BookAlessandro Zanasi, Giovanni A. Fontana, Donatella Mutolo, editors.
Summary: This book provides an updated and comprehensive overview of cough, while opening new perspectives for their treatment and management. It enables readers to not only discover new physiologic features and mechanisms but also to gain an in-depth understanding of the diagnostic workup of cough, still one of the most frequent and challenging symptoms in daily medical practice. The book also provides insights into coughs features and pathogenesis, as well as into pharmacologic and non-pharmacologic treatments. The most frequent causes of chronic cough (asthma, postnasal drip, gastroesophageal reflux and chronic hypersensitivity syndrome) and different types of pediatric cough are also explored. Coughing is a common symptom, occurring in many clinical settings, and as such the book appeals a broad readership, including pulmonologists specialized in cough, general practitioners, internists, pediatricians and otorhinolaryngologists.
Contents:
Intro
Preface
Contents
Part I: Cough Sensorymotor Mechanisms
1: Physiology of the Cough Reflex: Sensory and Mechanical Features
1.1 General Features
1.2 Cough-Related Afferents
1.2.1 Tracheobronchial Tree
1.2.2 Larynx
1.2.3 Bronchoconstriction and Cough
1.3 Bronchopulmonary Sympathetic Afferents
1.4 Respiratory Muscles
1.5 Phases of Cough and Expiratory Flow
1.5.1 Inspiratory or Preparatory Phase
1.5.2 Postinspiratory or Compressive Phase
1.5.3 Expiratory or Expulsive Phase
1.5.4 Cessation Phase
References 2: Sensory Pathways and Neural Modulation of Cough
2.1 Cough Afferents
2.2 Cough Receptors
2.3 Cough C-Fibers
2.4 Modulation
2.5 Vagus Nerve Conductivity
2.6 Reflex Modulation of Cough
2.7 Interaction of Motor Responses
References
3: Brainstem Structures Involved in the Generation of Reflex Cough
3.1 Introductory Remarks
3.2 Central Terminations of Cough-Related Afferents
3.3 Brainstem Respiratory Network
3.4 Role of Brainstem Structures in the Generation of the Cough Reflex
3.5 Additional Neural Mechanisms Controlling or Modulating the Cough Reflex 3.6 Insights into the Brainstem Mechanisms by the Action of Antitussive or Protussive Drugs
3.6.1 Caudal Nucleus Tractus Solitarii
3.6.2 Caudal Ventral Respiratory Group (Nucleus Retroambigualis)
3.7 Concluding Remarks
References
4: The Cough Motor Pattern
References
Part II: Clinical Assessment of Cough
5: Acute and Chronic Cough
5.1 General Aspects
5.2 Acute Cough
5.2.1 Common Causes of Acute Cough
5.2.2 Less Common Causes of Acute Cough
5.2.2.1 Heart Failure
5.2.2.2 Pneumonia
5.2.2.3 Pulmonary Embolism
5.2.2.4 Aspiration Pneumonia 5.3 Chronic Cough and the Cough Hypersensitivity Syndrome
5.3.1 Common Causes of Chronic Cough
5.3.2 Less Common Causes of Chronic Cough
5.3.2.1 Chronic Bronchitis
5.3.2.2 Bronchiectasis
5.3.2.3 Post-infectious Cough
5.3.2.4 Bronchogenic Carcinoma
5.3.2.5 Coughs Due to Antihypertensive Angiotensin-Converting-Enzyme Inhibitor Drugs
5.3.2.6 Idiopathic Pulmonary Fibrosis
5.3.2.7 Psychogenic or Habitual Cough
References
6: Chronic Cough and Upper Airway Syndrome
6.1 Definition and Pathogenesis
6.2 Prevalence
6.3 Diagnosis
6.4 Allergic Rhinitis 6.5 Non-allergic Perennial Rhinitis
6.6 Vasomotor Rhinitis
6.7 Drug-Induced Rhinitis
6.8 Rhinitis During Pregnancy
6.9 Postinfectious Rhinitis
6.10 Chronic Sinusitis
6.11 Therapy
References
7: Chronic Cough During Bronchial Asthma
7.1 General Aspects
7.2 Prevalence
7.3 Characteristics of Asthmatic Inflammation
7.4 Relationship Between Coughing and Bronchial Inflammation
7.5 Relationships Between Coughing and Bronchoconstriction
7.6 Medical History and Objective Examination
7.7 Instrumental Findings
7.8 Therapy
References
8: Chronic Cough During Gastro-oesophageal Reflux.