BookJaime M. Monti, S.R. Pandi-Perumal, Eric Murillo-Rodríguez, editors.
Summary: Research on cannabis and sleep is emerging with promising results. This book offers current and comprehensive knowledge on cannabinoid research results in connection with sleep. The volume covers aspects of the hemp plant Cannabis sativa, the pharmacology of cannabinoids, neurobiology and pharmacology of sleep and wakefulness, and the benefits and side effects of cannabis on the central nervous system. It further discusses the putative therapeutical properties of cannabinoids and endocannabinoids and their potential for the treatment of sleep disorders such as insomnia, obstructive sleep apnea, REM sleep behavior disorder, and restless legs syndrome. The book is written by medical and scientific experts in this field and intended for researchers from a range of disciplines such as biomedicine, biology, neurosciences, clinical medicine, neurology, and pharmacology.
Contents:
Constituents of Cannabis Sativa
Synthetic and Natural Derivatives of Cannabidiol
Clinical Pharmacokinetics of Cannabinoids and Potential Drug-Drug Interactions
Cannabinoid Receptors and Ligands: Lessions from CNS Disorders and the Quest for Novel Treatment Venues
Sleep-Wake Neurobiology
Cannabinoids and Sleep/Wake Control
Effects of Cannabinoid Agonists and Antagonists on Sleep in Laboratory Animals
Modulation of Noradrenergic and Serotonergic Systems by Cannabinoids: Electrophysiological, Neurochemical and Behavioral Evidence
Natural Cannabinoids as Templates for Sleep Disturbances Treatment
The Effect of Cannabinoids on the Brain´s Circadian Clock
Effects of Cannabis Consumption on Sleep
Addiction and Sleep Disorders
Cannabis for Restless Legs Syndrome.