BookAntonio Russo, Rafael Rosell, Christian Rolfo, editors.
Summary: This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.
Contents:
Introduction
Oncogene Addiction in Solid Tumors
Pharmacology and Clinical Development of New Molecularly Targeted Agents
Biomarkers as Prognostic, Predictive and Surrogate Endpoints
Evaluation of Response in Malignant Tumors Treated with Targeted Agents
Targeted Therapies for HER2-Positive Breast Cancer
Role of PARP Inhibitors in Triple Negative Breast Cancer (TNBC)
Targeted Therapies in Squamous Cell Carcinoma of the Head and Neck
Targeted Therapies for NSCLC
Targeted Therapies for Gastric Cancer
Targeted Therapies for Pancreatic Cancer
Targeted Therapies in Hepatocellular Carcinoma
Targeted Therapies for Colorectal Cancer
Targeted Therapy in Gastrointestinal Stromal Tumors
Targeted Therapies in Kidney Cancer
Targeted Therapies in Melanoma
Targeted Therapies for Prostate Cancer
Targeted Therapies for Bone Metastases.