Bookedited by William Clarke, Amitava Dasgupta.
Summary: This guide surveys critical issues in therapeutic drug monitoring for non-toxicologists who want to gain greater insight into the unique requirements of special populations and learn how to avoid drug toxicity within a narrow therapeutic window.
Contents:
Overview of therapeutic drug monitoring
Immunoassays and issues with interference in therapeutic drug monitoring
Application of chromatography combined with mass spectrometry in therapeutic drug monitoring
Monitoring free drug concentration : clinical usefulness and analytical challenges
Therapeutic drug monitoring of newer antiepileptic drugs
Therapeutic drug monitoring of antiretrovirals
Therapeutic drug monitoring in infants and children
Therapeutic drug monitoring in pregnancy
Therapeutic drug monitoring in older people
Therapeutic drug monitoring in obese patients
Special issues in therapeutic drug monitoring in patients with uremia, liver disease, and in critically ill patients
Issues of pharmacogenomics in monitoring warfarin therapy
Alternative sampling strategies for therapeutic drug monitoring
Integrating therapeutic drug monitoring in the health care environment : therapeutic drug monitoring and pharmacists.