checked OutLane Catalog Record
    Cancer biology -- Cancer immunology -- Cancer etiology -- Cancer epidemiology, prevention, and screening -- Clinical trials and outcomes assessment -- Cancer pathology -- Imaging -- Surgical oncology -- Radiation oncology -- Medical oncology -- Chemotherapy -- Chemotherapeutic agents -- Biotherapeutics -- Endocrine therapy -- Gene therapy -- Bone marrow transplantation -- Psycho-oncology -- Oncology nursing -- Cancer rehabilitation medicine -- Multidisciplinary management -- Pain and palliation -- Societal oncology -- Central nervous system -- The Eye -- Endocrine glands -- Head and neck -- The Thorax -- Gastrointestinal tract -- Genitourinary tract -- Female reproductive organs -- The Breast -- The Skin -- Bone and soft tissue -- Hematopoietic system -- Neoplasms in AIDS --- Unknown primary site -- Pediatric oncology -- Complications of cancer and their treatment -- Infection in the cancer patient -- Oncologic emergencies -- Oncology and informatics.
  • v. 1-, 2000- Springer
  • 2007 Springer
    edited by Stanley P.L. Leong.
    Also available: Print – 2007
  • 2009 Springer
    Gianfranco Baronzio, Giammaria Fiorentini, Christopher R. Cogle, editors.
  • 2013 CRCnetBASE
    edited by Sang Hyun Cho, Sunil Krishnan.
    Basic principles of radiation therapy of cancers / Laurence Court and Radhe Mohan -- Biological principles of radiosensitization / Vikas Bhardwaj ... [et al.] -- Principles and applications of hyperthermia combined with radiation / Mark Hurwitz -- Synthesis and surface modification of nanomaterials for tumor targeting / Glenn Goodrich -- Safety concerns for nanomaterials in nanomedicinal applications / Qingxin Mu ... [et al.] -- Imaging with nanoparticles / Amit Joshi -- Optical microscopy of plasmonic nanoparticles / Varun P. Pattani and James Tunnell -- X-ray fluorescence computed tomography imaging of nanoparticles / Bernard L. Jones and Sang Hyun Cho -- Gold nanoparticle-mediated radiosensitization / Devika B. Chithrani -- Quantification of gold nanoparticle-mediated radiation dose enhancement / Sang Hyun Cho and Bernard L. Jones -- Semiconductor nanomaterials for radiotherapy / Ke Sheng -- Radioactive gold nanoparticle for tumor therapy / Raghuraman Kannan, Kattesh V. Katti, and Cathy Cutler -- Nanoparticles for the selective radioprotection of normal tissues / Jacob M. Berlin and Kathy A. Mason -- Gold nanoparticle-mediated hyperthermia in cancer therapy / Dev K. Chatterjee and Sunil Krishnan -- Magnetic resonance thermometry imaging for gold nanoparticle-mediated thermal therapy / R. Jason Stafford and John D. Hazle -- Modeling of plasmonic heat generation from gold nanoparticles / Francisco Reynoso and Sang Hyun Cho -- Carbon nanotubes for thermal therapy / Ravi N. Singh ... [et al.] -- Regulatory issues for clinical translations / J. Donald Payne -- Clinical translations of nanotechnology : present and future outlook / Dev K. Chatterjee, Sang Hyun Cho, and Sunil Krishnan.
  • 2008 Springer
    edited by David Schiff, Santosh Kesari, Patrick Y. Wen.
    Overview -- Diagnostic studies -- Neurologic symptoms -- Direct complications of cancer -- Indirect complications of cancer -- Complications of cancer therapy -- Neurologic complications of specific malignancies.
  • 2011 ClinicalKey
    [edited by] Darrell S. Rigel [and others].
    Cancer of the Skin, edited by Drs. Rigel, Robinson, Ross, Friedman, Cockerell, Lim, Stockfleth, and Kirkwood, is your complete, multimedia guide to early diagnosis and effective medical and surgical treatment of melanoma and other skin cancers. Thoroughly updated with 11 new chapters, this broad-based, comprehensive reference provides you with the latest information on clinical genetics and genomics of skin cancer, targeted therapy for melanoma, the Vitamin D debate concerning the risks and benefits of sun exposure, and other timely topics. A new, multi-disciplinary team of contributors and editors comprised of leading experts in this field offers truly diverse perspectives and worldwide best practices.
  • 2010 Springer
    edited by M. Pilar Laguna, Peter Albers, Carsten Bokemeyer, and Jerome P. Richie.
    The book covers the complete field of testis cancer including the germ cell tumors and the stromal tumors, from epidemiology to new chemotherapeutic agents and schedules, throughout genetic features, risk factors, risk adapted treatments, role of different types of surgery and special clinical situations. Special attention is focused on fertility issues, late effects of the primary therapy and the economical aspects of the different treatment policies. As a result of the third Consensus Conference, a consensual follow-up can be devised and a chapter dedicated to this controversial and not yet defined matter.
  • 2016 Springer
    Alwin Krämer, Harald Löffler, editors.
    This book presents an up-to-date and thorough overview of cancer of unknown primary, encompassing topics ranging from epidemiology, tumor biology, and prognostic factors through to the most recent diagnostic and therapeutic advances. All aspects of management are covered, including radiological, nuclear medicine, and pathological diagnosis, site-specific therapies, platinum-based combination chemotherapy, radiotherapy, and novel targeted treatments. Clear guidance is offered on diagnosis of the tissue of origin by means of gene expression and micro-RNA analyses and its therapeutic implications. Detailed directions are also provided on the identification of subsets of patients with a more favorable prognosis, in whom specific treatment offers the chance of long-term survival or even cure. Readers will find Cancer of Unknown Primary to be an ideal source of practically oriented information that will assist in delivery of the best possible care for patients with this challenging diagnosis. .
  • 2013 Springer
    Magdi Hanna, Ben Zylicz, editors.
    Cancer remains a major challenge for medicine and it continues to claim lives and cause great suffering. Pain is a symptom experienced by most cancer patients regardless of disease stage, and less than 50% of cancer pain patients achieve effective pain and symptom control though available therapies. If these therapies are utilized correctly, many more patients can achieve effective control. While opioids are still seen as the mainstay of cancer pain treatment, it is necessary to examine whether this treatment strategy still holds true in the 21st century. Cancer Pain provides a comprehensive, up-to-date, practical guide to the management of pain in cancer patients. The book provides a clear, concise explanation of cancer pain syndromes, a modern understanding of the pathophysiological mechanism and an overview of recent developments in creating pre-clinical cancer pain models. It offers the reader the wide and improved options for management of cancer pain in clinical practice, including the use of opioid and non-opioid drugs, and defines the role of non-pharmacological methods for pain control. Cancer Pain also provides an overview of the latest developments in the management of cancer, which have major implications for the current and future thinking in cancer pain treatment strategy. This text is an invaluable resource for doctors, trainees and clinical nurse specialists in palliative medicine and oncology, and would be of interest to anyone who wishes to gain a better understanding of the complex nature of cancer pain and the tools available to alleviate it.
  • 2007
    [edited by] Michael J. Fisch, Allen W. Burton.
    Status: Not Checked OutLane Catalog Record
  • 2007 Springer
    H.-J. Senn, U. Kapp (eds.).
    Also available: Print – 2007
  • 2006 CRCnetBASE
    edited by Anne McTiernan.
  • 2014 Springer Protocols
    edited by Ann M. Bode and Zigang Dong.
    Combining computational and experimental methods for identifying molecular targets of phytochemicals / Ann M. Bode and Zigang Dong -- Common methods used for the discovery of natural anticancer compounds / Min Tang ... [et al.] -- Nrf2-target approaches in cancer chemoprevention mediated by dietary phytochemicals / Francisco Fuentes ... [et al.] -- Methods to analyze chemopreventive effect of silibinin on prostate cancer biomarkers protein expression / Gagan Deep, Swetha Inturi, and Rajesh Agarwal -- Approach to the evaluation of berries for cancer prevention with emphasis on esophageal cancer / Gary D. Stoner ... [et al.] -- Use of mouse models for lung cancer chemoprevention studies / Yian Wang ... [et al.] -- Azoxymethane plus dextran sulfate sodium-induced mouse colon cancer model for the study of dietary chemoprevention of inflammation-associated carcinogenesis / Ha-Na Lee, Hye-Won Yum, and Young-Joon Surh -- Use of seahorse extracellular flux analyzer in mechanistic studies of naturally occurring cancer chemopreventive agents / Michelle B. Moura ... [et al.] -- Utilizing RNA-seq to define phytochemical-induced alterations in insulin and IGF-regulated transcriptomes / Heather Beckwith and Douglas Yee -- Ex vivo use of keratinocytes from adult mice to define stem cell activities in cancer research / Rebecca J. Morris ... [et al.] -- Quantitation of acetaldehyde-DNA adducts : biomarkers of alcohol consumption / Silvia Balbo and Stephen S. Hecht -- Imaging tools in discovery and development of phytochemical chemopreventive agents / Marna Ericson -- Designing the chemoprevention trials of tomorrow : applying lessons learned from past definitive trials / Karen Colbert Maresso and Ernest Hawk.
  • 2009 Springer
    volume editors, Hansjörg Senn, Ursula Kapp, Florian Otto.
    Also available: Print – 2009
  • 2015 Ovid
    editors, Vincent T. DeVita, Jr, Theodore S. Lawrence, Steven A. Rosenberg.
  • 2012 Ovid
    editor, Ramaswamy Govindan ; assistant editors, Maria Q. Baggstrom, Thomas H. Fong, Janakiraman Subramanian.
  • 2008 (8th ed.) Ovid
    editors, Vincent T. DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg ; associate scientific advisors, Robert A. Weinberg, Ronald A. DePinho.
    Also available: Print – v. 1-2., 2008
  • 2011 Ovid
    [edited by] Vincent T. DeVita, Jr., Theodore S. Lawrence, Steven A. Rosenberg ; associate scientific advisors, Robert A. Weinberg, Ronald A. DePinho ; with 431 contributing authors.
    The Cancer Genome -- Mechanisms of Genomic Instability -- Epigenetics of Cancer -- Telomeres, Telomerase, and Cancer -- Cell Signaling Growth Factors and Their Receptors -- Cell Cycle -- Mechanisms of Cell Death -- Cancer Metabolism -- Angiogenesis -- Invasion and Metastasis -- Cancer Stem Cells -- Biology of Personalized Cancer Medicine -- Tobacco -- Cancer Susceptibility Syndromes -- DNA Viruses -- RNA Viruses -- Inflammation -- Chemical Factors -- Physical Factors -- Dietary Factors -- Obesity and Physical Activity -- Epidemiologic Methods -- Global Cancer Incidence and Mortality -- Trends in Cancer Mortality -- Surgical Oncology: General Issues -- Surgical Oncology: Laparoscopic Surgery -- Radiation Oncology -- Medical Oncology -- Assessment of Clinical Response -- Cancer Immunotherapy -- Health Services Research and Economics of Cancer Care -- Pharmacokinetics and Pharmacodynamics -- Pharmacogenomics -- Alkylating Agents -- Platinum Analogs -- Antimetabolites -- Topoisomerase-Interacting Agents -- Antimicrotubule Agents -- Targeted Therapy with Small Molecule Kinase Inhibitors -- Histone Deacetylase Inhibitors and Demethylating Agents -- Proteasome Inhibitors -- Poly(ADP-Ribose) Polymerase Inhibitors -- Miscellaneous Chemotherapeutic Agents -- Interferons -- Interleukin Therapy -- Antisense Agents -- Antiangiogenesis Agents -- Monoclonal Antibodies -- Endocrine Manipulation -- Preventive Cancer Vaccines -- Tobacco Dependence and Its Treatment -- Role of Surgery in Cancer Prevention -- Principles of Cancer Risk Reduction Intervention -- Retinoids, Carotenoids, and Other Micronutrients in Cancer Prevention -- Drugs and Nutritional Extracts for Cancer Risk Reduction (Chemoprevention) -- Principles of Cancer Screening -- Early Detection Using Proteomics -- Screening for Gastrointestinal Cancers -- Screening for Gynecologic Cancers -- Screening for Breast Cancer -- Screening for Prostate Cancer -- Screening for Lung Cancer -- Genetic Counseling -- Vascular Access and Specialized Techniques -- Interventional Radiology -- Functional Imaging -- Molecular Imaging -- Photodynamic Therapy -- Biomarkers -- Design and Analysis of Clinical Trials -- Molecular Biology of Head and Cancers -- Treatment of Head and Neck Cancer -- Rehabilitation after Treatment of Head and Neck Cancer -- Molecular Biology of Lung Cancer -- Non-Small Cell Lung Cancer -- Small Cell and Neuroendocrine Tumors of the Lung -- Neoplasms of the Mediastinum -- Molecular Biology of the Esophagus and Stomach -- Cancer of the Esophagus -- Cancer of the Stomach -- Molecular Biology of Pancreas Cancer -- Cancer of the Pancreas -- Molecular Biology of Liver Cancer -- Cancer of the Liver -- Cancer of the Biliary Tree -- Cancer of the Small Intestine -- Gastrointestinal Stromal Tumor -- Molecular Biology of Colorectal Cancer -- Cancer of the Colon -- Cancer of the Rectum -- Cancer of the Anal Region -- Molecular Biology of Kidney Cancer -- Cancer of the Kidney -- Molecular Biology of Bladder Cancer -- Cancer of the Bladder, Ureter, and Renal Pelvis -- Molecular Biology of Prostate Cancer -- Cancer of the Prostate -- Cancer of the Urethra and Penis -- Cancer of the Testis -- Molecular Biology of Gynecologic -- Cancer of the Cervix, Vagina, and Vulva -- Cancers of the Uterine Body -- Gestational Trophoblastic Neoplasms -- Ovarian Cancer, Fallopian Tube Carcinoma, and Peritoneal Carcinoma -- Molecular Biology of Breast Cancer -- Malignant Tumors of the Breast -- Molecular Biology of Endocrine Tumors -- Thyroid Tumors -- Parathyroid Tumors -- Adrenal Tumors -- Pancreatic Neuroendocrine Tumors -- Neuroendocrine (Carcinoid) Tumors and the Carcinoid Syndrome -- Multiple Endocrine Neoplasias -- Molecular Biology of Soft Tissue Sarcoma -- Soft Tissue Sarcoma -- Sarcomas of Bone -- Cancer of the Skin -- Molecular Biology of Cutaneous Melanoma -- Cutaneous Melanoma -- Molecular Biology of Central Nervous System Tumors -- Neoplasms of the Central Nervous System -- Molecular Biology of Childhood Cancers -- Solid Tumors of Childhood -- Leukemias and Lymphomas of Childhood -- Molecular Biology of Lymphomas -- Hodgkin Lymphoma -- Non-Hodgkin Lymphomas -- Cutaneous Lymphomas -- Primary Central Nervous System Lymphoma -- Molecular Biology of Acute Leukemias -- Management of Acute Leukemias -- Molecular Biology of Chronic Leukemias -- Chronic Myelogenous Leukemia -- Chronic Lymphocytic Leukemias -- Myelodysplastic Syndromes -- Plasma Cell Neoplasms -- Cancer of Unknown Primary Site -- Benign and Malignant Mesothelioma -- Peritoneal Surface Malignancy -- Intraocular Melanoma -- AIDS-Related Malignancies -- Transplantation-Related Malignancies -- Superior Vena Cava Syndrome -- Increased Intracranial Pressure -- Spinal Cord Compression -- Metabolic Emergencies -- Metastatic Cancer to the Brain -- Metastatic Cancer to the Lung -- Metastatic Cancer to the Liver -- Metastatic Cancer to the Bone -- Malignant Effusions of the Pleura and the Pericardium -- Malignant Ascites -- Paraneoplastic Syndromes -- Autologous Stem Cell Transplantation -- Allogeneic Stem Cell Transplantation -- Infections in the Cancer Patient -- Leukopenia and Thrombocytopenia -- Cancer-Associated Thrombosis -- Nausea and Vomiting -- Diarrhea and Constipation -- Oral Complications -- Pulmonary Toxicity -- Cardiac Toxicity -- Hair Loss -- Gonadal Dysfunction -- Fatigue -- Second Primary Cancers -- Neurocognitive Effects -- Cancer Survivorship -- Management of Cancer Pain -- Nutritional Support -- Sexual Problems -- Psychological Issues in Cancer -- Communicating News to the Cancer Patient -- Specialized Care of the Terminally Ill -- Community Resources -- Rehabilitation of the Cancer Patient -- Regulatory Issues -- Health Disparities in Cancer -- Cancer Information on the Internet -- Complementary, Alternative, and Integrative Therapies in Cancer Care.
  • 2008 Springer
    edited by Sayed S. Daoud.
    Proteomics technologies -- Cell signaling proteomics -- Tumor proteomics -- Bioinformatics and regulatory aspects of proteomics.
  • 2016 Springer
    Daniela Cristina Stefan, editor.
    1.Introduction: the need to conduct cancer research in developing countries -- 2.Steps of a research study: from research question to publication -- 3.Types of research designs -- 4.Clinical research in developing countries: An overview -- 5.The research protocol -- 6.Ethics of conducting cancer research in developing countries -- 7.Data management and statistics -- 8.Funding For Cancer Research and Clinical Studies in Low and Middle-Income Countries -- 9.International Collaboration in Cancer Research -- 10.Publication and dissemination of research findings.
  • 2014 Wiley
    editor, Vinagolu K. Rajasekhar.
    Oxytocin and vasopressin systems: oxytocin, vasopressin, and their interplay with gonadal steroids: essentials of cancer stem cells and conceptual modeling -- Theoretical and experimental foundations of the "cancer stem cell" model -- The hallmarks of prostate cancer stem cells -- Self-renewal, induced proliferation, and autonomous cell growth represent distinct modes of cell multiplication: relevance to the cancer stem cell theory -- Human embryonic stem cells and cancer: modeling disease in a dish -- Cancer stem cell as a result of a reprogramming-like mechanism: implications in tumor development and treatment -- A cancer stem cell model: an insight into the conversion of induced pluripotent stem cells to cancer stem-like cells -- Altruistic stem cells and cancer stem cells -- The emerging concept of EMT-induced cancer stem cells -- Models to study chronic myeloid leukemia cancer stem cells -- Cancer stem cells in melanoma: biomarkers and mathematical models -- Stem cells in liquid tumors -- Acute myeloid leukemia stem cells: updates and controversies -- Leukemia-initiating cells in acute lymphoblastic leukemia -- Stem cells in solid tumors -- Lung cancer stem cells and resistance to radiotherapy -- Prostate cancer cell heterogeneity and prostate cancer stem cells -- Glioblastoma stem cells drive tumor recurrence and patient relapse: what's the evidence? -- Stem cells and pancreatic cancer -- Melanoma subpopulations with cancer stem cell phenotypes -- Sarcoma stem cells -- Cancer stem cells in tumor metastasis perspective -- Cancer stem cells in metastasis and minimal residual disease -- Role of cancer stem cells in metastasis -- Cancer stem cells and the stromal microenvironment -- A perspective on breast cancer malignant progression: from cancer stem cell intra tumor heterogeneity to metastasis-initiating cells -- Novel and potential targets in cancer stem cells -- Targeting cancer stem cells: modulating embryonic stem cell signaling, epigenetics, and tumor metabolism -- Oct4, Oct1, and cancer stem cells -- The role of Cripto-1 in cancer and cancer stem cells -- Leptin signaling in the regulation of stem and cancer stem cells -- Tumor-initiating stem-like cells: carcinogenesis through toll-like receptors, environmental factors, and virus -- The role of epithelial cell polarity pathways on cancer stem cells -- Cancer-initiating cells, exosomes, and the premetastatic niche -- Microrna therapeutics to target brain tumor stem cells -- The riboproteome orchestrates self-renewal and cell fate in leukemia -- Clinical relevance of cancer stem cells in patients -- Targeting different states of breast cancer stem cells -- Difficulties in targeting the beating heart: therapeutic implications of the cancer stem cell hypothesis in melanoma -- Targeting cancer stem cells for overcoming drug resistance and cancer progression -- The role of cancer stem cells in tumor radioresistance.
  • 2011 Springer
    Alison L. Allan, editor.
    Cancer stem cells : historical perspectives and lessons from leukemia / Christopher R. Cogle -- Cancer stem cells in breast cancer / Jenny E. Chu and Alison L. Allan -- Cancer stem cells in brain cancer / Xin Wang, Chitra Venugopal, and Sheila K. Singh -- Cancer stem cells in colorectal cancer / Mauro Biffoni, Eros Fabrizi, and Lucia Ricci-Vitiani -- Cancer stem cells in pancreatic cancer / Jorge Dorado, Alicia G. Serrano, and Christopher Heeschen -- Cancer stem cells in prostate cancer / Paula Kroon ... [et al.] -- Cancer stem cells in melanoma / Ping Jin ... [et al.] -- Cancer stem cells in lung cancer / Jun Shen and Feng Jiang -- Cancer stem cells in ovarian cancer / Fang Fang ... [et al.] -- Cancer stem cells in hepatocellular cancer / Russell C. Langan and Itzhak Avital -- Cancer stem cells in head and neck cancer / Mark E.P. Prince and Samantha J. Davis -- Relationship between regulatory pathways in pluripotent stem cells and human tumors / Olga Gaidarenko and Yang Xu -- Influence of the embryonic microenvironment on tumor progression / Daniela Quail ... [et al.] -- The epithelial-to-mesenchymal transition and cancer stem cells / Jonas Fuxe -- Application of stem cell assays for the characterization of cancer stem cells / Pamela M. Willan and Gillian Farnie -- Zebrafish as a model to study stem cells in development, disease, and cancer / Viviana Anelli, Cristina Santoriello, and Marina C. Mione -- Imaging cancer stem cells / Paula Foster -- Mouse models for studying normal and cancer stem cells / David A. Hess -- Cancer stem cells and disease prognosis / Zeshaan A. Rasheed, Jeanne Kowalski, and William H. Matsui -- Mechanisms of radioresistance in cancer stem cells / Cleo Y-F Lee and Maximilian Diehn -- The role of ABC transporters in cancer stem cell drug resistance / Vera S. Donnenberg, Ludovic Zimmerlin, and Albert D. Donnenberg -- Resistance to endocrine therapy in breast cancer : are breast cancer stem cells implicated? / Ciara S. O'Brien ... [et al.] -- Future directions : cancer stem cells as therapeutic targets / Alysha K. Croker and Alison L. Allan -- Final thoughts : complexity and controversy surrounding the "cancer stem cell" paradigm / Craig Gedye, Richard P. Hill, and Laurie Ailles.
  • 2007 Springer
    O.D. Wiestler, B. Haendler, D. Mumberg, eds.
  • 2011 IARC
    edited by R. Sankaranarayanan, R. Swaminathan.
    Also available: Print – 2011
  • 2007 Springer
    Patricia A. Ganz, editor ; foreword by Sandra J. Horning.
    Cancer survivors: a physician's perspective / Patricia A. Ganz -- Cancer survivorship: a nursing perspective / Susan Leigh -- Oncology social work for survivorship / Patricia Fobair -- Survivorship research: past, present, and future / Julia H. Rowland -- Surveillance after primary therapy / Craig C. Earle -- Late effects of cancer treatments / Noreen M. Aziz -- Medical and psychosocial issues in childhood cancer survivors / Smita Bhatia ... [et al.] -- Medical and psychosocial issues in Hodgkin's disease survivors / Jon Håvard Loge and Stein Kaasa -- Medical and psychosocial issues in testicular cancer survivors / S.D. Fosså, L.B. Travis, and A.A. Dahl -- Medical and psychosocial issues in gynecologic cancer survivors / Karen Basen-Engquist and Diane C. Bodurka -- Medical, psychosocial, and health-related quality of life issues in breast cancer survivors / Julie Lemieux, Louise J. Bordeleau, and Pamela J. Goodwin -- Medical and psychosocial issues in prostate cancer survivors / Tracey L. Krupski and Mark S. Litwin -- Physical and psychosocial issues in lung cancer survivors / Linda Sarna, Frederic W. Grannis, and Anne Coscarelli -- Cancer survivorship issues in colorectal cancer / Clifford Y. Ko and Patricia A. Ganz -- Medical and psychosocial issues in transplant survivors / Karen L. Syrjala ... [et al.] -- Cancer survivorship issues in older adults / Karim S. Malek and Rebecca A. Silliman -- Second malignancies after radiation treatment and chemotherapy for primary cancers / Lydia B. Zablotska, Matthew J. Matasar, and Alfred I. Neugut -- Psychosocial rehabilitation in cancer care / Richard P. McQuellon and Suzanne C. Danhauer -- Reproductive complications and sexual dysfunction in cancer survivors / Leslie R. Schover -- The employment and insurance concerns of cancer survivors / Barbara Hoffman -- Cancer advocacy / Ellen L. Stovall -- The survivorship care plan: what, why, how, and for whom / Craig C. Earle ... [et al.]
  • 2008 Springer
    P. Rubin, L.S. Constine, L.B. Marks, P. Okunieff (eds.) ; with contributions by M.J. Adams ; foreword by L.W. Brady ... [et al.].
  • 2010 Springer Protocols
    edited by Michelle Webb.
  • 2014
    edited by Connie Henke Yarbro, Debra Wujcik, Barbara Holmes Gobel.
    Status: Not Checked OutLane Catalog Record
    Evidence-based symptom management -- Artharalgias and myalgias -- Cancer-related fatigue -- Menopausal symptoms -- Pain -- Sleep disturbances -- Hypersensitivity reactions to antineoplastic drugs -- Infection -- Constipation -- Diarrhea -- Nausea and vomiting -- Malignant ascites -- Bladder disturbances -- Bleeding and thrombotic complications -- Dyspnea -- Effusions -- The cancer cachexia syndrome -- Dysphagia -- Mucositis -- Xerostomia -- Increased intracranial pressure -- Peripheral neuropathy -- Alopecia -- Altered body image and sexual health -- Extravasation -- Lymphedema -- Ocular and otic complications -- Skin and nail bed changes -- Anxiety -- Cognitive dysfunction -- Depression -- Grief -- Spiritual distress -- Symptoms when death is imminent.
  • 2010 CRCnetBASE
    edited by Edwin Wang.
    A roadmap of cancer systems biology / Edwin Wang -- Network biology : the framework of systems biology / Jing-Dong Han -- Reconstructing gene networks using gene expression profiles / Mario Lauria and Diego di Bernardo -- Understanding cancer progression in protein interaction networks / Jinsheng Sun, Jie Li, and Edwin Wang -- From tumor genome sequencing to cancer signaling maps / Cong Fu and Edwin Wang -- Ubiquitin-mediated regulation of human signaling networks in normal and cancer cells / Cong Fu, Jie Li, and Edwin Wang -- MicroRNA regulation of networks of normal and cancer cells / Pradeep Kumar Shreenivasaiah, Do Han Kim, and Edwin Wang -- Network model of survival signaling in T-cell large granular lymphocyte leukemia / Ranran Zhang, Thomas P. Loughran Jr., and Réka Albert -- Cancer metabolic networks : metabolic pathways modelling and metabolomics in cancer research / Miroslava Cuperlovic-Culf -- Warburg revisited : modeling energy metabolism for cancer systems biology / Mathieu Cloutier -- Cancer gene prediction using a network approach / Xuebing Wu and Shao Li -- Cancer genomics to cancer biology / Maria Luz Jaramillo and Chabane Tibiche -- Epithelial-to-mesenchymal transition (EMT) : the good, the bad, and the ugly / Anne EG Lenferink -- Tumors and their microenvironments / Nicholas R. Bertos and Morag Park -- Tumor angiogenesis : cell-microenvironment interactions / Ally Pen, Danica B. Stanimirovic, and Maria J. Moreno -- Modeling tools for cancer systems biology / Wayne Materi and David S. Wishart -- Advanced visualization, analysis, and inference of biological networks using visANT / Zhenjun Hu -- Gene set and pathway-based analysis for cancer omics / Dougu Nam and Seon-Young Kim -- SH2 domain signaling network and cancer / Shawn S.-C. Li and Thamara K.J. Dayarathna -- Data sources and computational tools for cancer systems biology / Yun Ma, Pradeep Kumar Shreenivasaiah, and Edwin Wang.
  • 2011 Springer
    Alfredo Cesario, Frederick B. Marcus, editors.
    pt. 1. Introduction and background -- pt. 2. Laboratory, clinical, data and educational resources -- pt. 3. Bioinformatics and systems biology analysis -- pt. 4. Diagnosis, clinical and treatment applications -- pt. 5. Perspectives and conclusions.
  • 2013 Springer
    You Han Bae, Randall J. Mrsny, Kinam Park, editors.
    A Time Travel Journey Through Cancer Therapies -- Nanotechnology for Cancer Treatment: Possibilities & Limitations -- Vascular Targeting Approaches to Treat Cancer -- Tumor Immunotherapy by Utilizing a Double-Edged Sword Chemokines -- Cancer Biology: Some Causes for a Variety of Different Diseases -- Cancer Stromal Targeting (CAST) Therapy and Tailored Antibody Drug Conjugate Therapy Depending on Nature of Tumor Stroma -- Cancer Cell Respiration: Hypoxia and pH in Solid Tumors -- Tumor Vasculature, EPR Effect, and Anticancer Nanomedicine: Connecting the Dots -- Pressure Gradients in Solid Tumors -- The ADAMs: New Therapeutic Targets for Cancer? -- Role of the Extracellular Matrix Enzyme Activities and Metastasis -- The Role of Non-Cancerous Cells in Cancer: Pancreatic Ductal Adenocarcinoma as Model to Understand the Impact of Tumor Microenvironment on Epithelial Carcinogenesis -- Heterogeneity of Cancers and its Implication for Targeted Drug Delivery -- A Study of Cancer Heterogeneity: From Genetic Instability to Epigenetic Diversity in Colorectal Cancer -- Nanotherapeutics in Multidrug Resistance -- Stem Cells and Cancer -- Mechanisms of Metastasis -- Cancer-Specific Ligand/Receptor Interactions -- Targeting Drugs to Cancer: A Tough Journey to the Tumor Cell -- Long Circulation and Tumor Accumulation -- Convective and Diffusive Transport in Drug Delivery -- Intravital Real-Time Confocal Laser Scanning Microscopy for the in Situ Evaluation of Nanocarriers -- The EPR effect in Cancer Therapy -- In Vitro 3-dimensional Cancer Culture Model -- Complex Transport Around Tumor: Need for Realistic In Vitro Tumor Transport Model -- The Missing Components Today and the New Treatments Tomorrow.
  • 2012
    edited by Richard E. LaFond.
    Status: Not Checked OutLane Catalog Record
    We live in an era in which scientific information grows by the day and is so specialized that no one person can possibly absorb and kept abreast of the literature. Substantial developments in science and medicine, powered by developing technologies such as genetic sequencing, proteomics, and nanobiology, have driven cancer research forward, and a review of where we are now is desperately needed. A collection of twenty-five focused chapters written by leading researchers at the forefront of cancer research. Authors present the current state of knowledge in chapters on the role of heredity, cancer and telomeres, tumor resistance, and microRNAs in the pathogenesis of cancer, and map out areas of future research and advancement.
  • 2015 ScienceDirect
    edited by Xiaoyuan Chen, Stephen Wong.
    I: In vitro diagnostics. Cancer theranostics: an introduction -- Genomics-based cancer theranostics -- Proteomics-based theranostics -- II: Molecular imaging. Radionuclide imaging of cancer therapy -- Near-infrared fluorescence imaging probes for cancer diagnosis and treatment -- Bioluminescence imaging of cancer therapy -- Magnetic resonance imaging of cancer therapy -- Ultrasound imaging of cancer therapy -- Photoacoustic imaging for cancer diagnosis and therapy guidance -- III: Imaging-guided therapy. Multimodality image-guided lung intervention systems -- Label-free molecular vibrational imaging for cancer diagnosis -- Multimodality image-guided treatment -- Medical robotics for cellular and molecular imaging -- IV: Theranostic platforms. Porphyrins for imaging, photodynamic therapy, and photothermal therapy -- Magnetic resonance imaging and alternating magnetic fields -- Ultrasound for drug/gene delivery -- Radionuclides for imaging and therapy in oncology -- Noble metal nanoparticle platform -- Cancer theranostics with carbon-based nanoplatforms -- Silica nanoparticle platform -- Quantum dots for traceable therapeutic delivery -- Polymer- and protein-based nanotechnologies for cancer theranostics -- V: Other. Clinical translation and regulations of theranostics -- Scale-up production of theranostic nanoparticles -- Market considerations for nanomedicines and theranostic nanomedicines -- Application of theranostics to measure and treat cell heterogeneity in cancer.
  • v. 122-, 2004- Springer
    Freireich, Emil J.; McGuire, William L.; Rosen, Steven T.
  • 2015 ScienceDirect
    edited by Richard A. Anderson, Norah Spears.
    Section I. Clinical -- Section II. Laboratory models -- Section III. Strategies to protect the ovary.
  • 2014 Springer Protocols
    edited by Michael J.P. Lawman and Patricia D. Lawman.
    Single Step Antigen Loading and Maturation of Dendritic Cells Through mRNA Electroporation of a Tumor-Associated Antigen and a TriMix of Costimulatory Molecules -- Generation of Multiple Peptide Cocktail-Pulsed Dendritic Cells as a Cancer Vaccine -- Pulsing Dendritic Cells with Whole Tumor Cell Lysates -- Antigen Trapping by Dendritic Cells for Anti-Tumor Therapy -- Ex Vivo Loading of Autologous Dendritic Cells with Tumor Antigens -- Tumor Antigen/Cytokine-Pulsed Dendritic Cells in Therapy Against Lymphoma -- Dendritic Cells Primed with Protein-Protein Fusion Adjuvant -- Antigen-Specific mRNA Transfection of Autologous Dendritic Cells -- Electroporation of Dendritic Cells with Autologous Total RNA from Tumor Material -- Dendritic Cells Transfected with Adenoviral Vectors as Vaccines -- Genetic Modification of Dendritic Cells with RNAi -- Fast Monocyte-Derived Dendritic Cells-Based Immunotherapy -- Intratumoral Injection of BCG-CWS Pretreated Dendritic Cells Following Tumor Cryoablation -- Exploiting the CD1d-iNKT Cell Axis for Potentiation of DC-Based Cancer Vaccines -- Modification of T Lymphocytes to Express Tumor Antigens -- Genetic Modification of Mouse Effector and Helper T Lymphocytes Expressing a Chimeric Antigen Receptor -- Genetic Modification of Cytotoxic T Lymphocytes to Express Cytokine Receptors -- Monitoring the Frequency and Function of Regulatory T Cells and Summary of the Approaches Currently Used to Inhibit Regulatory T Cells in Cancer Patients -- Cytokine Activation of Natural Killer Cells -- Loading of Acute Myeloid Leukemia Cells with Poly(I:C) by Electroporation -- Autologous Tumor Cells Engineered to Express Bacterial Antigens -- Tumor Cell Transformation Using Antisense Oligonucleotide -- The Direct Display of Costimulatory Proteins on Tumor Cells as a Means of Vaccination for Cancer Immunotherapy -- Cloning Variable Region Genes of Clonal Lymphoma Immunoglobulin for Generating Patient-Specific Idiotype DNA Vaccine -- Heat Shock Proteins Purified from Autologous Tumors Using Antibody-Based Affinity Chromatography -- Invariant Chain-Peptide Fusion Vaccine Using HER-2/neu -- TLR-9 Agonist Immunostimulatory Sequence Adjuvants Linked to Cancer Antigens -- Production of Multiple CTL Epitopes from Multiple Tumor-Associated Antigens -- Preparation of Polypeptides Comprising Multiple TAA Peptides -- Idiotype Vaccine Production Using Hybridoma Technology -- Preparation of Cancer-Related Peptide Cocktails that Target Heterogeneously-Expressed Antigens -- Making an Avipoxvirus Encoding a Tumor-Associated Antigen and a Costimulatory Molecule -- Bacterial Vectors for the Delivery of Tumor Antigens -- Preparation of Peptide Microspheres Using Tumor Antigen-Derived Peptides -- Production of Antigen-Loaded Biodegradable Nanoparticles and Uptake by Dendritic Cells -- Development of Plasmid-Lipid Complexes for Direct Intratumoral Injection -- The Use of Dendritic Cells for Peptide-Based Vaccination in Cancer Immunotherapy -- Advances in Host and Vector Development for the Production of Plasmid DNA Vaccines -- Challenges Facing the Development of Cancer Vaccines -- Future of Cancer Vaccines.
  • 2015
    Juan Alvarado Valdivia.
    Status: Not Checked OutLane Catalog Record
    Recounts the author's experience as a cancer patient. He was diagnosed with stage 2A Hodgkin lymphoma at age 30, and was cancer free in 2010, and five years later considered in complete remission.
  • 2015 Springer
    Joachim Weis, Markus Horneber.
    Cancer-related fatigue (CrF) is increasingly recognized as a significant problem for patients with cancer at all stages, including those undergoing therapy and in remission. In fact, studies have shown that CrF causes patients more distress than pain, nausea, or vomiting and yet fatigue is still often undertreated and rarely studied. However, several new treatments such as are being investigated to determine the most effective ways to manage this debilitating symptom and improve patient quality of life. Cancer-Related Fatigue will provide a concise overview of this condition, with an evidence-based discussion of diagnosis, treatment, and long-term management.
  • 2009 Springer
    Valérie Delavigne.
  • 2010 Springer
    coordonné par Jean-François Morère, Muriel Rainfray, Emmanuel Mitry.
  • 2009 Springer Protocols
    edited by Ronald L. Cihlar and Richard A. Calderone.
    Isolation of dendritic cells from human blood for in vitro interaction studies with fungal antigens / T. Sreevalsan -- Detection and quantitation of antifungal SIgA antibodies in body fluids / Michael F. Cole -- Phagocytosis and killing assays for Candida species / Chen Du and Richard A. Calderone -- Immunization protocols for use in animal models of candidiasis / Esther Segal and Hana Sandovsky-Losica -- Penetration of antifungal agents through Candida biofilms / L. Julia Douglas -- Candida biofilm analysis in the artificial throat using FISH / Bastiaan P. Krom ... [et al.] -- Conditions for optimal Candida biofilm development in microtiter plates / Bastiaan P. Krom ... [et al.] -- Animal models of candidiasis / Cornelius J. Clancy, Shaoji Cheng, and Minh H. Nguyen -- Candida albicans gene expression in an in vivo infection model / Michael D. Kruppa -- In vitro and ex vivo assays of virulence in Candida albicans / Richard A. Calderone -- Biotyping of Candida albicans and other fungi by yeast killer toxins sensitivity / Luciano Polonelli and Stephania Conti -- DNA fingerprinting Candida species / Claude Pujol and David R. Soll -- The application of tandem-affinity purification to Candida albicans / Chris Blackwell and Jeremy D. Brown -- Preparation of samples for proteomic analysis of the Candida albicans cell wall / Neeraj Chauhan -- Reporter gene assays in Candida albicans / Joy Sturtevant -- Genetic transformation of Candida albicans / Ana M. Ramon and William A. Fonzi -- Large-scale gene disruption using the UAU1 cassette / Clarissa J. Nobile and Aaaron P. Mitchell -- Standard growth media and common techniques for use with Candida albicans / Neeraj Chauhan and Michael D. Kruppa.
  • 2014 ScienceDirect
    Jane E. Sykes.
    Basic principles in the diagnosis and management of small animal infection -- Laboratory diagnosis of canine and feline infectious diseases -- Isolation in cell culture -- Immunoassays -- Isolation and identification of aerobic and anaerobic bacteria -- Isolation and identification of fungi -- Nucleic acid detection assays -- Antiinfective therapy -- Principles of antiinfective therapy -- Antiviral and immunomodulatory drugs -- Antibacterial drugs -- Antifungal drugs -- Antiprotozoal drugs -- Basic principles for infection control -- Infection control programs for dogs and cats -- Immunization -- Major infectious diseases and their etiologic agents -- Viral diseases -- Rabies -- Canine parvovirus infections and other viral enteritides -- Canine distemper virus infection -- Canine herpesvirus infection -- Canine viral respiratory infections -- Infectious canine hepatitis -- Feline panleukopenia virus infection and other viral enteritides -- Feline coronavirus infection -- Feline immunodeficiency virus infection -- Feline leukemia virus infection -- Feline respiratory viral infections -- Feline poxvirus infections -- Pseudorabies -- Viral papillomatosis -- Vector-borne and other viral encephalitides -- Bacterial diseases -- Ehrlichiosis -- Anaplasmosis -- Rocky mountain spotted fever -- Salmon poisoning disease -- Coxiellosis and q fever -- Chlamydial infections -- Streptococcal and enterococcal infections -- Staphylococcus infections -- Gram-negative bacterial infections -- Anaerobic bacterial infections -- Bordetellosis -- Cell wall-deficient bacterial infections -- Mycoplasma infections -- Hemoplasma infections -- Actinomycosis -- Nocardiosis -- Mycobacterial infections -- Salmonellosis -- Enteric Escherichia coli infections -- Campylobacteriosis -- Enteric clostridial infections -- Gastric Helicobacter-like infections -- Leptospirosis -- Lyme borreliosis -- Bartonellosis -- Canine brucellosis -- Tetanus and botulism -- Yersinia pestis (plague) and other yersinioses -- Tularemia -- Bite and scratch wound infections -- Fungal and algal diseases -- Dermatophytosis -- Malassezia infections -- Blastomycosis -- Histoplasmosis -- Cryptococcosis -- Coccidioidomycosis -- Sporotrichosis -- Aspergillosis -- Rhinosporidiosis -- Candidiasis -- Miscellaneous fungal diseases -- Pythiosis, lagenidiosis, and zygomycosis -- Protothecosis -- Pneumocystosis -- Protozoal diseases -- Toxoplasmosis -- Neosporosis -- Leishmaniosis -- Babesiosis -- Cytauxzoonosis -- Canine and feline hepatozoonosis -- Trypanosomiasis -- Giardiasis -- Trichomoniasis -- Cryptosporidiosis -- Isosporiasis -- Miscellaneous protozoal diseases -- Infections of selected organ systems -- Pyoderma, otitis externa, and otitis media -- Osteomyelitis, discospondylitis, and infectious arthritis -- Infections of the cardiovascular system -- Bacterial bronchopneumonia and pyothorax -- Intra-abdominal infections -- Bacterial infections of the genitourinary tract -- Bacterial meningitis -- Vaccination schedules for dogs and cats.
  • 2009 Springer
    Patricia H. Reggio, editor.
  • 2014 Wiley
    [edited by] Vincenzo Di Marzo.
    Looking ahead after 50 years of research on cannabinoids / Raphael Mechoulam -- Cannabinoid receptor intracellular signaling : the long journey from binding sites to biological effects / Lawrence C. Blume, Khalil M. Eldeeb, and Allyn C. Howlett -- Endocannabinoid biochemistry : what do we know after 50 years? / Filomena Fezza and Mauro Maccarrone -- Genetic dissection of the endocannabinoid system and how it changed our knowledge of cannabinoid pharmacology and mammalian physiology / Beat Lutz -- Cannabinoids, endocannabinoids, and stress / Cecilia J. Hillard, Qing-song Liu, XiaoQian Liu, Bin Pan, Christopher J. Roberts, and Leyu Shi -- Cannabinoids and the brain : new hopes for new therapies / Javier Fernández-Ruiz, Mariluz Hernández, and Yolanda García-Movellán -- Potential therapeutic applications of cannabinoids in gastrointestinal and liver diseases : focus on tetrahydrocannabinol pharmacology / Paolo Caraceni, Francesca Borrelli, Ferdinando A. Giannone, and Angelo A. Izzo -- Years of cannabinoid research and the need for a new nomenclature / Vincenzo Di Marzo and Luciano De Petrocellis.
  • 2008 Springer
    Attila Köfalvi, editor ; editorial and chapters 1, 9, 14, 22 were proofed by Zsófia Gombár.
  • 2005 Springer
    edited by R. Mechoulam.
  • 2010 CRCnetBASE
    editor, Piero Carninci.
    The ouput of eukaryotic genomes is much more complex than expected. Genes produce different variants of RNAs from multiple promoters. One of the ultimate targets of biological analysis is to establish a relationship between the messenger RNAs that are transcribed from the genome and the genomic regions that control their expression - the promoters - in order to decipher the networks that regulate gene expression and the transcription factors that act as master regulators of transcriptional control. Novel technologies have recently appeared that allow deciphering of transcriptional network, based on the identification of the starting site of gene transcription, with the simultaneous measurement of expression level and identification of the promoter elements. These tagging technologies (including cap-analysis gene expression - CAGE - and others) are further boosted from the development of the novel generation of sequencing instruments, which allow transcriptional profiling by sequencing at the cost of microarray experiments. This book is a guide for users of new technologies, as it includes accurately proven protocols, allowing readers to prepare their samples for experiments. Additionally, it provides a guide for the bioinformatics tools that are available for the analysis of the obtained tags, including the design of the software, the sources and web information where they can be downloaded. Finally, the book provides examples of the application of these technologies to identify promoters, annotate genomes, identify new RNAs and reconstruct models of transcriptional control. Although examples mainly regard mammalians, the discussion expands to other groups of eukaryotes, where these approaches are complementing genome sequencing.
  • 2013 CRCnetBASE
    Ephraim Philip Lansky, Helena Maaria Paavilainen, Shifra Lansky.
  • 2008 Springer Protocols
    edited by Philippe Schmitt-Kopplin.
    Part I: Analyte-oriented -- Determination of small icons with capillary electrophoresis and contactless conductivity detection / Andreas Zemann, Irene Rohregger, and Roland Zitturi -- Metal analysis with capillary zone electrophoresis / Ashok Kumar Malik - Measurement of low-molecular-weight carboxylic acids in ambient air and vehicle emission by capillary electrophoresis / Ewa Dabek-Zlotorzynska and Valbona Celo -- Determination of aliphatic low-molecular-weight and biogenic amines by capillary zone electrophoresis / Agnes Fekete ... [et al.] -- Capillary electrophoretic analysis of organic pollutants / Ashok Kumar Malik, Jatinder Singh Aulakh, and Varinder Kaur -- Capillary electrophoresis with laser-induced fluorescence: environmental applications / Lee Riddick and William C. Brumley -- Practical considerations for the analysis of ionic and neutral organic molecules with capillary electrophoresis/mass spectrometry / Moritz Frommberger, Matthias Englmann, and Philippe Schmitt-Kopplin -- Analysis of the enantiomers of chiral pesticides and other pollutants in environmental samples by capillary electrophoresis / Arthur W. Garrison, Philippe Schmitt-Kopplin, and Jimmy K. Avants -- Capillary electrophoresis of tropane alkaloids and glycoalkaloids occurring in solanaceae plants / Tommaso R. I. Cataldi and Giuliana Bianco -- Capillary electrophoresis for pharmaceutical analysis / Alex Marsh ... [et al.] -- Capillary electrophoresis of neutral carbohydrates: mono-, oligosaccharides, and glucosides / Cristiana Campa and Marco Rossi -- Capillary electrophoresis of sugar acids / Cristiana Campa, Edi Baiutti, and Anna Flamigni -- Use of capillary electrophoresis for polysaccharide studies and applications / Amelia Gamini ... [et al.] -- Analysis of oligonucleotides using capillary zone electrophoresis and electrospray mass spectrometry / An Willems, Dieter L. Deforce, and Jan Van Bocxlaer -- Separation of DNA by capillary electrophoresis / Bruce McCord, Brittany Hartzell-Baguley, and Stephanie King -- Capillary electrophoresis of oxidative DNA damage / Guowang Xu ... [et al.] -- Capillary electrophoresis of gene mutation / Guowang Xu ... [et al.] -- Biomedical applications of amino acid detection by capillary electrophoresis / Giuseppe E. De Benedetto -- Separation of peptides by capillary electrophoresis / Gerhard K. E. Scriba and Arndt Psurek -- Analysis of proteins by capillary electrophoresis / Christian W. Huck and Günther K. Bonn -- Separation of synthetic (Co)polymers by capillary electrophoresis techniques / Hervé Cottet and Pierre Gareil -- Capillary electrophoresis separation of microorganisms / Bartolomé M. Simonet, Angel Ríos, and Miguel Valcárcel -- Part II: Methods-oriented -- A semi-empirical approach for a rapid comprehensive evaluation of the electrophoretic behaviors of small molecules in free-zone electrophoresis / Philippe Schmitt-Kopplin and Agnes Fekete -- The CE way of thinking: all is relative! / Philippe Schmitt-Kopplin and Agnes Fekete -- Adsorbed cationic polymer coatings for enhanced capillary electrophoresis/mass spectrometry of proteins / Sara Ullsten, Aida Zuberovic, and Jonas Bergquist -- On-column ligand/receptor derivatization coupled to affinity capillary electrophoresis / Jose Zavaleta ... [et al.] -- On-line concentration of environmental pollutant samples by using capillary electrophoresis / Janpen Intaraprasert and Philip J. Marriott -- Free-flow electrophoresis system for proteomics applications / Gerhard Weber and Robert Wildgruber -- Microemulsion electrokinetic chromatography / Wolfgang W. Buchberger -- Micellar electrokinetic chromatography of aminoglycosides / Ulrike Holzgrabe, Stefanie Laug, and Frank Wienen -- Capillary electrochromatography and on-line concentration / Guichen Ping ... [et al.] -- Analysis of alkaloids in single plant cells by capillary electrophoresis / Katrin Wieland, Björn Thiele, and Uli Schurr -- Multi-dimensional capillary electrophoresis and chromatography for proteomic analysis / Mingxia Gao and Xiangmin Zhang.
  • 2008 ScienceDirect
    edited by Satinder Ahuja, M. llias Jimidar.
    Overview of Capillary Electrophoresis in Pharmaceutical Analysis -- Theoretical Consideration in Performance of Various Modes of CE -- Equipment Considerations for Capillary Electrophoresis -- Method Development for Pharmaceutical Analysis -- Role of CE in Drug Substance and Drug Product Development -- General Considerations to Improve Performance of CE Methods -- Overview of Current Regulatory Guidance -- Qualification of CE Instrumentation -- Robustness Testing of CE Methods -- Validation of Analytical Methods Using Capillary Electrophoresis-- The Need for CE Methods in Pharmacopeial Monographs -- CE in Impurity Profiling of Drugs -- Ion Analysis Using Capillary Electrophoresis -- Role of CE in Biopharmaceutical Development and Quality Control -- Capillary Electrophoresis and Bioanalysis -- CE as an Orthogonal Technique to Chromatography -- Capillary Electrochromatography of Pharmaceuticals -- Coupling CE and Chip-based Devices and Mass Spectrometry.
  • 2013 Springer Protocols
    edited by Nicola Volpi and Francesca Maccari.
    Recent advances in capillary electrophoresis-based proteomic techniques for biomarker discovery / Chenchen Wang, Xueping Fang, and Cheng S. Lee -- Capillary electrophoresis-mass spectrometry of carbohydrates / Joseph Zaia -- Approaches to enhancing the sensitivity of carbohydrate separations in capillary electrophoresis / M.C. Breadmore -- Determination of monosaccharides derivatized with 2-aminobenzoic acid by capillary electrophoresis / Mitsuru Abo, Li-ping He, Kae Sato and Akira Okubo -- Determination of mono-, di-, and oligosaccharides by capillary electrophoresis with capacitively coupled contactless conductivity detection / Claudimir Lucio do Lago, Thiago Nogueira, Lucas Blanes and Renata Mayumi Saito -- Separation of chitooligosaccharides in acidic solution by capillary electrophoresis / Toshiaki Hattori, Nobuhiro Anraku, and Ryo Kato -- Capillary electrophoresis for the analysis of glycosaminoglycan-derived disaccharides / Yuqing Chang, Bo Yang, Amanda Weyers and Robert J. Linhardt -- High-throughput capillary electrophoresis-mass spectrometry : from analysis of amino acids to analysis of protein complexes / Mehdi Moini -- Separation of amino acids by capillary electrophoresis with light-emitting diode-induced fluorescence in the presence of electroosmotic flow / Ming-Mu Hsieh and Po-Ling Chang -- Quantification of arginine and dimethylated arginines in human plasma by field-amplified sample injection capillary electrophoresis UV detection / Angelo Zinellu, Salvatore Sotgia, Luca Deianna and Ciriaco Carru -- Capillary electrophoresis-mass spectrometry for peptide analysis : target-based approaches and proteomics/peptidomics strategies / Carolina Simó, Alejandro Cifuentes, and Václav Kašička -- High resolution proteome/peptidome analysis of body fluids by capillary electrophoresis coupled with MS / Amaya Albalat, Vasiliki Bitsika, Petra Zurbig, Justyna Siwy and William Mullen -- Contribution of CE to the analysis of protein or peptide biomarkers / Kiarach Mesbah, Romain Verpillot, Franc̦ois de l'Escaille, Jean Bernard Falmagne and Myriam Taverna -- Highly charged polyelectrolyte coatings to prevent adsorption during protein and peptide analysis in capillary electrophoresis / Reine Nehmé and Catherine Perrin -- Capillary electrophoresis with laser-induced fluorescence detection of proteins from two types of complex sample matrices : food and biological fluids / Raul Garrido-Medina, Angel Puerta, Cristina Pelaez-Lorenzo, Zuly Rivera-Monroy, Andras Guttman, Jose Carlos Diez-Masa and Mercedes de Frutos -- Automated capillary electrophoresis in the screening for hemoglobinopathies / Frédéric Cotton, Fleur Wolff, and Béatrice Gulbis -- Protein fingerprinting of Staphylococcus aureus by capillary electrophoresis with on-capillary derivatization and laser-induced fluorescence detection / Cristina Pelaez-Lorenzo, Maria Teresa Veledo, Ramon Gonzales, Mercedes de Frutos and Jose Carlos Diez-Masa -- Capillary electrophoresis of seed storage proteins : the separation and identification of microheterogeneous rice glutelin subunits / Tomoyuki Katsube-Tanaka -- Evaluating amyloid beta (A[beta]) 1-40 degradation by capillary electrophoresis / Benjamin J. Alper and Walter K. Schmidt -- Capillary electrophoresis for protein profiling of the dimorphic, pathogenic fungus, penicillium marneffei / Julie M. Chandler, Heather R. Trenary, Gary R. Walker and Chester R. Cooper -- Capillary electrophoretic enzyme assays / Gerhard K.E. Scriba, Hans Abromeit, Martina Hense and Yi Fan -- A methodology for detection and quantification of esterase activity / Ana L. Simplício, Ana S. Coroadinha, John F. Gilmer and Joana Lamego -- Enzyme inhibitor screening by CE with and on-column immobilized enzyme microreactor created by an ionic binding technique / Chao Liu, Qianqian Zhang, and Jingwu Kang -- Fluorescent lipids as probes for sphingosine kinase activity by capillary electrophoresis / Philip M. Yangyuoru, Latanya Hammonds-Odie and Simon M. Mwongela -- Assessment of DNA damage by micellar electrokinetic chromatography / Paolo Fattorini, Giorgio Marrubini, Pierangela Grignani, Solange Sorc̦aburu-Cigliero and Carlo Previderé.
  • 2009 ClinicalKey
    Louis R. Caplan.
    1. Introduction and perspective -- 2. Basic pathology, anatomy, and pathophysiology of stroke -- 3. Diagnosis and the clinical encounter -- 4. Imaging and laboratory diagnosis -- 5. Treatment -- 6. Large artery occlusive disease of the anterior circulation -- 7. Large vessel occlusive disease of the posterior circulation -- 8. Penetrating and branch artery disease -- 9. Brain embolism -- 10. Hypoxic-ischemic encephalopathy, cardiac arrests, and cardiac encephalopathy -- 11. Nonatherosclerotic vasculopathies -- 12. Subarachnoid hemorrhage, aneurysms, and vascular malformations -- 13. Intracerebral hemorrhage -- 14. Stroke in children and young adults -- 15. Spinal cord vascular disease -- 16. Cerebral venous thrombosis -- 17. Stroke prevention -- 18 Complications in stroke patients -- 19. Recovery and rehabilitation.
    Also available: Print – 2009
  • 2014 Springer
    Omar M.E. Abdel-Salam, editor.
    This volume provides an up-to-date account of the achievements pertaining to the application of capsaicin and capsaicin-like molecules in the therapy of various human ailments such as pain, non-allergic rhinitis, obesity, tumors, and gastrointestinal, dermatologic, and urologic disorders. It discusses the basic functions of the capsaicin receptor (TRPV1), its mechanisms of action, and its role in physiological and pathological processes. The text focuses on the most recent progress in the use of capsaicin and capsaicin-like molecules as a therapeutic agent and highlights potential pharmaceutical implications of further TRPV1 research. The chapters are written by noted experts in their fields of endeavor. This book offers both clinicians and researchers valuable resource and reference material on the subject that will stimulate future research.
  • 2007
    Jay R. Goldberg.
  • 2012 Atypon
    Jay R. Goldberg.
    The biomedical engineering senior capstone design course is probably the most important course taken by undergraduate biomedical engineering students. It provides them with the opportunity to apply what they have learned in previous years, develop their communication, teamwork, project management,and design skills,and learn about the product development process. It prepares students for professional practice and serves as a preview of what it will be like to work as a biomedical engineer.
  • 2008 ClinicalKey
    edited by Douglas O. Faigel, David R. Cave.
    History and future / Paul Swain -- How does the capsule work? / Moti Frish -- How to set up the suite and perform capsule endoscopy / Doug Morgan -- Reading, reporting, and training / Doug Adler -- The role of surgery in capsule endscopy / Calvin W. Lee and David R. Cave -- Systematization of terminology for capsule endoscopy / Michel Delvaux and Gerard Gay -- Normal small bowel and normal variants of the small bowel / Klaus Mergener -- Approach to the patient with GI bleeding / Marco Pennazio -- Approach to the patient with inflammatory bowel disease / Tanja Kühbacher and Stepfan Schreiber -- Approach to the patient with abdominal pain / Martin Keuchel -- Approach to the patient with obstruction / Maria Elena Riccioni ... [et al.] -- Approach to the pediatric patient / Victor L. Fox -- Use of capsule endoscopy for the evaluation of inflammatory bowel disease / Stuart L. Triester and Jonathan A. Leighton -- NSAIDS, radiation and foriegn bodies / Neal J. Schamberg and Felice Schnoll-Sussman -- Vascular abnormalities of the small bowel / Warwick Selby -- Benign and malignant tumors of the small bowel / Blair S. Lewis -- Malabsorption / Peter H.R. Green and Moshe Rubin -- Small bowel transplantation and graft versus host disease / Roberto de Franchis ... [et al.] -- Capsule endoscopy in the stomach and colon / Virender K. Sharma -- Esophageal capsule endoscopy / Glenn M. Eisen.
  • ScienceDirect
    edited by Willis A. Wood.
    Also available: Print – 1982
  • ScienceDirect
    edited by Willis A. Wood.
    Also available: Print – 1982
  • 2012 Springer Protocols
    edited by Yann Chevolot.
    Recent advances and future challenges in glycan microarray technology / José L. de Paz and Peter H. Seeberger -- Chemical synthesis of carbohydrates and their surface immobilization : a brief introduction / Daniel B. Werz -- General consideration on sialic acid chemistry / Hongzhi Cao and Xi Chen -- Synthesis of azido-functionalized carbohydrates for the design of glycoconjugates / Sami Cecioni [and others] -- Polypyrrole-oligosaccharide microarray for the measurement of biomolecular interactions by surface plasmon resonance imaging / Julia Bartoli, André Roget, and Thierry Livache -- Glycosylated self-assembled monolayers for arrays and surface analysis / Fang Cheng and Daniel M. Ratner -- Carbohydrate microarrays for enzymatic reactions and quantification of binding affinities for glycan-protein interactions / Myung-Ryul Lee, Sungjin Park, and Injae Shin -- Neoglycolipid-based oligosaccharide microarray system : preparation of NGLs and their noncovalent immobilization on nitrocellulose-coated glass slides for microarray analyses / Yan Liu [and others] -- Preparation of a mannose-6-phosphate glycan microarray through fluorescent derivatization, phosphorylation, and immobilization of natural high-mannose N-glycans and application in ligand identification of P-type lectins / Xuezheng Song [and others] -- Production of fluorous-based microarrays with uncharged carbohydrates / Sahana K. Nagapayya and Nicola L.B. Pohl -- General procedure for the synthesis of neoglycoproteins and immobilization on epoxide-modified glass slides / Yalong Zhang and Jeffrey C. Gildersleeve -- Immobilization of polyacrylamide-based glycoconjugates on solid phase in immunosorbent assays / Oxana E. Galanina [and others] -- Surface plasmon resonance imaging analysis of protein binding to a sialoside-based carbohydrate microarray / Matthew J. Linman [and others] -- Glycoarray by DNA-directed immobilization / Franc̦ois Morvan [and others] -- Fabrication of carbohydrate surfaces by using non-derivatised oligosaccharides / Jonathan Popplewell [and others] -- Polysaccharide microarrays : application to the identification of heparan sulphate mimetics / Julien Dheur [and others] -- Carbohydrate antigen microarrays / Denong Wang -- Probing virus-glycan interactions using glycan microarrays / Jamie Heimburg-Molinaro [and others] -- MALDI-ToF MS analysis of glycosyltransferase activities on gold surface arrays / Nicolas Laurent [and others] -- Microarray technology using glycans extracted from natural sources for serum antibody fluorescent detection / Emanuela Lonardi [and others] -- Studying modification of aminoglycoside antibiotics by resistance-causing enzymes via microarray / Matthew D. Disney -- Microarray method for the rapid detection of glycosaminoglycan-protein interactions / Claude J. Rogers and Linda C. Hsieh-Wilson -- Neoglycolipid-based "designer" oligosaccharide microarrays to define [beta]-glucan ligands for Dectin-1 / Angelina S. Palma [and others] -- Measurement of antibodies to pneumococcal polysaccharides with luminex xMAP microsphere-based liquid arrays / Jerry W. Pickering and Harry R. Hill -- Carbohydrate microarrays in 96-well polystyrene microtiter plates / Jean-Philippe Ebran, Nabil Dendane, and Oleg Melnyk -- Photoimmobilization of saccharides / Gregory T. Carroll and Denong Wang -- Microwave-assisted method for fabrication of carbohydrate cluster microarrays on 3-dimensional hydrazide-dendrimer substrate / Xichun Zhou, Jian Zhang, and Denong Wang -- Combinatorial glycoarray / Simon Rinaldi, Kathryn M. Brennan, and Hugh J. Willison.
  • 2003 Wiley
    Chi-Huey Wong (ed.).
    ch. 1. Synthetic methodologies / Chikako Saotome, Osamu Kanie -- ch. 2. Complex carbohydrate synthesis / Makoto Kiso, Hideharu Ishida, Hiromune Ando -- ch. 3. The chemistry of sialic acid / Geert-Jan Boons, Alexei V. Demchenko -- ch. 4. Solid-phase oligosaccharide synthesis / Peter H. Seeberger -- ch. 5. Solution and polymer-supported synthesis of carbohydrates / Shin-Ichiro Nishimura -- ch. 6. Enzymatic synthesis of oligosaccharides / Jianbo Zhang, Jun Shao, Prezemk Kowal, Peng George Wang -- ch. 7. Glycopeptides and glycoproteins : synthetic chemistry and biology / Oliver Seitz -- ch. 8. Synthesis of complex carbohydrates : Everninomicin 13,384-1 / K. C. Nicolaou, Helen J. Mitchell, Scott A. Snyder -- ch. 9. Chemical synthesis of asparagine-linked glycoprotein oligosaccharides : recent examples / Yukishige Ito, Ichiro Matsuo -- ch. 10. Chemistry and biochemistry of asparagine-linked protein glycosylation / Barbara Imperiali, Vincent W.-F. Tai -- ch. 11. Conformational analysis of C-glycosides and related compounds : programming conformational profiles of C- and O-glycosides / Peter G. Goekjian, Alexander Wei, Yoshito Kishi -- ch. 12. Synthetic lipid A antagonists for sepsis treatment / William J. Christ, Lynn D. Hawkins, Michael D. Lewis, Yoshito Kishi -- ch. 13. Polysialic acid vaccines / Harold J. Jennings -- ch. 14. Synthetic carbohydrate-based vaccines / Stacy J. Keding, Samuel J. Danishefsky -- ch. 15. Chemistry, biochemistry, and pharmaceutical potentials of glycosaminoglycans and related saccharides / Tasneem Islam, Robert J. Linhardt -- ch. 16. A new generation of antithrombotics based on synthetic oligosaccharides / Maurice Petitou, Jean-Marc Herbert -- ch. 17. Sequencing of oligosaccharides and glycoproteins / Stuart M. Haslam, Kay-Hooi Khoo, Anne Dell -- ch. 18. Preparation of heterocyclic 2-deoxystreptamine aminoglycoside analogues and characterization of their interaction with RNAs by use of electrospray ionization mass spectrometry / Richard H. Griffey, Steven A. Hofstadler, Eric E. Swayze -- ch. 19. Glycosylation analysis of a recombinant P-selectin antagonist by high-pH anion-exchange chromatography with pulsed electrochemical detection (HPAEC/PED) / Mark R. Hardy, Richard J. Cornell -- ch. 20. Analytical techniques for the characterization and sequencing of glycosaminoglycans / Ram Sasisekharan, Zachary Shriver, Mallik Sundaram, Ganesh Venkataraman -- ch. 21. Thermodynamic models of the multivalency effect / Pavel I. Kitov, David R. Bundle -- ch. 22. Synthetic multivalent carbohydrate ligands as effectors or inhibitors of biological processes / Laura L. Kiessling, Jason K. Pontrello, Michael C. Schuster -- ch. 23. Glycosyltransferase inhibitors / Karl-Heinz Jung, Richard R. Schmidt -- ch. 24. RNA-aminoglycoside interactions / Haim Weizman, Yitzhak Tor -- ch. 25. Glycosylated natural products / Jon S. Thorson, Thomas Vogt -- ch. 26. Novel enzymatic mechanisms in the biosynthesis of unusual sugars / Alexander Wong, Xuemei He, Hung-Wen Liu -- ch. 27. Neoglycolipids : identification of functional carbohydrate epitopes / Ten Feizi, Alexander M. Lawson, Wengang Chai -- ch. 28. A preamble to aglycone reconstruction for membrane-presented glycolipid mimics / Murugesapillai Mylvaganam, Clifford A. Lingwood -- ch. 29. Small molecule inhibitors of the sulfotransferases / Dawn E. Verdugo, Lars C. Pedersen, Carolyn R. Bertozzi -- ch. 30. Carbohydrate-based treatment of cancer metastasis / Reiji Kannagi -- ch. 31. N-acetylneuraminic acid derivatives and mimetics as anti-influenza agents / Robin Thomson, Mark Von Itzstein -- ch. 32. Modified and modifying sugars as a new tool for the development of therapeutic agents : the biochemically engineered N-acyl side chain of sialic acid : biological implications and possible uses in medicine / Rüdiger Horstkorte, Oliver T. Keppler, Werner Reutter -- ch.33 . Modified and modifying sugars as a new tool for the development of therapeutic agents : glycosidated phospholipids as a new type of antiproliferative agents / Kerstin Danker, Annette Fischer, Werner Reutter -- ch. 34. Glycoside primers and inhibitors of glycosylation / Jillian R. Brown, Mark M. Fuster, Jeffrey D. Esko -- ch. 35. Carbohydrate-based drug discovery in the battle against bacterial infections : new opportunities arising from programmable one-pot oligosaccharide synthesis / Thomas K. Ritter, Prof. Dr. Chi-Huey Wong.
  • 2015 Springer Protocols
    edited by Bernd Lepenies.
    Carbohydrate-based vaccines : an overview / Julia Hütter and Bernd Lepenies -- Glycans as vaccine antigens and adjuvants : immunological considerations / Stephanie Zimmermann and Bernd Lepenies -- Glycan array platform as a tool to identify carbohydrate antigens / Li Xia and Jeffrey C. Gildersleeve -- Antibody-carbohydrate recognition from docked ensembles using the AutoMap procedure / Tamir Dingjan, Mark Agostino, Paul A. Ramsland, and Elizabeth Yuriev -- Generation of monoclonal antibodies against defined oligosaccharide antigens / Felix Broecker, Chakkumkal Anish, and Peter H. Seeberger -- Murine whole-blood opsonophagocytosis assay to evaluate protection by antibodies raised against encapsulated extracellular bacteria / Guillaume Goyette-Desjardins, René Roy, and Mariela Segura -- Determination of N-linked glycosylation in viral glycoproteins by negative ion mass spectrometry and ion mobility / David Bitto, David J. Harvey, Steinar Halldorsson, Katie J. Doores, Laura K. Pritchard, Juha T. Huiskonen, Thomas A. Bowden, and Max Crispin -- N-glycosylation fingerprinting of viral glycoproteins by xCGE-LIF / René Hennig, Erdmann Rapp, Robert Kottler, Samanta Cajic, Matthias Borowiak, and Udo Reichl -- Temporary conversion of protein amino groups to azides : a synthetic strategy for glycoconjugate vaccines / Tomasz Lipinski and David R. Bundle -- Gold nanoparticles as carriers for synthetic glycoconjugate vaccines / Fabrizio Chiodo and Marco Marradi -- Identification and characterization of carbohydrate-based adjuvants / Timo Johannssen and Bernd Lepenies -- Characterization of carbohydrate vaccines by NMR spectroscopy / Francesco Berti and Neil Ravenscroft -- Characterization of capsular polysaccharides and their glycoconjugates by hydrodynamic methods / Stephen E. Harding, Ali Saber Abdelhameed, Richard B. Gillis, Gordon A. Morris, and Gary G. Adams -- Glycoconjugate vaccines : the regulatory framework / Christopher Jones.
  • 2012 CRCnetBASE
    edited by Peter Grunwald.
    1. Basics in carbohydrate chemistry / Heinrich Hühnerfuss -- 2. Glycoconjugates : a brief overview / Peter Grunwald -- 3. Oligosaccharides and glycoconjugates in recognition processes / Thisbe K. Lindhorst -- 4. Glycoside hydrolases / Motomitsu Kitaoka -- 5. Disaccharide phosphorylases : mechanistic diversity and application in the glycosciences / Christiane Luley-Goedl and Bernd Nidetzky -- 6. Enzymatic and chemoenzymatic synthesis of nucleotide sugars : novel enzymes, novel substrates, novel products, and novel routes / Leonie Engels and Lothar Elling -- 7. Iteratively acting glycosyltransferases / Marta Luzhetska and Andreas Bechthold -- 8. Bacterial glycosyltransferases involved in molecular mimicry of mammalian glycans / Warren Wakarchuk -- 9. Sulfotransferases and sulfatases : sulfate modification of carbohydrates / Eli Chapman and Sarah R. Hanson -- 10. Glycosylation in health and disease / Peter Grunwald -- 11. Sialic acid derivatives, analogues, and mimetics as biological probes and inhibitors of sialic acid recognizing proteins / Joe Tiralongo and Thomas Haselhorst -- 12. Enzymes of the carbohydrate metabolism and catabolism for chemoenzymatic syntheses of complex oligosaccharides / Julian Thimm and Joachim Thiem -- 13. From gene to product : tailor-made oligosaccharides and polysaccharides by enzyme and substrate engineering / Jürgen Seibel -- 14. Synthesis and modification of carbohydrates via metabolic pathway engineering in microorganisms / Xian-wei Liu ... [et al.] -- 15. Metabolic pathway engineering for hyaluronic acid production / Esteban Marcellin, Wendy Y. Chen, and Lars K. Nielsen -- 16. Microbial rhamnolipids / Markus M. Müller ... [et al.] -- 17. Chitin-converting enzymes / Karin Moss ... [et al.] -- 18. Linear and cyclic oligosaccharides / Hajime Taniguchi -- 19. Fungal degradation of plant oligo- and polysaccharides / Ronald P. de Vries ... [et al.] -- 20. Bacterial strategies for plant cell degradation and their genomic information / Yutaka Tamaru and Roy H. Doi -- 21. Design of efficient multienzymatic reactions for cellulosic biomass processing / Anne S. Meyer.
  • 2006 CRCnetBASE
    edited by Ann-Charlotte Eliasson.
  • 2010 IARC
    Carbon Black -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale -- -- Titaniium Dioxide -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale -- -- Talc Not Containing Asbestiform Fibres -- 1. Exposure data -- 2. Studies of cancer in humans -- 3. Studies of cancer in experimental animals -- 4. Mechanistic and other relevant data -- 5. Summary of data reported -- 6. Evaluation and rationale.
    Also available: Print – 2010
  • 2007
    edited by Kyung J. Cho, Irvin F. Hawkins.
    Status: Not Checked OutLane Catalog Record
    Overview of CO2 as a contrast agent / Irvin F. Hawkins -- Physical properties and flow dynamics of CO2 / Kyung J. Cho ... [et al.] -- CO2 as a venous contrast agent : safety and tolerance / Kyung J. Cho -- Monitoring patients undergoing CO2 angiography / Grace Peterson and Kyung J. Cho -- Aortogram and runoff / Irvin F. Hawkins -- Visceral CO2 digital subtraction angiography / Kyung J. Cho -- CO2 renal digital subtraction angiography / Irvin F. Hawkins -- CO2 digital subtraction angiography for renal transplant patients / Irvin F. Hawkins -- CO2 digital subtraction angiography of tumors / Kyung J. Cho -- CO2 for traumatic bleeding / Kyung J. Cho -- CO2 for gastrointestinal bleeding / Irvin F. Hawkins -- CO2 for use in iliac arterial lower extremity percutaneous transluminal angioplasty and stent placement / Irvin F. Hawkins -- CO2 renal percutaneous transarterial angioplasty and stent placement / Irvin F. Hawkins -- CO2 upper extremity venography / Kyung J. Cho -- CO2 for wedged hepatic venography / Kyung J. Cho -- CO2 splenoportography / Irvin F. Hawkins -- CO2 with large-needle TIPS / Kyung J. Cho -- CO2 fine-needle transjugular intrahepatic portosystemic shunt / Irvin F. Hawkins -- Aneurysms, arteriovenous malformations, and arteriovenous fistula / Kyung J. Cho -- CO2 inferior vena cavography / Kyung J. Cho -- CO2 with central venous access and venous interventions / Kyung J. Cho, Aya Kamaya, and Seong T. Hahn -- CO2 guided percutaneous nephrostomies including the blunt needle technique / Irvin F. Hawkins -- CO2 plastic bag delivery system / Irvin F. Hawkins -- Potential complications and their prevention / Irvin F. Hawkins.
  • 2008 CRCnetBASE
    edited by David G. Penney.
  • 2008 CRCnetBASE
    Silvana Fiorito.
  • 2005 CRCnetBASE
    edited by M. Meyyappan.
  • 2014 Springer
    Susan C. Frost, Robert McKenna, editors.
    The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA inhibition. It was he who pointed out the importance of both the charged and uncharged character of these compounds for physiological experiments. The field of study that focuses on carbonic anhydrase (CA) has exploded in recent years with the identification.
  • 2014 Springer
    Hirohiko Tsujii, Tadashi Kamada, Toshiyuki Shirai, Koji Noda, Hiroshi Tsuji, Kumiko Karasawa, editors.
    This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.
  • 2005 CRCnetBASE
    edited by Wanda Baer-Dubowski, Agnieszka Bartoszek, Danuta Malejka-Giganti.
  • 2002 CRCnetBASE
    edited by P.N. Ravindran and K.J. Madhusoodanan.
  • 2013 Springer
    Bohuslav Ostadal, Naranjan S. Dhalla, editors.
    The processes of adaptation and maladaptation play an important role in the pathogeny of serious cardiovascular diseases, such as hypertension, valvular diseases, congenital heart disease, myocardial infarction and different cardiomyopathies as well as during adaptation to exercise and high altitude hypoxia. This volume incorporates the rapidly developing basic and clinically relevant information on adaptive mechanisms, thereby contributing to the better understanding of possible prevention and therapy of life-threatening cardiovascular diseases. The first section of this volume focuses on developmental aspects of cardiac adaptation, including chapters on comparative and molecular aspects of cardiac development, prenatal and postnatal developments, coronary vascular development, and ontogenetic adaptation to hypoxia, as well as cardiac and arterial adaptation during aging. The second section is devoted to cardiac adaptations to overload on the heart, centered around the mechanisms of cardiac hypertrophy due to pressure overload, volume overload, exercise, gender difference, high altitude, and different pathological situations. The third section of this volume highlights the roles of sympathetic nervous system with respect to [alpha]-adrenoceptor and [beta]-adrenoceptor mechanisms in the development of cardiac hypertrophy. Cardiac Adaptations will be of great value to cardiovascular investigators, who will find this book highly useful in their cardiovascular studies for finding solutions in diverse pathological conditions; it will also appeal to students, fellows, scientists, and clinicians interested in cardiovascular abnormalities.
  • 2006 Springer
    edited by Antonio Raviele.
  • 2014 Springer
    A.S. Kibos, Bradley P. Knight, Vidal Essebag, Steven B. Fishberger, Mark Slevin, Ion C. Tintoiu, editors.
    The past 50 years have witnessed the growth and evolution of clinical electrophysiology from a field whose goals were simply to understand of the mechanisms of arrhythmia to one of significant therapeutic impact. The development and refinement of implantable devices and catheter ablation have made non-pharmacological therapy a treatment of choice for most arrhythmias encountered in clinical practice. Cardiac Arrhythmias: From Basic Mechanism To State-of-the-Art Management provides an electrophysiologic approach to arrhythmias predicated on the hypothesis that a better understanding of the mechanisms of arrhythmias will lead to more successful and rationally chosen therapy. It encompasses the anatomy of arrhythmias, diagnostic methods, comorbid diseases, and the treatment of all forms of cardiac arrhythmias. It discusses modern ablation and mapping techniques, while reviews the methodology required to define the mechanism and site of origin of arrhythmias, so that safe and effective therapy can be chosen. It will thus be of interest to all involved in the management of these patients, from clinical cardiac electrophysiologists themselves to clinical cardiologists, interventionalists, cardiac surgeons, emergency medicine physicians and researchers in basic cardiac science.
  • 2009 Springer
    edited by Igor R. Efimov, Mark W. Kroll, Patrick J. Tchou.
  • 2010 ClinicalKey
    Michael Ragosta.
    Patient evaluation -- Vascular access and hemostasis -- Complications of cardiac catheterization -- Right and left heart catheterization : Pt. 1. Performance of right and left heart catheterization -- Right and left heart catheterization : Pt. 2. Collecting and analyzing hemodynamic data -- Classic hemodynamic waveforms in common pathologic conditions -- Left ventriculography -- Aortography -- Right ventriculography and pulmonary angiography -- Basic coronary angiography -- Ischemic heart disease : coronary physiology and manifestations of coronary atherosclerosis -- Ischemic heart disease : bypass graft angiography -- Advanced coronary angiography -- Coronary anomalies -- Support devices -- Pericardiocentesis and balloon pericardial window -- Endomyocardial biopsy -- Evaluation of prosthetic heart valves.
  • 2015 Springer
    Gianfranco Butera, Massimo Chessa, Andreas Eicken, John Thomson, editors ; forewords by Shakeel Qureshi and Mario Carminati.
    Congenital cardiology continues to advance at a rapid pace, with recent decades witnessing exceptional growth in the number and range of catheter-based interventions. This handbook is an ideal, up-to-date guide to the application of these procedures across the entire patient age range, from fetal life through to adulthood. Clear instruction is offered on techniques of vascular access, valve dilatation, angioplasty, stent implantation, defect closure, defect creation, pulmonary valve implantation, and the hybrid approach, as well as miscellaneous other procedures. Topics are approached using a step-by-step format, ensuring that the reader will immediately be able to access information relevant to daily practice. Many explanatory figures and drawings are included in each chapter in order to clarify further how to plan, perform, and evaluate diagnostic and interventional procedures in the field of congenital heart disease. Attention is drawn to important tips and tricks that will assist in achieving optimal outcomes. Besides the detailed descriptions of procedures, background information is provided on patient preparation, anesthesia, instrumentation, and hemodynamics. At the end of the book, an appendix includes additional general equations and BSA and oxygen consumption charts. This handbook will be an invaluable tool and a comprehensive companion for all who work in the field of congenital heart disease.
  • 2016 ClinicalKey
    [edited by] Morton J. Kern, Paul Sorajja, Michael J. Lim.
    This unique, easy-to-access handbook returns with enhanced coverage and clear instructions on what to expect, what to avoid, and how to manage complications in the cath lab. Ideal for cardiologists who need a quick clinical primer on cardiac catheterization, it offers easy access to information on the latest diagnostic and treatment advances necessary for optimal patient care. Straightforward, easy-to-understand approach and pocket-sized format are ideal for reference on the go. Covers vascular closure devices, radial artery catheterization, congenital heart disease, and drug-coated, carotid,
  • 2002 Springer Protocols
    edited by Joseph M. Metzger.
  • 2014 Springer
    Farhood Saremi, editor.
    This book is a state-of-the art reference that presents computed tomography (CT) and magnetic resonance (MR) cardiac imaging for the diagnosis and treatment planning of adult congenital heart disease (ACHD). It highlights the advantages of CT and MR in the management of ACHD, focusing on the complementary collaboration between these two modalities where possible. CT and MR aids in the evaluation of cardiac anatomy and function, leading to the demonstration of the full spectrum of abnormalities in complex cardiac malformations and the discovery of anomalous pathologies missed by other imaging techniques.
  • 2015 Springer
    Robert Pelberg.
  • 2010 Springer
    Matthew J. Budoff, Jerold S. Shinbane, editors.
    CT has long been considered an accurate technique in the assessment of cardiac structure and function, but advances in computing power and scanning technology have resulted in its increasing popularity. This book collates all relevant imaging findings of the use of cardiac CT and presents them in a relevant and practical manner.
  • 2006 Springer
    Matthew J. Budoff and Jerold S. Shinbane, editors ; associate editors, Stephan Achenbach, Paolo Raggi, and John A. Rumberger.
  • 2016 Springer
    Matthew Budoff and Jerold Shinbane, editors.
    This book collates the current knowledge in cardiovascular CT and presents this in a clinically relevant and practical format appropriate for all who use the modality. The field has experienced continued rapid evolution due to advances in technology, the expanded spectrum of cardiovascular applications and significant growth in published data. As increasing numbers have access to CT scanners, Cardiac CT Imaging: Diagnosis of Cardiovascular Disease, Third Edition provides all the relevant information on the use of this modality. This extensive revision of this well-respected textbook brings the reader up-to-date with the technique, with chapters supplied by an experienced set of contributing authors and representing the full spectrum of cardiac CT. It thus represents an essential purchase for those preparing for board examinations, all training to use this modality, and those already using cardiovascular CT on a day-to-day basis who want to stay current.
  • 2014 CRCnetBASE
    edited by Paul Schoenhagen, Carl J. Schultz, Sandra S. Halliburton.
    "Since the first publication of this book, the use of cardiovascular CT imaging has increased exponentially. This revised and updated edition captures these advances in CT scanner technology and clinical experience. Combining the experience of leading cardiovascular imaging groups in North America, Europe, and Asia, this edition focuses on appropriate use and impact on clinical outcome. Maintaining its character as an understandable introduction to the field, it discusses the principles of multidetector computed tomography (MDCT) for cardiovascular applications, practical aspects of scan acquisition and interpretation, clinical indications and imaging protocols, and clinical findings of common cardiovascular disease conditions. The ebook edition is in VitalBook Bookshelf, an ebook reader which allows you to: Access the eBook online or download it to access it offline on your smartphone, tablet or PC/Mac, Search the full text of all of the eBooks that you hold on your Bookshelf for instant access to the information you need, Watch imaging video clips, Make and share notes and highlights, Copy and paste text and figures for use in your own documents and presentations, Customize your view by changing font size and layout."--Provided by publisher.
  • 2014 Springer
    Marc Dewey.
    Cardiac computed tomography (CT) has become a highly accurate diagnostic modality that continues to attract increasing attention. This extensively illustrated book aims to assist the reader in integrating cardiac CT into daily clinical practice, while also reviewing its current technical status and applications. Clear guidance is provided on the performance and interpretation of imaging using the latest technology, which offers greater coverage, better spatial resolution, and faster imaging while also providing functional information about cardiac diseases. The specific features of scanners from all four main vendors, including those that have only recently become available, are presented. Among the wide range of applications and issues discussed are coronary calcium scoring, coronary artery bypass grafts, stents, and anomalies, cardiac valves and function, congenital and acquired heart disease, and radiation exposure. Upcoming clinical uses of cardiac CT, such as hybrid imaging, preparation and follow-up after valve replacement, electrophysiology applications, myocardial perfusion and fractional flow reserve assessment, and plaque imaging, are also explored.
  • 2011 Springer
    [edited by] Marc Dewey.
    Technical and personnel requirements -- Anatomy -- CT in the context of cardiovascular diagnosis and management -- Cardiac CT in clinical practice -- Clinical indications -- Patient preparation -- Physics background and radiation exposure -- Examination and reconstruction -- Toshiba Aquilion 64 and Aquilion ONE -- Siemens Somatom Sensation and definition -- Philips Brilliance 64 and Ict -- General Electric Light Speed VCT and Discovery CT750HD -- Reading and reporting -- Coronary artery bypass grafts -- Coronary artery stents -- Coronary artery plaques -- Cardiac function -- Cardiac valves -- Coronary artery anomalies -- Congenital and acquired heart disease -- Typical clinical examples -- Results of clinical studies -- Outlook.
  • 2011
    Calvin Tyi Hang.
    The heart is the first organ to function in development and continues to beat for seventy or more years in an adult's life. Cardiogenesis therefore is no simple task; genes have to be precisely regulated to meet the needs of a developing heart. ATP-dependent chromatin remodeling provides an important mechanism to regulate gene expression. Specifically, Brg1-associated factor, or the BAF, complexes, are crucial in heart development. Endocardial Brg1 represses the expression of a metalloproteinase, ADAMTS1, in order to allow sufficient cardiac jelly expansion for trabecular development. In addition, Brg1 functions in the myocardium to repress VEGFA to prevent the ectopic formation of coronary vasculature from the epicardium in a non-cell autonomous manner. And lastly, Brg1 serves as a bridge linking embryonic development and adult cardiomyopathies. Brg1 functions in the myocardium to keep the cardiomyocytes in a proliferating state through promoting BMP10 and repressing a cyclin-dependent kinase inhibitor p57kip2. Without Brg1, cardiomyocytes cease cell division, mature, and express adult form of myosin heavy (MHC) chain gene. Brg1 is normally turned off in adult life; however, following cardiac stress it is reactivated and turns on embryonic fetal program characterized by re-induction of embryonic MHC expression. Preventing Brg1 re-expression can repress cardiac hypertrophy and restore adult MHC expression. Furthermore, Brg1 physically interacts with other chromatin remodeling enzymes such as histone deacetylases and poly-ADP ribose polymerases to control expression of MHC genes and regulate cardiomyocyte differentiation. In all, ATP-dependent chromatin remodeling plays important roles in heart development and disease and may provide a suitable therapeutic target for human cardiomyopathies in the future.
  • 2007 Springer
    by M. Gabriel Khan.
    Also available: Print – 2007
  • 2015 Springer
    M. Gabriel Khan.
    This book is an essential guide to the medical treatment of the cardiac patient and presents core principles of cardiovascular therapeutics as well as drug recommendations. Major classes of drugs are featured, including beta-blockers, ACE inhibitors, calcium antagonists, diuretics, and antiplatelet agents and unique insights into the controversies surrounding the use of specific drugs are explored, with answers given to the question: do beta blockers and diuretics really cause diabetes? Properties, dosage, side effects, potential salutary benefits, and drawbacks on virtually all commercially available cardiac drugs are examined. This revised edition is thoroughly updated and addresses the entire spectrum of heart disorders, such as hypertension, angina, myocardial infarction, heart failure, arrhythmias, cardiac arrest, and dyslipidemias. New chapters include endocrine heart diseases, management of cardiomyopathies, and newer agents. In addition, topics such as cardiac drugs in pregnancy and lactation and drug interactions are covered. Cardiac Drug Therapy, Eighth Edition, is an authoritative and clinically relevant resource for cardiologists, cardiology fellows, and internists.
  • 2014 Springer
    Karen Sliwa, John Anthony, editors.
    In the western world, the risk of cardiovascular disease in pregnancy has grown due to the increasing age at the first pregnancy and the worldwide obesity epidemic leading to early diabetes and hypertension. As a result more women are requiring drug therapy during pregnancy and some data has shown an altered pharmacodynamic profile in pregnant women when compared to the non-pregnant population. Cardiac Drugs in Pregnancy presents up-to-date research for the treatment of cardiovascular disease during pregnancy, and discusses the most important indications of drug usage in pregnancy and postpartum. The book aims to assess the potential risk of drugs and their possible benefit against each other, making it an essential read for a wide range of health professionals involved in cardiac drug therapy in pregnancy.
  • 2011 Springer
    Andrea Natale, Amin Al-Ahmad, Paul J. Wang, John P. DiMarco (editors).
  • 2014 ScienceDirect
    2014 ClinicalKey
    [edited by] Douglas P. Zipes, Jose Jalife.
    Cardiac Electrophysiology: From Cell to Bedside puts the latest knowledge in this subspecialty at your fingertips, giving you a well-rounded, expert grasp of every cardiac electrophysiology issue that affects your patient management. Drs. Zipes, Jalife, and a host of other world leaders in cardiac electrophysiology use a comprehensive, multidisciplinary approach to guide you through all of the most recent cardiac drugs, techniques, and technologies. Get well-rounded, expert views of every cardiac electrophysiology issue that affects your patient management from preeminent authorities in cardiology, physiology, pharmacology, pediatrics, biophysics, pathology, cardiothoracic surgery, and biomedical engineering from around the world.Visually grasp and easily absorb complex concepts through an attractive full-color design featuring color photos, tables, flow charts, ECGs, and more!
  • 2010 Springer
    edited by Daniel C. Sigg, Paul A. Iaizzo, Yong-Fu Xiao, Bin He.
    Basic cardiac electrophysiology: excitable membranes -- Cardiac action potentials, ion channels, and gap junctions -- Anatomy and physiology of the cardiac conduction system -- The electrocardiogram and clinical cardiac electrophysiology -- Clinical cardiac electrophysiology : an overview of its evolution -- Principles of electrophysiological in vitro measurements -- Cardiac cellular electrophysiological modeling -- Computer modeling of electrical activation : from cellular dynamics to the whole heart -- Detection and measurement of cardiac ion channels -- Cell culture models and methods -- Isolated tissue models -- Isolated heart models -- Small animal models for arrhythmia studies -- Use of large animal models for cardiac electrophysiology studies -- Optical mapping and calcium imaging -- Electrophysiology of single cardiomyocytes : patch clamp and other recording methods -- Invasive electroanatomical mapping and navigation -- Cardiac electrophysiological imaging : solving the inverse problem of electrocardiography -- Traditional electrophysiological mapping -- Multi-channel system for analysis of cardiac rhythmicity and conductivity in vitro -- Cardiac CT/MRI imaging for electrophysiology -- Introduction to translational research -- Clinical perspective : electrophysiology in the young and patients with congenital heart disease.
  • 2014 Springer
    Gary D Lopaschuk and Naranjan S. Shalla, editors.
    Part I. Control of Energy Metabolism -- A Primer on Carbohydrate Metabolism in the Heart / Heinrich Taegtmeyer -- Lipoproteins: A Source of Cardiac Lipids / Konstantinos Drosatos and Ira J. Goldberg -- Role of Lipoprotein Lipase in Fatty Acid Delivery to the Heart / Andrea Wan and Brian Rodrigues -- Control of Myocardial Fatty Acid Uptake / Jan F. C. Glatz and Joost J. F. P. Luiken -- Cardiac Energy Metabolism in Heart Failure Associated with Obesity and Diabetes / Gary D. Lopaschuk -- Transcriptional Control of Mitochondrial Biogenesis and Maturation / Rick B. Vega , Teresa C. Leone , and Daniel P. Kelly -- Relationship Between Substrate Metabolism and Cardiac Efficiency / Ellen Aasum -- Acetylation in the Control of Mitochondrial Metabolism and Integrity / Michael N. Sack -- Part II. Alteration in Energy Metabolism -- Adrenergic Control of Cardiac Fatty Acid Oxidation in Diabetes / Vijay Sharma and John H. McNeill -- The Myocardial Creatine Kinase System in the Normal, Ischaemic and Failing Heart / Craig A. Lygate and Stefan Neubauer -- Fuel Metabolism Plasticity in Pathological Cardiac Hypertrophy and Failure / Stephen C. Kolwicz and Rong Tian -- Defects in Mitochondrial Oxidative Phosphorylation in Hearts Subjected to Ischemia-Reperfusion Injury / Vijayan Elimban , Paramjit S. Tappia , and Naranjan S. Dhalla -- The Role of AMPK in the Control of Cardiac Hypertrophy / Nikole J. Byrne, Miranda M. Sung, and Jason R. B. Dyck -- The Role of Incomplete Fatty Acid β-Oxidation in the Development of Cardiac Insulin Resistance / John R. Ussher -- Part III. Optimization of Energy Metabolism -- Metabolic Therapy for the Ischemic Heart / Giacinta Guarini , Alda Huqi , and Mario Marzilli -- Inhibition of Fatty Acid Oxidation to Treat Heart Failure in Patients / Rui Yan , Jin Wei , and Dengfeng Gao -- Cardiac Metabolic Protection for the Newborn Heart / J. Carter Ralphe and Thomas D. Scholz -- Targeting Transcriptional Control of Fatty Acid Oxidation to Treat Heart Disease / Michael A. Portman and Aaron K. Olson.
  • 2015 Springer
    Ian M.C. Dixon, Jeffrey T. Wigle, editors.
    Cardiac fibrosis and heart failure-- cause or effect? -- Fibroblast activation in the infarcted myocardium -- Mechanical and matrix regulation of valvular fibrosis -- Bone marrow-derived progenitor cells, micro-RNA, and fibrosis -- The stressful life of cardiac myofibroblasts -- Pathogenic origins of fibrosis in the hypertensive heart disease that accompnaies aldosternoism -- Embryological origin of valve progenitor cells -- Diverse cellular origin of valve progenitor cells -- Diverse cellular origins of cardiac fibroblasts -- Non-canonical regulation of TGF-β1 signaling: a role for Ski/Sno and YAP/TAZ -- Molecular mechanisms of smooth muscle and fibroblast phenotype conversions in the failing heart -- Current and future strategies for the diagnosis and treatment of cardiac fibrosis -- Remodelling of the cardiac extracellular matrix: role of collagen degradation and accumulation in pathogenesis of heart failure -- Matrix metalloproteinase 9 (MMP-9) -- Collagen processing and its role in fibrosis -- Mechanisms of cardiac fibrosis and heart failure -- Mathematical simulations of sphingosine-1-phosphate actions on mammalian ventricular myofibroblasts and myocytes -- Extracellular matrix and cardiac disease: surgical and scientific perspectives -- The role or neurohumoral activation in cardiac fibrosis and heart failure -- Natriuretic peptides: critical regulators of cardiac fibroblasts and the extracellular matrix in the heart -- Cardiac tissue engineering for the treatment of heart failure post-infarction -- Mechanisms in cardiac valve failure and the development of tissue engineered heart valves -- Index.
  • 2007 Springer Protocols
    edited by Jun Zhang and Gregg Rokosh.
  • 19??.
    issued by the Scientific Department of the Sandoz Chemical Works.
  • 2008 Thieme
    Claus D. Claussen, Stephan Miller, Reimer Riessen, Michael Fenchel, Ulrich Kramer.
    Ischemic heart disease / S. Miller, U. Kramer -- Heart failure / R. Riessen -- Acquired valvular heart diseases / U. Kramer -- Cardiomyopathy / S. Miller -- Inflammatory heart diseases / S. Miller -- Hypertension / R. Riessen -- Tumors and other masses / M. Fenchel -- Trauma / U. Kramer -- Congenital heart diseases / M. Fenchel -- Diseases of the great vessels / U. Kramer -- Standard planes of section / S. Miller.
  • 2010 Thieme Book
    edited by Carlos Santiago Restrepo, Dianna M. E. Bardo.
    RadCases contains cases selected to simulate everything that you'll see on your rounds, rotations, and exams. RadCases also helps you identify the correct differential diagnosis for each case - including the most critical. RadCases covers: Cardiac Imaging, Interventional Radiology, Musculoskeletal Imaging, Neuro Imaging, Chest Imaging, Pediatric Imaging, Gastrointestinal Imaging, Breast Imaging, Nuclear Medicine, Ultrasound Imaging, Head and Neck Imaging, and Genitourinary Imaging.
  • c2006
    Gautham P.Reddy.
    Status: Not Checked OutLane Catalog Record
  • 2014 ClinicalKey
    Gautham P. Reddy, Robert M. Steiner, Christopher M. Walker.
    Also available: Print – 2014
  • 2009
    [edited by] Stephen Wilmot Miller, Lawrence M. Boxt, Suhny Abbara.
    Status: Not Checked OutLane Catalog Record
    Part I. Imaging Modalities -- 1. The Elements of Cardiac Imaging / Stephen Miller -- 2. Echocardiography / Mary Etta King and Kaitlyn Lam -- 3. Cardiac Magnetic Resonance Imaging / Lawrence Boxt and Amgad Makaryus -- 4. Cardiac Angiography / Stephen Miller and Anand Soni -- 5. Cardiac CT / Lawrence Boxt and Amgad Makaryus -- Part II. Specific Diseases -- 6. Valvular Heart Disease / Stephen Miller and Anand Soni -- 7. Ischemic Heart Disease / Stephen Miller -- 8. Coronary CTA / Suhny Abbara -- 9. Pericardial and Myocardial Disease / Suhny Abbara and Stephen Miller -- 10. Congenital Heart Disease / Laureen Sena, Stephen Miller, and Lawrence Boxt -- 11. Thoracic Aortic Disease / John Santilli.
  • 2009 Thieme Book
    edited by Manfred Thelen [and others] ; with contributions by N. Abegundewardene [and others].
    Conventional radiography -- Echocardiography -- Angiography -- Nuclear medicine imaging -- Computed tomography -- Magnetic resonance imaging -- Heart defects and endocarditis -- Coronary heart disease -- Cardiomyopathies and myocarditis -- Cardiac tumors -- Diseases of the pericardium -- Diseases of the great pulmonary vessels -- Diseases of the thoracic aorta.
  • Reddy, Gautham P.; Steiner, Robert M.
    Status: Not Checked OutLane Catalog Record
  • 2016 Springer
    Dmitriy Kireyev, Judy Hung, editors.
    Echocardiography-Physics basics -- Views -- Chamber quantification -- Valves: AS, AR, MS, MR, TS, TR, PS, PR subchapters -- Artificial valves basics, AS, AR, MS, MR, TS, TR, PS, PR -- Diastology -- Pericardial disease -- Cardiac Masses -- Non-invasive catheterization -- Basic cardiac anomalies -- Ischemic heart disease -- CHF -- Cardiomyopathies -- Systemic diseases -- Aortic disease -- Basics of bubble and contrast studies -- SPECT-Basics of SPECT Radioisotopes -- Ischemia work up -- Viability work up -- CT- Technique -- Indications -- Sample images -- MRI-Basic technique -- Indications -- Function, Viability -- Masses, CMP, scar, amyloid, HCM images -- Pericardium: inflammation, constriction vs. restriction.
  • 2012 Springer
    Angelo Auricchio, Jagmeet Singh, Frank E. Rademakers, editors.
    Part I. Technology Evaluation -- 1. Imaging-Based Heart Anatomy / Francesco Fulvio Faletra, Ann C. Garlitski, François Regoli, and Natesa G. Pandian -- 2. Magnetic Resonance Imaging: Description of Technology and Protocols / Gaston R. Vergara and Nassir F. Marrouche -- 3. Cardiac Computed Tomography: Description of Technology and Protocols / Quynh A. Truong, Subodh B. Joshi, and Udo Hoffmann -- 4. Nuclear-Based Imaging: Description of Technology and Protocols / Juhani Knuuti -- 5. Echocardiography: Technology and Protocols / José Zamorano and José Alberto de Agustín -- Part II. Catheter Ablation -- 6. Anatomy Assessment for Atrial Arrhythmias / Sheldon M. Singh and Andre D'Avila -- 7. Anatomical Assessment for Catheter Ablation of Ventricular Tachycardia / Paolo Della Bella, Giuseppe Maccabelli, and Corrado Carbucicchio -- 8. Intra-Procedural Techniques: Fluoroscopy and Angiography / Matthew Wright, Sébastien Knecht, and Pierre Jaïs -- 9. Intraprocedural Techniques: Transesophageal (2D/3D) and Intracardiac Echocardiography / Josef Kautzner and Petr Peichl -- 10. Intraprocedural Techniques: Angioscopy and Optical Imaging / Paul J. Wang, Amin Al-Ahmad, Henry H. Hsia, Paul C. Zei, Mintu Turakhia, Marco Perez, and Christian S. Eversull -- 11. Contact and Noncontact Electroanatomical Mapping / Narayanan Namboodiri, Anthony G. Brooks, and Prashanthan Sanders -- 12. The Role of Imaging for Catheter Ablation in the Pediatric Population / John Triedman -- Part III. Device Therapy -- 13. Substrate Assessment: Echocardiography, MRI, and CCT / Victoria Delgado, Matteo Bertini, Rutger J. van Bommel, C. Jan Willem Borleffs, Martin J. Schalij, and Jeroen J. Bax -- 14. Dyssynchrony Evaluation: Echocardiography / John Gorcsan III -- 15. Dyssynchrony Evaluation: MRI and CCT / Kenneth Bilchick, Eliot McVeigh, and Albert Lardo -- 16. Nuclear Imaging for Device Therapy / Amparo L. Figueroa and Ahmed Tawakol -- 17. Post-CRT Imaging Based Optimization / Veronica Lea J. Dimaano, Aurélio C. Pinheiro, and Theodore P. Abraham -- 18. Sudden Cardiac Risk Assessment / Stephan Danik and Jagmeet Singh -- Part IV. Advances in Navigation and Integration -- 19. MRI/CCT Fusion into Fluoroscopic Imaging / Nassir F. Marrouche and Gaston R. Vergara -- 20. Magnetic Navigation: Description of Technique, Advantages, and Technical Issues / Sabine Ernst -- 21. Magnetic and Robotic Navigation / Bruce D. Lindsay and Oussama Wazni.
  • Restrepo, Carlos.
    Status: Not Checked OutLane Catalog Record
  • 2016 ClinicalKey
    [edited by] Lawrence M. Boxt, Suhny Abbara.
    Introduction to cardiac imaging / Lawrence M. Boxt and Suhny Abbara -- Echocardiography / Kaitlyn My-Tu Lam and Mary Etta E. King -- Cardiac magnetic resonance imaging / Amgad N. Makaryus and Lawrence M. Boxt -- Cardiac computed tomography / Amgad N. Makaryus and Lawrence M. Boxt -- Coronary heart disease / Nagina Malguria and Suhny Abbara -- Myocardium, pericardium, and cardiac tumor / Nagina Malguria, Stephen W. Miller, and Suhny Abbara -- Valvular heart disease / Suhny Abbara and Nagina Malguria -- Thoracic aortic disease / Steven L. Hsu, Sanjeeva Kalva, John G. Santilli, and Stephen W. Miller -- Congenital heart disease / B. Kelly Han, Stephen W. Miller, and Lawrence M. Boxt.
  • 2010 ClinicalKey
    [edited by] Allen Jeremias, David L. Brown.
    The new edition of Cardiac Intensive Care--the only textbook dedicated to cardiac intensive care medicine--chronicles the progress made in the diagnosis, assessment, and treatment of patients with critical cardiac illness. Editors Allen Jeremias, MD, MSc and David L. Brown, MD present the landmark discoveries, greater understanding of syndromes, and technological advancements that have helped make clinical cardiology a progressive and interventional field. You'll get coverage of the plethora of noncoronary diseases in the CICU, as well as a complete compendium of up-to-date pharmacologic agents. The new full-color design and layout and nine new chapters give you the latest theoretical, technical, diagnostic, and therapeutic advances in an accessible and visually appealing format. Moreover, the full text is available online at expertconsult.com. Features the authoritative perspectives of a stellar group of contributors - many of whom are the pioneers in the fields they cover - for the best available guidance. Provides the basic science framework for the clinical material through a section on the scientific foundation of cardiac intensive care to give you the complete picture. Presents a pharmacological introduction to the classes of drugs so you know which are most commonly used in the CICU. Covers which noncoronary diseases frequently result in admittance to the CICU to prepare you for those diagnoses that are not of a cardiac nature.
  • 2013 Springer
    Ganga Karunamuni, editor.
    Anatomy of the Cardiac Lymphatic System. A General Outline of the Cardiac Lymphatic System / Marios Loukas, Sameer Shah, Shivayogi Bhusnurmath, Bharti Shivayogi Bhusnurmath -- Development and Patterning of the Cardiac Lymphatic Network / Jörg Wilting, Jörg Männer -- The Cardiac Lymphatics and Heart Disease. The Link Between Lymphatic Obstruction and Congenital Heart Disease / Manish Bansal -- The Role of Lymphatics in Atherogenesis, Myocardial Infarction, Congestive Heart Failure, and Cardiac Transplantation / Shin Lin, Stanley G. Rockson -- The Lymphatics in Normal and Pathological Heart Valves / Ivana Kholová, Galina Dragneva, Seppo Ylä-Herttuala -- Therapeutic Applications Targeting the Cardiac Lymphatics in Heart Disease / Jae-Hyeong Park, Jin-Ok Jeong -- Imaging the Lymphatic System in Heart Transplantation and Its Immunological Implications / Kathryn Brown, Lindsey A. Edwards, Wilson Wong -- Cardiac Lymphatic Signaling. Tie Receptor Signaling in Cardiac Lymphangiogenesis / Xianghu Qu, H. Scott Baldwin -- VEGF Receptor Signaling in the Cardiac Lymphatics / Alexey Dashkevich, Karl B. Lemström, Antti I. Nykänen -- Hypoxia and the Cardiac Lymphatic System / Todd R. Wuest, P. Charles Lin -- The Potential of the Epicardium to Act as a Source of Lymphatic Cells / Linda Klotz, Paul Riley.
  • 2015 Springer
    Gonzalo Baron Esquivias, Riccardo Asteggiano, editors.
    Introduction -- Physiopathology and toxic drugs heart effects -- Radiotherapy heart effects -- Cardiac imaging technology in cardio-oncology -- Evaluation of the oncologic patient before, during and after chemotherapy -- What drug/what possible complication -- What cancer type/what possible drug -- what cancer/what possible complication -- Management (prevention/diagnosis/evaluation/therapy) of hypertension -- Management (prevention/diagnosis/evaluation/therapy) of coronary disease and thrombo-embolic complication -- Management (prevention/diagnosis/evaluation/therapy) of arrhythmic complication -- Management (prevention/diagnosis/evaluation/therapy) of systolic dysfunction.
  • 2013 Wiley
    edited by Mohammad Shenasa, Gerhard Hindricks, Martin Borggrefe, Gunter Breithardt, Mark E. Josephson.
  • 2007 Springer
    [edited by] Matti Weckström, Pasi Tavi.
  • 2010 Ovid
    [edited by] Susan L. Woods ... [et al.].
    Part I. Anatomy and Physiology -- Part II. Physiologic and Pathologic Responses -- Part III. Assessment of Heart Disease -- Part IV. Pathophysiology and Management of Heart Disease -- Part V. Health Promotion and Disease Prevention.
  • 2005 Ovid
    [edited by] Susan L. Woods, Erika Sivarajan Froelicher, Sandra Adams (Underhill) Motzer, Elizabeth J. Bridges.
    Also available: Print – 2005
  • 2012 Springer
    David R. Ramsdale, Archana Rao.
    Cardiac pacing is one of the best examples where the developments in technology and the microchip industry have resulted in outstanding clinical benefits to patients, and it is likely that further innovation and miniaturization will continue to make this specialty a stimulating and exciting one. As pacing is being devolved from specialist to smaller cardiology centers and where pacemaker implantation is becoming the domain of cardiologists rather than surgeons, there is a need for practical clinical guidance to pacing issues that can be used alongside a comprehensive practical training program in an experienced pacing centre. Cardiac Pacing and Device Therapy is a practical reference for all those involved in the day-to-day care of paced patients and particularly for those cardiologists planning a career in this most interesting and exciting specialty, the so-called "device specialist". The text and images will give the reader a greater understanding of the type of technology and equipment that is currently available from the cardiac device industry. The book contains practical information on temporary and epicardial pacing, elective generator change, explant procedures, pacing in children, implantable cardioverter defibrillators, cardiac resynchronization therapy, troubleshooting in pacing and training guidelines/regulations for those intending to make a career in pacing/device implantation. As such, this book provides an superb illustrated introduction to those with an interest in cardiac pacing and device therapy, from trainees and clinical fellows through to consultant cardiologists involved in a pacemaker program, cardiac physiologists and other allied medical professionals.
  • 2013 Wiley
    edited by David L. Hayes, Samuel J. Asirvatham, Paul A. Friedman.
    As our population ages and multiple factors contribute to an increased prevalence of cardiovascular disease, more patients than ever before will be candidates for implantable devices as part of their treatment for heart rhythm abnormalities. Electrophysiologists have a widening array of sophisticated devices from which to choose, and important new data about efficacy, long-term outcomes and possible complications has emerged, impacting how devices are chosen and utilized. Overall, the management of patients with pacemakers and ICDs and other devices remains a complex topic and the need for.
  • 2008 Springer
    edited by Fred M. Kusumoto and Nora F. Goldschlager.
    Pacing leads -- The pulse generator -- Modes of pacemaker function -- Implant techniques -- Transvenous left ventricular lead implantation -- Endocardial lead extraction -- Techniques for temporary pacing -- Difibrillator function and implantation -- Sinus node dysfunction -- Acquired atrioventricular block -- Cardiac resynchronization therapy for congestive heart failure -- Pacing therapies for atrical fibrillation -- Pacemakers and syncope -- Indications for implantable cardiovascular defibrillators -- Cardiac device therapy in children -- Cardiac pacing in the critical care setting -- Environmental effects on cardiac pacing systems -- Radiography of implantable arrhythmia management devices -- Follow-up management of the paced patient -- Follow-up of the patient with an implanted cardiac defibrillator.
  • 2013 Springer
    S. Kim Suvarna, editor.
    General Considerations and Anatomy -- Cardiac Electrophysiology -- Cardiac Imaging -- Current Therapeutics for Cardiac Disease -- The Heart at Autopsy -- Embryology of the Heart -- Ischemic Heart Disease -- Myocarditis/Inflammatory Cardiomyopathy -- Valvular Heart Disease -- Transplant Pathology -- Cardiomyopathies -- Cardiac Tumors -- Congenital Heart Disease -- Sudden Cardiac Death.
  • 2007 Springer
    editors, Marcelo F. Di Carli, Martin J. Lipton.
  • 2005 Springer
    Richard A. Hopkins, Karl E. Karlson, and Gloria A. Karlson ; illustrations by Thomas Xenakis.
  • 2007 Springer
    edited by William E. Kraus and Steven J. Keteyian.
  • 2011 Springer
    [edited by] Josef Niebauer.
    General Principles of Exercise Testing in Cardiac Rehabilitation -- General Principles of Nutrition Support in Cardiac Rehabilitation -- Psychological Care of Cardiac Patients -- Exercise Training in Cardiac Rehabilitation -- Angina Pectoris -- Diabetes Mellitus Type 2 and Cardiovascular Disease -- Cardiac Rehabilitation After Acute Myocardial Infarction: The Influence of Psychosocial Disorders -- Stable Coronary Artery Disease: Exercise-Based Cardiac Rehabilitation Reduces the Risk of Recurrent Angina after PCI in the Case of Arterial Hypertension -- Rehabilitation of Patients After CABG/Sternotomy -- Congestive Heart Failure: Stable Chronic Heart Failure Patients -- Cardiac Rehabilitation in Patients with Implantable Cardioverter Defibrillator -- Exercise Training in Congenital Heart Diseases -- Pacemaker Implantation -- Patient with Peripheral Artery Disease.
  • 2013 Springer
    Bodh I. Jugdutt, Naranjan S. Dhalla, editors.
    The main objective of Cardiac Remodeling: Molecular Mechanisms is to summarize the major research advances in molecular, biochemical and translational aspects of cardiac remodeling over the last 2 to 3 decades under one cover and touch on future directions. It provides a high profile and valuable publication resource on molecular mechanisms of cardiac remodeling for both the present and future generations of researchers, teachers, students and trainees. This book should stimulate future translational research targeted towards discovery and development for preventing, limiting and reversing bad remodeling over the next few decades, with the ultimate goal of preventing progression to systolic and/or diastolic heart failure. The chapters suggest potential novel strategies that should receive attention for translating basic research knowledge to application in patients at the bedside.
  • 2005 Springer
    edited by Joel Morganroth, Ihor Gussak.
  • 2015 Springer
    Andrew M. Freeman, Howard D. Weinberger, editors.
  • 2008
    Siavosh Khonsari, Colleen Flint Sintek ; in collaboration with Abbas Ardehali ; with contribution from Ramin E. Beygui, Kwok L. Yun ; illustrator, Timothy C. Hengst.
    Status: Not Checked OutLane Catalog Record
  • 2008
    [edited by] Lawrence H. Cohn.
    Status: Not Checked OutLane Catalog Record
  • 2012 AccessSurgery
    [edited by] Lawrence H. Cohn.
  • 2012 ClinicalKey
    Donald B. Doty, John R. Doty ; with illustrations by Jill Rhead, Christy Krames.
    "Cardiac Surgery: Operative Technique, by Drs. Donald B. Doty and John R. Doty, is your essential source on how to perform today's full range of cardiac surgical techniques. Over 1,000 crisp illustrations and expert, evidence-based discussions guide you step by step, equipping you to perform all of the latest procedures and get the best outcomes."--Publisher's website.
  • 2014 Springer Protocols
    edited by Milica Radisic, Lauren D. Black III.
    Second generation codon optimized minicircle (CoMiC) for nonviral reprogramming of human adult fibroblasts / Sebastian Diecke ... [and 3 others] -- Scalable cardiac differentiation of human pluripotent stem cells as microwell-generated, size controlled three-dimensional aggregates / Celine L. Bauwens and Mark D. Ungrin -- Preparation and characterization of circulating angiogenic cells for tissue engineering applications / Aleksandra Ostojic ... [and 4 others] -- Isolation and expansion of C-kit-positive cardiac progenitor cells by magnetic cell sorting / Kristin M. French and Michael E. Davis -- Synthesis of aliphatic polyester hydrogel for cardiac tissue engineering / Sanjiv Dhingra, Richard D. Weisel, and Ren-Ke Li -- Fabrication of PEGylated fibrinogen : a versatile injectable hydrogel biomaterial / Iris Mironi-Harpaz, Alexandra Berdichevski, and Dror Seliktar -- Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes / Donald O. Freytes ... [and 4 others] -- Magnetically actuated alginate scaffold : a novel platform for promoting tissue organization and vascularization / Yulia Sapir ... [and 3 others.] -- Shrink-induced biomimetic wrinkled substrates for functional cardiac cell alignment and culture / Nicole Mendoza ... [and 4 others] -- Injectable ECM scaffolds for cardiac repair / Todd D. Johnson, Rebecca L. Braden, and Karen L. Christman -- Generation of strip-format fibrin-based engineered heart tissue (EHT) / Sebastian Schaaf ... [and 5 others.] -- Cell tri-culture for cardiac vascularization / Ayelet Lesman, Lior Gepstein, and Shulamit Levenberg -- Cell sheet technology for cardiac tissue engineering / Yuji Haraguchi ... [and 8 others] -- Design and fabrication of biological wires / Jason W. Miklas ... [and 3 others] -- Collagen-based engineered heart muscle / Malte Tiburcy ... [and 3 others] -- Creation of a bioreactor for the application of variable amplitude mechanical stimulation of fibrin gel-based engineered cardiac tissue / Kathy Y. Morgan and Lauren D. Black III -- Preparation of acellular myocardial scaffolds with well- preserved cardiomyocyte lacunae, and method for applying mechanical and electrical simulation to tissue construct / Bo Wang ... [and 3 others] -- Patch-clamp technique in ESC-derived cardiomyocytes / Jie Liu and Peter H. Backx -- Optogenetic control of cardiomyocytes via viral delivery / Christina M. Ambrosi and Emilia Entcheva -- Methods for assessing the electromechanical integration of human pluripotent stem cell-derived cardiomyocyte grafts / Wei-Zhong Zhu ... [and 3 others] -- Quantifying electrical interactions between cardiomyocytes and other cells in micropatterned cell pairs / Hung Nguyen ... [and 4 others].
  • 2013 Springer
    Cristina Basso, Marialuisa Valente, Gaetano Thiene, editors.
    Cardiac tumors were once a nosographic entity of scarce clinical interest because of the rarity and of the intrinsic diagnostic and therapeutic impossibilities, and were considered a fatal morbid entity. It has now become a topical subject due to advances in clinical imaging (echo, magnetic resonance, computed tomography) as well as innovation in technologies of in-vivo diagnosis. Cardiac Tumor Pathology presents a spectacular example of these advances with clinico-pathologic correlations. This timely volume covers history, epidemiology, demographics, clinical diagnosis, pathology, imaging by echo, CT and MRI of both benign and malignant cardiac tumors, either primary or secondary. Chemotherapy of malignant neoplasms is also addressed. Special emphasis is given to clinico-pathologic correlations. With all chapters written by experts in their fields, this volume will serve as a useful resource for physicians dealing with, and interested in, this special branch of cardiac oncology and will represent a useful guide for pathologists, clinicians, cardiologists, cardiac surgeons, and radiologists as well as for postgraduate students training in these areas.
  • 2013 Springer
    Nalini M. Rajamannan, editor.
    Experimental studies in the field of cardiac valve biology are now demonstrating that the cardiac valve disease process is an active biology with risk factors analogous to vascular risk factors. Understanding the risk factors is also evolving rapidly, giving physicians and scientists insight into the cellular mechanisms and raising the possibility of treating these valve lesions with other options besides surgical valve repair. Our knowledge of right-sided valve lesions is also rapidly becoming important in the field of valvular medicine. Not only is the pathology different from left-sided valve lesions, but the hemodynamic compromise is more complex and difficult to treat in patients who develop tricuspid or pulmonic valve disease. Early diagnosis and careful management of this patient population is critical for long term outcomes in this patient population. Cardiac Valvular Medicine represents an overview of the most recent science, clinical trials and new discoveries in the field of valvular heart disease. The editor has assembled a team of highly experienced contributors to provide a thorough translational understanding of the current and future treatments for this patient population. Cardiologists, internists, family practice physicians, cardiac surgeons and basic scientists will all find enormous benefit from this textbook.
  • 2011 Springer
    Gabriel A. Adelmann.
  • 2006 Springer
    by Steven M. Hollenberg, Tracy Walker.
    Acute coronary syndromes -- Arrhythmias -- Prevention of bacterial endocarditis -- Congestive heart failure -- Hyperlipidemia -- Hypertension -- Pericardial diseases -- Stable angina -- Valvular disease.
  • 2010 ClinicalKey
    [edited by] Michael H. Crawford, John P. DiMarco, Walter J. Paulus.
    Offers a problem-based approach that integrates basic science, diagnostic investigations, and therapeutic management in one place for each cardiovascular disease so you can quickly find all of the actionable knowledge you need without flipping from one section to another. Features introductory bulleted highlights in each chapter that present the most pertinent information at a glance. Presents abundant algorithms to expedite clinical decision making. Includes more than 2,000 illustrations, color photographs, tables, and ECGs that capture clinical manifestations as they present in practice, and promote readability and retention.
  • 2014 ScienceDirect
    2014 ClinicalKey
    [edited by] Glenn N. Levine.
    Get quick answers to the most important clinical questions with Cardiology Secrets! Using the popular and trusted Secret Series Q&A format, this easy-to-read cardiology book provides rapid access to the practical, "in-the-trenches" know-how you need to succeed both in practice, and on cardiology board and recertification exams. Get the evidence-based guidance you need to provide optimal care for your patients with cardiac heart diseases.Explore effective solutions to a full range of clinical issues including the general examination, diagnostic procedures, arrhythmias, symptoms and disease states, valvular heart disease, cardiovascular pharmacology, and other medical conditions with associated cardiac involvement.Zero in on key information with bulleted lists, mnemonics, practical tips from the leading cardiologists, and "Key Points" boxes that provide a concise overview of important board-relevant content.Review essential material efficiently with the "Top 100 Secrets in Cardiology" - perfect for last-minute study or self-assessment.
  • 2010
    [edited by] Glenn N. Levine.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer Protocols
    edited by Gary R. Skuse and Maureen C. Ferran.
    This volume has been assembled for scientists interested in basic and applied biomedical research directed toward understanding the development, genetics, and function of cardiomyocytes. The methods and protocols contained within it address cell culture techniques, cardiomyocyte differentiation and redifferentiation, experimental induction of cardiomyopathies, introducing genes into cardiomyocytes, genomic approaches to the understanding cardiomyocytes, cryopreservation of neonatal cardiomyocytes, and modeling of cardiomyocyte function. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and current, Cardiomyocytes: Methods and Protocols explores complimentary areas of cardiomyocyte science that, taken together, can inform individuals with a broad range of interests.
  • 2008
    [edited by] Glenn P. Gravlee ... [et al.].
    Status: Not Checked OutLane Catalog Record
    Historical development of cardiopulmonary bypass in Minnesota -- The birth of an idea and the development of cardiopulmonary bypass -- Blood pumps in cardiopulmonary bypass -- Principles of oxygenator functions: gas exchange, heat transfer, and operation -- Circuitry and cannulation techniques -- Ultrafiltration and dialysis -- Mechanical circulatory support devices -- Cardiopulmonary bypass for minimally invasive cardiac surgery -- Temperature management in cardiac surgery -- Myocardial protection -- Changes in the pharmacokinetics and pharmacodynamics of drugs administered during cardiopulmonary bypass -- Embolic events -- Endocrine, metabolic, and electrolyte responses -- Cardiopulmonary bypass and the lung -- Immune system and inflammatory responses to cardiopulmonary bypass -- Kidney function and cardiopulmonary bypass -- Splanchnic visceral, metabolic, and glucoregulatory effects of cardiopulmonary bypass -- Neurologic effects of cardiopulmonary bypass -- Hemodilution and priming solutions -- The blood-surface interface -- Hematologic effects and coagulopathy -- Coagulation testing -- Anticoagulation for cardiopulmonary bypass -- Heparin neutralization -- Pharmacologic prophylaxis for post-cardiopulmonary bypass bleeding -- Conduct of cardiopulmonary bypass -- Teamwork: a systems-based practice -- Primum non nocere: patient safety in cardiopulmonary bypass -- Unusual problems in cardiopulmonary bypass -- Termination of cardiopulmonary bypass -- ECMO for respiratory support in adults -- Perfusion for thoracic aortic surgery -- Noncardiac surgical applications of cardiopulmonary bypass -- Pediatric cardiopulmonary bypass overview: state of the art and future -- Myocardial protection and preservation for neonates and infants -- Brain injury following infant cardiac surgery and neuroprotective strategies -- ECMO for infants and children -- Circulatory assist devices for infants and children.
  • 2015 Cambridge
    edited by Sunit Ghosh, Florian Falter, Albert C. Perrino, Jr.
    Equipment and monitoring for cardiopulmonary bypass / Victoria Molyneux and Andrew A. Klein -- Cardiopulmonary bypass circuit setup and safety checks / Hannah Kiziltug and Simon Colah -- Priming solutions for cardiopulmonary bypass circuits / Christiana Georgiou and Joanne Irons -- Anticoagulation, coagulopathies, blood transfusion and conservation in cardiac surgery / Liza Enriquez and Linda Shore-Lesserson -- Conduct of cardiopulmonary bypass / Christiana Burt, Saran Hutton and Betsy Evans -- Metabolic management during cardiopulmonary bypass / Kevin Collins and G. Burkhard Mackensen -- Myocardial protection and cardioplegia / Maurice Hogan and David Jenkins -- Weaning from cardiopulmonary bypass / Amy Needham and Christopher P.R. Walker -- Mechanical circulatory support / Kirsty Dempster and Steven Tsui -- Deep hypothermic circulatory arrest / Joseph E. Arrowsmith and Charles W. Hogue -- Organ damage during cardiopulmonary bypass / Christopher C.C. Hudson and Sherif Assaad -- Cerebral morbidity in adult cardiac surgery / David J. Cook and Sean M. Bruggink -- Acute kidney injury (AKI) in cardiac surgery / Robert C. Albright -- Extracorporeal membrane oxygenation / Loreta Grecu -- Paediatric aspects of cardiopulmonary bypass / D.D.L. Wong and Craig R. Bailey -- Non-cardiac surgery functions of cardiopulmonary bypass / Lay Ping Ong and Sukumaran K. Nair.
  • 2005 Springer
    edited by Joseph P. Ornato, Mary Ann Peberdy.
    History of the science of cardiopulmonary resuscitation / Mickey S. Eisenberg -- Epidemiology of sudden death / Russell V. Luepker -- Prevention of sudden cardiac death / Joseph E. Marine -- Physiology of ventilation during cardiac arrest / Andrea Gabrielli, A. Joseph Layon, and Ahamed H. Idris -- Management of ventilation during resuscitation / Marsh Cuttino -- Management of airway obstruction / Michael R. Sayre -- Etiology, electrophysiology, myocardial energy mechanics, and treatment of bradyasystole / Charles E. Cady and Tom P. Aufderheide -- Pulseless electrical activity / John M. Field -- Chest compression technique: a neglected key to success in CPR / Charles F. Babbs -- Alternate CPR devices and techniques / Henry Halperin and Barr Rayburn -- Training adults to perform CPR : what works? / Barbara Riegel, Lars Wik, and Alidene Doherty -- External defibrillation / Gregory P. Walcott, Cheryl R. Killingsworth, and Raymond E. Ideker -- Public access defibrillation / Vincent N. Mosesso, Jr., Mary M. Newman, and Kristin R. Hanson -- Pacing during cardiac arrest / Allan S. Jaffe and Utpal H. Pandya -- Therapeutic hypothermia in the treatment of cardiac arrest / Benjamin S. Abella, Terry Vanden Hoek, and Lance B. Becker -- Percutaneous coronary bypass as an adjunct for resuscitation / Catherine Cooper and Bruce D. Spiess -- Principles of drug delivery during CPR / Edgar R. Gonzalez ... [et al.] -- Pharmacological resuscitation interventions / Wanchun Tang, Shijie Sun, and Max Harry Weil -- Use of vasopressor drugs / Anette C. Krismer ... [et al.] -- Buffer therapy / Martin von Planta -- Antiarrhythmic drugs and cardiac resuscitation / Brian Olshansky, Pamela Nerheim, and Richard Kerber -- Electrolyte disturbances and cardiopulmonary resuscitation / Domenic A. Sica -- Cardiac arrest in pregnancy / Alison A. Rodriguez and Gary A. Dildy, III -- Drowning / Jerome H. Modell and Andrea Gabrielli -- Cardiopulmonary resuscitation and early management of the lightning strike victim / Mary Ann Cooper and Sara Ashley Johnson -- Hypothermic cardiac arrest / Daniel F. Danzl -- Cardiopulmonary resuscitation in trauma / Rao R. Ivatury and Kevin R. Ward -- Monitoring techniques during resuscitation / Kevin R. Ward, R. Wayne Barbee, and Rao R. Ivatury -- Myocardial dysfunction postresuscitation / Alejandro Vasquez and Karl B. Kern -- Postresuscitation cerebral dysfunction : prevention and treatment / Antonio E. Mu-iz -- Pediatric cardiopulmonary resuscitation / Robert A. Berg and Vinay M. Nadkarni -- In-hospital resuscitation / Mary Ann Peberdy -- Successful systems for out-of-hospital resuscitation / Paul E. Pepe, Lynn A. Roppolo, and Leonard A. Cobb -- Animal models of resuscitation / Kevin R. Ward and R. Wayne Barbee -- Design of clinical trials related to medical emergencies / Alfred Hallstrom -- Ethics in resuscitation / Antonio E. Mu-iz -- The future of cardiopulmonary resuscitation : combination therapy / Joseph P. Ornato.
  • 2015 Springer
    David Goldsmith, Adrian Covic, Jonas Spaak, editors.
    This book provides a comprehensive overview of the clinical challenges faced during the treatment of patients with cardiorenal syndrome (CRS). The bidirectional link that associates renal and cardiovascular diseases means that patients with CRS have an increased risk of hospital admission and mortality as a result of their coexistence yet, there are no agreed guidelines for their management. Cardio-Renal Clinical Challenges takes clinical presentations and clinical problems as its base, and then discusses the evidence for best management of common clinical problems and the reasons for the complex interplay between the cardiac and renal systems. In addition, the link between heart failure and chronic kidney disease (CKD) can impose a considerable epidemiological burden thus this text also aims to address the issue of organizing healthcare to maximize both the opportunities for prevention and best healthcare economic returns. This book will be of immediate value and practical interest to all consulting and trainee cardiologists and renal physicians.
  • 2010 Springer
    Adel E. Berbari, Giuseppe Mancia (eds.).
    Chronic kidney disease with a worldwide prevalence of 10% in the general population is emerging as a major public health priority. Renal dysfunction is associated with a high risk for cardiovascular complications. The relationship between renal insufficiency and cardiovascular disease, termed the cardiorenal syndrome exists whether impairment of renal function is a consequence of primary renal parenchymal disease or primary heart disease. This book provides a comprehensive update analysis of our current understanding of the cardiorenal syndrome including epidemiology pathophysiologic mechanism.
  • 2010 Karger
    volume editors, Claudio Ronco, Rinaldo Bellomo, Peter A. McCullough.
    Pathophysiology of acute kidney injury -- Cardiorenal syndromes -- Organ crosstalk in multiple organ dysfunction syndromes -- Fluid assessment and management in the critically ill -- Practice of renal replacement therapy in the ICU -- Critical care nephrology issues -- Trials in acute kidney failure -- New horizons in critical care nephrology.
  • 2009 Springer
    Mogens L. Glass, Stephen C. Wood, editors.
    Overview of the respiratory system / S.C. Wood -- Control of respiration in aquatic vertebrates: Gas transport and gill function in water-breathing fish / S.F. Perry ... [et al.]. Patterns of acid-base regulation during exposure to hypercarbia in fishes / C.J. Brauner and D.W. Baker. Buoyancy control in aquatic vertebrates / B. Pelster. Gas exchange and control of respiration in air-breathing teleost fish / M.L. Glass and F.T. Rantin. Effects of temperature on cardiac function in teleost fish / A.L. Kalinin ... [et al.]. Physiological evidence indicates lungfish as a sister group to the land vertebrates / M.L. Glass. Aestivation in amphibians, reptiles, and lungfish / M.L. Glass, J. Amin-Naves, and G.S.F. da Silva -- Evolution of pulmonary mechaincs and respiratory control: Trade-offs in the evolution of the respiratory apparatus of chordates / S.F. Perry, W. Klein, and J.R. Codd. Environmental selection pressures shaping the pulmonary surfactant system of adult and developing lungs / S. Orgeig and C.B. Daniels. Midbrain structures and control of ventilation in amphibians / L.H. Gargaglioni and L.G.S. Branco. Comparative aspects of hypoxia tolerance of the ectothermic vertebrate heart / H. Gesser and J. Overgaard. Control of the heart and of cardiorespiratory interactions in ectothermic vertebrates / E.W. Taylor and T. Wang. The endocrine-paracrine control of the cardiovascular system / B. Tota and M.C. Cerra. Stoking the brightest fires of life among vertebrates / Raul K. Suarez and Kenneth C. Welch -- Respiratory physiology of birds : metabolic control: Prenatal development of cardiovascular regulation in avian species / J. Altimiras, D.A. Crossley II, and E. Villamor. Control of breathing in birds : implications for high-altitude flight / G.R. Scott and W.K. Milsom -- Mammalian and human physiology: Peripheral chemoreceptors in mammals : structure, function and transduction / P. Kumar. Central chemosensitivity in mammals / L.K. Hartzler and R.W. Putnam. Human exercise physiology / S. Volianitis and Niels H. Secher.
  • 2007 ClinicalKey
    [edited by] David Sidebotham, Andrew Mckee, Michael Gillham and Jerrold H. Levy
    This new bedside manual guides you through all the practical aspects of managing patients following cardiothoracic surgery and critically ill cardiology patients. Primarily designed to use in cardiothoracic intensive care units and coronary care units, it covers the perioperative management for the full range of cardiothoracic surgical procedures, the management of complications, and related issues. Core topics in cardiothoracic critical care, such as hemodynamic instability, arrhythmias, bleeding, and mechanical cardiac support, are afforded broad coverage. Also included are sections on advanced ventilatory techniques and veno-venous ECMO for treating severe respiratory failure, as well as nutritional support, treating and preventing infection, renal failure, and care of the dying patient. Concisely written and featuring liberal use of illustrations as well as an integrated, tightly edited style, and a limited number of key references, this volume will become your reference of choice for the care of of cardiothoracic surgery patients and critically ill cardiology patients. Also included is a companion CD-ROM featuring over 700 still and 200 video clips of radiographs, CT scans, MRI scans, and echocardiograms, both transthoracic and transesophageal. Find information quickly with concisely written text. Get a more complete picture with extensive illustrations. Focus on just the information you need using a a limited number of key references. Navigate the complexities of critical care for a fulll range of cardiothoracic surgery patients with in-depth coverage of perioperative care, management of complications, and more. Enhance your knowledge through a companion CD-ROM featuring the latest in cardiothoracic imaging techniques.
  • 2011 Springer
    Mark R. Katlic, editor.
    Part 1. General Aspects of Care -- Invited Commentary / Ronnie A. Rosenthal -- The Epidemiology and Economics of Cardiothoracic Surgery in the Elderly / David A. Etzioni and Vaughn A. Starnes -- Principles of Geriatric Surgery / Mark R. Katlic -- Geriatric Models of Care / Elizabeth A. Capezuti, Patricia Ursomanno, Marie Boltz and Hongsoo Kim -- Delirium After Cardiac Surgery / James L. Rudolph -- Cardiac Rehabilitation in the Elderly / Carl I. Gonzales and Lois A. Killewich -- Legal Aspects of Geriatric Surgery / Marshall B. Kapp -- Ethical Issues in Cardiothoracic Surgery for the Elderly / Susan M. Hecker and Robert M. Sade -- Acute Pain Control in Geriatric Patients After Cardiac and Thoracic Surgeries / Jack M. Berger, Tawfik Ayoub and Jayeshkumar Patel -- Palliative Care in the Elderly / Geoffrey P. Dunn -- Cardiopulmonary Trauma in the Elderly / Jay Menaker and Thomas M. Scalea -- Imaging Features of the Normal Aging Chest / Carol C. Wu and Jo-Anne O. Shepard -- Cardiac Imaging in the Elderly / Faisal Nabi, Dipan J. Shah, Stephen H. Little and Su Min Chang -- Part 2. Physiologic Changes -- Invited Commentary / Michael E. Zenilman -- Biology of Aging / Huber R. Warner -- Hematologic Disorders in the Elderly / Ilene C. Weitz -- Anticoagulation in the Older Surgical Patient / M. Kate Elfrey and Susan J. Zieman -- Medication Usage in Older Cardiothoracic Surgical Patients / Richard A. Marottoli, Sean M. Jeffery and Roshini C. Pinto-Powell -- Wound Healing in the Elderly / Christopher G. Engeland and Praveen K. Gajendrareddy -- Pulmonary Changes in the Elderly / Keenan A. Hawkins and Ravi Kalhan -- Cardiac Changes in the Elderly / Wilbert S. Aronow and William H. Frishman -- Renal Changes in the Elderly / Carlos G. Musso and Dimitrios G. Oreopoulos -- Gastrointestinal and Liver Changes in the Elderly / Vadim Sherman, John A. Primomo and F. Charles Brunicardi -- Neurologic and Cognitive Changes in the Elderly / J. Riley McCarten -- Hormonal Changes During and After Cardiac Surgery / Marcello Maggio, Chiara Cattabiani and Gian Paolo Ceda -- Part 3. Cardiac Surgery -- Invited Commentary / William A. Baumgartner -- Preoperative Evaluation and Preparation in the Elderly Cardiac Surgery Patient / Joseph C. Cleveland -- Cardiac Anesthesia in the Elderly / Eric W. Nelson and James H. Abernathy -- Postoperative and Critical Care in the Elderly Cardiac Surgery Patient / Christopher J. Barreiro, Kerry J. Stewart and Glenn Whitman -- Surgery for Ischemic Coronary Disease in the Elderly / Margarita T. Camacho and Melissa L. Wong -- Surgical Treatment of Aortic Valve Disease in the Elderly / Vinod H. Thourani and Robert A. Guyton -- Surgical Treatment of Mitral Valve Disease in the Elderly / Maqsood M. Elahi and Kenton J. Zehr -- Surgical Treatment of Thoracic Aortic Disease in the Elderly / Arnar Geirsson -- Surgical Treatment of Pericardial Disease in the Elderly / Joshua Kindelan and Alberto de Hoyos -- Pacemakers and Implantable Cardioverter Defibrillators in the Elderly / Luciana Armaganijan and Jeff S. Healey -- Heart Transplantation and Mechanical Assistance in the Elderly / Edwin C. McGee -- Part 4. Thoracic Surgery -- Invited Commentary / Joseph LoCicero -- Preoperative Evaluation and Preparation in the Elderly Thoracic Surgery Patient / Ticiana Leal, Noelle K. LoConte, Anai Kothari and Tracey L. Weigel -- Thoracic Anesthesia in the Elderly / Anne C. Kolker -- Postoperative and Critical Care in the Elderly Thoracic Surgery Patient / Brannon R. Hyde and Joseph B. Zwischenberger -- Adjuvant Therapy for Lung Cancer in the Elderly / Jared Weiss and Corey J. Langer -- Pulmonary Surgery for Malignant Disease in the Elderly / Sarah E. Billmeier and Michael T. Jaklitsch -- Benign Thoracic Disease in the Elderly / Rita A. Mukhtar and Pierre R. Theodore -- Lung Transplantation in the Elderly / Juan J. Fibla, Sandra C. Tomaszek and Stephen D. Cassivi -- Esophageal Surgery for Malignant Disease in the Elderly / Philip A. Rascoe and John C. Kucharczuk -- Esophageal Surgery for Benign Disease in the Elderly / Rose E. Hardin, Katie S. Nason and James D. Luketich -- Surgery for Mediastinal Disease in the Elderly / Cameron D. Wright -- Surgery for Pleural Disease in the Elderly / Raja M. Flores and Naveed Z. Alam -- Surgery for Chest Wall Disease in the Elderly / Daniel L. Miller -- Surgery of the Trachea and Bronchi in the Elderly / Douglas J. Mathisen and Ashok Muniappan.
  • 2014 Springer
    Brendon J. Coventry, editor.
    Written by "internationally acclaimed" specialists, Cardio-Thoracic, Vascular, Renal and Transplant Surgery provides pertinent and concise procedure descriptions spanning benign and malignant problems and minimally invasive procedures. Complications are reviewed when appropriate for the organ system and problem, creating a book that is both comprehensive and accessible. Stages of operative approaches with relevant technical considerations are outlined in an easily understandable manner. Forming part of the series, Surgery: Complications, Risks and Consequences, this volume Cardio-Thoracic, Vascular, Renal and Transplant Surgery provides a valuable resource for all general surgeons and residents in training. Other healthcare providers will also find this a useful resource.
  • 2006 Springer
    edited by David A. Morrow ; foreword by Elliot Antman.
    Biomarkers of myocardial necrosis: past, present, and future / Robert H. Christenson and Hassan M.E. Azzazy -- Analytical issues for the clinical use of cardiac troponin / Alan H.B. Wu -- Defining myocardial infarction / Allan S. Jaffe and Luciano Babuin -- Biomarkers in the emergency department: rapid diagnosis and triage / Jin H. Han and W. Brian Gibler -- Cardiac troponin for risk assessment and management of non-ST-elevation acute coronary syndrome / Bertil Lindahl -- Biomarkers of necrosis for risk assessment and management of ST-elevation myocardial infarction / Evangelos Giannitsis and Hugo A. Katus -- Cardiac troponin after revascularization procedures / Warren J. Cantor and L. Kristin Newby -- Biomarkers of necrosis in heart failure: past, present, and future directions / Emil Missov, James Rider, and Leslie Miller -- Is there a role for cardiac troponin and other biomarkers in patients with pulmonary embolism? / Samuel Z. Goldhaber -- Cardiac troponin in conditions other than acute coronary syndromes / Fred S. Apple and David A. Morrow -- Degradation of cardiac troponins: implications for clinical practice / Allan S. Jaffe and Jennifer E. Van Eyk -- Clinical use of natriuretic peptides for the diagnosis and management of heart failure / Alan Maisel -- Natriuretic peptides in acute and chronic coronary artery disease / Shuaib M. Abdullah and James A. de Lemos -- Novel markers of hemodynamic stress / Ellen O. Weinberg and Richard T. Lee -- Clinical and research applications of markers of thrombosis / Manesh R. Patel and Richard C. Becker -- Measures of platelet activation and aggregation / Jean-Philippe Collet and Gilles Montalescot -- Monocyte-platelet aggregates in patients with ischemic heart disease / Matthew D. Linden and Mark I. Furman -- Measurement of atherogenic lipoproteins in cardiovascular risk assessment / Richard L. Dunbar and Daniel J. Rader -- Lipoprotein-associated phospholipase A2 and other lipid-related biomarkers in cardiovascular disease / Natalie Khuseyinova and Wolfgang Koenig -- A multimarker approach to evaluation of patients with acute coronary syndrome / David A. Morrow -- Cardiac biomarkers by point-of-care testing / Paul O. Collinson -- Proteomics and cardiovascular biomarker discovery / Emerson Liu and Robert E. Gerszten -- Genetic markers in cardiovascular disease / Marc S. Sabatine. Developing a marker of ischemia: clinical and research challenges / Robert L. Jesse -- Emerging biomarkers of myocardial ischemia / Jesse E. Adams -- Inflammation in cardiovascular disease: the biological basis of inflammatory biomarkers / Peter Libby -- Analytical issues for the clinical use of c-reactive protein / Nader Rifai -- C-reactive protein as a tool for risk assessment in primary prevention / Shari S. Bassuk and Paul M. Ridker -- High-sensitivity c-reactive protein for risk assessment in acute coronary syndromes / Luigi M. Biasucci and Antonio Abbate -- Beyond c-reactive protein: novel markers of vascular inflammation / Christopher Heeschen -- Biomarkers of inflammation: implications in patients with heart failure / Biykem Bozkurt -- Biomarkers of infection and risk of coronary heart disease / Joseph B. Muhlestein -- Biology of the natriuretic peptides / Charlotte Kragelund and Torbjørn Omland -- Analytical issues for the clinical use of b-type natriuretic peptide and n-terminal pro b-type natriuretic peptide / Johannes Mair --
    Also available: Print – 2006
  • 2013 Wiley
    edited by Marcus Flather, Deepak L. Bhatt, Tobias Geisler.
    Reporting results of clinical trials for publication / Marcus Flather and Tobias Geisler -- The management of chronic coronary artery disease / Sabu Thomas and William E. Boden -- Acute coronary syndromes (ST elevation and non-ST-elevation) / Tobias Geisler, Deepak L. Bhatt, and Marcus Flather -- Heart failure / Chris O'Connor and Wendy G. Strough -- Atrial fibrillation / Chee W. Khoo and Gregory Y.H. Lip -- Electrophysiology and pacing / Sabine Ernst and Irina Horduna -- Percutaneous coronary intervention / Dharam J. Kumbhani and Deepak L. Bhatt -- Randomized controlled trials in cardiac surgery-is there any alternative? / Thanos Athanasiou, Amir Sepehripour, and John Pepper -- Adult congenital heart disease / Cary C. Ward, J. Kevin Harrison, and Tom Bashore -- Cardiac imaging / Aiden Abidov and Daniel S. Berman -- Prevention of cardiovascular disease / Alice J. Owen and Christopher M. Reid.
  • 2013 Springer
    Carlo Catalano, Michele Anzidei, Alessandro Napoli (editors).
    The availability and diffusion of high-performance technologies has strengthened the role of CT angiography and MR angiography as simple, reliable techniques for the characterization and treatment planning of the principal diseases of the cardiovascular system, an understanding of which has become essential for all radiologists. The aim of this book is to provide concise but thorough information and guidance on the main methods and examination techniques used when performing high-quality CT angiography and MR angiography studies in a broad range of clinical settings. The lucid text is supported by a large number of case studies and is rich in advice on image interpretation and practical suggestions for the evaluation and reporting of the examinations. Importantly, a central feature is detailed comparison of the advantages and limitations of the two techniques in various diseases and vascular regions; the book will therefore enable both trainee and expert radiologists to understand their indications and to select the most appropriate technique in different contexts.
  • 2012 Springer Protocols
    edited by Xu Peng, Marc Antonyak.
    Use of whole embryo culture for studying heart development / Calvin T. Hang and Ching-Pin Chang -- Quantifying cardiac functions in embryonic and adult zebrafish / Tiffany Hoage, Yonghe Ding, and Xiaolei Xu -- Analysis of the patterning of cardiac outflow tract and great arteries with angiography and vascular casting / Ching-Pin Chang -- Morpholino injection in Xenopus / Panna Tandon [and others] -- Chicken chorioallantoic membrane angiogenesis model / Domenico Ribatti -- Visualizing vascular networks in zebrafish : an introduction to microangiography / Christopher E. Schmitt, Melinda B. Holland, and Suk-Won Jin -- Whole-mount confocal microscopy for vascular branching morphogenesis / Yoh-suke Mukouyama [and others] -- Visualization of mouse embryo angiogenesis by fluorescence-based staining / Yang Liu, Marc Antonyak, and Xu Peng -- Miniaturized assays of angiogenesis in vitro / May J. Reed and Robert B. Vernon -- Analysis of the endocardial-to-mesenchymal transformation of heart valve development by collagen gel culture assay / Yiqin Xiong, Bin Zhou, and Ching-Pin Chang -- Quantification of myocyte chemotaxis : a role for FAK in regulating directional motility / Britni Zajac [and others] -- Analysis of neural crest cell fate during cardiovascular development using Cre-activated lacZ/[beta]-galactosidase staining / Yanping Zhang and L. Bruno Ruest -- Indirect immunostaining on mouse embryonic heart for the detection of proliferated cardiomyocyte / Jieli Li, Marc Antonyak, and Xu Peng -- Isolation and characterization of vascular endothelial cells from murine heart and lung / Yixin Jin [and others] -- Isolation and characterization of embryonic and adult epicardium and epicardium-derived cells / Bin Zhou and William T. Pu -- Vascular smooth muscle cells : isolation, culture, and characterization / Richard P. Metz, Jan L. Patterson, and Emily Wilson -- C-kit expression identifies cardiac precursor cells in neonatal mice / Michael Craven, Michael I. Kotlikoff, and Alyson S. Nadworny -- Cardiomyocyte apoptosis in heart development : methods and protocols / Dongfei Qi and Mingui Fu -- Adenovirus-mediated gene transfection in the isolated lymphatic vessels / Anatoliy A. Gashev [and others] -- Isolation of cardiac myocytes and fibroblasts from neonatal rat pups / Honey B. Golden [and others] -- The application of genome-wide RNAi screens in exploring varieties of signaling transduction pathways / Shenyuan Zhang and Hongying Zheng -- Application of atomic force microscopy measurements on cardiovascular cells / Xin Wu [and others] -- In utero assessment of cardiovascular function in the embryonic mouse heart using high-resolution ultrasound biomicroscopy / Honey B. Golden [and others] -- Isolation and preparation of RNA from rat blood and lymphatic microvessels for use in microarray analysis / Eric A. Bridenbaugh -- Visual data mining of coexpression data to set research priorities in cardiac development research / Vincent VanBuren -- High-speed confocal imaging of zebrafish heart development / Jay R. Hove and Michael P. Craig -- Measurement of electrical conduction properties of intact embryonic murine hearts by extracellular microelectrode arrays / David G. Taylor and Anupama Natarajan.
  • 2008 Karger
    volume editors, Enrique Z. Fisman, Alexander Tenenbaum.
    Hyperglycemia and the pathobiology of diabetic complications / Aronson, D. -- Endothelial dysfunction in normal and abnormal glucose metabolism / Esper, R.J. ... [et al.] -- Biomarkers in cardiovascular diabetology: interleukins and matrixins / Fisman, E.Z. ; Adler, Y.; Tenenbaum, A. -- Arterial elasticity in cardiovascular disease: focus on hypertension, metabolic syndrome and diabetes / Cernes, R.; Zimlichman, R.; Shargorodsky, M. -- Hypertension and diabetes / Grossman, E.; Messerli, F.H. -- Impaired glucose metabolism and cerebrovascular diseases / Tanne, D. -- Impact of metabolic syndrome in patients with acute coronary syndrome / Feinberg, M.S.; Schwartz, R.; Behar, S. -- Optimal management of combined dyslipidemia: what have we behind statins monotherapy? / Tenenbaum, A. ... [et al.] -- Non-insulin antidiabetic therapy in cardiac patients: current problems and future prospects / Fisman, E.Z.; Motro, M.; Tenenbaum, A.
  • NLM
    Also available: Print – 1983
  • v. 1-2, 2006. Springer Protocols
    v. 2, 2006 Springer Protocols
    edited by Qing K. Wang.
    v. 1. Genetics -- v. 2. Molecular medicine.
  • v. 1, 1974.
    Senta S. Rogers and Irvin C. Mohler.
    Status: Not Checked OutLane Catalog Record
    v. 1. 1960-1973.
  • 2005 Springer
    Giuseppe Barbaro, Franck Boccara (eds.) ; foreword by W. Rozenbaum.
  • 2009 Springer
    Giuseppe Barbaro, Franck Boccara, (eds.) ; in cooperation with Giorgio Barbarini.
  • 2009 Springer
    edited by Keith C. Ferdinand and Annemarie Armani.
    Cardiovascular disease in racial/ethnic minorities: overview and perspectives -- Epidemiology of cardiovascular diseases and risk factors among racial/ethnic populations -- Unmasking racial/ethnic disparities in cardiovascular disease: nutritional, socioeconomic, cultural, and health-care-related contributions -- Race and genetics -- Race, genetics and cardiovascular disease -- Hypertension and stroke in racial/ethnic groups -- Dyslipidemia in racial/ethnic groups -- Novel & emerging risk factors in racial/ethnic groups -- Weight loss interventions to control blood pressure in an increasingly overweight, multi-ethnic society -- Obesity and the cardiometabolic syndrome: impact on chronic kidney disease and CVD -- Risk calculation and clustering within racial/ethnic groups -- Cardiovascular imaging in racial/ethinc populations: implications for the adequate application of cardiovascular imaging techniques guided by racial/ethnical risk factor variations -- Unique aspects of vascular and cardiac ultrasound in racial/ethnical groups -- Heart failure in racial/ethnic group -- Minority women and cardiovascular disease.
  • 2005 Springer
    edited by Gary Gerstenblith.
    Aging of the heart and arteries : relevance to cardiovascular disease / Samer S. Najjar and Edward G. Lakatta -- Frailty : keystone in the bridge between geriatrics and cardiology / William Russell Hazzard -- Cardiovascular risk factors in the elderly : evaluation and intervention / Susan J. Zieman and Beth R. Malasky -- Stable coronary artery disease in the elderly / Beth R. Malasky and Joseph S. Alpert -- Age and mortality and morbidity in ST-segment elevation myocardial infarction / Steven P. Schulman and Gary Gerstenblith -- Unstable angina/non-ST-elevation myocardial infarction in the elderly / Stephen D. Wiviott and Christopher P. Cannon -- Percutaneous coronary intervention in the elderly / Michael J. McWilliams and Eric J. Topol -- Cardiac surgery in the elderly / David D. Yuh and William A. Baumgartner -- Heart failure in the elderly / Michael W. Rich -- Valvular heart disease in the elderly / Milind Y. Desai and Gary Gerstenblith -- Arrhythmia management in the elderly / Jonathan P. Piccini and Hugh Calkins -- Peripheral arterial disease in the elderly / Emile R. Mohler III and William R. Hiatt -- Cardiac rehabilitation in older cardiac patients / Philip A. Ades -- Clinical pharmacology / Janice B. Schwartz -- Medical treatment of the cardiac patient approaching the end of life / Lofty L. Basta, W. Daniel Doty, and Michael D.D. Geldart.
  • 2013 CRCnetBASE
    edited by Nilanjana Maulik.
    Pt. 1. Epidemiological study of heart disease -- pt. 2. Epigenetic modifications in arterial and heart diseases -- pt. 3. Cardiovascular disease -- pt. 4. Nutritional and other therapeutic interventions for CVD.
  • 2005 Karger
    volume editors, Claudio Ronco, Alessandra Brendolan, Nathan W. Levin.
    Hemodialysis, from early days to tomorrow / Ritz, E. ... [et al.] -- Mechanisms of solute transport in extracorporeal therapies / Ronco, C., Levin, N.W. -- Machines for hemodialysis / Polaschegg, H.-D. -- Mathematical model to characterize internal filtration / Fiore, G.B., Ronco, C. -- Extracorporeal sensing techniques / Schneditz, D. -- Water treatment for hemodialysis / Cappelli, G. ... [et al.] -- Online convective therapies / Santoro, A. ... [et al.] -- Selected lessons learned from the dialysis outcomes and practice patterns study (DOPPS) / Pisoni, R.L., Greenwood, R.N. -- What did we learn from the hemo study? / Greene, T. -- What are we expecting to learn from the MPO study? / Locatelli, F., Pozzoni, P., Di Filippo, S. -- A new initiative in nephrology: 'kidney disease: improving global outcomes / Lameire, N. ... [et al.] -- Is there a magic in long nocturnal dialysis? / Charra, B. -- Mid-dilution: the perfect balance between convection and diffusion / Santoro, A.; Gaggi, R. ... [et al.] -- Sequential hemofiltration-hemodiafiltration technique / Amato, M. ... [et al.] -- Should nephrologists be in charge? / Konner, K. -- Challenges in interventional nephrology / Riella, M.C. -- Vascular access education, planning and percutaneous interventions by nephrologists / Asif, A., Merrill, D., Pennell, P. -- Whole body, single frequency bioimpedance / Piccoli, A. -- Use of segmental multifrequency bioimpedance spectroscopy in hemodialysis / Levin, N.W. ... [et al.] -- Cardiovascular risk in patients with end-stage renal disease / Wang, Y. ... [et al.] -- Improving removal of protein-bound retention solutes / Bammens, B., Evenepoel, P. -- Inflammation in end-stage renal disease / Stenvinkel, P. -- Interaction between nutrition and inflammation in hemodialysis patients / Kuhlmann, M.K., Levin, N.W. -- Monocytes from dialysis patients exhibit characteristics of senescent cells / Carracedo, J. ... [et al.] -- Modifiable risk factors for cardiovascular disease in CKD patients / Seibert, E., Kuhlmann, M.K., Levin, N.W. -- The cardiovascular burden of the dialysis patient / Bowry, S.K., Kuchinke-Kiehn, U., Ronco, C. -- Oxidative stress and reactive oxygen species / Galli, F. ... [et al.] -- Calcium, phosphorus and vitamin D disorders in uremia / Slatopolsky, E., Brown, A., Dusso, A. -- Cardiovascular calcification in end stage renal disease / Raggi, P. -- The mechanism of calcium deposition in soft tissues / Brancaccio, D., Cozzolino, M. -- Biosimilars, generic versions of the first generation of therapeutic proteins / Crommelin, D. ... [et al.] -- Electrophysiological response to dialysis / Santoro, A. ... [et al.] -- Noninvasive assessment of vascular function / Schneditz, D., Kenner, T. -- New insights in uremic toxicity / Vanholder, R., Glorieux, G. -- Continuous renal replacement therapy for end-stage renal disease / Gura, V. ... [et al.] -- Slow continuous intravenous plasmapheresis (sciptm) / Handley, H.H. ... [et al.] -- Membraneless dialysis-is it possible? / Leonard, E.F., Cortell, S., Vitale, N.G.
    Also available: Print – 2005
  • 1978-
    [series editor, Graeme S. Avery].
    Status: Not Checked OutLane Catalog Record
    v.1, Antiarrhythmic, antihypertensive, and lipid lowering drugs ; v.2, [beta]-adrenoceptor blocking drugs ; v.3, Antithrombotic drugs ; v.4, Antihypertensive drugs today.
  • 2008 Springer
    Ramon Ribes, Sergio Mejia.
  • v. 1-2, 1972
    edited by D. H. Bergel.
    Status: Not Checked OutLane Catalog Record
  • 2006 Karger
    volume editor, Stefan Dhein.
    Cardiac connexins: genes to nexus / Duffy, H.S., Fort, A.G., Spray, D.C. -- Physiology of cardiovascular gap junctions / Van Veen, T.A.B., Van Rijen, H.V.M., Jongsma, H.J. -- Role of connexin43-interacting proteins at gap junctions / Giepmans, B.N.G. -- Life cycle of connexins: regulation of connexin synthesis and degradation / Salameh, A. -- Gap junctions and propagation of the cardiac action potential / Bernstein, S.A., Morley, G.E. -- Micropatterns of propagation / Lee, P., Pogwizd, S.M. -- Pharmacology of cardiovascular gap junctions / Hervé, J.-C., Dhein, S. -- Structural and functional coupling of cardiac myocytes and fibroblasts / Camelliti, P., Green, C.R., Kohl, P. -- Connexins and cardiac arrhythmias / Van Rijen, H.V.M. ... [et al.] -- Role of connexins in atrial fibrillation / Dhein, S. -- Connexins in the sinoatrial and atrioventricular nodes / Boyett, M.R. ... [et al.] -- Cardiac ischemia and uncoupling: gap junctions in ischemia and infarction / Dhein, S. -- Connexin 43 and ischemic preconditioning / Schulz, R., Heusch, G. -- Alterations in cardiac connexin expression in cardiomyopathies / Severs, N.J. ... [et al.] -- Alterations of connexin 43 in the diabetic rat heart / Lin, H. ... [et al.] -- Connexins in atherosclerosis / Chadjichristos, C.E., Derouette, J.-P., Kwak, B.R. -- Connexin-dependent communication within the vascular wall: contribution to the control of arteriolar diameter / De Wit, C., Wölfle, S.E., Höpfl, B. -- Cx40 polymorphism in human atrial fibrillation / Hauer, R.N.W. ... [et al.].
  • 2005 Springer
    edited by Mohan K. Raizada, Julian F.R. Paton, Sergey Kasparov, Michael J. Katovich.
    Angiotensin II receptor polymorphisms and hypertension / Bruno Baudin -- Angiotensinogen gene polymorphisms and hypertension / Ashok Kumar -- Substitution mapping: using congenic strains to detect genes controlling blood pressure / Bina Joe and Michael R. Garrett -- Local production of angiotensinogen: insights from genetic manipulation of mice / Kamal Rahmouni and Curt D. Sigmund -- Cardiovascular pharmacogenomics / Julie A. Johnson and Larisa H. Cavallari -- Genetic polymorphisms and responses to HMG-CoA, reductase inhibitors / Anke-Hilse Maitland-van der Zee, Olaf H. Klungel, and Anthonius de Boer -- Monogenic causes of heart failure: familial dilated cardiomyopathy / Hideko Kasahara -- Gene therapy vs. pharmacotherapy / Ryuichi Morishita -- Molecular therapeutic approaches for myocardial protection / Alok S. Pachori, Luis G. Melo, and Victor J. Dzau -- Gene transfer and the cardiovascular system / William H. Miller ... [et al.] -- Kallikrein gene transfer in hypertension, cardiovascular and renal disease, and stroke / Julie Chao and Lee Chao -- Current and future novel targets of gene therapy for hypertension / Michael J. Katovich, Justin L. Grobe, and Mohan K. Raizada -- Application of viral gene transfer in studies of neurogenic hypertension / Sergey Kasparov, A.G. Teschemacher, and Julian F.R. Paton -- Vigilant vectors: intelligent gene vectors for cardioprotection in myocardial ischemia / M. Ian Phillips and Yi Tang -- Gene therapy for cerebral arterial diseases / Yoshimasa Watanabe and Donald D. Heistad -- Therapeutic angiogenesis and vasculogenesis for tissue regeneration / Paolo Madeddu -- Cell transplantation: the new frontier / Shafie Fazel ... [et al.] -- Embryonic stem cells and the cardiovascular system / Neta Lavon and Nissim Benvenisty.
  • 2013 Springer
    Saif Anwaruddin [and others], editors.
    A basic understanding of cardiovascular physiology is essential for optimal patient care. This practical book provides a concise tutorial of all the essential aspects of cardiovascular hemodynamics and the techniques used to assess cardiovascular performance. A high-yield reference, this book is replete with figures, tracings, tables, and clinical pearls that reinforce the basic tenets of hemodynamics. From identifying key findings of the patient history and physical exam to correlating hemodynamic tracings with acute clinical presentations, this book arms the reader with the tools necessary to handle any hemodynamic-related situation.
  • 2011 ClinicalKey
    [edited by] Vincent B. Ho, Gautham P. Reddy.
    Embryologic Basis and Segmental Approach to Imaging of Congenital Heart Disease -- Cardiac Anatomy -- Coronary Anatomy -- Physiology of the Heart -- Radiology of the Heart : Plain Film Imaging and Diagnosis -- Echocardiography -- Diagnostic Coronary Angiography -- Physics of Cardiac Computed Tomography -- Clinical Techniques of Cardiac Computed Tomography -- Radiation Dose Reduction Strategies in Cardiac Computed Tomography -- Contrast Agents and Medications in Cardiac Computed Tomography -- Image Postprocessing in Cardiac Computed Tomography -- Methods for Cardiac Magnetic Resonance Imaging -- Clinical Techniques of Cardiac Magnetic Resonance Imaging : Morphology, Perfusion, and Viability -- Clinical Techniques of Cardiac Magnetic Resonance Imaging : Function -- Clinical Techniques of Cardiac Magnetic Resonance Imaging : Functional Interpretation and Image Processing -- Magnetic Resonance Evaluation of Blood Flow -- Contrast Agents in Magnetic Resonance Imaging -- Magnetic Resonance Imaging Safety -- Physics and Instrumentation of Cardiac Single Photon Emission Computed Tomography -- Clinical Single Photon Emission Computed Tomography Cardiac Protocols -- Radiopharmaceutical Single Photon Emission Computed Tomography Imaging Agents -- Physics and Instrumentation of Cardiac Positron Emission Tomography/Computed Tomography -- Clinical Techniques of Positron Emission Tomography and PET/CT -- Radiopharmaceuticals and Radiation Dose Considerations in Cardiac Positron Emission Tomography and PET/CT -- Pharmacologic Stress Agents -- Congenital Percutaneous Interventions -- Congenital Cardiac Surgery -- Percutaneous Catheter-Based Treatment of Coronary and Valvular Heart Disease -- Surgery for Acquired Cardiac Disease -- Imaging of Atrial Fibrillation Intervention -- Coronary Calcium Assessment -- Congenital Coronary Anomalies -- Indications and Patient Selection in Obstructive Coronary Disease -- Interpretation and Reporting in Obstructive Coronary Disease -- Coronary Artery Aneurysms -- Imaging of Coronary Revascularization : Coronary Stents and Bypass Grafts -- Imaging of Coronary Revascularization : Coronary Stents and Bypass Grafts -- Coarctation of the Aorta -- Vascular Rings and Slings -- Magnetic Resonance Imaging of the Aorta and Left Ventricular Function in Inherited and Congenital Aortic Disease -- Atrial Septal Defect -- Ventricular Septal Defect -- Patent Ductus Arteriosus -- Transposition of the Great Arteries -- Truncus Arteriosus -- Anomalous Pulmonary Venous Connections and Drainage -- Tetralogy of Fallot -- Ebstein Anomaly -- Complex Congenital Heart Disease -- Magnetic Resonance Imaging in the Postoperative Evaluation of the Patient with Congenital Heart Disease -- Atherosclerotic Coronary Artery Disease -- Acute Coronary Syndrome -- Magnetic Resonance and Computed Tomographic Imaging of Myocardial Perfusion -- Nuclear Medicine Imaging of Myocardial Perfusion -- Magnetic Resonance and Computed Tomographic Imaging of Myocardial Function -- Nuclear Medicine Imaging of Ventricular Function -- Magnetic Resonance Imaging of Myocardial Viability -- Nuclear Medicine Imaging of Myocardial Viability -- Postoperative Imaging of Ischemic Cardiac Disease -- Aortic and Mitral Valvular Disease -- Tricuspid and Pulmonary Valvular Disease -- Dilated Cardiomyopathy -- Restrictive Cardiomyopathy -- Hypertrophic Cardiomyopathy -- Arrhythmogenic Right Ventricular Dysplasia -- Myocarditis -- Cardiac Tumors -- Pericardial Effusion -- Acute Pericarditis -- Constrictive Pericarditis -- Arterial Anatomy of the Thorax -- Arterial Anatomy of the Abdomen -- Arterial Anatomy of the Pelvis and Lower Extremities -- Arterial Anatomy of the Upper Extremities -- Venous Anatomy of the Thorax -- Venous Anatomy of the Abdomen and Pelvis -- Venous Anatomy of the Extremities -- Vascular Ultrasonography : Physics, Instrumentation, and Clinical Techniques -- Physics of Computed Tomography -- Computed Tomographic Angiography : Clinical Techniques -- Magnetic Resonance Angiography : Physics and Instrumentation -- Magnetic Resonance Angiography : Clinical Techniques -- Basic Three-Dimensional Postprocessing in Computed Tomographic and Magnetic Resonance Angiography -- Advanced Three-Dimensional Postprocessing in Computed Tomographic and Magnetic Resonance Angiography -- Nuclear Medicine : Extrathoracic Vascular Imaging -- Percutaneous Vascular Interventions -- Vascular Surgery -- Noninvasive Imaging of Atherosclerosis -- Carotid Artery Disease -- Ultrasound Evaluation of the Carotid Arteries -- Magnetic Resonance and Computed Tomographic Angiography of the Extracranial Carotid Arteries -- Thoracic Aortic Aneurysms -- Acute Aortic Syndrome -- Thoracic Aortic Trauma -- Thoracic Aortitis -- Subclavian Steal Syndrome -- Acute Pulmonary Thromboembolic Disease -- Chronic Pulmonary Embolism -- Pulmonary Hypertension -- Pulmonary Edema -- Pulmonary Hemorrhage and Vasculitis -- The Abdominal Aorta -- Postendograft Imaging of the Abdominal Aorta and Iliac Arteries -- Open Repair of Abdominal Aortic Aneurysms and Postoperative Assessment -- Magnetic Resonance Imaging of Vascular Disorders of the Abdomen -- Renal Artery Hypertension -- Renal Arteries : Computed Tomographic and Magnetic Resonance Angiography -- Renal Artery Scintigraphy -- Sonography of the Renal Vessels -- Inferior Vena Cava and Its Main Tributaries -- Vascular Imaging of Hepatic Transplantation -- Vascular Imaging of Renal and Pancreatic Transplantation -- Peripheral Artery Disease -- Lower Extremity Operations and Interventions -- Computed Tomographic Angiography of the Lower Extremities -- Peripheral Magnetic Resonance Angiography -- Vascular Diseases of the Upper Extremities -- Venous Sonography of the Upper Extremities and Thoracic Outlet -- Hemodialysis Fistulas.
  • 2015 Springer
    Elena Aikawa, editor.
    Part 1: Preclinical imaging of mechanisms of atherosclerosis and its complications -- Pathobiology and basic mechanisms of atherosclerosis -- Ultrasound imaging of endothelial cell activation and damage in atherosclerosis -- Molecular imaging of macrophages -- Optical molecular imaging of inflammation and calcification in atherosclerosis -- Imaging of antigen-presenting cells -- Imaging of oxidation-specific epitopes -- Intravascular molecular imaging -- Imaging of complications of atherosclerosis (platelets aggregation and thrombosis) -- Part 2: Imaging insights into mechanisms of calcific aortic valve disease (CAVD) and calcification -- Pathobiology and basic mechanisms of CAVD -- Molecular imaging of aortic valve inflammation and calcification: Preclinical studies -- PET CT imaging of inflammation and calcification in CAVD: Clinical studies -- Ultrasound imaging of CAVD -- Micro-OCT imaging of microcalcification -- Part 3: Clinical imaging of inflammation and calcification -- MR imaging in cardiovascular disease -- Molecular mechanisms of atherosclerosis imaged by MR -- Cardiovascular nuclear imaging -- Preclinical and clinical PET CT imaging of inflammation and calcification -- Clinical feasibility and monitoring of the effects of anti-inflammatory therapy in atherosclerosis.
  • 2002 HighWire
    Also available: Print – 2002
  • 2016 ClinicalKey
    [edited by] Deepak L. Bhatt.
  • 2014 Karger
    volume editors, Riccarda Granata, Jørgen Isgaard.
    Testosterone and cardiovascular risk in men / Kelly, D.M., Jones, T.H. -- Hormone therapy and venous thromboembolism among postmenopausal women / Scarabin, P.-Y. -- Cardiovascular and metabolic impact of glucocorticoid replacement therapy / Johannsson, G., Ragnarsson, O. -- Cardiovascular disease and thyroid function / Faber, J., Selmer, C. -- Hormonal alterations in heart failure : anabolic impairment in chronic heart failure -- diagnostic, prognostic and therapeutic issues / Arcopinto, M., Cittadini, A. -- Genetics of primary aldosteronism / Funder, J.W. -- Adipose tissue dysfunction and inflammation in cardiovascular disease / Wronkowitz, N., Romacho, T., Sell, H., Eckel, J. -- Potential peptides in atherosclerosis therapy / Marleau, S., Mellal, K., Huynh, D.N., Ong, H. -- Interaction between insulin-like growth factor-1 and atherosclerosis and vascular aging / Higashi, Y., Quevedo, H.C., Tiwari, S., Sukhanov, S., Shai, S.-Y., Anwar, A., Delafontaine, P. -- Ghrelin and the cardiovascular system / Tokudome, T., Kishimoto, I., Miyazato, M., Kangawa, K. -- Natriuretic peptide system and the heart / del Ry, S., Cabiati, M., Clerico, A. -- Beyond glycemic control : cardiovascular effects of incretin-based therapies / Angeli, F.S., Shannon, R.P.
  • 2001 HighWire
    edited by G. Jackson and S. Palacios.
    Also available: Print – 2001
  • 2007 Springer
    [edited by] Raymond Y. Kwong ; foreword by Peter Libby.
  • 2010 ClinicalKey
    [edited by] Warren J. Manning, Dudley J. Pennell.
    Cardiovascular Magnetic Resonance provides you with up-to-date clinical applications of cardiovascular MRI for the broad spectrum of cardiovascular diseases, including ischemic, myopathic, valvular, and congenital heart diseases, as well as great vessel and peripheral vascular disease. Editors Warren J. Manning and Dudley J. Pennell and their team of international contributors cover everything from basic MR physics to sequence design, flow quantification and spectroscopy to structural anatomy and pathology. Learn the appropriate role for CMR in a variety of clinical settings with reference to other modalities, practical limitations, and costs. With the latest information on contrast agents, MR angiography, MR spectroscopy, imaging protocols, and more, this book is essential for both the beginner and expert CMR practitioner. Covers both the technical and clinical aspects of CMR to serve as a comprehensive reference. Demonstrates the full spectrum of the application of cardiac MR from ischemic heart disease to valvular, myopathic, pericardial, aortic, and congenital heart disease. Includes coverage of normal anatomy, orientation, and function to provide you with baseline values. Discusses advanced techniques, such as interventional MR, to include essential information relevant to the specialist. Features appendices with acronyms and CMR terminology used by equipment vendors that serve as an introduction to the field. Uses consistent terminology and abbreviations throughout the text for clarity and easy reference.
  • 1982-
    editor, John H.K. Vogel.
    Status: Not Checked OutLane Catalog Record
  • 2007 Springer
    James T. Willerson ... [et al.], Eds.
    Also available: Print – 2007
  • 2015 Springer
    Sven Plein, John Greenwood, John P. Ridgway, editors.
    This updated manual is a practical and compact introductory text to CMR. It includes a didactic overview of the physics of magnetic resonance imaging, cross-referencing consistently to the clinical chapters and describing the relationship between an understanding of basic MRI physics and producing better images. Building on the first edition, the authors review the practicalities of CMR from referral to screening, set-up of the study and reporting, including numerous tips and tricks on how the reader can improve the quality of their images. The book outlines the most commonly acquired image components used in CMR and details how CMR is used in clinical practice. It covers the most common referrals for CMR imaging in a structured way with imaging protocols and case examples for each indication. Throughout the book, the authors have used graphs and tables to highlight important learning aspects. The emphasis of each chapter is on providing practical, hands-on information, making this book a key resource for all training and certifying for the use of CMR. Cardiovascular MR Manual, 2e is of use to all clinicians working in cardiology or imaging for developing a general understanding of the diagnostic information that can be obtained from CMR, the indications for referral, and the contraindications and limitations of the technique.
  • 2011 Springer
    Sven Plein, John P. Greenwood, John P. Ridgway.
    What's inside the magnet and why? -- The MRI environment -- Protons and spins: the origin of the MRI signal -- Generating a signal: RF pulses and echoes -- Relaxation times, gradient echoes, and spin echoes -- Making an image: locating and encoding signals in space -- Image space and k-space -- Imaging parameters and image attributes -- Improving SNR with surface coils and array coils -- Pulse sequences and image contrast -- Gradient echo versus spin echo -- Black blood versus bright blood imaging -- Dealing with cardiac motion: how do we image the beating heart? -- Dealing with respiratory motion -- Fast imaging: how do we speed up the image acquisition? -- Special pulse sequences for cardiac imaging -- Common artifacts -- The basics of a CMR study -- Components of CMR protocols -- Anatomy of CMR -- The CMR report -- Diseases of the aorta -- Cardiomyopathies -- Pericardial disease -- Cardiac masses -- Valvular heart disease -- Ischemic heart disease -- Basic adult congenital heart disease (ACHD) -- Pulmonary vein assessment -- Interventional cardiovascular magnetic resonance imaging.
  • 2008 Springer
    Peter G. Danias ; foreword by Warren J. Manning.
  • 2010 Springer
    Shankar Sridharan ... [et al.].
  • 2008 Springer
    by John D. Grizzard, Robert M. Judd, Raymond J. Kim.
  • 2015 Springer
    Ik-Kyung Jang, editor.
    History of OCT -- Physics of OCT -- Histology validation of OCT images -- Characterization of coronary plaques -- Basic interpretation skill -- Early stent evaluation -- Late stent changes -- Bioabsorbable stent -- Stent thrombosis -- Neoatherosclerosis -- Consensus document -- Future development. .
  • 2016 ClinicalKey
    edited by L. Maximilian Buja, Jagdish Butany.
    Anatomic considerations and examination of cardiovascular specimens (excluding devices) -- Age-related cardiovascular changes and diseases -- Vascular pathobiology : atherosclerosis and large vessel disease -- Diseases of small and medium-sized blood vessels -- Aneurysms of the aorta : ascending, thoracic and abdominal and their management -- Fundamental principles in cardiovascular genetics -- Myocardial ischemia and its complications -- Pathophysiology of heart failure and an overview of therapies -- Myocarditis -- Pathology of sudden death, cardiac arrhythmias and conduction system -- Cardiomyopathies -- Valvular heart disease -- Cardiac valve replacement and related interventions -- The pathology of cardiovascular interventions and devices for coronary artery disease, vascular disease, heart failure, and arrhythmias -- Congenital heart disease : pathology, natural history, and interventions -- The pericardium and its diseases -- Pathology of cardiac transplantation -- Toxins and the heart -- Tumors of the cardiovascular system : heart and blood vessels -- Forensic aspects of cardiovascular pathology.
  • 2009 Springer
    Derek S. Wheeler, Hector R. Wong, and Thomas P. Shanley (eds.).
  • 2013 ClinicalKey
    Achilles J. Pappano, Withrow Gil Wier.
    Overview of the circulation and blood -- Excitation : the cardiac action potentia -- Automaticity : natural excitation of the heart -- The cardiac pump -- Regulation of the heartbeat -- Hemodynamics -- The arterial system -- The microcirculation and lymphatics -- The peripheral circulation and its control -- Control of cardiac output: coupling of heart and blood vessels -- Coronary circulation -- Special circulations -- Interplay of central and peripheral factors that control the circulation.
    Also available: Print – 2013
  • 2007
    Matthew N. Levy, Achilles J. Pappano.
    Status: Not Checked OutLane Catalog Record
  • 2010 AccessMedicine
    David E. Mohrman, Lois Jane Heller.
  • 2006
    David E. Mohrman, Lois Jane Heller.
  • 2014 AccessMedicine
    David E. Mohrman, PhD, Lois Jane Heller, PhD.
    Overview of the cardiovascular system -- Characteristics of cardiac muscle cells -- The heart pump -- Measurements of cardiac function -- Cardiac abnormalities -- The peripheral vascular system -- Vascular control -- Hemodynamic interactions -- Regulation of arterial pressure -- Cardiovascular responses to physiological stresses -- Cardiovascular function in pathological situations -- Answers to study questions.
  • 2007 Springer
    Joep Perk ... [et al.], editors.
    Introduction / edited by Peter Mathes -- Exercise testing in heart disease / edited by Helmut Gohlke -- Exercise training in heart disease / edited by Helmut Gohlke -- Nutrition / edited by Catherine Monpère -- Tobacco addiction / edited by Irene Hellemans -- Psychological and behavioral support / edited by Hannah McGee -- Social and caring support / edited by Philippe Sellier -- Adapted programs for special groups / edited by Hugo Saner -- Pharmacotherapy, organization, evaluation / edited by Joep Perk.
  • 2006 Springer Protocols
    edited by Fernando Vivanco.
  • 2005 Springer
    H. Mori, H. Matsuda (eds.).
  • 2006 Springer
    edited by Gerard Pasterkamp and Dominique P.V. de Kleijn.
  • 2007 HighWire
    guest editor,Frank Selke.
  • 2006
    Frank Selke, guest editor.
  • 2008 HighWire
    guest editor, John S. Ikonomidis.
  • 2002 Cold Spring Harb Lab Press
    SU Catalog (SearchWorks) Click LINK above for Print location/circulation status.
    Development of the cardiovascular system -- Transcription factors in cardiovascular development -- Vascular biology -- Tumor angiogenesis -- Genetics and genomics of the cardiovascular system -- Regulation of the heart -- Heart disease and failure -- Hypertension, atherosclerosis, and lipid homeostasis -- Repairing the cardiovascular system -- Author index -- Subject index.
  • 2013 ClinicalKey
    [edited by] Elliott M. Antman, Marc S. Sabatine ; section editors, James de Lemos [and others].
    Tools for Assessment of Cardiovascular Tests and Therapies -- New Drug Development -- Device Development for Cardiovascular Therapeutics: Concepts and Regulatory Implications -- Pharmacogenetics -- Systems of Health Care -- Global Cardiovascular Therapy -- Pharmacologic Options for Treatment of Ischemic Disease -- Stable Ischemic Heart Disease/Chronic Stable Angina -- Non-ST-Segment Elevation Acute Coronary Syndromes -- ST-Segment Elevation Myocardial Infarction -- Advances in Coronary Revascularization -- Pharmacologic Management of Heart Failure in the Ambulatory Setting -- Implantable Devices for the Management of Heart Failure -- Strategies for Management of Acute Decompensated Heart Failure -- Cardiac Transplantation and Circulatory Support Devices -- Regenerative Therapy for Heart Failure -- Hypertrophic, Restrictive, and Infiltrative Cardiomyopathies -- Clinical Pharmacology of Antiarrhythmic Drugs -- Pharmacologic Management of Supraventricular Tachycardias -- Atrial Fibrillation -- Nonpharmacologic Treatment of Tachyarrhythmias -- Role of Implantable Cardioverter-Defibrillators in Primary and Secondary Prevention of Sudden Cardiac Death -- Treatment of Ventricular Tachycardia and Cardiac Arrest -- Drugs for Elevated Low-Density Lipoprotein Cholesterol -- Therapy to Manage Low High-Density Lipoprotein Cholesterol and Elevated Triglycerides -- Cardiovascular Disease and Lifestyle Modification -- Steps Beyond Diet and Drug Therapy for Severe Hypercholesterolemia -- Initial Evaluation and Approach to the Patient with Hypertension -- Pharmacologic Management of Hypertension -- Endocrine Causes of Hypertension -- Resistant Hypertension -- Hypertensive Crisis -- Hypertension in Pregnancy -- Management of Hypertension in Children and Adolescents -- Peripheral Artery Disease -- Cerebrovascular Disease -- Renal Artery Stenosis -- Pulmonary Embolism and Deep Vein Thrombosis -- Treatment of Pulmonary Arterial Hypertension -- Aortic Disease -- Pharmacologic Options for Treating Cardiovascular Disease During Pregnancy -- Care for Adults with Congenital Heart Disease -- Prevention and Treatment of Infective Endocarditis -- Treatment of Pericardial Disease -- Optimal Timing of Surgical and Mechanical Intervention in Native Valvular Heart Disease -- Surgery for Valvular Heart Disease -- Percutaneous Treatment for Valvular Heart Disease -- Manifestations, Mechanisms, and Treatment of HIV-Associated Cardiovascular Disease -- Rehabilitation of the Patient with Cardiovascular Disease.
  • v. 1, 1979
    Raymond E. Phillips.
    Status: Not Checked OutLane Catalog Record
    v. 1. Circulation.
  • 2012
    [edited by] David K. Stevenson, M. Jeffrey Maisels, Jon F. Watchko.
    Status: Not Checked OutLane Catalog Record
    "Care of the Jaundiced Neonate focuses exclusively on the scientific underpinnings of jaundice, as well as the care of the jaundiced neonate. Edited by three of the field's most respected neonatal care experts, the book uniquely explains how the imbalance between bilirubin production and elimination leads to jaundice--and that hazardous levels of unconjugated bilirubin can cause kernicterus, or brain damage. In addition, you'll find the most current and clinically relevant perspectives on the physiology, genetics, and treatment of neonatal jaundice and related hemolytic conditions. -- FEATURES -- Covers all aspects of neonatal jaundice--from the biochemistry of bilirubin production to kernicterus -- Begins with an in-depth examination of the complex gene-environment interactions of bilirubin-induced neurotoxicity and its role in neonatal jaundice -- Surveys bilirubin production and measurement, its various fractions, and the metabolism and transport of bilirubin -- Selected chapters highlight the physiology and epidemiology of neonatal unconjugated hyperbilirubinemia; bilirubin toxicity; prevention, screening, and postnatal management; phototherapy and other treatments; and prevention-related public policy. -- Concluding chapter provides an overview of the key issues surrounding the incidence of neonatal jaundice in low-middle income countries -- Includes informative review of risk assessment and treatment with phototherapy and other modalities provide key approaches to the effective clinical management of neonatal hyperbilirubinemia." -- [Publisher-supplied data]
  • 2010 Springer
    Nancy J. Johnson, Lane P. Johnson, editors.
    Who are the uninsured? / Howard Eng -- Why are people uninsured? ; The culture of poverty and the uninsured ; Health disparities and the uninsured ; Providers of care for the uninsured ; Chronic disease and the uninsured ; Medical homes (preferably "health home") and the uninsured / Nancy J. Johnson -- Medication assistance for the uninsured / Nancy J. Johnson and Janet S. Smith -- Medically uninsured refugees and immigrants / Lane P. Johnson -- Medically uninsured and the homeless / Jennifer Vanderleest -- Care of underserved people with mental illness / Francisco A. Moreno and Sarah Heron -- Medically uninsured older Americans / Lynne Tomasa -- Direct caregivers association: an option for a rapidly growing aging population? / Judith B. Clinco -- The rural uninsured ; Dental care for the uninsured / Lane P. Johnson -- Uninsured children at school / Fran Bartholomeaux and Nancy J. Johnson -- Building community collaborations around care for the uninsured / Nancy J. Johnson -- Information technology and medically uninsured / Theresa Cullen -- The role of government in providing health care to the uninsured / James E. Dalen -- Think nationally, act locally / Lane P. Johnson.
  • Freedman, Toby.
    Status: Not Checked OutLane Catalog Record
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
    Status: Not Checked OutLane Catalog Record
  • *Freedman, Toby.
    Status: Not Checked OutLane Catalog Record
  • *Freedman, Toby.
  • *Freedman, Toby.
    Status: Not Checked OutLane Catalog Record
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • *Freedman, Toby.
  • 2008
    Toby Freedman.
    Status: Not Checked OutLane Catalog Record
  • 2006 ebrary
    Susan Echaore-McDavid.
    Pre-K-12 teachers -- Pre-K-12 teaching specialists -- Postsecondary educators -- Overseas teachers -- School administrators -- Higher education administrators -- Educational assistants -- School classified staff -- Classified staff in higher education -- School specialists in student services and special education-related services -- Counselors -- Curriculum and instructional developers -- Educational and instructional technology specialists -- Librarians -- Independent instructors -- Health educators -- Fitness, recreation, and sports professionals -- Environmental educators and animal trainers -- Employee training specialists -- Appendixes.
  • 2015 Springer
    Charalambos Panayiotou Charalambous.
    The transition from medical school to being a practicing junior doctor is challenging. It requires knowledge and clinical skills but also the ability to efficiently function in the workplace. At the same time postgraduate professional development in gaining clinical experience, passing postgraduate exams, under-taking research or audit, and publishing become essential for career progression. One soon realizes that being a doctor is not just a profession but a way of life. This book presents some well-known ℓ́ℓpearlsℓ́ℓ as how to improve your day to day workplace performance, be efficiently productive, be an inherent part of the team, how to shine and impress. Advice is also given as how to prepare for postgraduate exams, develop essential technical skills, apply for the next post, successfully participate in research and audit, publish, manage, lead, teach, and train. This generic guidance can be of use for those aspiring to become a generalist or subspecialty doctor and can be of value in whichever part of the world you end up practicing in.
  • Status: Not Checked OutLane Catalog Record
  • 2011 businesorientedwomen.com
  • 2011 Business Oriented Women
  • 1996 NAP
    Committee on Science, Engineering, and Public Policy, National Academy of Sciences, National Academy of Engineering, Institute of Medicine.
    1. What Are Your Career Goals? -- 2. How Can You Meet Your Career Goals? -- 3. What Survival Skills and Personal Attributes Do You Need to Succeed? -- 4. What Education Do You Need to Reach Your Career Goals? -- 5. How Do You Get the Job That is Right for You? -- 6. The Responsibility is Yours -- Appendix A Discussion of Scenarios -- Appendix B Skills and Attributes that Contribute to Success in Science or Engineering.
  • 2003 Wiley
    edited by Peter D. Stonier.
    I. Background to medicines research and development -- 1. Pharmaceutical medicine: A specialist discipline / Felicity Gabbay -- 2. The contribution of academic clinical pharmacology to medicines research / Charles F. George -- 3. A career in drug discovery / David Ellis -- II. Careers in pre-clinical and clinical research -- 4. A career in clinical pharmacology / Roger Yates -- 5. Career opportunities for physicians in the pharmaceutical industry / Bert Spilker -- 6. The clinical research associate / Gareth Hayes -- 7. Clinical trial administrator and study site co-ordinator: Key roles in clinical research / Nicola Murgatroyd, Caroline Crockatt and Gareth Hayes -- 8. Statisticians in the pharmaceutical industry / Christopher Hilton and Trevor Lewis -- 9. Careers in data management -- 10. Working in a contract research organisation / Jane Barrett -- III. Careers in sales and marketing -- 11. A career in product management / Roy Carlisle -- 12. A career in medical sales and medical sales management / Roy Carlisle -- IV. General careers with the pharmaceutical industry -- 13. The role of the pharmacist in healthcare / David Jordan -- 14. Careers for nurses with the pharmaceutical industry / Joyce E. Kenkre -- 15. The toxicologist in pharmaceutical medicine / Geoffrey Diggle -- 16. A career in clinical quality assurance / Rita Hattemer-Apostel -- 17. A career in product registration and regulatory affairs / Pat Turmer -- 18. Careers in drug safety and pharmacovigilance / Peter Barnes -- 19. Careers in medical information / Janet Taylor -- 20. Medical writing as a career / Brenda M. Mullinger -- 21. Career opportunities in medicines regulation: The medical assessor / Nigel Baber -- 22. Pharmaceutical law: A growing legal specialty / Ian Dodds-Smith -- 23. Industry careers for pharmacoeconomists / Nick Bosanquet -- 24. Consultant in pharmaceutical medicine / Brian Gennery -- V. Career progression -- 25. Landing that job: Recruitment, CVs and interviews / Sue Ransom -- 26. Career development in pharmaceuticals / Roger D. Stephens -- 27. Opportunities for education and training in the pharmaceutical industry / Peter D. Stonier and Gareth Hayes.
  • 2007 Springer
    edited by Marja Vaarama, Richard Pieper and Andrew Sixsmith.
  • 2012 OSO
    Eileen Boris and Jennifer Klein.
    This title is the definitive history of care work and its surprisingly central role in the American labour movement and class politics from the New Deal to the present. The authors create a narrative of the home care industry that interweaves four histories and considers their impact on today's most dynamic social movements.
  • 2013 Springer
    editor-in-chief: Siegfried Zabransky ; contributors: Miguel Alejandre Alcázar...[et al.].
    Care for Children Born Small for Gestational Age is a comprehensive handbook that serves to synthesize the extensive recent literature in the area to provide a practical resource aimed at a wide range of healthcare professionals, including obstetricians, midwives, neonatologists, and primary care physicians. This comprehensive handbook includes an in-depth survey of the prevention, diagnosis, treatment and long-term monitoring of children born small for gestational age, as well as related conditions such as intrauterine growth restriction, metabolic syndrome and type 2 diabetes. Additionally, the short and long-term psychiatric and social consequences of this condition are addressed.
  • 2015
    edited by Mignon Duffy, Amy Armenia, and Clare L. Stacey.
    "A nurse inserts an I.V. A personal care attendant helps a quadriplegic bathe and get dressed. A nanny reads a bedtime story to soothe a child to sleep. Every day, workers like these provide critical support to some of the most vulnerable members of our society. Caring on the Clock provides a wealth of insight into these workers, who take care of our most fundamental needs, often at risk to their own economic and physical well-being. Caring on the Clock is the first book to bring together cutting-edge research on a wide range of paid care occupations, and to place the various fields within a comprehensive and comparative framework across occupational boundaries. The book includes twenty-two original essays by leading researchers across a range of disciplines--including sociology, psychology, social work, and public health. They examine the history of the paid care sector in America, reveal why paid-care work can be both personally fulfilling but also make workers vulnerable to burnout, emotional fatigue, physical injuries, and wage exploitation. Finally, the editors outline many innovative ideas for reform, including top-down and grassroots efforts to improve recognition, remuneration, and mobility for care workers. As America faces a series of challenges to providing care for its citizens, including the many aging baby boomers, this volume offers a wealth of information and insight for policymakers, scholars, advocates, and the general public"--Provided by publisher. "Caring on the Clock is the first book to bring together cutting-edge research on a wide range of paid care occupations, placing the various studies within a comprehensive and comparative framework. The book includes twenty-two original essays by leading researchers across a range of disciplines--including sociology, psychology, social work, and public health--and provides a wealth of insight into these workers, who take care of our most fundamental needs, often at risk to their own economic and physical well-being"--Provided by publisher.
  • 2012
    Erin Girard.
    Cardiac C-arm CT is a valuable imaging modality that can provide three-dimensional images of the heart during an interventional procedure. As the technology advances to provide better image quality and faster acquisition times, the potential clinical uses increase. Visualization of myocardial defects could directly impact the guidance, procedure time, and outcome of various interventional procedures. In this work, I developed protocols to optimize low-contrast detectability for cardiac C-arm CT and performed in vivo studies to validate using C-arm CT for imaging myocardial necrosis during a cardiac interventional procedure. Initial in vivo investigations were used to evaluate the contrast injection protocol for ideal timing, dilution, catheter type, and injection location. Additionally, x-ray parameters including filtration, kVp, dose, and collimation were optimized for low-contrast detectability and minimization of artifacts. A 4 sweep x 5 s, ECG-gated imaging protocol using low energy (70-90 kVp) and high dose (1.2 [mu]Gy/projection) optimizes low contrast detectability, while collimation around the heart improves SNR by reducing scatter. Images acquired both in vivo and in a slab phantom show that tight collimation and beam filtration result in improved SNR and a reduction of shading artifacts. Visualization of radiofrequency ablation lesions using contrast enhanced C-arm CT during the procedure provides a direct assessment of adequate lesion formation and may circumvent complications associated with cardiac ablation procedures. An in vivo validation study was completed in 9 swine by comparing lesion dimensions measured in C-arm CT images and pathology specimens. All ablation lesions were visualized and lesion dimensions, as measured on C-arm CT, correlated well with postmortem tissue measurements using triphenyltetrazolium chloride (TTC) staining (mean difference 1D dimensions: 0.09 ± 1.04 mm, area: -0.71 ± 5.86 mm2). C-arm CT visualization of myocardial infarction (MI) in the catheterization lab could furnish early prognostic information for risk stratification as well as provide 3D images for guidance of stem cell or ablation therapies. A porcine model using balloon occlusion in the coronary artery was used to study visualization of acute and subacute MI in 12 swine. Contrast enhanced C-arm CT imaging was performed the day of infarct creation or 4 weeks after infarct creation and the volume of the infarct was compared against pathology to validate the visualization of infarction. Acute MI is best visualized at 1 minute post contrast injection as a region of combined hyper- and hypoenhancement whereas subacute MI appears as a region of hyperenhancement with peak contrast enhancement at 5 minutes post contrast injection. C-arm CT infarct volumes compared well with TTC staining (mean difference acute: -0.5 cm3, subacute: -0.7cm3). In conclusion, cardiac C-arm CT with contrast and imaging protocols optimized for low-contrast detectability has been established as a consistent and reliable technique for imaging myocardial necrotic tissue in the interventional suite.
  • 2014 CRCnetBASE
    editors, Benjamin T. Wall, Craig Porter.
    "Carnitine Metabolism and Human Nutrition offers a contemporary and in-depth look at the biological effects of carnitine metabolism and its application to clinical and sports nutrition, based on decades of robust scientific enquiry. It gathers and distills key results of the last 20 years of carnitine research to provide an invaluable reference tool for students, researchers, and clinicians. This book addresses the importance of carnitine in skeletal muscle fuel metabolism, the complexities and importance of muscle carnitine transport, and the metabolic insight that has been gained from experiments manipulating muscle carnitine stores. The authors cover the potential application of carnitine supplementation in specific clinical populations and the role of carnitine as an ergogenic aid for athletes. They also provide a comprehensive mechanistic overview of skeletal muscle insulin resistance, including the role of carnitine shuttle systems in the metabolic abnormalities associated with obesity and the metabolic syndrome. Carnitine Metabolism and Human Nutrition provides you with a comprehensive and up-to-date look at the properties and underlying metabolic biochemistry of carnitine. The book provides contributions from leading international scientists, each a pioneer in their chosen study of carnitine metabolism or its application to human nutrition."--Page [4] of cover.
  • 2010 CRCnetBASE
    edited by John T. Landrum.
    "Carotenoids are of great interest due to their essential biological functions in both plants and animals. However, the properties and functions of carotenoids in natural systems are surprisingly complex. With an emphasis on the chemical aspects of these compounds, Carotenoids: Physical, Chemical, and Biological Functions and Properties presents a broad overview and recent developments with respect to understanding carotenoid structure, electronic and photochemical properties, and the use of novel analytical methods in the detection and characterization of carotenoids and their actions. The text also explores LC/MS and LC/MS/MS techniques as well as new applications of PCR and molecular biology methodologies"--Book jacket.
  • 2013 Springer
    Sherry A. Tanumihardjo, editor.
    Carotenoids and Human Health provides an introduction to food sources and metabolism. Written by experts in their fields and including the most up-to-date information, this volume serves as an in-depth guide to studies that have been performed in humans and observations that have been made in population level assessments. Special emphasis is given to associations with disease, as well as the importance of carotenoids internationally, specifically as a source of vitamin A for the world. Comprehensive and easy to use, Carotenoids and Human Health is a very useful resource for nutritionists, registered dieticians, medical students, and graduate students.
  • 2014 CRCnetBASE
    edited by John T. Landrum, John M. Nolan.
    "This book outlines the pathological conditions of the central retina where the macular pigment is known to have its greatest involvement in protection against photooxidative damage. The book focuses on the nature of the macular carotenoids, their transport and accumulation within the retina, and their influence on the etiology of retinal diseases. It also includes chapters that provide readers an understanding of the epidemiology and pathology of these diseases and the known factors which contribute to them"--Provided by publisher.
  • 2005 CRCnetBASE
    editors, Lester Packer ... [et al.].
  • 2013 CRCnetBASE
    edited by Olaf Sommerburg, Werner Siems, and Klaus Kraemer.
    Hepatic retinoid metabolism : what is known and what is not / Jason J. Yuen, Jian Zhang Yang and William S. Blaner -- Metabolism of vitamin A in white adipose tissue and obesity / Shanmugam M. Jeyakumar ... [et al.] -- Retinoids in the treatment of psoriasis / Neil Borkar, Alan Menter -- Age-related macular degeneration and carotenoids / Nilesh Kalariya, Werner G. Siems, Frederik van Kuijk -- Lutein, zeaxanthin and vision across the lifespan / Billy R. Hammond, Jr. -- Assuring vitamin A adequacy to prevent eye and ear disorders / Tripper Sauer, Susan Emmett, Keith P. West, Jr. -- Disturbed accumulation and abnormal distribution of macular pigment in retinal disorders / Tos TJM Berendschot, Peter Charbel Issa, Thomas Theelen -- Retinol and otitis media / Akeem Olawale Lasisi -- Carotenoids and mutagenesis / P. M. Eckl ... [et al.] -- Carotenoids and vitamin A in lung cancer prevention / Anita Ratnasari Iskandar, Xiang-Dong Wang -- Is the effect of [Beta]-carotene on prostate cancer cells dependent on their androgen sensitivity? / Joanna Dulinska-Litewka ... [et al.] -- Carotenoid intake and supplementation in cancer : pro and con / W.G. Siems ... [et al.] -- Vitamin A in lung development and function / Hans-Konrad Biesalski -- Vitamin A and carotenoids in lung diseases / Olaf Sommerburg, Werner Siems -- Chemopreventive effects of astaxanthin on inflammatory bowel disease and inflammation-related colon carcinogenesis / Masashi Hosokawa, Yumiko Yasui -- Carotenoids in laboratory medicine / Ingolf Schimke, Michael Vogeser -- Supply of vitamin A in developing countries / Klaus Kraemer -- Vitamin A intakes are below recommendations in a significant proportion of the population in the western world / Hans-Konrad Biesalski, Barbara Trösch, Petra Weber -- Critical appraisal of vitamin A supplementation program in India / Dechenla Tshering Bhutia, Saskia De Pee -- Consequences of common genetic variations on SS-carotene cleavage for vitamin A supply / Georg Lietz, Anthony Oxley, Christine Boesch-Saadatmandi.
  • 1992 ScienceDirect
    edited by Lester Packer.
    Also available: Print – 1992
  • 2009 Springer
    edited by Jacqueline Saw.
  • 2007
    Christopher M. Loftus.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    edited by Emmanuel Camus, Luc Van Overstraeten.
    Nowadays, it is established that carpal ligamentary lesions may lead to instability and then to carpal arthritis. However, the variety of anatomopathological classifications and the multiplicity of surgical repair techniques reflect the difficulty of conceiving this ligamentary pathology. The clinical analysis and traditional investigation techniques face the complexity of the wrist. Its mechanical complexity is due to the number of synchronized bones in every movement of the hand. The clinical analysis of the wrist is insufficient to precisely measure the mobility of each carpal bone. Paraclinical examinations are also significant for clinical diagnosis. The tools available today range from X-rays to arthroscopy, including arthroCTscan and soon MRI. As concerns repair techniques, their diversity must not hide the fact that a biomechanical and physiological principle is involved and must be identified. This book is the result of a reflection of an expert group in the field of wrist pathology. It attempts to analyze, understand, explain and make comprehensible, if not obvious, the reflections that each practitioner should employ during the diagnosis and treatment of carpal ligamentary lesions. The focus is consciously not on degenerative carpal pathology, which usually enjoys more visibility. We hope that readers will benefit from the fact that fragmented pieces of knowledge are gathered in a single work, that they will find in this beginning synthesis inspiring to rethink a difficult and sometimes thankless surgery and to further the surgical advances of the 21st century.
  • 2007 Springer
    R. Luchetti, P. Amadio, eds.
  • 2010 ClinicalKey
    Alain Carpentier, David H. Adams, Farzan Filsoufi ; illustrations by Alain Carpentier and Marcia Williams.
    Section 1. Fundamentals -- section 2. Mitral valve reconstruction -- section 3. Tricuspid valve reconstruction -- section 4. Aortic valve reconstruction -- section 5. Disease-specific approach -- section 6. Transfer of knowledge.
  • 2015 ClinicalKey
    [edited by] Michael G. Newman, Henry H. Takei, Perry R. Klokkevold ; editor emeritus, Fermin A. Carranza.
    Anatomy of the Periodontium -- Aging and the Periodontium -- Classification of Diseases and Conditions Affecting the Periodontium -- Fundamentals in the Methods of Periodontal Disease Epidemiology -- Periodontal Pathogenesis -- Genetic Susceptibility to Periodontal Disease -- The Role of Dental Calculus and Other Local Predisposing Factors -- Biofilm and Periodontal Microbiology -- Molecular Biology of Host-Microbe Interactions -- Smoking and Periodontal Disease -- Influence of Systemic Conditions -- Impact of Periodontal Infection on Systemic Health -- Defense Mechanisms of the Gingiva -- Gingival Inflammation -- Clinical Features of Gingivitis -- Gingival Enlargement -- Acute Gingival Infections -- Gingival Disease in Childhood -- Desquamative Gingivitis -- The Periodontal Pocket -- Bone Loss and Patterns of Bone Destruction -- Periodontal Response to External Forces -- Chronic Periodontitis -- Necrotizing Ulcerative Periodontitis -- Aggressive Periodontitis -- Pathology and Management of Periodontal Problems in Patients with Human Immunodeficiency Virus Infection -- Masticatory System Disorders that Influence the Periodontium -- Sleep-Disordered Breathing -- Clinical Diagnosis -- Significance of Clinical and Biologic Information -- Radiographic Aids in the Diagnosis of Periodontal Disease -- Clinical Risk Assessment -- Determination of Prognosis -- Rationale for Periodontal Treatment -- The Treatment Plan -- Conscious Sedation -- Periodontal Treatment of Medically Compromised Patients -- Periodontal Therapy in the Female Patient -- Periodontal Treatment for Older Adults -- Treatment of Aggressive and Atypical Forms of Periodontitis -- Treatment of Acute Gingival Disease -- Treatment of Periodontal Abscess -- Diagnosis and Management of Endodontic-Periodontic Lesions -- Phase I Periodontal Therapy -- Plaque Biofilm Control for the Periodontal Patient -- Scaling and Root Planing -- Sonic and Ultrasonic Instrumentation and Irrigation -- Anti-infective Therapy -- Host Modulation -- Occlusal Evaluation and Therapy -- Adjunctive Role of Orthodontic Therapy -- Pathologic Tooth Migration: A Case Report * -- Breath Malodor -- Phase II Periodontal Therapy -- Periodontal and Periimplant Surgical Anatomy -- General Principles of Periodontal Surgery -- Gingival Surgical Techniques -- The Periodontal Flap -- Treatment of Gingival Enlargement -- The Flap Technique for Pocket Therapy -- Resective Osseous Surgery -- Periodontal Regeneration and Reconstructive Surgery -- Furcation: Involvement and Treatment -- Periodontal Plastic and Esthetic Surgery -- Periodontal Microsurgery -- Recent Advances in Surgical Therapy: Lasers in Periodontal Therapy -- Preparation of the Periodontium for Restorative Dentistry -- Restorative Interrelationships -- Multidisciplinary Approach to Dental and Periodontal Problems -- Supportive Periodontal Treatment -- Results of Periodontal Treatment -- Periimplant Anatomy, Biology, and Function -- Clinical Evaluation of the Implant Patient -- Diagnostic Imaging for the Implant Patient -- Biomechanics, Prosthetic Considerations, and Treatment Planning -- Basic Implant Surgical Procedures -- Localized Bone Augmentation and Implant Site Development -- Advanced Implant Surgical Procedures -- Esthetic Management of Difficult Cases (Minimally Invasive Approach) -- Technologic Advances in Implant Surgery: Dental Implant Microsurgery-Immediate Placement -- Technologic Advances in Implant Surgery: Piezoelectric Bone Surgery -- Technologic Advances in Implant Surgery: Computer-Assisted Implant Surgery -- Implant-Related Complications and Failures -- Supportive Implant Treatment -- Results of Implant Treatment -- Atlas of Periodontal Diseases -- Introduction to Evidence-Based Decision Making -- Assessing Evidence -- Electronic Dental Records and Decision Support Systems -- Locally Delivered, Controlled-Release Antimicrobials -- Locally Delivered, Controlled-Release Antimicrobials: Drug Development and Clinical Research.
  • 2010
    Marta Gaia Zanchi.
    Accurate control of the radio-frequency (RF) electromagnetic fields in Magnetic Resonance Imaging (MRI) is necessary to ensure patient safety and provide high-quality diagnostic capabilities. Precise control is however becoming increasingly difficult to achieve, given the recent trends toward high fields and transmitter array systems. At high fields, imaging is performed in a frequency regime where the wavelength is on the order of, or smaller than, the dimensions of the human body. This leads to prominent wave behavior, non-uniform field patterns, and increased power deposition. Multi-element transmitter array systems with independent phase and amplitude control of their elements support methods that can mitigate these problems. However, in turn, they demand high fidelity RF reproduction and may lead to undesired electromagnetic interactions between elements of the arrays and with interventional devices. Frequency-offset Cartesian feedback can be used to address all of these issues. In combination with the use of polyphase error amplifiers (to implement a low-IF control bandwidth), Cartesian feedback can be used with MRI power amplifiers and transmit coils to increase the fidelity of RF reproduction, without the in-bandwidth DC-offsets and quadrature mismatches that may lead to imaging artifacts such as bright spots and ghosting. In addition, the control system, which includes autotuning circuitry for stability and vector multipliers circuitry for feedback manipulation, can be used to tune the series output impedance of these amplifiers, thereby reducing the likelihood of interactions between elements of transmit array systems. Furthermore, a miniaturized variation of the control system (called Active Cable Trap) can be used on guidewires to suppress undesired currents elicited by coupling with the RF fields of the transmit coils. In an era of rapid progress in high field MRI for clinical applications, the frequency offset Cartesian feedback method and system thus promises to address many of the challenges faced by designers of multi-element transmitter array systems.
  • 2011 Karger
    4th ESPE Advanced Seminar in Developmental Endocrinology, Stockholm, June 30-July 1, 2010 ; volume editors, Cecilia Camacho-Hübner, Ola Nilsson, Lars Sävendahl.
    Chondrocyte proliferation and differentiation / Wuelling, M., Vortkamp, A. -- Local regulation of growth plate cartilage / Spth, S.-S. ... [et al.] -- Growth plate senescence and catch-up growth / Lui, J.C., Nilsson, O., Baron, J. -- Endocrine regulation of longitudinal bone growth / Wit, J.M., Camacho-Hübner, C. -- Estrogen signaling in growth plate cartilage / Karimian, E., Svendahl, L. -- Methods to study cartilage and bone development / Andrade, A.C. ... [et al.] -- Fibroblast growth factor-23 and phosphorus metabolism / Tiosano, D. -- Molecular defects causing skeletal dysplasias / Mkitie, O. -- Allele-specific gene silencing in osteogenesis imperfecta / Ljunggren, Ö. ... [et al.] -- Stem cells in skeletal physiology and endocrine diseases of bone / Bianco, P., Sacchetti, B., Riminucci, M. -- Cartilage tissue engineering / Moreira-Teixeira, L.S. ... [et al.].
  • 2004 Springer Protocols
    v. 2 Springer Protocols
    edited by Massimo Sabatini, Philippe Pastoureau, Frédéric De Ceuninck.
    A simple and reliable assay of proteoglycan synthesis by cultured chondrocytes -- Assays of proteoglycan and collagen degradation in cultures of rabbit cartilage explants -- Production of antibodies against degradative neoepitopes in aggrecan -- Immunoassays for collagens in chondrocyte and cartilage explant cultures -- Detection of apoptosis in cartilage in situ and in isolated chondrocytes -- Expression, activity, and regulation of MAP kinases in cultured chondrocytes -- Mechanical loading of chondrocytes embedded in 3D constructs: in vitro methods for assessment of morphological and metabolic response to compressive strain -- In vitro physical stimulation of tissue-engineered and native cartilage -- v. 1. Cellular and molecular tools. Culture and phenotyping of chondrocytes in primary culture -- Culture of chondrocytes in alginate beads -- Immortalization of human articular chondrocytes for generation of stable, differentiated cell lines -- Culture of immortalized chondrocytes and their use as models of chondrocyte function -- Generation of pluripotent stem cells and their differentiation to the chondrocytic phenotype -- Semiquantitative analysis of gene expression in cultured chondrocytes by RT-PCR -- Quantification of mRNA expression levels in articular chondrocytes with PCR technologies -- RNA extraction from cartilage -- Gene expression analysis in cartilage by in situ hybridization -- Analysis of differential gene expression in healthy and osteoarthritic cartilage and isolated chondrocytes by microarray analysis -- High-efficiency nonviral transfection of primary chondrocytes -- In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors -- Changes of chondrocyte metabolism in vitro: an approach by proteomic analysis -- Analysis of chondrocyte functional markers and pericellular matrix components by flow cytometry -- v. 2. Structure and in vivo analysis. Generation and use of transgenic mice as models of osteoarthritis -- Development and clinical application in arthritis of a new immunoassay for serum type IIA procollagen NH2 propeptide -- Histological and immunohistological studies on cartilage -- Histochemical visualization of the cartilage hyaladherins using a biotinylated hyaluronan oligosaccharide bioaffinity probe -- Methods for cartilage and subchondral bone histomorphometry -- Laser-mediated microdissection as a tool for molecular analysis in arthritis -- Analysis of protein distribution in cartilage using immunofluorescence and laser confocal scanning microscopy -- Molecular and biochemical assays of cartilage components -- Mechanical characterization of native and tissue-engineered cartilage -- Noninvasive study of human cartilage structure by MRI -- High-resolution MRI techniques for studies in small-animal models -- High-resolution imaging of osteoarthritis using microcomputed tomography -- High-resolution ultrasonograpy for analysis of age- and disease-related cartilage changes -- Evaluation of cartilage composition and degradation by high-resolution magic-angle spinning nuclear magnetic resonance -- Pulsed-field gradient-nuclear magnetic resonance (PFG NMR) to measure the diffusion of ions and polymers in cartilage: applications in joint diseases -- Dynamics of collagen in articular cartilage studied by solid-state NMR methods -- Computerized protocol for anatomical and functional studies of joints.
    Also available: Print – v. 1-2, 2004.
  • 2011 Springer
    Thomas M. Link, editor.
  • 2015 Springer
    Gian Luigi Canata, C. Niek van Dijk, editors.
    This booklet, published in cooperation with ISAKOS, is a concise, up-to-date guide and reference on the treatment of cartilage lesions of the ankle that will be of practical clinical value for specialists in sports medicine and sports traumatology. Different techniques and the management of various lesions are described step by step, guiding the practitioner through the entire spectrum of care from evaluation of the injury to successful recovery. Chondral and osteochondral lesions of the talus can present as a consequence of repetitive ankle injuries, causing chronic pain, recurrent swelling, and weakness and stiffness of the ankle joint. An accurate early diagnosis is required, using clinical evaluation, imaging techniques, and arthroscopy of the ankle. In acute and non-displaced chondral and osteochondral lesions, conservative treatment is the mainstay. Surgery is recommended for unstable and persistent lesions and consists in several techniques focused on regeneration of the cartilage. Returning to play is possible after testing balance and proprioception, strength, range of motion, and agility.
  • 2007 Springer
    edited by Riley J. Williams III ; with forewords by Lars Peterson and Brian J. Cole.
    Articular cartilage : structure, biology, and function / Kyle R. Flik ... [et al.] -- Evaluating outcome following cartilage procedures / Robert G. Marx -- MRI and articular cartilage : evaluating lesions and postrepair tissue / Hollis G. Potter, Li F. Foo, and Andrew D. Pearle -- Decision making in cartilage repair procedures / Riley J. Williams III and Robert H. Brophy -- Nonoperative treatment options for symptomatic cartilage lesions / Marc C. Drakos and Answorth A. Allen -- Marrow stimulation and microfracture for the repair of articular cartilage lesions / Daniel J. Solomon, Riley J. Williams III, and Russell F. Warren -- Cartilage repair with chitosan-glycerol phosphate-stabilized blood clots / Michael D. Buschmann ... [et al.] -- Autologous osteochondral transplantation / Anthony Miniaci, Clinton Jambor, and Frank A. Petrigliano -- Articular cartilage resurfacing using synthetic resorbable scaffolds / Riley J. Williams III and Gabriele G. Niederauer -- Autologous chondrocyte implantation / Deryk G. Jones and Lars Peterson -- Osteochondral allograft transplantation / Joseph Yu and William D. Bugbee -- Matrix-induced autologous chodrocyte implantation / David Wood and Ming Hao Zheng -- Cell-based cartilage repair using the hyalograft transplant / Maurilio Marcacci ... [et al.] -- Allogeneic chodrocyte-based cartilage repair using alginate beads / Peter C.M. Verdonk ... [et al.] -- The role of knee osteotomy in the setting of articular cartilage repair / Keith M. Baumgarten and Thomas L. Wickiewicz -- Management of osteochondritis dissecans / Mininder S. Kocher and Joseph J. Czarnecki -- Meniscus transplantation and cartilage resurfacing : considerations, indications, and approach / Scott A. Rodeo -- Articular cartilage repair strategies in the ankle joint / Monika Volesky, Timothy Charlton, and Jonathan T. Deland -- Management of cartilage injuries in the hip / Bryan T. Kelly, Patrick P. Sussman, and Robert L. Buly -- Rehabilitation strategies following articular cartilage surgery in the knee / John T. Cavanaugh.
    Also available: Print – 2007
  • 2014 Springer
    Jack Farr, Andreas H. Gomoll, editors.
    Attempting to bridge the gap between the science and art of cartilage restoration, Cartilage Restoration: Practical Clinical Applications combines an overview of clinical research and methodologies with clinical cases to help guide the orthopedic treatment and care of patients presenting with cartilage issues. With chapters written by internationally-renowned orthopedic surgeons, topics include an overview of current surgical options, debridement and marrow stimulation, autograft plug transfer, allografts, cell therapy, and meniscal issues. Cartilage Restoration is a valuable resource for orthopedic surgeons, residents, and fellows.
  • 2011 ClinicalKey
    Mats Brittberg, Wayne K. Gersoff.
    Cartilage Surgery: An Operative Manual by Mats Brittberg, MD and Wayne Gersoff, MD is your guide to applying the most recent advances in cartilage repair, and performing cutting-edge surgical procedures. An internationally diverse collection of authors offers a global perspective on timely topics such as cartilage biologics. Clinical pearls, operative video clips, and detailed, full-color intraoperative photographs offer step-by-step guidance on essential techniques. You can access the full content and videos online at expertconsult.com, and the videos are included on a bound-in DVD. Stay current with the recent advances in cartilage repair including surgical and non-surgical treatments as well as biologic management of cartilage lesions. Get unmatched visual guidance from an unparalleled video collection - online and on DVD - that demonstrates how to perform a variety of key techniques. Quickly reference essential topics with a templated, focused format that includes clinical pearls to help you make a confident diagnosis and select the best treatment. Benefit from the knowledge, experience, and global perspective of a diverse collection of leading international authors. Access the book from any computer at ExpertConsult.com, complete with the full text, entire image bank, and video library.
  • 2015 Springer Protocols
    edited by Pauline M. Doran.
    Cartilage tissue engineering : what have we learned in practice / Pauline M. Doran -- Human fetal and adult chondrocytes / Kifah Shahin, Nastaran Mahmoudifar, and Pauline M. Doran -- Mesenchymal stem cells derived from human bone marrow / Oliver F. W. Gardner, Mauro Alini, and Martin J. Stoddart -- Mesenchymal stem cells derived from human adipose tissue / Nastaran Mahmoudifar and Pauline M. Doran -- Derivation and chondrogenic commitment of human embryonic stem cell-derived mesenchymal progenitors / Hicham Drissi ... [et al.] -- Differentiation of human induced pluripotent stem cells to chondrocytes / Rosa M. Guzzo and Hicham Drissi -- Gene transfer and gene silencing in stem cells to promote chondrogenesis / Feng Zhang and Dong-An Wang -- Hydrogels with tunable properties / Peggy P.Y. Chan -- Decellularized extracellular matrix scaffolds for cartilage regeneration / Shraddha Thakkar, Hugo Fernandes, and Lorenzo Moroni -- Use of interim scaffolding and neotissue development to produce a scaffold-free living hyaline cartilage graft / Ting Ting Lau ... [et al.] -- Bioprinted scaffolds for cartilage tissue engineering / Hyun-Wook Kang, James J. Yoo, and Anthony Atala -- Scaffolds for controlled release of cartilage growth factors / Marie Morille ... [et al.] -- Nanostructured capsules for cartilage tissue engineering / Clara R. Correia, Rui L. Reis, and João F. Mano -- Stratified scaffolds for osteochondral tissue engineering / Patcharakamon Nooeaid, Gundula Schulze-Tanzil, and Aldo R. Boccaccini -- Mechanobioreactors for cartilage tissue engineering / Joanna F. Weber, Roman Perez, and Stephen D. Waldman -- Shear and compression bioreactor for cartilage synthesis / Kifah Shahin and Pauline M. Doran -- Microbioreactors for cartilage tissue engineering / Yu-Han Chang and Min-Hsien Wu -- Transplantation of tissue-engineered cartilage in an animal model (xenograft and autograft) : construct validation / Hitoshi Nemoto, Deborah Watson, and Koichi Masuda -- Proteomic analysis of engineered cartilage / Xinzhu Pu and Julia Thom Oxford -- Mechanical testing of cartilage constructs / Dinorath Olvera, Andrew Daly, and Daniel John Kelly.
  • 2008
    editor, Curtis D. Klaassen.
    Status: Not Checked OutLane Catalog Record
    Unit I: General principles of toxicology -- History and scope of toxicology / Michael A. Gallo -- Principles of toxicology / David L. Eaton and Steven G. Gilbert -- Mechanisms of toxicity / Zoltán Gregus -- Risk assessment / Elaine M. Faustman and Gilbert S. Omenn -- Unit II: Disposition of toxicants -- Absorption, Distribution, and excretion of toxicants / Lois D. Lehman-McKeeman -- Biotransformation of xenobiotics / Andrew Parkinson and Brian W. Ogilvie -- Toxicokinetics / Danny D. Shen -- Unit III: Non-organ-directed toxicity -- Chemical carcinogens / James E. Klaunig and Lisa M. Kamendulis -- Genetic toxicology / R. Julian Preston and George R. Hoffmann -- Developmental toxicology / John M. Rogers and Robert J. Kavlock -- Unit IV: Target organ toxicity -- Toxic responses of the blood / John C. Bloom and John T. Brandt -- Toxic responses of the immune system / Norbert E. Kaminski ... [et al.] -- Toxic responses of the liver / Hartmut Jaeschke -- Toxic responses of the kidney / Rick G. Schnellmann -- Toxic responses of the respiratory system / Hanspeter R. Witschi ... [et al.] -- Toxic responses of the nervous system / Virginia C. Moser ... [et al.] -- Toxic responses of the ocular and visual system / Donald A. Fox and William K. Boyes -- Toxic responses of the heart and vascular system / Y. James Kang -- Toxic responses of the skin / Robert H. Rice and Theodora M. Mauro -- Toxic responses of the reproductive system / Paul M.D. Foster and L. Earl Gray Jr. -- Toxic responses of the endocrine system / Charles C. Capen -- Unit V: Toxic agents -- Toxic effects of pesticides / Lucio G. Costa -- Toxic effects of metals / Jie Liu, Robert A. Goyer, and Michael P. Waalkes -- Toxic effects of solvents and vapors / James V. Bruckner, S. Satheesh Anand, and D. Alan Warren -- Health effects of radiation and radioactive materials / Naomi H. Harley -- Properties and toxicities of animal venoms / John B. Watkins, III -- Toxic effects of plants / Stata Norton -- Unit VI: Environmental toxicology -- Air pollution / Daniel L. Costa -- Ecotoxicology / Richard T. Di Giulio and Michael C. Newman -- Unit VII: Applications of toxicology -- Food toxicology / Frank N. Kotsonis and George A. Burdock -- Analytic/forensic toxicology / Alphonse Poklis -- Clinical toxicology / Louis R. Cantilena Jr. -- Occupational toxicology / Peter S. Thorne.
  • 2015 Springer
    [edited by] Catherine Marcucci, Michael P. Hutchens, Erica D. Wittwer, Toby N. Weingarten, Juraj Sprung, Wayne T. Nicholson, Kirk Lalwani, David G. Metro, Randal O. Dull, Christopher E. Swide, F. Jacob Seagull, Jeffrey R. Kirsch, Neil B. Sandson.
  • 2010
    Pearl S. Berman.
    Status: Not Checked OutLane Catalog Record
    Developing case conceptualizations and treatment plans -- The complexity of human experience -- Behavioral case conceptualizations and treatment plans -- Cognitive case conceptualizations and treatment plans -- Feminist case conceptualizations and treatment plans -- Emotion-focused case conceptualizations and treatment plans -- Dynamic case conceptualizations and treatment plans -- Family systems case conceptualizations and treatment plans -- Constructivist case conceptualizations and treatment plans -- Transtheoretical case conceptualizations and treatment plans -- Discussion and extension of the model.
  • 2014
    Eugene C. Toy, Manuel Suarez, Terrence H. Liu.
    Status: Not Checked OutLane Catalog Record
    "Experience with clinical cases is key to mastering the art and science of medicine and ultimately to providing patients with compotent clinical care. [This book] provides 42 true-to-life cases that illustrate essential concepts in critical care. Each case includes an easy-to-understand discussion correlated to key concepts, definitions of key terms, clinical pearls, and board-style review questions to reinforce your learning."
  • 2013 AccessEmergency Medicine
    Eugene C. Toy, Barry C. Simon, Katrin Y. Takenaka, Terrence H. Liu, Adam J. Rosh.
    "Real life cases for the emergency medicine clerkship and shelf-exam. Case Files: Emergency Medicine presents 50 real-life cases that illustrate essential concepts in emergency medicine. Each case includes a complete discussion, clinical pearls, references, definitions of key terms, and USMLE-style review questions. With this system, you'll learn in the context of real patients, rather then merely memorize facts. 60 high-yield emergency medicine cases, each with USMLE-style questions Clinical pearls highlight key concepts Primer on how to approach clinical problems and think like a doctor Proven learning system maximizes your shelf-exam scores"--Provided by publisher.
  • 2008
    Eugene C. Toy, Ericka Simpson, Milvia Pleitez, David Rosenfield, Ron Tintner
    Status: Not Checked OutLane Catalog Record
  • 2009
    [edited by] Eugene C. Toy, Benton Baker III, Patti Jayne Ross, John C. Jennings.
    Status: Not Checked OutLane Catalog Record
  • 2013 AccessSurgery
    Eugene C. Toy, Terrence H. Liu, Andre R. Campbell.
    "You need exposure to high-yield cases to excel in the surgery clerkship and on the shelf exam. Case files: surgery presents 56 real-life cases that illustrate essential concepts in surgery. Each case includes a complete discussion, clinical pearls, references, definitions of key terms, and USMLE-style review questions. With this system, you'll learn in the context of real patients, rather then merely memorize facts."--Publisher's website.
  • Consentino, Marc P.
    Status: Not Checked OutLane Catalog Record
  • 2011 ClinicalKey
    Thierry A.G.M. Huisman ... [et al.].
    Pediatric Imaging: Case Review, by Thierry A.G.M. Huisman, MD, tests your ability to interpret a wide range of images seen in practice. The completely revised edition of this title in the popular Case Review series features all-new cases and superb-quality accompanying images that explore the newest imaging modalities, including the newest technology in post processing such as lung reconstruction and tractography of fibers within the brain. This complete study of pediatric imaging has been reorganized anatomically for quick reference and easy board review. This book contains approximately 200 cases-organized by difficulty-and 400 images-with questions and answers, diagnoses, commentary, references, and cross-references to Pediatric Radiology: The Requisites. Study effectively with content that mimics the format of official exams as well as the everyday clinical experience-offering highly effective preparation for certification, recertification, and practice. Distinguish between common and rare diagnoses with 200 case studies organized into ''Opening Round, '' ''Fair Game, '' and ''Challenge'' sections that present varying levels of difficulty and occurrences. Clearly see and interpret 400 high-quality, state-of-the-art images representing a wide range of clinical situations encountered in pediatric imaging. Supplement your Pediatrics board prep and get greater depth of information with easy cross-referencing to companion.
  • 2012 ClinicalKey
    Neil J. Friedman, Peter K. Kaiser.
    Optics/Refraction -- Neuro-Ophthalmology/Orbit -- Pediatric Ophthalmology/Strabismus -- External Disease/Adnexa -- Anterior segment -- Posterior segment -- Index of Cases.
  • William Ellet.
    Status: Not Checked OutLane Catalog Record
  • 2011 Springer
    Rita Joarder, Neil Crundwell, Matthew Gibson.
  • 2015 Cambridge
    [edited by] Nick S. Macklon, University of Southampton, UK, Human M. Fatemi, the Centre for Reproductive Medicine, NOVA-IVI Fertility, Abu Dhabi/UAE, Robert J. Norman, the University of Adelaide, Australia, Pasquale Patrizio, Yale School of Medicine, New Haven, CT, USA.
    1. Type 2 diabetes mellitus -- 2. A woman with hypertension -- 3. Increased risk of venous thromboembolism (VTE) -- 4. Assisted reproduction in a subfertile couple with serodiscordant HIV infection -- 5. A woman with renal impairment -- 6. A male with oligozoospermia and muscle weakness subsequently diagnosed with myotonic dystrophy -- 7. Never say never to a Klinefelter patient -- 8. A man with retrograde ejaculation -- 9. A patient with severe lupus -- 10. One partner is a carrier of thalassemia, one a carrier of sickle cell anemia -- 11. A patient with Kallmann syndrome -- 12. A patient with severe endometriosis needing IVF -- 13. Recurrent miscarriage due to a balanced translocation -- 14. A patient found to have Cushing syndrome -- 15. Postpartum pituitary problems -- 16. Large bilateral endometriomas -- 17. A patient with a thin endometrium -- 18. A poor responder -- 19. Recurrent implantation failure -- 20. Fertility preservation in an adolescent with Turner syndrome -- 21. A young woman with a low AMH -- 22. The patient who bleeds in the early luteal phase -- 23. Threatened OHSS in a long GnRH agonist protocol -- 24. An endometrial polyp detected during ovarian stimulation for IVF -- 25. Fluid in the endometrial cavity during IVF treatment -- 26. Tubal embryo transfer -- 27. Mild-approach ART in a patient with polycystic ovary syndrome -- 28. A slim patient with polycystic ovary syndrome (PCOS) -- 29. Recurrent cycles with retrieval of immature germinal vesicle (GV) oocytes -- 30. Think heterotopic pregnancy -- 31. A woman with a hydrosalpinx -- 32. A PCOS patient with microprolactinoma, autoimmune thyroid disease, and congenital thrombophilia -- 33. IVF outcome in the same patient before and after myomectomy -- 34. A patient with factor XI deficiency and immune thrombocytopenia -- 35. Abnormal cavity; abnormal fertility? -- 36. A male partner with 'flu -- 37. Selecting the day of triggering final oocyte maturation when follicle growth is asynchronous -- 38. Late-onset ovarian hyperstimulation syndrome (OHSS) -- 39. The patient with recurrent poor embryo quality -- 40. A high progesterone level during ovarian stimulation -- 41. Repeated fertilization failure with normal sperm and MII oocytes -- 42. A complete uterine septum -- 43. Endometritis detected prior to IVF -- 44. LH rise on the day of GnRH antagonist commencement -- 45. Controlled ovarian stimulation (COS) in a woman with normal ovarian reserve -- 46. Errors in dosing medications -- 47. Monozygotic triplets after single embryo transfer -- 48. A teenager facing total body irradiation -- 49. A 30-year-old woman with breast cancer -- 50. A spontaneous pregnancy in Turner syndrome -- 51. Fertility after conservative surgery for recurrent borderline ovarian tumor -- 52. Successful pregnancy after radical trachelectomy and McDonald cerclage placement in a 42-year-old with invasive cervical adenocarcinoma -- 53. Childbearing after conservative management of endometrial cancer -- 54. Fertility preservation in a female of reproductive age with ovarian cancer -- 55. Mother daughter triplet surrogacy: the first reported case -- 56. Known sperm donation -- 57. A 5-year-old with pelvic rhabdomyosarcoma -- 58. Co-fatherhood -- 59. Sensorineural hearing loss following ovarian stimulation.
  • 2012 Springer
    Rita Joarder, Neil Crundwell.
  • 2010
    edited by Rebecca Jeanmonod, Michelle Tomassi, Dan Mayer.
    Status: Not Checked OutLane Catalog Record
    "A case-based book organized by the top 10 common complaints of patients presenting to emergency departments. This approach allows the reader to learn the pathophysiology of the major diseases, and analyze each case in a way that more closely approximates the clinical practice of medicine; not knowing which organ system is damaged or compromised before examining the patient. The cases are based on real patients and the diseases are either common in emergency practice, or are dangerous diagnoses not to be missed. The case descriptions include questions regarding the patient's presentation and basic information about the disease, illustrating key elements from the history, physical, and when necessary ancillary studies that help lead to a diagnosis. Each chapter ends with a flow diagram showing how diseases of different organ systems can present with similar initial complaints. This book is an ideal resource for medical students, residents and trainees in emergency medicine"--Provided by publisher.
  • 2012 Cambridge
    [edited by] Hermann Stefan, Elinor Ben-Menachem, Patrick Chauvel, Renzo Guerrini.
    1. First seizure: is it epilepsy? -- 2. Intractable epilepsy and epilepsia partialis continua associated with respiratory chain deficiency -- 3. Reasons for violent behaviour, when a man strangles his wife -- 4. Repetitive monocular eye adduction -- 5. Febrile infectious-related epilepsy syndrome (FIRES) -- 6. Epileptic seizures as presenting symptom of the Shaken Baby Syndrome -- 7. Benign rolandic epilepsy -- 8. New onset focal and generalized epilepsy in an elderly patient -- 9. When laughing makes the child fall down -- 10. Epileptic spasms and abnormal neuronal migration -- 11. A feeling of gooseflesh -- 12. Generalized epilepsy in adolescence as initial manifestation of Lafora disease -- 13. Epilepsy with a right temporal hyperintense lesion in MRI -- 14. Epileptic falling seizures associated with seizure-induced cardiac asystole in drug-resistant temporal lobe epilepsy -- 15. Seizures, dementia and stroke? -- 16. Comorbidity in epilepsy, dual pathology resulting in simple focal, complex focal and tonic clonic seizures -- 17. Minor motor events -- 18. Epilepsy in the ring chromosome 20 -- 19. A late diagnosis of mesial temporal lobe epilepsy -- 20. Experiental phenomena in temporal lobe epilepsy -- 21. The use of depth EEG (SEEG) recordings in a case of frontal lobe epilepsy -- 22. A frontal lobe epilepsy surgery based on totally non-invasive investigations -- 23. A young man with reading-induced seizure -- 24. The lady from 'no-man's-land' -- 25. The man who came (too) late -- 26. Paraneoplastic limbic encephalitis -- 27. Really a cerebrovascular story? -- 28. Sudden unexpected death in epilepsy, the ultimate failure -- 29. Blind but able to see -- 30. Seizure disorder! Really unexpected? -- 31. Transient epileptic amnesia in late onset epilepsy -- 32. A really unexpected injury? -- 33. Epileptic negative myoclonus in benign rolandic epilepsy -- 34. Sporadic hemiplegic migraine -- 35. A strange symptom: psychotic or ictal? -- 36. Hearing voices: focal epilepsy guides diagnosis of genetic disease -- 37. Life threatening status epilepticus due to focal cortical dysplasia -- 38. Childhood occipital idiopathic epilepsy -- 39. Unconscious: never again work above a meter? -- 40. A patient's patience -- 41. Idiopathic absence epilepsy: unusual AED consumption successful -- 42. Woman with gastric reflux, careful with combinations of medications -- 43. An example of both pharmacodynamic and pharmacokinetic interactions -- 44. Never give up trying to find the right medication even in patients who are refractory -- 45. Juvenile myoclonic epilepsy and seizure aggravation -- 46. Episodic aphasia, surgery or not? -- 47. Temporal lobe epilepsy: drugs or surgery? -- 48. Shaking in elderly: reversible or fate? -- 49. Failure of surgical treatment in a typical medial temporal lobe epilepsy -- 50. Cutaneous adverse reactions by AEDs: chance or predetermination? -- 51. Timing of medical and surgical treatment of epilepsy: a hemispherotomy that would have prevented disabling cerebellar atrophy -- 52. Anticonvulsive drugs for gate disturbance and slurred speech? -- 53. Unsuccessful surgery: another chance? -- 54. If it's not broken, don't fix it! -- 55. Never ever give up -- 56. Hippocampal deep brain stimulation may be an alternative for resective surgery in medically refractory temporal lobe epilepsy -- 57. Myoclonic seizures and recurrent nonconvulsive status epilepticus in Dravet syndrome -- 58. Functional hemispherotomy for drug-resistant post-traumatic epilepsy -- 59. Pharmoresistent epilepsy? -- 60. Vagus nerve stimulation for epilepsy -- 61. The strange behaviour of a vegetarian: a diagnostic indicator for treatment? (a quiz case) -- Index.
  • 2007 Springer
    Sana Loue, Earl C. Pike.
  • 2009 Springer
    Cheryl Vince Whitman, Carmen E. Aldinger, editors.
  • 2012
    Raif Geha, Luigi Notarangelo.
  • c2012
    Raif S. Geha & Luigi Notarangelo
    Status: Not Checked OutLane Catalog Record
  • 2008
    Raif Geha, Fred Rosen.
    Status: Not Checked OutLane Catalog Record
  • 2012 Cambridge
    Claudia Sommer, Douglas Zochodne.
    "Among all patients with neurological disorders, pain is probably the most common symptom experienced. Identifying, understanding and treating pain is a responsibility of health care providers in all branches of neurology. This text is about pain in neurological diseases, both 'neuropathic' pain that is recognized in sensory neuron disorders but also other types of pain less commonly considered. These latter disorders include for example, pain in Parkinson's disease, ALS and muscle diseases. The text includes specific chapters on mechanisms of neuropathic pain, updated with new ideas on its pathogenesis, and a summary of recent therapeutic guidelines. Most of the text however centers on actual patient encounters at the Neurology clinics of the Universities of Wurzburg and Calgary. This emphasis is to make the vignettes relevant to clinical practitioners but also to introduce researchers and workers in industry to the complex and challenging issues faced during direct patient encounters. Therapeutic failures are common among our vignettes, highlighting the fact that current therapeutic advances remain inadequate-a challenge for researchers to find better approaches"--Provided by publisher.
  • 2015 Cambridge
    edited by Alan David Kaye, MD, PhD, DABA, DABPM, DABIPP, Professor and Chairman, Department of Anesthesiology, Director of Interventional Pain Services, LSU School of Medicine, New Orleans, LA, USA, Rinoo V. Shah, MD, MBA, DABPMR, DABIPP, Interventional Pain Physician and Minimally Invasive Spine Specialist at Guthrie Clinic, Sayre, PA, USA.
    Section 1. Neurological disorders -- Section 2. Spinal disorders -- Section 3. Musculoskeletal pain -- Section 4. Visceral pain -- Section 5. Headaches and facial pain -- Section 6. Cancer pain -- Section 7. Special topics.
  • 2012 Wiley
    edited by Margaret L. Campbell.
    "Case Studies in Palliative and End-of-Life Care uses a case-based approach to provide students and practitioners with an important learning tool to improve critical thinking skills and encourage discussion toward improving experiences for patients and their families. The book is organized into three sections covering subjects related to communication, symptom management, and family care. Each case is presented in a consistent, logical format for ease of use, highlighting key evidence-based concepts including the case history, care setting, diagnosis and prognosis, assessment, treatment considerations, and family support. A key reference, Case Studies in Palliative and End-of-Life Care is an invaluable resource for clinicians who provide palliative care to patients with life-limiting illnesses and those at the end of life along with their families."--Publisher's description.
  • 2010 CRCnetBASE
    Lynne Berdanier, Carolyn D. Berdanier.
    "Today's knowledge of human health demands a multidisciplinary understanding of medically related sciences, and Case Studies in the Physiology of Nutrition answers the call. Dedicated to the integration of nutrition science with physiology, this text cohesively incorporates descriptions of human problems in order to stimulate students' critical thinking about how the body integrates various physiological factors to maintain homeostasis. This textbook uses short story-type case studies about fictional individuals who have health problems in order to address a range of issues in an approachable manner. The studies vary in difficulty, with some being straightforward with very simple answers, while others require in-depth thinking and literature research to solve. Each study presents patient background, symptoms, clinical finding, and questions to ponder. Upon qualifying course adoption, this book also includes a valuable instructor's manual, which provides solutions to exercises, problem analysis, and resolution to each case study."--Publisher's description.
  • 2011 Springer
    Richard M. Silver, Christopher P. Denton, editors.
  • 2011 Springer
    John G. Brock-Utne.
    Case 1: A Patient with a Mediastinal Mass -- Case 2: Stick Out Your Tongue -- Case 3: An Epidural Blood Patch - What Went Wrong? -- Case 4: A Lack of Communication Leads to a Bad Outcome -- Case 5: Hyperkalemia During Coronary Artery Bypass Graft -- Case 6: An Adjuvant to the Cuff-Leak Test -- Case 7: Acinetobacter baumannii Outbreak in an ICU - Can Our Equipment Be at Fault? -- Case 8: A Complication with the Use of the Intubating Fiberscope -- Case 9: Interscalene Block a Concern in Cardiac Patients? -- Case 10: Epidural Analgesia for Labor - Watch Out -- Case 11: Past History of Esophagectomy - Any Concern? -- Case 12: A Case of Myasthenia Gravis -- Case 13: Where Are My Teeth? -- Case 14: An Unusual Capnograph Tracing -- Case 15: A VP Shunt -- Case 16: Shoulder Surgery - Watch Out! -- Case 17: An Ambulatory Surgical Patient with No Escort -- Case 18: A Complication During Laparoscopy -- Case 19: A Patient with Amyotrophic Lateral Sclerosis.
  • 2014 Springer
    Miguel A. Cuesta, H. Jaap Bonjer, editors.
    1. Suspicion of an Anastomotic Problem after Esophageal Resection for Cancer -- 2. Cervical Leakage of an Oesophago-Gastric Conduit Anastomosis -- 3. Thoracic Duct Injury -- 4. Postoperative Hiatal Herniation after Esophageal Resection -- 5. Benign Stenosis of the Intrathoracic and Cervical Esophagogastric Anastomosis after Esophagectomy -- 6. Recurrent Nerve Lesion (Double) As a Consequence of Esophageal Resection for Cancer -- 7. Trachea-Gastric Conduit Fistula after Esophageal Resection -- 8. Herniation of the Stomach into the Thorax after Laparoscopic Repair of a Type 3 Para-Esophageal Hernia -- 9. Dysphagia after Laparoscopic Nissen Fundoplication -- 10. Iatrogenic Esophageal Perforation -- 11. Peritonitis after Unrecognized Perforation Following Heller Myotomy and Dor Fundoplication for Achalasia -- 12. Esophagojejunostomy Leakage Following Extended Total Gastrectomy -- 13 -- Leakage of the Duodenal Stump Following Gastrectomy -- 14.Re-Bleeding after Repair of Bleeding Duodenal Ulcer -- 15. Stenosis of a Side-To-Side Gastrojejunostomy after a Laparoscopic Subtotal Gastrectomy -- 17. Leakage after Closure of a Perforated Duodenal Diverticulum -- 18. An Acute Complication of the Wilki Syndrome -- 19. Distal Duodenal Perforation after Double Balloon Endoscopy (DBE) -- 20.Duodenal Leakage after Resection of an Insulinoma of the Head of the Pancreas -- 21. Postoperative Intraluminal Bleeding Following a Gastric Bypass -- 22. Complication of Sleeve Gastrectomy after Bariatric Surgery -- 23. Leakage of Gastric Bypass Performed Because Of Obesity -- 24. Complication of Adjustable Gastric Band Converted in a Gastric Bypass -- 25. Problems with Laparoscopic Adjustable gastric band: erosion and migration -- 26. Jaundice and Hepatic Failure after Major Hepatic Resection -- 27. Biliary Leakage and Abscess after Liver Resection -- 28. A Patient with Biliary Strictures in One Half of the Liver after Liver Transplantation -- 29. Patient with a Stenosis of the Cavocavostomy after Liver Transplantation -- 30. CBD Lesion during Laparoscopic Cholecystectomy -- 31. CBD Lesion during Laparoscopic Cholecystectomy -- 32. Hepatic Abscess after Double Lesion (CBD and Right Hepatic Artery) During Cholecystectomy -- 33. Unrecognized CBD Stones after Laparoscopic Cholecystectomy -- 34. Recurrence of Gallbladder Acute Pancreatitis: When to Perform a Cholecystectomy? -- 35. Complicated Retained Stones in the Common Bile Duct after Multiple Sphincterotomies by ERCP -- 36. Complications after ERCP and Sphincterotomy -- 37. Lost Stones in Abdomen after Laparoscopic Cholecystectomy -- 38. Late Stenosis of Bilio-Digestive Anastomosis with Cholangitis (After Laparoscopic Cholecystectomy) -- 39. Complication after Surgical Treatment Klatskin Tumor -- 40. Postoperative Intraluminal Bleeding after Whipple Resection -- 41. Leakage of the Pancreato-Jejunostomy after a Whipple Procedure -- 42. Bile Leakage (And Portal Vein Thrombosis) after Whipple Procedure -- 43. Bleeding in the Small Remnant of the Head of the Pancreas after Duodenum Preserving Resection for Middle Pancreatic Tumor -- 44. Impaction of Enteral (Bezoars) During Enteral Feeding After Whipple Procedure -- 45. Gastric Bleeding Caused by a Necrotizing Pancreatitis with Extensive Pseudocyst Formation -- 46. 'Infection Is Not Found but Patient Is Becoming Worse' -- 47. Pseudocyst Pancreas, Endoscopically or Surgical Treatment? -- 48. Pancreatic Pseudocyst Far from the Stomach -- 49. Intra-Abdominal Bleeding with Shock as Consequence of Necrotizing Pancreatitis -- 50. Recurrence of Infection after Video-Assisted Retroperitoneal Debridement -- 51. Splenic and Portal Vein Thrombosis after Splenectomy -- 52. Rebleeding after Initial Coiling Of Spleen Trauma -- 53. Adrenal Insufficiency (Addison Syndrome), After Removal of an Adenocarcinoma of the Adrenal Gland -- 54. Leakage after Left Pancreatic Resection -- 55. Postoperative Shock during Laparoscopic Appendicectomy -- 56. Postoperative Abscess After Appendicectom -- 57. Carcinoid Discovered in the Appendix -- 58. Complications after Conservatively Treated Appendicular Phlegmon -- 59. Anastomotic Leakage Following Small Bowel Resection -- 60. Recurrence of Crohn's Disease -- 61. Short Bowel Syndrome -- 62. Recurrence of Intestinal Obstruction Because of Adhesions -- 63. Inadvertent Small Bowel Lesion during Laparoscopic Operation -- 64.Small Bowel Ischemia during Neoadjuvant Chemotherapy Because of Gastro- Esophageal Junction Cancer -- 65. Complications of Malrotation -- 66. Leakage after Right Hemicolectomy -- 67. Anastomotic Rotation after Laparoscopic Right Hemicolectomy for Colonic Cancer -- 68. Leakage after Elective Ileo-Cecal Resection for Crohn's Disease -- 69. Leakage after Ileoanal Pouch Anastomosis, IAPA -- 70. Leakage after Sigmoid Resection -- 71. Leakage after LAR and Coloanal Anastomosis -- 72. Presacral Abscess and Sinuses after Lar -- 73. Stenosis after LAR -- 74. Problems after Coloanal Anastomosis (Stenosis Coloanal Anastomosis and Repeated Stools and Soiling) -- 75. Ureter Lesion during Low Anterior Resection -- 76. Late Ileo-Anal Pouch Anastomosis Fisteling (Vaginal And Perineal) -- 77. Ano-Rectal Adenocarcinoma in a Colorectal Crohn's Disease -- 78. Recto-Vaginal Fistula after LAR -- 79. Recto-Vesical Fistula after LAR -- 80. Perianal Problems after APR -- 81. Recurrence after TME Because of Rectal Cancer -- 82. Complication after Laparoscopic Abdominal Lavage Because of Perforated Diverticuliti -- 83. Anastomotic Leakage After Taken Down Hartmann Procedure -- 84. Complication after Sacrocolpopexy -- 85. Ischemia-Necrosis of the Sigmoid After Repair of A Ruptured Juxta-Renal Aneurysm -- 86. Complications and Approach in Post-Radiation Enteritis -- 87. Complications Following Cytoreductive Surgery and Heated Intraperitoneal Chemotherapy (HIPEC) -- 88. Colorectal Anastomosis Bleeding -- 89. Laparoscopic Approach of Anastomotic Leakage after Laparoscopic Resection -- 90. Leakage Distal Anastomosis after Low Anterior Resection with Protective Ileostomy -- 91. Leakage Distal Anastomosis After Low Anterior Resection (Lar) Without Protective Ileostomy -- 92. Complications of Ileostomy -- 93. Necrosis of Colostomy. Retraction and Stenosis -- 94. Parastomal Hernia Complications -- 95. Severe Complication after Pph Procedure for Hemorrhoids -- 96. Complex Recurrent Anal Fistula -- 97. Faecal Incontinence after Delivery -- 98. Rectovaginal Fistula Following Delivery -- 99. Dehiscence/Evisceration of the Abdominal Wall after Laparotomy -- 100. Recurrence of Open Incisional Hernia after Large Hernia Repair Using (Low-Weight) Polypropylene Mesh -- 101. Abdominal Compartment Syndrome -- 102. Enterocutaneous Fistula Through Previous Laparotomy -- 103.Care and Closure of Open Abdomen Approach.
  • 2012 Cambridge
    edited by Victor H. Gerbaudo.
    A Case-Based Approach to PET/CT in Oncology describes the role of PET/CT in the diagnosis, staging and monitoring of treatment response in today's practice of oncology. It provides a detailed analysis of over 100 cases occurring in daily clinical practice, emphasizing the central role that PET imaging plays in the care of cancer patients. The text is organized into two sections; Part I guides the reader through general introductory concepts, including basic science, while Part II covers in-depth oncologic applications. Each case is illustrated throughout with full color images and explains the key management issues and the advantages and limitations of the modality. Written by a team of renowned international experts, A Case-Based Approach to PET/CT in Oncology is an invaluable resource for all imaging practitioners, oncologists and nuclear medicine specialists.
  • 2013 Thieme Book
    [edited by] A. John Tsiouris, Pina C. Sanelli, Joseph P. Comunale.
  • 2015 Springer
    edited Aksel Siva, Christian Lampl, editors.
    This book provides the practicing physician with a practical approach to the diagnosis, evaluation, and management of headache disorders based on lessons learned from real-life headache patients. Internationally well-known headache experts present cases from their own practice and discuss the evaluation and management of each case step by step. The clearly structured chapters cover initial evaluation and diagnostic work-up, imaging, differential diagnosis, interpretation of findings of further work-up, treatment options and response and key points. A wide spectrum of headache types is covered, including both primary and secondary headache disorders. The reader will learn how to diagnose and manage different headache disorders directly from the clinical experience of experts. Case-Based Diagnosis and Management of Headache Disorders will be of value for neurologists and a wide range of physicians - from those in other specialties to primary care givers.
  • 2011 Springer
    edited by Theodore Abraham.
    Physics and Artifacts -- Basic Ultrasound Views -- Quantification of Left Ventricular Size and Wall Thickness -- Quantification of Left Ventricular Systolic Function -- Noninvasive Hemodynamic Assessment -- Echocardiographic Assessment of Diastolic Dysfunction (DD) and Heart Failure with Normal EF (HFnlEF) -- Tissue Doppler Imaging and Strain Echocardiography -- Transesophageal Echocardiography -- Intraoperative Transesophageal Echocardiography -- Use of Echo Contrast in Routine Practice -- Three-Dimensional Echocardiography -- Stress Echocardiography --Mechanical Dyssynchrony Assessment -- Post Cardiac Resynchronization Therapy (CRT) Optimization Protocol -- Echocardiographic Assessment of the Right Ventricle -- Aortic Valve Stenosis and Regurgitation -- Mitral Prolapse Regurgitation and Mitral Stenosis -- Right-Sided Heart Valves Assessment in Disease -- The Assessment of Prosthetic Valve Function -- The Aorta: Diseases of the Aorta -- Hypertrophic Cardiomyopathy -- Stress Cardiomyopathy -- Pericardial Diseases -- Atrial Septal Defect -- Percutaneous Interventions for Congenital Heart Defects -- Cardiac Tumors and Masses -- Cardiac Transplantation -- Vascular Imaging.
  • 2015 Springer
    Terry F. Davies, editor.
    1: Pituitary -- Overview: The role of medical therapy for secretory pituitary adenomas: current practices and new therapeutics -- Acromegaly, awareness is paramount for early diagnosis: highlights of diagnosis and treatment challenges -- A non-traumatic hip fracture in a young woman: Cushing's disease -- consequences of a late diagnosis and treatment highlights -- Section 2: Thyroid overactivity.- Introduction.- TSH-Secreting Pituitary.- Struma Ovarii.- Exogenous Thyrotoxicosis -- Section 3: Thyroid underactivity.- Thyroid Underactivity: Introduction.- Central Hypothyroidism.- Treatment of hypothyroidism -- Utility of adding T3 (liothyronine).- Hypothyroidism in Pregnancy -- Hypothyroid myopathy and thelogen effluvium -- Section 4: Thyroid cancer.- Introduction on Thyroid Chapters.- Approach to the Patient with an Incidentally Discovered Thyroid Nodule.- Papillary Thyroid Cancer.- Metastatic papillary thyroid cancer.- Management of Metastatic Medullary Thyroid Cancer.- Thyroid cancer and bone metastases -- Section 5: Adrenal.- Primary aldosteronism.- Adrenal Incidentaloma and Subclinical Hypercortisolism.- A Case of Pheochromocytoma -- Section 6: Hyperparathyroidism.- Introduction: Parathyroid Disorders -- Complex hyperparathyroidism.- Differential diagnosis of hypocalcemia.- Management of hypoparathyroidism.- Osteomalacia and primary hyperparathyroidism -- Section 7: Metabolic bone diseases -- Advances and challenges in the management of Osteoporosis.- Multiple Risk Factors for Osteoporosis and Fracture.- Delayed Diagnosis of Osteoporosis.- Misdiagnosis of atypical Femur Fractures -- Section 8: Endocrine Disorders of Men.- Introduction: Endocrine Disorders in Men.- Congenital Hypogonadotropic Hypogonadism.- Klinefelter Syndrome.- Low testosterone and the Metabolic Syndrome -- Section 9: Pregnancy.- Introduction: Endocrine Cases and Pregnancy.- Getting pregnant with PCOS.- Thyrotoxicosis in pregnancy.- Gestational diabetes -- Section 10: Diabetes.- Introduction: Type 2 Diabetes.- Evaluation and Management of the Newly-diagnosed Patient with Type 2 Diabetes.- Transition to Insulin in Patients with Type 2 Diabetes.- Inpatient management -- Section 11: Lipid abnormalities.- Introduction: On Lipids.- LDL-apheresis Therapy for Refractory Familial Hypercholesterolemia.- Familial type II Hyperlipoproteinemia (familial dysbetalipoproteinemia).- Severe hypertriglycideremia -- Section 12: Obesity.- Introduction -- Obesity and the metabolic syndrome.- Managing a metabolic syndrome case.- The Polycystic Ovarian Syndrome (PCOS).- Bariatric Surgery.
  • 2008 Springer
    Terry F. Davies, editor.
  • 2016 Springer
    Marcia Hogeling, editor.
  • 2011 Thieme Book
    Timo Krings, Sasikhan Geibprasert, Karel G. ter Brugge.
    PART I. Aneurysms and Subarachnoid Hemorrhage -- CASE 1. Embolization of a Ruptured Basilar Tip Aneurysm -- CASE 2. Embolization of a Ruptured Anterior Communicating Artery Aneurysm -- CASE 3. Multiple Aneurysms in a Patient with Subarachnoid Hemorrhage -- CASE 4. Management of an Unruptured Internal Carotid Artery Aneurysm -- CASE 5. Balloon-Assisted Embolization of a Ruptured Wide-Necked Anterior Communicating Artery Aneurysm -- CASE 6. Stent-Assisted Embolization of a Wide-Necked Recurrent Posterior Communicating Artery Aneurysm -- CASE 7. Management of Complications during Aneurysm Coiling: Proximal Mechanically Induced Vasospasm -- CASE 8. Management of Complications during Aneurysm Coiling: Periprocedural Aneurysm Rupture -- CASE 9. Management of Complications during Aneurysm Coiling: Periprocedural Thrombus Formation -- CASE 10. Management of Subarachnoid Hemorrhage-Induced Vasospasm -- CASE 11. Management of Giant “Partially Thrombosed” Aneurysms -- CASE 12. Embolization of a Dissecting Vertebral Artery Aneurysm -- CASE 13. Embolization of a Dissecting Distal Anterior Inferior Cerebellar Artery Aneurysm -- CASE 14. Embolization of an Infectious Distal Middle Cerebral Artery Aneurysm -- PART II. Brain Arteriovenous Malformations -- CASE 15. Arterial Embolization of an Unruptured Pial Arteriovenous Malformation -- CASE 16. Partial Targeted Embolization of an Unruptured Pial Arteriovenous Malformation -- CASE 17. Pre-radiosurgical Embolization of an Unruptured Pial Arteriovenous Malformation -- CASE 18. Embolization of an Acutely Ruptured Arteriovenous Malformation with Intranidal Aneurysm -- CASE 19. Management of Hydrocephalus in an Unruptured Pial Arteriovenous Malformation -- CASE 20. Embolization of a Pial Fistulous Arteriovenous Malformation -- CASE 21. Partial Embolization of a Choroidal Fistulous Arteriovenous Malformation -- CASE 22. Embolization of a Microshunt into a Developmental Venous Anomaly -- PART III. Cranial Dural Arteriovenous Shunts -- CASE 23. Arterial Embolization of a Lateral Epidural Type of Dural Arteriovenous Fistula -- CASE 24. Arterial Embolization of an Ethmoidal Dural Arteriovenous Fistula -- CASE 25. Transarterial Embolization of a Transverse Sinus Dural Arteriovenous Fistula -- CASE 26. Transvenous Embolization of a Transverse Sinus Dural Arteriovenous Fistula -- CASE 27. Transvenous Embolization through Thrombosed Dural Sinus of an Aggressive Transverse Sinus Dural Arteriovenous Fistula at the Level of an Isolated Dural Sinus -- CASE 28. Transvenous Embolization of a Condylar Confluence Dural Arteriovenous Fistula -- CASE 29. Transvenous Embolization of a Cavernous Sinus Dural Arteriovenous Fistula -- CASE 30. Multiple Dural Arteriovenous Fistulae -- PART IV. Head and Neck Vascular Lesions -- CASE 31. Transarterial Embolization of a Mandibular Arteriovenous Fistula -- CASE 32. Combined Direct Puncture and Transarterial Embolization of a Scalp Arteriovenous Malformation -- CASE 33. Percutaneous Puncture of a Facial Venous Vascular Malformation with Injection of Bleomycin -- CASE 34. Percutaneous Puncture of a Facial Venous Malformation with Injection of Alcohol -- CASE 35.Transarterial Particle Embolization of a Facial Hemangioma -- PART V. Tumors -- CASE 36. Preoperative Transarterial Particle Embolization of a Meningioma -- CASE 37. Preoperative Transarterial Particle Embolization of a Juvenile Angiofi broma -- CASE 38. Preoperative Embolization of a Carotid Body Tumor -- CASE 39. Preoperative Embolization of a Recurrent Temporal Paraganglioma -- CASE 40. Preoperative Transarterial Embolization of a Spinal Hemangioblastoma -- CASE 41. Preoperative Embolization of a Hypervascular Vertebral Body Metastasis -- PART VI .Trauma -- CASE 42. Balloon Embolization of a Traumatic Carotid-Cavernous Fistula -- CASE 43. Coil Embolization of a Traumatic Carotid-Cavernous Fistula -- CASE 44. Carotid Artery Blowout -- CASE 45. Balloon Occlusion Test of a Traumatic Internal Carotid Artery Aneurysm Treated by Internal Carotid Artery Sacrifice with Detachable Balloons -- CASE 46. Transarterial Particle Embolization for Epistaxis -- PART VII. Stroke -- CASE 47. Intra-arterial rtPA Thrombolysis in Acute Ischemic Stroke -- CASE 48. Mechanical Thrombolysis in Acute Stroke with an Aspiration Device -- CASE 49. Mechanical Thrombectomy in Acute Stroke with a Retrievable Stent -- CASE 50. Stent-Assisted Angioplasty of a Symptomatic Extracranial Internal Carotid Artery Stenosis -- CASE 51. Stenting of a Symptomatic Post-surgical Internal Carotid Artery Stenosis -- CASE 52. Intracranial Revascularization with a Self-Expandable Stent -- CASE 53. Balloon-Mounted Intracranial Stenting of a High-Grade Vertebral Artery Stenosis -- CASE 54. Subclavian Steal Syndrome -- CASE 55. Direct Thrombolysis of Cerebral Venous Sinus Thrombosis -- PART VIII. Pediatric Vascular Interventions -- CASE 56. Transarterial Embolization of a Vein of Galen Aneurysmal Malformation -- CASE 57. Embolization of a Pial Arteriovenous Fistula in a Patient with Hereditary Hemorrhagic Telangiectasia -- CASE 58. Management of Pediatric Cerebral Aneurysm -- CASE 59. Transarterial Embolization of a Dural Sinus Malformation -- PART IX. Spine Vascular Interventions -- CASE 60. Spinal Dural Arteriovenous Fistulae: Successful Arterial Embolization -- CASE 61. Spinal Dural Arteriovenous Fistulae: Unsuccessful Arterial Embolization -- CASE 62. Spinal Arteriovenous Malformation of the Fistulous Type: Treatment with Liquid Embolic Material -- CASE 63. Spinal Arteriovenous Malformation of the Fistulous Type: Treatment with Coils -- CASE 64. Spinal Arteriovenous Malformation of the Glomerular or Nidus Type: Treatment withLiquid Embolic Material -- CASE 65. Balloon Embolization of a Vertebrovertebral Fistula -- PART X. Spine Percutaneous Interventions [p.393] CASE 66 Fluoroscopy-Guided Percutaneous Vertebral Biopsy -- CASE 67. Percutaneous Vertebroplasty in Osteoporotic Vertebral Compression Fracture -- CASE 68. Balloon-Assisted Kyphoplasty in Osteoporotic Vertebral Compression Fracture -- CASE 69. Multilevel Kyphoplasty in Multiple Myeloma -- CASE 70. Radiofrequency Kyphoplasty in an Osteoporotic Vertebral Compression Fracture -- CASE 71. Radiofrequency Kyphoplasty in Multiple Myeloma [p.426] CASE 72 Intra-articular Facet Joint Block -- Index.
  • 2011 Thieme Book
    [edited by] Kevin J. Donohoe, Annick D. Van den Abbeele.
    Skeletal scintigraphy -- Cardiac scintigraphy -- Pulmonary scintigraphy -- Endocrine scintigraphy -- Scintigraphy of neoplastic disease -- Radioisotope therapy -- Inflammation/Infection/Imaging -- Renal scintigraphy -- Biliary scintigraphy -- Lymphoscintigraphy -- CNS scintigraphy -- Gastrointestinal scintigraphy -- Vascular scintigraphy -- Pediatric scintigraphy
  • 2008 Springer
    David Ip.
  • 2009 WHO
    editors, Richard Cash, Daniel Wikler, Abha Saxena, Alexander M. Capron ; associate editor, Reva Gutnick.
    This casebook has been developed as a teaching tool for instructors and workshop leaders rather than as a textbook for students or workshop participants. There is no need for participants to have copies of the casebook: facilitators can provide participants with individual case studies and chapter introductions relevant to the research ethics topic being addressed. Individual case studies and chapter introductions relevant to the research ethics topic being addressed can be photocopied from the print version or downloaded from the WHO web site without additional permission from WHO, unless the planned use is in conjunction with commercial purposes.
    Also available: Print – 2009
  • 2009
    Haroutune K. Armenian.
    Status: Not Checked OutLane Catalog Record
    From case investigation to the case-control method : information for decision making -- Problem investigation and inferences using the case-control method -- Avoiding bias in case and control selection -- Avoiding information bias in exposure assessment -- Alternative case based designs -- Analysis of case-control data -- Applications : outbreak investigation -- Genetic epidemiology for case-based designs -- Applications : evaluation -- Applications : evaluation of screening programs -- Other applications.
  • 2010 ClinicalKey
    [edited by] Michael A. Gatzoulis [and others].
    Section One - Shunts -- Section Two - Left-sided lesions -- Section Three - Right-sided lesions -- Section Four - Complex congenital heart conditions -- Section Five - Special topics.
  • 2014 ClinicalKey
    [edited by] Cheuk-Man Yu, David L. Hayes, Angelo Auricchio.
    Cases in Cardiac Resynchronization Therapy, a brand-new medical reference book for cardiologists, electrophysiologists, surgeons, and primary care doctors, offers an informative and structured view of the newest approaches, treatments and follow-up care methods for heart failure patients treated with Cardiac Resynchronization Therapy. Complete with practical examples from top leaders in the field, this resource is designed to equip you with the cohesive, expert knowledge you need to make the best use of today's available technologies and research. Better manage the challenging clinical scenarios you may encounter with case studies that include a brief introduction, clinical decision-making techniques, evidence-based rationales, and selected references for further study.Remain up-to-date in this rapidly evolving field with clinical recommendations, updates on the latest technological advances, troubleshooting techniques, and recent key clinical trials.Access practical examples regarding the process for selecting and implanting devices, as well as follow-up care for heart-failure patients being treated with CRT.Stay abreast of today's novel wireless technologies, information on robotic-assisted implantations, and current methodologies on VV optimization.
  • 1980-
    edited by George R. Leopold.
    Status: Not Checked OutLane Catalog Record
  • 2015 Cambridge
    edited by Lauren C. Berkow, John C. Sakles.
    1. Anatomic consideration for airway management / Gail I. Randel and Tracey Straker -- 2. Airway algorithms and guidelines / Carlos A. Artime and Carin A. Hagberg -- 3. A general approach to management and evaluation of the emergency airway / Adam Schiavi and Christina Miller -- 4. Management of patients with angioedema / Wendy H. L. Teoh and Michael Seltz Kristensen -- 5. Stridor due to upper airway obstruction/mass / Sage P. Whitmore -- 6. Tracheostomy-related airway emergencies / Vinciya Pandian, Mueen Ahmad and Nasir Bhatti -- 7. Subglottic airway emergencies / Seth Manoach and Oren A. Friedman -- 8. Airway management in patients with tracheo-bronchial traumatic injury / Felipe Urdaneta -- 9. Airway management of the patient with morbid obesity / Davide Cattano and Ruggero M. Corso -- 10. Adult and pediatric epiglottitis / Calvin A. Brown, III -- 11. Management of foreign body aspiration in pediatric and adult patients / Neal Patrick Moehrle and Narasimhan Jagannathan -- 12. Management of anterior mediastinal mass / Basem Abdelmalak -- 13. The asthmatic crisis / Sal J. Suau and Peter M. C. DeBlieux -- 14. Airway management of the pregnant patient / Mohammed A. Abdel-Rahim, Lori Ann Wilkinson Suffredini and Jean-Pierre P. Ouanes -- 15. Management of patients with laryngospasm / Kenneth H. Butler -- 16. Airway compression by expanding hematoma / Michael Seltz Kristensen and Wendy H. L. Teoh -- 17. Extubation of the difficult airway / Richard M. Cooper --18. Management of blunt and penetrating neck trauma / Erik G. Laurin -- 19. Airway management of patients with smoke inhalation / Jarrod M. Mosier -- 20. Airway management in cervical spine injury / Jaime Daly and Keith J. Ruskin -- 21. Airway management in facial trauma / Rob Reardon and Marc Martel -- 22. Airway management in head injury / Christa San Luis and Athir Morad -- 23. Airway management of pediatric congenital anomalies / Paul Baker and Natasha Woodman -- 24. Management of post-tonsillectomy hemorrhage / Nick Dalesio -- 25. Fiberoptic intubation / William Rosenblatt and P. Allan Klock, Jr -- 26. Videolaryngoscopy for emergency intubation / Kenneth P. Rothfield and John C. Sakles -- 27. Surgical airway management / Aaron E. Bair -- 28. Communicating airway information: difficult airway letters and the MedicAlert National Difficult Airway/Intubation Registry / Lorraine Foley, Vinciya Pandian and Lynette Mark.
  • 2011 ClinicalKey
    Michael Ragosta.
    Section 1. Complex coronary interventions -- section 2. Complications -- section 3. Management dilemmas and controversies -- section 4. Peripheral and noncoronary interventions.
  • 2014 Springer Protocols
    edited by Peter V. Bozhkov, Department of Plant Biology, Uppsa;a BioCenter, Swedish University of Agricultural Science and Linnean Center for Plant Biology, Uppsala, Sweden, Guy Salvesen, Sanford-Burnham Medical Research Institute, La Jolla, CA, USA.
    General in vitro Caspase Assay Procedures -- Positional Scanning Substrate Combinatorial Library (PS-SCL) Approach to Define Caspase Substrate Specificity.- Global Identification of Caspase Substrates using PROTOMAP (PROtein TOpography and Migration Analysis Platform) -- Caspase-2 Protocols -- Caspase-14 Protocols -- Caspase Protocols in Caenorhabditis elegans -- Detecting Caspase Activity in Drosophila Larval Imaginal Discs -- Methods for the Study of Caspase Activation in the Xenopus laevis Oocyte and Egg Extract -- Caspase Protocols in Mice -- Measurement of Caspase Activation in Mammalian Cell Cultures -- Detection and Measurement of Paracaspase MALT1 Activity -- Leishmania Metacaspase: an Arginine-Specific Peptidase -- Purification, Characterization, and Crystallisation of Trypanosoma Metacaspases -- Monitoring the Proteostasis Function of the Saccharomyces cerevisiae Metacaspase Yca1 -- Plant Metacaspase Activation and Activity -- Preparation of Arabidopsis thaliana Seedling Proteomes for Identifying Metacaspase Substrates by N-terminal COFRADIC.
  • 2007 Thieme Book
    László Tabár, Tibor Tot, Peter B. Dean ; with contributions by Tony Hsiu-Hsi Chen [and others].
    The first of several satellite volumes to Tabar's Breast Cancer: The Art and Science of Early Detection with Mammography. Each volume will cover in depth a specific class of mammographic findings. Here, casting-type calcifications, and their significance in diagnosing cancer, are explored. Thick-section pathologic specimens are provided to help the reader understand why the mammograms look the way they do. A selection of full color pathologic images is provided in 3-D, allowing one to visualize the breast substructures in their spatial context.
  • 2002 ScienceDirect
    Bertram R. Payne and Alan Peters.
    The concept of cat primary visual cortex / Bertram R. Payne and Alan Peters -- Optical imaging of functional architecture in cat primary visual cortex / Mark Hubener and Tobias Bonhoeffer -- 2-Deoxyglucose architecture of cat primary visual cortex / Siegrid Lowel -- Functional mapping in the cat primary visual cortex using high magnetic fields / Dae-Shik Kim, Timothy Q. Duong, Kamil Ugurbil, and Seong-Gi Kim -- Relationships of LGN afferents and cortical efferents to cytochrome oxidase blobs / Joanne A. Matsubara and Jamie D. Boyd -- Influence of topography and ocular dominance on the functional organization of callosal connections in cat striate cortex / Jaime F. Olavarria -- Essential and sustaining LGN inputs to cat primary visual cortex / Theodore G. Weyand -- Integration of thalmic inputs to cat primary visual cortex / R. Clay Reid, Jose-Manuel Alonso, and W. Martin Usrey -- The emergence of direction selectivity in cat primary visual cortex / Allen L. Humphrey and Alan B. Saul -- Long-range intrinsic connections in cat primary visual cortex / Kerstin E. Schmidt and Siegrid Lowell -- Pharmacological studies on receptive field architecture / Ulf T. Eysel -- Orientation selectivity and its modulation by local and long-range connections in visual cortex / David Somers, Valentin Dragoi, and Mriganka Sur -- Response synchronization, gamma oscillations, and perceptual binding in cat primary visual cortex / Wolf Singer -- The special relationship between B Retinal ganglion cells and cat primary visual cortex / Bertram R. Payne and R. Jarrett Rushmore -- Primary visual cortex within the cortico-cortico-thalmic network / Jack W. Scannell and Malcolm P. Young -- Behavioral analyses of the contributions of cat primary visual cortex to vision / Donald E. Mitchell -- Index.
  • 1935-36.
    Status: Not Checked OutLane Catalog Record
  • 2008 Springer
    Dirk Proske.
  • 2013
    Helen Irene Wiersma-Koch.
    Catalytic promiscuity, the property of enzymes possessing low levels of activity toward non-cognate reactions, can be exploited as a functional tool to investigate conserved and non-conserved mechanism of enzyme specificity and catalysis between members in the same superfamily. Members of the main branch of the Alkaline Phosphatase (AP) superfamily have a structurally conserved core and active site bimetallo site. Other active site features that confer specificity for a given reaction differ between the families. Families within this superfamily catalyze a wide range of reactions, and enzymes within different families show catalytic promiscuity toward reactions catalyzed by other families within this branch. Structural comparisons and phylogenetic analysis suggests that all of the families in the superfamily arose from a common ancestor whose active site consisted of the bimetallo site alone, absent of peripheral, specificity determining features. Experimental data with a member of the nucleotide pyrophosphatase/phosphodiesterase (NPP) family suggests that a "minimal" mutant version of this enzyme that lacks peripheral, specificity determining features, has equal activity toward the two major reactions catalyzed by the AP superfamily, phosphate monoester and phosphate diester hydrolysis reactions. Together, the structural comparisons, phylogenic analysis, and experimental results lead to the hypothesis that the common ancestor of the AP superfamily is a "generalist." By using a variety of techniques, we provide support for a mechanism of evolution in which a "generalist" enzyme may give rise to multiple enzymes specific for, related, but individual reactions. Support for this mechanism, first proposed in 1976, has, until, now been limited. We suggest that this "generalist" mechanism is a valid mechanism for the evolution of ancient enzymes, present in the early evolution of life, into diverse superfamilies in which each family possesses specificity for one given reaction.
  • 2007
    Larry Benjamin.
    Status: Not Checked OutLane Catalog Record
    1 Introduction and general issues -- 2 Tools, facilities, and the operating team -- 3 Anesthesia for cataract surgery -- 4 Preparation for surgery -- 5 Wound placement and construction -- 6 Viscoelastics -- 7 Capsulorrhexis and capsule problems -- Hydrodissection -- 9 Nuclear strategies -- 10 Irrigation-aspiration -- 11 Lens implantation and its history -- 12 Postoperative care -- 13 Adjuncts for and management of complex cases -- 14 Management of complications -- 15 Lens exchange including refractive lens exchange -- 16 Wavefront aberrometry and cataract surgery.
  • 2009 Springer
    edited by Sandra Johnson.
    Part I. Cataract Surgery -- Approach to Cataract Surgery in Glaucoma Patients / Graham A. Lee and Ivan Goldberg -- Anesthesia / Marlene R. Moster and Augusto Azuara-Blanco -- Management of the Small Pupil / Cynthia Mattox -- Small Incision Cataract Surgery and Glaucoma / Brooks J. Poley, Richard L. Lindstrom, Thomas W. Samuelson, and Richard R. Schulze Jr. -- Elevated Intraocular Pressure After Cataract Surgery / Parag A. Gokhale and Emory Patterson -- Part II. Combined Surgery -- Combined Cataract and Trabeculectomy Surgery / Sandra M. Johnson -- Managing Cataract and Glaucoma in the Developing World - Manual Small Incision Cataract Surgery (MSICS) Combined with Trabeculectomy / Rengaraj Venkatesh, Rengappa Ramakrishnan, Ramasamy Krishnadas, Parthasarathy Sathyan, and Alan L. Robin -- Antimetabolite-Augmented Trabeculectomy Combined with Cataract Extraction for the Treatment of Cataract and Glaucoma / Sumit Dhingra and Peng Tee Khaw -- Early Postoperative Bleb Maintenance / Robert T. Chang and Donald L. Budenz -- Laser Suture Lysis and Releasable Sutures / Anastasios Costarides and Prathima Neerukonda -- Cataract Surgery Combined with Glaucoma Drainage Devices / Ramesh S. Ayyala and Brian J. Mikulla -- Choroidal Detachment Following Glaucoma Surgery / Diego G. Espinosa-Heidmann -- Cataract Extraction Combined with Endoscopic Cyclophotocoagulation / Steven D. Vold -- Approach to Cataract Extraction Combined with New Glaucoma Devices / Diamond Y. Tam and Iqbal Ike K. Ahmed -- Part III. Glaucoma Conditions -- Cataract Surgery in Patients with Exfoliation Syndrome / Anastasios G.P. Konstas, Nikolaos G. Ziakas, Miguel A. Teus, Dimitrios G. Mikropoulos, and Vassilios P. Kozobolis -- Cataract Surgery in the Presence of a Functioning Trabeculectomy Bleb / Hylton R. Mayer and James C. Tsai -- Cataract Extraction in Eyes with Prior GDD Implantation / Ramesh Ayyala and Brian Mikulla -- Cataract Surgery in the Primary Angle-Closure Patient / Jimmy S.M. Lai -- Nanophthalmos / Carlos Gustavo Vasconcelos de Moraes and Remo Susanna Jr. -- Cataract Induced Glaucoma: Phacolytic/Phacomorphic / Sandra M. Johnson -- Glaucoma Related to Pseudophakia / Junping Li and Jason Much -- Cataract and Glaucoma in Retinopathy of Prematurity / Anthony J. Anfuso and M. Edward Wilson -- Cataract Surgery in the Hypotonous Eye / Devon Ghodasra and Sandra M. Johnson.
  • 2014 Springer
    Hiroko Bissen-Miyajima, Douglas Donald Koch, Mitchell Patrick Weikert, editors.
    Cataract Surgery: Maximizing Outcomes Through Research provides cataract surgeons with helpful information about cataract operations based on the latest fundamental and clinical research. This book comprehensively covers a wide range of topics from the basic principles of each treatment to today?s hot topics such as femtosecond laser application, cataract surgery, and new intraocular lenses (IOLs) with accommodating or light-adjustable function. Detailed cutting-edge discussion is provided in each chapter with the addition of diagrams, photographs, and tables to help readers better understand the subject. Authored by leading international experts, the book covers topics from preoperative evaluations to postoperative care including evaluation of accommodation and pseudo-accommodation, glistening and visual function, the eye?s image quality with a premium IOL, IOL power calculations, pupil size and postoperative visual function, posterior capsular opacity, corneal astigmatism, femtosecond laser techniques, and more. Cataract Surgery: Maximizing Outcomes Through Research is the perfect book for cataract surgeons and general ophthalmologists who wish to update their knowledge and make use of it in their everyday medical practice.
  • 2010 ClinicalKey
    editor, Roger F. Steinert ; associate editors, David F. Chang [and others].
    The pathology of cataracts -- Surgical anatomy, biochemistry, pathogenesis, and classification of cataracts -- Preoperative evaluation of the patient with visually significant cataract -- Intraocular lens power calculation -- Intraocular lens power calculations after refractive surgery -- Ophthalmic viscosurgical devices: physical characteristics, clinical applications, and complications -- The phaco machine: the physical principles guiding its operation -- Retrobulbar and peribulbar anesthesia for cataract surgery -- Topical intracameral anesthesia -- Extracapsular cataract surgery: indications and techniques -- Small incision cataract surgery in underdeveloped countries -- Prophylactic preoperative preparation and operative measures for control of infection, inflammation and intraocular pressure -- Incision construction -- Capsulorrhexis -- Hydrodissection and hydrodelineation -- Principles of nuclear phacoemulsification -- Phaco chop -- Tilt and tumble phacoemulsification: coaxial and bimanual -- Biaxial phacoemulsification -- Microcoaxial phacoemulsification with torsional ultrasound -- Phacoemulsification in the presence of a small pupil -- Combined cataract implant and filtering surgery -- Combined cataract extraction and corneal transplantation -- Control of astigmatism in the cataract patient -- Cataract surgery in uveitis patients -- Surgical management of pediatric cataracts and aphakia -- The intumescent cataract -- Dense brunescent cataract -- Capsule tension rings and segments -- Techniques and principles of surgical management for the traumatic cataract -- Iris repair -- High myopia -- Nanophthalmos, relative anterior microphthalmos, and axial hyperopia -- Cataract surgery in the presence of other ocular comorbidities -- The evolution of the intraocular lens -- Polymethylmethacrylate intraocular lenses -- Foldable intraocular lenses, edge design, and aspheric optics -- Presbyopia correcting intraocular lenses -- The correction of astigmatism during cataract surgery with toric intraocular lenses -- Intraocular lens spectral filtering -- Secondary intraocular lens implantation and stabilization -- Pathology of cataract surgery and intraocular lenses -- Risk management in cataract surgery -- Intraoperative complications of phacoemulsification surgery -- Anterior vitrectomy techniques for the cataract surgeon -- Surgical repositioning and explanation of the intraocular lens -- Issues in wound management -- Toxic anterior segment syndrome -- Corneal edema after cataract surgery -- Glaucoma after cataract surgery -- Neodymium:yttrium-aluminum-garnet laser posterior capsulotomy -- Neodymium:yttrium-aluminum-garnet laser in the management of postoperative complications of cataract surgery -- Ingrowths -- Macular causes of poor postoperative vision: cystoid macular edema, epiretinal fibrosis, and age-related macular degeneration -- Postoperative endophthalmitis -- Management of postoperative complications: retinal detachment -- Prolonged intraocular inflammation -- Cataract surgery: future predictions.
  • 2013
    David Goldhill.
    "In 2007, David Goldhill's father died from a series of infections acquired in a well-regarded New York hospital. The bill was for several hundred thousand dollars--and Medicare paid it. These circumstances left Goldhill angry and determined to understand how it was possible that world-class technology and well-trained personnel could result in such simple, inexcusable carelessness--and how a business that failed so miserably could be rewarded with full payment. Catastrophic Care is the eye-opening result. Goldhill explicates a health-care system that now costs nearly $2.5 trillion annually, bars many from treatment, provides inconsistent quality of care, offers negligible customer service, and in which an estimated 200,000 Americans die each year from errors. Above all, he exposes the fundamental fallacy of our entire system--that Medicare and insurance coverage make care cheaper and improve our health--and suggests a comprehensive new approach that could produce better results at more acceptable costs immediately by giving us, the patients, a real role in the process." -- [Provided by publisher]
  • 2013 ScienceDirect
    [editor] Lee E. Eiden.
    Through the use of extended graphical abstracts and some traditional text-only abstracts this collection provides, a record of and roadmap to, the research presented at The Tenth International Catecholamine Symposium (XICS) held in September of 2012. Organized around ten general themes, each is introduced by a short overview identifying interesting research programs, results and potential areas of growth. The collection is a roadmap to key research and future opportunities for new catecholamine research programs and will be of interest to neuroscientists and clinical neurologists interested in understanding the current and future state of catecholamine research..
  • 2006 Springer
    C. Schmitt, I. Deisenhofer, B. Zrenner (eds.).
  • 2015 ClinicalKey
    [edited by] Shoei K. Stephen Huang, John M. Miller.
    1. Biophysics of Radiofrequency Lesion Formation -- 2. Guiding Lesion Formation During Radiofrequency Energy Catheter Ablation -- 3. Irrigated- and Cooled-Tip Radiofrequency Catheter Ablation -- 4. Catheter Cryoablation : Biophysics and Applications -- 5. Alternative Energy Sources and Ablative Techniques : Ultrasound, Laser, and Microwave, Biophysics and Applications -- 6. Cardiac Anatomy for Catheter Mapping and Ablation of Arrhythmias -- 7. Fundamentals of Intracardiac Mapping -- 8. Advanced Catheter Three-Dimensional Mapping Systems -- 9. Remote Catheter Navigation Systems -- 10. Role of Intracardiac Echocardiography in Clinical and Experimental Electrophysiology -- 11. Ablation of Focal Atrial Tachycardias -- 12. Ablation of Cavotricuspid Isthmus-Dependent Atrial Flutters -- 13. Ablation of Nonisthmus-Dependent Flutters and Atrial Macroreentry -- 14. Ablation of Postoperative Atrial Tachycardia in Congenital Heart Disease -- 15. Pulmonary Vein Isolation for Atrial Fibrillation -- 16. Catheter Ablation of Paroxysmal Atrial Fibrillation Originating from the Nonpulmonary Vein Areas -- 17. Substrate-Based Ablation for Atrial Fibrillation -- 18. Focal Impulse and Rotor Modulation for Ablation of Atrial Fibrillation -- 19. Stepwise Approach for Ablation of Persistent Atrial Fibrillation -- 20. Epicardial and Endocardial Hybrid Procedures for Ablation of Atrial Fibrillation -- 21. Ablation of Atrioventricular Junctional Tachycardias: Atrioventricular Nodal Reentry, Variants, and Focal Junctional Tachycardia -- 22. Atrioventricular Junction Ablation and Modification for Heart-Rate Control of Atrial Fibrillation -- 23. Ablation of Free-Wall Accessory Pathways -- 24. Ablation of Posteroseptal Accessory Pathways -- 25. Ablation of Superoparaseptal (Anteroseptal) and Midseptal Accessory Pathways -- 26. Ablation of Atriofascicular Accessory Pathways and Variants -- 27. Special Problems in Ablation of Accessory Pathways -- 28. Ablation of Ventricular Outflow Tract Tachycardias -- 29. Ablation of Idiopathic Left and Right Ventricular and Fascicular Tachycardias -- 30. Ablation of Ventricular Tachycardia in Coronary Artery Disease -- 31. Ablation of Ventricular Tachycardia Associated with Nonischemic Cardiomyopathy -- 32. Ablation of Unstable Ventricular Tachycardia and Idiopathic Ventricular Fibrillation -- 33. Epicardial Approach to Catheter Ablation of Ventricular Tachycardia -- 34. Ablation of Ventricular Tachycardia with Congenital Heart Disease -- 35. Complications Associated with Radiofrequency Catheter Ablation of Arrhythmias -- 36. Atrial Transseptal Catheterization -- 37. Special Considerations for Ablation in Pediatric Patients -- 38. Catheter Ablation of Scar-Related Ventricular Tachycardia with Percutaneous Hemodynamic Support
  • 2013 Springer
    Peter Lanzer, editor.
    Operator skills, and in particular decision-making and strategic skills, are the most critical factor for the outcome of catheter-based cardiovascular interventions. Currently, such skills are commonly developed by the empirical trial and error method only. In this textbook, for the first time, an explicit teaching, training, and learning approach is set out that will enable interventional operators, whether cardiologists, vascular surgeons, vascular specialists, or radiologists, to learn about and to develop the cognitive skills required in order to achieve consistent expert-level catheter-based interventions. It is anticipated that adoption of this approach will allow catheter-based interventions to become a domain of excellence, with rapid transfer of knowledge, steep learning curves, and highly efficient acquisition of complex skills by individual operators -- all of which are essential if we are to meet successfully the challenges of modern cardiovascular care embedded in highly competitive health care markets.
  • 2012 Springer
    Sasha Rudenstine, Sandro Galea.
    pt. 1. The study of disasters -- pt. 2. Causes of disasters -- pt. 3. Behavioral consequences of disasters -- pt. 4. Our models : applying a public health perspective.
  • 2011 Cambridge
    edited by Simon D. Shorvon, Frederick Andermann, Renzo Guerrini.
    Part I. Introduction -- Part II. Idiopathic Epilepsy -- Part III. Symptomatic Epilepsy -- Part IV. Provoked Epilepsies -- Part V. Status Epilepticus.
  • 2012 Springer
    edited by Jean-François Jasmin, Philippe G. Frank, Michael P. Lisanti.
    Lipid rafts, caveolae, and GPI linked proteins / Valerie L. Reeves, Candice M. Thomas, and Eric J. Smart -- Caveolae and the regulation of endocytosis / Anna L. Kiss -- Caveolin : role in cell signaling / Cecile Boscher and Ivan Robert Nabi -- Regulation of ENOS in caveolae / Chieko Mineo and Philip W. Shaul -- Recent developments in the interactions between caveolin and pathogens / Fabiana S. Machado ... [et al.] -- Caveolin and breast cancer : a new clinical perspective / Isabelle Mercier and Michael P. Lisanti -- Caveolin and prostate cancer progression / Michael R. Freeman, Wei Yang, and Dolores Di Vizio -- Caveolins and caveolae, roles in insulin signalling, and diabetes / Peter Strolfors -- Atherosclerosis, caveolae, and caveolin / Stephanos Pavlides ... [et al.] -- Caveolins and heart diseases / Mathivadhani Panneerselvam, Hemal H. Patel, and David M. Roth -- Caveolins and lung function / Nikolaos A. Maniatis ... [et al.].
    Also available: Print – 2012
  • 2012 Springer
    Isabelle Mercier, Jean-François Jasmin, Michael P. Lisanti, editors.
    1. Local and Distant Effects of Caveolin-1 on Prostate Cancer Progression / T.C. Thompson, S.A. Tahir, L. Li, M. Watanabe, K. Naruishi, G. Yang, Ken-ichi Tabata, S. Kurosaka, K. Edamura, R. Tanimoto, P. Corn, D. Kadmon, C.J. Logothetis, P. Troncoso, C. Ren, A. Goltsov, and S. Park -- 2. Caveolin-1 in Colon Cancer: The Flexible Connection to Wnt Signaling / Andrew F.G. Quest, Vicente A. Torres, Diego A. Rodriguez, Jorge Gutierrez-Pajares, and Julio C. Tapia -- 3. Caveolin-1 and Pancreatic Ductal Adenocarcinoma / David W. Rittenhouse, Oeendree Mukherjee, Nathan G. Richards, Charles J. Yeo, Agnieszka K. Witkiewicz, and Jonathan R. Brody -- 4. Caveolin-1 in Brain Tumors / Rebecca Senetta and Paola Cassoni -- 5. The Role of Caveolin-1 in Skin Cancer -- / Alessandra Carè, Isabella Parolini, Federica Felicetti, and Massimo Sargiacomo -- 6. Caveolins in Tumor Angiogenesis / Grzegorz Sowa -- 7. Caveolin-1 and Breast Cancer / Gloria Bonuccelli and Michael P. Lisanti -- 8. Caveolin-1 and Cancer-Associated Stromal Fibroblasts / Isabelle Mercier and Michael P. Lisanti.
  • 2008 Thieme eNeurosurgery
    Giuseppe Lanzino, Robert F. Spetzler.
    A comprehensive overview of the basic science and current clinical knowledge on cavernous malformations of the brain and spinal cord. Cavernous Malformations of the Brain and Spinal Cord begins by covering general aspects of the disease, including the natural history, molecular biology, pathological processes, genetic basis, neuroradiology, and classification of cavernous malformations. Separate chapters then address the various types of cavernous malformations, thoroughly describing the clinical presentation and management approaches for each clinical situation. Incisive review of recent literature sheds light on topics of incidence, location, and outcomes. Neurosurgeons, neurologists, and neuroradiologists, especially those caring for patients with seizures and hemorrhagic stroke, will benefit from the information in this complete reference.
  • 2009 Springer
    Vinko V. Dolenc, Larry Rogers (eds.).
  • 2014 Wiley
    Alex Clarke, Andrew Thompson, Elizabeth Jenkinson, Nichola Rumsey, and Rob Newell.
    Background, clinical problems, common presentation and treatment considerations -- A stepped-care approach to psychosocial intervention -- Models and frameworks: expanding the conceptual approach to managing appearance-related distress -- Clinical assessment -- Social skills and coping strategies -- Cognitive behavioral therapy -- Planning treatment and sessional guides -- The emerging adult: facilitating transition from child to adult service -- Psychological assessment for cosmetic surgery -- Models of service delivery.
  • 2010 Springer
    Annick Perbal, Masaharu Takigawa, Bernard Perbal, editors.
    1. A Recent Breakthrough in the CCN Field: Functional Interactions Between CCN2 and CCN3 are Uncovered / Bernard Perbal -- 2. Report on the Fifth International Workshop on the CCN Family of Genes / A. E. Irvine, B. Perbal, and H. Yeger -- 3. Asking the Right Questions: What Can the Structure of the CCN Protein Domains Tell Us? / Kenneth P. Holbourn, Bernard Perbal, and K. Ravi Acharya -- 4. Nucleophosmin/B23: A Multifunctional Regulator that Determines the Fate of CCN2 mRNA / Satoshi Kubota, Yoshiki Mukudai, Harumi Kawaki, Seiji Kondo, Takanori Eguchi, Kumi Sumiyoshi, Toshihiro Ohgawara, Tsuyoshi Shimo, and Masaharu Takigawa -- 5. The CCN Genes as the “Master” Regulators of Angiogenesis, Vasculogenesis, Fibrogenesis and Cell Differentiation/Fate Specification in Mechanical Force-Driven Developmental Processes and Pathological Events / Mary Hanna and Brahim Chaqour -- 6. A Monoclonal Antibody Approach to CCN5 Domain Analysis / Lan Wei, Frank McKeon, Joshua W. Russo, Joan Lemire, and John Castellot -- 7. Matricellular Protein CCN2 Produced by Tubular Epithelial Cells Plays a Pivotal Role in Renal Fibrogenesis / Hirokazu Okada, Tsutomu Inoue, and Hiromichi Suzuki -- 8. Cooperative Regulation of Cell Proliferation and Differentiation by CCN2 and CCN3 / Masaharu Takigawa, Harumi Kawaki, Satoshi Kubota, Karen M. Lyons, and Bernard Perbal -- 9. The Role of CCN3 in Mesenchymal Stem Cells / Ken-Ichi Katsube -- 10. Role of Connective Tissue Growth Factor in Cardiac Fibrosis / Daiji Kawanami, Saptarsi M. Haldar, and Mukesh K. Jain -- 11. Gene Expression of CCN Family Members in Young and Aged Human Skin In Vivo / Taihao Quan, Sharon Shin, Zhaoping Qin, and Gary J. Fisher -- 12. Global Expression Profiling Reveals a Role for CTGF/CCN2 in Lactogenic Differentiation of Mouse Mammary Epithelial Cells / Weihan Wang, Cynthia Jose, Nicholas Kenney, Bethanie Morrison, and Mary Lou Cutler -- 13. CCN3 (NOV): A Negative Regulator of CCN2 (CTGF) Activity and an Endogenous Inhibitor of Fibrosis in Experimental Diabetic Nephropathy / Bruce. L. Riser, Feridoon Najmabadi, Bernard Perbal, Jo Ann Rambow, Melisa L. Riser, Ernest Sukowski, Herman Yeger, Sarah C. Riser, and Darryl R. Peterson -- 14. Inhibitors of Connective Tissue Growth Factor (CCN2)-Mediated Fibrogenesis: Underlying Mechanisms and Prospects for Anti-fibrotic Therapy / David R. Brigstock -- 15. CCN3 Promotes Melanoma Progression by Regulating Integrin Expression, Adhesion and Apoptosis Induced by Cytotoxic Drugs / Viviana Vallacchi, Maria Daniotti, Annamaria De Filippo, Licia Rivoltini, Bernard Perbal, and Monica Rodolfo -- 16. CCN3: A NOVel Growth Factor in Leukaemia / Lynn McCallum and Alexandra E Irvine -- 17. Prognostic Relevance of CCN3 in Bone Sarcomas / Bernard Perbal, Noureddine Lazar, Diana Zambelli, Monia Zuntini, Massimo Serra, Jose Antonio Lopez-Guerrero, Antonio Llombart-Bosch, Piero Picci, and Katia Scotlandi -- 18. CCN6 Regulates Breast Cancer Growth and Invasion Through Modulation of IGF Signaling and Epithelial to Mesenchymal Transition / Anupama Pal, Wei Huang, and Celina G. Kleer -- 19. Novel Transcriptional Regulation of CCN2/CTGF by Nuclear Translocation of MMP3 / Takanori Eguchi, Satoshi Kubota, Kazumi Kawata, Yoshiki Mukudai, Junji Uehara, Toshihiro Ohgawara, Soichiro Ibaragi, Akira Sasaki, Takuo Kuboki, and Masaharu Takigawa -- Fifth International Workshop on the CCN Family of Genes: Abstracts and Posters October 18-22, 2008.
  • 2004-2010
    by Laura Gasparis Vonfrolio.
    Presents a two-day review course intended to prepare nurses for the CCRN certification exam. Topics include Cardiac, Pulmonary, Endocrine, Hematology, Neurological, Gastrointestinal and Renal.
  • 2009/2010
    Siddhartha Jaiswal.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    edited by Lieping Chen.
  • 2011
    Michael Nathaniel Alonso.
    Monocytes rapidly infiltrate inflamed tissues and differentiate into inflammatory dendritic cells (DCs) that mediate pathogen clearance. However, the cellular and molecular mechanisms governing inflammatory DC formation and subsequent function remain elusive. Current evidence suggests that conserved molecular patterns present on different classes of microbes that engage pattern recognition receptors on DCs dictate the type of immune response initiated by DCs. Given that pathogens are under evolutionary pressure to avoid elimination, we reasoned that memory T cells were better positioned to inform the immune response. The studies presented in this dissertation indicate that memory T cells dictate the nature of the immune response through the induction of functionally specialized inflammatory DCs. Our studies indicate that T-helper (TH) cells interact with monocytes in inflamed tissues and instruct monocytes to differentiate into inflammatory DCs in vivo. This process is antigen-driven and requires cell contact, GM-CSF and TNF[alpha]. Interestingly, distinct TH cell subsets direct the formation of specialized DC subsets. In psoriasis lesions, TH1 and TH17 cells interact with monocytes and instruct these cells to differentiate into TH1- and TH17-promoting DCs, respectively. Correspondingly, in acute atopic dermatitis, TH2 cells interact with monocytes and elicit the formation of TH2-promoting DCs. Again, DC formation required GM-CSF and cell contact, whereas TH subset specific cytokines dictate DC function and the expression of DC subset specific surface molecules. Moreover, the phenotypes of T cell induced DC subsets are maintained following subsequent stimulation with a panel of toll-like receptor (TLR) agonists, suggesting that TH-derived signals outweigh downstream TLR signals in their influence on DC function. Our preliminary studies indicate that regulatory T cells promote the formation of tolerogenic DCs that are typically associated with tumor progression and poor patient prognosis. The data indicate that intra-tumoral Tregs frequently interact with monocytes within tumor tissue and instruct monocytes to differentiate into IL-10-producing tolerogenic DCs. Such Treg-induced DCs (DCTreg) are subsequently able to instruct naïve T cells to differentiate into FoxP3+, IL-10-producing regulatory T cells with potent suppressive activity. The capacity of Tregs to elicit DCTreg formation represents a physiologic mechanism that on one hand amplifies and perpetuates immune tolerance, but also contributes to attenuated anti-tumor immune responses. We also explored mechanisms capable of depleting inflammatory DCs. While previous studies have indicated that inflammatory DC depletion through systemic elimination of their monocyte precursors with clodronate-loaded liposomes ameliorates pathogenesis in psoriasis and other diseases, translation of these strategies into the clinic is difficult due the importance of monocytes in the clearance of infection. We describe three strategies that avoid the monocyte intermediates in order to directly prevent inflammatory DC formation or deplete inflammatory DCs through antibody-loaded toxins. These strategies provide useful tools for the targeted reduction of inflammatory DCs during disease pathogenesis. In summary, memory T cells dictate the nature of the immune response through the induction of functionally specialized inflammatory DCs. The system we utilized for generating DC subsets with differential TH polarizing capacity has facilitated the elucidation of cell surface and soluble factors governing the biology of TH-promoting DC subsets. These and additional molecules expressed by DC subsets should prove useful for detecting and quantifying each subset in situ and may enable the design of novel therapeutic strategies for T[not]H-associated inflammatory diseases.
  • 2011 Springer
    Keith W. Boone.
    Organization of This Book -- Clinical Documentation -- The HL7 Clinical Document Architecture -- Extensible Markup Language -- Basic Data Types -- Text and Multimedia -- Demographic Data -- Codes and Vocabularies -- Codes -- Dates and Times -- Collections -- HL7 Version 3 Modeling -- Clinical Document Infrastructure -- The CDAtm Header -- The CDAtm Body -- Clinical Statements in the CDAtm -- HL7 Version 2 to CDAtm Release 2 -- Extracting Data from a CDAtm Document -- Templates -- Validating the Content of a CDAtm Document -- Implementation Guides on CDAtm.
  • 2005 Springer
    B. Kyewski and E. Suri-Payer (eds.).
    Also available: Print – yyyy
  • 2013
    Ming Tatt Cheah.
    Keratin 14 (KRT14) expression marks the most primitive differentiation state in bladder cancer (BC) cells. However, the mechanisms by which KRT14-expressing cells promote tumorigenicity remain undefined. We found that KRT14-expressing cells express higher levels of CD14 and inflammatory factors such as IL6 and IL8. Using a syngeneic mouse BC model, we isolated CD14 high BC cells and show that this population is more tumorigenic compared to CD14 low cells and forms tumors that are more highly vascularized with higher myeloid cell infiltration. Inflammatory factors produced by CD14 high BC cells directly drive the recruitment and polarization of monocytes and macrophages to acquire immune-suppressive characteristics. In contrast, CD14 low BC cells have higher relative proliferation, which is markedly increased when stimulated by factors produced by CD14 high cells. Collectively, we demonstrate that CD14 high BC cells orchestrate tumor-promoting inflammation and drive tumor cell proliferation to promote tumor growth.
  • 2011 Springer Protocols
    edited by Chaofu Lu, John Browse, and James G. Wallis.
  • ScienceDirect
    edited by Sherman M. Weissman.
    cDNA preparation -- Gene identification -- Patterns of mRNA expression -- Functional relationship among cDNA translation products.
    Also available: Print – 1999
  • 2008
    edited by Lee Goldman, Dennis Ausiello ; associate editors, William P. Arend ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2010
    Christine E. Hallett ; foreword by Joan E. Lynaugh.
    Status: Not Checked OutLane Catalog Record
    Looks at the development of the profession, describes the work of nurses through the ages, and depicts the work of nurses in peace and wartime.
  • 2014 Springer
    edited by S. Devi Rampertab, Gerard E. Mullin.
    Celiac Disease is an authoritative text intended to educate healthcare practitioners, gastroenterologists, physicians and nutritionists about the diverse manifestations, complications and management of gluten-sensitive enteropathy. The seventeen-chapter text provides the latest research on pathophysiology, including animal models, immunopathogenesis, genetics and the intestinal microflora. The book also features chapters on diagnosis, monitoring, complications and nutritional management, including therapies on the horizon. The text concludes with appendices that provide educational tools for symptom monitoring and dietary guidance. Written by specialists in their respective fields, "Celiac Disease" is a comprehensive resource that provides the healthcare practitioner an evidence-based practical guide to pathogenesis and therapy of celiac disease.
  • 2004 NLM
    prepared by Karen Patrias, Carolyn C. Willard, Frank A. Hamilton ; United States National Library of Medicine, National Institutes of Health.
  • 2014 ScienceDirect
    Herbert Wieser, Peter Koehler, Katharina Konitzer.
    Celiac disease : a complex disorder -- Gluten : the precipitating factor -- Treatment of Celiac disease -- Gluten-free products.
  • 2015 Springer Protocols
    edited by Anthony W. Ryan.
    Celiac disease : background and historical context / Graham D. Turner, Margaret R. Dunne, and Anthony W. Ryan -- Celiac disease : diagnosis / Greg Byrne and Conleth F. Feighery -- Generating transgenic mouse models for studying celiac disease / Josephine M. Ju, Eric V. Marietta, and Joseph A. Murray -- Study designs for exploring the non-HLA genetics in celiac disease / Åsa Torinsson Naluai -- Twenty-four hour ex vivo culture of celiac duodenal biopsies / Sarah E. J. Cooper, Sharon Wilson, and Conleth F. Feighery -- Isolation and cloning of gluten-specific T cells in celiac disease / Yvonne Kooy-Winkelaar and Frits Koning -- Flow cytometric analysis of human small intestinal lymphoid cells / Margaret R. Dunne -- Adaptation of a cell-based high content screening system for the in-depth analysis of celiac biopsy tissue / Sarah E. J. Cooper ... [et al.] -- HLA genotyping : methods for the identification of the HLA-DQ2,-DQ8 heterodimers implicated in celiac disease (CD) susceptibility / Maria Edvige Fasano, Ennia Dametto, and Sandra D'Alfonso -- Detecting allelic expression imbalance at candidate genes using 5' exonuclease genotyping technology / Jillian M. Gahan ... [et al.] -- Gene expression profiling of celiac biopsies and peripheral blood monocytes using taqman assays / Martina Galatola, Renata Auricchio, and Luigi Greco -- Cloning gene variants and reporter assays / Ben Molloy and Ross McManus -- Epigenetic methodologies for the study of celiac disease / Antoinette S. Perry, Anne-Marie Baird, and Steven G. Gray -- Candidate gene knockdown in celiac disease / Ben Molloy ... [et al.] -- Perl one-liners : bridging the gap between large data sets and analysis tools / Karsten Hokamp -- Bioinformatic analysis of antigenic proteins in celiac disease / Cathal P. O'Brien -- Quality control procedures for high-throughput genetic association studies / Ciara Coleman, Emma M. Quinn, and Ross McManus -- Quality control and analysis of NGS RNA sequencing data / Emma M. Quinn and Ross McManus.
  • 2006 Springer
    edited by Anne E. Cress and Raymond B. Nagle.
  • 2014 Springer
    Christian Behl, Christine Ziegler.
    Aging and cell aging : an introduction -- Cell cycle : the life cycle of a cell -- Theories and mechanisms of aging -- Selected age-related disorders.
  • 2013 Springer
    Heide Schatten, editor.
    Histopathology and grading of breast cancer / Magda Esebua -- Multicentric/multifocal breast cancer : overview, biology, and therapy / Federico Buggi ... [et al.] -- Immune system in breast cancer initiation and progression : role of epithelial to mesenchymal transition / Keith L. Knutson and Erik C. Radisky -- Remodelling of the extracellular matrix : implication for cancer / Thomas R. Cox and Janine T. Erler -- Biology and treatment of basal-like breast cancer / Bingchen Han ... [et al.] -- Re-excision after lumpectomy for breast cancer / Suzanne B. Coopey -- Novel anti-angiogenic therapies using naturally occurring and synthetic drugs to combat progestin-dependent breast cancer / Salman M. Hyder, Benford Mafuvadze, and Cynthia Besch-Williford -- New insights on estrogen receptor actions in hormone-responsive breast cancer cells by interaction proteomics / Concetta Ambrosino ... [et al.] -- Reprogramming breast cancer cells with embryonic microenvironments : insights from nodal signaling / Gina Kirsammer and Mary J.C. Hendrix - Metastatic determinants : breast tumour cells in circulation / Nisha Kanwar and Susan J. Done -- Breast cancer epigenetics : biomarkers and therapeutic potential / Nancy H. Nabilsi ... [et al.] -- Impact of centrosome abnormalities on breast cancer development and progression with a focus on targeting centrosomes for breast cancer therapy / Heide Schatten -- New perspective on cyclin D1 : beyond cell cycle regulation / Chenguang Wang, Timothy G. Pestell, and Richard G. Pestell -- Gene signatures of inflammatory breast cancer : epithelial plasticity and a cancer stem cell phenotype / Fredika M. Robertson ... [et al.] -- Integrated human mammary epithelial cell culture system for studying carcinogenesis and aging / Martha R. Stampfer, Mark A. LaBarge, and James C. Garbe -- New breast cancer treatment considerations a brief review of the use of genetically modified (attenuated) bacteria as therapy for advanced and metastatic breast cancer / Robert A. Kazmierczak ... [et al.].
  • 2007 Springer
    Ralph Bock (ed.).
  • 2009 ClinicalKey
    edited by Raymond R. Tubbs, Mark H. Stoler.
    This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you're getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today's technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.
  • 2002 ScienceDirect
    edited by Brian Matsumoto.
    Also available: Print – 2002
  • 2006 ScienceDirect
    edited by Julio E. Celis.
  • 2010 Springer
    edited by Eran Meshorer, Kathrin Plath.
    Early embryonic cell fate decisions in the mouse / Yojiro Yamanaka and Amy Ralston -- Nuclear architecture in stem cells / Kelly J. Morris, Mita Chotalia, and Ana Pombo -- Epigenetic regulation of pluripotency / Eleni M. Tomazou and Alexander Meissner -- Autosomal lyonization of replication domains during early mammalian development / Ichiro Hiratani and David M. Gilbert -- Preservation of genomic integrity in mouse embryonic stem cells / Peter J. Stambrook and Elisia D. Tichy -- Transcriptional regulation in embryonic stem cells / Jian Chien, Dominic Heng, and Huck Hui Ng -- Alternative splicing in stem cell self renewal and differentiation / David A. Nelles and Gene W. Yeo -- MicroRNA regulation of embryonic stem cell self renewal and differentiation / Collin Melton and Robert Blelloch -- Telomeres and telomerase in adult stem cells and pluripotent embryonic stem cells / Rosa M. Marión and Maria A. Blasco -- X chromosome inactivation and embryonic stem cells / Tahsin Stefan Barakat and Joost Gribnau -- Adult stem cells and their niches / Francesca Ferraro, Cristina Lo Celso, and David Scadden -- Adult stem cell differentiation and trafficking and their implications in disease / Ying Zhuge, Zhao-Jun Liu, and Omaida C. Velazquez -- Vertebrates that regenerate as models for guiding stem cells / Christopher L. Antos and Elly M. Tanaka -- Reprogramming of somatic cells to pluripotency / Masato Nakagawa and Shinya Yamanaka.
    Also available: Print – 2010
  • 2009 Springer
    Edward Koenig (ed.).
    Also available: Print – 2009
  • 2006 Springer
    Eckart D. Gundelfinger, Constanze I. Seidenbecher, Buckhart Schraven (eds.).
    Also available: Print – 2006
  • 2002 CRCnetBASE
    edited by Claus-Michael Lehr.
  • 2011 Springer Protocols
    edited by Michael Aschner, Cristina Suñol, Anna Bal-Price.
    Guidance on Good Cell Culture Practice (GCCP) -- Induced Pluripotent Stem Cells (iPSCs): An Emerging Model System for the Study of Human Neurotoxicology -- Neural Stem Cells -- Primary Cultures for Neurotoxicity Testing -- Preparation and Use of Serum-Free Aggregating Brain Cell Cultures for Routine Neurotoxicity Screening -- Cell Culture to Investigate Neurotoxicity and Neurodegeneration Utilizing Caenorhabditis elegans -- Modeling the Blood-Brain Barrier -- In vitro Models of the Blood-Cerebrospinal Fluid Barrier and Their Use in Neurotoxicological Research -- Introducing Cloned Genes into Cultured Neurons Providing Novel In vitro Models for Neuropathology and Neurotoxicity Studies -- P19 Embryonic Carcinoma Cell Line: A Model To Study Gene-Environment Interactions -- Signal Transduction and Neurotoxicity: What Can We Learn from Experimental Culture Systems? -- Neurite Degeneration in Human Neuronal SH-SY5Y Cells as an Indicator of Axonopathy -- The Use of Differentiating N2a and C6 Cell Lines for Studies of Organophosphate Toxicity -- Assessing Toxic Injuries of Experimental Therapeutics to the Crystalline Lens Using Lens Explant Culture -- Necrosis, Apoptosis, and Autophagy: Mechanisms of Neuronal and Glial Cell Death -- Inflammation and Reactive Oxygen/Nitrogen Species in Glial/Neuronal Cultures -- Neuronal Oxidative Injury and Biomarkers of Lipid Peroxidation -- Analysis of Protein Targets by Oxidative Stress Using the Oxyblot and Biotin-Avidin-Capture Methodology -- Catecholaminergic Cell Lines for the Study of Dopamine Metabolism and Neurotoxicity -- 13C NMR Spectroscopy and Mass Spectrometry Analysis of Intermediary Metabolism in Cultured Neural Cells -- Culture Models for the Study of Amino Acid Transport and Metabolism -- Neurotransmitter Transporters and Anticonvulsant Drug Development -- Ion Channel Electrophysiology in Cultured Neurons -- Neurotoxicity Assessment by Recording Electrical Activity from Neuronal Networks on Microelectrode Array Neurochips -- GABAA Receptor Binding and Ion Channel Function in Primary Neuronal Cultures for Neuropharmacology/Neurotoxicity Testing.
  • 2005 CRCnetBASE
    edited by Sadettin S. Ozturk, Wei-Shou Hu.
  • 2011 Springer Protocols
    edited by Willis X. Li.
    Studying G2 DNA damage checkpoints using the fission yeast Schizosaccharomyces pombe / Nicholas Willis and Nicholas Rhind -- Studying S-phase DNA damage checkpoints using the fission yeast Schizosaccharomyces pombe / Nicholas Willis and Nicholas Rhind -- Methods for studying the G2 DNA damage checkpoint in mammalian cells / Claudia Tapia-Alveal and Matthew J. O'Connell -- Evaluating spindle assembly checkpoint competence in mouse oocytes using immunoblotting / Hayden Homer -- Analysis of changes in protein level and subcellular localization during cell cycle progression using the budding yeast Saccharomyces cerevisiae / Xiaorong Wu, Lili Liu, and Mingxia Huang -- Studying cell cycle checkpoints using Drosophila cultured cells / Katarzyna Siudeja, Jannie de Jong, and Ody C.M. Sibon -- In vivo live-analysis of cell cycle checkpoints in Drosophila early embryos / Saeko Takada and Byeong J. Cha -- Using Drosophila larval imaginal discs to study low-dose radiation-induced cell cycle arrest / Shian-Jang Yan and Willis X. Li -- Screening for radiation sensitizers of Drosophila checkpoint mutants / Mara Gladstone and Tin Tin Su -- Study of cell cycle checkpoints using Xenopus cell-free extracts / Seetha V. Srinivasan and Jean Gautier -- Analyzing DNA replication dynamics of genotoxin-treated cells using velocity sedimentation / Tovah A. Day, Chris Sproul, Marila Cordeiro-Stone, and Cyrus Vaziri -- Methods for studying checkpoint kinases-Chk1 / Claudia Tapia-Alveal and Matthew J. O'Connell -- A human cell extract-based assay for the activation of ATM and ATR checkpoint kinases / Bunsyo Shiotani and Lee Zou -- Analyzing p53 regulated DNA damage checkpoints by flow cytometry / Lois Resnick-Silverman and James J. Manfredi -- Using Drosophila S2 cells to measure S phase-coupled protein destruction via flow cytometry / Jean M. Davidson and Robert J. Duronio -- Assessing G1-to-S-phase progression after genotoxic stress / Michael DeRan, Mary Pulvino, and Jiyong Zhao -- Indirect immunofluorescence for monitoring spindle assembly and disassembly in yeast / Jacob W.P. Keeling and Rita K. Miller -- Detecting recruitment of DNA damage response factors through the eChIP approach / Yucai Wang and Lei Li -- Methods to study cancer therapeutic drugs that target cell cycle checkpoints / Yun Dai and Steven Grant.
  • ScienceDirect
    edited by William G. Dunphy.
    Also available: Print – 1997
  • 2014 Springer Protocols
    edited by Eishi Noguchi and Mariana C. Gadaleta.
    Cell cycle-regulated transcription : effectively using a genomics toolbox / Sara L. Bristow, Adam R. Leman, and Steven B. Haase -- Cell cycle regulation by checkpoints / Kevin J. Barnum and Matthew J. O'Connell -- Interplacy between the cell cycle and double-strand break response in mammalian cells / Kate Beishline and Jane Azizkhan-Clifford -- Cell cycle regulation by protein degradation / Deanna M. Koepp -- Linking chromosome duplication and segregation via sister chromatid cohesion / Adam R. Leman and Eishi Noguchi -- The greatwall : PP2A axis in cell cycle control / Peng Wang, Marcos Malumbres, and Vincent Archambault -- Cell cycle regulation by the nutrient-sensing mammalian target of rapamycin (mTOR) pathway / Elisabet Cuyàs ... [and 3 others] -- The senescence arrest program and the cell cycle / Alessandro Bitto ... [and 4 others] -- Oncogenic Ras pushes (and pulls) cell cycle progression through ERK activation / Paul M. Campbell -- Cell cycle regulation during viral infection / Sumedha Bagga and Michael J. Bouchard -- The roles of cohesins in mitosis, meiosis, and human health and disease / Amanda S. Brooker and Karen M. Berkowitz -- Introductory review of computational cell cycle modeling / Andres Kriete, Eishi Noguchi, and Christian Sell -- Cell cycle synchronization and flow cytometry analysis of mammalian cells / Naoko Yoshizawa-Sugata and Hisao Masai -- Analyzing transcription dynamics during the budding yeast cell cycle / Adam R. Leman, Sara L. Bristow, and Steven B. Haase -- Analyzing cell cycle checkpoints in response to ionizing radiation in mammalian cells / Bin Wang -- Analyzing DNA replication checkpoint in budding yeast / Nicole Hustedt and Kenji Shimada -- Analyzing cell cycle-dependent degradation and ubiquitination in budding yeast / Dong-Hwan Kim and Deanna M. Koepp -- Imaging analysis of cell cycle-dependent degradation of Cdt1 in mammalian cells Yasushi Shiomi ... [and 4 others] -- PCNA-dependent ubiquitination of Cdt1 and p21 in mammalian cells / Akiyo Hayashi ... [and 3 others] -- Analyzing Cdc2/Cdk1 activation during stress response in Schizosaccharomyces pombe / Miguel A. Rodríguez-Gabriel -- Analyzing Ras-associated cell proliferation signaling / Matthew C. Stout ... [and 4 others] -- Telomere regulation during the cell cycle in fission yeast / Bettina A. Moser, Ya-Ting Chang, and Toru M. Nakamura -- Detecting senescence : methods and approaches / Elizabeth P. Crowe ... [and 5 others] -- Analyzing RB and E2F during the G1-S transition / Michael J. Thwaites, Matthew J. Cecchini, and Frederick A. Dick -- Analyzing G1-S transcriptional control / Steffi Klier, Sarah Farmer, and Robertus A.M. de Bruin -- Analysis of replication timing using synchronized budding yeast cultures / Jie Peng, M.K. Raghuraman, and Wenyi Feng -- Analysis of ssDNA gaps and DSBs in genetically unstable yeast cultures / Jie Peng, M.K. Raghuraman, and Wenyi Feng -- Chromatin fractionation analysis of licensing factors in mammalian cells / Hideo Nishitani ... [and 4 others] -- Imaging analysis to determine chromatin binding of the licensing factor MCM2-7 in mammalian cells / Masayuki Morino ... [and 3 others] -- Chromatin immunopreciptiation to investigate origin association of replication factors in mammalian cells / Adam R. Leman and Eishi Noguchi -- Live-cell fluorescence imaging for phenotypic analysis of mitosis / Sushama Sivakumar, John R. Daum, and Gary J. Gorbsky -- Analyzing sister chromatid cohesion in mammalian cells / Katherine M. Feeney, Laura McFarlane-Majeed, and Joanna L. Parish -- Affinity purification of protein complexes from Drosophila embryos in cell cycle studies / Zoltan Lipinszki ... [and 8 others] -- Tracking histone variant nucleosomes across the human cell cycle using biophysical, biochemical, and cytological analyses / Marcin P. Walkiewicz ... [and 3 others].
  • 2010 Springer
    Greg H. Enders, editor.
    Part I: Starting the Cell Division Cycle -- 1 Escape from Cellular Quiescence -- 2 Interplay Between Cyclin-Dependent Kinases and E2F-Dependent Transcription -- 3 Regulation of Pre-RC Assembly: A Complex Symphony Orchestrated by CDKs -- Part II: Proliferation Under Duress -- 4 Mitotic Checkpoint and Chromosome Instability in Cancer -- 5 Mitotic Catastrophe -- 6 p53, ARF, and the Control of Autophagy -- Part III: Long-Term Proliferation -- 7 Regulation of Self-Renewing Divisions in Normal and Leukaemia Stem Cells -- 8 Maintenance of Telomeres in Cancer -- 9 The Senescence Secretome and Its Impact on Tumor Suppression and Cancer -- Part IV: Applications in Preventing and Treating Cancer -- 10 Cell Cycle Deregulation in Pre-neoplasia: Case Study of Barrett8217;s Oesophagus -- 11 Targeting Cyclin-Dependent Kinases for Cancer Therapy -- Index.
  • 2010
    Stacey Ellen Wirt.
    The ability of stem/progenitor cells to exit the cell cycle is essential for proper embryonic development, but the mechanisms governing cell cycle exit are still not fully understood. Correct regulation of G1 is critical for ensuring proper organismal development, tissue homeostasis, and tumor suppression. The Retinoblastoma (Rb) gene family is composed of three genes, Rb, p107, and p130, which are collectively thought to serve as essential regulators of the G1 phase of the cell cycle in most proliferating cell types. The Rb family has also been implicated in promoting the gene expression of several differentiation programs in different cell lineages. However, due to the overlapping and compensatory functions among the Rb family members, a complete understanding of how the Rb family controls the cell cycle and differentiation programs within a cell remains unclear. Furthermore, it has not yet been tested whether the Rb family members are the only mediators of these cellular processes, or if there are alternative mechanisms for cell cycle exit and differentiation in mammalian stem and progenitor cells. Here we tested the requirement for the Rb protein and its family members p107 and p130 in G1 arrest and differentiation in mammalian cells. We employed several strategies to conditionally remove the Rb family genes in entire embryos and in specific neural lineages, as well as multiple differentiation systems in vitro. We found that Rb family triple knock-out (TKO) mouse embryos survive until days 9-11 of gestation, with similar patterning and organogenesis as seen in wild type embryos. Strikingly, a number of TKO cells, including in the neural lineage, are able to exit the cell cycle in G1 and fully differentiate in vivo and in culture. This ability of TKO cells to arrest in G1 is associated with the repression of key cell cycle target genes for E2F and Myc transcription factors. Thus, G1 arrest can be achieved independently of Rb family members, illustrating the robustness of cell cycle regulatory networks during embryogenesis, and identifying a novel program that regulates cell cycle exit in G1 in mammalian cells.
  • 2011 Springer
    Jacek Z. Kubiak, editor.
    Also available: Print – 2011
  • 2006 Springer
    edited by Damir Janigro.
    Methodological considerations in the evaluation of cell cycle in the central nervous system / Richard A. Prayson -- Neural stem cells / Philippe Taupin -- Progenitors and precursors of neurons and glial cells / Monika Bradl -- Vaculogenesis and angiogenesis / Gerald A. Grant and Damir Janigro -- Neuronal migration and malformation of cortical development / Giorgio Battaglia and Stefania Bassanini -- Genome-wide expression profiling of neurogenesis in relation to cell cycle exit / P. Roy Walker ... [et al.] -- Neurogenesis and apoptotic cell death / Klaus van Leyen ... [et al.] -- Ion channels and cell cycle / Annarosa Arcangeli and Andrea Becchetti -- Nonsynaptic GABAergic communication and postnatal neurogenesis / Xiuxin Liu, Anna Bolteus, and Angélique Bordey -- Critical roles of Ca2+ and K+ homeostasis in apoptosis / Shan Ping Yu -- Mammalian neural stem-cell renewal / Yvan Arsenijevic -- Methods of determining apoptosis in neuro-oncology: review of the literature / Brian T. Ragel ... [et al.] -- Cell cycle, neurological disorders, and reactive gliosis / Kerri L. Hallene and Damir Janigro -- Potassium channels, cell cycle and tumorigenesis in the central nervous system / Gabriele Dini, Erin V. Ilkanich, and Damir Janigro -- Enhanced neurogenesis following neurological disease / Philippe Taupin -- Endothelial injury and cell cycle re-entry / Ljiliana Krizanac-Bengez -- The contribution of bone marrow-derived cells to cerebrovascular formation and integrity / David Kobiler and John Glod -- Microvessel remodeling in cerebral ischemia / Danica B. Stanimirovic, Maria J. Moreno, and Arsalan S. Haqqani -- Vascular and neuronal effects of VEGF in the nervous system: implications for neurological disorders / Lieve Moons, Peter Carmeliet, and Mieke Dewerchin -- Epidermal growth factor receptor in the adult brain / Carmen Estrada and Antonio Villalobo -- Neurodegeneration and loss of cell cycle control in postmitotic neurons / Randall D. York, Samantha A. Cicero, and Karl Herrup -- Cell cycle activation and the amyloid-[beta] protein in Alzheimer's disease / Katarzyna A. Gustaw ... [et al.] -- Neuronal precursor proliferation and epileptic malformations of cortical development / Jorge A González-Martínez, William E. Bingaman, and Imad M. Najm -- Vascular differentiation and cell cycle / Luca Cucullo -- Adult neurogenesis and central nervous system cell cycle analysis: novel tools for exploration of the neural causes and correlates of psychiatric disorders / Amelia J. Eisch and Chitra D. Mandyam -- Neurogenesis and Alzheimer's disease: compensation, crisis, or chaos? / Gemma Casadesus ... [et al.] -- P53 and multidrug resistance transporters in the central nervous system / Shirley Teng and Micheline Piquette-Miller -- Signaling modules in glial tumors and implications for molecular therapy / Gurpreet S. Kapoor and Donald M. O'Rourke -- Detection of proliferation in gliomas by positron emission tomography imaging / Alexander M. Spence ... [et al.] -- Transition of normal astrocytes into a tumor phenotype / Sean E. Aeder and Isa M. Hussaini -- Mechanisms of gliomagenesis / Wei Zhang and Howard A. Fine -- Cell cycle of encapsulated cells / Roberto Dal Toso and Sara Bonsiegna -- Viral vector delivery to dividing cells / Yoshinaga Saeki -- Electrical stimulation and angiogenesis: electrical signals have direct effects on endothelial cells / Min Zhao -- Development and potential therapeutic aspects of mammalian neural stem cells / L. Bai, S.L. Gerson, and R.H. Miller -- Mammalian Sir2 proteins: a role in epilepsy and ischemia / Barbara Aumayr and Damir Janigro.
  • 2016 Springer Protocols
    edited by Amanda S. Coutts, Louise Weston.
  • 2006 Springer
    Philipp Kaldis (ed.).
    Also available: Print – 2006
  • 2010 Springer
    Antonio Giordano, Umberto Galderisi, editors.
  • 2011 Springer Protocols
    edited by Gaspar Banfalvi.
    1. Overview of cell synchronization / Gaspar Banfalvi -- 2. Synchronization of mammalian cells and nuclei by centrifugal elutriatio / Gaspar Banfalvi -- 3. Cytofluorometric purification of diploid and tetraploid cancer cells / Maria Castedo, Lorenzo Galluzzi, Ilio Vitale, Laura Senovilla, Didier Métivier, Mohamed Jèmaà, Santiago Rello-Varona, and Guido Kroemer -- 4. Large-scale mitotic cell synchronization / Kalyan Dulla and Anna Santamaria -- 5. Synchronization of mammalian cell cultures by serum deprivation / Thomas J. Langan and Richard C. Chou -- 6. Cell synchronization by inhibitors of DNA replication induces replication stress and DNA damage response: analysis by flow cytometry / Zbigniew Darzynkiewicz, H. Dorota Halicka, Hong Zhao, and Monika Podhorecka -- 7. Chromosome formation during fertilization in eggs of the teleost oryzias latipes / Takashi Iwamatsu -- 8. Specific cell cycle synchronization with butyrate and cell cycle analysis / Congjun Li -- 9. Analysis of nuclear uracil-DNA glycosylase (nUDG) turnover during the cell cycle / Jennifer A. Fischer and Salvatore Caradonna -- 10. Synchronization of HeLa cells / Hoi Tang Ma and Randy Y. C. Poon -- 11. Synchronization of Bacillus subtilis cells by spore germination and outgrowth / Gasper Banfalvi -- 12. Synchronization of yeast / Arkadi Manukyan, Lesley Abraham, Huzefa Dungrawala, and Brandt L. Schneider -- 13. Synchronization of pathogenic protozoans / Staffan Svärd and Karin Troell -- 14. Synchronization of in vitro maturation porcine oocytes / Tamas Somfai and Yuji Hirao -- 15. Synchronization of medicago sativa cell suspension culture / Ferhan Ayaydin, Edit Kotogány, Edit Ábrahám, and Gábor V. Horváth -- 16. Cell cycle synchronization for the purpose of somatic cell nuclear transfer (SCNT) / Yoel Shufaro and Benjamin E. Reubinoff -- 17. Ex vivo expansion of haematopoietic stem cells to improve engraftment in stem cell transplantation / Kap-Hyoun Ko, Robert Nordon, Tracey A. O'Brien, Geoff Symonds, and Alla Dolnikov -- 18. Flow cytometry developments and perspectives in clinical studies: examples in ICU patients / Fabienne Venet, Caroline Guignant, and Guillaume Monneret -- 19. Molecular network dynamics of cell cycle control: transitions to start and finish / Attila Csikász-Nagy, Alida Palmisano, and Judit Zámbprszky.
  • 2006 CRCnetBASE
    edited by Andrew D. Badley.
    Also available: Print – 2006
  • 2011 Springer
    by Gerardo H. Vázquez-Nin, María Luisa Escobar, M. De Felici, Olga Margarita Echeverría, Francesca Gioia Klinger.
    [Publisher-supplied data] The ovary is a suitable organ for studying the processes of cell death. Cell death was first described in the rabbit ovary (Graaffian follicles), the phenomenon being called chromatolysis. To date, it is recognized that various forms of cell death (programmed cell death, apoptosis and autophagy) are essential components of ovarian development and function. Programmed cell death is responsable for the ovarian endowment of primordial follicles around birth; in the prepuberal and adult period, apoptosis is a basic mechanism by which oocytes are eliminated by cancer therapies and environmental toxicants; in the ovarian cycle, follicular atresia and luteal regression involve follicular cell apoptosis. Finally, abnormalities in cell death processes may lead to ovarian disease such as cancer and chemoresistance. In this book, after an introductory description of various forms of cell death and of the ovary development and function in mammals, the processes of cell death in ovarian somatic cells and oocytes are described at cytological, physiological and molecular levels and analyzed in the embryonic, prepuberal and adult ovary. A complex array of molecular pathways triggered by extrinsic and intrinsic signals able tor induce or suppress cell death in the same cell, according to cell type and ovary developmental stage, emerges. Physiological interactions with the axis hypothalamus-hypophysis as well as ovarian internal functional signal are also critically reviewed to explain the abortive development of follicles before the beginning of the ovarian cycle. The book conveys information useful to the updating of biologists and physicians who are interested to the ovary biology and functions. Hopefully it should provide also clues for stimulating novel experiments in the study of cell death in the mammalian ovary still at an early stage.
  • 2014 Springer
    Hao Wu, editor.
    Beginning from centuries of anecdotal descriptions of cell death, such as those on the development of the midwife toad in 1842 by Carl Vogt, to modern-day investigations of cell death as a biological discipline, it has become accepted that cell death in multicellular organisms is a normal part of life. This book provides a comprehensive view of cell death, from its mechanisms of initiation and execution, to its implication in human disease and therapy. Physiological cell death plays critical roles in almost all aspects of biology, and the book details its roles in lymphocyte homeostasis, neuronal function, metabolism, and the DNA damage response.?When physiological cell death goes awry, diseases can arise, and cancer is presented as a central paradigm for the consequences of derangements in the interplay between cell survival and cell death. At the same time, the potential promise of targeted therapies aimed at interdicting cell death machineries are also discussed extensively. The molecular mechanisms that underlie apoptotic cell death are illustrated from the perspectives of both the intrinsic, mitochondrial apoptotic pathway and the extrinsic, death receptor pathway. Key players in these pathways, such as the Bcl2 family proteins, cytochrome c, Apaf-1, caspases, death receptor adapter proteins, and inhibitor of apoptosis proteins, are presented from both functional and structural angles. Until only a few years ago, programmed cell death has been considered essentially synonymous with apoptosis. However, we now know that programmed cell death can also take other forms such as necrosis or necroptosis, and to this end, the mechanisms that underlie programmed necrosis in development and host defense are illustrated. The past twenty plus years have seen an incredible growth of research in cell death, with one breakthrough after another, and the legacy still goes on with constant new surprises and findings. Long live cell death!
  • 2013 Springer
    Daniel E. Johnson, editor.
    Defects in cell death pathways promote tumor development and progression, with potentially devastating consequences for cancer patients. Greater understanding of the defects occurring in cancer cells, and the unique characteristics of tumors which can make them vulnerable to cell death stimuli, offers tremendous opportunities for developing novel and effective anti-cancer therapies. In Cell Death in Cancer Biology and Treatment leading experts in the field provide a wealth of up-to-date knowledge regarding the molecular mechanisms and cell biological processes that control cell death. Each chapter also highlights recent advances in the translation of basic research findings into clinical trials. Beginning and established investigators alike will benefit from the thorough presentations of the most promising avenues for future development of cell death-based, anti-cancer strategies and agents. The volume begins with a detailed description of many of the cell death defects that have been identified in human tumor specimens. The unique bioenergetics of cancer cells, and the influence of the tumor microenvironment, autophagy, and cellular microRNAs on cancer cell death are then discussed, along with current progress in targeting these distinctive features and processes. Additional chapters describe recent advances, and the therapeutic benefits of targeting DNA repair pathways, protein chaperones, sphingolipid signaling, Bcl-2 family members, IAPs, death receptor signaling, the proteasome, and survival signaling emanating from the PI3K/AKT and RAS/RAF/MEK/ERK pathways. Finally, recent discoveries are presented regarding interactions between the immune system and dying cancer cells and the potential for optimizing these interactions to maximize anti-cancer activities. In summary, Cell Death in Cancer Biology and Treatment will be a valuable resource for scientists interested in cutting-edge understanding of aberrant cell death in cancer cells, and the multitude of innovative molecular targeting approaches that are actively being pursued to achieve selective activation of cell death in human malignancies.
  • v. 1-, 1999- Springer
    Al-Rubeai, Mohamed.
  • 2010 Springer
    John E. Johnson, editor.
    Preface / John E. Johnson, Peter K. Vogt -- Flock House Virus: A model system for understanding non-enveloped virus entry and membrane penetration / Amy Odegard, Manidipa Banerjee and John. E. Johnson -- The calciviruses / Umesh Katpally and Thomas J. Smith -- Picornaviruses / Tobias J. Tuthill ... [et al.] -- From touchdown to transcription: The reovirus cell entry pathway / Pranav Danthi ... [et al.] -- Rotavirus cell entry / Matthew Baker and B.V. Venkataram Prasad -- Structures and functions of parvovirus capsids and the process of cell infection / Colin R. Parrish -- Cellular entry of polyomaviruses / Billy Tsai and Mengding Qian -- Adenovirus / Jason G. Smith ... [et al.].
    Also available: Print – 2010
  • 2011 Springer
    Thomas Dittmar, Kurt S. Zänker, editors.
    1. Introduction / Thomas Dittmar and Kurt S. Zänker -- 2. Heterochronic control of AFF-1-mediated cell-to-cell fusion in C. elegans / Lilach Friedlander-Shani and Benjamin Podbilewicz -- 3. Role of SNAREs in membrane fusion / Bhanu P. Jena -- 4. Molecular and cellular mechanisms of mammalian cell fusion / Xiaofeng Zhou and Jeffrey L. Platt -- 5. Membrane fusions during mammalian fertilization / Bart M. Gadella and Janice P. Evans -- 6. Trophoblast fusion / Berthold Huppertz and Martin Gauster -- 7. Macrophage fusion and multinucleated giant cells of inflammation / Amy K. McNally and James M. Anderson -- 8. Molecular mechanisms of myoblast fusion across species / Adriana Simionescu and Grace K. Pavlath -- 9. Cell-fusion-mediated reprogramming : pluripotency or transdifferentiation? : implications for regenerative medicine / Daniela Sanges, Frederic Lluis, and Maria Pia Cosma -- 10. Cell fusion and tissue regeneration / Manuel Álvarez-Dolado and Magdalena Martínez-Losa -- 11. Dendritic cell-tumour cell fusion vaccines / Walter T. Lee.
    Also available: Print – 2011
  • 2011 Springer
    Thomas Dittmar, Kurt S. Zänker, editors.
    Introduction / Thomas Dittmar and Kurt S. Zänker -- Horizontal Gene Transfers with or without Cell Fusions in All Categories of the Living Matter / Joseph G. Sinkovics -- Class III Viral Membrane Fusion Proteins / Marija Backovic and Theodore S. Jardetzky -- Human Trophoblast in Trisomy 21: A Model for Cell - Cell Fusion Dynamic Investigation / André Malassiné, Guillaume Pidoux, Pascale Gerbaud, Jean Louis Frendo and Danièle Evain-Brion -- Cell Fusion and Hyperactive Osteoclastogenesis in Multiple Myeloma / Franco Silvestris, Sabino Ciavarella, Sabino Strippoli and Franco Dammacco -- Cell Fusion Hypothesis of the Cancer Stem Cell / Xin Lu and Yibin Kang -- Expression of Macrophage Antigens by Tumor Cells / Ivan Shabo and Joar Svanvik -- Leukocyte-Cancer Cell Fusion: Initiator of the Warburg Effect in Malignancy? / Rossitza Lazova, Ashok Chakraborty and John M. Pawelek -- Cell Fusion, Drug Resistance and Recurrence CSCs / Christa Nagler, Kurt S. Zänker and Thomas Dittmar -- The Role of Microvesicles in Malignancies / Erna Pap.
    Also available: Print – 2011
  • 2015 Springer Protocols
    edited by Kurt Pfannkuche.
    This volume details protocols on detection and analysis of fusion events in various cell types in vitro and in vivo. Additional, protocols aim to facilitate the future highly relevant process of engineering cells for specific purposes, such as generation of transgenic embryos and development of hybrid cells, in order to tackle specific tasks in cell biology and medicine. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and authoritative, Cell Fusion: Overviews and Methods, Second Edition serves as an ideal reference on cell fusion and laboratory protocols.
  • 2008 Springer Protocols
    edited by Elizabeth H. Chen.
    Pt. 1. Cell fusion -- 1. Yeast mating, a model system for studying cell and nuclear fusion / Casey A. Ydenberg, Mark D. Rose -- 2. Cell fusion in the filamentous fungus, neurospora crassa / André Flei€ner, Anna R. Simonin, N. Louise Glass -- 3. Gametic cell adhesion and fusion in the uicellular alga chlamydomonas / Nedra F. Wilson -- 4. Cell Fusion in caenorhabditis elegans / Scott Alper, Benjamin Podbilewicz -- 5. Myoblast fusion in drosophila / Susan M. Abmayr, Shufei Zhuang, and Erika R. Geisbrecht -- 6. Mammalian fertilization is dependent on multiple membrane fusion events / Paul M. Wassarman, Eveline S. Litscher -- 7. Molecular control of mammalian myoblast fusion / Katie M. Jansen, Grace K. Pavlath -- 8. Placenta trophoblast fusion / Berthold Huppertz, Marcus Borges -- 9. Macrophage fusion / Agnès Vignery -- Pt. 2. Cell fusion assays -- 10. Cell fusion assays for yeast mating pairs / Eric Grote -- 11. Ultrastructural analysis of cell fusion in yeast / Alison E. Gammie -- 12. Isolation and in vitro binding of mating type plus fertilization tubules from chlamydomonas / Nedra F. Wilson -- 13. Optical imaging of cell fusion and fusion proteins in caenorhabditis elegans / Star Ems, William A. Mohler -- 14. Ultrastructural imaging of cell fusion in caenorhabditis elegans / Star Ems, William A. Mohler -- 15. Live imaging of drosophila myoblast fusion / Brian E. Richardson, Karen Beckett, Mary K. Baylies -- 16. Ultrastructural Analysis of myoblast fusion in drosophila / Shiliang Zhang, Elizabeth H. Chen -- 17. Genomic approach to myoblast fusion in drosophila / Beatriz Estrada, Alan M. Michelson -- 18. Mesenchymal cell fusion in the sea urchin embryo / Paul G. Hodor, Charles A. Ettensohn -- 19. Sperm-egg fusion assay in mammals / Naokazu Inoue, Masaru Okabe -- 20. Quantitative assays for cell fusion / Jessica H. Shinn-Thomas, Victoria L. Scranton, William A. Mohler -- 21. Fusion assays and models for the trophoblast / Sascha Drewlo, ... [et al.] -- 22. Methods to fuse macrophages in vitro / Agnès Vignery.
  • 2011 Springer
    Lars-Inge Larsson, editor.
  • 2009
    Maria Lynn Spletter.
    The brain is a complex organ formed from billions of neurons. There are thousands of types of neurons, each with a unique morphology, function, gene expression profile and pattern of connectivity. This structure poses a very interesting developmental challenge: how do neurons acquire unique identities and connect to specific partner neurons during development? The Drosophila antennal lobe presents an attractive genetic model system in which to investigate these questions. In the antennal lobe, olfactory receptor neuron (ORN) axons project to glomeruli where they synapse with their partner projection neuron (PN) dendrites. These connections are highly stereotyped, as ORNs expressing the same odorant receptor converge on the same glomerulus and all PNs of the same class send their dendrites to the same glomerulus. Cell surface molecules are known to be crucial to instructing this specific wiring during development, and a transcriptional code likely dictates which cells express a particular cell surface molecule. However, the identities of many of these cell surface molecules and transcription factors remain unknown, and it is possible that additional cell types also inform the specific wiring of PNs and ORNs. In this thesis, I present work that furthers our understanding of the development and function of the fly olfactory circuit. First, I discuss a detailed characterization of local interneurons in the antennal lobe, dramatically expanding our basic knowledge of the types of cells present during development as well as central to information processing in the antennal lobe. Second, I present my work on the transcription factor longitudinals lacking (lola) that plays a role both in fate determination and wiring specificity of olfactory projection neurons, the second order cells that relay olfactory information to higher brain centers. Finally, I present an analysis of the regulatory elements driving expression of the projection neuron marker GH146 as a first step in defining transcriptional regulatory modules and identifying factors that may direct fate and wiring decisions in PNs.
  • 2012 Springer Protocols
    edited by Douglas J. Taatjes, Jürgen Roth.
    Digital images are data : and should be treated as such / Douglas W. Cromey -- Epi-fluorescence microscopy / Donna J. Webb and Claire M. Brown -- Live-cell migration and adhesion turnover assays / J. Lacoste, K. Young, and Claire M. Brown -- Multifluorescence confocal microscopy : application for a quantitative analysis of hemostatic proteins in human venous valves / Winifred E. Trotman, Douglas J. Taatjes, and Edwin G. Bovill -- Colocalization analysis in fluorescence microscopy / Jeremy Adler and Ingela Parmryd -- A time-lapse imaging assay to study nuclear envelope breakdown / Sunita S. Shankaran, Douglas R. Mackay, and Katharine S. Ullman -- Light sheet microsocopy in cell biology / Raju Tomer, Khaled Khairy, and Philipp J. Keller -- Image-based high-throughput screening for inhibitors of angiogenesis / Lasse Evensen, Wolfgang Link, and James B. Lorens -- Intravital microscopy to image membrane trafficking in live rats / Andrius Masedunskas [and others] -- Imaging non-fluorescent nanoparticles in living cells with wavelength-dependent differential interference contrast microscopy and planar illumination microscopy / Wei Sun, Lehui Xiao, and Ning Fang -- Laser scanning cytometry : principles and applications-an update / Piotr Pozarowski, Elena Holden, and Zbigniew Darzynkiewicz -- Laser capture microdissection for protein and NanoString RNA analysis / Yelena Golubeva [and others] -- Viewing dynamic interactons of proteins and a model lipid membrane with atomic force microscopy / Anthony S. Quinn [and others] -- Mica functionaliztion for imaging of DNA and protein-DNA complexes with atomic force microscopy / Luda S. Shlyakhtenko, Alexander A. Gall, and Yuri Lyubchenko -- Measuring the elastic properties of living cells with atomic force microscopy indentation / Joanna L. MacKay and Sanjay Kumar -- Atomic force microscopy functional imaging on vascular endothelial cells / Lilia A. Chtcheglova and Peter Hinterdorfer -- Porosome : the secretory nanomachine in cells / Bhanu P. Jena -- Stereology and morphometry of lung tissue / Christian Mühlfeld, Lars Knudsen, and Matthias Ochs -- A novel combined imaging/morphometrical method for the analysis of human sural nerve biopsies for clinical diagnosis / Michele A. vonTurkovich [and others] -- Correlative light-electron microscopy as a tool to study in vivo dynamics and ultrastructure of intracellular structures / Elena V. Polishchuk, Roman S. Polishchuk, and Alberto Luini -- Photooxidation technology for correlative light and electron microscopy / Claudia Meisslitzer-Ruppitsch [and others] -- Electron microscopy of endocytic pathways / Carmen Ranftler [and others] -- Morphological analysis of autophagy / Keisuke Tabata [and others] -- Cytochemical detection of peroxisomes and mitochondria / Nina A. Bonekamp [and others] -- Histochemical detection of lipid droplets in cultured cells / Michitaka Suzuki, Yuki Shinohara, and Toyoshi Fujimoto -- Environmental scanning electron microscopy in cell biology / J.E. McGregor [and others] -- Environmental scanning electron microscopy gold immunolabeling in cell biology / Francesco Rosso, Ferdinando Papale, and Alfonso Barbarisi -- High-pressure freezing for scanning transmission electron tomography analysis of cellular organelles / Paul Walther, Eberhard Schmid, and Katharina Höhn -- MALDI imaging mass spectrometry for direct tissue analysis / Stephan Meding and Axel Walch.
  • 2009 Springer
    edited by Mohamed Al-Rubeai.
    Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This book deals with the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhance productivity and improve cell function.
  • 2007 ScienceDirect
    edited by Yu-Li Wang, Dennis E. Discher.
    Also available: Print – 2007
  • 2011 Springer Protocols
    edited by Claire M. Wells, Maddy Parsons.
    Cell migration : an overview / Miguel Vicente-Manzanares and Alan Rick Horwitz -- Scratch-wound assay / Giles Cory -- HGF-induced DU145 cell scatter assay / Sally T. Fram, Claire M. Wells, and Gareth E. Jones -- Using the dunn chemotaxis chamber to analyze primary cell migration in real time / Sanjay Chaubey, Anne J. Ridley, and Claire M. Wells -- Imaging cells within 3D cell-derived matrix / Samantha J. King and Maddy Parsons -- Live cell imaging of neuronal growth cone motility and guidance in vitro / Daniel M. Suter -- Boyden chamber / Marco Falasca, Claudio Raimondi, and Tania Maffucci -- Transwell® invasion assays / John Marshall -- Imaging podosome dynamics and matrix degradation / Taylor W. Starnes, Christa L. Cortesio, and Anna Huttenlocher -- Endothelial cell migration under flow / Beata Wojciak-Stothard -- In vitro analysis of chemotactic leukocyte migration in 3D environments / Michael Sixt and Tim Lammermann -- Quantification of transendothelial migration using three-dimensional confocal microscopy / Robert J. Cain, Barbara Borda d'Agua, and Anne J. Ridley -- Chemotaxis of slow migrating mammalian cells analysed by video microscopy / Roman Zantl and Elias Horn -- Live cell fluorescence microscopy techniques / Shawn A. Galdeen and Alison J. North -- Measuring invasion in an organotypic model / Veronika Jenei, Maria L. Nystrom, and Gareth J. Thomas -- Analysis of cell migration using Caenorhabditis elegans as a model system / Ming-Ching Wong, Maria Martynovsky, and Jean E. Schwarzbauer -- Drosophila hemocyte migration : an in vivo assay for directional cell migration / Carolina G.A. Moreira [and others] -- Measuring inflammatory cell migration in the zebrafish / Philip M. Elks, Catherine A. Loynes, and Stephen A. Renshaw -- Border cell migration : a model system for live imaging and genetic analysis of collective cell movement / Mohit Prasad [and others] -- Assessment of development and chemotaxis in Dictyostelium discoideum mutants / Yulia Artemenko, Kristen F. Swaney, and Peter N. Devreotes -- Simple experimental and spontaneous metastasis assays in mice / Gary M. Box and Suzanne A. Eccles -- Two-photon intravital multicolour imaging to study metastatic behaviour of cancer cells in vivo / Sylvia E. Le Devedec [and others] -- Measuring angiogenesis in mice / Bernardo Tavora [and others] -- Time-lapse imaging of chick cardiac precursor cells / Junfang Song, Qiaoyun Yue, and Andrea Munsterberg -- Characterizing system performance in total internal reflection fluorescence microscopy / Juliane P. Schwarz, Ireen Konig, and Kurt I. Anderson -- Fluorescence recovery after photobleaching / Alex Carisey [and others] -- Measuring FRET using time-resolved FLIM / Penny E. Morton and Maddy Parsons -- Cell migration in confinement : a micro-channel-based assay / Melina L. Heuze [and others] -- Functional screening with a live cell imaging-based random cell migration assay / Wies van Roosmalen [and others] -- Beads on the run : beads as alternative tools for chemotaxis assays / Eric Theveneau and Roberto Mayor.
  • 2010 Karger
    volume editors, Frank Entschladen, Kurt S. Zänker.
    The migrating cell / Entschladen, F., Zänker, K.S. -- Stem cell migration in health and disease / Dittmar, T. ... [et al.] -- Leukocyte motility and human disease / Cooper, K., Nuzzi, P., Huttenlocher, A. -- Coordination of leukocyte polarity and migration / Martín-Cófreces, N.B., Serrador, J.M., Sánchez-Madrid, F. -- Positioning phosphoinositide 3-kinase in chemokine and antigen-dependent T-lymphocyte navigation mechanisms / Ward, S.G. -- Migration of functionally specialized T-helper cells : TFH cells, Th17 cells, and FoxP3+ T cells / Kim, C.H. -- ADAMs and ectodomain proteolytic shedding in leukocyte and tumour cell migration / Ager, A., Knäuper, V., Poghosyan, Z. -- Guided tour of cell migration : signals and pathways / Ratke, J., Lang, K. -- Regulation of the E-cadherin adhesion complex in tumor cell migration and invasion / Menke, A., Giehl, K. -- The cytoskeletal connection : understanding adaptor proteins / Ziegler, W.H. -- Locomotor force generation by myosins / Jbireal, J.M.A., Entschladen, F., Zänker, K.S.
  • 2006 Springer
    edited by Alan Wells.
    Cancer Morbidity and mortality result from invasive and metastatic spread. Advances in the field have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book presents an overview of these studies.
  • 2012 ScienceDirect
    [edited by] Nicholas Sperelakis.
    Sect. I. Biophysical chemistry, metabolism, second messengers, and ultrastructure. Biophysical chemistry of physiological solutions / Jeffrey c. Freedman -- Physiological structure and function of proteins / Matthew R. Pincus -- Cell membranes / Jeffrey C. Freedman -- Ionophores in planar lipid bilayers / Jeffrey C. Freedman -- Cell structure / Michael S. Forbes -- Signal transduction and second messengers / Aldebaran M. Hofer -- Calcium as an intracellular second messenger: mediation by calcium-binding proteins / John R. Dedman and Marcia A. Kaetzel -- Sect. II. Membrane potential, transport physiology, pumps, and exchangers. Diffusion and permeability / Nicholas Sperelakis and Jeffrey C. Freedman -- Origin of resting membrane potentials / Nicholas Sperelakis -- Gibbs-Donnan equilibrium potentials / Nicholas Sperelakis -- Mechanisms of carrier-mediated transport: facilitated diffusion, cotransport and countertransport / Steven M. Grassl -- Active ion transport by ATP-driven ion pumps / Robert A. Farley -- Ca2+ -ATPases / Tracy J. Pritchard, Istvan Edes and Evangelia G. Kranias -- Na+ -Ca2+ exchange currents / John H.B. Bridge, Natalia S. Torres and Michela Ottolia -- Intracellular chloride regulation / Francisco J. Alvarez-Leefmans -- Osmosis and regulation of cell volume / Clive M. Baumgarten and Joseph J. Feher -- Intracellular pH regulation / Robert W. Putnam -- Sect. III. Membrane excitability and ion channels. Cable properties and propagation of action potentials / Nicholas sperelakis -- Electrogenesis of membrane excitability / Nicholas Sperelakis -- Patch-clamp techniques / Laura Conforti -- Structure and mechanism of voltage-gated ion channels / Simon Rock Levinson and William A. Sather -- Biology of gap junctions / Richard D. Veenstra -- Regulation of cardiac ion channels by cyclic nucleotide-dependent phosphorylation / Gordon M. Wahler and Nicholas Sperelakis -- Direct regulation of ion channels by GTP-binding proteins / Atsushi Inanobe and Yoshihisa Kurachi -- Developmental changes in ion channels / Takeshi Kobayashi ... [et al.] -- Regulation of ion channel localization and activity through interactions with the cytoskeleton / Stephen Lambert -- Why are so many ion channels mechanosensitives? / Catherine E. Morris -- Sect. IV. Ion channels as targets for toxins, drugs, and genetic diseases. Ion channels as targets for toxins / Kenneth M. Blumenthal -- Ion channels as targets for drugs / Seth Robey, Kevin J. Sampson and Robert S. Kass -- Inherited diseases of ion transport / Robert A. Farley -- Sect. V. Synaptic transmission and sensory transduction. Ligand-gated ion channels / Kenneth R. Tovar and Gary L. Westbrook -- Synaptic transmission / Janusz B. Suszkiw -- Excitation-secretion coupling / Nicole Gallo-Payet and Marcel Daniel Payet -- Stimulus-response coupling in metabolic sensor cells / Stan Misler -- Cyclic nucleotide-gated ion channels / Anita L. Zimmerman -- Sensory receptors and mechanotransduction / Andrew S. French and Päivi H. Torkkeli -- Acoustic transduction / Daniel C. Marcus -- Visual transduction / Anita L. Zimmerman -- Gustatory and olfactory sensory transduction / Stephen D. Roper -- Infrared sensory organs / Stephen D. Roper and Michael S. Grace -- Electroreceptors and magnetoreceptors / Timothy C. Tricas and Bruce A. Carlson -- Sect. VI. Muscle and other contractile systems. Skeletal muscle excitability / Nicholas Sperelakis, Judith Heiny and Hugo gonzalez-Serratos -- Cardiac action potentials / Gordon M. Wahler -- Smooth muscle excitability / Neil D. Detweiler ... [et al.] -- Excitation-contraction coupling in skeletal muscle / Judith A. Heiny and Gerhard Meissner -- Contraction of muscles: mechanochemistry / Richard J. Paul -- Flagella, cilia, actin- and centrin-based movement / Kenneth W. Foster -- Electrocytes of electric fish / Anthony L. Gotter, Marcia A. Kaetzel and John R. Dedman -- Sect. VII. Protozoa and bacteria. Physiological adaptations of protists / Michael Levandowsky -- Physiology of prokaryotic cells / Dennis W. Grogan -- Sect. VIII. Specialized processes: photosynthesis and bioluminescence. Photosynthesis / Darrell Fleischman -- bioluminescence / J. Woodland Hastings.
  • 2013 Springer Protocols
    edited by Lorenzo Galluzzi [and others].
    Cell senescence as both a dynamic and a static phenotype / Andrew R.J. Young, Masako Narita, and Masashi Narita -- Senescence regulation by mTOR / Vjekoslav Dulic -- Senescence regulation by the p53 protein family / Yingjuan Qian and Xinbin Chen -- Markers of cellular senescence / Amancio Carnero -- Biomarkers of cell senescence assessed by imaging cytometry / Hong Zhao and Zbigniew Darzynkiewicz -- Cytofluorometric assessment of cell cycle progression / Ilio Vitale, Mohamed Jemaà, Lorenzo Galluzzi, Didier Metivier, Maria Castedo, and Guido Kroemer -- Quantification of cell cycle-arresting proteins / Oliver Kepp, Isabelle Martins, Laurie Menger, Mickaël Michaud, Sandy Adjemian, Abdul Qader Sukkurwala, Lorenzo Galluzzi, and Guido Kroemer -- Colorimetric detection of senescence-associated [beta] galactosidase / Koji Itahana, Yoko Itahana, and Goberdhan P. Dimri -- Chemiluminescent detection of senescence-associated [beta] galactosidase / Vinicius Bassaneze, Ayumi Aurea Miyakawa, and José Eduardo Krieger -- Detection of the senescence-associated secretory phenotype (SASP) / Francis Rodier -- Unbiased characterization of the senescence-associated secretome using SILAC-based quantitative proteomics / Juan Carlos Acosta, Ambrosius P. Snijders, and Jesús Gil -- Detection of senescence-associated heterochromatin foci (SAHF) / Katherine M. Aird and Rugang Zhang -- Monitoring DNA damage during cell senescence / Glyn Nelson and Thomas von Zglinicki -- Assessment and quantification of telomerase enzyme activity / Michelle F. Maritz, Laura A. Richards, and Karen L. MacKenzie -- Methods for the assessment of telomere status / Asako J. Nakamura -- Detection of nuclear envelope alterations in senescence / Clea Bárcena, Fernando G. Osorio, and José Maria Pérez Freije -- Measuring reactive oxygen species in senescent cells / João F. Passos, Satomi Miwa, and Thomas von Zglinicki -- Quantification of protein carbonylation / Nancy B. Wehr and Rodney L. Levine -- Assays for the measurement of lipid peroxidation / Ana Cipak Gasparovic, Morana Jaganjac, Branka Mihaljevic, Suzana Borovic Sunjic, and Neven Zarkovic -- Raman spectroscopy for the detection of AGEs/ALEs / J. Renwick Beattie, John J. McGarvey, and Alan W. Stitt -- Monitoring oncogenic B-RAF-induced senescence in melanocytes / Sieu L. Tran and Helen Rizos -- Methods to investigate the role of SIRT1 in endothelial senescence / Bo Bai and Yu Wang -- Monitoring nutrient signaling through the longevity protein p66SHC1 / Sofia Chiatamone Ranieri and Giovambattista Pani -- Profiling the metabolic signature of senescence / Florian M. Geier, Silke Fuchs, Gabriel Valbuena, Armand M. Leroi, and Jacob G. Bundy -- Genome-wide RNAi screening to identify regulators of oncogene-induced cellular senescence / Narendra Wajapeyee, Sara K. Deibler, and Michael R. Green -- Integrated approach for monitoring cell senescence / Tatiana V. Pospelova, Zhanna V. Chitikova, and Valery A. Pospelov -- Robust multiparametric assessment of cellular senescence / Clara Correia-Melo, Diana Jurk, and João F. Passos -- Assessing chronological aging in bacteria / Stavros Gonidakis and Valter D. Longo -- Assessing organismal aging in the filamentous fungus Podospora anserina / Heinz D. Osiewacz, Andrea Hamann, and Sandra Zintel -- Assessing chronological aging in Saccharomyces cerevisiae / Jia Hu, Min Wei, Mario G. Mirisola, and Valter D. Longo -- Assessing aging and senescent decline in Caenorhabditis elegans : cohort survival analysis / Eirini Lionaki and Nektarios Tavernarakis -- High-throughput and longitudinal analysis of aging and senescent decline in Caenorhabditis elegans / Eirini Lionaki and Nektarios Tavernarakis -- Assessing senescence in Drosophila using video tracking / Reza Ardekani, Simon Tavaré, and John Tower -- Assessing vascular senescence in zebrafish / Sandra Donnini, Antonio Giachetti, and Marina Ziche.
  • 1982-
    edited by Thomas G. Pretlow, Theresa P. Pretlow ; contributors, A.M. Cheret ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2012 Springer
    Malay Chatterjee, Khosrow Kashfi, editors.
    1. GRB2 Signaling as a Molecular Target for Cancer / Alessio Giubellino -- 2. Human Arylamine N-acetyltransferase 1: From Drug Metabolism to Drug Target / Fernando Rodrigues-Lima, Julien Dairou, Florent Busi, and Jean-Marie Dupret -- 3. Targeting Argininosuccinate Synthetase in Cancer Therapy / Niramol Savaraj, Min You, Chunjing Wu, Macus Tien Kuo, Vy Dinh, Medhi Wangpaichitr, and Lynn Feun -- 4. Parathyroid Hormone-Related Peptide Signaling in Cancer / Franco Oreste Ranelletti and Giovanni Monego -- 5. Signalling Molecules as Selective Targets for Therapeutic Strategies in Multiple Myeloma / Francesco Piazza and Gianpietro Semenzato -- 6. Role of Bile Acids in Carcinogenesis of Gastrointestinal Tract / Hiroshi Yasuda and Fumio Itoh -- 7. AIB1: A Transcriptional Coactivator Which Integrates Signaling Cross Talk in Cancer Cells / Macarena Ferrero and Jaime Font de Mora -- 8. Rational Design of DNA Anticancer Agent That Targets Signal Transducer and Activator of Transcription 3 (Stat3) for Cancer Therapy / Naijie Jing -- 9. Estrogen Receptor Signaling in Lung Cancer / P.A. Hershberger and J.M. Siegfried -- 10. Microparticle Dissemination of Biological Activities: Implications for Cancer Biology / Pauline P. Goh -- 11. Protein Kinase D Signaling in Cancer / Peter Storz -- 12. Cell Signaling and Cancer: Integrated, Fundamental Approach Involving Electron Transfer, Reactive Oxygen Species, and Antioxidants / Peter Kovacic and Ratnasamy Somanathan -- 13. Targeting Signal Transducer and Activator of Transcription (STAT) for Anticancer Therapy / Fabio P.S. Santos, Inbal Hazan-Halevy, and Zeev Estrov.
  • 2015 Springer
    Henry J. Leese, Daniel R. Brison, editors.
    The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.
    Also available: Print – 2015
  • 2005 Springer
    edited by Jahar Bhattacharya.
    Heme oxygenase-1 and carbon monoxide in vascular regulation / Stefan W. Ryter and Augustine M.K. Choi -- Tumor necrosis factor-[alpha]/receptor signaling through the Akt kinase / Osman Nidai Ozes ... [et al.] -- Protein modifications by nitric oxide and reactive nitrogen species / Harry Ischiropoulos -- Redox signaling in hypoxic pulmonary vasoconstriction / E. Kenneth Weir ... [et al.] -- cGMP-dependent protein kinase in regulation of the perinatal pulmonary circulation / Usha Raj ... [et al.] -- Glutamate receptor activation in the pathogenesis of acute leg injury / Sami I. Said -- Carboxyl methylation of small GTPases and endothelial cell function / Sharon Rounds, Elizabeth O. Harrington, and Qing Lu -- Pressure-induced inflammatory signaling in lung endothelial cells / Wolfgang M. Kuebler -- Regulation of endothelial barrier function: contributions of the transcellular and paracellular pathways / Dolly Mehta, Richard D. Minshall, and Asrar B. Malik -- Sphingolipid signaling: implications for vascular biology / Margaret M. Harnett -- Regulations of cytokine signaling / Bao Q. Vuong ... [et al.] -- Cell signaling by vasoactive agents / Barry L. Fanburg ... [et al.] -- Reactive oxygen species and cell signaling in lung ischemia / Aron B. Fisher -- Pulmonary vascular barrier regulation by thrombin and Edg receptors / Jeffrey R. Jacobson and Joe G.N. Garcia -- Second-messenger signaling in lung capillaries / Kaushik Parthasarathi -- Plasma membrane-to-nucleus calcium signaling / Giles E. Hardingham -- Signaling by mitochondria / Navdeep S. Chandel -- Pro-inflammatory signaling by endothelial focal complexes in lung / Sunita Bhattacharya -- Hydrogen peroxide as intracellular messenger: production, target, and elimination / Sue Goo Rhee ... [et al.] -- Calcium-inhibited adenylyl cyclase (AC6) controls endothelial cell barrier function / Troy Stevens.
  • 2011 Springer
    Yasushi Sako, Masahiro Ueda, editors.
  • 2007 Springer
    edited by Stuart K. Calderwood.
    Surveys the knowledge concerning the expression and function of stress proteins in different organisms, ranging from prokaryotes to humans. This book provides an overview of the diversity and complex evolutionary history of cell stress proteins and describes their function and expression in different eukaryote models.
  • 2012
    Weizhe Hong.
    Neurons are interconnected with extraordinary precision to allow proper propagation and integration of neural activities. The organization of these specific connections emerges from sequential developmental events, including axon guidance, target selection, and synapse formation. Compared to axon guidance, little is known about how selection and matching between pre- and post-synaptic partners are achieved. To ensure the proper relay of olfactory information in flies, axons of ~50 classes of olfactory receptor neurons (ORNs) form one-to-one connections with dendrites of ~50 classes of projection neurons (PNs). Previous developmental analysis has shown that PN dendrites first target to specific areas within the developing antennal lobe to create a proto-map. This is followed by ORN axon invasion into the antennal lobe. However, it is unclear (1) how PNs target their dendrites to specific areas and (2) how ORN axons subsequently recognize PN dendrites to form highly specific one-to-one connections. To address the first question, I conducted a genetic screen to identify new genes involved in PN dendrite targeting. I identified Capricious, a leucine-rich repeat transmembrane protein that is differentially expressed in different PN classes. Loss- and gain-of-function studies indicate that Capricious instructs the segregation of Capricious-positive and negative PN dendrites to discrete glomerular targets. Moreover, the function of Capricious in regulating PN dendrite targeting is independent of pre-synaptic ORNs. The closely related protein Tartan plays a partially redundant function with Capricious. Therefore, these leucine-rich repeat proteins instruct targeting of PN dendrites to discrete glomeruli in the antennal lobe. To address the second question, we designed highly sensitive and robust assays to examine the matching and mismatching between PNs and ORNs. This allowed me to perform two unbiased screens, which independently identified two Teneurins, Ten-m and Ten-a, as synaptic matching molecules. Teneurins are EGF repeat-containing transmembrane proteins that are evolutionarily conserved from worms to mammals. Drosophila Teneurins, Ten-m and Ten-a, are highly expressed in select PN and ORN matching pairs. Loss- and gain-of-function of Teneurins cause specific mismatching of ORN axons and PN dendrites. Moreover, Teneurins promote homophilic interactions in vitro, and homophilically mediate trans-cellular interactions to promote PN-ORN attraction in vivo. Therefore, I propose that Teneurins instruct synaptic matching specificity between PNs and ORNs through homophilic attraction. The identification of Teneurins reveals a general mechanism for determining synapse specificity directly between pre- and post-synaptic neurons. In summary, I have identified two major mechanisms for the stepwise assembly of the olfactory circuit. In the first step, PN dendrites target to specific, discrete glomerular locations in the antennal lobe through a pair of leucine-rich repeat transmembrane proteins, Capricious and Tartan. Subsequently, ORN axons arrive at the antennal lobe, and recognize PN dendrites through homophilic attractions mediated by a pair of EGF repeat-containing transmembrane proteins, Ten-m and Ten-a. These molecules and underlying mechanisms not only help mechanistically understand the olfactory circuit assembly but also elucidate the general principles by which wiring specificity is established.
  • 2005 Springer
    by Lee E. Limbird.
    Also available: Print – 2005
  • 2009 Springer
    Adrian Gee, editor.
    Part 1. Regulatory. -- Regulation of Cell Product Manufacturing and Delivery: A United States Perspective / R.W. Lindblad -- The Regulatory Situation for Academic Cell Therapy Facilities in Europe / I. Slaper-Cortenbach, M. Scott, D. Herrmann, M. Introna and K. Theunissen, et al. -- A Regulatory System for Cell and Tissue Therapies: Proposed Approach in Australia / A. Farrugia -- Part 2. GMP Facility Design. -- University of Minnesota - Molecular and Cellular Therapeutics (MCT) / D.H. McKenna -- University of Pittsburgh Cancer Institute - Hematopoietic Stem Cell Laboratory (HSC Lab)/Immunological Monitoring and Cellular Products Laboratory (IMCPL) / D.L. Griffin, A.D. Donnenberg and T.L. Whiteside / Baylor College of Medicine - Center for Cell and Gene Therapy (CAGT) / A. Gee -- Design of a New GMP Facility - Lessons Learned / A. Gee -- Part 3. Professional Cell Therapy Standards. -- AABB Cell Therapy Standards / Z.M. Szczepiorkowski and E. Nunes -- Professional Standards for Cellular Therapies: Foundation for the Accreditation of Cellular Therapy (FACT) / P.I. Warkentin -- Part 4. Facility Operations -- Standard Operating Procedures / C.G. Lindgren -- Staffing, Training, and Competency / D.M. Kadidlo -- Cleaning Procedures / A. Gee and D.L. Lyon -- Environmental Monitoring / A. Gee and D.L. Lyon -- Supply Management / A. Gee and C.M. Rooney -- Facility Equipment / D.L. Griffin -- Quality / J.W. Atkins -- Product Manufacturing / A. Gee -- Product Review, Release, and Administration / N.H. Collins -- Use of a Facility Master File to Facilitate Regulatory Submissions for Cell Therapy Products / E.J. Read and H.M. Khuu.
  • 2006 Springer
    edited by Cyndy Davis Sanberg and Paul R. Sanberg.
    Current views of the embryonic and neural stem cell : cell replacement or molecular repair? / Roya Sabetrasekh ... [et al.] -- Developing novel cell sources for transplantation in Parkinson's disease / Nicolaj S. Christophersen ... [et al.] -- Neural transplantation in the nonhuman primate model of Parkinson's disease / Kimberly B. Bjugstad and John R. Sladek, Jr. -- Cell-based therapy for Huntington's disease / Claire M. Kelly, Stephen B. Dunnett, and Anne E. Rosser -- Use of bone marrow stem cells as therapy for behavioral deficits in rodent models of Huntington's disease / Gary L. Dunbar, Justin D. Oh-Lee, and Laurent Lescaudron -- Human neuroteratocarcinoma cells as a neural progenitor graft source for cell transplantation in stroke / Cesario V. Borlongan ... [et al.] -- Therapeutic applications of bone marrow-derived stem cells in neurologic injury and disease / C. Dirk Keene ... [et al.] -- Cell therapy for models of pain and traumatic brain injury / Mary Eaton and Jacqueline Sagen -- The use of sertoli cells in neural transplantation / Dwaine F. Emerich, Cesario V. Borlongan, and Craig Halberstadt -- The choroids plexus : a novel graft source for neural transplantation / Cesario V. Borlongan ... [et al.] -- Progress and challenges in immunoisolation for CNS cell therapy / Christopher G. Thanos and Dwaine F. Emerich -- Evidence-based methodology for advancing neural reconstruction / Stephen Polgar -- Hematopoietic cell therapy for brain repair / Martina Vendrame and Alison E. Willing -- Stem cells and regenerative medicine : commercial and pharmaceutical implications / L. Eduardo Cruz and Silvia P. Azevedo.
    Also available: Print – 2006
  • 2006 HighWire
    edited by Tomasz Siminiak.
  • 2011 Springer Protocols
    edited by Ella Palmer.
    Cell-Based Microarrays: Overview / Ella Palmer -- Cell-Based Co-transfection Microarrays for Use with HEK293T Cells on a Poly d-Lysine-Coated Polystyrene Microplate / Meenal Soni, Fang Lai -- Large-Scale Cell-Based Microarrays and Their Use with HEK293T Cells and Downstream Apoptotic Assays / Ella Palmer, Tom C. Freeman -- A Novel Fluorescent Transcriptional Reporter for Cell-Based Microarray Assays / Tanya M. Redmond, Michael D. Uhler -- High-Throughput Subcellular Protein Localization Using Transfected-Cell Arrays: Subcellular Protein Localization Using Cell Arrays / Yuhui Hu, Michal Janitz -- Cell Arrays for the Measurement of Organelle Dynamics in Living Cells / Holger Erfle, Tautvydas Lisauskas, Christoph Claas, Jürgen Reymann, Vytaute Starkuviene -- High-Throughput Immunofluorescence Microscopy Using Yeast Spheroplast Cell-Based Microarrays / Wei Niu, G. Traver Hart, Edward M. Marcotte -- Cell-Based Microarrays of Infectious Adenovirus Encoding Short Hairpin RNA (shRNA) / Hansjürgen Volkmer, Frank Weise -- Reverse Transfected Cell Microarrays in Infectious Disease Research / Andreas Konrad, Ramona Jochmann, Elisabeth Kuhn, Elisabeth Naschberger, Priya Chudasama, Michael Stürzl -- Transfected Cell Microarrays for the Expression of Membrane-Displayed Single-Chain Antibodies / Baochuan Lin, James B. Delehanty -- Blood Cell Capture on Antibody Microarrays and Monitoring of the Cell Capture Using Surface Plasmon Resonance Imaging / Yoann Roupioz, Sarah Milgram, André Roget, Thierry Livache -- Immobilized Culture and Transfection Microarray of Non-adherent Cells / Satoshi Yamaguchi, Erika Matsunuma, Teruyuki Nagamune -- Plasma Polymer and PEG-Based Coatings for DNA, Protein and Cell Microarrays / Andrew L. Hook, Nicolas H. Voelcker, Helmut Thissen -- Polymer Microarrays for Cellular High-Content Screening / Salvatore Pernagallo, Juan J. Diaz-Mochon -- High-Throughput Analyses of Gene Functions on a Cell Chip by Electroporation / Koichi Kato, Hiroo Iwata -- Microfluidic Image Cytometry / Ken-ichiro Kamei, Jing Sun, Hsian-Rong Tseng, Robert Damoiseaux.
  • 2013 Springer
    Jukka Jolkkonen, Piotr Walczak, editors.
    Stroke remains one of the main causes of death and disability worldwide. Effective therapy for stroke recovery remains an unmet need. Much hope and promises are placed on cell-based therapies. The aim of this book is to provide focused yet comprehensive reviews on the current state of cell-based approaches in the treatment of stroke. The topics covered include experimental data on functional outcome after intravascular and intracerebral delivery of cells in stroke animals, followed by translational chapters which will rely heavily on the use of different imaging modalities in the tracking of cells. The last and most challenging part will describe the early phase of clinical studies, providing guidelines for future research and clinical applications. Clearly and concisely written, this text will be a useful resource for neurologists, radiologists, and neuroscientists interested in cell transplantation as a therapeutic strategy for stroke patients.
  • 2014 Karger
    volume editors, Ricardo P. Casaroli-Marano, Marco A. Zarbin.
    Age-related macular degeneration: clinical findings, histopathology, and imaging techniques / Zarbin, M.A.; Casaroli-Marano, R.P.; Rosenfeld, P.J. -- General pathophysiology in retinal degeneration / Wert, K.J.; Lin, J.H.; Tsang, S.H. -- Juvenile-onset macular degeneration and allied disorders / North, V.; Gelman, R.; Tsang, S.H. -- Diagnosis and complementary examinations / Menghini, M.; Duncan, J.L. -- Stem cells for retinal repair / Stern, J.; Temple, S. -- Differentiation of pluripotent stem cells into retinal pigmented epithelium / Croze, R.H.; Clegg, D.O. -- Neural retinal regeneration with pluripotent stem cells / Ramsden, C.M.; Powner, M.B.; Carr, A.-J.F.; Smart, M.J.K.; da Cruz, L.; Coffey, P.J. -- Stem cells, retinal ganglion cells and glaucoma / Sluch, V.M.; Zack, D.J. -- Stem cells : immunology and immunomodulation / Tena, A.; Sachs, D.H. -- Biochemical restoration of aged human Bruch's membrane : experimental studies to improve retinal pigment epithelium transplant survival and differentiation / Sugino, I.K.; Sun, Q.; Cheewatrakoolpong, N.; Malcuit, C.; Zarbin, M.A. -- Approaches to cell delivery : substrates and scaffolds for cell therapy / Kundu, J.; Michaelson, A.; Baranov, P.; Young, M.J.; Carrier, R.L. -- Microdevice-based cell therapy for age-related macular degeneration / Lu, B.; Tai, Y.-C.; Humayun, M.S. -- Cell and gene therapy / Rao, R.C.; Zacks, D.N. -- Cellular manufacturing for clinical applications / Sheu, J.; Klassen, H.; Bauer, G. -- Regulatory issues in cell-based therapy for clinical purposes / Casaroli-Marano, R.P.; Tabera, J.; Vilarrodona, A.; Trias, E.
  • 2006. Springer
    [edited by] Frantisek Baluska, Dieter Volkmann, Peter W. Barlow.
    Cell-cell channels and their implications for cell theory / Frantisek Baluska, Dieter Volkmann, and Peter W. Barlow -- Mating cell-cell channels in conjugating bacteria / Elisabeth Grohmann -- The tetrahymena conjugation junction / Eric S. Cole -- Cytoplasmic bridges in volvox and its relatives / Harold J. Hoops, Ichiro Nishii, and David L. Kirk -- Vegetative hyphal fusion in filamentous fungi / Nick D. Read and M. Gabriela Roca -- Plasmodesmata: cell-cell channels in plants / Yoselin Benitez Alfonso, Laurence Cantrill, and David Jackson -- Sieve-pore plugging mechanisms / Aart J.E. van Bel -- Actin and myosin VIII in plant cell-cell channels / Jozef Samaj ... [et al.] -- Cell-cell communication in wood / John R. Barnett -- TMV movement protein targets cell-cell channels in plants and prokaryotes: possible roles of tubulin- and FtsZ-based cytoskeletons / Manfred Heinlein -- Viral movement proteins induce tubule formation in plant and insect cells / Jan W.M. van Lent and Corinne Schmitt-Keichinger -- Cell-cell movements of transcription factors in plants / Alexis Maizel -- Gap junctions: cell-cell channels in animals / Fabio Mammano -- Tunneling nanotubes: membranous channels between animal cells / Hans-Hermann Gerdes and Amin Rustom -- Cytoplasmic bridges as cell-cell channels of germ cells / Sami Ventelä -- Fusome as a cell-cell communication channel of drosophila ovarian cyst / Jean-René Huynh -- Cytonemes as cell-cell channels in human blood cells / Svetlana Ivanovna Galkina .. [et al.] -- Paracellular pores in endothelial barriers / Luca Manzi and Gianfranco Bazzoni -- Channels across endothelial cells / Radu V. Stan -- Molecular transfers through transient lymphoid cell-cell channels / Mary Poupot, Julie Gertner, and Jean-Jacques Fournié -- Cell-cell transport of homeoproteins: with or without channels / Alain Joliot and Alain Prochiantz -- Virological synapse for cell-cell spread of viruses / Eduardo Garcia and Vincent Piguet -- Cell-cell fusion: transient channels leading to plasma membrane merger / William A. Mohler.
  • 2013 Springer Protocols
    edited by Troy A. Baudino.
    Proteomics analysis of contact-initiated eph receptor-ephrin signaling / Claus Jorgensen and Alexei Poliakov -- Control of vascular tube morphogenesis and maturation in 3D extracellular matrices by endothelial cells and pericytes / George E. Davis ... [and 8 others] -- Analyzing cell-cell interactions in 3-dimensional adhesion assays / Stephanie L.K. Bowers and Troy A. Baudino -- Production of spontaneously beating neonatal rat heart tissue for calcium and contractile studies / Fnu Gerilechaogetu ... [and 6 others] -- Paracrine communication between mechanically stretched myocytes and fibroblasts / Hao Feng ... [and 6 others] -- Assessing blood-brain barrier function using in vitro assays / Joseph Bressler, Katherine Clark, and Cliona O'Driscoll -- Methods to assess tissue permeability / Juan C. Ibla and Joseph Khoury -- In vivo quantification of metastatic tumor cell adhesion in the pulmonary microvasculature / F. Bartsch ... [and 4 others] -- Cell membrane vesicles as a tool for the study of direct epithelial-stromal interaction: lessons from CD147 / Eric Gabison ... [and 3 others] -- Microencapsulation of stem cells to study cellular interactions / Keith Moore, Adam Vandergriff, and Jay D. Potts -- Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies / Timothy N. Feinstein -- Single cell analysis of lipid rafts / William T. Lee -- Micropatterning cell adhesion on polyacrylamide hydrogels / Jian Zhang ... [and 3 others] -- Measuring cell-cell tugging forces using bowtie-patterned mPADs (microarray post detectors) / Daniel M. Cohen, Mike T. Yang, and Christopher S. Chen -- Generation and analysis of biosensors to measure mechanical forces within cells / Katharina Austen ... [and 4 others] -- Proteomic analysis of the left ventricle post-myocardial infarction to identify in vivo candidate matrix metalloproteinase substrates / Andriy Yabluchanskiy ... [and 5 others].
  • 2006 Springer Protocols
    edited by Sean P. Colgan.
    Analysis of mammallian sperm-egg membrane interactions during in vitro fertilization / Genevieve B. Wortzman, Allison J. Gardner, and Janice P. Evans -- Collagen gel contraction assay / Peter Ngo ... [et al.] -- Methods to assess tissue permeability / Juan C. Ibla and Joseph Khoury -- Bacterial-bacterial cell interactions in biofilms: detection of polysaccharide intercellular adhesins by blotting and confocal microscopy / Kimberly K. Jefferson and Nuno Cerca -- A biochemical method for tracking cholera toxin transport from plasma membrane to golgi and endoplasmic reticulum / Heidi E. DeLuca and Wayne I. Lencer -- Isolation and culture of murine heart and lung endothelial cells for in vitro model systems / Yaw-Chyn Lim and Frances W. Luscinskas -- Blood-brain barrier and cell-cell interactions: methods for establishing in vitro models of the blood/brain barrier and transport measurements / Michael Aschner ... [et al.] -- Interactions of intestinal epithelial cells with bacteria and immune cells: methods to characterize microflora and functional consequences / Geraldine Canny, Alexander Swidsinski, and Beth A. McCormick -- Expression cloning of signaling proteins regulated by cell adhesion / Michelle L. Matter and Joe W. Ramos -- Assays for the calcium sensitivity of desmosomes / Anita J. Merritt, Anthea Scothern, and Tanusree Bhattacharyya -- Tight junctions and cell-cell interactions / Markus Utech, Matthias Brüwer, and Asma Nusrat -- Simultaneous immunofluorescence detection of cadherin and [beta]-catenin in mouse tissue sections / Nobuko Obara -- In vitro neutrophil transepithelial migration / Winston Y. Lee ... [et al.] -- The blot running assay: a method for identifying adhesion molecules mediating binding under shear conditions / Robert Sackstein and Robert Fuhlbrigge -- Cell-cell interaction in the transcellular biosynthesis of novel [omega]-3-derived lipid mediators / Nan Chiang and Charles N. Serhan -- Isolation and analysis of lipid rafts in cell-cell interactions / Aimee Landry and Ramnik Xavier. The role of junctional adhesion molecules in interactions between vascular cells / Triantafyllos Chavakis and Valeria Orlova -- Cell-cell interactions on solid matrices / Nancy A. Louis, Dionne Daniels, and Sean P. Colgan -- Cell-cell interactions in the kidney: inducible expression of mutant G protein [alpha]-subunits in madin-darby cannine kidney cells for studies of epithelial cell junction structure and function / Ernesto Sabath and Bradley M. Denker -- Nucleotide metabolism and cell-cell interactions / Holger K. Eltzschig ... [et al.] --
  • 2005 Springer
    Agata Copani, Ferdinando Nicoletti and I.N.M. Neuromed.
    Cell cycle activation in neurons: the final exit of brain-morpho-dysregulation / Thomas Arendt -- Paved with good intentions: the link between cell cycle and cell death in the mammalian central nervous system / Yan Yang and Karl Herrup -- The role of presenilins in the cell cycle and apoptosis / Mervyn J. Monteiro -- Cell cycle activation and cell death in the nervous system / Zsuzsanna Nagy -- Cell cycle and chromosome segregation defects in Alzheimer's disease / Huntington Potter -- Alzheimer disease-a new beginning or a final exit? / Mark E. Obrenovich ... [et al.] -- From cell cycle activation to the inhibition of the WNT pathway: a hypothesis of how neurons die in response to B-Amyloid / Agata Copani ... [et al.].
  • 2010 Springer
    Roy Zent, Ambra Pozzi, editors.
  • 2010
    Bertrand Howyen Lui.
    Protein-protein interactions such as ligand-receptor interactions mediate cell signaling and can be used to control and modulate cell behavior. Despite their effectiveness in natural settings, protein ligands require optimization of properties such as homogeneity, lack of immunogenicity, potency, or stability to be used in therapeutic applications. Multiple combinatorial and rational protein engineering techniques have been developed to improve therapeutic proteins. However, these methods have been limited by the lack of a robust, high-throughput system for the expression of complex mammalian proteins. In this dissertation, cell-free protein synthesis (CFPS) was applied to fill this void, and the potential of this approach was demonstrated with epidermal growth factor (EGF). EGF binds to the EGF receptor (EGFR) and stimulates cell proliferation, migration, and differentiation. EGF has been pursued for wound healing and tissue engineering applications, thus EGF mutants with enhanced biochemical and biophysical properties are of great biomedical interest. The primary goal of this thesis research was to create a directed evolution platform to screen protein libraries based on biological function, an objective not feasible with other protein engineering approaches. We developed methods to fully express mutated protein libraries and to determine the efficacy of each individual member by employing a high-throughput protein product assay followed by a cell-based functional assay conducted with uniform dosage. Using this platform, we discovered the first known EGF mutants with enhanced mitogenic activity compared to wild-type EGF despite many previous attempts. These mutants bound EGFR with approximately ten-fold weaker binding affinity than wild-type EGF and reduced depletion of soluble EGF and cell surface EGFR when cells were treated with EGF. Second, we employed CFPS to rapidly characterize an array of EGF mutants and rationally engineered mutants with ideal biochemical properties for EGFR activation. It is important to note that all of these studies can be carried out without the need for protein purification from the CFPS reaction mixture, significantly increasing the number of mutants that can be analyzed. Finally, we site-specifically incorporated non-natural amino acids into EGF by CFPS and demonstrated accessibility by conjugating EGF to polyethylene glycol (PEG), a polymer that has been shown to improve protein retention and stability. These improvements to EGF highlight the advantages of cell-free methods compared to other protein engineering strategies, and advance EGF's potential for therapeutic use. Furthermore, the techniques developed here can be extended to improve the biological efficacy of other clinically-relevant proteins.
  • 2014 Springer Protocols
    edited by Kirill Alexandrov and Wayne A. Johnston.
    Production of eukaryotic cell-free lysate from Leishmania tarentolae / Wayne A. Johnston and Kirill Alexandrov -- Bioinformatics analysis and optimization of cell-free protein synt / Alexander A. Tokmakov ... [et al.] -- Cell-free expression screen to identify fusion tags for improved protein expression / Andrew Kralicek -- One-pot, microscale cell-free enzyme expression and screening / Aarthi Chandrasekaran and Anup K. Singh -- Cell-free translation of biofuel enzymes / Taichi E. Takasuka ... [et al.] -- Cloning-independent expression and screening of enzymes using cell-free protein synthesis systems / Yong-Chan Kwon, Jae-Kwang Song, and Dong-Myung Kim -- High-level cell-free production of membrane proteins with nanodiscs / Christian Roos ... [et al.] -- Cell-free protein-based enzyme discovery and protein-ligand interaction study / Sabrina Guillemer ... [et al.] -- Human cell extract-derived cell-free systems for virus synthesis / Tominari Kobayashi, Kodai Machida, and Hiroaki Imataka -- Cell-free protein synthesis in microfluidic 96-well plates / Kirsten Jackson, Ruba Khnouf, and Z. Hugh Fan -- Preparation of multiple site-specific mutant proteins for NMR studies by PCR-Directed cell-free protein synthesis / Kiyoshi Ozawa and Ruhu Qi -- Site-specific incorporation of unnatural amino acids into proteins by cell-free protein synthesis / Kiyoshi Ozawa and Choy Theng Loh -- In vitro translation of papillomavirus authentic and codon-modified L1 capsid gene mRNAs in mouse keratinocyte cell-free lysate / Kong-Nan Zhao -- Optimized yeast cell-free lysate system for in vitro translation of human virus mRNA / Xiao Wang, Liang Zhao, and Kong-Nan Zhao -- In vitro translation-based protein kinase substrate identification / Szilvia K. Nagy and Tamás Mészáros -- Preparation of protein arrays using cell-free protein expression / Elizabeth A. Cook and Mingyue He -- Posttranscriptional control of protein synthesis in Drosophila S2 cell-free system / Motoaki Wakiyama and Shigeyuki Yokoyama -- Cell-free membrane protein expression / Tomomi Kimura-Soyema, Mikako Shirouzu, and Shigeyuki Yokoyama -- PURE System for Protein Production / Yoshihiro Shimizu ... [et al.] -- Cell-free protein synthesis system from insect cells / Toru Ezure, Takashi Suzuki, and Eiji Ando -- Cell-free expression platform for production of protein microarrays / Xristo Zárate and David W. Galbraith.
  • 2015 Springer Protocols
    edited by Ülo Langel.
    Classes of cell-penetrating peptides / Margus Pooga and Ülo Langel -- Penetratin story : an overview / Edmond Dupont, Alain Prochiantz, and Alain Joliot -- Prediction of cell-penetrating peptides / Mattias Hällbrink and Mati Karelson -- Computer-aided virtual screening and designing of cell- penetrating peptides / Ankur Gautam, Kumardeep Chaudhary, Rahul Kumar, and Gajendra Pal Singh Raghava -- Investigating membrane interactions and structures of CPPs / Fatemeh Madani and Astrid Gräslund -- Determining the effects of membrane-interacting peptides on membrane integrity / William C. Wimley -- Study of CPP mechanisms by mass spectrometry / Sandrine Sagan, Chérine Bechara, and Fabienne Burlina -- Methods to study the role of the glycocalyx in the uptake of cell-penetrating peptides / Samuel Schmidt, Rike Wallbrecher, Toin H. van Kuppevelt, and Roland Brock -- Toxicity, immunogenicity, uptake, and kinetics methods for CPPs / Julia Uusna, Kent Langel, and Ülo Langel -- Unraveling the mechanisms of peptide-mediated delivery of nucleic acids using electron microscopy / Helerin Margus, Carmen Juks, and Margus Pooga -- SCARA involvement in the uptake of nanoparticles formed by cell-penetrating peptides / Henrik Helmfors, Staffan Lindberg, and Ülo Langel -- Protein mimicry and the design of bioactive Cell- penetrating peptides / John Howl and Sarah Jones -- Pepducins and other lipidated peptides as mechanistic probes and therapeutics / Ping Zhang, Lidija Covic, and Athan Kuliopulos -- Identification and characterization of homing peptides using in vivo peptide phage display / Maija Hyvönen and Pirjo Laakkonen -- Antimicrobial and antiviral applications of cell- penetrating peptides / Kalle Pärn, Elo Eriste, and Ülo Langel -- Visualizing actin architectures in cells incubated with cell-penetrating peptides / Lin He, Peter D. Watson, and Arwyn T. Jones -- Cell-penetrating peptides as carriers for transepithelial drug delivery in vitro / Stine Rønholt, Mie Kristensen, and Hanne Mørck Nielsen -- Pathway toward tumor cell-selective CPPs? / Isabel D. Alves, Manon Carré, and Solange Lavielle -- PepFects and nickFects for the intracellular delivery of nucleic acids / Piret Arukuusk, Ly Pärnaste, Mattias Hällbrink, and Ülo Langel -- In vitro assays to assess exon skipping in duchenne muscular dystrophy / Prisca Boisguerin, Liz O'Donovan, Michael J. Gait, and Bernard Lebleu -- Applications of ApoB LDLR-binding domain approach for the development of CNS-penetrating peptides for alzheimer's disease / Eliezer Masliah and Brian Spencer -- CPP-based delivery system for in vivo gene delivery / Kaido Kurrikoff, Kadi-Liis Veiman, and Ülo Langel -- Application of CPPs for brain delivery / Artita Srimanee, Jakob Regberg, and Ülo Langel -- Intracellular delivery of nanoparticles with cell penetrating peptides / Giuseppina Salzano and Vladimir P. Torchilin -- Multifunctional oligoaminoamides for the receptor-specific delivery of therapeutic RNA / Judith Weber, Ulrich Lächelt, and Ernst Wagner -- Cell penetrating peptides for chemical biological studies / Ikuhiko Nakase, Toshihide Takeuchi, and Shiroh Futaki -- Experiences with CPP-based self assembling peptide systems for topical delivery of botulinum toxin / Jane Lee, Phil Kennedy, and Jacob M. Waugh -- Applications of CPPs in genome modulation of plants / Alicja Ziemienowicz, Jordan Pepper, and François Eudes -- DNA transfer into animal cells using stearylated CPP based Transfection Reagent / Kristiina Karro, Tiiu Männik, Andres Männik, and Mart Ustav -- Live cell genomics : cell-specific transcriptome capture in live tissues and cells / Thomas J. Bell and James Eberwine -- Live cell genomics : RNA exon-specific RNA-binding protein isolation / Thomas J. Bell and James Eberwine.
  • 2011 Springer Protocols
    edited by Ülo Langel.
    Classes and prediction of cell-penetrating peptides -- Penetratin story: An overview -- Testing membrane interactions of CPPs -- Interactions of amphipathic CPPs with model membranes -- NMR studies of three-dimensional structure and positioning of CPPs in membrane model systems -- Measurements of the intracellular stability of CPPs -- Tools for predicting binding and insertion of CPPs into lipid bilayers -- Studies of proteoglycan involvement in CPP-mediated delivery -- Uptake kinetics of cell-penetrating peptides -- Thermodynamics of lipid interactions with cell-penetrating peptides -- Calcium and membrane repair -- Mapping of protein transduction pathways with fluorescent microscopy -- Insight into cell-entry mechanisms of CPPs by electron microscopy -- Toxicity methods for CPPs -- Comparison of CPP uptake methods -- Characterization of cellular internalization pathways for CPP-mediated oligonucleotide delivery -- Mimicry of protein function with cell-penetrating peptides -- Homeoprotein intercellular transfer, the hidden face of cell-penetrating peptides -- Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models -- Identification and characterization of tissue-specific protein transduction domains using peptide phage display -- Applications of cell-penetrating peptides as signal transduction modulators for the selective induction of apoptosis -- Splice redirection as a convenient assay to monitor CPP-on efficiency and mechanism -- CPP-directed oligonucleotide exon skipping in animal models of Duchenne muscular dystrophy -- PTD-DRBD siRNA delivery -- A non-covalent peptide-based strategy for siRNA delivery -- Application of pepfect peptides for the delivery of splice-correcting oligonucleotides -- Internalization of nucleoside phosphates into live cells by complex formation with different CPPs and JBS-nucleoducin -- Enhanced cellular delivery of cell-penetrating peptide-peptide nucleic acid conjugates by photochemical internalization -- Identification of homing peptides using the in vivo phage display technology -- Measuring the action of CPP-siRNA conjugates in the lung -- Intracellular delivery of nanoparticles with CPPs -- Multifunctional CPP polymer system for tumor-targeted pDNA and siRNA delivery -- Cell-penetrating penta-peptides and bax-inhibiting peptides: Protocol for their application -- Pair technology: Exon-specific rna-binding protein isolation in live cells -- Quantitation of cellular and topical uptake of luciferin-oligoarginine conjugates -- Industrial-scale manufacturing of a possible oligonucleotide cargo CPP-based drug -- Application of a fusiogenic peptide GALA for intracellular delivery -- Therapeutic applications of cell-penetrating peptides -- Nonclinical and clinical experiences with CPP-based self-assembling peptide systems in topical drug development.
  • v. 2, 1970.
    [By] Edmund B. Sandborn. Version française par Réal Gagnon, Pierre Jean [et] Bernard Messier.
    Status: Not Checked OutLane Catalog Record
  • 2012 Karger
    volume editors, Ludmila Filaretova, Koji Takeuchi.
    The 'gastric cytoprotection' concept of Andre Robert and the origins of a new series of international symposia / S. Szabo, Y. Tache, A. Tarnawski -- Importance of translational research in GI pharmacology : lessons learned from the successes in history / D. Chen, C.-M. Zhao -- Acetic acid ulcer model : state of the art in 2012 / S. Okabe, K. Amagase, K. Takeuchi -- Roles of EP4 receptors in protective and healing-promoting effects of prostaglandin E2 on NSAID-induced small intestinal damage / K. Takeuchi -- Role of food and enterobacteria in the formation and prevention of small intestinal damage induced by NSAIDS / H. Satoh, K. Takeuchi -- Synergic effect of NSAID and gastric acid on superoxide-anion production in stomach / H. Matsui, T. Kaneko -- Development of NSAIDS with lower gastric side effect / T. Mizushima -- Cell/tissue injury and cytoprotection/organoprotection in the gastrointestinal tract : mechanisms, prevention, and treatment / K.D. Rainsford -- Animal model for evaluating gastric bleeding and ulcerogenic response induced by aspirin plus clopidogrel / C. Izuhara ... [et al.] -- Effects of ibuprofen and some analogues on the muscle tone of isolated segments of the common digital artery of the fallow deer (Dama dama) / B.A. Callingham, Rainsford K.D. -- Psychological stress induces visceral analgesic or hyperalgesic response in rodents : a role of preconditions / A. Mulak, M. Larauche, Y. Tach -- Neurobiology of corticotropin-releasing factor in the enteric nervous system during stress / S. Liu, J.D. Wood -- Corticotropin-releasing factor may protect the gastric mucosa in stress through involvement of glucocorticoids / L.P. Filaretova ... [et al.] -- Pathogenic potential of psychogenic stress in gastric mucosal injury / V.I. Ovsiannikov, T.P. Berezina -- Advances in understanding inflammation in esophageal disease / R.H. Hunt, Y. Yuan -- Physiopathology of esophageal inflammation, ulcerogenesis, and repair by studying the profile of glycoconjugate / O. Zayachkivska -- Analysis of the effect of different neuropeptides in gastric mucosal defense initiated centrally / K. Gyires -- Sulforaphane enhances protection and repair of gastric mucosa against oxidative stress via Nrf2-dependent mechanisms / A. Yanaka -- Involvement of renin-angiotensin system and vasoactive angiotensin-(1-7) metabolite of angiotensin II in gastric mucosal injury and gastroprotection / T. Brzozowski ... [et al.] -- Effect of pentadecapeptide BPC 157 on gastrointestinal tract / P. Sikiric ... [et al.] -- Pathobiology of gastric carcinoids and adenocarcinomas in rodent models and patients : studies of gastrocystoplasty, gender-related factors, and autophagy / R.A. Vigen, D. Chen, C.M. Zhao -- Roles of the hydrogen sulfide/T-type calcium channel system in somatic and visceral pain processing / A. Kawabata, M. Matsunami -- Age-dependent role of vasopressin in susceptibility of gastric mucosa to indomethacin-induced injury / D. Zelena, O.Y. Morozova, L.P. Filaretova -- From mucosal energy metabolism to capsaicin : strategies for understanding mucosal protection / I.L. Szabcent, J. Czimmer, G. Mcentzsik.
  • 2014 Springer
    Laurent Nguyen, Simon Hippenmeyer, editors.
    Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches. Cellular and Molecular Control of Neuronal Migration also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians.
    Also available: Print – 2014
  • 2015 ClinicalKey
    Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai ; illustrations by David L. Baker, Alexandra Baker.
    Popular for its highly visual, straightforward approach, Cellular and Molecular Immunology delivers an accessible yet thorough understanding of this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present key updates in this new edition to cover the latest developments in antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more.
  • 2014 ClinicalKey
    edited by Monte S. Willis, MD, PhD, FCAP, FASCP, FAHA, University of North Carolina, UNC Health Care, McAllister Heart Institute, Department of Pathology & Laboratory Medicine, Chapel Hill, NC, USA, Jonathon W. Homeister, MD, PhD, FCAP, University of North Carolina, UNC Health Care, McAllister Heart Institute, Department of Pathology & Laboratory Medicine, Chapel Hill, NC, USA, James R. Stone, MD, PhD, Harvard Medical School, Massachusetts General Hospital, Department of Pathology, Boston, MA, USA.
    Focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine.
  • 2013 Springer Protocols
    edited by Volkmar Weissig, Tamer Elbayoumi, and Mark Olsen.
    Nanoparticle-GFP "chemical nose" sensor for cancer cell identification / Daniel F. Moyano and Vincent M. Rotello -- Method to map spatiotemporal pH changes in a multicellular living organism using a DNA nanosensor / Sunaina Surana and Yamuna Krishnan -- Simple method to visualize and assess the integrity of lysosomal membrane in mammalian cells using a fluorescent dye / Syed K. Sohaebuddin and Liping Tang -- Gold nanoparticle as a marker for precise localization of nano-objects within intracellular sub-domains / Valeriy Lukyanenko and Vadim Salnikov -- Immunoisolation of nanoparticles containing endocytic vesicles for drug quantitation / Ari Nowacek [and others] -- Methods for isolation and identification of nanoparticle-containing subcellular compartments / Ari Nowacek [and others] -- Permeabilization of cell membrane for delivery of nano-objects to cellular sub-domains / Valeriy Lukyanenko -- Method to encapsulate molecular cargo within DNA Icosahedra / Dhiraj Bhatia [and others] -- Delivery of plasmid DNA to mammalian cells using polymer-gold nanorod assemblies / James Ramos, Huang-Chiao Huang, and Kaushal Rege -- Lipophilic-formulated gold porphyrin nanoparticles for chemotherapy / Puiyan Lee and Kenneth K.Y. Wong -- Mitochondria-specific nano-emulsified therapy for myocardial protection against doxorubicin-induced cardiotoxicity / Amy Faulk, Volkmar Weissig, and Tamer Elbayoumi -- Formation of pit-spanning phospholipid bilayers on nanostructured silicon dioxide surfaces for studying biological membrane events / Indriati Pfeiffer and Michael Zach -- Characterization of nanoparticle-lipid membrane interactions using QCM-D / Rickard Frost and Sofia Svedhem -- Single-cell nanosurgery / Maxwell B. Zeigler and Daniel T. Chiu -- Single quantum dot imaging in living cells / Jerry C. Chang and Sandra J. Rosenthal -- Fabrication of fluorescent silica nanoparticles with aggregation-induced emission luminogens for cell imaging / Sijie Chen, Jacky W.Y. Lam, and Ben Zhong Tang -- Monitoring the degradation of reduction-sensitive gene carriers with fluorescence spectroscopy and flow cytometry / Constantin Hozsa, Miriam Breunig, and Achim Gopferich -- Quantification of intracellular mitochondrial displacements in response to nanomechanical forces displacements in response to nanomechanical forces / Yaron R. Silberberg and Andrew E. Pelling -- Imaging select mammalian organelles using fluorescent microscopy : application to drug delivery / Paul D.R. Dyer [and others] -- Real-time particle tracking for studying intracellular trafficking of pharmaceutical nanocarriers / Feiran Huang [and others] -- Interactions of nanoparticles with proteins : determination of equilibrium constants / Lennart Treuel and Marcelina Malissek -- Tracing the endocytic pathways and trafficking kinetics of cell signaling receptors using single QD nanoparticles / Katye M. Fichter and Tania Q. Vu -- Cellular internalization of quantum dots / Yue-Wern Huang [and others] -- Electrochemical scanning tunneling microscopy and spectroscopy for single-molecule investigation / Andrea Alessandrini and Paolo Facci -- Intracellular delivery of biologically active proteins with peptide-based carriers / Seong Loong Lo and Shu Wang -- Lipo-oligoarginine-based intracellular delivery / Jae Sam Lee and Ching-Hsuan Tung -- Fluorescent spherical monodisperse silica core-shell nanoparticles with a protein-binding biofunctional shell / Achim Weber, Marion Herz, and Gunter E.M. Tovar -- Direct quantification of PTD transduction using real-time monitoring / Mi-Sook Lee and Song Her -- Genotoxic assessment of carbon nanotubes / Olivera Neskovic [and others] -- Separation science : principles and applications for the analysis of bionanoparticles by asymmetrical flow field-flow fractionation (AF4) / Alexandre Moquin, Francoise M. Winnik, and Dusica Maysinger -- Polymersomes-mediated delivery of fluorescent probes for targeted and long-term imaging in live cell microscopy / Irene Canton and Giuseppe Battaglia -- Protocol for the preparation of stimuli-responsive gold nanoparticles capped with elastin-based pentapeptides / Vincent Lemieux, P. Hans H.M. Adams, and Jan C.M. van Hest.
  • 2013 Springer Protocols
    edited by Race L. Kao.
    Cellular cardiomyoplasty : its past, present, and future / Elizabeth K. Lamb, Grace W. Kao, and Race L. Kao -- Skeletal muscle stem cells / Grace W. Kao, Elizabeth K. Lamb, and Race L. Kao -- Bone marrow stem cells / Minh Ngoc Duong, Yu-Ting Ma, and Ray C.J. Chiu -- Adipose tissue-derived mesenchymal stem cells : isolation, expansion and characterization / Miriam Araña [and 4 others] -- Cardiac side population cells and Sca-1-positive cells / Toshio Nagai, Katsuhisa Matsuura, and Issei Komuro -- Two-step protocol for isolation and culture of cardiospheres / Lijuan Chen [and 5 others] -- Generation of human iPSCs from human peripheral blood mononuclear cells using non-integrative sendai virus in chemically defined conditions / Jared M. Churko, Paul W. Burridge, and Joseph C. Wu -- Identification of stem cells after transplantation / Yingjie Wang [and 5 others] -- Methods to study the proliferation and differentiation of cardiac side population (CSP) cells / Konstantina-Ioanna Sereti [and 3 others] -- Immune responses after mesenchymal stem cell implantation / Rony Atoui and Ray C.J. Chiu -- Route of delivery, cell retention, and efficiency of polymeric microcapsules in cellular cardiomyoplasty / Alice Le Huu [and 3 others] -- Angiogenic nanodelivery systems for myocardial therapy / Arghya Paul, Dominique Shum-Tim, and Satya Prakash -- Bio-hybrid tissue engineering for cellular cardiomyoplasty : future directions / Juan Carlos Chachques -- Decellularized whole heart for bioartificial heart / Hug Aubin [and 4 others] -- Clinical trials of cardiac repair with adult bone marrow-derived cells / Vinodh Jeevanantham [and 3 others] -- Clinical study using adipose-derived mesenchymal-like stem cells in acute myocardial infarction and heart failure / Ilia Alexander Panfilov [and 3 others].
  • 2007 ScienceDirect
    edited by J. Richard McIntosh.
    Physics of Rapid Cooling and Its Implications for Cryoimmobilization of Cells / J. Dubochet -- Cryopreparation Methods for Electron Microscopy of Selected Model Systems / K. McDonald -- Cryopreparation Methodology for Plant Cell Biology / M. W. Hess -- Correlative Light and Electron Microscopy of Early Caenorhabditis elegans Embryos in Mitosis / T. Muller-Reichert -- Understanding Microtubule Organizing Centers by Comparing Mutant and Wild-Type Structures with Electron Tomography / E. T. O'Toole -- Whole-Cell Investigation of Microtubule Cytoskeleton Architecture by Electron Tomography / J. L. Hoog -- Electron Microscopy of Archaea / C. E. Robertson -- Reconstructing Mammalian Membrane Architecture by Large Area Cellular Tomography / B. J. Marsh -- Visualization of Membrane-Cytoskeletal Interactions During Plant Cytokinesis / M. S. Otegui -- Electron Tomographic Methods for Studying the Chemical Synapse / C. P. Arthur -- Using Electron Microscopy to Understand Functional Mechanisms of Chromosome Alignment on the Mitotic Spindle / B. F. McEwen -- Electron Microscopic Analysis of the Leading Edge in Migrating Cells / T. Svitkina -- Imaging Actomyosin In Situ / K. A. Taylor -- Electron Tomography of Bacterial Chemotaxis Receptor Assemblies / P. Zhang -- How to "Read" a Vitreous Section / J. Dubochet -- Single-Particle Electron Cryomicroscopy of the Ion Channels in the Excitation-Contraction Coupling Junction / I. I. Serysheva -- Electron Microscopy of Microtubule-Based Cytoskeletal Machinery / A. Hoenger -- Reconstructing the Endocytotic Machinery / Y. Cheng -- 3D Immunolocalization with Plastic Sections / M. K. Morphew -- Electron Microscopy Analysis of Viral Morphogenesis / A. Pelchen-Matthews -- Electron Tomography of Immunolabeled Cryosections / M. S. Ladinsky -- Visualizing Macromolecules with Fluoronanogold: From Photon Microscopy to Electron Tomography / T. Cheutin -- Markers for Correlated Light and Electron Microscopy / G. E. Sosinsky -- Localizing Specific Elements Bound to Macromolecules by EFTEM / R. D. Leapman -- Localization of Protein Complexes by Pattern Recognition / C. Best -- The Application of Energy-Filtered Electron Microscopy to Tomography of Thick, Selectively Stained Biological Samples / J. C. Bouwer -- Optimization of Image Collection for Cellular Electron Microscopy / P. Mooney -- Future Directions for Camera Systems in Electron Microscopy / N. Xuong -- Structure Determination In Situ by Averaging of Tomograms / F. Forster -- Methods for Image Segmentation in Cellular Tomography / K. Sandberg -- Database Resources for Cellular Electron Microscopy / M. E. Martone.
    Also available: Print – 2007
  • 2012 ScienceDirect
    [edited by] Floris G. Wouterlood.
  • 2009 Springer
    Christian Ehnholm, editor.
  • 2013 ScienceDirect
    editors-in-chief, John L.R. Rubenstein, Pasko Rakic.
    The genetic, molecular, and cellular mechanisms of neural development are essential for understanding evolution and disorders of neural systems. Recent advances in genetic, molecular, and cell biological methods have generated a massive increase in new information, but there is a paucity of comprehensive and up-to-date syntheses, references, and historical perspectives on this important subject. The Comprehensive Developmental Neuroscience series is designed to fill this gap, offering the most thorough coverage of this field on the market today and addressing all aspects of how the nervous system and its components develop. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Each volume in the series consists of review style articles that average 15-20pp and feature numerous illustrations and full references. Volume 2 offers 56 high level articles devoted mainly to Formation of Axons and Dendrites, Migration, Synaptogenesis, Developmental Sequences in the Maturation of Intrinsic and Synapse Driven Patterns. Series offers 144 articles for 2904 full color pages addressing ways in which the nervous system and its components developFeatures leading experts in various subfields as Section Editors and article AuthorsAll articles peer reviewed by Section Editors to ensure accuracy, thoroughness, and scholarshipVolume 2 sections include coverage of mechanisms which regulate: the formation of axons and dendrites, cell migration, synapse formation and maintenance during development, and neural activity, from cell-intrinsic maturation to early correlated patterns of activity.
  • v. 1-4, 1999-2002. Springer
  • v. 5-, 2002- Springer
  • 2008
    edited by Miguel Maroto, Nicholas A.M. Monk.
    Calcium oscillations / Ruediger Thul ... [et al.] -- Oscillations by the p53-Mdm2 feedback loop / Galit Lahav -- cAMP oscillations during aggregation of dictyostelium / William F. Loomis -- Min oscillation in bacteria / Joe Lutkenhaus -- Development on time / Isabel Palmeirim ... [et al.] -- Oscillatory expression of HES family transcription factors : insights from mathematical modelling / Hiroshi Momiji and Nicholas A.M. Monk -- Reverse engineering models of cell cycle regulation / Attila Csikøsz-Nagy, Bøla Novøk, and John J. Tyson -- Mitochondrial oscillations in physiology and pathophysiology / Miguel A. Aon, Sonia Cortassa, and Brian O'Rourke -- Respiratory oscillations in yeasts / David Lloyd -- Stochastic phase oscillator models for circadian clocks / Jacques Rougemont and Felix Naef.
  • 2014 Springer
    W. Glenn McCluggage, John Tidy, John H.F. Smith.
    This book provides a comprehensive account of the cellular pathology of glandular lesions and uncommon neoplasms of the cervix and places these in a contemporary clinical context. The book features comprehensive, detailed descriptions and a consistent approach to each tumor or tumor-like condition with clear color illustrations. Cytological/histological correlation is emphasised and diagnostic pitfalls are highlighted. Cellular Pathology of Glandular Lesions and Uncommon Neoplasms of the Cervix is aimed at both trainee and consultant pathologists.
  • 2010 Springer
    Jens F. Rehfeld, Jens R. Bundgaard (eds.).
    Also available: Print – 2010
  • 2012 Springer
    [edited by] Livio Luzi.
    1. Human Evolution and Physical Exercise: The Concept of Being "Born to Run" / Livio Luzi -- 2. Cell Morphology and Function: The Specificities of Muscle Cells / Anna Maestroni -- 3. The Cell Membrane of the Contractile Unit / Gianpaolo Zerbini -- 4. Gene Polymorphisms and Athletic Performance / Ileana Terruzzi -- 5. Nutrients and Whole-Body Energy Metabolism: The Impact of Physical Exercise / Stefano Benedini -- 6. Mitochondrial and Non-mitochondrial Studies of ATP Synthesis / Roberto Codella -- 7. Excessive Nutrients and Regional Energy Metabolism / Gianluca Perseghin -- 8. Muscle Biopsy To Investigate Mitochondrial Turnover / Rocco Barazzoni -- 9. Introduction to the Tracer-Based Study of Metabolism In Vivo / Andrea Caumo and Livio Luzi -- 10. Physical Activity and Inflammation / Raffaele Di Fenza and Paolo Fiorina -- 11. The HPA Axis and the Regulation of Energy Balance / Francesca Frigerio -- 12. Physical Exercise in Obesity and Anorexia Nervosa / Alberto Battezzati and Simona Bertoli -- 13. Physical Exercise and Transplantation / Valentina Delmonte, Vincenzo Lauriola, Rodolfo Alejandro and Camillo Ricordi -- 14. The Baboon as a Primate Model To Study the Physiology and Metabolic Effects of Exercise / Francesca Casiraghi, Alberto Omar Chavez, Nicholas Musi and Franco Folli.
  • 2012 ClinicalKey
    edited by Mordecai P. Blaustein, Joseph P.Y. Kao, Donald R. Matteson.
    Introduction : homeostasis and cellular physiology -- Diffusion and permeability -- Osmotic pressure and water movement -- Electrical consequences of ionic gradients -- Ion channels -- Passive electrical properties of membranes -- Generation and propagation of the action potential -- Ion channel diversity -- Electrochemical potential energy and transport processes -- Passive solute transport -- Active transport -- Synaptic physiology I -- Synaptic physiology II -- Molecular motors and the mechanism of muscle contraction -- Excitation-contraction coupling in muscle -- Mechanics of muscle contraction.
  • 2013 CRCnetBASE
    Marco Scianna and Luigi Preziosi.
    "All biological phenomena emerge from an intricate interconnection of multiple processes occurring at different levels of organization: namely, at the molecular, the cellular and the tissue level, see Figure 1. These natural levels can approximately be connected to a microscopic, mesoscopic, and macroscopic scale, respectively. The microscopic scale refers to those processes that occur at the subcellular level, such as DNA synthesis and duplication, gene dynamics, activation of receptors, transduction of chemical signals, diffusion of ions and transport of proteins. The mesoscopic scale, on the other hand, can refer to cell-level phenomena, such as adhesive interactions between cells or between cells and ECM components, cell duplication and death and cell motion. The macroscopic scale finally corresponds to those processes that are typical of multicellular behavior, such as population dynamics, tissue mechanics and organ growth and development. It is evident that research in biology and medicine needs to work in a multiscale fashion. This brings many challenging questions and a complexity that can not be addressed in the classical way, but can take advantage of the increasing collaboration between natural and exact sciences (for more detailed comments the reader is referred to [90, 262]). On the other hand, the recent literature provides evidence of the increasing attention of the mathematical, statistical, computational and physical communities toward biological and biomedical modeling, consequence of the successful results obtained by a multidisciplinary approach to the Life Sciences problems"-- Provided by publisher.
  • ScienceDirect
    edited by Anthony R. Means, P. Michael Conn.
    Also available: Print – 1987
  • ScienceDirect
    edited by P. Michael Conn, Anthony R. Means.
    Also available: Print – 1987
  • 2009 Springer
    Shireesh P. Apte, Rangaprasad Sarangarajan, editors ; foreword by Gregg L. Semenza.
  • 2010 Springer
    Peter D. Adams, John M. Sedivy, editors.
  • 2005 Karger
    volume editors, Mohammed S. Razzaque, Takashi Taguchi.
    Involvement of stress proteins in renal diseases / Razzaque, M.S., Taguchi, T. -- Stress proteins in glomerular epithelial cell injury / Bijian, K., Cybulsky, A.V. -- Response of renal medullary cells to osmotic stress / Neuhofer, W., Beck, F.-X. -- Heat shock proteins in renal cell carcinomas / Atkins, D., Lichtenfels, R., Seliger, B. -- Heat shock protein 47 and renal fibrogenesis / Razzaque, M.S., Taguchi, T. -- Cytoprotective effects of heme oxygenase in acute renal failure / Akagi, R., Takahashi, T., Sassa, S. -- Heat shock (stress response) proteins and renal ischemia/reperfusion injury / Kelly, K.J. -- Cisplatin-associated nephrotoxicity and pathological events / Taguchi, T. ... [et al.] -- Oxidant stress in renal pathophysiology / Abid, A.R., Razzaque, M.S., Taguchi, T. -- Heat shock proteins and allograft rejection / Pockley, A.G.; Muthana, M.
    Also available: Print – 2005
  • 2015 Springer
    edited by Li-Ru Zhao, John H. Zhang.
    The first book to focus on cellular therapy for stroke and other CNS injuries. Addresses recent research on all relevant cell types including neural stem cells, bone marrow stem cells, endothelial progenitor cells, and many others that have had protective or regenerative effects in animal models. Cellular therapy for stroke and neural trauma has gained worldwide attention during the last decade and has shown some promising results. The book also provides information on cell isolation and culture skills, transplantation methods, and neurological functional evaluations.
  • 2012 Springer
    Brian Henderson, A. Graham Pockley, editors.
    Section 1 Historical Introduction to Secreted Cell Stress Proteins as Signalling Proteins -- Discovery of the Cellular Secretion of Cell Stress Proteins -- Discovery of the Agonist Activities of Molecular Chaperones and Protein-Folding Catalysts -- Identification of Cell Stress Proteins in Biological Fluids -- Section 2 Intracellular Trafficking of Molecular Chaperones and its Consequences -- Hsp27 Phosphorylation Patterns and Cellular Consequences -- Evidence on Cholesterol-Controlled Lipid Raft Interaction of the Small Heat Shock Protein HSPB11 -- Hsp70 Chaperone Systems in Vesicular Trafficking -- Pathways of Hsp70 Release: Lessons from Cytokine Secretion -- Nucleolin: A Novel Intracellular Transporter of HSPA1A -- The Hsp90-Based Protein Trafficking System and Linkage to Protein Quality Control -- Section 3 Molecular Chaperones as Cell Surface Receptors and Receptor Ligands -- Cell Surface Molecular Chaperones and the LPS Receptor -- Hsp60: An Unexpected Cell Surface Receptor in Prokaryotes and Eukaryotes -- Pathophysiological Barriers Impeding the Delivery of Heat Shock Protein (HSP)-based Macromolecules and Nanotherapeutics to Solid Tumors -- The Chaperokine Activity of HSPA1A -- Molecular Chaperones and Scavenger Receptors: Binding and Trafficking of Molecular Chaperones by Class F and Class H Scavenger Receptors -- Grp78 (BiP): A Multifunctional Cell Surface Receptor -- Section 4 Extracellular Secretion of Molecular Chaperones in Prokaryotes and Eukaryotes -- Mycobacterium Tuberculosis Hsp60 as a Key Virulence Factor in Tuberculosis -- Hsp90 vs Conventional Growth Factors in Acute and Diabetic Wound Healing -- Circulating Molecular Chaperones in Health and Disease -- Index.
  • 2012 ScienceDirect
    edited by Harry J. Gilbert.
    Cellulase refers to a class of enzymes produced chiefly by fungi, bacteria, and protozoans that catalyze cellulolysis. This volume in the Methods in Enzymology series comprehensively covers this topic.
  • 2014 ScienceDirect
    Lorenzo Galluzzi and Guido Kroemer editors.
  • 2015
    M. Becker [and others].
    Status: Not Checked OutLane Catalog Record
  • 2009
    Kirstin Jane Milks.
    Status: Not Checked OutLane Catalog Record
  • 2010
    Korean-American Medical Association.
    Status: Not Checked OutLane Catalog Record
    Korean-American pioneers in medicine -- Presence of Korean-American physicians and the birth of KAMA -- Activities of KAMA: 1974-2010 -- Photographs -- Activities of alumni associations of Korean medical schools and U.S. graduates -- Biosketches of physicians recognized in professional societies and/or community achievement -- Roster of KAMA members -- By-laws of the Korean-American Medical Association.
  • 2011 Springer
    Seymour B. Sarason ; foreword by Saul B. Carson.
    As people live longer and health care costs continue to rise and fewer doctors choose to specialize in geriatrics, how prepared is the United States to care for its sick and elderly? According to veteran psychologist Seymour Sarason's eloquent and compelling new book, the answer is: inadequately at best. And rarely discussed among the grim statistics is the psychosocial price paid by nursing home patients, from loneliness and isolation to depression and dependency. In "Centers for Ending", Dr. Sarason uses his firsthand experience as both practitioner and patient in senior facilities.
  • 2009 Springer
    Kimitaka Kaga.
  • 2014 ScienceDirect
    volume editors, Gert Holstege, Caroline M. Beers, Hari H. Subramanian.
    Respiration is one of the most basic motor activities crucial for survival of the individual. It is under total control of the central nervous system, which adjusts respiratory depth and frequency depending on the circumstances the individual finds itself. For this reason this volume not only reviews the basic control systems of respiration, located in the caudal brainstem, but also the higher brain regions, that change depth and frequency of respiration. Scientific knowledge of these systems is crucial for understanding the problems in the many patients suffering from respiratory failure.
  • 2008 Springer
    Thomas E. Lane ... [et al.], editors.
  • 2009 Springer
    Derek S. Wheeler, Hector R. Wong, and Thomas P. Shanley (eds.).
    "The field of critical care medicine is in the midst of a dramatic change. Technological and scientific advances during the last decade have resulted in a fundamental change in the way we view disease processes, such as sepsis, shock, acute lung injury, and traumatic brain injury. Pediatric intensivists have been both witness to and active participants in bringing about these changes and it is imperative that all physicians caring for critically ill children in this new era have a thorough understanding of the applicability of these modern developments to the care of patients at the bedside and to keep up with the rapidly evolving field of critical care medicine. Neurologic emergencies are a common reason for admission to the pediatric intensive care unit (PICU). A thorough understanding of the diseases and disorders affecting the pediatric central nervous system is vital for any physician or health care provider working in the PICU. The Central Nervous System in Pediatric Critical Illness and Injury has been written by an international panel of experts to provide readers with an in-depth discussion on the resuscitation, stabilization, and ongoing care of the critically ill or injured child with central nervous system dysfunction. This book is therefore absolutely crucial for anyone working in the PICU, from physicians, residents and fellows in critical care, neurology, and pediatrics to specialist nurses and support personnel on the PICU and all medical professionals who are involved in the management of these patients."--Publisher's website.
  • 2014 Springer
    César R. Lacruz, Javier Sáenz de Santamaría, Ricardo H. Bardales.
    The Essentials in Cytopathology book series fulfills the need for an easy-to-use and authoritative synopsis of site specific topics in cytopathology. These guide books fit into the lab coat pocket and are ideal for portability and quick reference. Each volume is heavily illustrated with a full color art program, while the text follows a user-friendly outline format. Central Nervous System Intraoperative Cytopathology covers the full spectrum of benign and malignant conditions of the CNS with emphasis on common disorders. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in the field of intraoperative neuro-cytopathology. Central Nervous System Intraoperative Cytopathology is a valuable quick reference for pathologists, cytopathologists, and fellows and trainees dealing with this exigent field.
  • 2012 Springer
    Diane Palmieri, editor.
    Introduction to brain metastasis / Diane Palmieri -- Molecular biology of brain metastasis / Stephan Woditschka ... [et al.] -- Brain microenvironment / Mami Noda -- Vascular permeability within brain metastases / Chris E. Adkins ... [et al.] -- Imaging experimental brain metastases / Amanda M. Hamilton and Paula J. Foster -- Possibilities of targeted therapies for brain metastasis / Frank Winkler -- Surgery for brain metastasis / Douglas L. Stofko, Robert J. Weil, and Steven A. Toms -- Is there a role for systemic chemotherapy in the treatment of brain metastases / Marc C. Chamberlain -- Radiation therapy of CNS metastases / DeeDee Smart -- Leptomeningeal metastasis / Priscilla K. Brastianos, Charilaos H. Brastianos, and April F. Eichler -- Quality of life with CNS metastasis / Lauren A. Chandler and Kathleen L. Fuchs.
  • 2011 Cambridge
    Sergio Canavero, Vincenzo Bonicalzi.
    Part I. Introduction: 1. Introduction; Part II. Clinical Features and Diagnosis: 2. Epidemiology; 3. Clinical features; 4. Somatosensory findings; 5. Central pruritus; 6. Natural history; 7. Central pain allied conditions and special considerations; 8. Diagnosing central pain; Part III. Treatment: 9. Drug therapy; 10. Neuromodulation; 11. Cortical stimulation; 12. Deep brain stimulation; 13. Spinal cord stimulation; 14. Transcutaneous electrical nerve stimulation; 15. Other stimulation techniques; 16. Intraspinal drug infusion; 17. Alternative and complementary approaches; 18. Conclusions on therapy; Part IV. Pathophysiology: 19. Introduction to pathophysiology; 20. Sudden disappearances of central pain; 21. Results of neuroablation; 22. Neurophysiological studies; 23. Imaging studies; 24. Drug dissection; 25. Is this a spinal generator of central pain?; 26. Attractor-driven dynamic reverberation.
  • 2007
    Eszter Katalin Vladar.
    Status: Not Checked OutLane Catalog Record
  • 2009 Springer
    Đurđica Ugarković, editor.
  • 2012 Springer
    Heide Schatten, editor.
    Part I. Centrosomes in Reproduction -- 1. Centriole Duplication and Inheritance in Drosophila melanogaster / Tomer Avidor-Reiss, Jayachandran Gopalakrishnan, Stephanie Blachon and Andrey Polyanovsky -- 2. Sperm Centrioles and Their Dual Role in Flagellogenesis and Cell Cycle of the Zygote: Structure, Function, and Pathology / Hector E. Chemes -- 3. Centrosomal Functions and Dysfunctions in Cat Spermatozoa / Pierre Comizzoli and David E. Wildt -- 4. Nuclear-Centrosome Relationships During Fertilization, Cell Division, Embryo Development, and in Somatic Cell Nuclear Transfer Embryos / Heide Schatten and Qing-Yuan Sun -- 5. Human Centrosomal Dynamics During Gametogenesis, Fertilization, and Embryogenesis and Its Impact on Fertility: Ultrastructural Analysis / A. Henry Sathananthan -- 6. Asymmetric Centrosome Behavior in Stem Cell Divisions / Therese M. Roth, Yukiko M. Yamashita and Jun Cheng -- Part II. Cell and Molecular Biology of Centrosomes -- 7. Functional Associations Between the Golgi Apparatus and the Centrosome in Mammalian Cells / Breanne Karanikolas and Christine Sütterlin -- 8. Many Pathways to Destruction: The Role of the Centrosome in, and Its Control by Regulated Proteolysis / Harold A. Fisk -- 9. Regulation of the Centrosome Cycle by Protein Degradation / Suzanna L. Prosser and Andrew M. Fry -- 10. Molecular Links Between Centrosome Duplication and Other Cell Cycle-Associated Events / Kenji Fukasawa -- 11. Regulation of Centrosomes by Cyclin-Dependent Kinases / Rose Boutros -- Part III. Centrosome Abnormalities in Cancer -- 12. Disruption of Centrosome Duplication Control and Induction of Mitotic Instability by the High-Risk Human Papillomavirus Oncoproteins E6 and E7 / Nina Korzeniewski and Stefan Duensing -- 13. Centrosomes, DNA Damage and Aneuploidy / Chiara Saladino, Emer Bourke and Ciaran G. Morrison -- 14. Centrosome Regulation and Breast Cancer / Zeina Kais and Jeffrey D. Parvin -- 15. The Role of Centrosomes in Multiple Myeloma / Benedict Yan and Wee-Joo Chng -- 16. Centrosomal Amplification and Related Abnormalities Induced by Nucleoside Analogs / Ofelia A. Olivero -- 17. Mechanisms and Consequences of Centrosome Clustering in Cancer Cells / Alwin Krämer, Simon Anderhub and Bettina Maier -- Part IV. Centrosomes in Other Systems -- 18. Re-evaluation of the Neuronal Centrosome as a Generator of Microtubules for Axons and Dendrites / Peter W. Baas and Aditi Falnikar -- 19. Centrosomes and Cell Division in Apicomplexa / Leandro Lemgruber, Marek Cyrklaff and Freddy Frischknecht -- 20. The Centrosome Life Story in Xenopuslaevis / Jacek Z. Kubiak and Claude Prigent -- 21. Role of the MTOC in T Cell Effector Functions / Martin Poenie, Laura Christian, Sarah Tan and Yuri Sykulev -- 22. Thoughts on Progress in the Centrosome Field / Jeffrey L. Salisbury.
  • 2015 ScienceDirect
    [edited by] Renata Basto and Karen Oegema.
    This new volume of Methods in Cell Biology looks at methods for analyzing centrosomes and centrioles. Chapters cover such topics as methods to analyze centrosomes, centriole biogenesis and function in multi-ciliated cells, laser manipulation of centrosomes or CLEM, analysis of centrosomes in human cancers and tissues, proximity interaction techniques to study centrosomes, and genome engineering for creating conditional alleles in human cells.
  • 2012
    Joanna Y. Lee.
    Chromosomal translocations fusing genes that encode centrosome proteins and tyrosine kinases are frequently observed in myeloproliferative neoplasms (MPNs). Although the function of centrosome proteins in these fusions is not well understood, roles that may contribute to proliferative signaling including kinase centrosome localization and constitutive kinase dimerization have long been postulated. To test the relative contributions of localization and dimerization on kinase signaling efficiency, we targeted inducibly dimerizable FGFR1 to several subcellular locations and generated a centrosome localization mutant of the FOP-FGFR1 MPN fusion. Expression in mammalian tissue culture cells followed by substrate phosphorylation assays reveals a statistically significant decrease in kinase signaling effectiveness upon loss of FOP-FGFR1 centrosome localization. Interestingly, wild-type FOP-FGFR1 expression also caused a centrosome localization-dependent ciliogenesis defect. Further studies revealed that the fusion partner, FOP, localizes to centriolar satellites in addition to its previously described centrosomal localization. Centriolar satellites are granules clustered around the centrosome suspected to function in microtubule anchoring, protein trafficking, and ciliogenesis, though their precise function and composition remain unknown. Satellite localization is retained in the FOP-FGFR1 fusion and an increase in phosphotyrosine activity occurs at satellites in FOP-FGFR1 expressing cells. Given the importance of centriolar satellites in ciliogenesis, and the link between ciliogenesis and proliferative signaling, it is possible that increased phosphotyrosine activity at satellites is functionally significant in the progression of MPN. Finally, we assayed for ciliary signaling proteins in chronic myelogenous leukemia (CML) cells. Although FOP-FGFR1 causes a ciliogenesis defect, MPN affects blood cells, which have not been reported to contain cilia. We show here that, although CML cells do not appear to form a primary cilium, they contain masses of stabilized tubulin that co-localize with ciliary proteins. This may be evidence for a form of ciliary signaling in unciliated mammalian cells.
  • 2001 ScienceDirect
    Robert E. Palazzo, Trisha N. Davis.
    Also available: Print – 2001
  • 2011
    Timothy Richard Stowe.
    Centrosomes and cilia are evolutionarily conserved organelles with important functions in cell signaling, organismal development and disease. Defects in centrosome and cilium function are associated with a set of phenotypically-related syndromes called ciliopathies. To discover new centrosome/cilium components, candidate genes were identified by virtue of their transcriptional upregulation in multiciliated tracheal epithelial cells and selected for further study based on their subcellular localization. Using this approach, Cep72 was identified as a component of centriolar satellites - poorly understood centrosome-associated structures defined by the protein PCM1. A subset of ciliopathy-associated proteins that includes BBS4, Cep290 and OFD1 associate with centriolar satellites, yet how this association affects their function is unknown. Cep72 was determined to be a PCM1-interacting protein and its association with centriolar satellites was characterized in detail. Cep72 was found to interact with Cep290 and overexpression/depletion experiments demonstrated that Cep72 facilitates recruitment of Cep290, but not BBS4, to centriolar satellites. Loss of satellites by depletion of PCM1 resulted in cytoplasmic disperal of BBS4 and redistribution of Cep72 and Cep290 from centriolar satellites to the centrosome. In contrast to the reported function of centriolar satellites in facilitating the localization of proteins to the centrosome, the effects of PCM1 depletion on Cep72 and Cep290 localization suggest that association with centriolar satellites can also restrict centrosomal localization for some proteins. During ciliogenesis, BBS4 transitions from centriolar satellites to the primary cilium, however regulation of this transition is not understood. Depletion of Cep72 or Cep290 prevented transition of BBS4 localization, causing BBS4 to remain localized to centriolar satellites in ciliated cells. Depletion of PCM1 or Cep72 in developing zebrafish embryos resulted in phenotypes consistent with centrosome/cilium defects, suggesting centriolar satellites influence cilium function during development. Given these results, we propose that centriolar satellites function in modulating the ciliary localization of BBS4 and possibly other ciliogenesis factors, via a mechanism that involves Cep290 as an effector of that regulation. The distribution of centriolar satellites around the centrosome during interphase requires microtubules and dynein. During the cellular stress response to misfolded proteins, protein aggregates are transported in a microtubule and dynein-dependent manner to structures surrounding the centrosome referred to as aggresomes. We observed PCM1-dependent recruitment of centriolar satellite proteins to aggresomes, which prompted further investigation of the potential involvement of PCM1 in aggresome formation. Depletion of PCM1 had modest effects on aggresome formation and cell viability in response to misfolded proteins. However the influence of PCM1 on centrosome function and microtubule organization could not be ruled out as possible explanation for these effects.
  • 2014 Springer
    Jonathan Davidson.
    Samuel Hahnemann: Rebarbative Genius -- Women, Reform, and Medical Leadership -- The Homeopathic Scalpel: Contributions to Surgery from the World of Homeopathy -- Homeopaths and the Dawning of Anesthesiology -- Homeopathy and the Mind: From Alienists to Neuroscientists -- Public Health -- The Early Days of Radiation: Homeopathic Shadows -- Heartbeat, Heart Failure, and Homeopathy -- Allergy and Allergic Disorders: Homeopathic Leaders -- Academic Homeopaths Reinvented -- Oncology -- Other Stars in the Sky -- Congress, Parliament, Presidents, and Monarchs -- Bioethics and the Contributions of Otto Guttentag -- Less Is More: Finding the Right Dose -- A Homeopathic Rogues' Gallery -- Concluding Thoughts.
  • 2007 Wiley
    Kang Li.
    Chapter 1 Ceramic Membranes and Membrane Processes, p. 1-20 -- Chapter 2. Preparation of Ceramic Membranes, p. 21-57 -- Chapter 3. Characterization of Ceramic Membranes, p. 59-95 -- Chapter 4. Transport and Separation of Gases in Porous Ceramic Membranes, p. 97-134 -- Chapter 5. Ceramic Hollow Fibre Membrane Contactors for Treatment of Gases/Vapours, p. 135-168 -- Chapter 6 Mixed Conducting Ceramic Membranes for Oxygen Separation, p. 169-215 -- Chapter 7. Mixed Conducting Ceramic Membranes for Hydrogen Permeation, p. 217-243 -- Chapter 8. Ceramic Membrane Reactors, p. 245-298.
  • 2014 Springer Protocols
    edited by Robert J. Henry, Agnelo Furtado.
    DNA Extraction from Vegetative Tissue for Next Generation Sequencing? -- DNA Extraction from Rice Endosperm (Including a Protocol for Extraction of DNA from Ancient Seed Samples) -- RNA Extraction from Cereal Vegetative Tissue -- RNA Extraction from Developing or Mature Wheat Seeds -- cDNA Library Preparation -- Preparation of High Molecular Weight gDNA and Bacterial Artificial Chromosome (BAC) Libraries in Plants -- The Polymerase Chain Reaction (PCR) -- General Methods -- Mutation and Mutation Screening -- The Quantitative Real-Time Polymerase Chain Reaction for the Analysis of Plant Gene Expression -- Cloning of DNA Fragments: Ligation Reactions in Agarose Gel -- Rapid Cloning of Genes and Promoters for Functional Analyses -- Genome Walking -- Functional Analysis by Protein Biochemistry -- Genomic Southern Blot analysis -- Northern Hybridization: A Proficient Method for Detection of Small RNAs and MicroRNAs -- Protein Blotting-Protocol for Beginners -- Genetic Transformation of Wheat via Particle Bombardment -- Sorghum Genetic Transformation by Particle Bombardment -- Genetic Transformation of Wheat via Agrobacterium-mediated DNA Delivery -- A Protocol for High-throughput Agrobacterium-mediated Barley Transformation -- Agrobacterium-mediated Transformation- Rice Transformation -- Agrobacterium-mediated Transformation of Maize (Zea mays) Immature Embryos -- A Technical Platform for PCR-based SNP Screening in Cereals and Other Crops -- A Method for Discovery of Genome-wide SNP Between Any Two Genotypes from Whole Genome Re-sequencing Data.
  • 2014 ScienceDirect
    edited by Narender Ramnani.
    Progress in Brain Research is the most acclaimed and accomplished series in neuroscience, firmly established as an extensive documentation of the advances in contemporary brain research. The volumes, some of which are derived from important international symposia, contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biologi
  • 2014 Springer Protocols
    edited by Richard Milner.
    Cerebral Angiogenesis During Development: Who is Conducting the Orchestra? -- Cerebral Angiogenesis: A Realistic Therapy for Ischemic Disease? -- Vascular Normalization in Cerebral Angiogenesis: Friend or Foe? -- Pericytes and Adaptive Angioplasticity: The Role of Tumor Necrosis Factor Weak Inducer of Apoptosis (TWEAK) -- Analysis of Angiogenesis in the Developing Mouse Central Nervous System -- Hypoxia-Induced Angiogenesis and Capillary Density Determination -- The Middle Cerebral Artery Occlusion Model of Transient Focal Cerebral Ischemia -- A Mouse Model of Chronic Cerebral Hypoperfusion Characterizing Features of Vascular Cognitive Impairment -- A Mouse Model of Permanent Focal Ischemia: Distal Middle Cerebral Artery Occlusion -- A Method of Inducing Global Cerebral Ischemia -- Induction of Cerebral Arteriogenesis in Mice -- Vessel Painting Technique for Visualizing the Cerebral Vascular Architecture of the Mouse -- Examining Cerebral Angiogenesis in Response to Physical Exercise -- Histological Assessment of Angiogenesis in the Hypoxic Central Nervous System -- Examining Vascular Remodeling in the Hypoxic Central Nervous System -- Analysis of Cerebral Angiogenesis in Human Glioblastomas -- Quantitative Cerebral Blood Flow Measurements Using MRI -- Fluorescent Angiogenesis Models Using Gelfoam? Implanted in Transgenic Mice Expressing Fluorescent Proteins -- Laser Speckle Contrast Imaging to Measure Changes in Cerebral Blood Flow -- Laser Doppler Flowmetry to Measure Changes in Cerebral Blood Flow -- Defining the Role Of HIF and Its Downstream Mediators in Hypoxic-Induced Cerebral Angiogenesis -- Inducible Gene Deletion in Glial Cells to Study Angiogenesis in the Central Nervous System -- Bone Marrow Chimera Experiments to Determine the Contribution of Hematopoietic Stem Cells to Cerebral Angiogenesis -- Novel Methods for Accurate Identification, Isolation, and Genomic Analysis of Symptomatic Micro-Environments in Atherosclerotic Arteries -- Induction of Brain Arteriovenous Malformation in the Adult Mouse -- Stimulation of Cerebral Angiogenesis by Gene Delivery -- Investigating the Role of Perlecan Domain V in Post-Ischemic Cerebral Angiogenesis -- Isolation and Culture of Primary Mouse Brain Endothelial Cells -- Purification of Endothelial Cells from the Rat Brain -- Generation of Primary Cultures of Bovine Brain Endothelial Cells and Setup of Co-Cultures with Rat Astrocytes -- Isolation and Culture of Primary Pericytes from Mouse Brain -- Assays to Examine Endothelial Cell Migration, Tube Formation, and Gene Expression Profiles -- A Neurovascular Blood-Brain Barrier In Vitro Model -- In Vitro Models of the Blood-Brain Barrier.
  • 2014 Springer
    Gianni Boris Bradac.
    This revised and enlarged edition of Cerebral Angiography, which includes new angiographic studies and illustrative drawings, offers detailed guidance on diagnostic use of the procedure. The first part of the book describes the normal anatomy of the cerebral arteries and veins, with attention to morphological aspect, embryological development, function, and vascular territories. The intraorbital and extracranial vascularization is also considered. The reader will gain a sound knowledge of normal vascular anatomy and its variations that will serve as a basis for the correct interpretation of pathological processes and their clinical significance, as covered in the second part of the book. Among the pathologies considered are vascular abnormalities, including angiomas, fistulas and aneurysms; atherosclerotic and non-atherosclerotic stenosis and occlusion of the cerebral vessels; venous thrombosis; intraorbital and extracranial vascular malformations. Pathogenesis, morphological and dynamic aspects, responsible for clinical symptoms and influencing the therapy are described. While the emphasis throughout is on the diagnostic value of cerebral angiography, many examples of endovascular treatment in different pathological situations are also presented, with discussion of indications, risks and results.
  • 2011 Springer
    Gianni Boris Bradac.
  • 2013 Springer
    Christian W. Kreipke, Jose A. Rafols, editors.
    Historical Perspectives in Understanding Traumatic Brain Injury and in Situating Disruption in CBF in the Pathotrajectory of Head Trauma / Christopher Betrus and Christian W. Kreipke -- Situating Cerebral Blood Flow in the Pathotrajectory of Head Trauma / Justin Graves, Christopher Betrus and Jose A. Rafols -- Modeling of Traumatic Brain Injury and its Implications in Studying the Pathology of Repeated Mild Impacts to the Head / Michael J. Kane, Mariana Angoa Pérez, Denise I. Briggs, David C. Viano and Christian W. Kreipke, et al. -- The Presence of Venous Damage and Microbleeds in Traumatic Brain Injury and the Potential Future Role of Angiographic and Perfusion Magnetic Resonance Imaging / E. M. Haacke, Waqar Raza, Bo Wu and Zhifeng Kou -- Situating the Endothelin System in the Pathotrajectory of TBI-Induced Changes in Hemodynamics / Anthony Kropinski, Paula Dore-Duffy and Christian W. Kreipke -- Age and Sex Differences in Cerebral Blood Flow and Autoregulation after Pediatric Traumatic Brain Injury / William M. Armstead and Monica S. Vavilala -- New Frontiers in Clinical Trials Aimed at Improving Outcome Following Traumatic Brain Injury / Christian W. Kreipke, Anthony Kropinski, Justin Graves, David Tiesma and Michael Kaufman, et al.
  • 2008 Springer
    edited by Liang-Fu Zhou ... [et al.].
    Also available: Print – 2008
  • 2005 Springer
    edited by Enno Freye.
    Cerebral monitoring in the operating room and the intensive care unit: an introductory for the clinician and a guide for the novice wanting to open a window to the brain. Part I: the electroencephalogram / Enno Freye and Joseph V. Levy -- Part II: sensory-evoked potentials (SSEP, AEP, VEP) / Enno Freye -- Part III: spinal cord evoked potentials / Enno Freye.
  • 2005 Springer
    Freeman Miller.
  • 2014 ScienceDirect
    edited by Roberta B. Shepherd.
    This is a thought-provoking book which introduces a new way of thinking on the development and use of interventions. Relevant to current practice, it advocates early, targeted activity that is focused on increasing muscle activation, training basic actions and minimizing (or preventing) mal-adaptive changes to muscle morphology and function. The authors present recent scientific findings in brain science, movement sciences (developmental biomechanics, motor control mechanisms, motor learning, exercise science) and muscle biology. This knowledge provides the rationale for active intervention, underpinning the need for an early referral to appropriate services. The book features methods for promoting relatively intensive physical activity in young infants without placing a burden on parents which include assistive technologies such as robotics, electronic bilateral limb trainers and baby treadmills. This book begins by specifying the guidelines for training and exercise, outlining the rationale for such intervention. It goes on to cover the fundamentals of neuromotor plasticity and the development and negative effects of limited motor activity on brain organization and corticospinal tract development. Neuromuscular adaptations to impairments and inactivity are discussed along with the General Movement assessment that can provide early diagnosis and prognosis, facilitating very early referral from paediatric specialists to training programs. The book ends with a section featuring various methods of training with the emphasis on preventing/minimizing muscle contracture, stimulating biomechanically critical muscle activity and joint movement.
  • 2011 Thieme eNeurosurgery
    [edited by] Eric S. Nussbaum, J. Mocco.
    Eric S. Nussbaum and J. Mocco renowned surgical experts combine their expertise to provide the most current and comprehensive coverage of open brain bypass and endovascular options currently available. A detailed introduction familiarizes readers with the various indications for these technically demanding procedures. Concise chapters then supply thorough coverage of surgical strategies, complications, and outcomes using case examples from the authors' own collections to help prepare readers for surgery. Enhancing the text throughout, operative photographs and angiographic images clearly demonstrate the pre-, peri-, and postoperative management of ischemic stroke, giant aneurysms, and the spectrum of complex cerebrovascular diseases. Neurosurgeons, residents, and fellows will regularly refer to this definitive guide in both the operating room and the catheterization lab. It is also an indispensable resource for interventional radiologists, neurologists, vascular neurosurgeons, or for anyone who needs to learn more about these cutting-edge cerebral revascularization techniques.
  • 2011 ClinicalKey
    [edited by] Saleem I. Abdulrauf.
    Section 1. Cerebral hemodynamics and cerebrovascular imaging -- section 2. EC-IC bypass surgical techniques -- section 3. Cerebral ischemia -- section 4. Giant cerebral aneurysms -- section 5. Skull base tumors.
  • 2014 Cambridge
    edited by Leonardo Pantoni, MD, PhD, Staff Neurologist, Stroke Unit and Neurology Azienda Ospedaliero Universitaria Careggi, Florence, Italy, Philip B. Gorelick, MD, MPH, Professor of Translational Science and Molecular Medicine, Michigan State University College of Human Medicine, Medical Director, Hauenstein Neuroscience Center, Mercy Health at Saint Mary's, Grand Rapids, MI, USA.
  • 2001 ScienceDirect
    R. Loch Macdonald, Bryce Weir.
    Also available: Print – 2001
  • 2005 Thieme eNeurosurgery
    [edited by] R. Loch MacDonald.
  • 2013 Springer
    Mario Zuccarello, Joseph F. Clark, Gail Pyne-Geithman, Norberto Andaluz, Jed A. Hartings, Opeolu M. Adeoye, editors.
    The book contains 48 articles presented at the 11th International Conference on Cerebral Vasospasm held in Cincinnati, Ohio, USA, in July 2011. This collection of papers represents a cross-section of the enormous progress that has been made towards a thorough understanding and effective treatment of neurovascular events following aneurysmal subarachnoid hemorrhage, including cerebral vasospasm. It is of interest to clinicians who wish to apply state-of-the-art knowledge to their management of this devastating condition and to basic scientists wishing to expand their understanding of cerebrovascular and neural pathophysiology related to subarachnoid hemorrhage.
  • 2008 Springer
    edited by T. Kırış and J.H. Zhang.
    Also available: Print – 2008
  • 2005/2006
    Matthew Phillip Kirschen.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Florian Deisenhammer, Finn Sellebjerg, Charlotte E Teunissen, Hayrettin Tumani, editors.
    The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laboratory methods. By combining different CSF parameters, a wide range of diagnostic entities can be identified. However, properly interpreting the test results requires a high level of expertise and cannot be achieved by just reporting on individual analytic values. This book covers essential aspects of cerebrospinal fluid analysis and its use in the diagnosis of common neurological diseases. The first part addresses preclinical aspects such as the history of CSF, as well as the anatomical, physiological, and biological background of this valuable fluid. In addition, CSF collection, its preanalytical and methodological implications, and the increasing number of disease-specific markers in CSF are discussed in detail. Lastly, CSF analyses are put into context with clinical syndromes, demonstrating their diagnostic value in neurological clinical practice. Cerebrospinal Fluid in Clinical Neurology helps readers understand the preanalytical and analytical aspects of CSF diagnostics and offers a valuable reference guide for interpreting CSF results during the clinical work-up for neurological patients.
  • 2009
    [edited by] David N. Irani.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer Protocols
    edited by Daniel Keppler, Athena W. Lin.
    Evolution and classification of oncogenic human papillomavirus types and variants associated with cervical cancer / Zigui Chen, Luciana Bueno de Freitas, and Robert D. Burk -- Real-time PCR approach based on SPF10 primers and the INNO-LiPA HPV genotyping extra assay for the detection and typing of human papillomavirus / M. Isabel Micalessi, Gaëlle A. Boulet, and Johannes Bogers -- Replication of human papillomavirus in culture / Eric J. Ryndock, Jennifer Biryukov, and Craig Meyers -- HPV binding assay to laminin-332/integrin [alpha]6[beta]4 on human keratinocytes / Sarah A. Brendle and Neil D. Christensen -- Methods to assess the nucleocytoplasmic shuttling of the HPV E1 helicase and its effects on cellular proliferation and induction of a DNA damage response / Michaël Lehoux, Amélie Fradet-Turcotte, and Jacques Archambault -- Genetic methods for studying the role of viral oncogenes in the HPV life cycle / Jason M. Bodily -- Robust HPV-18 production in organotypic cultures of primary human keratinocytes / Hsu-Kun Wang, Thomas R. Broker, and Louise T. Chow -- High-throughput cellular assay to quantify the p53- degradation activity of E6 from different human papillomavirus types / David Gagnon and Jacques Archambault -- Retroviral expression of human cystatin genes in HeLa cells / Crystal M. Diep, Gagandeep Kaur, Daniel Keppler, and Athena W. Lin -- Molecular analysis of human papillomavirus virus-like particle activated langerhans cells in vitro / Andrew W. Woodham, Adam W. Woodham, Adam B. Raff, Diane M. Da Silva, and W. Martin Kast -- Selective silencing of gene target expression by siRNA expression plasmids in human cervical cancer cells / Oscar Peralta-Zaragoza [and eleven others] -- Silencing of E6/E7 expression in cervical cancer stem- like cells / Wenyi Gu, Nigel McMillan, and Chengzhong Yu -- Two-step procedure for evaluating experimentally induced DNA damage : texas red and comet assays / Gina J. Ferris, Lauren B. Shunkwiler, and Charles A. Kunos -- Measurement of deubiquitinating enzyme Activity via a suicidal HA-Ub-VS probe / Colleen Rivard and Martina Bazzaro -- Immunocytochemical analysis of the cervical pap smear / Terry K. Morgan and Michelle Berlin -- Diagnosis of HPV-negative, gastric-type adenocarcinoma of the endocervix / Edyta C. Pirog -- Targeting of the HPV-16 E7 protein by RNA aptamers / Julia Dolores Toscano-Garibay, María Luisa Benítez-Hess, and Luis Marat Alvarez-Salas -- Use of MYBL2 as a novel candidate biomarker of cervical cancer / Cara M. Martin [and others] -- Fixation methods for the preservation of morphology, RNAs, and proteins in paraffin-Embedded human cervical cancer cell xenografts in mice / Yoko Matsuda and Toshiyuki Ishiwata -- Assessment of the HPV DNA methylation status in cervical lesions / Mina Kalantari and Hans-Ulrich Bernard -- MeDIP-on-chip for methylation profiling / Yaw-Wen Hsu, Rui-Lan Huang, and Hung-Cheng Lai -- Use of DBD-FISH for the study of cervical cancer progression / Elva I. Cortés-Gutiérrez [and four others] -- Quantitative and high-throughput assay of human papillomavirus DNA replication / David Gagnon, Amélie Fradet-Turcotte, and Jacques Archambault -- Native human papillomavirus production, quantification, and infectivity analysis / Jennifer Biryukov, Linda Cruz, Eric J. Ryndock, and Craig Meyers -- Functional analysis of HPV-like particle-activated langerhans cells in vitro / Lisa Yan, Andrew W. Woodham, Diane M. Da Silva, and W. Martin Kast -- Assessment of the radiation sensitivity of cervical cancer cell lines / Mayil Vahanan Bose and Thangarajan Rajkumar -- Mouse model of cervicovaginal papillomavirus infection / Nicolas Çuburu, Rebecca J. Cevio, Cynthia D. Thompson, and Patricia M. Day -- Establishment of orthotopic primary cervix cancer xenografts / Naz Chaudary, Karolina Jaluba, Melania Pintilie, and Richard P. Hill -- Generation of K14-E7/[delta]N87[beta] cat double transgenic mice as a model of cervical cancer / Gülay Bulut and Aykut Üren.
  • NGC
  • 2016 Springer
    Pier Paolo Maria Menchetti, editor.
    Anatomy of cervical spine -- Biomechanical evaluation of cervical spine Imaging -- Anesthesiology procedures involved on cervical spine -- Pain management of cervical spine disease -- Percutaneous procedures in cervical disc herniation treatment -- Endoscopy in cervical spine surgery -- Percutaneous posterior facet augmentation in cervical foraminal stenosis -- Anterior cervical decompression and fusion -- Anterior approach and autologous interbody fusion -- Role of cages in anterior cervical surgery -- Cervical prosthetic discs -- Role of materials in cervical spine fusion -- Biomechanical engineering in choice of different stiffness material -- C1-C2 posterior approach -- Screwing of the dens epistropheus -- Transarticular posterior screw fixation -- Posterior open door approach -- Vertebral compression fracture on cervical spine -- Corpectomy in cervical bone metastasis -- Trigeminal neuralgia surgery -- Robotics in cervical spine surgery -- Postoperative physical therapy rehabilitation.
  • 2008 Thieme eNeurosurgery
    [edited by] Todd J. Albert, Joon Yung Lee, Moe R. Lim.
    Presents a focused and succinct review of surgical cervical spine cases, representing mid to high-level complexity, with preferred management methods, including a rationale of pros and cons of alternative methods. A quick, clear, and practical approach to diagnosis and surgical management of cervical problems of the spine. The diagnosis-based format proceeds logically to the specific and most up-to-date methods of treatment.
  • 2012 Ovid
    [edited by] Edward C. Benzel.
    "This is the most comprehensive spine resource available. It is authored by members of the Cervical Spine Research Society, which is the premier society dealing with cervical spine problems. Cervical spine problems are treated by both neurosurgeons and orthopaedic surgeons. We will have a corresponding web site that will contain the book content plus the basic science content and videos of procedures with some updates"--Provided by publisher.
  • 2009
    by Edwin A. Bowman, Jr.
    Cesarean hysterectomy: an analysis of one thousand consecutive operations -- Additional statistics for elective cesarean hysterectomy -- Additional statistics for emergency cesarean hysterectomy -- Miscellaneous statistics -- Urinary tract injuries at time of cesarean hysterectomy -- Cesarean hysterectomy and cancer -- Maternal deaths -- Early history of cesarean hysterectomy.
  • 2009 Springer
    contributors, L.K. Antos ... [et al.] ; Harald H.H.W. Schmidt, Franz Hofmann, Johannes-Peter Stasch, editors.
  • [prepared by the Dept. of Health and Human Services for the Domestic Policy Council].
  • 2013 Springer
    John Geigert.
    An effective CMC regulatory compliance strategy for biologics and biopharmaceuticals can seem like a mystery. Through means of this 2nd edition, this no longer needs to occur. A great deal of thanks goes to two regulatory authorities - the United States Food and Drug Administration (FDA) and the European Medicines Agency (EMA), who provide through their respective websites, an abundance of guidance, especially in the last several years. So much has changed since the 1st edition of this book was published in 2004. There are now additional manufacturing processes for producing commercial biopharmaceuticals - transgenic plant cell cultures and transgenic animals. In addition to commercial recombinant proteins and monoclonal antibodies, there are now commercial cell-based medicines (cellular therapy) and DNA-based medicines (gene therapy). Biosimilars are now on the marketplace in Europe, and under review for commercial approval in the USA. Vaccine manufacturing has resurged due to the concerns of potentially pandemic mutated animal influenzas (e.g., swine flu, bird flu). Strategic international regulatory guidances have been adopted that are driving the entire pharmaceutical industry, including biopharmaceuticals, to a higher standard of performance, including Quality by Design (QbD), Quality Risk Management (QRM) and Pharmaceutical Quality Systems (PQS). The vast majority of the over 600 regulatory references listed in this book were either issued or updated since the release of the 1st edition. All of these changes are the reason this updated edition includes not only biopharmaceuticals but also other biologics (e.g., live virus vaccines, human plasma-derived proteins, cell-based medicines, natural-sourced proteins) that have CMC regulatory compliance concerns and challenges in common with the genetically-engineered biologics (i.e., the biopharmaceuticals).
  • 2010 Springer
    Avigdor Schafferman, Arie Ordentlich, Baruch Velan, editors.
    The Anthrax Capsule: Role in Pathogenesis and Target for Vaccines and Therapeutics / Arthur M. Friedlander -- Proteomic Studies of Bacillus anthracis Reveal In Vitro CO2-Modulation and Expression During Infection of Extracellular Proteases / Theodor Chitlaru, Orit Gat, Galia Zaide, Haim Grosfeld and Izhak Inbar, et al. -- Dynamics of Bacillus anthracis Infection and Control Mechanisms / Pierre L. Goossens, Ian J. Glomski, Lhousseine Touqui and Michèle Mock -- Survival and Trafficking of Yersinia pestis in Non-acidified Phagosomes in Murine Macrophages / James B. Bliska -- The Inverse Relationship Between Cytotoxicity of Y. pestis and Its Virulence / Emanuelle Mamroud, Avital Tidhar, Yinon Levy, Erez Bar-Haim and Gideon Halperin, et al. -- The NlpD Lipoprotein of Yersinia pestis is Essential for Cell Separation and Virulence / Avital Tidhar, Yehuda Flashner, Sara Cohen, Yinon Levy and Ayelet Zauberman, et al. -- Dissection of the Functions of the IglC Protein of Francisella tularensis / Jeanette E. Bröms, Moa Lavander and Anders Sjöstedt -- Yersinia pestis Lipopolysaccharide in Host-Pathogen Interactions / Andrey P. Anisimov, Svetlana V. Dentovskaya, Anna N. Kondakova, Buko Lindner and Rima Z. Shaikhutdinova, et al. -- The Interactions Between Pathogens and Dendritic Cells: From Paralysis of Cells to Their Recruitment for Bacterial Colonization / Baruch Velan, Erez Bar-Haim, Gal Markel, Hila Cohen and Ayelet Zauberman, et al. -- Comparative Approaches to Identify Host Factors Specifically Targeted by Yersinia pestis During the Infectious Process / Françoise Guinet, Patrick Avé, Louis Jones, Michel Huerre and Elisabeth Carniel -- Poxvirus Entry into Host Cells / Bernard Moss, Zain Bengali, Himani Bisht, Jason P. Laliberte and P.S. Satheskumar -- Role of A33R Amino-Acid 118L in the Interactions of Vaccinia Virus with the Host / Nir Paran, Shlomo Lustig, Anat Zvi, Tomer Israely and Sharon Melamed, et al. -- Inhibitors of Innate Immunity from Vaccinia Virus / Geoffrey L. Smith -- Brucella Species Synchronize Their Life Cycle to the Gestation Cycle of Their Ruminant Hosts / Svetlana Bardenstein and Menachem Banai -- MMP-9 as a Marker for Vaccinia Virus Related Encephalitis / Tomer Israely, Sharon Melamed, Noam Erez, Boaz Politi and Udy Olshevsky, et al. -- Epidemic Cowpox Virus Infections in Germany / Andreas Kurth and Andreas Nitsche -- The Two Partner Secretion Transporters of Yersinia pestis: Cloning, Immunogenicity and In Vivo Expression Following Airway Infection / Yinon Levy, Anat Zvi, Haim Grosfeld, Avital Tidhar and David Gur, et al. -- Genetic Detection of Vesicle Forming Pathogens by Arrayed Primer Extension (APEX) / Adi Beth-Din, Ofir Israeli, Ohad Shifman, Dana Stein and Einat Ben-Arie, et al. -- Subtyping Biothreat Bacterial Pathogens / Paul Keim and Talima Pearson -- A Rapid Method for Bacillus anthracis Genotyping / Haim Levy, Morly Fisher, Naomi Ariel, Shay Weiss and Anat Zvi, et al. -- Tularemia - A Disease with an Uncertain Impact on Public Health / Roland Grunow, Daniela Jacob, Andrea Kühn and Herbert Nattermann -- Consequences of Antibiotic Treatment of Francisella tularensis Airways Infections / Erez Bar-Haim, Hila Cohen, Raphael Ber, Ofer Cohen and Avigdor Shafferman -- Novel Live Vaccine Candidates Against Airborne Francisella tularensis / Wayne Conlan and Anders Sjöstedt -- Effect of Disruption of mglA on the Virulence and Immunogenicity of the Francisella tularensis Live Vaccine Strain (LVS) / Ofer Cohen, Galia Zaide, Erez Bar-Haim, Itai Mendelson and Orit Gat, et al. -- Data Mining, Bioinformatic and Immunoinformatic Analyses of Francisella tularensis Schu S4 Genome in Search for Novel Vaccine Candidates / Anat Zvi, Naomi Ariel and Avigdor Shafferman -- Modified Vaccinia Virus Ankara (MVA) based Vaccines - Immunostimulatory and Protective Capacity / Michael H. Lehmann, Melanie Kremer, Yasemin Suezer and Gerd Sutter -- Therapeutic Potential of Vaccinia Hyper Immune Sera in Mouse Models of Lethal Orthopoxviruses Infection / Sharon Melamed, Nir Paran, Tomer Israely, Noam Erez and Shaul Reuveny, et al. -- A Live Plaque Vaccine Candidate with Improved Safety and Immunogenecity / V.A. Feodorova, L.N. Pan'kina, E.P. Savostina, O.S. Kuznetsov and N.P. Konnov, et al. -- Protection Against Plague Afforded by Treatment with Polyclonal αLcrV and αF1 Antibodies / Yinon Levy, Yehuda Flashner, Ayelet Zauberman, Avital Tidhar and Moshe Aftalion, et al. -- Combination of Anthrax-Toxin Neutralizing Antibodies: Analysis of Synergism/Antagonism Effect / Ohad Mazor, Einat Ben-Arie, Adva Mechaly, Ronit Rosenfeld and Hadar Marcus, et al. -- The Efficacy of Antibiotic Treatment to Cure Guinea Pigs Intranasally Infected with Bacillus anthracis Spores / Zeev Altboum, Haim Levy, Shay Weiss, Avi Pass and Nili Rothschild, et al. -- Reverse Vaccinology in Bacillus anthracis / Avigdor Shafferman, Orit Gat, Naomi Ariel, Theodor Chitlaru and Haim Grosfeld, et al.
  • 2013 Springer
    Larry J. Anderson, Barney S. Graham, editors.
    Part I. Virology, pathogenesis, and clinical and epidemiological features of disease -- Part II. Host response to infection and genetics of disease -- Part III. Vaccine platforms and treatment options -- Part IV. Animal and tissue culture models of infection -- Part V. Conclusions -- Index.
  • 2007 NAP
    Leslie Pray and Sally Robinson, rapporteurs ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies.
  • 2013 Springer
    I. W. Fong, editor.
    "This new volume ... aims to address demands and challenges that various infections present to the world at large ('global challenges'), such as the HIV pandemic, continuous threat of spreading common multiresistant pathogenic bacteria, multidrug and extensive drug-resistant tuberculosis, and the influence we can expect on these epidemics with global climate change and international urbanization ... Chapters on these various topics authored by world-renowned experts on these areas provide state-of-the-art reviews on epidemiology, biology, clinical aspects, prevention, current approaches to control, and prevention such as new vaccines, and reassessment of past and present methods are discussed"--Preface.
  • 2008 Springer
    edited by Malgorzata K. Sneve, Mikhail F. Kiselev.
  • 2010 Springer
    Massoud Mahmoudi, editor.
    pt. 1. Urticaria and angiodema -- pt. 2. Skin manifestation of drug allergy -- pt. 3. Allergic contact dermatitis -- pt. 4. Other allergies affecting skin and mucous membranes -- pt. 5. Immunologic diseases of the skin.
  • 2009 Springer
    Massoud Mahmoudi, editor.
    Rhinitis -- Chronic rhinosinusitis -- Allergic diseases of the eye -- Urticaria and angioedema -- Allergic contact dermatitis -- Hypersensitivity pneumonitis -- Atopic dermatitis -- Food allergy -- Drug allergy -- Anaphylaxis -- Eosinophilia and eosinophilic disorder -- Occupational asthma -- Asthma conundrums -- Mastocytosis -- Allergic bronchopulmonary aspergillosis -- HIV/AIDS and complications -- Disorders of immune regulation -- Autoimmune diseases -- Immune-mediated rheumatic diseases -- Immunodeficiency.
  • 2013 Springer
    Mohammad Ali El-Darouti.
    Challenging Cases in Dermatology provides a strategic and analytic way of thinking about unusual dermatologic presentations. Every case presented within this book is a unique story, but the clinical decision pathways used to reach an appropriate solution are similar. A wide range of cases are covered including many extremely rare diseases and rare presentations of diseases that are not, themselves, uncommon. A familiarity with such unusual cases will provide the dermatologist with increased knowledge, a wider perspective, and innovative techniques that can be used to solve diagnostic dilemmas.The author has used his vast experience in practicing dermatology to create a visual reference for skin disease, with the emphasis on working through each case as presented, starting with the clinical data, histological slides, and other available investigations. Each chapter includes a brief discussion of each extraordinary case and includes epidemiology, pathogenesis, clinical and histological features, differential diagnosis, definite diagnosis, prognosis, and management.
  • 2015 Thieme-Connect
    Juergen Freyschmidt ; translator, Terry C. Telger.
  • 2012 Springer
    edited by Massoud Mahmoudi.
    From acute respiratory diseases to chronic lung conditions, pulmonology is a vital area of clinical medicine. Due to a wide array of respiratory diseases, clinical presentation of pulmonary conditions can be complex and oftentimes challenging. In addition to recognizing common characteristics of lung diseases, identifying unusual clinical presentation of pulmonary conditions remains an important educational experience. This concise and easy-to-read title provides that experience in practical context, using a case-based system of learning where a unique case is presented and discussed and questions are provided to challenge the learner and reinforce the transmission of knowledge. Challenging Cases in Pulmonology is not an exhaustive review but rather focuses on common and important problems, with emphasis on evaluation and treatment. The book offers 16 chapters consisting of two or more cases followed by five to ten multiple choice questions. A valuable resource for pulmonologists, allergists, primary care physicians, internal medicine, fellows in allergy and pulmonology, and residents in training, this practical title will also be of interest to nurses, physician assistants, and medical students studying pulmonology. Challenging Cases in Pulmonology complements two previously published case-based titles edited by Dr. Mahmoudi: Challenging Cases in Allergy and Immunology (Humana Press, 2009) and Challenging Cases in Allergic and Immunologic Diseases of the Skin (Springer, 2010).
  • 2013 Springer
    Massoud Mahmoudi, editor.
  • 2006 Thieme eNeurosurgery
    Muwaffak Abdulhak, Shaden Marzouk.
    Odontoid fracture type I -- Transodontoid screw for type II odontoid fracture -- Nonunion of a type II odontoid fracture -- Atlantoaxial instability -- Bilateral locked facets -- Cervical kyphosis -- Spinal trauma -- Ankylosing spondylitis -- Esophageal injury -- Traumatic thoracic fracture -- Lumbar fracture -- Burst fracture -- Traumatic lumbar fracture -- Multiple burst fractures -- Sacral fracture / Rahul Vaidya and Marilyn Gates -- Atlanto-occipital dislocation / Eric Spickler -- Cranial settling -- Rheumatoid arthritis -- Rheumatoid patient with ventral cord compression -- Rheumatoid arthritis with instability -- Percutaneous cervical decompression -- Cervical cages -- Mechanical neck pain -- Multilevel anterior cervical discectomy and fusion (ACDF) -- Hardware failure -- Postoperative kyphosis -- Multilevel cervical stenosis -- Ossification of the posterior longitudinal ligament (OPLL) -- Cervical myelopathy -- Cervical hardware failure -- Central cord with osteoporosis -- Pseudomeningocele -- Angioedema -- Thoracic disc -- Syrinx -- Transverse myelitis -- Discogenic back pain -- Adjacent segment disease -- Motion preservation technology -- Percutaneous lumbar laminotomies and foraminotomies -- Large disc herniation treated percutaneously -- Segmental instability -- Lumbar instability and radiculopathy -- Foot drop -- Pars defect -- High-grade spondylolisthesis -- Multilevel posterior lumbar interbody fusion -- Bone morphogenetic protein -- Degenerative scoliosis -- Nerve root impingement by pedicle screw -- Lumbar scoliosis -- Degenerative lumbar spine disease with segmental instability -- Lumbar nonunion -- Mechanical back with previous posterior fusion -- Osteoporosis -- Metastatic lesion -- Plasmacytoma with postembolization swelling -- Thoracic tumor -- Thoracolumbar instrumentation failure -- Thoracic screw misplacement -- Recurrent giant cell tumor -- Lumbosacral giant cell tumor with segmental instability -- Large upper cervical nerve sheath tumor -- Benign thoracic tumor -- Spinal tumor / Asim Mahmood -- Lumbar schwannoma -- Metastatic spinal cord lesion -- Sacral lesion -- Recurrent sacral tumor -- Spinal epidural abscess -- Thoracic osteomyelitis -- Pott's disease -- Intramedullary cervical lesion -- Klippel-Feil spine -- Klippel-Feil Syndrome -- Cervical rib -- Ankylosing hyperostosis of Forestier and Rotes-Querol -- Fibrous dysplasia -- Diastematomyelia -- Spinal teratoma -- Congenital abnormality of the spine -- Thoracic arteriovenous fistula -- Arachnoid cyst -- Achondroplasia -- Arachnoiditis -- Spinal deformity -- Tethered cord.
  • 2010
    edited by Andrew R. Houghton and David Gray.
    Status: Not Checked OutLane Catalog Record
    Section A. The basics. -- 1. Taking a history -- 2. An approach to the physical examination -- 3. Devising a different diagnosis -- 4. Ordering basic investigations -- 5. Medical records -- 6. Presenting cases -- Section B. Individual systems. -- 7. The cardiovascular system -- 8. The respiratory system -- 9. The gastrointestinal system -- 10. The renal system -- 11. The genitourinary system -- 12. The nervous system -- 13. Psychiatric assessment -- 14. The musculoskeletal system -- 15. The endocrine system -- 16. The breast -- 17. The haematological system -- 18. Skin, nails and hair -- 19. The eye -- 20. Ear, nose and throat -- 21. Infectious and tropical diseases -- Section C. Special situations. -- 22. Assessment of the newborn, infants and children -- 23. The acutely ill patient -- 24. The patient with impaired consciousness -- 25. The older patient -- 26. Death and the dying patient.
  • 2005 CRCnetBASE
    edited by Rolf Franke and Heinz Schilcher.
  • 2014 CRCnetBASE
    Moumita Das.
    1. Introduction to chamomile -- 2. Chamomile : botany -- 3. Chamomile : medicinal properties -- 4. Chamomile oil and extract : localization, chemical composition, extraction, and identification -- 5. Genetics and breeding of chamomile -- 6. Cultivation of chamomile -- 7. Chamomile : patents and products.
  • 2011
    Jeremy J. Shen.
    In this thesis, we present advancements in some change-point problems and their applications to genomic problems that arises from massively parallel sequencing. Change-point problems are concerned with abrupt changes in the generating distribution of a stochastic process evolving over time, space, or any ordered set. This thesis focuses on a number of change-point models and inference problems on point processes. We provide a change-point model and efficient algorithms to detect change-points in relative intensity of non-homogeneous Poisson processes. A model selection approach is constructed in the spirit of classical Baysian Information Criterion, but tailored to the irregularity of change-point problems. We review an array of inference problems surrounding the change-point construct; and propose a point-wise Bayesian credible interval for the parameter of the generating distribution for exponential family. An asymptotic result on the relationship between frequentist and Baysian change-point estimator is shown. We investigate how data characteristics, such as sample size, signal strength, and change-point location, influences the inference procedures through a simulation study. On the application front, modern massively parallel sequencing generates enormous and rich data with much systematic and random noise. We provide a survey of the sequencing technologies and some statistical challenges in various steps of sequencing data analysis. A recent application of sequencing in population and tumor genomics is the profiling of genome copy number and detection of copy number variations across sample. We demonstrate in this thesis that sequencing reads can be viewed naturally as a stochastic process along the genome. Copy number variants are modeled as abrupt jumps in the read