BookAhmet Bahadir Ergin, A. Laurence Kennedy, Manjula K. Gupta, Amir H. Hamrahian.
Summary: Developed via a peer review process that included 25 experienced endocrinologists and utilizing the best current evidence, The Cleveland Clinic has created a practical set of protocols for over 25 commonly used dynamic endocrine tests. The cornerstone of clinical endocrinology, these evidence-based protocols play an important role in clinical decision-making and are important element of billing and compliance with high quality standards. Included here are various tests for pituitary and adrenal disorders, thyroid disorders, and glucose metabolism and pancreatic disorders, presented systematically with indications, preparation, materials needed, precautions, procedure, interpretation, and caveats. Filling the gap left by a lack of national guidelines, The Cleveland Clinic Manual of Dynamic Endocrine Testing is an up-to-date practical guide for endocrinologists, nurses, and their staff, inside or outside of the US, who need to perform and interpret dynamic endocrine testing in their everyday practice, as well as medical students, residents and fellows who have interest in endocrinology.
Contents:
Part I: Dynamic Tests in Pituitary/Adrenal Disorders
ACTH Stimulation Test for Adrenal Insufficiency with Total Cortisol Levels
ACTH Stimulation Test for Adrenal Insufficiency with Free Cortisol Levels
ACTH Stimulation Test for Late Onset (Non-classic) 21-Hydroxylase Deficiency
Metyrapone Stimulation Test
Two Day Low Dose Dexamethasone Suppression Test
Combined CRH Dexamethasone Suppression Test
Overnight Low Dose Dexamethasone Suppression Test ? 1 mg
Overnight High Dose Dexamethasone Suppression Test ? 8 mg
Ovine Corticotropin Releasing Hormone (oCRH) Stimulation Test
Insulin Tolerance Test (ITT)
Glucagon Stimulation Test for GHD (GST)
GHRH-Arginine GH Stimulation Test
Growth Hormone Suppression Test (Post-Glucose Administration)
Clonidine Suppression Test for Pheochromocytoma
Intravenous Saline Suppression Test for Evaluation of Primary Aldosteronism
Oral Sodium Loading Test
Captopril Challenge Test
Water Deprivation Test for DI
Part II: Dynamic Tests in Thyroid Disorders
Thyroid Cancer Follow-up: Withdrawal Protocol
Thyroid Cancer Follow-up: Thyrogen Injection with No Scan
Thyroid Cancer Follow-up: Thyrogen Injection with Scan with/without Treatment
Levothyroxine Absorption Test
Part III: Dynamic Tests in Glucose Metabolism/Pancreas Disorders
Seventy-two Hour Fast for Insulinoma
Glucagon Stimulation to Test Beta Cell Reserve
Mixed Meal Hypoglycemia Test
Secretin Stimulation Test for Gastrinoma
Part IV: Invasive Dynamic Endocrine Testing
Inferior Petrosal Sinus Sampling
Adrenal Venous Sampling.