BookYoshio Matsuda, editor.
Summary: This edited book presents the latest information on epidemiology, pathophysiology, diagnosis, therapy, and some current topics covering all aspects of cerebral palsy. It offers a novel interpretation of a group of lifelong movement disorders, which now is an accepted notion that the causes of cerebral palsy are multifactorial rather than birth asphyxia. The book is organized into three parts, and it begins with illustrating the perspective of the disease. Then focuses on the relationship between clinical features of perinatal complications/events and cerebral palsy. The last part offers a hot topic of the prevention and the latest therapy, such as hypothermia, neuroprotection, and stem cell transfer. Since there is no cure for this congenital motor disability of cerebral origin, effective strategies for primary prevention are highly desirable. Effective strategies require an understanding of causal pathways and the Editor wishes to disseminate the experience and knowledge through this comprehensive volume to the readers....
Contents:
Part I Perspective
1 History and Definitions
2 Epidemiology of the Cerebral Palsy
3 Current Status of the Japan Obstetric Compensation System for Cerebral Palsy
4 Clinical Diagnosis of Cerebral Palsy
5 Imaging Findings of Perinatal Brain Lesions that may Cause Cerebral Palsy
Part II Relations of perinatal complications/events to CP
6 Chromosomal Abnormality
7 Morphological Abnormalities Mainly in the Central Nervous System
8 Cytomegalovirus Infection, Toxoplasmosis
9 Herpes Infection
10 Multiple Pregnancy
11 Hypertensive Disorders of Pregnancy
12 Urgent Preterm Labor/Preterm Water Breaking
13 Fetal Growth Restriction/Small for
Dates
14 Cases Probably Considered as Intrauterine Onset
15 Reduced Fetal Movement
16 Placental Abruption
17 Intrauterine Infection/Chorioamnionitis
18 Fetomaternal hemorrhage
19 Cases Associate with Umbilical Cord
20 Intrapartum Hypoxia
21 Uterotonic Agents
22 Assisted Vaginal Delivery (Including Kristeller M
neuver)
23 Prolonged Labor
24 Maternal Respiratory and Circulatory Failure
25 GBS Infection
26 Birth Asphyxia
27 Prematurity
28 Intraventricular Hemorrhage, Periventricular Leu
omalacia
29 Neonatal Stroke
30 Neonatal Hypoglycemia
31 Bilirubin Encephalopathy
32 Apparent Life Threatening Event (ALTE)
Part III Prevention
33 Neonatal Hypothermia
34 Recent Findings on the Perinatal Brain Protective Effects of Magnesium
35 Mechanism and Current Status of Umbilical Cord Blood Stem Cell Transplantation.