Bookedited by Linda Bogar, April Stempien-Otero.
Summary: This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.
Contents:
Section 1: Historical Background
History of Heart Transplant
Immunosuppression related to transplant
Section 2: Pre-operative evaluation process
Pathophysiology of heart failure
Contraindications to heart transplantation
Psycho-Social considerations
Multi-disciplinary team input
Section 3: Organ Allocation
Current Listing System
Proposed Changes
Matching donor to recipient
Section 4: Organ Procurement
Organ preservation
The donor operation
Ex Vivo perfusion
Section 5: Transplant Operation
Surgical techniques
Surgical Complications
Section 6: Anesthesia Management
Anesthesia techniques for heart transplant
Section 7: Post-operative ICU and hospital management
Ventilator management
Weaning of inotropes
Imaging studies and laboratory testing
Physical and Occupational therapy
Section 8: Transplant Immunology
Induction and maintenance agents
Complication of immunosuppression
Rejection
Section9: Long term outpatient management of the heart transplant patient
Chronic immunosuppression medications
Infection prophylaxis
Monitoring for rejection
Section 10: Mechanical Support of the pre-transplant patient
ECMO
LVAD support
Section 11: The Contemporary successful Heart transplant program
Regulatory agencies
Quality measures
The financial aspect of the heart transplant program
The multi-disciplinary approach
Administrative support of the program
Section 12: Special Topics
Re-transplantation
Combined Heart transplant with other organ transplantation
Section 13,Outcomes Data
Survival data
Quality of life
Chronic rejection
Malignancy after transplant
Section 14: The future of heart transplantation
Advances in immunosuppression
Stem cell therapy
DCD donor use
Will we still be doing heart transplants in 10 years.