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  • Book
    Antonio Russo, Rafael Rosell, Christian Rolfo, editors.
    Summary: This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.

    Contents:
    Introduction
    Oncogene Addiction in Solid Tumors
    Pharmacology and Clinical Development of New Molecularly Targeted Agents
    Biomarkers as Prognostic, Predictive and Surrogate Endpoints
    Evaluation of Response in Malignant Tumors Treated with Targeted Agents
    Targeted Therapies for HER2-Positive Breast Cancer
    Role of PARP Inhibitors in Triple Negative Breast Cancer (TNBC)
    Targeted Therapies in Squamous Cell Carcinoma of the Head and Neck
    Targeted Therapies for NSCLC
    Targeted Therapies for Gastric Cancer
    Targeted Therapies for Pancreatic Cancer
    Targeted Therapies in Hepatocellular Carcinoma
    Targeted Therapies for Colorectal Cancer
    Targeted Therapy in Gastrointestinal Stromal Tumors
    Targeted Therapies in Kidney Cancer
    Targeted Therapies in Melanoma
    Targeted Therapies for Prostate Cancer
    Targeted Therapies for Bone Metastases.
    Digital Access Springer 2015