BookMaciej Banach, editor.
Summary: This book is the first comprehensive approach on COVID-19 cardiac complications, both during the acute phase as well as in the long-COVID period. It provides an up-to-date and highly illustrated summary of the biology of SARS-CoV-2, the course of COVID-19, risk factors that worsen the disease in COVID-19 patients, clinical features of COVID-19 patients, COVID-19 cardiological complications, treatment, and prevention methods, and long-term cardiological aspects of COVID-19. Chapters provide the reader with a contemporary perspective on the emerging links between COVID-19 and cardiovascular disease. In addition, this volume discusses the clinical implications and therapeutic goals in patients with COVID-19 and cardiac complications, as well as possible therapeutic options. It also offers clear recommendations on how to manage (both non- and pharmacologically) to avoid the increased number of COVID-19 related deaths due to CVD and its risk factors. Cardiovascular Complications of COVID-19 will be the primary resource for physicians, residents, fellows, and nursed and medical students in the fields of cardiology and COVID-19/infectious diseases as well as healthcare providers that initiate preventive activities and dedicated programs.
Contents:
Intro
Foreword
Preface
Acknowledgments
Contents
Part I: General Part
Chapter 1: Biology of SARS-CoV-2 Coronavirus
Origin, Structure, and Variants
Introduction
Method of Search
The SARS-CoV-2 Biology
The SARS-CoV-2 Origins
HCoV-229E
HCoV-OC43
SARS-CoV
HCoV-NL63
HCoV-HKU1
MERS-CoV
SARS-CoV-2
The SARS-CoV-2 Structure
SARS-CoV-2 Variants
Conclusion
References
Chapter 2: COVID-19 Epidemiology and Differences in Incidence and Mortality Between Countries
Origins
Asian Countries
COVID-19 in the United States of America Canada
Mexico
Peru
Brazil
Colombia
Europe
Russia
Ukraine
Italy
Poland
South Africa
Antarctica
References
Chapter 3: Clinical Symptoms and Course of COVID-19
SARS-CoV-2 Transmission
Virus Replication
Immunological Responses and Cytokine Storm (CS)
Virus Variants and Associated Evolution in the Clinical Course
Clinical Stages of COVID-19 [21]
Mild and Asymptomatic Stage
Symptomatic Stage
Severe Disease
Acute Respiratory Distress Syndrome/Critical Stage
Clinical Symptoms of COVID-19 General Symptoms in the Early, Asymptomatic and Mild Infection
Respiratory Manifestations
Extra-Respiratory Manifestations
Hematologic Abnormalities
Prothrombotic Events
Cardiovascular Involvement
Neurological and Neuropsychiatric Manifestations
Kidney Involvement
Gastrointestinal and Hepatic Involvement
Skin Associated COVID-19 Symptoms
COVID-19 in Children
Long COVID-19
Conclusions
References
Chapter 4: Risk Factors of Developing COVID-19 and its Severe Course
COVID-19 and Related Cardiovascular Risk Factors
Age
Sex
Smoking
Diabetes Obesity
Hypertension
Dyslipidemia
Chronic Kidney Disease
Additional Markers of Increased CV Disease Risk in COVID-19
References
Chapter 5: Prognosis in COVID-19 Patients: Statistics, Risk Factors
Introduction
Demographic Features
Age and Sex
Ethnicity
Clinical Symptoms
Comorbidities and the Course of COVID-19
Hypertension
Diabetes Mellitus
Obesity
Chronic Obstructive Pulmonary Disease (COPD)
Chronic Kidney Disease
Cancer
Special Conditions and Populations of Patients and the COVID-19 Course
Smoking
Pregnancy
Children Selected Laboratory Parameters Values and the COVID-19 Course
Leukocyte Counts
Lymphocyte Counts
Neutrophil Counts
Platelet Counts
C-Reactive Protein (CRP)
Procalcitonin (PCT)
Lactate Dehydrogenase (LDH)
Interleukin 6 (IL-6)
D-Dimer
Ferritin
Albumin
Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT)
Cardiac Troponin
Complications
Reinfection
Conclusions and Take-Home Message
References
Part II: Cardiovascular Complications of the Acute Phase of COVID-19