BookMario Milco D'Elios, Cosima Tatiana Baldari, Francesco Annunziato, editors ; foreword by Donatella Lippi.
Summary: This volume of the series Rare Diseases of the Immune System presents detailed state of the art knowledge on the cellular primary immunodeficiencies; it includes extensive coverage of both basic science discoveries and the latest clinical advances in the field. The book is structured in accordance with the most recent classification of PIDs and also covers updates on the T cell immunological synapse. Readers will find comprehensive, in-depth descriptions of novel cellular PID genes and related clinical applications, mucosal T cells, and the various clinical phenotypes of cellular PIDs. Cellular Primary Immunodeficiencies will be of high value for immunologists, pediatricians, rheumatologists, oncologists, internists, and infectious disease specialists and will also be informative for MD, Master and PhD students.
Contents:
1. Primary Immunodeficiencies
2. Genetics of Cellular Immunodeficiencies
3. Phenocopies of Primary Immuno Deficiencies
4. Dysfunctional immune synapses in T cell immunodeficiencies
5. Mucosal immunity in primary immunodeficiencies
6. Combined Immuno Deficiencies
7. Congenital defects of phagocytes
8. Defects in intrinsic and innate immunity
9. Diseases of immune dysregulation
10. IPEX syndrome and IPEX-related disorders
11. Autoinflammatory disorders
12. Lung in Cellular Immunodeficiencies
13. Gut involvement in Cellular Immunodeficencies
14. Malignancies in Cellular Immunodeficencies
15. Autoimmunity in Cellular Immunodeficencies
16. Differential diagnostic in Cellular Immunodeficiencies
17. Management of Cellular Immunodeficiencies
18. Vaccines in Cellular Immunodeficiencies
19. Gene therapy in Cellular Immunodeficiencies.