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  • Book
    Mary Hesdorffer, Gleneara E. Bates-Pappas, editors.
    Summary: This book encompasses all areas for mesothelioma care, treatment, and research. Using nurses, social workers, surgeons, oncologist, radiologist and pain specialist to give the reader a comprehensive overview of mesothelioma treatment. Indeed, mesothelioma is a cancer that mainly affects the pleura and peritoneum, usually caused by exposure to asbestos. The number of individuals diagnosed with mesothelioma is increasing world-wide, particularly in developing countries where the use of asbestos remains uncontrolled. In spite of advances in chemotherapy, radiotherapy, and surgical approaches, mesothelioma remains resistant to treatment. According to the International Mesothelioma Interest group, overall survival has not improved; median survival times vary from one month to eighteen months. A small number of patients remain asymptomatic or with minimal symptoms for extended periods, and fewer live three years or more. Mesothelioma is often associated with difficult, intractable symptoms, particularly pain and difficulty breathing. Especially poor prognoses have been reported for those diagnosed with sarcomatoid rather than epithelioid histology, or with advanced disease, poor performance status, or pain and loss of appetite. Despite substantial progress of the last two decades improving the quality of life of patients with cancer, many mesothelioma patients still experience physical, psychological, social, and financial burdens. The development of multimodality treatment and mesothelioma centers has given renewed hope to patients. This book serves as a unique tool for medical professional while providing care for mesothelioma patients.

    Intro; Foreword; Contents; About the Editors; Part I: Mesothelioma Treatment;
    1: History of Pleural Surgical Treatment; 1 Macroscopic Complete Resection (MCR) Surgery; 1.1 Pleurectomy and Decortication; 1.2 Extrapleural Pneumonectomy; 2 Palliative Surgical Procedures; 2.1 Parietal Pleurectomy; 2.2 Pleurodesis/PleurX Catheter; 3 Outcomes; 4 Multimodality Treatment; References;
    2: History Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Peritoneal Metastasis and Evolution and Contemporary Application in Peritoneal Mesothelioma; 1 History of Cytoreductive Surgery 2 Mesothelioma Patient Selection for CRS/HIPEC3 Factors in Outcome and Survival in MPM and CRS/HIPEC; 4 Emerging Therapies and Future Direction; References;
    3: Cytoreductive Surgery and Intraperitoneal Chemotherapy for Treatment of Malignant Peritoneal Mesothelioma; 1 The Natural History of Malignant Peritoneal Mesothelioma; 2 Intraperitoneal Chemotherapy Alone for Malignant Peritoneal Mesothelioma; 3 Results of Treatment Combining Cytoreductive Surgery with Intraperitoneal Chemotherapy; 4 Current Standard of Care for Treatment of MPM 5 Recent Results with Cytoreductive Surgery, HIPEC, and NIPEC6 Evolution of Surgical Treatments; 7 Rationale for Peritonectomy Procedures and Visceral Resections; 8 Locations of Malignant Peritoneal Mesothelioma; 9 Electroevaporative Surgery; 10 Abdominal Exposure; 11 Total Anterior Parietal Peritonectomy; 12 Left Subphrenic Peritonectomy; 13 Greater Omentectomy and Possible Splenectomy; 14 Right Subphrenic Peritonectomy; 15 Stripping of Tumor from Glisson's Capsule; 16 Lesser Omentectomy and Cholecystectomy with Stripping of the Hepatoduodenal Ligament 17 Circumferential Resection of the Hepatogastric Ligament and Lesser Omental Fat by Digital Dissection18 Stripping of the Floor of the Omental Bursa; 19 Complete Pelvic Peritonectomy; 20 Resection of Rectosigmoid Colon and Cul-de-sac of Douglas; 21 Vaginal Closure and Low Colorectal Anastomosis; 22 Optimization of Cytoreduction of Small Bowel and Its Mesentery; 22.1 Five Types of Small Bowel Involvement by Cancer; 22.2 Techniques Used in Cytoreduction of the Small Bowel; 23 Follow-Up; References;
    4: Radiation Therapy 1 Integration of Radiation Therapy into Multimodality Management Regimen2 Radiation Therapy; 2.1 Radiation Therapy in the Setting of EPP; 2.2 Adjuvant Radiation Therapy After P/D; 2.3 Other Indications for Radiation Therapy; References; Part II: Therapeutic Treatments: Chemotherapy, Biotherapy, and Immunotherapy;
    5: Chemotherapy and Standard Treatment Options; 1 Background; 2 Chemotherapy Clinical Trials Nursing and Mesothelioma; 3 Chemotherapy Symptoms and Tolerability; 4 The Future of Chemotherapeutic Treatment; References
    Digital Access Springer 2019