BookNima Rezaei, editor.
Summary: "This book focusing on the immunopathology of cancers is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Readers will find detailed descriptions of the interactions between cancerous cells and various components of the innate and adaptive immune system. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the latest research and novel developments in the field. In the new edition of this very well received book, first published in 2015, the original chapters have been significantly updated and additional chapters included on, for example, current knowledge on the roles of T-helper cells and NK cells in tumor immunity, the part played by oncoviruses in the development of various cancers, and the applications of fluorescent in situ hybridization, bioluminescence, and cancer molecular and functional imaging"--Publisher's description.
Contents:
Introduction on cancer immunology and immunotherapy
Role of innate immunity in cancers and antitumor response
Tumor-associated myeloid cells in cancer progression
B-cells in cancer immunology: for or against cancer growth?
The roles of CD4+ T-cells in tumor immunity
Regulatory T-cells and Th cells in tumor microenvironment
T-cell metabolism and its dysfunction induced by cancer
The role of exhaustion in tumor-induced T-cell dysfunction in cancer
The role of NK cells in cancer
Role of plasmacytoid dendritic cells in cancer
The CD95/CD95L signaling pathway: a role in carcinogenesis
MHC class I molecules and cancer progression: lessons learned from preclinical mouse models
Role of cytokines in tumor immunity and immune tolerance to cancer
Role of chemokines and chemokine receptors in cancer
Role of the inflammasome in cancer
Cancer immunoediting: immunosurveillance, immune equilibrium, and immune escape
Apoptosis and cancer
Endoplasmic reticulum stress and autophagy in cancer
Prognostic value of innate and adaptive immunity in cancers
Immunogenetics of cancer
Epigenetics and MicroRNAs in cancer
The role of DNA methylation in cancer
Immunosenescence, oxidative stress, and cancers
Nutrition, immunity, and cancers
Inborn errors of immunity and cancers
Allergies and cancers
Envisioning the application of systems biology in cancer immunology
Principles of immunological diagnostic tests for cancers
Immunohistochemistry of cancers
Fluorescent in situ hybridization: methods and application in cancer diagnosis
Cancer molecular and functional imaging
Cancer imaging with radiolabeled monoclonal antibodies
Flow cytometry in cancer immunotherapy: applications, quality assurance, and future.