BookKeith C. Ferdinand, Herman A. Taylor, Jr., Carlos J. Rodriguez, editors.
Summary: The book discusses the impact of genetics, social determinants of health, the environment, and lifestyle in the burden of cardiometabolic conditions in African American and Hispanic/Latinx populations. It includes fully updated and revised chapters on genetics and CVD risk, epidemiology of cardiovascular health, cardiovascular imaging, dyslipidemias and other emerging risk factors, obesity and metabolic syndrome, heart failure, and genetic variations in CVD. Unique aspects within African American and Hispanic/Latinx populations are explored with suggested appropriate therapeutic interventions. New chapters focus on ASCVD risk assessment, emerging precision medicine concepts, the impact of diabetes, resilience and CVD survival, and lifestyle and dieting considerations. Written by a team of experts, the book examines the degree to which biomedical and scientific literature can clarify the impact of genetic variation and environment on cardiovascular disease. The Second Edition of Cardiovascular Disease in Racial and Ethnic Minority Populations is an essential resource for physicians, residents, fellows, and medical students in cardiology, internal medicine, family medicine, clinical lipidology, and epidemiology.
Contents:
Intro
Preface
References
Contents
Contributors
1: Overview and Perspectives: Cardiovascular Disease in Racial/Ethnic Minorities in the Era of COVID-19
Introduction
Introduction to Precision Medicine: Minority Populations and Cardiovascular Health
Lipoprotein(a): A Cardiovascular Risk Factor Affecting Ethnic Minorities
Emerging Precision Medicine Concepts and Cardiovascular Health in African Americans and Hispanics
The Implementation Frontier: Impact on Cardiovascular Health in Racial and Ethnic Minority Populations
Genomic Approaches to Hypertension Heart Failure in African Americans and Hispanic Americans: A Persistent and Disproportionate Burden in Underrepresented Minorities
Heterogeneity, Nativity, and Disaggregation of Cardiovascular Risk and Outcomes in Hispanic Americans
Cardiovascular Epidemiology in Hispanics/Latinos: Lessons Learned from HCHS/SOL
Lessons Learned from the Jackson Heart Study (JHS)
Cardiovascular Disease Risk Factors in the Hispanic/Latino Population
Progress in ASCVD Risk Assessment in African American and Hispanics Cardiovascular Disease in Minorities: Unique Considerations Hypertension in African and Hispanic Americans
Weight Loss, Lifestyle, and Dietary Factors in CVD in African Americans and Hispanics
Coronary Calcium Scoring in African American and Hispanic Patients
Epidemiology CVD in African Americans
Cardiac Amyloid Heart Disease in Racial/Ethnic Minorities: Focus on Transthyretin Amyloid Cardiomyopathy
Imaging for the Assessment and Management of Cardiovascular Disease in Women and Minority Populations
References 2: Introduction to Precision Medicine: Minority Populations and Cardiovascular Health
An Introduction to Genomic Testing
Diagnostic Genetic Testing for Heart Disease
Advances in Genetic Testing
Development of Genetic Tests as an Evidence-Based Process
Lack of Diversity in Genetic Research and the Missing Evidence Supporting Generalizability of Genetic Tests
Impaired Discovery of Genetic Causes in Minority Populations
Misdiagnosis of Genetic Conditions in Minority Populations
Unclear Treatment Response in Minority Populations Unclear Validity and Utility of Individual Genetic Tests in Minority Populations
Understanding the Personal Utility of Genetic Tests in Minority Populations
Access to Precision Medicine and the Health Disparities
On the Horizon
The Road Forward
References
3: Lipoprotein(a): A Cardiovascular Risk Factor Affecting Ethnic Minorities
Introduction to Lipoprotein(a)
References
4: Emerging Precision Medicine Concepts and Cardiovascular Health in African Americans and Hispanics
Introduction
Race, Ethnicity, and Genetic Ancestry