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  • Book
    Nima Rezaei, editor.
    Summary: "This book focusing on the immunopathology of cancers is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Readers will find detailed descriptions of the interactions between cancerous cells and various components of the innate and adaptive immune system. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the latest research and novel developments in the field. In the new edition of this very well received book, first published in 2015, the original chapters have been significantly updated and additional chapters included on, for example, current knowledge on the roles of T-helper cells and NK cells in tumor immunity, the part played by oncoviruses in the development of various cancers, and the applications of fluorescent in situ hybridization, bioluminescence, and cancer molecular and functional imaging"--Publisher's description.

    Contents:
    Introduction on cancer immunology and immunotherapy
    Role of innate immunity in cancers and antitumor response
    Tumor-associated myeloid cells in cancer progression
    B-cells in cancer immunology: for or against cancer growth?
    The roles of CD4+ T-cells in tumor immunity
    Regulatory T-cells and Th cells in tumor microenvironment
    T-cell metabolism and its dysfunction induced by cancer
    The role of exhaustion in tumor-induced T-cell dysfunction in cancer
    The role of NK cells in cancer
    Role of plasmacytoid dendritic cells in cancer
    The CD95/CD95L signaling pathway: a role in carcinogenesis
    MHC class I molecules and cancer progression: lessons learned from preclinical mouse models
    Role of cytokines in tumor immunity and immune tolerance to cancer
    Role of chemokines and chemokine receptors in cancer
    Role of the inflammasome in cancer
    Cancer immunoediting: immunosurveillance, immune equilibrium, and immune escape
    Apoptosis and cancer
    Endoplasmic reticulum stress and autophagy in cancer
    Prognostic value of innate and adaptive immunity in cancers
    Immunogenetics of cancer
    Epigenetics and MicroRNAs in cancer
    The role of DNA methylation in cancer
    Immunosenescence, oxidative stress, and cancers
    Nutrition, immunity, and cancers
    Inborn errors of immunity and cancers
    Allergies and cancers
    Envisioning the application of systems biology in cancer immunology
    Principles of immunological diagnostic tests for cancers
    Immunohistochemistry of cancers
    Fluorescent in situ hybridization: methods and application in cancer diagnosis
    Cancer molecular and functional imaging
    Cancer imaging with radiolabeled monoclonal antibodies
    Flow cytometry in cancer immunotherapy: applications, quality assurance, and future.
    Digital Access Springer 2020