BookNima Rezaei, editor.
Summary: This translational, clinically oriented book describes in detail novel approaches to cancer immunotherapy, current strategies to target tumor immunosuppression, and prognostic biomarkers for personalized cancer treatments. Since the first, very successful edition of the book was published in 2015, the original chapters have been significantly updated and entirely new chapters are included on, for example, cancer immunoprevention, aptamer-mediated cancer gene therapy, haploidentical bone marrow transplantation for pediatric malignancies, and nanoimmunotherapy. The book is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Other volumes in the series address the translational medicine context and cancer immunotherapy for organ-specific tumors. Cancer Immunology: Bench to Bedside Immunotherapy of Cancers will be of special value to clinical immunologists, hematologists, and oncologists.
Contents:
Frontiers in Cancer Immunotherapy
Novel Strategy of Cancer Immunotherapy: Spiraling Up
Novel Prognostic Biomarkers for Personalized Cancer Treatments
Tumor Antigen and Epitope Identification for Pre-Clinical and Clinical Evaluation
Strategies to Target Tumor Immunesuppression
Immune Modulation of Drugs in Prevention and Treatment of Cancers
Overcoming Immune Tolerance With Immune Checkpoint Blockade
Gene therapy and Virus-Based Cancer Vaccines
Cancer Stem Cells: Biology and Potential therapeutic Applications
Hematopoietic Stem Cell Transplantation and Lymphodepletion in Treatment of Cancers
Combination of Chemotherapy and Cytokine Therapy in Treatment of Cancers
T Cell Immunotherapy: From Synthetic Biology to Clinical Practice
Role of Gamma-Delta T Lymphocytes in Cancer Immunosurveillance and Immunotherapy
Adoptive T Cell therapy: Optimizing Chemokine Receptor-Mediated Homing of T Cells in Cancer Immunotherapy
Cellular therapy of Cancer With B Effector Cells
Monoclonal Antibodies for Treatment of Cancers
Pattern Recognition Receptors in Cancers and Immunotherapy by Triggering or Targeting of Toll Like Receptors Pathway
Recent Advances in the Use of NK Cells Against Cancer
Dendritic Cell Vaccines for Cancer Therapy: Fundamentals and Clinical Trials
Tumor Associated Macrophages and iNOS in Cancer Immunotherapy
Photodynamic therapy and Anti-Tumor Immune Response
Polarization of Tumor Milieu: Therapeutic Implications
Immunotherapies Targeting 5T4 Oncofoetal Glycoprotein
Immune Monitoring During Clinical Development of Anti-CTLA-4 Antibody Therapy
PD-1 Blockade in Cancer Therapy
New Advances in Radioimmunotherapy for the Treatment of Cancers
Psychoneuroendocrinoimmunotherapy of Cancers
Ethical Considerations in Cancer Immunotherapy.