BookFrancis J. Hornicek, editor.
Summary: Chondrosarcoma, a rare cancer that develops from cartilage cells, occurs mainly in the bones but can also appear in the soft tissue of the pelvis, hip and shoulder. Unfortunately, these cancers are highly resistant to both chemotherapy and radiation, and no successful adjuvant therapies currently exist. As such, surgical treatment and resection remain the mainstays of management for patients with these tumors. This concise text is a comprehensive presentation of the current knowledge regarding the development, diagnosis and management of chondrosarcomas. Part I discusses pathology, molecular biology and imaging features of chondrosarcomas. The different types of skeletal and extraskeletal tumors are presented in detail in part II, including conventional and secondary tumors. Management approaches are outlined and described in part III - limb salvage surgery is the most common, and although less effective, radiation and chemotherapy are indicated in certain cases. Part IV examines the future of chondrosarcoma management and development of novel adjuvant therapies, as well as the relationship of this disease to similar types (e.g., chordoma). Bringing together the most up-to-date information on this rare cancer, Chondrosarcoma will be a valuable resource for orthopedic oncologists, researchers and all medical professionals treating these challenging tumors.
Contents:
Part I. Biology of Chondrosarcoma
Pathology of Chondrosarcoma
Advances in the Molecular Biology of Chondrosarcoma
Imaging Features of Chondrosarcoma
Part II. Skeletal and Extraskeletal Chondrosarcoma
Chondrosarcomas: Conventional and Secondary
Primary Soft Tissue Chondrosarcoma
Part III. Management of Chondrosarcoma
Chondrosarcoma of the Axial Skeleton
Chondrosarcoma of the Appendicular Skeleton
Chondrosarcoma of the Hand
Chondrosarcoma of the Clavicle
Radiation Therapy for Chondrosarcoma
Systemic Therapy for Chondrosarcoma
Vascular Issues in Complex Surgical Resection of Chondrosarcoma
Part IV. The Future of Chondrosarcoma Research and Treatment
The Future of Chondrosarcoma Research and Treatment.