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  • Book
    Yuman Fong, T. Clark Gamblin, Ernest S. Han, Byrne Lee, Jonathan S. Zager, editors.
    Summary: This book is a state-of-the-art overview of cancer regional therapy (CRT) for the surgeons and interventional radiologists active in CRT development and research. The goals of this book are 1) to review the theory and practice of cancer regional therapies including pharmacology, devices, techniques, and workflow, 2) illustrate the most common procedures performed in the interventional and operating rooms, and 3) discuss data supporting use of CRT. This is meant to be a definitive text on the theory and practice of CRT. It begins with a summary of the history, technical principles that underlie regional therapy. The following parts discuss current data and practice in peritoneal, liver, limb, pleural and other sites. Included in the practice are considerations of workflow and financial issues revolving around CRT. Novel techniques and therapies under investigation are presented to inform the direction of the field. Cancer Regional Therapy summarizes the history, current technology, common procedures, and future prospects in this field and includes procedures from many surgical and interventional radiologic disciplines.

    Contents:
    The Basis of Regional Therapy, Pharmacology, Hyperthermia, and Drug Resistance
    Novel Biological Therapies with Direct Application to the Peritoneal Cavity
    Y-90 Radiomicrosphere Therapy: Principles and Clinical Use in Colorectal Cancer Liver Metastases
    Principles of Percutaneous Ablation in the Liver
    Regional Gene Therapy for Cancer
    Historical Perspective for Regional Peritoneal Therapy: HIPEC, EPIC and Port-based Therapy
    Rationale Behind HIPEC/Molecular and Genetic Considerations in HIPEC
    Data for HIPEC for Pseudomyxoma Peritonei/Tumors of the Appendix
    Data for HIPEC in Colorectal Cancer (T4 Lesions and Metastases)
    Role of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the Treatment of Peritoneal Metastasis of Gastric Cancer
    Regional Therapy for the Treatment of Ovarian Cancer: HIPEC and Intraperitoneal Chemotherapy
    Mesothelioma and Miscellaneous Disease Processes
    Anesthetic Considerations for Regional Therapies
    Post-Operative Management of Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
    Complications of Cytoreductive Surgery and HIPEC
    Liver Resection and HIPEC
    Peritoneal Perfusion Techniques
    Operative Pearls for Cytoreduction of the Difficult Abdomen and Pelvis
    Novel Techniques and the Future of HIPEC (Immunotherapy, Viral Therapy)
    Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC).
    Digital Access Springer 2020