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  • T cell protocols. 2nd ed. 2009
    Springer Protocols
    Analysis of frequency and phenotype of antigen-specific T cells / Angus Stock and Vincenzo Cerundolo -- B cell helper assays / Sergio Abrignani, ... [et al.] -- Transkingdom RNA interference (tkRNAi) / Thu A. Nguyen and Johannes H. Fruehauf -- Flow cytometry and cell activation / Sonia Gavasso -- Investigating T cells by polychromatic flow cytometry / Enrico Lugli, Leonarda Troiano, and Andrea Cossarizza -- Generation of human T cell clones / Sabrina Mariotti and Roberto Nisini -- Limiting dilution analysis of antigen-specific T cells / Jorge Carneiro, Lurdes Duarte, and Elisabetta Padovan -- T cell epitope-mapping by cytokine gene expression assay / Maurizio Provengano and Giulio C. Spagnoli -- Cytokine multiplex immunoassay / Wilco de Jager, Berent Prakken, and Ger T. Rijkers -- Purification of the T cell antigen receptor and analysis by blue-native PAGE / Mahima Swamy and Wolfgang W.A. Schamel -- Non-replicating recombinant vaccinia virus expressing CD80 to enhance T-cell stimulation / Paul Zajac.
  • Overview of orchestration of CD4+ T cell subsets in immune responses -- Th1/Th2 cell differentiation and molecular signals -- Th1/Th2 cell?s function in immune system -- Regulatory T Cell differentiation and their function in immune regulation -- Th17 differentiation and their pro-inflammation function -- Tfh Cell differentiation and their function in promoting B cell responses -- Differentiation, Regulation and Function of Th9 Cell -- The biology and functions of Th22 cell.
  • This book summarizes the state-of-the art in the development of T cell-based in vitro assays, which offer useful tools for hazard identification, risk assessment and improvement of diagnostics. It will be of interest to scientists, the chemical and pharmaceutical industry, and regulators involved in the replacement of animal testing methods. The identification of hazardous chemicals and drugs is essential to ensuring human health. The ban on animal testing for the cosmetics industry since 2009 and international efforts to reduce and replace animal testing in research and immunotoxicology call for alternative in vitro methods. The most specific immune response to chemicals and drugs that cause allergic contact dermatitis, respiratory disease and adverse drug reactions is the highly antigen-specific T lymphocyte response. Therefore the use of T cells as tools for identifying contact allergens and drugs that may cause health problems is of great interest.
  • T-cell lymphomas 2013
    The mature T and NK cell lymphomas are rare, comprising approximately 10% of all malignant lymphomas. The incidence of T-cell lymphoma is variable around the world, with a higher incidence compared to B-cell lymphomas in the Asian basin. While the overall incidence of B-cell lymphomas has begun to decline in the United States, the incidence of T-cell lymphomas continues to rise. Over the last decade, a number of novel agents have been developed which target T-cell lymphomas and studies have identified novel genes and pathways associated with lymphomagenesis in T-cells. This comprehensive volume examines the clinical and biological aspects of the T-cell lymphoproliferative disorders in adults and children. The book includes an overview of both the cutaneous and the systemic T-cell malignancies and addresses the classification of T-cell lymphomas, the clinical features of each subtype, and the relevant molecular and genetic studies. Clinical outcomes and treatment strategies are discussed with an emphasis on the development of novel biological and targeted therapies. An outstanding resource for hematologists and oncologists, this book gathers insights from experts in the field and provides the most up-to-date information on all of the T-cell lymphoma subgroups and current and emerging therapies.
  • Continuing the tradition of excellence that began in 1972, this latest edition of Tachdjian's Pediatric Orthopaedics offers the detailed visual guidance and unmatched expertise you need to effectively diagnose and treat pediatric musculoskeletal disorders. Extensive updates offer you the latest knowledge on etiology, imaging, differential diagnosis, and non-operative and surgical techniques for a wide range of pediatric orthopaedic conditions. Access expert guidance on difficult diagnostic and clinical management issues for your most challenging cases. Perfect your technique with the visual guidance of nearly 2,500 full-color illustrations and 60 videos of pediatric surgical procedures, including a number that highlight clinical examination and unusual clinical findings.
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  • Temporal characteristics of foot movement in tai chi exercise / Hong, Y., Mao, D.W., Lia, J.X. -- The exercise intensity of tai chi chuan / Lan, C., Chen, S.-Y., Lai, J.-S. -- Tai chi exercise and muscle strength and endurance in older people / Xu, D.Q., Hong, Y., Li, J.X. -- Muscle action pattern and knee extensor strength of older tai chi exercisers / Wu, G. -- The effectiveness of tai chi exercise in improving aerobic capacity : an updated meta-analysis / Taylor-Piliae, R.E. -- Tai chi exercise in improving cardiorespiratory capacity / Thornton, E.W. -- Effects of a traditional taiji/qigong curriculum on older adults' immune response to influenza vaccine / Yang, Y. ... [et al.] -- Tai chi exercise and proprioception behavior in old people / Li; J.X., Xu, D.Q., Hong, Y. -- Neural mechanisms underlying balance control in tai chi / Gatts, S. -- Sensorimotor control of balance : a tai chi solution for balance disorders in older subjects / Tsang, W.W.N., Hui-Chan, C.W.Y -- Tai chi and balance control / Wong, A.M.K., Lan, C. -- Tai chi and falls prevention in older people / Harmer, P.A., Li, F. -- Tai chi exercise and the improvement of mental and physical health among college students / Wang, Y.T. -- Effect of tai chi on depressive symptoms amongst Chinese older patients with major depression : the role of social support / Chou, K.-L. -- Tai chi exercise and the improvement of health and well-being in older adults / Yau, M.K.-s. -- Teaching tai chi with mindfulness-based stress reduction to middle school children in the inner-city : a review of the literature and approaches / Wall, R.B. -- Tai chi chuan in the management of Parkinson's disease and Alzheimer's disease / Klein, P.J. -- Tai chi training for patients with coronary heart disease / Lan, C. ... [et al.] -- Tai chi exercise in patients with chronic heart failure / Yeh, G.Y., Wayne, P.M., Phillips, R.S. -- Tai chi chuan for breast cancer survivors / Mustian, K.M., Palesh, O.G., Flecksteiner, S.A. -- Tai chi improves pain and functional status in adults with rheumatoid arthritis : results of a pilot single-blinded randomized controlled trial / Wang, C. -- Effects of tai chi exercise on patients with type 2 diabetes / Wang, J.H.
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  • A guide to the iPhone discusses the features of the device, including the iPhone media and the QWERTY keyboard, as well as its e-mail, voicemail, and calendar functions; Internet connectivity and applications; third-party software to enhance the iPhone; iTunes, iBooks, and iPhone games; power user applications; and accessories
  • Introduction : Finding a voice for the spirit -- Spirituality and the holistic approach -- Learning about spirituality in the multi-professional team -- Developing opportunities to talk about spirituality -- Understanding spirituality -- Spiritual care -- Outcomes and opportunities -- Conclusion : the journey continues.
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  • Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years. This monograph, written by V. Craig Jordan - known as the "father of tamoxifen" - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a "failed morning after contraceptive" to become the "gold standard" for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen's pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.
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    Tandem repeat polymorphisms : mediators of genetic plasticity, modulators of biological diversity and dynamic sources of disease susceptibility / Anthony J. Hannan -- Evolution of simple sequence repeats as mutable sites / David G. King -- Single amino acid and trinucleotide repeats : function and evolution / Noel Faux -- Promoter microsatellites as modulators of human gene expression / Sterling M. Sawaya ... [et al.] -- Dynamic mutations : where are they now? / Clare L. Van Eyk and Robert I. Richards -- Unstable mutations in the FMR1 gene and the phenotypes / Danuta Loesch and Randi Hagerman -- Molecular pathways to polyglutamine aggregation / Amy L. Robertson and Stephen P. Bottomley -- Polyglutamine aggregation in Huntington and related diseases / Saskia Polling, Andrew F. Hill and Danny M. Hatters -- Selective neurodegeneration, neuropathology and symptom profiles in Huntington's disease / Henry J. Waldvogel ... [et al.] -- Kennedy's disease : clinical significance of tandem repeats in the androgen receptor / Jeffrey D. Zajac and Mark Ng Tang Fui -- Characterising the neuropathology and neurobehavioural phenotype in Friedreich ataxia : a systematic review / Louise A. Corben ... [et al.] -- Polyalanine tract disorders and neurocognitive phenotypes / Cheryl Shoubridge and Jozef Gecz.
  • Longitudinal imaging and analysis of neurons expressing polyglutamine-expanded proteins / Andrey S. Tsvetkov, D. Michael Ando, and Steven Finkbeiner -- Atomic force microscopy assays for evaluating polyglutamine aggregation in solution and on surfaces / Kathleen A. Burke and Justin Legleiter -- Morphometric analysis of Huntington's disease neurodegeneration in Drosophila / Wan Song ... [et al.] -- Size analysis of polyglutamine protein aggregates using fluorescence detection in an analytical ultracentrifuge / Saskia Polling, Danny M. Hatters, and Yee-Foong Mok -- Method for the incremental expansion of polyglutamine repeats in recombinant proteins / Amy L. Robertson and Stephen P. Bottomley -- Pulse shape analysis (PulSA) to track protein translocalization in cells by flow cytometry : applications for polyglutamine aggregation / Yasmin M. Ramdzan, Rebecca Wood, and Danny M. Hatters -- Characterizing social behavior in genetically targeted mouse models of brain disorders / Emma L. Burrows and Anthony J. Hannan -- PCR amplification and sequence analysis of GC-rich sequences : aristaless-related homeobox example / May H. Tan, Jozef Gécz, and Cheryl Shoubridge -- Challenges of "Sticky" co-immunoprecipitation : polyalanine tract protein-protein interactions / T.R. Mattiske ... [et al.] -- Molecular pathology of polyalanine expansion disorders : new perspectives from mouse models / James N. Hughes and Paul Q. Thomas -- Yeast as a platform to explore polyglutamine toxicity and aggregation / Martin L. Duennwald -- Immuno-based detection assays to quantify distinct mutant huntingtin conformations in biological samples / Gregor P. Lotz and Andreas Weiss -- Modeling and analysis of repeat RNA toxicity in Drosophila / S.E. Samaraweera ... [et al.] -- Analyzing modifiers of protein aggregation in C. elegans by native agarose gel electrophoresis / Mats Holmberg and Ellen A.A. Nollen -- Kinetic analysis of aggregation data / Regina M. Murphy -- Bioinformatics method for identifying Q/N-rich prion-like domains in proteins / Eric D. Ross ... [et al.] -- Detecting soluble polyQ oligomers and investigating their impact on living cells using split-GFP / Patrick Lajoie and Erik Lee Snapp -- Cell biological approaches to investigate polyglutamine-expanded AR metabolism / Lori J. Cooper and Diane E. Merry.
  • v. 2 Springer Protocols
    v. 1. Emerging strategies for targets and biomarker discovery -- v. 2. Emerging molecular targets and treatment options.
  • Macrophage pattern recognition receptors in immunity, homeostasis, and self tolerance / Subhankar Mukhopadhyay, Annette Plüddemann, and Siamon Gordon -- Pattern recognition by toll-like receptors / Stefan Bauer, Thomas Müller, and Svetlana Hamm -- Nod-like receptors : pivotal guardians of the immunological integrity of barrier organs / Philip Rosenstiel and Stefan Schreiber -- Toll-like receptors and nod-like receptors : domain architecture and cellular signalling / Tanja Langefeld ... [et al.] -- Humoral pattern recognition molecules : mannan-binding lectin and ficolins / Steffen Thiel and Mihaela Gadjeva -- Lung surfactant proteins A and D as pattern recognition proteins / Patrick Waters ... [et al.] -- Pattern recognition by pentraxins / Alok Agrawal ... [et al.] -- Target pattern recognition by complement proteins of the classical and alternative pathways / Yu-hoi Kang ... [et al.] -- Pattern recognition in phagocytic clearance of altered self / Yoshinobu Nakanishi, Peter M. Henson and Akiko Shiratsuchi -- Structural basis of pattern recognition by innate immune molecules / Eamon P. McGreal -- Lessons from the fly : pattern recognition in Drosophila melanogaster / Subhamoy Pal and Louisa P. Wu -- Immune recognition of plasmodium-infected erythrocytes / Damien V. Cordery and Britta C. Urban -- Innate immune recognition in tuberculosis infection / Anthony G. Tsolaki.
  • The main objective of this book is to provide radiation oncologists with a clear, up-to-date guide to tumor delineation and contouring of organs at risk. With this in mind, a detailed overview of recent advances in imaging for radiation treatment planning is presented. Novel concepts for target volume delineation are explained, taking into account the innovations in imaging technology. Special attention is paid to the role of the newer imaging modalities, such as positron emission tomography and diffusion and perfusion magnetic resonance imaging. All of the most important tumor entities treated with radiation therapy are covered in the book. Each chapter is devoted to a particular tumor type and has been written by a recognized expert in that topic.
  • This handbook is designed to enable radiation oncologists to appropriately and confidently delineate tumor volumes/fields for conformal radiation therapy, including intensity-modulated radiation therapy (IMRT), in patients with commonly encountered cancers.The orientation of this handbook is entirely practical, in that the focus is on the illustration of clinical target volume (CTV) delineation for each major malignancy. Each chapter provides guidelines and concise knowledge on CTV selection for a particular disease, explains how the anatomy of lymphatic drainage shapes the selection of the target volume, and presents detailed illustrations of volumes, slice by slice, on planning CT images. While the emphasis is on target volume delineation for three-dimensional conformal therapy and IMRT, information is also provided on conventional radiation therapy field setup and planning for certain malignancies for which IMRT is not currently suitable.
  • This textbook is designed to help the busy radiation oncologist to accurately and confidently delineate tumor volumes for conformal radiation therapy (including IMRT). The book provides an atlas of clinical target volumes (CTVs) for commonly encountered cancers, with each chapter illustrating CTV delineation on a slice-by-slice basis, on planning CT images. Common anatomic variants for each tumor are represented in individual illustrations, with annotations highlighting differences in coverage. The anatomy of each site and patterns of lymphatic drainage are discussed, and their influence on the design of CTVs is explained in detail. Utilization of other imaging modalities, including MRI, to delineate volumes is highlighted. Key details of simulation and planning are briefly reviewed. Although the emphasis is on target volume delineation for conformal techniques, information is also provided on conventional radiation field setup and design when IMRT is not suitable.
  • Perspectives : bench to bedside and back / Jennifer Wheler and Razelle Kurzrock -- Targeted therapy in acute myelogenous leukemia / Elihu Estey -- Targeted therapy in breast cancer / Barbara S. Craft and Stacy Moulder -- Targeted therapy in chronic lymphocytic leukemia / Apostolia-Maria Tsimberidou and Michael J. Keating -- Targeted therapy in chronic myeloid leukemia / Elias Jabbour, Jorge Cortes, and Hagop Kantarjian -- Targeted therapy in colorectal cancer / Scott Kopetz -- Targeted therapy in non-small cell lung cancer / David J. Stewart -- Targeted therapy in lymphoma / Amanda Wedgwood and Anas Younes -- Targeted therapy in melanoma / Michael Davies, Sunil Patel, and Kevin B. Kim -- Targeted therapy in multiple myeloma / Yuhong Zhou, Raymond Alexanian, and Micael Wang -- Targeted therapy in myelodysplastic syndrome / Alfonso Quintás-Cardama ... [et al.] -- Targeted therapy in epithelial ovarian cancer / Maurie Markman -- Targeted drug therapy in pancreatic cancer / Don L. Gibbons, Robert A. Wolff, and Gauri Varadhachary -- Targeted therapy in prostate cancer / Amado J. Zurita, John F. Ward, and Jeri Kim -- Targeted therapy in renal cell carcinoma / Eric Jonasch and Nizar Tannir -- Targeted therapy of Sarcoma / Joseph Ludwig and Jonathan C. Trent -- Targeted and functional imaging / Vikas Kundra, Dawid Schellingerhout, and Edward F. Jackson -- Combining targeted therapies / David Hong and Lakshmi Chintala -- Drug development in cancer medicine : challenges for targeted approaches / Luis H. Camacho -- Toward personalized therapy for cancer / Sarah J. Welsh and Garth Powis.
  • Therapeutic potential of targeted drug delivery / Ajit S. Narang and Ram I. Mahato -- Antibody therapies for liver malignancy and transplantation / John M. Luk and Kwong-Fai Wong -- Transferrin receptor-mediated transcytosis in intestinal epithelial cells for gastrointestinal absorption of protein drugs / Nurmamet Amet ... [et al.] -- Ionizing radiation for tumor targeted drug delivery / Roberto Diaz, Li Zhou, and Dennis E. Hallahan -- Recent advances in gene expression and delivery systems / Ravikiran Panakanti and Ram I. Mahato -- Cellular barriers for nucleic acid delivery and targeting / Arto Urtti -- Targeted delivery systems of non-viral nucleic acid-based therapeutics / Ga Yong Shim ... [et al.] -- Delivery and targeting of oligonucleotides and siRNA / Ningning Yang and Ram I. Mahato -- Liposomes for non-viral gene delivery / Jiasheng Tu ... [et al.] -- Delivering the bullet to the right intracellular target : a cellular perspective on drug delivery / Maria Teresa Tarragâo-Trani and Brian Storrie -- Mitochondria-targeted drug delivery / Volkmar Weissig and Gerard G. M. D'Souza -- Site-specific prodrug activation strategies for targeted drug action / Mark D. Erion -- Enzyme-activated prodrug strategies for targeted drug action / Jarkko Rautio ... [et al.] -- Targeting colon and kidney : pathophysiological determinants of design strategy / Ajit S. Narang and Ram I. Mahato -- Principles and practice of pulmonary drug delivery / Vivek Gupta, Chandan Thomas, and Fakhrul Ahsan -- Recent advances in ocular drug delivery : role of transporters, receptors, and nanocarriers / Gyan P. Mishra ... [et al.] -- Injectable polymers for regional drug delivery / Rajendra P. Pawar ... [et al.] -- Polymer-drug conjugates / Lucienne Juillerat-Jeanneret and Feride Cengelli -- Polymer micelles for drug delivery / Sungwon Kim and Kinam Park -- Multifunctional stimuli-responsive nanoparticles for targeted delivery of small and macromolecular therapeutics / Srinivas Ganta, Arun Iyer, and Mansoor Amiji -- Physiological stress responsive gene regulation systems for tissue targeting / Hyun Ah Kim and Minhyung Lee.
  • Introduction: the rationale for the development of targeted drugs in cancer therapy -- Identifying critical signaling molecules for the treatment of cancer -- Tyrosine kinase inhibitors and cancer therapy -- Targeting ERBB receptors in cancer -- Inhibition of the IGF-I receptor for treatment of cancer. Kinase inhibitors and monoclonal anitbodies as alternative approaches -- Inhibition of the TGF-B signaling pathway in tumor cells -- The mammalian target of rapamycin kinase and tumor growth inhibtition -- The ras signalling pathway as a target in cancer therapy -- The mitogen-activated protein kinase pathway for molecular-targeted cancer treatment -- Clinical relevance of tareted interference with Src-mediated signal transduction events.
  • Targeted intraoperative radiotherapy is a major advance in the management of cancer patients and has been attracting massive interest worldwide following publication of the results of an important randomized controlled trial in The Lancet. This textbook is designed to introduce this innovative technology in a comprehensive manner to clinicians dealing with cancer patients. Throughout, the emphasis is on practical aspects, and the text is supported by many excellent illustrations. The editors of the book have extensive experience in targeted intraoperative radiotherapy and include co-directors of the TARGIT Academy, which runs international training courses on the technology in the United Kingdom and Germany. They have brought together multidisciplinary contributors from different centers across the world who have wide experience in the field and whose work has been recognized internationally. It is the editors' hope that this book will succeed in ensuring that targeted intraoperative radiotherapy is used effectively worldwide.
  • "Covering the fundamental concepts of molecular imaging, this work addresses basic principles, disease models, imaging studies in animals, imaging in initial human studies, and the application of molecular imaging in pharmacy and drug discovery. Topics are presented in logical progression, from basic concepts to applications. The text includes examples from human studies with imaging of breast cancer, cardiovascular disease, and neurodegenerative diseases. The book is a valuable tool for readers involved with molecular imaging, biomedical imaging, radiology, medical physics, medicinal chemistry, and pharmacology"--Provided by publisher.
  • "This reference covers clinical and bioengineering aspects of muscle reinnervation, a popular new technique at the boundary of biomedical and rehabilitation engineering and neuroscience. With contributions from pioneers in the field, the book provides a review of muscle reinnervation from a biomedical engineering and clinical perspective. It describes neuroscience and other related neuroprosthetic techniques. A companion website offers a wide range of videos and multimedia material to aid in comprehension and application"--Provided by publisher.
  • Targeted therapies for hepatocellular carcinoma / Luigi Bolondi -- Overview of HCC pathophysiology and drug targets / Liliana Montella & Raffaele Addeo -- Antiangiogenic strategies for the treatment of hepatocellular carcinoma / Chiun Hsu, Ying-Chun Shen & Ann-Lii Cheng -- EGF receptor inhibitors for hepatocellular carcinoma / George Papatsimbas, Christina Chatedaki & Dimitris Zacharoulis -- mTOR inhibitors / Gerhard Treiber & Thomas Wex -- Histone deacetylase inhibitors (epigenetic alterations) / Sergio Valente & Antonello Mai -- Hepatocellular carcinoma therapy : combination is the future / Jean-François Dufour -- Other new targeted therapies / Jairo A. Garcia & Lewis R. Roberts.
  • Targeted therapy for non-small-cell lung cancer / Arun Rajan & Giuseppe Giaccone -- Overview of pathophysiology and drug targets for non-small-cell lung cancer / Anish Thomas, Arun Rajan & Giuseppe Giaccone -- EGFR inhibitors and their use in the treatment of metastatic disease / Cesare Gridelli & Antonio Rossi -- VEGF receptor inhibitors / Ariel Lopez-Chavez & Alan Sandler -- CTLA-4 inhibitor : ipilimumab for the treatment of NSCLC / Julie R. Brahmer -- VEGF receptor inhibitors / Kavitha Ramchandran, Millie Das & Heather Wakelee -- HGFR/MET and ALK inhibitors / Eunice L. Kwak -- Vaccines for lung cancer / Ronan J. Kelly -- Index.
  • Targeted therapy for renal cell carcinoma / Ronald M. Bukowski -- Overview of renal cell carcinoma pathways and drug targets / Bernard Escudier -- mTOR in renal cell cancer: modulator of tumor biology and therapeutic target / Piotr J. Wysocki -- VEGF inhibitors / Toni K. Choueiri & Ali R. Golshayan -- VEGFR/PDGFR inhibitors in RCC / Jean S.Z. Lee & Tim Eisen -- Next-generation immunotherapy: CTLA-4 and PD-1 inhibitors / Daniel Y.C. Heng -- EGF receptor inhibitors / Marine Gross-Goupil & Alain Ravaud -- Cytokines / Alexandra Leary, James M.G. Larkin & Lisa M. Pickering -- Vaccination / Robert J Amato -- Evidence-based therapy of non-clear-cell and sarcomatoid renal cell carcinoma / Elan Diamond, Naveed H. Akhtar, Scott T. Tagawa & David M. Nanus -- Bisphosphonates in renal cell carcinoma: palliation versus antitumor effects / Saby George & Roberto Pili -- Combination therapy and future directions in renal cell carcinoma / Bernard Escudier & Camillo Porta.
  • This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.
  • Resistance to Targeted Therapies As a Result of Mutation(s) in the Target / Alexis B. Cortot and Pasi A. Jänne -- The Dynamics of the Cell Signaling Network; Implications for Targeted Therapies / Daniel Gioeli -- Cancer Signaling Network Analysis by Quantitative Mass Spectrometry / Jason R. Neil and Forest M. White -- Development and Implementation of Array Technologies for Proteomics: Clinical Implications and Applications / Julia D. Wulfkuhle, Menawar Khalil, Joseph C. Watson, Lance A. Liotta and Emanuel F. Petricoin -- Using Phosphoflow® to Study Signaling Events of Subpopulations Resistant to Current Therapies / Omar D. Perez -- Mathematical and Computational Models in Cancer / Sudhir Chowbina, Kevin A. Janes, Shayn M. Peirce and Jason A. Papin -- Somatic Evolution of Acquired Drug Resistance in Cancer / John W. Pepper -- Interrogating Resistance to Targeted Therapy Using Genetically Engineered Mouse Models of Cancer / Edward Gunther -- microRNA: A Potential Therapy Able to Target Multiple Cancer Pathways / Benjamin Kefas and Benjamin W. Purow -- Rational Combination of Targeted Agents to Overcome Cancer Cell Resistance / Yun Dai and Steven Grant.
  • This book provides an unprecedented overview of targeted therapies for acute myeloid leukemias. The volume provides comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Authoritative chapters are written by leading research scientists and clinicians, who explain basic concepts and the clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML. The chapter topics include the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53, and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. In addition, chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells, and leukemia metabolism, provide insight into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies complete the overview of the multi-dimensional therapeutic landscape, where leukemia specialists develop treatment strategies, which are expected to bring forth critical breakthroughs in the field of leukemia.
  • Michael H. Weisman, Michael Weinblatt, James S Louie, and Ronald Van Vollenhoven offer their unique insights into choosing the correct pharmacological and non-pharmacological therapies for your patients. Chapters cover the full breadth of rheumatic diseases, rheumatoid arthritis, lupus, connective tissue diseases, osteoporosis, regional pain disorders, and fibromyalgia. The full-color design presents detailed clinical photographs and treatment algorithms for visual guidance and easy reference. Covers the treatment of pediatric patients as well as adults so that you can properly address the particular needs of any patient you see. Features the guidance and specific recommendations of experts from United States and Europe for a state-of-the-art approach to the variety of treatments currently in use. Displays the clinical manifestations of rheumatic diseases in full color, along with treatment algorithms for easy at-a-glance reference.
  • Conducted electrical weapons: a user's perspective / Greg Meyer -- The scientific history / Robert A. Stratbucker -- Conducted electrical weapons and resolution of use-of-force encounters / Charles Mesloh, Mark Henych, and Ross Wolf -- Nonlethal weapons: the broader context / Peter J. Cuenca and John G. McManus -- Transcutaneous muscle stimulation / James D. Sweeney -- Current flow in the human body / Dorin Panescu and Robert A. Stratbucker -- Animal studies / John G. Webster -- CEW research models: animal and human studies / Theodore C. Chan and Gary M. Vilke -- Cardiac arrhythmias / Derek J. Dosdall and Raymond E. Ideker -- Electrocardiographic effects of the CEW / Jeffrey D. Ho -- Serum and skin effects of CEW application / Jeffrey D. Ho -- Electrocardiographic effects of the CEW / Robert Reardon -- Rhabdomyolysis / Ronald Moscati and Samuel Cloud -- Effects of CEWs on respiration / Donald M. Dawes -- Neuroendocrine effects of CEWs / Donald M. Dawes and Mark W. Kroll -- Electroporation of cardiac and nerve cells / Vadim V. Fedorov, Leonid Livshitz, Geran Kostecki, and Igor R. Efimov -- Eye and head injuries / S. Robert Witherspoon, Andreas K. Lauer, and Jonathan L. Marinaro -- CEW effects with illegal stimulant intoxication / Patrick Tchou -- Alcohol and the CEW / Ronald Moscati and Jeffrey D. Ho -- Conducted electrical weapons and implantible cardiac devices / Subba Reddy Vanga, James L. Vacek. Loren Berenhom and Dhanunjaya R. Lakkireddy -- Risk management and the CEW / Greg Bingham -- The New York City experience / Michael D. White and Justin Ready -- Impact of CEW and other types of force and resistance on officer and suspect injuries / Michael R. Smith, Robert J. Kaminski, Jeffrey Rojek, Geoffrey P. Alpert, and James Mathis -- Field statistics overview / James E. Brewer and Mark W. Kroll -- Sudden in-custody death / Samuel J. Stratton -- Stimulant abuse and sudden cardiac death / Steven B. Karch -- The systemic role of illicit drugs and their toxicology / Joshua Gunn, Michael A. Evans, and M. Scott Kriger -- Excited delirium syndrome / Vincent J. M. Di Maio and Theresa G. Di Maio -- Biochemical brain markers in excited delirium deaths / Deborah C. Mash -- Sudden unexpected death in custody (SUDIC) / Charles V. Wetli -- Legal basics for the CEW -- Science and logic meet the law / Michael A. Brave -- Appendix A: Excited delirium checklist -- Appendix B: Electrocution diagnosis checklist.
  • Central gustatory processing in humans / Small, D.M. -- Modern psychophysics and the assessment of human oral sensation / Snyder, D.J., Prescott, J., Bartoshuk, L.M. -- Postoperative/posttraumatic gustatory dysfunction / Landis, B.N., Lacroix, J.-S. -- Neurological causes of taste disorders / Heckmann, J.G., Lang, C.J.G. -- Toxic effects on gustatory function / Reiter, E.R., DiNardo, L.J., Costanzo, R.M. -- Burning mouth syndrome / Grushka, M., Ching, V., Epstein, J. Nasal anatomy and the sense of smell / Hornung, D.E. -- Transduction and coding / Rawson, N.E., Yee, K.K. -- Smell: central olfactory processing / Gottfried, J.A. -- Structure and function of the vomeronasal organ / Witt, M., Wozniak, W. -- Assessment of olfactory function / Hummel, T., Welge-Lüssen, A. -- Posttraumatic olfactory loss / Costanzo, R.M.C., Miwa, T.M. -- Chronic rhinosinusitis and olfactory dysfunction / Raviv, J.R., Kern, R.C. -- Olfactory disorders following upper respiratory tract infections / Welge-Lüssen, A., Wolfensberger, M. -- Olfaction in neurodegenerative disorder / Hawkes, C. -- Human taste: peripheral anatomy, taste transduction, and coding / Breslin, P.A.S., Huang, L. --
  • Preface -- The tattooed and the social environment. The cultural heritage of tattooing: a brief history -- Epidemiology of tattoos in industrialized countries -- The practise of tattooing. Tattoo machines, needles and utilities -- The technique and craftsmanship of tattooing in the professional tattoo parlour -- Tattoo as art, the drivers behind the fascination and the decision to become tattooed -- Personal records from my tattoo parlour: deep emotions drawn as life-long pictures on the skin's canvas -- Tattooist-customer relationships in a diversified environment of professional tattooists and 'scratchers' -- Tattoos and adverse events. Tattoo complaints and complications: diagnosis and clinical spectrum -- Complications of cosmetic tattoos -- Chronic tattoo reactions cause reduced quality of life equaling cumbersome skin diseases -- Contraindications for tattooing -- Laser tattoo removal, precautions, and unwanted effects -- Nano-scale observations of tattoo pigments in skin by atomic force microscopy -- Manufacturing, materials and properties of marketed tattoo ink stock products. Manufacturing of tattoo ink products today and in future -- The realistic variables underlying true safety in tattoo pigment manufacturing -- Making innovative tattoo ink products with improved safety: possible and impossible ingredients in practical usage -- Tailored surface engineering of pigments by layer-by-layer coating -- Ingredients, chemical analysis and safety of marketed tattoo ink stock products. Chemical purity and toxicology of pigments used in tattoo inks -- Survey on european studies of the chemical characterisation of tattoo ink products and the measurement of potentially harmful ingredients -- Tattoo inks: legislation, pigments, metals and chemical analysis -- The challenges and limitations of chemical analysis of particulate pigments of very low solubility -- Photostability and breakdown products of pigments currently used in tattoo inks -- Carbon black nanoparticles and other problematic constituents of black ink and their potential to harm tattooed humans -- Absorption, distribution, metabolism and excretion of tattoo colorants and ingredients in mouse and man: the known and the unknown -- Towards the limiting of health risks associated with tattooing: whitelists for tattoo pigments and preservatives -- Survey of studies on microbial contamination of marketed tattoo inks -- Regulation of and intervention in the tattoo business. The European landscape of national regulations of tattoo inks and businesses -- Implementation of European Council Resolution ResAP(2008)1 in Italy. National and regional regulation of tattoo practices: diversity and challenges -- EU actions to ensure the safety of tattoos and the protection of consumers -- Surveillance of tattoo-related adverse events by the EU RAPEX System and by national monitoring -- The Amsterdam model for control of tattoo parlours and businesses -- Hygiene standards for tattooists -- Hygiene standards in the tattoo parlour and practices for prevention of infection -- Seamless prevention of adverse events from tattooing: integrated strategy emphasising the customer-tattooist interaction -- Regulation of tattoo ink production and the tattoo business.
  • Taurine 9 2015
    Taurine 9 contains original articles and critical reviews based on the oral and poster presentations of XIX International Taurine Meeting held in Kraków, Poland in May 2014. The purpose of the book is to present current ideas, new avenues and research regarding biological functions and clinical applications of taurine and taurine derivatives. It focuses on all aspects of taurine research including the cardiovascular system, the immune system, diabetes, the central nervous system, endocrine system and the role of taurine supplements in nutrition. It also includes presentations of novel animal experimental models using Cdo1 and CSAD knock-out mice.
  • Taurine. 6 2006
  • Taurine. 7 2009
  • Taurine. 8 v. 1-2, 2013.
    v.2 Springer
    Volume 1. The Nervous system, immune system, diabetes and the cardiovascular system -- Volume 2. Nutrition and metabolism, protective role, and role in reproduction, development, and differientiation.
  • Pt. I. Principles of taxonomy. The magnitude and diversity of infectious diseases -- What is a classification? -- The tree of life -- pt. II. Bacteria. Overview of Class Bacteria -- The Alpha Proteobacteria -- Beta Proteobacteria -- Gamma Proteobacteria -- Epsilon Proteobacteria -- Spirochaetes -- Bacteroidetes and Fusobacteria -- Mollicutes -- Class Bacilli plus Class Clostridia -- Chlamydiae -- Actinobacteria -- pt. III. Eukaryotes. Overview of Class Eukaryota -- Metamonada -- Euglenozoa -- Percolozoa -- Apicomplexa -- Ciliophora (ciliates) -- Heterokontophyta -- Amoebozoa -- Choanozoa -- Archaeplastida -- pt. IV. Animals. Overview of Class Animalia -- Platyhelminthes (flatworms) -- Nematoda (roundworms) -- Acanthocephala -- Chelicerata -- Hexapoda -- Crustacea -- Craniata -- pt. V. Fungi. Overview of Class Fungi -- Zygomycota -- Basidiomycota -- Ascomycota -- Microsporidia -- pt. VI. Nonliving infectious agents : viruses and prions. Overview of viruses -- Group I viruses : double-stranded DNA -- Group II viruses : single-stranded (+)sense DNA -- Group III viruses : double-stranded RNA -- Group IV viruses : single-stranded (+)sense RNA -- Group V viruses : single stranded (-)sense RNA -- Group VI viruses : single-stranded RNA reverse transcriptase viruses with a DNA intermediate in life-cycle -- Group VII viruses : double stranded DNA reverse transcriptase viruses -- Prions -- Appendices : I. Additional notes on taxonomy -- II. Number of occurrences in some common infectious diseases -- III. Organisms causing infectious disease in humans.
  • Taxonomy of Prokaryotes presents experimental approaches in the detail required for modern microbiological research. Focusing on the methods most useful for the microbiologist interested in this specialty, this volume may be of interest to researchers working in microbiology, immunology, virology, mycology and parasitology.
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    "Taylor's Differential Diagnosis manual is a quick-reference pocket book, written for primary care professionals who face diagnostic problems in brief office visits. It offers evidence-based guidelines on which key questions to ask and what data to obtain in order to provide sound diagnoses of common adult problems. More than 140 chapters in eighteen sections cover symptoms and signs in mental health problems, vision, ear nose and throat, cardiovascular, respiratory, urologic, female reproductive, musculoskeletal, dermatology and more. New for this edition are new chapters on abnormal mammogram, anticoagulation, bipolar disorder, corneal abrasion, dyspareunia and loss of vision as well as the latest clinical evidence and changes in clinical practice since the prior edition"--Provided by publisher.
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  • Disorders of the back and neck -- Disorders of the upper extremity -- Disorders of the lower extremity -- Osteoarthritis -- Rheumatoid arthritis and related disorders -- Selected disordeers of the musculoskeletal system -- Musculoskeletal problems of children -- Osteoporosis -- Gout -- Athletic injuries -- Care of acute lacerations -- Selected injuries.
  • Section I: General topics affecting gynecologic surgery practice -- Operative gynecology before the era of laparoscopy: a brief history / Gert H. Brieger -- The ethics of pelvic surgery / Ruth M. Farrell, Eli A. Rybak, and Edward Wallach -- Psychological aspects of pelvic surgery / Betty Ruth Speir -- Professional liability and risk management for the gynecologic surgeon / Charles J. Ward -- The changing environment in which we practice gynecologic surgery / Eric J. Bieber and Edie L. Derian -- Training the gynecologic surgeon / Robert M. Rogers, Jr. -- Section II: Principles of anatomy and perioperative considerations -- Surgical anatomy of the female pelvis / John O. L. DeLancey -- Preoperative care / Sanford M. Markham and John A. Rock -- Postanesthesia and postoperative care / Alexander Duncan, Ira R. Horowitz, and Kenneth Kalassian -- Water, electrolyte, and acid-base metabolism / Jack B. Basil -- Postoperative infections: prevention and management / W. David Hager and John W. Larsen -- Shock in the gynecologic patient / Harriet O. Smith and Heather M. Greene -- Wound healing, suture material, and surgical instrumentation / Gary H. Lipscomb -- Section III: Principles of gynecologic surgical techniques and management of endoscopy -- Incisions for gynecologic surgery / James J. Burke II and Donald G. Gallup -- Principles of electrosurgery as applied to gynecology / Richard M. Soderstrom and Andrew I. Brill -- Application of laser gynecology / John L. Marlow -- Diagnostic and operative laparoscopy / Howard T. Sharp, Sean L. Francis, and Ana Alvarez Murphy -- Operative hysteroscopy / Michael S. Baggish -- Control of pelvic hemorrhage / Howard W. Jones III and William A. Rock, Jr. -- Section IV: Surgery for fertility -- The impact of assisted reproductive technology on gynecological surgery / Howard W. Jones, Jr. -- Reconstructive tubal surgery / Victor Gomel and Elizabeth Taylor -- Endometriosis / John S. Hesla and John A. Rock -- Section V: Surgery for benign gynecologic conditions -- Surgical conditions of the vulva / Ira R. Horowitz, Joseph Buscema, and Bhagirath Majmudar -- Surgical conditions of the vagina and urethra / Celia E. Dominguez, John A. Rock, and Ira R. Horowitz -- Surgery for anomalies of the müllerian ducts / John A. Rock and Lesley L. Breech -- Normal and abnormal uterine bleeding / William J. Butler and David E. Carnovale -- Tubal sterilization / Herbert B. Peterson, Amy E. Pollack, and Jeffrey S. Warshaw -- Surgery for benign disease of the ovary / Joseph S. Sanfilippo and John A. Rock -- Persistent or chronic pelvic pain / John F. Steege -- Pelvic inflammatory disease / Mark G. Martens -- Leiomyomata uteri and myomectomy / Lesley L. Breech and John A. Rock -- Abdominal hysterectomy / Howard W. Jones III -- Vaginal hysterectomy / S. Robert Kovac -- Laparoscopic hysterectomy / Fred M. Howard -- Section VI: Surgery for obstetrics -- Management of abortion / Melissa J. Kottke and Mimi Zieman -- Ectopic pregnancy / Mark A. Damario and John A. Rock -- Obstetric problems / Cornelia R. Graves -- Ovarian tumors complicating pregnancy / Cornelia R. Graves and Lynn Parker -- Section VII: Surgery for corrections of defects in pelvic support and pelvic fistulas -- Pelvic organ prolapse----basic principles / Carl W. Zimmerman -- Site-specific repair of cystourethrocele / Carl W. Zimmerman -- Paravaginal defect repair / Bobby Shull -- Posterior compartment defects / Thomas M. Julian -- Vaginal vault prolapse / Steven D. Kleeman and Mickey M. Karram -- The nonsurgical management of pelvic organ prolapse: the use of vaginal pessaries / Rony A. Adam -- Stress urinary incontinence / Alfred E. Bent -- Operative injuries to the ureter / Paul Underwood, Jr. -- Vesicovaginal fistula and urethrovaginal fistula / G. Rodney Meeks and Ted M. Roth -- Anal incontinence and rectovaginal fistulas / Michael P. Aronson and Raymond A. Lee -- Section VIII: Related surgery -- Breast diseases: benign and malignant / Victoria L. Green -- The vermiform appendix in relation to gynecology / Barry K. Jarnagin -- Intestinal tract in gynecologic surgery / Kelly L. Molpus -- Nongynecologic condition encountered by the gynecologic surgeon / James R. Dolan and Michael D. Moen -- Section IX: Gynecologic oncology -- Malignancies of the vulva / Mitchel S. Hoffman -- Cervical cancer precursors and their management / Howard W. Jones III -- Cancer of the cervix / Dennis S. Chi ... [et al.] -- Endometrial cancer / Marta Ann Crispens -- Ovarian cancer: etiology, screening, and surgery / John R. Van Nagell, Jr., and David M. Gershenson -- Pelvic exenteration / Thomas W. Burke -- Surgical reconstruction of the pelvis in gynecologic cancer patients / Luis E. Mendez and Manuel Penalver.
  • Green tea and black tea: manufacturing and consumption / Xiaochun Wan, Daxiang Li, and Zhengzhu Zhang -- Pu-erh tea: its manufacturing and health benefits / Huai-Yuan Chen, Shoei-Yn Lin-Shiau, and Jen-Kun Lin -- White tea: its manufacture, chemistry, and health effects / He-Yuan Jiang -- Biological functions and manufacturing of GABA tea / Andi Shau-mei Ou, Yung-sheng Tsai, and Hsueh-fang Wang -- Production of theaflavins, theasinensins, and related polyphenols during tea fermentation / Takashi Tanaka, Yosuke Matsuo, and Isao Kouno -- Analytical methods for bioactive compounds in teas / Chi-Chun Wong .. [et al.] -- Bioavailability and metabolism of tea catechins in human subjects / Ting Sun, Chi-Tang Ho, and Fereidoon Shahidi -- Antioxidant properties and mechanisms of tea polyphenols / Xiaochun Wan, Daxiang Li, and Zhengzhu Zhang -- Mechanisms of cancer chemoprevention by tea and tea polyphenols / Jen-Kun Lin -- Effect of tea and tea constituents on inflammation / Divya Ramji ... [et al.] -- Inhibition of breast cancer cell proliferation by theaflavins and epigallocatechin 3-gallate through suppressing proteasomal activities / Jen-Kun Lin, Yu-Wen Chen, and Shoei-Yn Lin-Shiau -- Suppression of prostate carcinogenesis by tea polyphenols through inhibiting microsomal aromatase and 5-a-reductase / Jen-Kun Lin -- Green tea-induced thermogenesis controlling body weight / John Shi, Sophia Jun Xue, and Yukio Kakuda -- Fermented tea is more effective than unfermented tea in suppressing lipogenesis and obesity / Jen-Kun Lin and Shoei-Yn Lin-Shiau -- Trapping of methylglyoxal by tea polyphenols / Di Tan ... [et al.] -- Chemistry and biological properties of theanine / Xiaochun Wan, Zhengzhu Zhang, and Daxiang Li -- Flavor stability of tea drinks / Hideki Masuda.
  • Teach yourself visually iPad 2010
    ProQuest Safari
    Exploring the iPad -- Understanding what you can do with your iPad -- Configuring the iPad -- Getting the most from the internet -- Maximizing email on the iPad -- Syncing the iPad -- Getting the most from iTunes and photos -- Getting the most from YouTube and iBooks -- Managing contacts and appointments -- Simplifying your life with the iPad -- Enhance your iPad with the app store -- Maintaining and troubleshooting the iPad.
  • Teaching Anatomy: A Practical Guide is the first book designed to provide highly practical advice to both novice and experienced gross anatomy teachers. The volume provides a theoretical foundation of adult learning and basic anatomy education and includes chapters focusing on specific issues that teachers commonly encounter in the diverse and challenging scenarios in which they teach. The book is designed to allow teachers to adopt a student-centered approach and to be able to give their students an effective and efficient overall learning experience. Teachers of gross anatomy and other basic sciences in undergraduate healthcare programs will find in this unique volume invaluable information presented in a problem-oriented, succinct, and user-friendly format. Developed by renowned, expert authors, the chapters are written concisely and in simple language, and a wealth of text boxes are provided to bring out key points, to stimulate reflection on the reader?s own situation, and to provide additional practical tips. Educational theories are selectively included to explain the theoretical foundation underlying practical suggestions, so that teachers can appropriately modify the strategies described in the book to fit their own educational environments. Comprehensive and a significant contribution to the literature, Teaching Anatomy: A Practical Guide is an indispensable resource for all instructors in gross anatomy.
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  • This book considers the evolution of medical education over the centuries, presents various theories and principles of learning, and discusses different forms of medical curriculum and the strategies employed to develop them, citing examples from medical schools in developed and developing nations. Instructional methodologies and tools for assessment and evaluation are discussed at length and additional elements of modern medical teaching, such as writing skills, communication skills, evidence based medicine, medical ethics, skill labs, and webinars, are fully considered. In discussing these topics, the authors draw upon the personal experience that they have gained in learning, teaching and disseminating knowledge in many parts of the world over the past four decades. .
  • An case-based reference covering the full spectrum of common and uncommon problems of the gastrointestinal and genitourinary tract encountered in everyday practice. The book organizes cases into sections based on the anatomic location of the problem. Each chapter provides succinct descriptions of clinical presentation, radiologic findings, diagnosis, and differential diagnosis for the case. The chapter then discusses the background for each diagnosis, clinical findings, common complications, etiology, imaging findings, treatment, and prognosis.
  • This book is a comprehensive, hands-on guide to evaluating chest images. It is ideal for reading cover-to-cover, or as a reference of radiological presentations for common thoracic disorders.The reader will learn to interpret chest images and recognize the imaging findings, generate an appropriate differential diagnosis, and understand the underlying disease process. The atlas begins with a review of normal thoracic radiography, CT, and MR anatomy, and goes on to present cases on a wide range of congenital, traumatic, and acquired thoracic conditions. Each case is supported by a discussion of etiology, pathology, imaging findings, treatment, and prognosis in a concise, bullet format to give you a complete clinical overview of each disorder. Images demonstrate normal and pathologic findings, and complementary scans demonstrate additional imaging manifestations of disease entities.
  • Kadir (radiology, St. Louis U.) presents a guide to using interventional radiology in the treatment of non-vascular diseases of the neck, thorax, abdomen, gastrointestinal system, liver, billary system, pancreas, reproduction organs, urinary system, and adrenal glands as well as abscess drainage and biopsies. In 55 chapters, the international group of practitioners describes the clinical presentation, diagnosis, and radiological studies in addition to treatment, with illustrations in each chapter. It is the second volume to Teaching Atlas of Interventional Radiology: Diagnostic and Therapeutic Angiography.
  • "The thoroughly revised and expanded 4th edition of the bestselling "Teaching Atlas of Mammography" contains a significant number of new cases. Based on 40 years of experience, the superbly illustrated cases often show long-term follow-up of patients over a period of up to 25 years. Rather than starting with the diagnosis and demonstrating typical findings, the approach of this atlas is to teach the reader and allow him to practice through 154 paradigm cases: how to systematically review mammograms for even the most subtle hints of malignancy, and how to carefully analyze and evaluate the mammographic signs to reach the correct diagnosis. Still unique to this book is the correlation of imaging findings with the corresponding large thin-section and subgross, large thick-section (3D) histology to facilitate an understanding of the pathological processes leading to the mammographic appearances. This approach is the basis for a profound understanding of breast imaging because it is a direct and effective method of teaching differential diagnosis of benign and malignant breast diseases"--Provided by publisher.
  • I. Internal Joint Derangement; II. Tumors; III. Infection; IV. Avascular bone; V. Trauma; VI. Arthritis.
  • "Complete with the insights of leading pediatric radiologists, Teaching Atlas of Pediatric Imaging provides 125 cases that address the challenging real-life clinical problems that you are likely to encounter. Each chapter presents a different case with a complete patient work-up that includes clinical presentation, diagnosis, differential diagnoses, radiological and clinical findings, treatment summary, and suggested readings. With a view to providing the opportunity for self-assessment, the authors omit the diagnosis from the first pages of each case to enable self-testing and review."--Publisher's website.
  • This book presents a case-based approach to selecting the multimodality imaging strategies for the most frequently encountered urologic disorders. The book provides comprehensive coverage of the latest imaging techniques with an emphasis on newer modalities such as CT intravenous pyelograms (CT-IVP) and MRI for the genitourinary system. Each case opens with a concise description of the clinical presentation, radiologic findings, diagnosis, and differential diagnosis. It then concludes with a detailed discussion of the background, clinical findings, pathology, imaging findings, treatment, and prognosis for that case, and pertinent references. Features: Nearly 400 high-quality illustrations, including 47 in full color, demonstrate anatomy and pathology Consistent format of each chapter enhances ease of use Bulleted lists of differential diagnoses, this book provides a quick reference for common imaging findings and the most appropriate imaging strategies for specific diseases.
  • Provides 75 cases that cover the full range of vascular and nonvascular interventional procedures frequently performed in clinical practice. Brief sections summarizing the clinical presentation, radiologic studies, diagnosis, and treatment guide the reader through each stage of management. For each case the authors provide the essential background on the etiology of the problem and offer bulleted lists that describe the noninvasive imaging workup, therapeutic options available, and possible complications.
  • "Practical and clinically focused, Brain and Spine Imaging - a title in the Teaching Files Series - provides you with over 300 interesting and well-presented cases to help you better diagnose any disease of the brain and spine. Expert in the field, Dr. Girish Fatterpekar, MD uses a logical organization throughout, making referencing difficult diagnoses easier than ever before. Detailed discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. This unique, case-based resource offers you an ideal way to sharpen your diagnostic skills and study for board exams. And, with Expert Consult functionality, you'll have convenient access to the full text online, all of the book's illustrations, additional cases and images, and links to PubMed at"--Publisher's website.
  • Teaching files. Chest 2010
    "Practical and clinically focused, this Chest title in the new Teaching Files Series provides you with 200 interesting and well-presented cases and nearly 600 high-quality images to help you better diagnose any disease of the chest. Experts in the field, Drs. Muller and Silva, use a logical organization throughout, making referencing difficult diagnoses easier than ever before. Detailed discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. This unique, case-based resource offers you an ideal way to sharpen your diagnostic skills and study for exams. And, with Expert Consult functionality, you'll have convenient access to the full text online, all of the book's illustrations, additional cases and images, and links to Medline at"--BOOK JACKET.
  • "Drs. Sarah Milla and Sarah Bixby's The Teaching Files: Pediatrics provides you with interesting and well-presented clinical findings and images so you can better diagnose any pediatric disease. An easy-to-use, templated organization makes referencing difficult diagnoses easier than ever before. Discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. Plus, with Expert Consult functionality, you can access the full text and illustrations online from any Internet-accessible computer."--Publisher's website.
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    Shakespeare is not a one-shot deal : an open wiki model for the humanities / John Venecek and Katheryn Giglio -- Reusable learning objects : developing online information literacy instruction through collaborative design / Matthew Sylvain, Kari Mofford, Elizabeth Lehr, and Jeannette E. Riley -- Framing multiliteracies : a blended and holistic approach to digital technology education / Andrew Whitworth, Ian Fishwick, and Steve McIndoe -- Finding your fate : the evolution of a librarian faculty collaboration to bring history online / Kristina DuRocher and Lisa Nichols -- Supported open learning : developing an integrated information literacy strategy online / Clarissa Gosling and Ingrid Nix -- Information-literate avatars : resource-based learning in Second Life / Jenna Kammer and Tracey Thompson -- Information literacy by design recalibrating graduate professional asynchronous online programs / David Lavoie, Andrew Rosman, and Shikha Sharma -- Working outside the org chart a faculty librarian partnership to design an online graduate course / Susan M. Frey and Rebecca L Fiedler.
  • Part I: Clinical and Cultural Context -- Chapter 1. Getting grounded (in our own instability) -- Chapter 2. A history exercise to locate "mindfulness" now -- Chapter 3. Building a "working" definition of mindfulness -- Part II: Authenticity, Authority, and Friendship -- Chapter 4. The Person of the Teacher -- Chapter 5. The skills of the teacher -- Part III: Towards an "Empty" Curriculum -- Chapter 6. Organizing the intentions of teaching -- Chapter 7. Fulfilling the intentions of teaching -- Chapter 8. Practices and resources.
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    v. 1. Schizophrenia, paranoid conditions [and] depressions / by P.G.S. Beckett and T.H. Bleakley -- v. 2. Psychoneurosis, organic brain disease, psychopharmacology / by P.G.S. Beckett, E.F. Domino, and T.H. Bleakley.
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    1. Web searching and the teaching paradox -- Online searching background -- Internet information growth -- Origins of the Web -- Instructional background -- The teaching connection -- Teaching simplicity -- The state of Web searching today -- Changing patterns -- 2. Understanding our audience -- General audience characteristics -- Novices -- Know-it-alls -- Experienced users -- Pairing strategies for hands-on workshops -- Audience assessment -- Navigation versus search confusion -- Remembering what we did not know -- Box confusion -- Address confusion -- Button confusion -- Browser differences and problems -- Operating system and hardware issues -- Adaptability and change -- 3. Choosing an instructional session type -- Hands-on sessions -- Advantages -- Disadvantages -- Facilities -- Planning -- Exercises -- Lecture and demonstration sessions -- Advantages -- Disadvantages -- Facilities -- Planning -- Semi-online tutorials -- Capturing a screen shot within PowerPoint -- Course coverage and distance education -- Other settings and approaches -- 4. Online tutorials : friend or foe? -- Advantages -- Disadvantages -- Issues with online tutorials for Web searching -- Search engine inconsistencies -- Search feature changes -- Databases changes -- Online tutorial examples -- Web search guide tutorial : research, Web searching -- Finding information on the Internet : a tutorial -- Internet tutorials -- LearnAndGo, searching the Web -- Quick tutorial on searching the Internet -- Net.TUTOR : using Web search tools -- Interactive tutorials : Internet search tips and mouse exercise -- Tutorial : site clustering and filtering -- The information cycle -- Information literacy online tutorials -- Finding tutorials -- Tutorials : worth the effort? -- 5. Organization : focus, length, and goals -- Primary session focus -- Pure Web searching -- Basic Internet training -- Advanced Internet training -- Part of multiple sessions -- Course-integrated bibliographic instruction -- Session length -- Variations in length -- Ideal length -- The burnout paradox -- Goal setting -- A collection of goals -- How many main goals? -- Specific objectives -- Bringing it all together -- 6. Terminology -- Importance of terminology -- Definitions -- Search engine -- Directory -- Portal -- Metasearch engine -- Ad bidding engine -- Answer engine -- Metasite -- News search engine -- Opinion engine -- Site search engine -- Invisible Web -- Other terminology distinctions -- Final thoughts on terminology -- 7. Content : Web search features -- Search features -- Phrase searching -- Boolean searching -- Truncation -- Field searching -- Limits -- Stop words and case sensitivity -- Sorting -- The teaching choice -- 8. Content : primary concepts -- Research process -- Question analysis -- Using more than one search tool -- Search engines versus directories -- Evaluation -- Which primary concepts to teach -- Recent changes in teaching topics -- Additional concepts to consider -- Identifying ads -- Understanding Web addresses (or URLs) -- Understanding databases -- Teaching change -- 9. Additional content : image searching, news, Usenet, and more -- News -- Usenet newsgroups and opinions -- Pictures and images -- Multimedia -- Phone numbers -- Bibliographic databases -- Subject-specific sites -- Invisible Web -- The lost obvious -- 10. The search engines -- The starting point -- Ask -- Exalead -- Gigablast -- Google -- MSN search -- Windows Live -- Yahoo! -- Directories -- 11. Creating a framed workshop Web page -- Advantages and disadvantages of frames -- Frames code and explanation -- Top page with frameset -- Left frame table of contents -- Content pages -- Exercise pages frame set -- Exercise one top frame : JavaScript and a form -- Other exercise pages -- Solutions for frame breakers -- 12. Presentation tips, tricks, and shortcuts -- Keyboard shortcuts -- General Windows shortcuts -- Browser shortcut keys -- Shortcuts for filling out forms -- Other shortcuts -- Quick links and the personal toolbar -- Bookmarklets -- Zapping images, animations, and more -- Bookmarklets for Web searching -- The pop-up presence -- The shortcut advantage -- 13. Tales from the trenches : anecdotes, examples, and exercises -- Analogies, sayings, and terminology tales -- Boolean examples -- Exercises -- Unexpected answers -- Limitations of search engines -- Failures -- Facilities failures -- The team teaching danger -- Web site instruction and the Web searching paradox -- Lost interest -- Formulas for success -- Afterword -- Appendix A. The trainers : introduction to the interviewees -- Appendix B. Sample handouts and other training material -- Appendix C. URL list.
  • Part I. Understanding Tech Mining -- Chapter 1. Technological Innovation and the Need for Tech Mining , p. 2-15 -- Chapter 2. How Tech Mining Works, p. 17-32 -- Chapter 3. What Tech Mining Can Do for You, p. 33-40 -- Chapter 4. Example Results. Fuel Cells Tech Mining, p. 41-50 -- Chapter 5. What to Watch for in Tech Mining, p. 51-66 -- Part II. Doing Tech Mining -- Chapter 7. Forming the Right Query, p. 95-111 -- Chapter 8. Getting the Data, p. 113-127 -- Chapter 9. Basic Analyses, p. 129-154 -- Chapter 10. Advanced Analyses, p. 155-186 -- Chapter 11. Trend Analyses, p. 187-214 -- Chapter 12. Patent Analyses, p. 215-248 -- Chapter 13. Generating and Presenting Innovation Indicators, p. 249-288 -- Chapter 14. Managing the Tech Mining Process, p. 289-306 -- Chapter 15. Measuring Tech Mining Results, p. 307-320 -- Chapter 16. Example Process. Tech Mining on Fuel Cells, p. 321-354 -- Appendix A. Selected Publication and Patent Databases, p. 355-359 -- Appendix B. Text Mining Software, p. 361-362 -- Appendix C. What You Can Do without Tech Mining Software, p. 363-364 -- Appendix D. Statistics and Distributions for Analyzing Text Entities, p. 365-368.
  • Focal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy. These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity. As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure. Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists.
  • This well-received book, now in its fifth edition, is unique in providing a detailed description of the technological basis of radiation therapy. Another novel feature is the collaborative writing of the chapters by North American and European authors. This considerably broadens the book{u2019}s perspective and increases its applicability in daily practice throughout the world. The book is divided into two sections. The first covers basic concepts in treatment planning, including essential physics and biological principles related to time-dose-fractionation, and explains the various technological approaches to radiation therapy, such as intensity-modulated radiation therapy, tomotherapy, stereotactic radiotherapy, and high and low dose rate brachytherapy. Issues relating to quality assurance, technology assessment, and cost-benefit analysis are also reviewed. The second part of the book discusses in depth the practical clinical applications of the different radiation therapy techniques in a wide range of cancer sites. All of the chapters have been written by leaders in the field. This book will serve to instruct and acquaint teachers, students, and practitioners in the various fields of oncology with the basic technological factors and approaches in radiation therapy.
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    v. 1. Physical methods of organic chemistry.
  • "Cartilage defects are common. Cartilage repair surgery is not only fascinating but also surgically challenging. There are books dealing with basic science and some surgical aspect. This book fills a gap in surgical techniques for cartilage repair. All of the surgical chapters are logically organised, covering patient selection, patient setup/positioning, surgical approach, potential complications and troubleshooting. An attempt is made to compare with various surgical techniques. This book also covers anaesthesia, postoperative follow-up, pain management and rehabilitation. Both the editors and the authors are renowned experts in the field. This book will be invaluable for orthopaedic and sports medicine surgeons (consultants and training doctors) and is also of potential interest to physiotherapists, medical students, general practitioners, physical medicine and rehabilitation specialists, and rheumatology specialists."--Publisher's website.
  • v. 9-, 2007- ClinicalKey
  • Drs. Jon K. Sekiya, Marc Safran, Anil S. Ranawat, and Michael Leunig provide a step-by-step, balanced approach-with contributions from an array of North American and international surgeons-to pre-operative planning, surgical technique, technical pearls, management of complications, and post-operative rehabilitation. Surgical videos on DVD demonstrate techniques such as surgical hip dislocation for femoracetabular impingement and arthroscopic femoral osteoplasty so you can provide your patients with the best possible outcomes. Grasp the visual nuances of each technique through full-color surgical illustrations and intraoperative photographs. Watch expert surgeons perform cutting edge procedures-such as complex therapeutic hip arthroscopy using a femoral distractor, arhroscopic synovectomy and treatment of synovial disorders, surgical hip dislocation for femoracetabular important, and arthroscopic femoral osteoplasty-on DVD. Find information quickly and easily thanks to the consistent chapter format that includes technical pearls.
  • Techniques in Revision Hip and Knee Arthroplasty is the one authoritative volume that gives you an efficient, problem-based approach to revision arthroplasty of both the hip and knee. Dr. Giles Scuderi and other leading experts from North America and Western Europe present their favored surgical procedures and post-surgical management strategies in this straightforward, heavily illustrated, video-intensive reference. It's your one-stop, go-to guide for successful revision surgery for a myriad of complications, such as implant loosening, polyethylene wear, osteolysis, or infection of the hip and knee. Get expert guidance on implant choice, management of complications (including infection and wound healing), and failure of mechanisms, as well as step-by-step surgical techniques.Quickly find the exact information you need with a straightforward "just what you need to know" approach, including surgical tips and pearls.Stay up to date with new insights regarding anatomic landmarks, recommended reconstruction options in revision surgery, including management of bone defects and instability.Access the fully searchable contents of the book and an abundance of surgical videos online at Expert Consult.
  • Wrist arthroscopy portals / David J. Slutsky -- Trapeziometacarpal and scaphotrapezial arthroscopy portals / David J. Slutsky -- The ulnocarpal joint. Arthroscopically assisted ulnar shortening / Daniel J. Nagle -- Arthroscopic treatment of radial-sided TFCC lesions / Jennifer Weintraub, A. Lee Osterman, and Jeffrey Yao -- Peripheral tears of the TFCC: arthroscopic diagnosis and management / Thomas E. Trumble and Seth D. Dodds -- Arthroscopy of the distal radioulnar joint / Ericka A. Lawler and Brian D. Adams -- Class IIA and B ulnar impaction: treatment with arthroscopic TFCC disc excision and wafer distal ulna resection / Matthew M. Tomaino -- Carpal ligament injury. Arthroscopic treatment of scapholunate ligament tears / Steven H. Goldberg ... [et al.] -- Arthroscopic RASL / Michael R. Hausman -- Arthroscopic thermal shrinkage for scapholunate ligament injuries / Ferdinando Battistella, Pau Golano, and Ettore Taverna -- Arthroscopic treatment of lunotriquetral ligament injuries / Gregory J. Hanker -- Arthroscopic plication of lunotriquetral ligament tears / Jason W. Levine, Felix H. Savoie III, and Michael J. Moskal -- Arthroscopic dorsal readiocarpal ligament repair / David J. Slutsky -- The role of arthroscopy in midcarpal instability / David M. Lichtman ... [et al.] -- Capsular shrinkage in the treatment of wrist instability / David J. Nagle -- Writst and carpal fractures. Arthroscopically assisted reduction and percutaneous fixation of scaphoid fractures using a simple external targeting system / Joseph F. Slade III and Greg Merrell -- The role of wrist arthroscopy in intra-articular distal radius fracture management / William B. Geissler -- Correction of mal-united intra-articular distal radius fractures with and inside-out osteotomy technique / Franscisco del Piñal -- Arthroscopic wrist capsulotomy / David J. Slutsky -- Arthroscopic synovectomy and abrasion chondroplasty of the wrist / Kevin D. Plancher and Césaw J. Bruno -- Arthroscopic wrist ganglionectomy / Randy R. Bindra -- Arthroscopic treatment of volar carpal ganglion cysts / Jeffrey A. Greenberg -- Arhtoscopically assisted treatment of intraosseous gaglions of the lunate / N. Ashwood and G.I. Bain -- Arthroscopic radial styloidectomy / David J. Slutsky -- Arthroscopic resection of arthosis of the proximal hamate / Brian J. Harley and Andrew K. Palmer -- Arthroscopic proximal row carpectomy / Randall W. Culp and Eric S. Wroten -- Anthroscopy of the small joints of the hand / Richard A. Berger -- Small-joint arthroscopy. Arthroscopic treatment of trapeziometacarpal diseaes / David J. Slutsky -- Arthroscopic debridement for isolated scaphotrapeziotrapezoid arthritis / N. Ashwood and G.I. Bain -- Extra-articular procedures. Agee endoscopic carpal tunnel release / David J. Slutsky -- Endoscopic carpal tunnel release: the chow dual-portal technique / Daniel J. Nagle -- Endoscopic release of the first dorsal extensor tendon compartment / Joseph F. Slade III and Greg Merrell.
  • Glycemic control -- Home blood glucose monitoring -- Continuous glucose monitoring -- Insulin delivery system -- Closed-loop insulin-delivery system -- Alternatives to insulin injection -- Devices to support treatmtne decisions -- Electronic medical record.
  • Rapid progress in health research has led to generation of new knowledge and innovative practices in management of illness. This has resulted in a significant challenge for health professionals: if today we discovered a new therapy through research, when will this discovery be regularly prescribed or utilized to treat all patients suffering from this condition? Knowledge translation is the non-linear and often complicated process of translating knowledge into routine health practices. Technology enabled knowledge translation (TEKT) is the use of information and communication technologies (ICT) to accelerate knowledge translation. With the ubiquity of the internet, the proliferation of different approaches in communication and social networking, and the continuously improving technologies from netbooks to smartphones, there are rich opportunities for TEKT in health education, service delivery, and research.
  • Applied groundwork for a practical moral code. Introduction ; Definitions ; Professional moral codes ; USDA study : methodology and results ; Formalization and evaluation of the USDA study's moral codes ; Formalization of the combination moral code ; Problems for the combination moral code ; Conclusion -- A practical moral code. Introduction ; Utilitarianism ; What is a reasonable person? ; RPU's benefits ; Respecting persons ; Working toward a plausible distributive/social justice principle ; The moral paradigm test ; Conclusion -- Are transgenic organisms, biotechnology, and technology unnatural? Introduction ; The unnatural is unethical argument ; The weak definitions ; A "playing God" argument ; More complex meanings of the unnatural ; Arguments from evolution ; Conclusion -- A natural theory of value. Introduction ; Naturalness as sacredness ; Beginning an axiology ; The benefit of the doubt principle ; Intrinsically valuable things and their rankings ; Is nature or the biosphere alive? ; Arguments against nature's intrinsic value ; Conclusion -- Applying PMC to a few transgenic technology issues. Introduction ; The practical moral code again ; Transgenics and RPU ; Transgenics and QCI ; Legal/moral questions ; Conclusion.
  • Wake Forest University -- Basic Physics of Ultrasound -- Systolic LV Structure/Function -- Diastolic Function -- Aortic Valve Anatomy -- Aortic Valve Stenosis -- Aortic Regurgitation -- Mitral Valve Anatomy -- Mitral Valve Stenosis -- Mitral Valve Regurgitation -- Pulmonic Valve -- Tricuspid Valve -- Right Ventricle -- Prosthetic Valve Types -- Eendocarditis -- Pericardial Disease -- Aoritc Atherosclerosis Aneurysm Dissection -- Adult Congenital Heart Disease -- Intracardiac Masses and Objects -- Artifacts and Pitfalls -- Equations and Calculations -- Intraoperative Aoperative ₃-Dimensional (₃D) Tee.
  • On the relationship between calculus and caries / Duckworth, R.M., Huntington, E. -- The structure, function and properties of the acquired pellicle / Hannig, M., Joiner, A. -- Model parameters and their influence on the outcome of in vitro demineralisation and remineralisation studies / Lynch, R.J.M. -- Tooth wear / Pickles, M.J. -- Nanomechanics, chemistry and structure at the enamel surface / Mann, A.B., Dickinson, M.E. -- Plaque as a reservoir for active ingredients / Duckworth, R.M., Gao, X.J.
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  • Tele-oncology 2015
    1 Introduction -- 2 Overview and Background -- PART I -- Fields of application 3 The community: Early diagnosis and prevention -- 4 The hospital: Improving hospital care for people with cancer -- 5 Home-based care for a better quality of life: Treatment, monitoring and follow-up -- PART II -- Technical Issues 6 New technologies and new frontiers -- 7 The social web -- PART III -- Complex Scenarios and Special Settings -- 8 Rural and extreme rural settings -- 9 Tele-oncology in developing countries -- PART IV -- eLearning 10 Education and distant learning -- 11 Health education to improve prevention -- 12 Conclusions.
  • Pt. 1. System : tele-healthcare monitoring networks -- pt. 2. Hardware : medical sensors and devices -- pt. 3. Software : medical signal processing -- pt. 4. Others : medical security and privacy.
  • "This book describes in detail the potential role of ICT and electronic systems, together with the application of Web 2.0 technologies, in telepediatrics and child health. Rather than simply proposing engineering solutions that may soon become outdated, it is designed to address those real needs that telemedicine and developers are asked to meet. The orientation of the book is very much toward primary care, and both low- and high-income settings as well as extreme or complex scenarios are considered. The first two sections of the book describe different fields of application, such as the community, the hospital, and children with chronic illnesses or special needs, and examine technical issues. The use of telemedicine in delivery of care in extreme rural settings and developing countries is then discussed, with attention also to major emergencies and humanitarian crises. The closing chapters consider the role of modern technologies in the education of caregivers who work with children. Child health is a crucial issue in both industrialized and developing countries. Telemedicine for Children's Health will be an excellent guide to the potential value of telemedicine devices in reducing the burden for children and parents and in offering quick and concrete solutions in low-resource scenarios"--Provided by publisher.
  • Introduction to Teledermatology -- Historical Review -- Medical Prerequisites -- Technical Prerequisites -- Photographic Imaging Essentials -- Performance of Teledermatology including Clinical Examples -- Teledermatology in Underdeveloping Countries -- Special Methods of Teledermatology -- Teledermatology and Reflectance Confocal Microscopy Quality Assurance -- Legal Assumptions -- Economic Aspects and Cost-effectiveness -- Future Horizons -- APPENDIX: Education and Training Opportunities -- Quality Certificate Teledermatology -- Sample Protocol, Consent Form and Information Sheet -- References and Relevant Web links -- Glossary -- Subject Index.
  • Part 1. GENERAL -- History of Microsurgery / Yoshikazu Ikuta -- History of Telesurgery / James Wall and Jacques Marescaux -- Description of Robots / Jesse Creed Selber -- Instruments / Sijo Joseph Parekatti and Michael Moran -- Robot Installation in Telemicrosurgery / Thierry Lequint, Kiyohito Naito, Eric Nectoux, Sybille Facca and Philippe Liverneaux -- Part 2. TRAINING -- Earthworms / Gustavo Mantovani Ruggiero -- Vessels / Joo-Yup Lee and Alexander Y. Shin -- Nerves / Stacey H. Berner -- Part 3. EXPERIMENTAL RESEARCH -- Free Tissue Transfer / Stacey H. Berner -- Tele-endomicrosurgery / Sybille Facca, Kiyohito Naito, Thierry Lequint, Eric Nectoux and Philippe Liverneaux -- Brachial Plexus Repair / Gustavo Mantovani Ruggiero and Philippe Liverneaux -- Tendon Transfer / Michael S. Bednar -- Part 4. CLINICAL APPLICATIONS -- Nerve Entrapment / Jose Carlos Garcia Jr. -- Nerve Repair / Stacey H. Berner -- Brachial Plexus / Kiyohito Naito, Mickaël Ohana, Thierry Lequint, Sybille Facca and Philippe Liverneaux -- Skin Flaps / Thomas Lauwers, Tom Van Mulken and Darren Booi -- Muscle Flaps / Jesse Creed Selber and John C. Pedersen -- Head and Neck / Jesse Creed Selber -- Urology / Sijo Joseph Parekattil -- Part 5. PERSPECTIVES -- Supermicrosurgery / Takeshi Todokoro and Isao Koshima -- Network / Catherine Jane Mohr.
  • "Medical information is now widely available on the Internet and through telephone helplines such as NHS Direct and the focus on patient self care is likely to increase. Clinicians in all specialties will often encounter patients who have made self-directed searches for medical information prior to the clinical encounter. 'Teleneurology by Internet and Telephone' is a study of patient information-seeking behaviour in neurology patients prior to referral from primary to secondary care. The book analyses frequency of Internet access and use, and of telephone helpline awareness and use. It also explores use of these modalities over time, use according to patient gender and age and by gender and age over time. 'Teleneurology by Internet and Telephone' is an accessible overview of the utility of these modalities of health information provision and will be of interest not only to neurologists and clinicians in other specialities but also to public health researchers, sociologists and political scientists with an interest in questions of health care provision"--Provided by publisher.
  • Teleneurology in the United States Veteran Health Administration -- International Teleneurology -- Military Telemedicine -- Telemedicine Technology -- Telestroke -- Teleneurointensive Care Unit (TeleneurolICU) -- Teleneurology and Neurointerventional Therapy for Acute Stroke -- Teleneurosurgery -- Hospital Teleneurology -- Telemedicine and Parkinson Disease -- Telebeuropatholgy -- Tele-Epilepsy and Tele-Electroencephalography -- The Emerging Relevance of Telemedicine in Sleep Medicine -- Teledementia -- The Emerging Role of Telemedicine in the Evaluation of Sports-related Concussion -- Teleneurology in Contemporary Graduate Medical Education -- Legal Considerations in the Use of Telemedicine in Neurology -- Reimbursement in Teleneurology.
  • Telenursing 2011
  • Teleophthalmology 2006
  • Applications of Teleophthalmology: Systemic Diseases (Applications) -- Ocular Diseases. Methods used in Teleophthalmology: Novel Imaging Devices -- Information Technologies.
  • Telepathology 2009
  • Teleradiology 2008
  • Telerehabilitation 2013
    Telerehabilitation, as a subset of telehealth, is the use of telecommunications to deliver rehabilitation services at a distance and can bridge the gaps created by personnel shortages that exist in underserved and remote areas, as well as serve persons in urban settings who cannot easily leave their homes or offices to seek care. Given the mobile nature of our society, telerehabilitation can enable continuity of care while persons travel for work, vacation and/or education. While the technical capacities to conduct telerehabilitation have surged ahead in the past 10 years, there has been slower, yet ongoing progress in the development of the policies (e.g., legislation; state licensure; reimbursement) that will be required to actualize widespread telepractice service delivery. Telerehabilitation presents a wide-angle view of telerehabilitation worldwide at a seminal time in its development. The book contains contributions from authors across multiple disciplines, as well as a consumer-based perspective. This book contributes significantly to the current understanding of telerehabilitation, as well as elucidating the immense potential for telerehabilitation-based service delivery to benefit persons with disabilities.
  • Telesurgery 2008
  • Methods of telomerase inhibition -- Telomerase inhibition by synthetic nucleic acids and chemosensitization in human bladder cancer cell lines -- hTERT knockdown in human embryonic kidney cells using double-stranded RNA -- RNA interference using a plasmid construct expressing a short-hairpin RNA -- Retrovirus-mediated RNA interference -- Telomerase inhibition and telomere targeting in hematopoietic cancer cell lines with small non-nucleosidic synthetic compounds (BIBR1532) -- Uses of telomerase peptides in anti-tumor immune therapy -- Establishing cell-based reporter systems for the analysis of hTERT expression -- Telomerase RNA inhibition using antisense oligonucleotide against human telomerase RNA linked to a 2',5'-oligoadenylate -- Knockdown of telomerase RNA using hammerhead ribozymes and RNA interference -- Evaluation of tankyrase inhibition in whole cells -- Inhibition of telomerase by targeting MAP kinase signaling -- Screening of telomerase inhibitors -- Telomerase inhibition combined with other chemotherapeutic reagents to enhance anti-cancer effect.
  • Introduction to telomeres and telomerase / Z. Songyang -- Analysis of average telomere length in cultured human cells / D. Liu -- Telomere length analysis by quantitative fluorescent in situ hybridization (Q-FISH) / I. Ourliac-Garnier and A. Londono-Vallejo -- Telomere strand-specific length analysis by fluorescent in situ hybridization (Q-CO-FISH) / I. Ourliac-Garnier and A. Londono-Vallejo -- Telomere G-overhang length measurement method 1: The DSN method / Y. Zhao, J.W. Shay and W.E. Wright -- Telomere G-overhang length measurement method 2: G-tail telomere HPA / H. Tahara -- Telomere terminal G/C strand synthesis: Measuring telomerase action and C-RICH fill-in / Y. Zhao, J.W. Shay and W.E. Wright -- G-quadruplex structures and G-quadruplex-interactive compounds / R.I. Mathad and D. Yang -- Analysis of yeast telomerase by primer extension assays / M. Hsu and N.F. Lue -- Telomeric repeat amplification protocol: Measuring the activity of the telomerase / H. Xin -- CO-FISH, COD-FISH, ReD-FISH, SKY-FISH / E.S. Williams [and others] -- Visualization of human telomerase localization by fluorescence microscopy techniques / E. Abreu, R.M. Terns and M.P. Terns -- Cytogenetic analysis of telomere dysfunction / A.S. Multani and S. Chang -- Probing the telomere damage response / R. Rai and S. Chang -- Analysis of telomere proteins by chromatin immunoprecipitation (CHIP) / W. Ma -- Studying of telomeric protein-protein interactions by bi-molecular fluorescence complementation (BIFC) and peptide array-based assays / W. Ma, H. Kim and Z. Songyang -- Human telomere POT1-TPP1 complex and its role in telomerase activity regulation / F. Wang and M. Lei.
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    A history of telomere biology -- The telomerase ribonucleoprotein particle -- Telomerase biochemistry and biogenesis -- Telomerase and human cancer -- Modeling cancer and aging in the telomerase-deficient mouse -- Telomerase deficiency and human disease -- Telomerase-independent maintenance of mammalian telomeres -- Telomerase-independent telomere maintenance in yeast -- Meiotic telomeres -- Telomere position effect : silencing near the end -- The structural biology of telomeres -- Budding yeast telomeres -- Mammalian telomeres -- Drosophila telomeres -- Ciliate telomeres -- Fission yeast telomeres -- Plant telomeres.
  • Imaging Technique -- Anatomy -- Multiplanar Atlas -- Advanced Imaging Applications -- Imaging Microscopy of the Temporal Bone: An Anatomy Tutorial.
  • This book, featuring more than 180 high spatial resolution images obtained with state-of-the-art MDCT and MRI scanners, depicts in superb detail the anatomy of the temporal bone, recognized to be one of the most complex anatomic areas. In order to facilitate identification of individual anatomic structures, the images are presented in the same way in which they emanate from contemporary imaging modalities, namely as consecutive submillimeter sections in standardized slice orientations, with all anatomic landmarks labeled. While various previous publications have addressed the topic of temporal bone anatomy, none has presented complete isotropic submillimeter 3D volume datasets of MDCT or MRI examinations. The Temporal Bone MDCT and MRI Anatomy offers radiologists, head and neck surgeons, neurosurgeons, and anatomists a comprehensive guide to temporal bone sectional anatomy that resembles as closely as possible the way in which it is now routinely reviewed, i.e., on the screens of diagnostic workstations or picture archiving and communication systems (PACS).
  • Temporal bone imaging 2008
    Thieme Book
    This new text covers the most important concepts of temporal bone imaging. Each chapter is organized by disease entity, including congenital malformations, neoplasms, infections/inflammatory, post-operative and more. With a wealth of information provided in an easy-to-read format, this text is ideal for neuroradiologists, radiologists and other specialists.
  • This book provides a complete overview of imaging of normal and diseased temporal bone. After description of indications for imaging and the cross-sectional imaging anatomy of the area, subsequent chapters address the various diseases and conditions that affect the temporal bone and are likely to be encountered regularly in clinical practice. The classic imaging methods are described and discussed in detail, and individual chapters are included on newer techniques such as functional imaging and diffusion-weighted imaging. There is also a strong focus on postoperative imaging. Throughout, imaging findings are documented with the aid of numerous informative, high-quality illustrations. Temporal Bone Imaging, with its straightforward structure based essentially on topography, will prove of immense value in daily practice.
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    Structure of the oral tissues -- General embryology -- Embryology of the head, face, and oral cavity -- Cytoskeleton, cell junctions, fibroblasts, and extracellular matrix -- Development of the tooth and its supporting tissues -- Bone -- Enamel : composition, formation, and structure -- Dentin-pulp complex -- Periodontium -- Physiologic tooth movement : eruption and shedding -- Salivary glands -- Oral mucosa -- Temporomandibular joint -- Facial growth and development -- Repair and regeneration of oral tissues.
  • Sect. I: Pulmonary arteries, aorta, peripheral vessels -- Sect. II: Coronary arteries -- Sect. III: Intracardiac masses -- Sect. IV: Endocardium and valves -- Sect. V: Pericardium and myocardium -- Sect. VI: Congenital heart disease.
  • Introduction: The GW Body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology -- The Discovery of GW Bodies -- The Discovery and Analysis of P Bodies -- Autoantibodies to Argonaute 2 (Su Antigen) -- GW/P-Bodies and Autoimmune Disease -- Function of GW182 and GW Bodies in siRNA and miRNA Pathways -- Post-transcriptional Stimulation of Gene Expression by MicroRNAs -- Gawky (GW) is the Drosophila melanogaster GW182 Homologue -- The Role of GW182 Proteins in miRNA-Mediated Gene Silencing -- Quantifying Argonaute Proteins In and Out of GW/P-Bodies: Implications in microRNA Activities -- Deadenylation and P-Bodies -- Relationship of GW/P-Bodies with Stress Granules -- Relationship of Other Cytoplasmic Ribonucleoprotein Bodies (cRNPB) to GW/P Bodies -- An SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182 -- Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research.
  • Part I. Basic Sciences, Etiology, Pathomechanics, and Imaging --1. Anatomy of Tendons / Moira O'Brien, p. 3-13 -- 2. Mechanical Properties of Tendons / Constantinos Maganaris and Marco Narici, p. 14-21 -- 3. Growth and Development of Tendons / Laurence Dahners, p. 22-24 -- 4. Aging and Degeneration of Tendons / Pekka Kannus, Mika Paavola and Lászlo Józsa, p. 25-31 -- 5. Epidemiology of Tendon Problems in Sport / Mika Paavola, Pekka Kannus and Markku Järvinen, p. 32-39 -- 6. Neurogenic, Mast Cell, and Gender Variables in Tendon Biology: Potential Role in Chronic Tendinopathy / David Hart, Cyril Frank, Alison Kydd, Tyler Ivie, Paul Sciore and Carol Reno, p. 40-48 -- 7. Imaging of Tendon Ailments / Tudor Hughes, p. 49-60 -- Part II. Anatomical Sites and Presentation -- 8. Injury of the Musculotendinous Junction / Jude Sullivan and Thomas Best, p. 63-69 -- 9. Insertional Tendinopathy in Sports / Per Renström and Thomas Hach, p. 70-85 -- 10. Tendon Avulsions in Children and Adolescents / Sakari Orava and Urho Kujala, p. 86-89.
  • "Get the best results from the latest procedures with Tendon Surgery of the Hand , the only reference that offers comprehensive coverage of this complex and challenging area. World-renowned experts guide you through all of the newest techniques and technologies , equipping you to restore optimal function in your patients. It's your one-stop source for mastering today's best approaches to treating tendon injuries and disorders of the hand."--Publisher's website.
  • Section I: Etiology -- Definition, Causes and Epidemiology -- Tennis Elbow in Athletes: More Than Just Tennis? -- Golfer's Elbow: Treatment Distinctions -- Section II: Conservative Treatment -- Evidence for No Treatment and Self-limited Treatment -- Medical Management: The Role of NSAIDS and Topical -- Therapy -- Splints -- Steroid Injections -- Blood and PRP Injections -- Other Treatments: Prolotherapy, Acupuncture, ESWL -- Section III: Surgery -- Open Surgical Treatment -- Arthroscopic Treatment -- Denervation -- Percutaneous Release -- Outcomes of Treatment and Return to Play: The Evidence -- Complications of Surgical Treatment and Salvage Procedures for Failed Surgery.
  • Introduction / Peter L. Elkin and Mark Samuel Tuttle -- History of Terminology and Terminological Logics / Peter L. Elkin and Mark Samuel Tuttle -- Knowledge Representation and the Logical Basis of Ontology / Peter L. Elkin and Steven H. Brown -- Theoretical Foundations of Terminology / Peter L. Elkin -- Compositionality: An Implementation Guide / Peter L. Elkin and Steven H. Brown -- Interface Terminologies / S. Trent Rosenbloom -- Springer Terminology Related Standards Development / Peter L. Elkin -- Implementations of Terminology / Peter L. Elkin, Mark Samuel Tuttle, Marjorie Rallins, Jennifer Trajkovski and Elizabeth Lumakovska, et al. -- Terminological Systems / Peter L. Elkin and Mark Samuel Tuttle -- Conclusion / Peter L. Elkin and Mark Samuel Tuttle.
  • Toward a comprehensive strategy for terrorism and homeland security / Paul R. Viotti -- The search for national and homeland security : an integrated grand strategy / Robert H. Dorff -- Assured vulnerability : homeland security and the cold war legacy of defenselessness / David Goldfischer -- Terrorism and deterrence by denial / James M. Smith and Brent J. Talbot -- The importance of multinational and transnational cooperation strategies for homeland security / Veronica M. Kitchen and Gregory J. Moore -- WMD terrorism : new threats, revised responses / Jeffrey A. Larsen and James J. Wirtz -- Nuclear and radioactive threats to homeland security : prevention and response / Fred L. Wehling and Jeremy Tamsett -- Comparative risk analysis : biological terrorism, pandemics, and other "forgotten" catastrophic disaster threats / Terrence M. O'Sullivan -- Homeland security strategy and policy choices : a local government perspective / Greg Moser -- Democracy, civil society and the damage-limitation component of strategy / Alexander C. Diener and Timothy W. Crawford -- Transportation as a component of homeland security strategy / Joseph S. Szyliowicz -- Redefining U.S. energy security in the twenty-first century / Kevin King -- Afterword: terrorism and securing the homeland / Michael A. Opheim and Nicholas H. Bowen.
  • Section 1. Know the terrorist. Your mission : critical awareness -- Who they are : identify terrorist operatives -- Intelligence profiling suspected terrorists -- Terrorist training -- Terrorism 101 : why the terrorist chooses this path -- What terrorists believe -- Section 2. Identifying the terrorist group and its cells. Terrorist group organization -- The terrorist cell -- Terrorist strategies and target selection -- Section 3. Detection of key terrorist activities. Terrorist preparations for attack : safe houses, finances, and mobility -- The terrorist's tools : conventional weapons identification -- The terrorist's tools : nuclear, biological, chemical weapons and equipment identification -- Section 4. Predicting an attack. Terrorist surveillance techniques -- Detecting infiltration and special mission techniques -- The decision and attack sequence -- The basics of analyzing intelligence and predicting terrorism events -- Point of danger : law enforcement traffic stops and encountering terrorists -- Point of failure : terrorist operations and tactics -- Section 5. The new fields of terror. A primer on Al-Qaeda and the global extremist insurgency -- Suicide terrorism : tactics, equipment and management -- Terrorism and insurgency in the Iraq War (2003-2008) -- Section 6. Supplemental data, bibliography and appendices . Appendix A. Global terrorist groups -- Appendix B. Explosive components & ingredients checklists.
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  • This volume provides a brief resume of the history of testosterone research, from the early pioneers through to the most recent advances in the field. We discover how steroid hormones were first identified and how testosterone was shown to be essential for male development. Moving forward we explore how and where testosterone is produced, and how the body controls testosterone production. We then investigate the impact testosterone has on different body systems both during their development and function, and how perturbation of testosterone action is associated with disease. We complete our story with an exploration of the emerging roles of testosterone in clinical therapy, and the future potential for manipulation of the testosterone signaling system for human health benefit.
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    Intended audience -- Significance -- Roadmap -- General testing format -- Advance notification and disguised tests -- Avoiding false alarms -- Testing levels -- Debriefing procedures -- Staffing and materials -- Choosing a testing agency -- Choosing an appropriate test -- Developing call schedules and background stories -- Trainer responsibilities -- Training session 1: Preparing for a test and debriefing -- Training session 2: Practice and observation -- Initiating a call -- Reaching an action officer -- Debriefing -- Performance criterion -- Generating an after action report -- Continuous quality improvement.
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  • Introduction to the tethered cord syndrome / Shokei Yamada -- Normal spinal cord development and the embryogenesis of spinal cord tethering malformations / Mark S. Dias and Elias B. Rizk -- Pathophysiology of the tethered cord syndrome / Shokei Yamada ... [et al.] -- Neurologic assessment of tethered spinal cord / Sanford Schneider -- Imaging of tethered spinal cord / David B. Hinshaw ... [et al.] -- Ultrasonographic evaluation of tethered cord syndrome / Marvin D. Nelson Jr -- Urological aspect of tethered cord syndrome I : lower urinary tract dysfunction in tethered cord syndrome / H. Roger Hadley ... [et al.] -- Urological aspect of tethered cord syndrome II : clinical experience in urological involvement with tethered cord syndrome / Antoine E. Khoury -- The cervical tethered spinal cord / Kenji Muro, Arthur J. DiPatri Jr., and David G. McLone -- Indication and treatment of tethered spinal cord / James M. Drake and Harold J. Hoffman. Tethered cord syndrome associated with myelomeningoceles and lipomyelomeningoceles / Shokei Yamada ... [et al.] -- The role of folate supplementation in spina bifida occulta / Elias Rizk and Bermans J. Iskandar -- In utero repair of myelomeningoceles / Nalin Gupta -- Epidermoid and dermoid tumors associated with tethered cord syndrome / David S. Knierim, Daniel J. Won, and Shokei Yamada -- Tethered cord syndrome in adult and late-teenage patients without neural spinal dysraphism / Shokei Yamada ... [et al.] -- Tethered cord syndrome in adults with spina bifida occulta / Sharad Rajpal, Samir B. Lapsiwala, and Bermans J. Iskandar -- The normal position of the conus medullaris does not exclude a tethered spinal cord / R. Shane Tubbs and W. Jerry Oakes -- Anomalies of the spinal cord length and filum thickness / Shokei Yamada, Javed Siddiqi, and Shoko M. Yamada -- Intraoperative neurophysiological monitoring of the lower sacral nerve roots and spinal cord / Dachling Pang -- Clinical neurophysiology of tethered cord syndrome and other dysraphic syndromes / Robin L. Gilmore, Sun Ik Lee, and John Walsh -- Conservative versus surgical treatment and prognostic evaluation for tethered cord syndrome / Shokei Yamada ... [et al.].
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  • An historical introduction to porphyrin and chlorophyll synthesis / Michael R. Moore -- Biosynthesis of 5-aminolevulinic acid / Dieter Jahn and Dirk W. Heinz -- 5-aminolaevulinic acid dehydratase, porphobilinogen deaminase and uroporphyrinogen III synthase / Heidi L. Schubert, Peter T. Erskine and Jonathan B. Cooper -- Transformation of uroporphyrinogen III into protohaem / Johanna E. Cornah and Alison G. Smith -- Inherited disorders of haem synthesis: the human porphyrias / Michael N. Badminton and George H. Elder -- Heme degradation: mechanistic and physiological implications / Angela Wilks -- Regulation of mammalian heme biosynthesis / Amy E. Medlock and Harry A. Dailey -- Tetrapyrroles in photodynamic therapy / David I. Vernon and Ian Walker -- Heme transport and incorporation into proteins / Linda Thöny-Meyer -- Heme and hemoproteins / Andrew W. Munro ... [et al.] -- Novel heme-protein interactions: some more radical than others / Ann Smith -- Synthesis and role of bilins in photosynthetic organisms / Nicole Frankenberg-Dinkel and Matthew J. Terry -- Phytochromes: bilin-linked photoreceptors in bacteria and plants / Matthew J. Terry and Alex C. McCormac -- Biosynthesis of chlorophyll and bacteriochlorophyll / Derren J. Heyes and C. Neil Hunter -- Regulation of tetrapyrrole synthesis in higher plants / Matthew J. Terry and Alison G. Smith -- Regulation of the late steps of chlorophyll biosynthesis / Wolfhart Rudiger -- Chlorophyll breakdown / Bernhard Kräutler -- Vitamin B12: biosynthesis of the corrin ring / Ross M. Graham, Evelyne Deery and Martin J. Warren -- Conversion of cobinamide into coenzyme B12 / Jorge C. Escalante-Semerena ... [et al.] -- The regulation of cobalamin biosynthesis / Jeffrey G. Lawrence -- Coenzyme B12-catalyzed radical isomerizations / Dominique Padovani and Ruma Banerjee -- Biosynthesis of siroheme and coenzyme F430 / Martin J. Warren, Evelyne Deery and Ruth-Sarah Rose -- Role of coenzyme F430 in methanogenesis / Evert C. Duin -- The role of siroheme in sulfite and nitrite reductases / M. Elizabeth Stroupe and Elizabeth D. Getzoff -- The role of heme d1 in denitrification / Stuart J. Ferguson.
  • Tetraspanins 2013
    Tetraspanin proteins have recently emerged as a new class of modulators of various processes involving cell surface receptors, including cell migration and invasion, host immune responses, cell-cell fusion, and viral infection. The book summarises recent advances in the fields of biology in which the role of tetraspanins have been established and also covers the molecular evolution of the tetraspanin superfamily and structural aspects of the organisation of tetraspanin microdomains.
  • This book combines clear explanatory text with a wealth of images of ECG recordings in order to provide an accessible, up-to-date source of information and guide to interpretation for all professionals seeking to increase their expertise in electrocardiography. ECG results are presented and discussed for a wide range of conditions, including all forms of arrhythmia, Wolff-Parkinson-White syndrome, bundle branch blocks, ischemic cardiomyopathy, atrial and ventricular enlargement, pericardial and myocardial diseases, diseases of the pulmonary circulation, and post pacemaker implantation. Normal ECG findings are fully described, and helpful introductory information is included on the principles of electrophysiology. The practically oriented text accompanying the ECG recordings covers both electrophysiological and clinical aspects. More than 100 years after its first use by Willem Einthoven, electrocardiography continues to be the first diagnostic tool applied in most cardiac patients. This text atlas provides a sound basis for the correct ECG interpretation essential for appropriate patient management.
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    v. 1. Head and neck -- v. 2. Chest -- v. 3. Abdomen -- v. 4. Bones, joints and soft tissues.
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    v. 1. Principles and methods. Cornea and anterior chamber -- v. 2. Lens and zonule -- v.3. Iris, vitreous body, conjunctiva.
  • Now fully revised and updated, Textbook of Adult Emergency Medicine provides clear and consistent coverage of this rapidly evolving specialty. Building on the success of previous editions, it covers all the major topics that present to the trainee doctor in the emergency department. It will also prove invaluable to the range of other professionals working in this setting - including nurse specialists and paramedics - who require concise, highly practical guidance, incorporating latest best practice and current guidelines. For the first time this edition now comes with a complete and enhanced electronic version, providing a richer learning experience and making rapid reference easier than ever before, anytime, anywhere. Updates throughout reflect latest practice developments, curricula requirements and essential guidelines Key point boxes highlight topic 'essentials' as well as controversial areas of treatment An expanded list of leading international contributors ensures comprehensive coverage and maximizes worldwide relevance New and enhanced coverage of important and topical areas - including latest imaging in emergency medicine; organ donation; massive transfusion protocols; medico legal issues; patient safety and quality measures All new accompanying electronic version, including procedure videos and self-assessment materials to check your understanding and aid exam preparation.
  • Angiogenesis and lymphangiogenesis have become attractive targets for drug therapy because of their key roles in a broad spectrum of pathological disease states ranging from macular degeneration to tumor growth and metastasis. A substantial increase in the research effort over the past decade has deepened our understanding of the basic mechanisms underlying angiogenesis and lymphangiogenesis, promoting the development of promising therapeutics for the clinical management of vascular-related diseases.
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    Part I: Structure of macromolecules -- 1. Eukaryotic Cell Structure -- 2. DNA and RNA: Composition and Structure -- 3. Proteins I: Composition and Structure -- Part II: Transmission of information -- 4. DNA Replication, Recombination, and Repair -- 5. RNA: Transcription and RNA Processing -- 6. Protein Synthesis: Translation and Posttranslational Modifications -- 7. Recombinant DNA and Biotechnology -- 8. Regulation of Gene Expression -- Part III: Functions of proteins -- 9. Proteins II: Structure-Function Relationships in Protein Families -- 10. Enzymes: Classification, Kinetics, and Control -- 11. The Cytochromes P450 and Nitric Oxide Synthases -- 12. Biological Membranes: Structure, Receptors, and Solute Transport -- 13. Fundamentals of Signal Transduction -- Part IV: Metabolic pathways and their control -- 14. Bioenergetics, Mitochondria, and Oxidative Metabolism -- 15. Carbohydrate Metabolism I: Major Metabolic Pathways and Their Control -- 16. Carbohydrate Metabolism II: Special Pathways and Glycoconjugates -- 17. Lipid Metabolism I: Synthesis, Storage, and Utilization of Fatty Acids and Triacylglycerols -- 18. Lipid Metabolism II: Pathways of Metabolism of Special Lipids -- 19. Amino Acid and Heme Metabolism -- 20. Purine and Pyrimidine Nucleotide Metabolism -- 21. Metabolic Interrelationships -- 22. Biochemistry of Hormones -- Part V: Physiological processes -- 23. Molecular Cell Biology -- 24. Cell Cycle, Programmed Cell Death, and Cancer -- 25. Digestion and Absorption of Basic Nutritional Constituents -- 26. Vitamins and Minerals: Requirements and Function -- 27. Macronutrients: Metabolic Effects and Health Implications -- Appendix: Review of Organic Chemistry -- Glossary -- Index.
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    Part I. Background -- Accomplishments in cancer epidemiology / Brian MacMahon -- Measures and estimates of cancer burden / Pagona Lagiou, Johanna Adami, and Dimitrios Trichopoulos -- The origin of cancer /Jeffrey Ecsedy and David Hunter -- Genetic epidemiology of cancer / Christopher Haiman and David Hunter -- Biomarkers in cancer epidemiology / Paolo Boffetta and Dimitrios Trichopoulos -- Concepts in cancer epidemiology and etiology / Pagona Lagiou, Dimitrios Trichopoulos, and Hans-Olov Adami -- Part II. Cancer epidemiology by site-specific cancers -- Oral and pharyngeal cancer / Paul Brennan, Lorelei Mucci, and Hans-Olov Adami -- Nasopharyngeal carcinoma / Ellen Chang and Hans-Olov Adami -- Esophageal cancer / Olof Nyrén and Hans-Olov Adami -- Stomach cancer / Olof Nyrén and Hans-Olov Adami -- Colorectal cancer / John D. Potter and David Hunter -- Cancer of the liver and biliary tract / Sherri Stuver and Dimitrios Trichopoulos -- Pancreatic cancer / Anders Ekbom and Dimitrios Trichopoulos -- Cancer of the lung, larynx, and pleura / Paolo Boffetta and Dimitrios Trichopoulos -- Skin cancer / Adèle Green, Jolieke van der Pols, and David Hunter -- Breast cancer / Susan Hankinson, Rulla Tamimi, and David Hunter -- Cervical cancer / Nathalie Ylitalo, Sherri Stuver, and Hans-Olov Adami -- Endometrial cancer / Immaculata DeVivo, Ingemar Persson, and Hans-Olov Adami -- Ovarian cancer / Penelope Webb, Dorota Gertig, and David Hunter -- Prostate cancer / Lorelei A. Mucci, Lisa B. Signorello, and Hans-Olov Adami -- Testicular cancer / Lorenzo Richiardi, Rulla Tamimi, and Hans-Olov Adami -- Urinary bladder cancer / Manolis Kogevinas, Montserrat Garcia-Closas, and Dimitrios Trichopoulos -- Kidney cancer / Eunyoung Cho, Per Lindblad, and Hans-Olov Adami -- Brain cancer / David A. Savitz and Dimitrios Trichopoulos -- Thyroid cancer / Per Hall and Hans-Olov Adami -- Hodgkin lymphoma / Mads Melbye, Henrik Hjalgrim, and Hans-Olov Adami -- Non-hodgkin lymphoma / Mads Melbye, Karin Ekström Smedby, and Dimitrios Trichopoulos -- Leukemias / Eleni Petridou, Apostolos Pourtsidis, and Dimitrios Trichopoulos.
  • Catheter-based interventions have evolved to address a variety of needs through innovation and clinical evidence.The field of interventional cardiology and interventional vascular medicine now comprises the dominant diagnostic and therapeutic field within cardiovascular medicine, and continues to grow in terms of patients managed and physicians trained. Given the vast expansion of technologies, techniques, and the clinical evidence base, it can be challenging for the practicing clinician, fellow-in-training, or technology developer to maintain general knowledge of the interventional cardiovascular field.The Textbook of Cardiovascular Intervention is intended to provide a practical, comprehensive and compact text on interventional cardiology for the current, rapidly evolving practice environment. It will appeal to fellows, residents and physicians in cardiology, interventional cardiology, cardiothoracic and vascular surgery, vascularand endovascular medicine, neurointerventional radiology and surgery, emergency medicine and intensive care.
  • Atherosclerotic biology and epidemiology of disease -- Diet and nutritional issues -- Obesity and metabolic syndrome -- Diabetes -- Lipid disorders -- Exercise and physical activity -- Hypertension: context and management -- Smoking -- Estrogen, female gender, and heart disease -- Ethanol and the heart -- Other risk factors for coronary artery disease -- Behavioral cardiology and heart disease -- Cardiac rehabilitation and secondary prevention -- An integrated approach to risk factor modification -- The history -- Physical examination -- Chronic stable coronary disease -- Unstable angina: ischemic syndromes -- Acute myocardial infarction: early diagnosis and management -- Acute myocardial infarction: complications -- Post-Myocardial infarction management -- Mitral valve disease -- Aortic valve disease -- Acquired tricuspid and pulmonary valve disease -- Prosthetic valve disease -- Infective endocarditis -- Diseases of the pericardium, restrictive cardiomyopathy, and diastolic dysfunction -- Pulmonary hypertension -- Hypertrophic cardiomyopathy -- Congenital heart disease -- The heart and pregnancy -- Women and heart disease -- The elderly and aging -- End-of-life care -- The heart and other organ systems -- Endocrine systems and the heart -- Hematologic disorders and the heart -- The heart and the renal system -- Cardiac manifestations of selected neurologic disorders -- Cardiovascular manifestations of rheumatic diseases -- The heart and infectious diseases -- Substance abuse and the heart -- The athlete's heart -- Cardiac trauma -- Cardiac tumors -- Clinical pharmacology for the cardiologist -- Perioperative anesthetic considerations in noncardiac surgery for those at high risk of cardiovascular disease -- Medical economics in cardiovascular medicine -- Considerations in the design, conduct, and interpretation of quantitative clinical evidence -- Databases in cardiology -- Quality of care and medical errors in cardiovascular disease -- Principles of imaging -- Plain film examination of the chest -- Exercise electrocardiography -- Transthoracic echocardiography -- Stress echocardiography -- Doppler echocardiography -- Transesophageal echocardiography -- Imaging techniques in nuclear cardiology -- Cardiovascular magnetic resonance imaging -- Positron emission tomography -- Computed tomography of the heart -- Mechanisms of cardiac arrhythmias -- Genetics of arrhythmias -- Electrocardiography -- Ambulatory and signal-averaged electrocardiography and t-wave alternans -- Electrophysiologic testing -- Bradycardias: sinus nodal dysfunction and atrioventricular conduction disturbances -- Atrial fibrillation -- Atrial flutter -- Atrioventricular nodal-dependent tachycardias and preexcitation -- Ventricular tachycardia -- Sudden cardiac death and implantable cardioverter-defibrillators -- Sudden cardiac death in the young: the impact of inherited cardiovascular disease -- Cardiopulmonary resuscitation -- Arrhythmias in congenital heart disease -- Syncope -- Antiarrhythmic drugs -- Catheter ablation therapy for arrhythmias -- Cardiac pacemakers -- Left ventricular dyssynchrony and cardiac resynchronization therapy-- Coronary angiography -- Cardiac catheterization and hemodynamic assessment -- Percutaneous coronary intervention -- Percutaneous cardiac procedures -- Coronary artery bypass surgery -- Approaches to the patient with prior bypass surgery -- Percutaneous valve dilatations -- Catheter interventions in congenital heart disease -- Global pandemic of heart failure -- Pathophysiology of the heart failure clinical syndrome -- Acute heart failure -- Chronic heart failure management -- Diagnosis and medical treatment of inflammatory cardiomyopathy -- Nonischemic cardiomyopathies -- Cardiac transplantation and mechanical circulatory support -- surgical approaches for heart failure -- Prevention of heart failure -- General techniques in molecular cardiology -- Molecular genetics -- Genetic factors in atherosclerosis -- Genetic studies of myocardial and vascular disease -- Gene therapy -- Myocyte structure and function -- Signal transduction pathways of the heart -- Molecular basis of heart development -- Stem cell therapy for ischemic heart disease -- The biology of restenosis -- Therapeutic angiogenesis -- Diseases of the pulmonary vasculature -- Diseases of the aorta -- Noninvasive assessment of peripheral vascular disease -- Cerebrovascular disease -- Disease of peripheral vessels -- Renal artery disease -- Venous thromboembolism.
  • This 5th Edition enables you to use echocardiography to its fullest potential in your initial diagnosis, decision making, and clinical management of patients with a wide range of heart diseases. World-renowned cardiologist Dr. Catherine M. Otto helps you master what you need to know to obtain the detailed anatomic and physiologic information that can be gained from the full range of echo techniques, from basic to advanced. Acquire a solid foundation in the essentials of advanced echocardiography techniques such as contrast echo, 3D echo, myocardial mechanics, and intraoperative transesophageal echocardiography. Fully understand the use of echocardiography and its outcomes with key points that identify the must-know elements in every chapter, and state-of-the-art echo images complemented by full-color comparative drawings of heart structures. Familiarize yourself with new ASE recommendations for echocardiographic assessment of the right heart and 3D echocardiography, including updated tables of normal measurements.
  • "The success of Assisted Reproductive Technology is critically dependent upon the use of well optimized protocols, based upon sound scientific reasoning, empirical observations and evidence of clinical efficacy. Recently, the treatment of infertility has experienced a revolution, with the routine adoption of increasingly specialized molecular biological techniques and advanced methods for the manipulation of gametes and embryos. This textbook - inspired by the postgraduate degree program at the University of Oxford - guides students through the multidisciplinary syllabus essential to ART laboratory practice, from basic culture techniques and micromanipulation to laboratory management and quality assurance, and from endocrinology to molecular biology and research methods. Written for all levels of IVF practitioners, reproductive biologists and technologists involved in human reproductive science, it can be used as a reference manual for all IVF labs and as a textbook by undergraduates, advanced students, scientists and professionals involved in gamete, embryo or stem cell biology"--Provided by publisher.
  • Introduction to hemodynamic assessment in the cardiac catheterization laboratory / Michael Ragosta -- Normal waveforms, artifacts, and pitfalls / Michael Ragosta -- Cardiac outputs and shunts / Vishal Aurora -- Mitral valve disorders / Michael Ragosta -- Aortic valve disease / Michael Ragosta -- Hypertrophic cardiomyopathy and related conditions / Michael Ragosta -- Right-sided heart disorders: hemodynamics of the tricuspid and pulmonic valves and pulmonary hypertension / Michael Ragosta -- Pericardial disease and restrictive cardiomyopathy / Michael Ragosta -- Shock, heart failure, and related disorders / Michael Ragosta -- Complications of acute myocardial infarction / Brandon Brown -- Congenital heart disease / Rajan A.G. Patel and D. Scott Lim -- Coronary hemodynamics / Michael Ragosta -- Advanced hemodynamic assessment of ventricular function / D. Scott Lim and Howard P. Gutgesell -- Miscellaneous hemodynamic conditions / Michael Ragosta.
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    Principles and practice -- Work sectors and special populations -- Occupational diseases and injuries -- Hazards in the workplace and the environment -- Policy, regulation and control.
  • V. 1, section 1. Genetic disorders / Bruce R. Korf ; section 2. Neonatology / Martin Keszler ; section 3. Inborn errors of metabolism / Pinar T. Ozand ; section 4. Developmental, learning and behavioral disorders / Pamela High and Yvette Yatchmink -- v. 2, section 5. Pediatric nutrition / Hisham M. Nazer ; section 6. Infectious diseases / Richard J. Whitley ; section 7. Primary immunodeficiency disorders / Harb A. Harfi ; section 8. Allergic disorders / Harb A. Harfi -- v. 3, section 9. Disorders of the skin / Zbigniew Ruszczak ; section 10. Rheumatology / Alberto Martini ; section 11. Oral and craniofacial disorders / J. Burton Douglass ; section 12. Gastrointestinal and liver disorders / Hisham M. Nazer -- v. 4, section 13. Respiratory disorders / Gabriel G. Haddad ; section 14. Cardiology / Mark B. Lewin ; section 15. Critical care / Abdul-Rahman M. Abu-Taleb and Peter N. Cox ; section 16. Pediatric burns / Fuad Hashem ; section 17. Pediatric poisoning / Khaled M. Al-Haidari and Nada S. Al-Qadheeb ; section 18. Disturbances in acid-base and electrolytes disorders / F. Bruder Stapleton ; section 19. Kidney and urinary tract disorders / F. Bruder Stapleton -- v. 5, section 19. Kidney and urinary tract disorders / F. Bruder Stapleton ; section 20. Blood diseases / Michael Recht ; section 21. Pediatric oncology / H. Stacy Nicholson ; section 22. Neurology / Generoso G. Gascon -- v. 6, section 22. Neurology / Generoso G. Gascon ; section 23. Endocrine disorders / Khalid Hussain ; section 24. Adolescent medicine / Leslie R. Walker ; section 25. Pediatric orthopedics / Craig P. Eberson ; section 26. Pediatric otolaryngology / Mohamed O. Abuzeid ; section 27. Pediatric ophthalmology / Selwa A.F. Al-Hazzaa ; section 28. Pediatric surgery / Thomas F. Tracy ; section 29. Drug dosing in pediatrics / Kristine A. Parbuoni.
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  • This reference - acclaimed for its success in bridging the gap between medical and surgical critical care - now features an even stronger focus on patient outcomes, equipping you with the proven, evidence-based guidance you need to successfully overcome a full range of practice challenges. Inside, you'll find totally updated coverage of vital topics, such as coagulation and apoptosis in certain critical care illnesses, such as acute lung injury and adult respiratory distress syndrome; sepsis and other serious infectious diseases; specific organ dysfunction and failure; and many other vital topics. Effectively apply the latest techniques and approaches with totally updated coverage of the importance of coagulation and apoptosis in certain critical care illnesses, such as acute lung injury and adult respiratory distress syndrome; sepsis and other serious infectious diseases; specific organ dysfunction and failure; and many other vital topics.
  • Synopsis: Stay up to date with the rapidly changing field of medical sonography! Heavily illustrated and extensively updated to reflect the latest developments in the field, Textbook of Diagnostic Sonography, 7th Edition equips you with an in-depth understanding of general/abdominal and obstetric/gynecologic sonography, the two primary divisions of sonography, as well as vascular sonography and echocardiography. Each chapter includes patient history, normal anatomy (including cross-sectional anatomy), ultrasound techniques, pathology, and related laboratory findings, giving you comprehensive insight drawn from the most current, complete information available. Full-color presentation enhances your learning experience with vibrantly detailed images. Pathology tables give you quick access to clinical findings, laboratory findings, sonography findings, and differential considerations. Sonographic Findings highlight key clinical information. Key terms and chapter objectives help you study more efficiently. Review questions on a companion Evolve website reinforce your understanding of essential concepts. New chapters detail the latest clinically relevant content in the areas of: Essentials of Patient Care for the Sonographer; Artifacts in Image Acquisition; Understanding Other Imaging Modalities; Ergonomics and Musculoskeletal Issues in Sonography; 3D and 4D Evaluation of Fetal Anomalies; More than 700 new images (350 in color) clarify complex anatomic concepts. Extensive content updates reflect important changes in urinary, liver, musculoskeletal, breast, cerebrovascular, gynecological, and obstetric sonography.
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    The origins of family medicine -- Principles of family medicine -- Illness in the community -- A profile of family practice -- Philosophical and scientific foundations of family medicine -- Illness, suffering, and healing -- Doctor-patient communication -- Clinical method -- The enhancement of health and the prevention of disease -- The family in health and disease -- Acute sore throat -- Headache -- Fatigue -- Hypertension -- Diabetes -- Home care -- Records -- Consultation and referral -- The health professions -- The community service network -- Alternative or complementary medicine -- Practice management -- Continuing self-education -- Research in family practice.
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  • This ninth edition of the Textbook of Family Medicine, edited by Drs. Robert E. Rakel and David P. Rakel, remains your #1 choice for complete guidance on the principles of family medicine, primary care in the community, and all aspects of clinical practice. Ideal for both residents and practicing physicians, this medical reference book includes evidence-based, practical information to optimize patient care and prepare you for the ABFM exam. A clean, quick-reference layout makes it easy for you to put information to work immediately in your practice.
  • Imaging contrast agents and pharmacoradiology -- Barium studies : single and double contrast -- Pictorial glossary of double-contrast radiology -- Ultrasound of the hollow viscera -- Multidetector computed tomography of the gastrointestinal tract : principles of interpretation -- Magnetic resonance imaging of the hollow viscera -- Positron emission tomography and computed tomography of the hollow viscera -- Angiography and interventional radiology of the hollow viscera -- Abdominal computed tomography angiography -- Magnetic resonance angiography of the mesenteric vasculature -- Abdomen : normal anatomy and examination techniques -- Gas and soft tissue abnormalities -- Abdominal calcifications -- Pharynx : normal anatomy and examination techniques -- Abnormalities of pharyngeal function -- Structural abnormalities of the pharynx -- Barium studies of the upper gastrointestinal tract -- Motility disorders of the esophagus -- Gastroesophageal reflux disease -- Infectious esophagitis -- Other esophagitides -- Benign tumors of the esophagus -- Carcinoma of the esophagus -- Other malignant tumors of the esophagus -- Miscellaneous abnormalities of the esophagus -- Abnormalities of the gastroesophageal junction -- Postoperative esophagus -- Esophagus : differential diagnosis -- Peptic ulcers -- Inflammatory conditions of the stomach and duodenum -- Benign tumors of the stomach and duodenum -- Carcinoma of the stomach and duodenum -- Other malignant tumors of the stomach and duodenum -- Miscellaneous abnormalities of the stomach and duodenum -- Postoperative stomach and duodenum -- Stomach and duodenum : differential diagnosis -- Barium examinations of the small intestine -- Computed tomography enterography -- Computed tomography enteroclysis -- Magnetic resonance enterography -- Crohn's disease of the small bowel -- Inflammatory disorders of the small bowel other than Crohn's disease -- Malabsorption -- Benign tumors of the small bowel -- Malignant tumors of the small bowel -- Small bowel obstruction -- Vascular disorders of the small intestine -- Postoperative small bowel -- Miscellaneous abnormalities of the small bowel -- Small intestine : differential diagnosis -- Barium studies of the colon -- Functional imaging of anorectal and pelvic floor dysfunction -- Computed tomography colonography -- Magnetic resonance colonography -- Diverticular disease of the colon -- Diseases of the appendix -- Ulcerative and granulomatous colitis : idiopathic inflammatory bowel disease -- Other inflammatory conditions of the colon -- Polyps and colon cancer -- Other tumors of the colon -- Polyposis syndromes -- Miscellaneous abnormalities of the colon -- Postoperative colon -- Colon : differential diagnosis -- Computed tomography of the solid abdominal organs -- Ultrasound examination of the solid abdominal viscera -- Magnetic resonance imaging of the solid parenchymal organs -- Positron emission tomography/computed tomography of the solid parenchymal organs -- Diffusion-weighted imaging of the abdomen -- Perfusion computed tomography and magnetic resonance imaging in the abdomen and pelvis -- Techniques of percutaneous tissue acquisition -- Abdominal abscess -- Gallbladder and biliary tract : normal anatomy and examination techniques -- Endoscopic retrograde cholangiopancreatography -- Magnetic resonance cholangiopancreatography -- Anomalies and anatomic variants of the gallbladder and biliary tract -- Cholelithiasis, cholecystitis, choledocholithiasis, and hyperplastic cholecystoses -- Interventional radiology of the gallbladder and biliary tract -- Neoplasms of the gallbladder and biliary tract -- Inflammatory disorders of the biliary tract -- Postsurgical and traumatic lesions of the biliary tract -- Gallbladder and biliary tract : differential diagnosis -- Liver : normal anatomy and examination techniques -- Interventional radiology of the liver -- Anomalies and anatomic variants of the liver -- Benign tumors of the liver -- Malignant tumors of the liver -- Focal hepatic infections -- Diffuse liver disease -- Vascular disorders of the liver and splanchnic circulation -- Hepatic trauma, surgery, and liver-directed therapy -- Liver transplantation imaging -- Liver : differential diagnosis -- Pancreas : normal anatomy and examination techniques -- Interventional radiology of the pancreas -- Anomalies and anatomic variants of the pancreas -- Pancreatitis -- Pancreatic neoplasms -- Pancreatic trauma and surgery -- Pancreatic transplantation imaging -- Pancreas : differential diagnosis -- Spleen : normal anatomy and examination techniques -- Angiography and interventional radiology of the spleen -- Anomalies and anatomic variants of the spleen -- Benign and malignant lesions of the spleen -- Splenic trauma and surgery -- Spleen : differential diagnosis -- Anatomy and imaging of the peritoneum and retroperitoneum -- Pathways of abdominal and pelvic disease spread -- Ascites and peritoneal fluid collections -- Mesenteric and omental lesions -- Hernias and abdominal wall pathology -- Applied embryology of the gastrointestinal tract -- Neonatal gastrointestinal radiology -- Diseases of the pediatric esophagus -- Diseases of the pediatric stomach and duodenum -- Diseases of the pediatric small bowel -- Diseases of the pediatric colon -- Diseases of the pediatric gallbladder and biliary tract -- Diseases of the pediatric liver -- Diseases of the pediatric pancreas -- Diseases of the pediatric spleen -- Diseases of the pediatric abdominal wall, peritoneum, and mesentery -- The acute abdomen -- Gastrointestinal hemorrhage -- Abdominal trauma -- Monitoring gastrointestinal tumor response to therapy.
  • Hand eczema is a major complaint worldwide and a frequent occupational disorder. This book provides a comprehensive and detailed overview of the classification, etiology, diagnosis, prevention, and therapy of hand eczema. It is innovative, up to date, and practical. The links with particular occupations are explained, the various diagnostic tests are presented, and the role of different topical and systemic treatments is clearly described. The authors are world leaders in the field. The Textbook of Hand Eczema reflects a new era in hand dermatitis and will be invaluable for all who deal with the condition in their clinical practice.
  • Influenza: perspective -- Human influenza: one health, one world -- Influenza pandemics: history and lessons learned -- Structure and replication -- Structure, disassembly, assembly, and budding of influenza viruses -- The virus genome and its replication -- Influenza glycoproteins: hemagglutinin and neuraminidase -- Proton channels of influenza A and B viruses -- The NS1 protein: a master regulator of host and viral functions -- Structure and function of the influenza virus replication machinery and PB1-F2 -- The genome and its manipulation: recovery of the 1918 virus and vaccine virus generation -- Pathogenesis -- Evolution and ecology of influenza viruses -- Ecology and evolution of influenza viruses in wild and domestic birds -- Influenza in swine -- Equine/canine/feline/seal influenza -- Emergence and evolution of the 1918, 1957, 1968, and 2009 pandemic virus strains -- Epidemiology and surveillance -- Influenza surveillance and laboratory diagnosis -- Epidemiology of influenza -- Immunology of influenza -- Innate immunity -- Antibody-mediated immunity -- Cell-mediated immunity -- Vaccines and vaccine development -- Immunogenicity, efficacy of inactivated/live virus seasonal and pandemic vaccines -- New approaches to vaccination -- Control of influenza in animals -- Influenza vaccine production -- Clinical aspects and antivirals -- Human influenza: pathogenesis, clinical features, and management -- Antivirals: targets and use -- The control of influenza and cost-effectiveness of interventions -- Applications of quantitative modeling to influenza virus transmission dynamics, antigenic and genetic evolution, and molecular structure -- Pandemic preparedness and response -- Influenza: the future -- The outbreak of H7N9.
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    Evolution of integrative medicine and implications for mental health care -- Philosophical problems -- Paradigms in medicine, psychiatry, and integrative medicine -- Foundations of clinical methodology in integrative medicine -- History taking, assessment, formulation in integrative mental health care -- Starting and maintaining integrative treatment in mental health care -- Symptom-focused integrative mental health care -- Integrative management of depressed mood -- Integrative management of mania and cyclic mood changes -- Integrative management of anxiety -- Integrative management of psychosis -- Integrative management of dementia and mild cognitive impairment -- Integrative management of substance abuse and dependence -- Integrative management of disturbances of sleep and wakefulness.
  • "The Textbook of Interdisciplinary Pediatric Palliative Care, by Drs. Joanne Wolfe, Pamela Hinds, and Barbara Sourkes, aims to inform interdisciplinary teams about palliative care of children with life-threatening illness. It addresses critical domains such as language and communication, symptoms and quality of life, and the spectrum of life-threatening illnesses in great depth. This comprehensive product takes a first-of-its-kind team approach to the unique needs of critically ill children. It shows how a collaborative, interdisciplinary care strategy benefits patients and their families. If you deal with the complex care of critically ill children, this reference provides a uniquely integrated perspective on complete and effective care."--Publisher's website.

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A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available. 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