BookSamer N. Narouze, editor.
Summary: This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions. Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain. Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research. Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.
Contents:
History of Cannabis
Cannabis Regulations
The demand for medical cannabis education
Pain physicians and cannabis: attitudes and beliefs
Cannabis Terminology
THE ENDOCANNABINOID SYSTEM
The CB1 Receptors
The CB2 Receptors
Endocannabinoids: Anandamide and 2-AG
Phytocannabinoids:Tetrahydrocannabinol (THC)
Phytocannabinoids: Cannabidiol (CBD)
Other Phytocannabinoids
Cannabinoids Drug interaction
Dronabinol (Marinol)
Nabilone (Cesamet)
Cannabidiol (Epidiolex)
Nabiximols (Sativex)
Medical Cannabis Strains
The model of a specialized cannabis clinic
Barriers for the prescription of cannabis-based medicines
Practical recommendations for the use of medical cannabis
Medical Cannabis Dosing and Titration
Patient safety considerations
Cannabinoids and Pain: Mechanisms of action
Cannabinoids and Pain: Clinical Evidence
Cannabinoids and Cancer Pain
Cannabinoids as a substitute for opioids: Basic science and Clinical evidence
Cannabiinoids as a substitute for opioids: Suggested algorithm
Perioperative management of patients on cannabinoids
The Colorado Experience
Product Safety and Quality control
Cannabis and brain development
Cannabis and mental health risks
Cannabis and adolescents
Cannabis and child development during and after pregnancy
Cannabis impairment and Adverse events
Vaping hazards
Cannabis Use Disorder
Cannabis withdrawal
Future research.