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  • Book
    Omar M.E. Abdel-Salam, editor.
    Summary: This volume provides an up-to-date account of the achievements pertaining to the application of capsaicin and capsaicin-like molecules in the therapy of various human ailments such as pain, non-allergic rhinitis, obesity, tumors, and gastrointestinal, dermatologic, and urologic disorders. It discusses the basic functions of the capsaicin receptor (TRPV1), its mechanisms of action, and its role in physiological and pathological processes. The text focuses on the most recent progress in the use of capsaicin and capsaicin-like molecules as a therapeutic agent and highlights potential pharmaceutical implications of further TRPV1 research. The chapters are written by noted experts in their fields of endeavor. This book offers both clinicians and researchers valuable resource and reference material on the subject that will stimulate future research.

    Contents:
    Capsaicin and Sensory Neurones: a Historical Perspective
    Pharmacology of the Capsaicin Receptor, Transient Receptor Potential Vanilloid Type 1 Ion Channel
    TRPV1 in the Central Nervous System: Synaptic Plasticity, Function and Pharmacological Implications
    Topical Capsaicin Formulations in the Management of Neuropathic Pain
    Capsaicin-Based Therapies for Pain Control
    Intranasal Capsaicin in Management of Non-allergic (Vasomotor) Rhinitis
    Capsaicin as an Anti-obesity Drug
    The Potential Antitumour Effects of Capsaicin
    Capsaicin as New Orally Applicable Gastroprotective and Therapeutic Drug Alone or in Combination with Non-Steroidal Anti-inflammatory Drugs in Human Healthy Subjects and in Patients
    Calcitonin Gene-Related Peptide as Target of Capsaicin Receptor in the Gut
    Capsaicin for Osteoarthritis Pain
    The Role of Capsaicin in Dermatology
    Use of Vanilloids in Urologic Disorders.
    Digital Access Springer 2014