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  • Book
    Samer N. Narouze, editor.
    Summary: This book presents a well-balanced view of the potential medical use of cannabinoids in pain. It comprehensively covers the current challenges with medical cannabis utilization and provides recommendations for research and future directions. Organized into nine sections, the book begins with an introduction to medical cannabis, including its history, regulations, and the general attitudes of pain physicians on cannabis. Section two explores the biological effects of marijuana via the endocannabinoid system and its complex structure of receptors and enzymes. Sections three, four, and five then delve further into pharmacology and the mechanisms of action applicable to cannabinoids in managing pain. Timely and socially conscious, section six examines the benefits of substituting opioids with cannabinoids for preoperative management. Echoing the book's well-rounded content, sections seven and eight consider the challenges with medical cannabis, including safety and quality control, brain development risks, vaping hazards, and withdrawal. The book then closes with a look at the future of cannabis in medical research. Thoroughly and equitably composed, Cannabinoids and Pain is an invaluable resource for primary care physicians, pain and palliative care physicians, and oncologists.

    Contents:
    History of Cannabis
    Cannabis Regulations
    The demand for medical cannabis education
    Pain physicians and cannabis: attitudes and beliefs
    Cannabis Terminology
    THE ENDOCANNABINOID SYSTEM
    The CB1 Receptors
    The CB2 Receptors
    Endocannabinoids: Anandamide and 2-AG
    Phytocannabinoids:Tetrahydrocannabinol (THC)
    Phytocannabinoids: Cannabidiol (CBD)
    Other Phytocannabinoids
    Cannabinoids Drug interaction
    Dronabinol (Marinol)
    Nabilone (Cesamet)
    Cannabidiol (Epidiolex)
    Nabiximols (Sativex)
    Medical Cannabis Strains
    The model of a specialized cannabis clinic
    Barriers for the prescription of cannabis-based medicines
    Practical recommendations for the use of medical cannabis
    Medical Cannabis Dosing and Titration
    Patient safety considerations
    Cannabinoids and Pain: Mechanisms of action
    Cannabinoids and Pain: Clinical Evidence
    Cannabinoids and Cancer Pain
    Cannabinoids as a substitute for opioids: Basic science and Clinical evidence
    Cannabiinoids as a substitute for opioids: Suggested algorithm
    Perioperative management of patients on cannabinoids
    The Colorado Experience
    Product Safety and Quality control
    Cannabis and brain development
    Cannabis and mental health risks
    Cannabis and adolescents
    Cannabis and child development during and after pregnancy
    Cannabis impairment and Adverse events
    Vaping hazards
    Cannabis Use Disorder
    Cannabis withdrawal
    Future research.
    Digital Access Springer 2021