Books

Summary: Point and click your way to performing statistics! Many people are intimidated by learning statistics, but A Gentle Introduction to Statistics Using SAS Studio in the Cloud is here to help. Whether you need to perform statistical analysis for a project or, perhaps, for a course in education, psychology, sociology, economics, or any other field that requires basic statistical skills, this book teaches the fundamentals of statistics, from designing your experiment through calculating logistic regressions. Serving as an introduction to many common statistical tests and principles, it explains concepts in an intuitive way with little math and very few formulas. The book is full of examples demonstrating the use of SAS Studio's easy point-and-click interface accessed with SAS OnDemand for Academics, an online delivery platform for teaching and learning statistical analysis that provides free access to SAS software via the cloud. Topics included in this book are: How to access SAS OnDemand for Academics Descriptive statistics One-sample tests T tests (for independent or paired samples) One-way analysis of variance (ANOVA) N-way ANOVA Correlation analysis Simple and multiple linear regression Binary logistic regression Categorical data, including two-way tables and chi-square Power and sample size calculations Questions are provided to test your knowledge and practice your skills.

Contents:
Descriptive and inferential statistics
Study designs
What is SAS OnDemand for academics?
SAS Studio tasks
Importing data into SAS
Descriptive statistics : univariate analysis
One-sample tests
Two-sample tests
Comparing more than two means (ANOVA)
N-Way ANOVA
Correlation
Simple and multiple regression
Binary logistic regression
Analyzing categorical data
Computing power and sample size
Solutions to the Odd-Numbered exercises

Contents:
Caring for critically ill children and their families
Pulmonary system
Cardiovascular system
Neurologic system
Renal system
Endocrine system
Gastrointestinal system
Hematology and immunology systems
Multisystem issues
Professional issues: quality, safety, work environment, and wellness.

Summary: "Succinct, complete guidance on how to safely and competently care for adult, critically ill patients and their families written by top clinical experts. Endorsed by the American Association of Critical-Care Nurses (AACN), this acclaimed textbook sets the standard for critical care nursing education. Recognizing the learner's need to assimilate foundational knowledge before attempting to master more complex critical care nursing concepts, the book features a practical building-block organization that starts with the basics and logically progresses to advanced topics. Bolstered by helpful tables and essential content cases, AACN Essentials of Critical Care Nursing is an essential tool for clinicians at the point of care, and those preparing for CCRN® certification in critical care nursing. AACN Essentials of Critical Care Nursing, Fourth Edition is presented in four sections: The Essentials presents core information that new clinicians must understand to provide safe, competent nursing care to all critically ill patients, regardless of their underlying medical diagnoses. Pathologic Conditions covers pathologic conditions and management strategies commonly encountered among adult critical care patients. Advanced Concepts in Caring for the Critically Ill Patient moves beyond the essentials and includes information about specific pathologic conditions that require specialized critical care management. Key Reference Information features normal laboratory and diagnostic values, troubleshooting guides for hemodynamic monitoring, summary tables of critical care drugs, and cardiac rhythms and treatment guides. Learning aids include Knowledge Competencies that can be used to gauge progress, Principles of Management to summarize key concepts and "Essential Content" case studies with questions and answers to further reinforce the learners' knowledge"-- Provided by publisher.

Contents:
Section I: The essentials. Assessment of critically ill patients and their families / Mary Fran Tracy
Planning care for critically ill patients and their families / Mary Fran Tracy
Interpretation and management of basic cardiac rhythm / Carol Jacobson
Hemodynamic monitoring / Leanna R. Miller
Airway and ventilatory management / Robert E. St. John and Maureen A. Seckel
Pain, sedation, and neuromuscular blockade management / Yvonne D'Arcy and Sara Knippa
Pharmacology / Earnest Alexander
Ethical and legal considerations / Sarah A. Delgado. Section II: Pathologic conditions. Cardiovascular system / Barbara Leeper
Respiratory system / Maureen A. Seckel
Multisystem problems / Julie Grishaw
Neurologic system / John C. Bazil and Daiwai Olson
Hematologic and immune systems / Diane K. Dressler
Gastrointestinal system / Beth Quatrara
Renal system / Jie Chen
Endocrine system / Mary E. Lough
Trauma / Alan C. Wolfe Jr. and Benjamin W. Hughes. Section III: Advanced concepts. Advanced ECG concepts / Carol Jacobson
Advanced cardiovascular concepts / Barbara Leeper
Advanced respiratory concepts: modes of ventilation / John J. Gallagher
Advanced neurologic concepts / John C. Bazil and Daiwai Olson. Section IV: Key reference information. Normal laboratory reference values / Suzanne M. Burns and Sarah A. Delgado
Pharmacology tables / Earnest Alexander
Hemodynamic monitoring troubleshooting guide / Leanna R. Miller
Cardiac rhythms, ECG characteristics, and treatment guide / Carol Jacobson.

Summary: "Succinct, complete guidance on how to safely and competently care for adult progressive care patients and their families written by top clinical experts Endorsed by the American Association of Critical-Care Nurses (AACN), this acclaimed textbook sets the standard for progressive care nursing education. Recognizing the learner's need to assimilate foundational knowledge before attempting to master more complex progressive care nursing concepts, the book features a practical building-block organization that starts with the basics and logically moves on to advanced topics. Bolstered by helpful tables and Essential Content cases, AACN Essentials of Progressive Care Nursing, Fourth Edition is an essential tool for clinicians at the point of care, and those preparing for PCCN® certification in progressive care nursing. AACN Essentials of Progressive Care Nursing is divided into four sections: The Essentials presents essential information that clinicians must understand to provide safe, competent nursing care to progressive care patients, regardless of their underlying medical diagnoses. Pathologic Conditions covers pathologic conditions and management strategies commonly encountered among adult, progressive care patients. Advanced Concepts in Caring for the Progressive Care Patient presents advanced progressive care concepts or pathologic conditions that are less common or require more specialized management. Key Reference Information features normal laboratory and diagnostic values; pharmacology tables; and summary tables of cardiac rhythms, ECG characteristics, and treatment guides. Learning aids include Knowledge Competencies to gauge progress, Principles of Management to summarize key concepts, and "Essential Content" case studies with questions and answers to further reinforce the learners' knowledge"-- Provided by publisher

Contents:
Assessment of progressive care patients and their families
Planning care for progressive care patients and their families
Interpretation and management of basic cardiac rhythms
Hemodynamic monitoring
Airway and ventilatory management
Pain and sedation management
Pharmacology
Ethical and legal considerations
Cardiovascular system
Respiratory system
Multisystem problems
Neurological system
Hematologic and immune systems
Gastrointestinal system
Renal system
Endocrine system
Trauma
Advanced ECG concepts
Advanced cardiovascular concepts
Advanced neurologic concepts
Normal laboratory reference values
Pharmacology tables
Cardiac rhythms, ECG characteristics, and treatment guide.

Summary: "Edited by the American Association of Critical-Care Nurses and written by more than 100 critical care experts under the direction of Karen L. Johnson, PhD, RN, FAAN, this definitive reference represents the gold standard of care for procedures performed in progressive and critical care settings. It guides you through procedures common to the adult critical care environment, including those performed by advanced practice nurses, in an illustrated, step-by-step format. This edition — now in in full color — features new procedures, new and updated illustrations, and updated content throughout, reflecting the latest evidence-based guidelines and national and international protocols. Quick-reference tabs make it easier than ever to locate content quickly. This new edition integrates key AACN initiatives, such as Practice Alerts, and coordinates closely with the AACN Core Curriculum for Progressive and Critical Care Nursing, 8th Edition. Chapter-specific quick-links employ QR codes for instant access to high-quality online references."--Provided by publisher.

Summary: "AACN Tele-critical Care Nursing Practice: An Expert Consensus Statement Supporting Acute, Progressive and Critical Care 2022 provides hospitals, leaders, and nurses with recommendations, clinical vignettes, and a framework to implement, evaluate, and improve their evolving practice. This new statement explores the many practice changes and keeps pace with expanding applications in this area of telemedicine, and supports the terminology shift to tele-critical care. It identifies essential tele-critical care elements, reflects current evidence, and delivers a fresh perspective to this fast-growing area of healthcare. The 2021 tele-critical care nursing expert consensus statement task force brought together tele-critical care nursing leaders from diverse backgrounds to share best practices, evidence, and lessons learned. The expertise and dynamic, front-line viewpoint of these experts has resulted in a comprehensive, patient-centric update. Their experience delivering both on-site direct care and remote care was instrumental in developing clinical vignettes and outlining key tele-critical care nursing interventions. The vignettes are real-world examples of how each key recommendation is implemented to provide continuity of care; demonstrate the value of tele-critical care nursing for a strong return on investment; identify high-risk patients; and decrease mortality rates by leveraging clinician expertise and technology, and partnering with on-site nurses to provide expert evidence-based care"-- Publisher's description.

Contents:
Introduction
Purpose --Conceptual frameworks
AACN tele-critical care nursing practice model
AACN tele-critical care nursing practice recommendations
Conclusions.

Summary: Vol. 1 Contains standards for equipment, decontamination of medica by steam, ethylene oxide, gamma radiation, and electron beam radiation. -- Vol. 2 Contains standards for biomedical equipment. -- Vol. 3 Contains all documents developed under the auspices of the Renal Disease and Detoxification Committee and Hemodialyzer Reuse Submittee.

Contents:
v. 1. Sterilization
v. 2. Biomedical equipment
v. 3. Dialysis.

Summary: "AAOS Comprehensive Orthopaedic Review, 4th Edition is a comprehensive three-volume set that covers the spectrum of orthopaedic specialties. With over 300 physician contributors, content is presented in a concise outline format, organized by specialty, and offers a quick bulleted review of concepts. Chapters feature color images, illustrations, tables, and charts to reinforce material"-- Provided by publisher.

Summary: "AAOS Comprehensive Orthopaedic Review, 3rd edition offers sweeping coverage of the core of orthopaedic knowledge that spans the spectrum of the orthopaedic specialties. This convenient, comprehensive and user-friendly text combines the specific information you need to prepare for your examination. Study to prepare for your Board Exam! This 3-volume study set is designed to prepare orthopaedic residents for the Orthopaedic In Training Exam (OITE), and the American Board of Orthopaedic Surgery (ABOS) Board Certification examination. Dr. Lieberman and his editorial team of Board-certified orthopaedic surgeons edited and present this thorough text in a concise outline format, giving you ready access to the important facts as a quick bulleted review of the concepts you need to know. Study to retain knowledge! With relevant content developed and updated by over 400 physician contributors and editors, this third edition reinforces what you've learned on your daily rounds and skills labs. Organized by specialty, each of the 149 chapters is loaded with color images, illustrations, tables, and charts to support the material and help you retain the information. Study to achieve proficiency! Pinpoint areas for further study by self-testing with nearly 500 multiple-choice companion study questions. Each question includes the preferred response with additional discussion and explanation of the topics. This set is your ideal exam study prep program"--Provided by publisher.

Summary: The AAP Healthy Development and Well-Child Support Chart provides pediatric health professionals with a quick and easy-to-use reference on some of the most important areas covered in the pediatric well-child visit.

Contents:
Intro
What Children Need to Thrive
Promoting Early Brain and Child Development
Developmental Milestones: 1-12 Months
Developmental Milestones: 13-33 Months
Developmental Milestones: 3-6 Years
Social-Emotional Milestones
Social-Emotional Development
Adolescent Development
Behavioral Concerns
Mental Health
Gender Care
Obesity Care
Physical Activity
Sleep
Toxic Stress and Resilience

Summary: This convenient point-of-care resource provides practitioners with an evidence-based quick reference guide for evaluating and treating overweight and obesity in the clinical setting.

Contents:
Front Matter
1. AAP Key Action Statements
2. AAP Consensus Recommendations
3. Algorithm for Pediatric Overweight and Obesity
4. Evaluation
5. Stigma and Communication
6. Clinical Flow: Assessment and Evaluation
7. Risk
8. Physical Examination Findings
9. Commonly Prescribed Medications and Weight Gain
10. Conditions That Occur With Obesity
11. Treatment
12. Treatment in the Primary Care Office
13. Intensive Health Behavior and Lifestyle Treatment
14. My Goal Sheets
15. Operationalizing Care
16. Welcoming Office
17. Capacity Considerations
18. Coding for Overweight and Obesity
19. 5210 Healthy Habits Questionnaire (Ages 2-9)
20. 5210 Healthy Habits Questionnaire (Ages 10+)

Contents:
I. User Guide
II. Parameters to be reported for polysomnography
III. Technical and digital specificatioins
IV. Sleep staging rules
Part 1. Rules for adults
Part 2. Rules for children
Part 3. Rules for infants
V. Arousal rule
VI. Cardiac rules
VII. Movement rules
VIII. Respiratory rules
Part 1. Rules for adults
Part 2. Rules for children
IX. Home sleep apnea testing (HSAT) rules for adults
Part 1: HAST utilizing repiratory flow and/or effort parameters
Part 2: HSAT utilizing peripheral arterial tonometry (PAT)
X. Development process
XI. Procedural notes
XII. Glossary ot terms.

Contents:
Introduction to abbreviated breast magnetic resonance imaging / Christopher E. Comstock
History of MRI in breast cancer screening / Janice S. Sung and Elizabeth A. Morris
Current clinical evidence on abbreviated breast MRI / Christiane Kuhl
Technical aspects of abbreviated breast MRI : the original approach / Christiane Kuhl
Techniques for performing abbreviated breast MRI / R. Edward Hendrick
Abbreviated breast MR imaging protocols and clinical implementation / Gillian M. Newstead
Interpretation guidelines / Janice S. Sung and Constance D. Lehman
MRI-guided biopsy techniques / Carol H. Lee.

Summary: This book describes 83 theories of behaviour change, identified by an expert panel of psychologists, sociologists, anthropologists and economists as relevant to designing interventions. For each theory, the book provides a brief summary, a list of its component constructs, a more extended description and a network analysis to show its links with other theories in the book. It considers the role of theory in understanding behaviour change and its application to designing and evaluating interventions.

Summary: ABC Transporters and Cancer provides invaluable information on the exciting and fast-moving field of cancer research. Here, outstanding and original reviews are presented on a variety of topics. This volume covers ABC transporters and cancer, and is suitable for researchers and students alike.

Contents:
Apical ABC transporters and cancer chemotherapeutic drug disposition / Selvi Durmus, Jeroen J.M.A. Hendrikx and Alfred H. Schinkel
Regulation of ABC transporters blood-brain barrier: the good, the bad, and the ugly / David S. Miller
Molecular basis of the polyspecificity of p-glycoprotein (ABCB1):recent biochemical and structural studies / Eduardo E. Chufan, Hong-May Sim, and Suresh V. Ambudkar
Lipid regulation of the ABCB1 and ABCG2 multidrug transporters / Csilla Hegedüs, Ágnes Telbisz, Tamás Hegedüs, Balázs Sarkadi and Csilla Özvegy-Laczka
ABC transporters and neuroblastoma / Denise M.T. Yu, Tony Huynh, Alan M. Truong, Michelle Haber and Murray D. Norris
Leukemia and ABC transporters / Yu Fukuda, Shangli Lian and John D. Schuetz
Critical role of ABCG2 in ALA-photodynamic diagnosis and therapy of human brain tumor / Toshihisa Ishikawa, Yoshinaga Kajimoto, Yutaka Inoue, Yoji Ikegami and Toshihiko Kuroiwa
Role of ABC transporters in fluoropyrimidine-based chemotherapy response / Anne T. Nies, Tarek Magdy, Matthias Schwab and Ulrich M. Zanger.

Summary: Clear and concise, this easy-to-use book offers an introductory course on the language of gene cloning, covering microbial, plant, and mammalian systems. It presents the nuts and bolts of gene cloning in a well-organized and accessible manner. Part I of this book outlines the essentials of biology and genetics relevant to the concept of gene cloning. Part II describes common techniques and approaches of gene cloning, ranging from the basic mechanics of DNA manipulation, vector systems, process transformation, to gene analysis. Part III & IV present application technologies of major impact in agriculture, biomedicine, and related areas. The ABCs of Gene Cloning, Third Edition contains updates including a tutorial chapter on gene-vector construction, methodologies on exome sequencing in finding disease genes, revised topics on gene therapy and whole genome sequencing, new developments for gene targeting and genome editing, as well as the current state of next generation sequencing. With more than 140 illustrations, this new edition provides an invaluable text for students and anyone who have interest in gaining proficiency in reading and speaking the language of gene cloning.

Contents:
Fundamentals of Genetic Processes
Introductory Concepts
Structures of Nucleic Acids
Structures of Proteins
The Genetic Process
Organization of Genes
Reading The Nucleotide Sequence of a Gene
Techniques and Strategies of Gene Cloning
Enzymes Used in Cloning
Techniques Used in Cloning
Cloning Vectors for Introducing Genes into Host Cells
Transformation
Isolating Genes for Cloning
Impact of Gene Cloning
Improving Tomato Quality by Antisense Rna
Transgenic Crops Engineered with Insecticidal Activity
Transgenic Crops Conferred with Herbicide Resistance
Growth Enhancement in Transgenic Fish
Impact of Gene Cloning
Microbial Production of Recombinant Human Insulin
Finding Disease-Causing Genes
Human Gene Therapy
Gene Targeting
DNA Typing
Transpharmers
Bioreactors for Pharmaceutical Products
Animal Cloning
Human Genome Sequencing
Manipulating Gene Vector Constructs.

Summary: Covers novel, state-of-the-art strategies in engineering and clinical analysis. Explores approaches for analyzing abdominal imaging, including lung, mediastinum, pleura, liver, kidney and gallbladder. Offers present and future applications as applied to the abdomen and thoracic imaging with the most world-renowned scientists in these fields.

Contents:
1. Computer-Aided Diagnosis Systems for Acute Renal Transplant Rejection: Challenges and Methodologies / Mahmoud Mostapha, Fahmi Khalifa, Amir Alansary, Ahmed Soliman, Jasjit Suri, and Ayman S. El-Baz
2. Kidney Detection and Segmentation in Contrast-Enhanced Ultrasound 3D Images / Raphael Prevost, Benoit Mory, Remi Cuingnet, Jean-Michel Correas, Laurent D. Cohen, and Roberto Ardon
3. Renal Cortex Segmentation on Computed Tomography / Xinjian Chen, Dehui Xiang, Wei Ju, Heming Zhao, and Jianhua Yao
4. Diffuse Fatty Liver Disease: From Diagnosis to Quantification / Luís Curvo-Semedo, Daniel Ramos Andrade, Catarina Ruivo, Cláudia Paulino, and Filipe Caseiro-Alves
5. Multimodality Approach to Detection and Characterization of Hepatic Hemangiomas / Rajan T. Gupta and Daniele Marin
6. Ultrasound Liver Surface and Textural Characterization for the Detection of Liver Cirrhosis / Ricardo Ribeiro, Rui T. Marinho, Jasjit Suri, and J. Miguel Sanches
7. MR Imaging of Hepatocellular Carcinoma / Dong Ho Lee and Jeong Min Lee
8. Magnetic Resonance Imaging of Adenocarcinoma of the Pancreas / Richard C. Semelka, Luz Adriana Escobar, Najwa Al Ansari, and Charles Thomas Alexander Semelka
9. Quantitative Evaluation of Liver Function Within MR Imaging / Akira Yamada
10. Diffusion-Weighted Imaging of the Liver / Ali Muhi, Tomoaki Ichikawa, and Utaroh Motosugi
11. Shape-Based Liver Segmentation Without Prior Statistical Models / Ahmed Afifi and Toshiya Nakaguchi
12. CT Imaging Characteristics of Hepatocellular Carcinoma / Masahiro Okada and Takamichi Murakami
13. Clinical Applications of Hepatobiliary MR Contrast Agents / Antoine Wadih and Sebastian Feuerlein
14. Fast Object Detection Using Color Features for Colonoscopy Quality Measurements / Jayantha Muthukudage, JungHwan Oh, Ruwan Nawarathna, Wallapak Tavanapong, Johnny Wong, and Piet C. de Groen
15. Colon Surface Registration Using Ricci Flow / Wei Zeng, Rui Shi, Zhengyu Su, and David Xianfeng Gu
16. Efficient Topological Cleaning for Visual Colon Surface Flattening / Wei Zeng, Rui Shi, Zhengyu Su, and David Xianfeng Gu
17. Towards Self-Parameterized Active Contours for Medical Image Segmentation with Emphasis on Abdomen / Eleftheria A. Mylona, Michalis A. Savelonas, and Dimitris Maroulis
18. Bridging the Gap Between Modeling of Tumor Growth and Clinical Imaging / Behnaz Abdollahi, Neal Dunlap, and Hermann B. Frieboes
19. Evaluation of Medical Image Registration by Using High-Accuracy Image Matching Techniques / Zisheng Li and Tsuneya Kurihara
20. Preclinical Visualization of Hypoxia, Proliferation and Glucose Metabolism in Non-small Cell Lung Cancer and Its Metastasis / Xiao-Feng Li and Yuanyuan Ma
21. Thermoacoustic Imaging with VHF Signal Generation: A New Contrast Mechanism for Cancer Imaging Over Large Fields of View / Michael Roggenbuck, Jared Catenacci, Ryan Walker, Eric Hanson, Jiang Hsieh, and S.K. Patch
22. Automated Prostate Cancer Localization with Multiparametric Magnetic Resonance Imaging / Yusuf Artan, Imam Samil Yetik, and Masoom A. Haider
23. Ultrasound-Fluoroscopy Registration for Intraoperative Dynamic Dosimetry in Prostate Brachytherapy / Ehsan Dehghan, Nathanael Kuo, Anton Deguet, Yi Le, Elwood Armour, E. Clif Burdette, Danny Y. Song, Gabor Fichtinger, Jerry L. Prince, and Junghoon Lee
24. Multi-Atlas-Based Segmentation of Pelvic Structures from CT Scans for Planning in Prostate Cancer Radiotherapy / Oscar Acosta, Jason Dowling, Gael Drean, Antoine Simon, Renaud de Crevoisier, and Pascal Haigron
25. Propagating Segmentation of a Single Example to Similar Images: Differential Segmentation of the Prostate in 3-D MRI / Emmanouil Moschidis and James Graham
26. 3D Registration of Whole-Mount Prostate Histology Images to Ex Vivo Magnetic Resonance Images Using Strand-Shaped Fiducials / E. Gibson, M. Gaed, J.A. Gómez, M. Moussa, C. Romagnoli, S. Pautler, J.L. Chin, C. Crukley, G.S. Bauman, A. Fenster, and A.D. Ward
27. Anatomical Landmark Detection / David Liu and S. Kevin Zhou.

Contents:
Abdominal radiography
Gastrointestinal fluoroscopy
Gastric wall thickening/masses
Hollow viscus perforation
Small bowel obstruction
Bowel wall thickening
Imaging of the postoperative bowel
Mesenteric ischemia
Colorectal cancer and screening
Right upper quadrant pain
Right lower quadrant pain
Pancreatitis
Solid pancreatic masses
Cystic pancreatic lesions
Chronic liver disease
Imaging of the cirrhotic liver
Benign focal liver lesions
Cholecystitis
Jaundice
Splenomegaly/splenic lesions
Lymphadenopathy
Urolithiasis
Cystic renal masses
Solid renal lesions
Diffuse renal parenchymal disorders
Urinary tract obstruction
Urothelial lesions
Adrenal gland enlargement and nodules
Prostate imaging
Testicular lesions
Endometrial/junctional zone thickening
Focal uterine lesions
Cystic adnexal lesions
Solid adnexal lesions
Müllerian abnormalities
Pelvic floor disease
Postoperative imaging
Abdominal/pelvic trauma
Pitfalls.

Contents:
Diagnostic approach to protocoling and interpreting MR studies of the abdomen and pelvis
Liver
Gallbladder and biliary system
Pancreas
Spleen
Gastrointestinal tract
Peritoneal cavity
Adrenal glands
Kidneys
Retroperitoneum and body wall
Bladder and nongender pelvis
Male pelvis
Female urethra and vagina
Uterus and cervix
Adnexa
Maternal conditions in pregnancy
Fetus
Chest
Contrast agents
Magnetic resonance-positron emission tomography (MR-PET).

Contents:
Classification and principals of treatment
Inflammatory mediators in Intra-abdominal sepsis
Intra-abdominal sepsis and imaging considerations
High-risk patients and prognostic factors for abdominal sepsis
Acute appendicitis: what is the best strategy to treat acute appendicites (both complicated and uncomplicated)?
Acute cholecystitis
Acute cholangitis
Pyogenic liver abscess
Gastroduodenal perforations
Small bowel perforations
Acute colonic diverticulitis
Postoperative peritonitis: etiology, diagnosis, and treatment
Damage control surgery in managing abdominal sepsis (Fausto Catena, Italy)
Ongoing peritonitis
Evolving treatment strategies for severe Clostridium difficile colitis: defining the therapeutic window
Complicated intra-dominal infections: principles of antimicrobial therapy
Antimicrobial armamentarium
Antimicrobial resistance in intra-abdominal infections
The role of Candida in abdominal sepsis
The value and interpretation of microbial specimens in the management of cIAI
Appropriate antimicrobial therapy in critically ill patients
Hemodynamic support
Adjunctive therapies in abdominal sepsis
Impact and management of abdominal compartment syndrome in patients with abdominal sepsis
Thromboprophylaxis in patiens with abdominal sepsis
Nutritional support for abdominal sepsis.

Contents:
1. Immunosuppression in solid organ transplantation
2. Infection Complications after Abdominal Organ Transplantation
3. National Transplant Network. Donor selection and evaluation criteria
4. The safety of donor
5. Medical disease after abdominal solid organ transplantation and the risk of solid and hematologic malignant tumor after transplantation)
6 Indication and timing
7. The donor procurement
8. Orthotopic liver transplantation
9. Anesthetic and perioperative management for liver transplantation
10 Living donor liver transplantation
11. Hepatic Acute and chronic rejection
12. Postoperative technical complications
13. Percutaneous management of biliary and vascular complications
14. Re-transplantation (Causes, Outcome)
15. Indication and timing
16. The donor procurement: Standard technique for procurement in cadaveric donors
17. Live donor evaluation
18. Living donor nephrectomy
19. Renal Transplantation: Surgical technique
20. The intraoperative and perioperative management of Kidney transplantation
21. Kidney acute and chronic rejection
22. Kidney Transplantation: Post-Operative Technical Complications
23. Indications and timing
24. The donor procurement
25 Transplantation
26 Abdominal wall transplantation and technique
27. Anesthetic and perioperative management for Intestinal transplantation
28. Segmental Living-related Small Bowel Transplantation
29. Intestinal Acute and Chronic rejection
30. Combined Kidney-Liver Transplantation
31. Kidney-pancreas Transplantation.

Contents:
General
Basic physical and technical principles
Blood vessels : the aorta and its branches, the vena cava and its tributaries
Liver
Porta hepatis
Gallbladder
Pancreas
Stomach, duodenum, and diaphragm
Spleen
Kidneys
Adrenal glands
Bladder, prostate, and uterus
Quick guide
The sono consultant
Documentation.

Summary: Abdominal Ultrasound for Surgeons provides a comprehensive guide to the use of ultrasonography in surgical practice of abdominal diseases. The content is divided into three major sections focusing on basic principles of ultrasound, ultrasound anatomy and pathology of the abdomen, and employment of ultrasound of the abdomen in surgical practice. A final section is dedicated to the logistics of incorporating ultrasound into a surgical practice. The first section provides an introduction to the principles of ultrasonography focusing on ultrasound physics, equipment, and instrumentation. A detailed approach to the various scanning methods and image interpretation is demonstrated with illustrations, images, and video. The second section focuses on ultrasound anatomy of the abdomen. Each chapter demonstrates the normal and abnormal ultrasound anatomy of specific abdominal organ or organ systems (abdominal wall, liver, pancreas, biliary, stomach, anorectum, retroperitoneum, vascular) with illustrations and images. The current status and technique of endoscopic ultrasound of the upper and lower gastrointestinal tracks is addressed in this section. The third section provides a state-of-the-art review of the status of each major application of abdominal ultrasound in surgery. Topics range from trauma ultrasound and laparoscopic staging to techniques in ultrasound guidance and three-dimensional targeting. This section provides a comprehensive review of the employment of interventional, intraoperative, laparoscopic, transabdominal and endoscopic ultrasound. The fourth and last section addresses the practice aspects of incorporation of ultrasound into a surgical practice. Abdominal Ultrasound for Surgeons will serve as a very useful resource and guide for surgeons and students with little to some experience in ultrasound, including practicing surgeons, surgical fellows, and surgical residents.

Summary: This book presents different patient-oriented perspectives from surgeons, economic evaluation and management researchers, and business companies active in the healthcare sector, striking a balance between the appropriateness/effectiveness of treatment and efficiency/cost. It does not include technical surgical details, but instead provides the necessary knowledge regarding different groups of patients to help economic and management researchers make accurate evaluations. Although partially based on the specific case of abdominal wall surgery in the Italian health system, the book defines a model that can, with the necessary adaptations, be applied in other national contexts. It also analyzes different reimbursement systems and methods of data collection. This approach supports the evolution form evidence-based medicine (EBM) to the future of real-world data (big data analysis). Further, it highlights the critical issue of "silos" reimbursement, which is the pillar of DRG, and proposes methodology to evaluate the direct and indirect benefit and costs of surgery (for example quality of care, costs incurred in cases of surgical complications due to the use of inappropriate, low-cost material or due to surgical procedure. It is a valuable resource for clinicians, surgeons, policymakers and managers in the field.

Contents:
PART I: Abdominal wall.- 1 Epidemiology.- 2 Anatomy.- 3 Clusters of patology & interventions.- 4 Unit of wall surgery.- 5 Organization and certification of abdominal wall surgery: the German example, the easter Europe example, the Sweden example, the Spain example.- 6 Organization and certification of abdominal wall surgery: the Eastern Europe example.- 7 Organization and certification of abdominal wall surgery: the Swedish example.- 8 Organization and certification of abdominal wall surgery: the Spanish example.- 9 Devices and biomaterials: from chemistry to certification.- 10 Assistential settings.- 11 Preventing incisional hernias: closure of abdominal wall, follow-up in abdominal surgery.- PART II: Economics.- 12 Economic Evaluation and Health Technology Assessment of Healthcare Programmes.- 13 Comparative Effectiveness in Health Technology Assessment for Medical Devices.- 14 Economic evaluation of abdominal Wall Surgery (cost benefit analysis, cost effectiveness, cost-quality analysis).- 15 Cost Containement: abdominal surgery unit.- 16 The Shouldice experience.- 17 Presurgical hidden costs: imaging, assessment clinic.- 18 Postsurgical hidden costs: neuralgia.- 19 Postsurgical hidden costs: infection.- 20 Reimbursement strategies for medical devices: the case of Abdominal Wall Surgery in Italy.- 21 Economic modelling and Budget Impact Analysis in Abdominal Surgery: the case of mesh.- PART III: Outcome.- 22 How to measure outcome in surgery.- 23 Present and future of EBM.- 24 Registries: monitoring clinical ourcomes.- 25 Registries as a source of information for the purchase of devices.- PART IV: Future perspectives.- 26 Stakeholders opinions.- 27 Evolution of abdominal wall surgery in non developed countries.- 28 How social patterns affect the development of science.- 29 Ferrying to the future.

Summary: "Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up"--Publisher's description.

Contents:
Part I: Science and clincial oncology. Section A: Biology and cancer. Molecular tools in cancer research
Intracellular signaling
The cellular microenvironment and metastases
Control of the cell cycle
The pathophysiology of cancer cell death
Cancer immunology
Stem cells, cell differentiation, and cancer
Vascular and interstitial biology of tumors
Cancer metabolism
Section B: Genesis of cancer. Environmental factors
DNA damage response pathways and cancer
Viruses and human cancer
Genetic factors: hereditary cancer predisposition syndromes
Genetic and epigenetic changes in cancer
Section C: Diagnosis of cancer. Pathology, biomarkers, and molecular diagnostics
Imaging
Section D: Clinical trials. Biostatistics and bioinformatics in clinical trials
Trial design
Structures supporting cancer clinical trials
Oncology and health care policy
Section E: Prevention and early detection. Discovery and characterization of cancer genetic susceptibility alleles
Lifestyle and cancer prevention
Cancer screening and early detection
Nicotine dependence: current treatments and future directions
Section F: Treatment. Cancer pharmacology
Therapeutic targeting of cancer cells: era of molecularly targeted agents
Basics of radiation therapy
Hematopoietic stem cell transplantation
Gene therapy in oncology
Therapeutic antibodies and immunologic conjugates
Complementary and alternative medicine
Part II: Problems common to cancer and therapy
Section A: Hematologic problems and infections. Disorders of blood cell production in clinical oncology
Diagnosis, treatment, and prevention of cancer-related venous thrombosis
Infection in the patient with cancer
Section B: Symptom management. Hypercalcemia
Tumor lysis syndrome
Cancer-related pain
Cancer cachexia
Nausea and vomiting
Section C: Treatment complications. Oral complications
Dermatologic toxicities of anticancer therapy
Cardiovascular effects of cancer therapy
Reproductive complications
Paraneoplastic neurologic syndromes
Neurologic complications
Endocrine complications
Pulmonary complications of anticancer treatment
Section D: post treatment considerations. Rehabilitation of individuals with cancer
Survivorship
Second malignant neoplasms
Caring for patients at the end of life
Section E: Local effects of cancer and its metastasis. Acute abdomen, bowel obstruction, and fistula
Superior vena cava syndrome
Spinal cord compression
Brain metastases and neoplastic meningitis
Bone metastases
Lung metastases
Liver metastases
Malignancy-related effusions
Section F: Special populations. Cancer in the elderly: biology, prevention, and treatment
Special issues in pregnancy
Human immunodeficiency virus (HIV) infection and cancer
Part III: Specific malignancies. Section A: Central nervous system. Cancer of the central nervous system
Section B: Head, neck, and eye. Ocular tumors
Cancer of the head and neck
Section C: Skin. Melanoma
Nonmelanoma skin cancers: basal cell and squamous cell carcinomas
Section D: Endocrine. Cancer of the endocrine system
Section E: Thoracic. Cancer of the lung: non-small cell lung cancer and small cell lung cancer
Diseases of the pleura and mediastinum
Cancer of the esophagus and gastroesophageal junction
Section F: Gastrointestinal. Cancer of the stomach and gastroesophageal junction
Cancer of the small bowel
Colon cancer
Cancer of the rectum
Cancer of the anal canal
Liver and bile duct cancer
Carcinoma of the pancreas
Section G: Genitourinary. Cancer of the kidney
Carcinoma of the bladder
Prostate cancer
Cancer of the penis
Testicular cancer
Section H: Gynecological. Cancers of the cervix, vulva, and vagina
Cancer of the endometrium
Ovaries and fallopian tubes
Gestational trophoblastic disease
Cancer of the breast
Section I: Sarcomas. Sarcomas of bone
Sarcomas of soft tissue
Section J: Cancer of undefined site of origin. Carcinoma of Unknown Primary
Section K: Pediatrics. Pediatric solid tumors
Childhood leukemia
Childhood lymphoma
Section L: Hematological. Acute leukemias in adults
Myelodysplastic syndromes
Myeloproliferative disorders
Chronic myeloid leukemia
Chronic lymphoid leukemias
Hairy cell leukemia
Multiple myeloma and related disorders
Hodgkin's Lymphoma
Non-Hodgkin lymphoma
Cutaneous T-cell lymphoma and cutaneous B-cell lymphoma
Adult T-cell leukemia-lymphoma.

Contents:
pt. I. Science of clinical oncology
sect. A. Biology and cancer
sect. B. Genesis of cancer
sect. C. Diagnosing cancer
sect. D. Preventing and treating cancer
pt. II. Problems common to cancer and its therapy
sect. A. Hematologic problems and infections
sect. B. Metabolic and paraneoplastic syndromes
sect. C. Local effects of cancer and its metastasis
sect. D. Complications of therapy
sect. E. Special populations
pt. III. Specific malignancies.

Contents:
I. General topics
Are you ready for your surgical rotation?
Cardiopulmonary resuscitation
How to treat all cardiac dysrhythmias
How to think about shock
Congestive heart failure (CHF) and pulmonary insufficiency
Mechanical ventilation
Why get arterial blood gases?
Fluids, electrolytes, Gatorade, and sweat
Nutritional assessment, parenteral, and enteral nutrition
What does postoperative fever mean?
Surgical wound infection
Priorities in evaluation of the acute abdomen
Surgical infectious disease
Risks of blood-borne disease
Sepsis
Frailty
II. Trauma. Initial assessment
Posttraumatic hemorrhagic shock
Traumatic brain injury
Spinal cord injuries
Penetrating neck trauma
Blunt thoracic trauma
Penetrating thoracic trauma
Blunt abdominal trauma
Penetrating abdominal trauma
Hepatic and biliary trauma
Splenic trauma
Pancreatic and duodenal injury
Trauma to the colon and rectum
Pelvic fractures
Upper urinary tract injuries
Lower urinary tract injury and pelvic trauma
Extremity vascular injuries
Facial lacerations
Maxillofacial trauma
Basic care of hand injuries
Burns
Pediatric trauma
III. Abdominal surgery. Appendicitis
Gallbladder disease
Pancreatic cancer
Acute pancreatitis
Diagnosis and therapy of chronic pancreatitis
Portal hypertension and esophageal varices
Gastroesophageal reflux disease
Esophageal cancer
Acid-peptic ulcer disease
Small bowel obstruction
Intestinal ischemia
Diverticular disease of the colon
Acute large bowel obstruction
Inflammatory bowel disease
Upper gastrointestinal bleeding
Lower gastrointestinal bleeding
Colorectal polyps
Colorectal carcinoma
Anorectal disease
Inguinal hernia
Bariatric surgery
IV. Endocrine surgery. Hyperparathyroidism
Hyperthyroidism
Thyroid nodules and cancer
Surgical hypertension
Adrenal laparoscopic adrenalectomy incidentaloma
V. Breast surgery. Breast masses
Primary therapy for breast cancer
VI. Other cancers. What is cancer?
Melanoma
Non-melanoma skin cancer
Parotid tumors
Neck masses
VII. Vascular surgery. What is atherosclerosis?
Arterial insufficiency
Carotid disease
Abdominal aortic aneurysm
Venous disease
Noninvasive vascular diagnostic laboratory
VIII. Cardiothoracic surgery. Coronary artery disease
Mitral stenosis
Mitral regurgitation
Aortic valvular disease
Thoracic surgery for non-neoplastic disease
Lung cancer
Solitary pulmonary nodule
Dissecting aortic aneurysm
IX. Pediatric surgery. Hypertrophic pyloric stenosis
Intestinal obstruction of neonates and infants
Tracheoesophageal malformations
Tracheoesophageal malformations
Congenital diaphragmatic hernia
Abdominal tumors
Congenital cysts and sinuses of the neck
X. Transplantation. Liver transplantation
Kidney and pancreas transplantation
Heart transplantation
Mechanical circulatory support
Lung transplantation
Penile and scrotal urologic emergencies
Urolithiasis
XI. Urology. Renal cell carcinoma
Bladder cancer
Prostate cancer
Urodynamics and voiding dysfunction
Pediatric urology
XII. Health care. Can health care be reformed?
Ethics in the surgical intensive care unit
Professionalism
Required reading.

Summary: The natural environment for plants is composed of a complex set of abiotic and biotic stresses; plant responses to these stresses are equally complex. Systems biology allows us to identify regulatory hubs in complex networks. It also examines the molecular "parts" (transcripts, proteins and metabolites) of an organism and attempts to combine them into functional networks or models that effectively describe and predict the dynamic activities of that organism in different environments. This book focuses on research advances regarding plant responses to abiotic stresses, from the physiological level to the molecular level. It highlights new insights gained from the integration of omics datasets and identifies remaining gaps in our knowledge, outlining additional focus areas for future crop improvement research. Plants have evolved a wide range of mechanisms for coping with various abiotic stresses. In many crop plants, the molecular mechanisms involved in a single type of stress tolerance have since been identified; however, in order to arrive at a holistic understanding of major and common events concerning abiotic stresses, the signaling pathways involved must also be elucidated. To date several molecules, like transcription factors and kinases, have been identified as promising candidates that are involved in crosstalk between stress signalling pathways. However, there is a need to better understand the tolerance mechanisms for different abiotic stresses by thoroughly grasping the signalling and sensing mechanisms involved. Accordingly, this book covers a range of topics, including the impacts of different abiotic stresses on plants, the molecular mechanisms leading to tolerance for different abiotic stresses, signaling cascades revealing cross-talk among various abiotic stresses, and elucidation of major candidate molecules that may provide abiotic stress tolerance in plants.

Contents:
"Omics" : a gateway towards abiotic stress tolerance
Second messengers : central regulators in plant abiotic stress response
Signaling peptides : hidden molecular messengers of abiotic stress perception and response in plants
Reactive oxygen species (ROS) : a way to stress survival in plants
Role of cuticular wax in adaptation to abiotic stress : a molecular perspective
Abiotic stress response in plants : a cis-regulatory perspective
Multifarious role of ROS in halophytes : signaling and defense
Enhancing cold tolerance in horticultural plants using in vitro approaches
Omics-based strategies for improving salt tolerance in Maize (Zea mays L.)
Drought stress tolerance in wheat : omics approaches in understanding and enhancing antioxidant defense
Signalling during cold stress and its interplay with transcriptional regulation
Cross talk between phytohormone signaling pathways under abiotic stress conditions and their metabolic engineering for conferring abiotic stress tolerance.

Summary: This book introduces the clinical application of ABO-incompatible transplantation. In the first part, it starts with the history, blood group antigen, antibody associated with ABO blood type, pathophysiology and pathology and related knowledge. In the second part, it covers clinical experience sharing of ABO-incompatible of heart, liver, lung and kidney transplantation. It provides a systematic methodologies and protocols. .

Summary: "Abrahams' and McMinn's Clinical Atlas of Human Anatomy, 8th Edition delivers the straightforward visual guidance you need to perform confidently in all examinations and understand spatial relationships required during your medical training, while also acquiring the practical anatomical knowledge needed for your future clinical career. Respected authority Prof. Peter Abrahams and his team of leading international anatomists and radiologists link a vast collection of clinical images to help you master all the essential correlations between the basic science of anatomy and its clinical practice"--Publisher's description.

Contents:
Head, neck and brain
Vertebral column and spinal cord
Upper limb
Thorax
Abdomen and pelvis
Lower limb
Lymphatics.

Summary: "The 'Interventional Radiology' volume of the landmark reference "Abrams' Angiography" has now been expanded and thoroughly revised to reflect dynamic advances in interventional radiology. More than 60 contributors representing a "Who's Who" of the specialty provide comprehensive, step-by-step coverage of all contemporary vascular and nonvascular interventional procedures. Major sections discuss today's equipment and describe interventions for specific disorders of each organ system, as well as for trauma, pediatric diseases, abscess drainage, and miscellaneous disorders. More than 1,100 illustrations complement the text. This edition incorporates an extensive new section on interventional oncologic procedures. The section covers all organ-specific cancers for which interventional therapies are used. Other sections include artervenous malformations, liver diseases, arterial occlusive disease, aneurysms, traumatic arterial injuries, hemorrhage, and venous diseases. It also has full color and an accompanying online site to access the content anytime"--Provided by publisher.

Summary: "Urodynamics has two basic aims: To reproduce the patient's symptomatic complaints while making key observations. To provide a pathophysiological explanation by correlating the patient's symptoms with the urodynamic findings. These two basic aims are crucial to the purpose of urodynamics - essentially it is a diagnostic test that will aid in the management of patients. The need to make urodynamic observations reflects the fact that the patient's symptoms are important, but they might be somewhat misleading. Most patients with lower urinary tract dysfunction (LUTD) present to their doctor with symptoms. However, lower urinary tract symptoms (LUTS - Table 1) should not simply be taken at face value, since a range of differing mechanisms may result in rather similar symptomatic presentations. The statement "the bladder is an unreliable witness" (1) reflects how symptoms are the starting point, but do not actually identify the ultimate explanation. Since treatment should correct the underlying cause, it is necessary to identify mechanisms, avoiding assumption or prejudice coming from taking symptoms at face value. An excellent example of this is voiding LUTS in men, where the cause on urodynamic testing may prove to be bladder outlet obstruction (BOO) and/or detrusor underactivity (DUA); BOO should respond fully to surgery to relieve obstruction such as transurethral resection of prostate (TURP), while such surgery is potentially not helpful in the second (2). Voiding LUTS in males are of unreliable diagnostic value, and only slow stream and hesitancy show any correlation with the urodynamic findings of BOO (3-5). Even with flow rate assessment, one cannot be sure whether BOO is present [Figure 1.1]. The difficulty of assessing LUTD by symptoms alone is the uncertainty about establishing truly what is going on in the individual describing them"-- Provided by publisher

Contents:
Basic urodynamics and fundamental issues / Marcus Drake, Andrew Gammie, Laura Thomas, Arturo Garcia, Hashim Hashim
Applied Anatomy and Physiology / Chendrimada Madhu and Marcus Drake
The Physics of Urodynamic Measurements / Andrew Gammie
Patient Assessment / Musaab Yassin, Alan Uren, Nikki Cotterill
Treatments for Lower Urinary Tract Dysfunction / Sharon Yeo, Hashim Hashim
Uroflowmetry / Amit Mevcha, Richard Napier-Hemy
Cystometry and pressure-flow studies / Marcus Drake, Rachel Tindle, Su-Min Lee
Videourodynamics / Marcus Drake, Michelle Ong, Devang Desai, Michel Wyndaele, Mark Woodward, Hashim Hashim
Ambulatory Urodynamics / Julie Ellis-Jones, Wendy Bevan, Dharmesh Kapoor, Marcus Drake
Studies assessing urethral pressures / Dharmesh Kapoor and Marcus Drake
Non-invasive urodynamics / Alison Bray, Christopher Blake, Christopher Harding
Urodynamics in Children / Jonathan S. Ellison, Guy Nicholls, and Mark Woodward
Urodynamics in Women / Wael Agur, Ruben Trochez, Antonin Prouza, George Kasyan, Abdelmageed Abdelrahman
Urodynamics in Men / Arturo García-Mora, Connie Chew, Marcus Drake
Structural changes of the bladder outlet / Michelle Ong, Marcus Drake and Devang Desai
Neurological disease and LUTS / Marcus Drake, Jeremy Nettleton, Mo Belal
Urodynamics in older people / Su-Min Lee, Emily Henderson
Troubleshooting during urodynamics / Laura Thomas, Rachel Tindle, Andrew Gammie
Artefacts in urodynamics / Andrew Gammie
Anorectal Physiology / Laura Thomas and Kathryn McCarthy
Organisation of the Urodynamic Unit / Laura Thomas, Alexandra Bacon, Joanne Sheen and Andrew Gammie
Equipment / Andrew Gammie
Working with limited resources / Andrew Gammie, Laura Thomas, Marcus Drake, Eskinder Solomon
Research evidence on the clinical role of urodynamics / Andrew Gammie, Marcus Drake and Hashim Hashim.

Summary: For more than 40 years, Auditory Brainstem Responses (ABRs) have been used as a diagnostic tool for hearing disorders and brainstem disorders in the pediatric audiology and neurotology and child neurology. While there are many publications in this field, this new volume will review hearing problems and neurological disorders in babies, infants and children, and discuss important new advances such as ABR figure and threshold changes with infant development. The book will also cover auditory neuropathy, its numerous and new sub-classifications. Readers will be thoroughly briefed on all the new perspectives in interpreting data. Researchers and clinicians will find the text to be a valuable tool in the correct diagnosis of hearing problems and neurological diseases among babies and infants.

Contents:
Part 1 Introduction
1 History of ABR and EABR
Part 2 ABRs
2 Origins of ABR
3 Gestational development of the human auditory system including the cochlea and the central auditory pathways
4 ABR recording technique and the evaluation of peripheral hearing loss
5 Auditory neuropathy spectrum disorders
6 Normalization and deterioration of ABR configuration in child neurology
7 Hypoxic and Anoxic Brain Damage
8 Only wave I, II of the ABR with residual hearing acuity
9 Auditory agnosia and later cortical deafness in a child over 29 years follow-up
Part 3 Electrically Evoked ABRs (EABRs)
10 Electrically evoked Auditory Brainstem Responses (EABRs), Recording Techniques, Normal (Control) and Abnormal Waveforms of the EABR
11 Inner ear malformation and cochlear nerve deficiency
12 Auditory neuropathy
Part 4 Particular Topics
13 Common Cavity Deformity
14 Galvanic VEMP.

Summary: This book serves as a tool for general psychiatrists, medical students, residents, and fellows looking for a clinically relevant and high-yield overview of addiction psychiatry in preparation for their board exams - or for everyday clinical practice. Written by expert educators in addiction psychiatry, the text is organized by substances misused and populations affected. This book serves as both a primary learning tool for those new to the field, as well as a reference for those working in addiction treatment. Each chapter begins with summaries of high yield clinical pearls, followed by general information including treatment, and then ends with accompanying board-style review questions. The scope includes understanding substances of misuse and substance use disorders (SUDs), how to evaluate, diagnose, and monitor SUDs, how to treat SUDs both pharmacologically and behaviorally, and critical information for specific populations of patients. Absolute Addiction Psychiatry for Clinical Practice and Review is an excellent resource for all medical students, residents, fellows, and professionals taking certification exams in addiction, including those in psychiatry, addiction medicine, emergency medicine, internal medicine, pain medicine, and others. The chapter "Laboratory Testing for Substance Use Disorders" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Contents:
Part I: Introduction, Evaluation, Treatment
Health Services for Addiction Treatment and Levels of Care
Laboratory Testing for Substance Use Disorders
Epidemiology, genetics, and neurobiology of substance use and disorders
Screening, Evaluation and Diagnosis of Substance Use Disorder
Psychosocial Treatment of Substance Use Disorders
Recovery from Addiction: Maintenance and Preventing Relapse
Part II: Addictions and their Treatments
Nicotine
Alcohol
Benzodiazepines and other Sedatives, Hypnotics, and Anxiolytics
Cannabinoids
OPIOIDS
Stimulants: Caffeine, Cocaine, Amphetamine and Other Stimulants
Steroids, Dissociatives, Club Drugs, Inhalants, and Hallucinogens
Behavioral Addiction
Part III: Populations
Adolescents and Students
Women and Pregnancy
Lesbian, Gay, Bisexual, Transgender, Queer or Questioning, Intersex, Asexual or Allied
Underserved Populations
Older Adults
Professionals
Part IV: Other Topics
Co-occurring Medical Disorders
Co-occurring Psychiatric Disorders
Prevention, Public Health, and Public Policy
Ethical and Legal Considerations.

Summary: This book offers a comprehensive review of allergy and immunology, specifically dedicated as a board review preparation. The book is a collective effort and participation of over 90 well known allergists, immunologists, and rheumatologist who are academician and or practitioners. Chapters are presented in a " Case-Based" format. Each chapter presents 2 cases; each case is followed by multiple choice questions/ answers and discussions. Each chapter also offers a list of specific references used in the text, that will enhance the readers' portfolio of resources. Allergy and Immunology Board Review is a must-have resource for allergy & immunology fellows-in-training and all allergy practitioners as well as any medical provider including residents, medical students and allied health who rotate in allergy divisions.

Contents:
Innate and Adaptive Immunity
Immune Cells and Functions
HistocompatIbility Antigens (HLA) and Transplantation
Allergic Diseases of the Eye
Allergic Rhinitis
Otitis Media
Asthma
Cough and Allergic Diseases
Hypersensitivity Pneumonitis
Allergic Bronchopulmonary Aspergillosis
Food Allergy
Eosinophilic Disorders
A Case-Based Board Review of Angioedema and Urticaria
Atopic Dermatitis
Allergic Contact Dermatitis
Insect Allergy
Latex Allergy
Drug Allergy
Autoimmunity
Vasculitis
B Cell Deficiency
T Cell Deficiency
Combined Immunodeficiency Disorders
Human Immunodeficiency Virus (HIV) Infection and AIDS
Anaphylaxis
Diagnostic Testing in Allergic Diseases
Antihistamines and Corticosteroids
Bronchodilators
New Asthma Therapeutics
Vaccination
Allergen Immunotherapy.

Summary: This book presents over 500 breast imaging questions with detailed answers to prepare readers for the Radiology Core Exam. Radiology residents looking for preparation materials to use for the Core Exam are often frustrated with the lack of resources available. This book addresses that lack by providing an informative and invaluable high-yield breast imaging case review book for board review and lifelong learning purposes. Editors and authors have collected numerous high quality breast imaging cases that directly align with each diagnosis the Core Exam has included in their study guide. Cases include modalities from mammogram, ultrasound, and MRI. High quality images are included for each case. The book is structured to follow the layout and topics of the ABR Study Guide, making all material boards-relevant. Within each section, cases are presented with boards-style multiple choice questions and detailed explanations, giving the reader over 500 breast imaging questions to learn from. Cases will include diagnosis, etiology, imaging characteristics, and management. Additional topics related to boards preparation and clinical practice are also addressed, including indications for screening, regulations, physics, and quality/safety. This is an ideal guide for radiology residents preparing for the breast imaging portion of their Radiology Core Examination, and for continued practice and learning for practicing radiologists.

Contents:
Regulations and Standard of Care
BI-RADS Terminology
Screening Mammogram
Diagnostic Mammogram & US
MRI
Interventional Procedures
Pathology
Male Breast
Implants
Breast Cancer Work up and Surgical Planning
Post surgical Breast
Physics. .

Summary: This concise review book provides a set of evidence-based and up-to-date study questions that demonstrate knowledge of common neurological diseases. Presented in a case-based format, each chapter includes several questions that are intended for medical students, residents rotating through neurology, and neurologists looking for study sources. Filling a need for a supplemental resource to use when studying for board exams, particularly the NBME and RITE, Absolute Case-Based Neurology serves as an invaluable guide to neurology rotations, tests and daily practice.

Contents:
Neuroanatomy
Headache
Demyelinating Diseases
Epilepsy
Dementia
Vertigo
Pediatric Neurology
Movement Disorders
Neuromuscular Disorders
Spinal Cord/Cauda Equina
Ischemic Stroke and Hemorrhagic Stroke
Increased Intracranial Pressure (ICP)
Head Trauma
Meningitis and Encephalitis
Toxic and Metabolic encephalopathy
.

Summary: This book contains the most essential information needed for an epilepsy/ EEG rotation. Chapters are formatted with bullet points and feature clinical pearls. Concise and easy-to-read, this quick reference provides neurology residents, clinical neurophysiology and epilepsy fellows, and other clinicians with the most critical information in epilepsy and EEG in a simplified, yet comprehensive format. Divided into two sections, the book first covers the diagnosis, characteristics, and treatment of epilepsy. The second section focuses on EEG placement, procedures, and patterns in various neurological disorders.

Contents:
What is not a Seizure?
Seizures and Epilepsy
Treatment of Seizures
Catamenial Epilepsy
Electrode Placement and Montages
Normal EEG
Normal EEG Variants
EEG Artifacts
Activation Procedures
Interictal Abnormal EEG Patterns
Ictal EEG Patterns
Encephalopathies and EEG
Brain Death and EEG.

Summary: This book provides a comprehensive yet concise review of geriatric psychiatry in preparation for the board exam, or for reference during practice. Written by experts in the field, this text thoroughly reviews over 500 developmental, biological, diagnostic, and treatment questions for board certification. Unlike any other text on the market, this book takes a broader approach to the subject, making it accessible for physicians as well as other clinicians, including nurses, therapists, and social workers. Absolute Geriatric Psychiatry Review is an excellent resource for all clinicians who will care for the mental health of aging patients, including psychiatrists, neurologists, psychologists, therapists, nurses, social workers, nursing home administrators, and all others.

Contents:
Intro
Preface
Contents
Contributors
Part I: Developmental, Psychological and Social Aspects of Aging
Chapter 1: Life Course: Developmental and Transitional Events
Questions
Answers
Further Reading
Chapter 2: Demography and Epidemiology
Questions
Answers
Further Reading
Chapter 3: Culture and Gender
Questions
Answers
Further Reading
Chapter 4: Family and Community
Questions
Answers
Further Reading
Chapter 5: Ethics and Forensics
Questions
Answers
Further Reading
Chapter 6: Economics and Health Policy
Questions Answers
Further Reading
Part II: Biological Aspects of Aging
Chapter 7: Neuroanatomy and Neuropathology
Questions
Answers
Further Reading
Chapter 8: Biochemistry and Neuropharmacology
Questions
Answers
Further Reading
Chapter 9: Anatomy and Physiology
Questions
Answers
Further Reading
Part III: Psychiatric Diagnosis
Chapter 10: Neurocognitive Disorders
Questions
Answers
Further Reading
Chapter 11: Depressive Disorders and Bipolar and Related Disorders
Questions
Answers
Further Reading
Chapter 12: Sleep-Wake Disorders Questions
Answers
Further Reading
Chapter 13: Schizophrenia and Other Psychotic Disorders
Questions
Answers
Further Reading
Chapter 14: Substance-Related and Addictive Disorders
Questions
Answers
Further Reading
Chapter 15: Anxiety Disorders and Obsessive Compulsive and Related Disorders
Questions
Answers
Further Reading
Chapter 16: Sexuality, Gender Dysphoria, and Paraphilic Disorders
Questions
Answers
Further Reading
Part IV: Diagnostic Methods
Chapter 17: Interviewing and History Taking
Questions
Answers
Further Reading Chapter 18: Mental Status Examination
Questions
Answers
Further Reading
Chapter 19: Functional Assessment
Questions
Answers
Further Reading
Chapter 20: Psychological and Neuropsychological Testing
Questions
Answers
Further Reading
Chapter 21: The Neurological Examination
Questions
Answers
Further Reading
Chapter 22: Clinical Laboratory Testing
Questions
Answers
Further Reading
Chapter 23: Structural and Functional Imaging
Questions
Answers
Further Reading
Part V: Treatments
Chapter 24: Pharmacokinetics and Pharmacodynamics Questions
Answers
Further Reading
Chapter 25: Cytochrome P450
Questions
Answers
Further Reading
Chapter 26: Antidepressants
Questions
Answers
Further Reading
Chapter 27: Mood Stabilizers
Questions
Answers
Further Reading
Chapter 28: Antipsychotics
Questions
Answers
Further Reading
Chapter 29: Anxiolytics
Questions
Answers
Further Reading
Chapter 30: Hypnotics
Questions
Answers
Further Reading
Chapter 31: Cognitive Enhancers
Questions
Answers
Further Reading
Chapter 32: Stimulants
Questions
Answers

Summary: This concise guide covers the evolution and expanding scope of hospital medicine and the variety of clinical, ethical and administrative situations a Hospitalist encounters. 500 questions on inpatient care, co-management of patients and hospital system management are provided with the goal of assessing clinical and academic competency. Questions feature actual cases with evidence-based solutions. Useful to physicians, house staff and advanced nurse practitioners, this up-to-date referenced learning text encompasses all aspects of hospital care.

Contents:
Inpatient Care
Consultative and Co-Management
Hospital Systems Management.

Summary: Written in a succinct question and answer format, this comprehensive resource covers all areas of nephrology and common clinical scenarios. Nearly 1000 questions with detailed answers provide nephrology fellows, practicing nephrologists and clinicians a better understanding of nephrology and aid preparations for nephrology and internal medicine boards. Absolute Nephrology Review features the latest evidence and guidelines while fulfilling a critical need within the nephrology community.

Contents:
1. Fluids, Electrolytes, and Acid-Base Disorders
2. Disorders of Mineral Metabolism and Nephrolithiasis
3. Acute Kidney Injury
4. Chronic Kidney Disease
5. Glomerular, Tubulointerstitial, and Vascular Diseases
6. Genetic Diseases and Pregnancy
7. Hypertension
8. Renal Pharmacology
9. Hemodialysis
10. Peritoneal Dialysis
11. Transplantation.

Summary: Written in a succinct question and answer format, this comprehensive book is a resource on all areas of nephrology and common clinical scenarios. The updated volume covers the basic physiology of fluids, electrolytes and acid-base problems, renal disorders and management, chronic kidney disease, hypertension, and other essential subjects. The nearly 1000 detailed questions and answers prepare readers for nephrology and internal medicine boards and provide a better understanding of nephrology as a whole. This new edition of Absolute Nephrology Review features the latest evidence and guidelines needed by nephrology fellows, practicing nephrologists, and clinicians.

Contents:
Intro
New Nomenclature for Kidney Function and Disease
Preface
Contents
Chapter 1: Fluids, Electrolytes, and Acid-Base Disorders
Sodium and Water Abnormalities
Potassium and Acid-Base Disorders
Chapter 2: Glomerular, Tubulointerstitial, and Vascular Diseases
Chapter 3: Calcium, Phosphorus, and Magnesium Disorders and Kidney Stones
Chapter 4: Chronic Kidney Disease
Chapter 5: Acute Kidney Injury and Critical Care Nephrology
Chapter 6: Hypertension
Chapter 7: Renal Pharmacology
Chapter 8: Genetic Diseases and Pregnancy
Chapter 9: Hemodialysis
Chapter 10: Peritoneal Dialysis
Chapter 11: Transplantation
Index

Summary: This practical question and answer book covers topics within the field of neurocritical care, including aspects of neurology, neurosurgery, general critical care, and emergency medicine. Each chapter serves as a standalone test, comprised of approximately 100 questions, and closely mimics the tone and scope of the United Council for Neurologic Subspecialties (UCNS) certification exam in neurocritical care. Rationale and discussion are provided in the answers section at the end of each exam. This practical study guide will help prepare critical care fellows and residents from a variety of backgrounds (including internal medicine, neurology, anesthesiology, and emergency medicine) for the UCNS exam.

Summary: This practical book features more than 1000 questions and answers with illustrations for pediatric neurologists, adult neurologists, general pediatricians and students taking their initial board examination and maintenance of certification. All questions are in multiple choice format and followed by the correct answer with a full explanation and appropriate references. Chapters are sectioned by different topics in pediatric neurology, including Epilepsy, Metabolic Disorders and Movement Disorders and other topics. Timely and thorough, this is a handy and succinct resource.

Contents:
Autism
Behavior Disorders
Congenital & Genetic Disorders
Demyelinating Disorders
Eating Disorders
Epilepsy
Ethics and Professionalism
Neurodegenerative Disorders
Neuro-metabolic Disorders
Headache
Developmental Disorders
Infections
Mental Retardation
Movement Disorders
Neurological complications of Systemic Diseases
Neuromuscular Disorders
Neuro-Oncology
Neuro-Ophthalmology
Neurophysiology
Sleep Disorders
Spinal Cord Disorders
Static encephalopathy/cerebral palsy/rehabilitation
Toxic Encephalopathy
Traumatic Brain Injury
Vascular.

Summary: This book provides a concise and up-to-date review of key rheumatology topics along with extensive practice questions to assist in preparing for the American Board of Internal Medicine (ABIM) Rheumatology Certification Exam. Each chapter focuses on a single disease and starts with a short review (primarily tables and figures) to highlight the main points and key issues. The review is followed by 10-20 board-style multiple choice questions with detailed explanations for each topic. The chapters and associated preparation questions are written by established experts from top institutions in the United States. The book concludes with a 50-question practice test reflecting the format used by the ABIM Board Certification Exam. Absolute Rheumatology Review is an essential resource for not only graduate students, residents, and fellows in rheumatology and internal medicine studying for board exams but also rheumatologists, physicians, and related professionals preparing for recertification.

Contents:
Introduction.-Immunological Basis of Inflammatory Arthritides
Clinical Epidemiology for Rheumatologists
Osteoarthritis
Regional Musculoskeletal Syndromes and the use of MSK Ultrasound
Infectious Arthritis
Rheumatoid Arthritis.-Psoriatic Arthritis
Axial Spondyloarthritis
Systemic Lupus Erythematosus
Sjogren's Syndrome
Systemic Sclerosis (Scleroderma)
Vasculitis
Inflammatory Myopathies
Osteoporosis
Crystal Arthritis.-Autoinflammatory Diseases
Pediatric Rheumatology for Adult Rheumatologists.-Musculoskeletal Manifestations of Systemic Diseases
Clinical Genetics in Rheumatology.

Contents:
1990. Forging the future, health objectives for the year 2000
1991. Public health and a national health program
1994. Building healthy environments
1995. Decision making in public health
1996. Empowering the disadvantaged, social justice in public health
1997. Communicating public health
1998. Public health and managed care
1999. Celebrating a century of progress in public health
2000. Eliminating health disparities.

Contents:
1. [Symposia I-III]
2. [Symposia IV-VII]
3. Colloquia I-XIV
4. General sessions A-F
5. General sessions G-J
[6] Author index
[7] Supplement I-

Summary: "The seventh biennial Harrison Survey, jointly sponsored by the Association of American Medical Colleges (AAMC) and the Society for Academic Continuing Medical Education (SACME), documents an academic enterprise that displays three major characteristics, somewhat in opposition to its traditional image as an isolated, passive educational entity. First, continuing medical education/ continuing professional development (CME/CPD) is increasingly integrated into the functions and missions of academic medical centers, academic health systems, and medical schools of the United States and Canada. Second, it demonstrates numerous examples of innovation and scholarship in educational design and operation. Finally, possibly as a result of the first two elements, there is an increased focus on assessing the impact of CME/CPD activities on learner competence, performance, and health care outcomes. The purpose of the survey is to help identify and understand the placement and alignment of the CME/CPD unit within the academic medical center (AMC). Survey findings will benefit those in the CME/CPD field who can use the data to assess and enhance the shape and scope of CME/CPD and who will share the information with AMC leaders, including deans, CEOs, and others. The survey generates broad but important findings for discussion and analysis in three areas: CME/CPD's structure, its function relative to relationships and educational methods, and its scope, reach, and impact. Throughout this report, data from the last Harrison Survey in 2013 are used for comparative purposes"--Executive summary.

Contents:
Executive summary
Background and methods
Section 1: Survey response rate and responder characteristics
Section 2: Structural elements of CME/CPD in the academic medical center
Section 3: Function of academic CME/CPD in the health care system
Section 4: Reach, scope, and impact of CME/CPD programming
Section 5: Discussion: structure, function, impact, and direction of academic CME.

Contents:
Part 1. General Considerations
1. Global Burden of Surgical Disease and the Role of Academia
2. Promoting, Developing, and Sustaining Academic Global Surgery Programs.-3. Ethics in Global Surgery
Part 2. Career
4. Preparing and Sustaining Your Career in Academic Global Surgery
5. Balancing Global Surgery with Traditional Career and Life Demands
Part 3. Clinical
6. Guidelines and Parameters for Ideal Short-Term Interactions: Disaster Relief
7. How to Set Up for an Ideal Long Term Clinical Interaction
Part 4. Research
8. Current Research Needs and Priorities
9. Research Methods Appropriate and Applicable to Global Surgery
10. Funding for Global Surgical Programs
Part 5. Education
11. Developing Educational Opportunities for Trainees on Both Sides
12. The Role of Educational Research in the Global Setting
Part 6. Resources
13. Tools Useful for the Academic Global Surgeon.

Contents:
Part I. What You Should Know Before You Start
1. The Structure of Academic Careers
2. Hiring from the Institution's Point of View
Part II. Planning and Timing Your Search
3. Becoming a Job Candidate: The Timetable for Your Search
4. Deciding Where and When to Apply
5. Building an Academic Network
6. Letters of Recommendation
7. Learning About Openings
Part III. Written Materials for the Job Search: Suggestions and Samples
8. Responding to Position Announcements
9. CVs
10. Additional Application Materials
11. Online Presence
12. Job Hunting Correspondence
IV. Conducting the Search
13. Interviewing
14. Preliminary Interviews
15. The Campus Visit
16. Job Offers, Negotiations, Acceptances, and Rejections
Part V. After You Take the Job
17. Starting the Job
18. Knowing About and Getting Tenure
19. Changing Jobs
Part VI. Additional Considerations
20. Dual-Career Couples and Pregnant on the Job Market
21. International Job Search
22. Cultural and Experiential Diversity
Part VII. Beyond Faculty Careers
23. Exploring the Expanded Job Market
Appendices
Appendix 1: National Job Listing Sources and Scholarly and Professional Associations
Appendix 2: Additional Resources
Appendix 3: Sample Application Package
Index
Comments.

Summary: This comprehensive text is the definitive academic pain medicine resource for medical students, residents and fellows. Acting as both an introduction and continued reference for various levels of training, this guide provides practitioners with up-to-date academic standards. In order to comprehensively meet the need for such a contemporary text--treatment options, types of pain management, and variables affecting specific conditions are thoroughly examined across 48 chapters. Categories of pain conditions include orofacial, neuropathic, visceral, neck, acute, muscle and myofascial, chronic urogenital and pelvic, acute, and regional. Written by renowned experts in the field, each chapter is supplemented with high-quality color figures, tables and images that provide the reader with a fully immersive educational experience. Academic Pain Medicine: A Practical Guide to Rotations, Fellowship, and Beyond is an unprecedented contribution to the literature that addresses the wide-spread requisite for a practical guide to pain medicine within the academic environment.

Summary: This volume deals with philosophically grounded theories of animal generation as found in two different traditions: one, deriving primarily from Aristotelian natural philosophy and specifically from his Generation of Animals; and another, deriving from two related medical traditions, the Hippocratic and the Galenic. The book contains a classification and critique of works that touch on the history of embryology and animal generation written before 1980. It also contains translations of key sections of the works on which it is focused. It looks at two different scholarly communities: the physicians (medici) and philosophers (philosophi), that share a set of textual resources and philosophical lineages, as well as a shared problem (explaining animal generation), but that nevertheless have different concerns and commitments. The book demonstrates how those working in these two traditions not only shared a common philosophical background in the arts curricula of the universities, but were in constant intercourse with each other.0This book presents a test case of how scholarly communities differentiate themselves from each other through methods of argument, empirical investigation, and textual interpretations. It is all the more interesting because the two communities under investigation have so much in common and yet, in the end, are distinct in a number of important ways.

Summary: Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals to Phase 1-3 human clinical trials and post-approval monitoring, as alternative models of drug development. As a case of successful integration of computational modeling and drug development, we discuss the development of oral small molecule therapeutics for inflammatory bowel disease, from the application of docking studies to screening new chemical entities to the development of next-generation in silico human clinical trials from large-scale clinical data. Additionally, this book illustrates how modeling techniques, machine learning, and informatics can be utilized effectively at each stage of drug development to advance the progress towards predictive, preventive, personalized, precision medicine, and thus provide a successful framework for Path to Cures.

Contents:
Intro; Contents; Contributors
Chapter 1: Introduction to Accelerated Path to Cures and Precision Medicine in Inflammatory Bowel Disease; Overview; LANCL2 Drug Development Use Case; Network Modeling for PD Biomarker Analyses Use Case; References
Chapter 2: Computer-Aided Drug Discovery; Overview; Structure-Based Versus Ligand-Based Modeling; Ligand-Based Modeling Approaches; Similarity Searching; Ligand-Based Pharmacophore Modeling; Quantitative-Structure Activity Relationship Modeling (QSAR); Structure-Based Modeling Approaches; Molecular Docking; Structure-Based Pharmacophore Modeling. Accelerating the Path to Precision MedicineComputational Models Used for Precision Medicine Discovery Measures Endpoints of Immune Mediated and Inflammatory Diseases; Concluding Remarks; References
Chapter 5: Development of Synthetic Patient Populations and In Silico Clinical Trials; Overview; Clinical Research and Clinical Trials; Design Strategies; Data Sources; Predictive Modeling for Precision Medicine; Data-Driven Models; Mechanistic Models; Rule-Based Models; Human Avatars: Virtual Patient Populations; Treatment Design; Data-Driven Design; Mechanistic Modeling-Based Design. Citrobacter rodentium Infection Model of Colitis MDR1a -/- Model of Colitis; Pig as Model of Colitis; Cell-Specific Knockout Mice; Animal Models Used in Drug Development for IBD; Utilization of Computational Models in Preclinical Studies; Concluding Remarks; References; Chapter 4: From Nutritional Immunology to Drug Development; Overview; Nutritional Modulation of Immune-Mediated Diseases; Important Immunometabolic Pathways; Nutrition-Based Therapeutics Used to Treat Gastrointestinal Diseases; Computational Approaches to Discover New Therapeutics: A Precision Medicine Initiative Molecular Docking and Virtual Screening Molecular Docking; Virtual Screening; Application of Molecular Dynamics Simulations in Drug Discovery; General Considerations; Applications of Molecular Dynamics in Generating Conformational Ensembles; MD and Scoring; MD to Discover Novel Binding Sites; Success Stories in Computational Drug Discovery; Concluding Remarks; References
Chapter 3: Preclinical Studies: Efficacy and Safety; Preclinical Studies: Safety; Preclinical Studies: Efficacy; Animal Models of IBD to Test Therapeutic Efficacy; DSS-Induced Colitis; Adoptive Transfer Model of Colitis. Statistical Analysis Dimensionality Reduction; Analysis of Variance; Concluding Remarks; References; Index.

Contents:
1. Accelerated predictive stability: an introduction
2. Regulatory expectations and industry practice on stability testing
3. Theory and fundamentals of accelerated predictive stability (APS) studies
4. Practical considerations
5. The humidity exposure of packaged products
6. Data evaluation and statistical methods
7. Strategies for improving the reliability of accelerated predictive stability (APS) studies
8. Integration of APS into a rapid, early clinical drug product development paradigm
9. Accelerated predictive stability (APS) regulatory strategies
10. Embedding APS within business
11. Implementing an accelerated predictive stability program
12. Accelerated stability assessment program (ASAP) applications in a postapproval environment
13. ASAP application: unstable drug candidate in early development
14. ASAP application in suspension, liquid, lyophilized, and controlled-release drug products
15. Applications of ASAP to generic drugs
16. ASAP application: nicotine lozenges
17. ASAP applications in clinical development: prediction of degradation and dissolution performance
18. Accelerated predictive stability (APS) applications: packaging strategies for controlling dissolution performance
19. Accelerated stability modeling: investigation of disintegration time of a drug product with sodium bicarbonate
20. Accelerated stability modeling: an ionic liquid drug product
21. Accelerated stability modeling: assay loss of nicotine lozenges
22. Accelerated stability modeling: desolvation of a solvate drug product.

Summary: "Beyond simulation and algorithm development, many developers increasingly use MATLAB even for product deployment in computationally heavy fields. This often demands that MATLAB codes run faster by leveraging the distributed parallelism of Graphics Processing Units (GPUs). While MATLAB successfully provides high-level functions as a simulation tool for rapid prototyping, the underlying details and knowledge needed for utilizing GPUs make MATLAB users hesitate to step into it. Accelerating MATLAB with GPUs offers a primer on bridging this gap. Starting with the basics, setting up MATLAB for CUDA (in Windows, Linux and Mac OS X) and profiling, it then guides users through advanced topics such as CUDA libraries. The authors share their experience developing algorithms using MATLAB, C++ and GPUs for huge datasets, modifying MATLAB codes to better utilize the computational power of GPUs, and integrating them into commercial software products. Throughout the book, they demonstrate many example codes that can be used as templates of C-MEX and CUDA codes for readers' projects. Download example codes from the publisher's website: http://booksite.elsevier.com/9780124080805/ Shows how to accelerate MATLAB codes through the GPU for parallel processing, with minimal hardware knowledge -- Explains the related background on hardware, architecture and programming for ease of use -- Provides simple worked examples of MATLAB and CUDA C codes as well as templates that can be reused in real-world projects."--Provided by publisher.

Contents:
Accelerating MATLAB without GPU
Configurations for MATLAB and CUDA
Optimization planning through profiling
CUDA coding with c-mex
MATLAB and parallel computing toolbox
Using CUDA-accelerated libraries
Example in computer graphics
CUDA conversion example : 3D image processing.

Contents:
The history of the treatment of mental illness
Acceptance and the recovery paradigm in mental health care
The multiple dimensions of the acceptance of mental illness
Barriers and facilitators to acceptance of mental illness
The process of acceptance of mental illness
Acceptance of mental illness among women : intersectional stigma
Acceptance of mental illness among men : exploring masculinities and mental health
Racial-ethnic cultural factors in the process of acceptance of mental illness
LGBT factors in the process of acceptance of mental illness
Clinical applications and investigation of the acceptance of mental illness.

Summary: "The use of venous access devices (VADs) is central to the care that nurses provide to patients with cancer. Oncology nurses must base their practice on evidence-based research when available, but a lack of evidence has been a professional challenge for decades. With limited research to guide practice, ongoing controversies remain regarding optimal device management. Since 1989, the Oncology Nursing Society (ONS) has provided guidelines to establish a foundation for access device management. With this new text, ONS has identified practice standards, developed from a synthesis of evidence, critical review, and analysis of aspects of access device management for which nursing is accountable. Access Device Standards of Practice for Oncology Nursing reviews the controversies in access device care, explores the range of devices currently available, details the advantages and disadvantages of each device to ensure optimal selection based on patient needs, and discusses the key legal ramifications concerning access devices and their management. With access device technology becoming more complex, this text is an essential resource for nurses practicing in a wide range of settings to ensure safe, effective care of patients with VADs."--Publisher's description.

Contents:
Access device standards, recommendations, and controversies
Short-term peripheral intravenous catheters
Midline catheters
Nontunneled central venous lines
Peripherally inserted central catheters
Tunneled central venous catheters
Implanted venous ports
Apheresis catheters
Complications of long-term venous access devices
Subcutaneous infusion devices
Arterial access devices
Intraventricular access devices
Epidural and intrathecal access devices
Intraperitoneal catheters
Pleural catheters
Ambulatory infusion pumps
Education, documentation, and legal issues for access devices.

Summary: This salient volume surveys the state of access to primary care and preventive health services by migrants, refugees, and asylum seekers across Europe. Experts in public health and allied fields identify obstacles to healthcare interventions for migrants, including costs, legal status, health-related behaviors and beliefs, and cultural and language barriers. The book includes the latest data concerning access to specific preventive services (e.g., vaccinations, colorectal screenings), specific issues of women and sexual minorities, and the potential for health promotion in prevention. Best practices for improving access are outlined as a basis for public health and policy directives toward reducing health disparities between migrant and native populations. Among the topics covered: Access to medical examination for prevention among migrants Access and barriers to infant vaccinations, female cancer screening and colorectal screening among migrant populations Provision and policy gap between the primary and preventive care required by and the care provided to LGBTQ+ migrants, refugees, and asylum seekers. Health related lifestyles and intermediate health conditions of migrants. Quality of primary healthcare and preventive health services provided to migrants Adaptations of primary health care for migrants Access to primary health care and policies on migration and health at a time of economic crisis Dedicated to bridging research and policy gaps in this vital area, Primary Care Access and Preventive Health Services of Migrants is intended for an international audience of academics, researchers, policymakers, and practitioners in public health and related disciplines. -- Publisher description.

Contents:
1. Foreword
2. Rights to primary care access and health prevention of non-nationals and migrants in the European Union Countries (Nadia Mignolli, Alessandra Fasano, Roberta Pace)
3. Access and barriers to childhood immunization among migrant populations (Pierluigi Lopalco)
4. Access to medical examination for primary prevention among migrants (Alessio Petrelli, Anteo Di Napoli, Alessandra Rossi)
5. Avoidable hospitalization among migrants and ethnic minorities in western countries (Laura Cacciani, Nera Agabiti, Teresa Dalla Zuanna, Cristina Canova)
6. Female migrants' attitudes and access to cervical and breast cancer screening in Europe (Sandra Buttigieg)
7. Access to colorectal screening (Aldo Rosano)
8. Health-related lifestyles among migrants (Teresa Spadea, Raffaella Rusciani, Luisa Mondo, Giuseppe Costa)
9. Adaptation of primary health care for migrants: recommendations and best practices (Marie Dauvrin, Bernadett Varga)
10. Health policies, patterns, and barriers to migrants' access to primary health care (Sonia Dias, Inés Fronteira , Ana Gama, J Coloma, Jorge Simões, Henrique Barros)
11. Access to primary care and preventive health services of LGBTQ+ migrants, refugees, and asylum seekers (J Namer, O Razum)
12. Concluding Remarks.

Summary: "AccessDermatologyDxRx is a comprehensive resource for all physicians and other healthcare providers including medical students, dermatology residents, internists, oncologists, and infectious disease specialists. With thousands of images that include all of the essential information to help you with clinical decision-making, this resource covers the full scope of dermatologic conditions."--Website.

Summary: Clinical cases selected from the LANGE Case Files series, edited by Eugene C. Toy, MD.

Contents:
Basic science:
Anatomy
Biochemistry
Microbiology
Neuroscience
Pathology
Pharmacology
Physiology. Clinical medicine:
Anesthesiology
Emergency Medicine
Family Medicine
Internal Medicine
Neurology
Ob/Gyn
Pediatrics
Psychiatry
Surgery.

Summary: Information to navigate the ever-evolving landscape of brain and nervous system function including interactive case studies, high-resolution images, and multimedia presentations. Designed for seasoned neurologists, residents, and students, you can find textbooks, expert-crafted summaries, drug monographs, and evidence-based practice guidelines.

Summary: "AccessPediatrics from McGraw-Hill Medical covers the entire span of pediatric practice, from neonatology through adolescent medicine. Updated regularly and optimized for viewing on any device, this comprehensive online pediatric resource provides instant access to information essential for completing evaluation, diagnosis, and case management decisions, as well as for pursuing research or self-assessment and board review -- all in one place."--Website.

Summary: This book provides a state-of-the-art look at the applied biomechanics of accidental injury and prevention. The editors, Drs. Narayan Yoganandan, Alan M. Nahum and John W. Melvin are recognized international leaders and researchers in injury biomechanics, prevention and trauma medicine. They have assembled renowned researchers as authors for 29 chapters to cover individual aspects of human injury assessment and prevention. This third edition is thoroughly revised and expanded with new chapters in different fields. Topics covered address automotive, aviation, military and other environments. Field data collection; injury coding/scaling; injury epidemiology; mechanisms of injury; human tolerance to injury; simulations using experimental, complex computational models (finite element modeling) and statistical processes; anthropomorphic test device design, development and validation for crashworthiness applications in topics cited above; and current regulations are covered. Risk functions and injury criteria for various body regions are included. Adult and pediatric populations are addressed. The exhaustive list of references in many areas along with the latest developments is valuable to all those involved or intend to pursue this important topic on human injury biomechanics and prevention. The expanded edition will interest a variety of scholars and professionals including physicians, biomedical researchers in many disciplines, basic scientists, attorneys and jurists involved in accidental injury cases, and governmental bodies. It is hoped that this book will foster multidisciplinary collaborations by medical and engineering researchers, and academicians and practicing physicians for injury assessment and prevention and stimulate more applied research, education and training in the field of accidental-injury causation and prevention.

Contents:
Introduction to and applications of injury biomechanics
Automotive field data in injury biomechanics
Medical imaging and injury scaling in trauma biomechanics
Anthropomorphic test devices and injury risk assessments
Restraint system biomechanics
Computational modeling in injury biomechanics
Computational analysis of bone fracture
Skull and facial bone injury biomechanics
Biomechanics of brain injury: a historical perspective
Biomechanics of brain injury: looking to the future
Neck injury biomechanics
Upper extremity biomechanics
Thorax injury biomechanics
Impact and injury response of the abdomen
Thoracic spine injury biomechanics
Lumbar spine injury biomechanics
Knee, thigh, and hip injury biomechanics
Leg, foot, and ankle injury biomechanics
Pain biomechanics
Thoracolumbar pain: neural mechanisms and biomechanics
Role of muscles in accidental injury
Pediatric biomechanics
Best practice recommendations for protecting child occupants
Pedestrian injury biomechanics and protection
Design and testing of sports helmets: biomechanical practical considerations
Normalization and scaling for human response corridors and development of injury risk curves
Injury criteria and motor vehicle regulations
Civil aviation crash injury protection
Ballistic injury biomechanics.

Summary: This book summarizes how the renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction and reviews the action of angiotensin converting enzyme inhibitors and AT1 receptor antagonists on reducing morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. ACEi and ARBS in Hypertension and Heart Failure is a highly practical reference reviewing the evidence and providing a rationale for the appropriate use of RAS antagonists in cardiovascular diseases. It is written in an easy-to-follow format and with many illustrations to aid clarity and the assimilation of information. Each chapter is written by established authorities in their fields who are also experienced in explaining often complex concepts. The result is a unique book which is not only comprehensive but also clear and useful for the busy medical practitioner.

Contents:
Pathogenetic mechanisms of RAS involvement in cardiovascular diseases
Antiotensin converting enzyme inhibitors and at1 antagonists for treatment of hypertension.- Renin angiotensin system antagonism in heart failure
Impact of co-morbidities on RAS inhibitors choice in hypertensive and heart failure patients
Target organ damage and RAS blockade.

Contents:
Surgical anatomy / Norbert Peter Tesch, Axel Gänsslen, Friedrich Anderhuber, Wolfgang Grechenig, and Stephan Grechenig
Biomechanics / Axel Gänsslen, Michael Nerlich, and Stephan Grechenig
Radiological diagnostics / Axel Gänsslen and Stephan Grechenig
Classification of acetabulum fractures / Axel Gänsslen, Stephan Grechenig, and Michael Nerlich
Epidemiology / Paul Schmitz, Axel Gänsslen, and Florian Baumann
Indications and planning / Michael Müller, Daniel Popp, Axel Gänsslen, and Matej Cimerman
Approaches / Axel Gänsslen, Stephan Grechenig, Norbert Peter Tesch, Friedrich Anderhuber, Wolfgang Grechenig, Hans-Gunther Clement, and Jan Lindahl
Posterior wall fractures / Axel Gänsslen, Arne Berner, Michael Nerlich, and Mario Staresinic
Posterior column fractures / Axel Gänsslen, Stephan Grechenig, Michael Nerlich, and Bore Bakota
Associated posterior column and posterior wall fractures / Veronika Matzi, Axel Gänsslen, and Michael Nerlich
Anterior wall fractures / Gloria Hohenberger, Axel Gänsslen, Paul Schmitz, Daniel Popp, and Jan Lindahl
Anterior column fractures / Axel Gänsslen, Paul Schmitz, and Michael Nerlich
Associated anterior column plus posterior hemitransverse fractures / Michael Müller, Axel Gänsslen, and Michael Nerlich
Pure transverse fractures / Axel Gänsslen, Michael Mueller, and Michael Nerlich
Transverse plus posterior wall fractures / Michael Müller, Axel Gänsslen, and Michael Nerlich
T-type fractures / Axel Gänsslen, Michael Müller, and Michael Nerlich
Both-column fractures / Axel Gänsslen, Thomas Dienstknecht, Michael Nerlich, and Jan Lindahl
Fractures in the elderly / Florian Baumann, Paul Schmitz, Michael Müller, and Axel Gänsslen
Acetabular fractures in children / Axel Gänsslen and Florian Baumann
Heterotopic ossifications / Axel Gänsslen, Johannes Weber, and Michael Müller
Thromboembolic complications / Axel Gänsslen, Johannes Weber, and Michael Müller
Special screws and views / Axel Gänsslen, Frank Hildebrand, Markus Klebingat, Michael Nerlich, and Jan Lindahl
Outcome scoring / Christian G. Pfeifer, Arne Berner, Michael Müller, and Axel Gänsslen
Femoral head fractures : Pipkin IV / Axel Gänsslen and Stephan Grechenig
Periprosthetic acetabular fractures / Axel Gänsslen, Paul Schmitz, and Frank Hildebrand.

Contents:
Practical actions for healthcare providers / Val Moore
Identifying a high quality evidence base / Paul Chrisp and Sara Twaddle
Key challenges to implementation and effective interventions / Elaine Whitby and Julie Royce
Using financial systems to support improved care / Jennifer Field
Using measurement to support change and improvements in healthcare / Nick Baillie
Conclusion and reflections / Danny Keenan and Sasha Abraham.

Summary: "The idea of person-centred health systems is widely advocated in political and policy declarations to better address health system challenges. A person-centred approach is advocated on political, ethical and instrumental grounds and believed to benefit service users, health professionals and the health system more broadly. However, there is continuing debate about the strategies that are available and effective to promote and implement 'personcentred' approaches. This book brings together the world's leading experts in the field to present the evidence base and analyse current challenges and issues. It examines 'person-centredness' from the different roles people take in health systems, as individual service users, care managers, taxpayers or active citizens. The evidence presented will not only provide invaluable policy advice to practitioners and policymakers working on the design and implementation of person-centred health systems but will also be an excellent resource for academics and graduate students researching health systems in Europe"-- Provided by publisher.

Contents:
The person at the centre of health systems : an introduction
Person-centredness : exploring its evolution and meaning in the health system context
Person-centred health systems : strategies, drivers and impacts
Achieving person-centred health systems : levers and strategies
Community participation in health systems development
Patient and public involvement in research
Listening to People : measuring views, experiences and perceptions
Choosing providers
Choosing payers : can insurance competition strengthen person-centred care?
The service user as manager of care : the role of direct payments and personal budgets
Choosing treatments and the role of shared decision-making
The person at the centre? : the role of self-management and self-management support
Patients' rights : from recognition to implementation.

Summary: This publication offers a systemic analysis of sustainability in the food system, taking as its framework the Sustainable Development Goals of the 2030 Agenda of the United Nations. Targeted chapters from experts in the field cover main challenges in the food system and propose methods for achieving long term sustainability. Authors focus on how sustainability can be achieved along the whole food chain and in different contexts. Timely issues such as food security, climate change and migration and sustainable agriculture are discussed in depth. The volume is unique in its multidisciplinary and multi-stakeholder approach. Chapter authors come from a variety of backgrounds, and authors include academic professors, members of CSO and other international organizations, and policy makers. This plurality allows for a nuanced analysis of sustainability goals and practices from a variety of perspectives, making the book useful to a wide range of readers working in different areas related to sustainability and food production. The book is targeted towards the academic community and practitioners in the policy, international cooperation, nutrition, geography, and social sciences fields. Professors teaching in nutrition, food technology, food sociology, geography, global economics, food systems, agriculture and agronomy, and political science and international cooperation may find this to be a useful supplemental text in their courses.

Contents:
Intro; Foreword; Preface; Acknowledgments; Contents; Part I: Current Issues; Understanding the Global Food System; 1 Introduction; 2 Nutrition Challenges; 2.1 Nutritional Challenges in the SDGs; 3 Food and the Environment; 3.1 Food and the Environment in the SDGs; 4 Food Loss and Waste; 4.1 Food Loss and Waste in the SDGs; 5 The Pathway Towards Sustainable and Healthy Food Systems; References; Climate Change, Sustainable Agriculture and Food Systems: The World After the Paris Agreement; 1 Introduction; 1.1 Climate Change and Agriculture 1.2 The Paris Agreement: Implications for the Agriculture Sector2 A Paradigm Shift in Agriculture: From Carbon Source to Sink; 2.1 Demand-Side Drivers of a Sustainable Food System; 2.2 Solutions and Tools; 3 Conclusions; References; Drivers of Migration in the Trans-Mediterranean Region: The Likely Role of Climate Change and Resource Security in the Geopolitical Context; 1 Introduction; 2 Climate Change Assessments: An Overview; 3 The Trans-Mediterranean Migration Routes; 4 Data and Methods; 4.1 Geographical Context; 4.2 Methods and Data for the Historical and Future Analysis; 4.2.1 Climate 2 The Roles of the Eco-Agri-Food System in Disease Incidence2.1 Hunger-Related Morbidity, Obesity, Diabetes Mellitus and Metabolic Disorders; 2.1.1 Extent; 2.1.2 Some Societal Costs; 2.1.3 The Role of Diets; 2.1.4 The Role of Food Quality; 2.1.5 The Role of the Agri-Environment; 2.2 Cardiovascular Diseases; 2.2.1 Extent; 2.2.2 Some Societal Costs; 2.2.3 The Role of Diets; 2.2.4 The Role of Food Quality; 2.2.5 The Role of the Agri-Environment; 2.3 Infectious Diseases: Food-Borne and Zoonotic Diseases; 2.3.1 Extent; 2.3.2 Societal Costs; 2.3.3 The Role of Diets; 2.3.4 The Role of Food Quality 3.1 The Mediterranean Diet for Prevention of Cardiovascular Disease, Diabetes and Cancer3.2 Characteristics of the Mediterranean Diet; 3.3 Mediterranean Diet and Chronic Degenerative Diseases: Insights on Potential Mechanisms; 3.3.1 Dietary Fat; 3.3.2 Carbohydrate Rich Foods; 3.4 Towards a Comprehensive Nutritional Approach to Prevent Chronic Non Communicable Diseases: The Role of the Traditional Mediterranean Diet; 4 Possible Role of Nutrition to Prevent Chronic Degenerative Diseases and Improve Health Span; 5 Conclusion; References; Eco-Agri-Food Ecology and Human Health; 1 Introduction 4.2.2 Water Resources4.2.3 Agriculture; 5 Results; 5.1 Climate; 5.2 Water Resources; 5.3 Agriculture; 6 Conclusions and Recommendations; References; Nutrition, Health and Dietary Trends; 1 Nutrition and Global Non-communicable Diseases; 2 Evolution of Nutrition Guidelines: A Shift from Nutrients to Dietary Patterns; 2.1 Nutrient-Disease Risk Model; 2.2 Dietary Pattern-Based Clinical Practice Guidelines; 3 The Relationship Between Dietary Patterns and Chronic Non-communicable Diseases: The Mediterranean Diet

Contents:
v. 1. Biographie
v. 2. Bibliographie
v. 3. Briefwechsel

Summary: "A brief, highly readable book providing the clinician with a straightforward approach to solving even the most complex acid-base, fluids, and electrolyte problems. Begins with the basic physiology that is key to understanding clinical water, electrolyte, and acid-base disorders. Useful for medical students, interns and residents, nurses responsible for IV fluid therapy, physician assistants, and first year nephrology fellows. Numerous case examples." -- Provided by publisher.

Contents:
Preface
Chapter 1. The Basics
Chapter 2. IV Solutions and IV Orders
Chapter 3. Hyponatremia
Chapter 4. Hypernatremia
Chapter 5. Hypokalemia
Chapter 6. Hyperkalemia
Chapter 7. Metabolic Acidosis
Chapter 8. Metabolic Alkalosis
Chapter 9. Three-Step Diagnosis of Acid-Base Disorders
Chapter 10. Case examples
Index.

Summary: This book provides a concise yet comprehensive overview of acid-base disorders. Each chapter reviews an acid-base disorder, covering pathophysiology, evaluation, and management of the disorder. The chapters include clinical cases and a Q & A section, based on scenarios and questions that clinicians regularly encounter when treating patients with these disorders. The book concludes with two chapters on acid-based disorders in special patient populations, including critically ill patients, pregnant patients, and surgical patients. Written by an expert in the field, Acid-Base Disorders: Clinical Evaluation and Management is a state-of-the-art resource that should assist clinicians and practitioners in managing patients with acid-base disorders.

Contents:
Introduction to Acid-Base
Basic Acid-Base Chemistry and Physiology
Methods to Assess Acid-Base Disorders
Acid-Base Disorders: General Considerations and Evaluation
Lactic Acidosis
Ketoacidosis
Toxin-Induced Acid-Base Disorders
Renal Tubular Acidosis
Acid-Base Disorders in Gastrointestinal Diseases
Acid-Base Disorders in Kidney Disease
Metabolic Alkalosis
Respiratory Acidosis
Respiratory Alkalosis
Mixed Acid-Base Disorders
Drug-Induced Acid-Base Disorders
Acid-Base Disorders in Critically Ill Patients
Acid-Base Disorders in Liver Disease
Acid-Base Disorders in Total Parenteral Nutrition
Acid-Base Disorders in Pregnancy
Acid-Base Disorders in Surgical Patients.

Summary: This book examines the short- and long-term impact of ACL injuries, covering training programs shown to reduce the rate of injuries in female athletes, and post-surgical rehabilitation for reducing the risk of future injury. Includes many color illustrations.

Contents:
Part I. Anatomy and Histology of the ACL
Chapter 1. Functional Anatomy of the ACL Fibers on the Femoral Attachment
Chapter 2. The Anatomical Features of ACL Insertion Sites and Their Implications for Multi-Bundle Reconstruction
Chapter 3. Discrepancy Between Macroscopic and Histological Observations
Chapter 4. Tibial Insertion of the ACL: 3D-CT Images, Macroscopic, and Microscopic Findings
Chapter 5. Mechanoreceptors in the ACL
Part II. Biomechanics of the ACL
Chapter 6. Mechanical Properties and Biomechanical Function of the ACL
Chapter 7. Biomechanics of the Knee with Isolated One Bundle Tear of the Anterior Cruciate Ligament
Chapter 8. Function and Biomechanics of ACL Remnant
Chapter 9. Biomechanics of Single- and Double-Bundle ACL Reconstruction
Chapter 10. ACL Injury Mechanisms
Part III. Diagnostics of ACL Injury
Chapter 11. Physical Examinations and Device Measurements for ACL Deficiency
Chapter 12. Diagnostics of ACL Injury Using Magnetic Resonance Imaging (MRI)
Chapter 13. Diagnosis of Injured ACL Using Three-Dimensional Computed Tomography: Usefulness for Preoperative Decision Making
Part IV. Basic Knowledge of ACL Reconstruction
Chapter 14. Graft Selection
Chapter 15. Portal Placement
Chapter 16. Femoral Bone Tunnel Placement
Chapter 17. Tibial Bone Tunnel Placement in Double-Bundle Anterior Cruciate Ligament Reconstruction Using Hamstring Tendons
Chapter 18. Tensioning and Fixation of the Graft
Chapter 19. Tendon Regeneration after Harvest for ACL Reconstruction
Chapter 20. Second-Look Arthroscopic Evaluation after ACL Reconstruction
Chapter 21. Bone Tunnel Changes After ACL Reconstruction
Chapter 22. Graft I impingement
Chapter 23. Fixation Procedure
Part V Multiple bundle ACL Reconstruction
Chapter 24. Single- vs. Double-Bundle ACL Reconstruction
Chapter 25. Anatomic Double-Bundle Reconstruction Procedure
Chapter 26. Triple-Bundle ACL Reconstruction with the Semitendinosus Tendon Graft
Part VI. ACL Augmentation
Chapter 27. History and Advantages of ACL Augmentation
Chapter 28. Surgical Technique of ACL Augmentation
Part VII. ACL Reconstruction Using Bone-Patella Tendon-Bone
Chapter 29. An Overview
Chapter 30. Anatomical Rectangular Tunnel ACL Reconstruction with a Bone-Patellar Tendon-Bone Graft
Chapter 31. Rectangular vs. Round Tunnel
Part VIII. Computer-Assisted Navigation in ACL Reconstruction
Chapter 32. Intraoperative Biomechanical Evaluation Using a Navigation System
Chapter 33. Application of Computer-Assisted Navigation
Part IV. ACL Injury in Patients with Open Physes
Chapter 34. ACL Reconstruction with Open Physes
Chapter 35. Avulsion Fracture of the ACL
Part V. Revision ACL Reconstruction
Chapter 36. Double-Bundle Technique
Chapter 37. Bone-Patellar Tendon-Bone Graft via Round Tunnel
Chapter 38. Anatomical Revision ACL Reconstruction with Rectangular Tunnel Technique
Chapter 39. One- vs. Two-Stage Revision Anterior Cruciate Ligament Reconstruction
Part VI. Complications of ACL Reconstruction
Chapter 40. Complications of ACL Reconstruction
Part VII. Future of ACL Reconstruction
Chapter 41. Future Challenges of Anterior Cruciate Ligament Reconstruction: Biological Modulation Using a Growth Factor Application for Enhancement of Graft Healing
Chapter 42. Strategies to Enhance Biological Tendon-Bobe Healing in Anterior Cruciate Ligament Reconstruction
Chapter 43. Tissue engineering approach for ACL healing.

Contents:
Part 1: Overview of ACLS. Introduction ; Systems of care ; Systematic approach
Part 2: Preventing arrest. Recognition: signs of clinical deterioration ; Acute coronary syndromes ; Acute stroke ; Bradycardia ; Tachycardia: stable and unstable
Part 3: High-performance teams. High-performance team roles and dynamics ; Respiratory arrest ; Cardiac arrest: VF/pVT ; Cardiac arrest: PEA and asystole ; Cardiac arrest: selected special situations ; Post-cardiac arrest care
Appendices: Testing checklists and learning station checklists ; ACLS pharmacology summary table ; Science summary table ; Glossary.

Summary: This book brings together world-famous acne researchers and specialists to compile a source of comprehensive, state-of-the-art information for management of acne. It examines acne as a chronic skin disease from pathogenesis to treatment. The book covers the clinical aspects of acne, topical treatments, light therapies, environmental factors and more alongside real patient photos from around the world. Treatments that chapters explore include photodynamic therapy and topical retinoids. In addition to genetic and hormonal causes of acne, chapters also include discussions on the connections between acne and diet, and acne and environmental factors. International contributors make this text unique in that it can focus solely on acne but also include international factors. Throughout the text, authors present the most up-to-date knowledge of acne pathophysiology, clinical features, differential diagnosis, treatment, and more. Pathophysiology, in particular, includes information on bacteria, immunity, endocrinologic factors, various deteriorating factors and environmental factors. As for clinical features, adult acne, differences in clinical patterns by region and race, and acne fulminans are covered. Regarding treatment, the latest knowledge on existing treatments or treatment methods, new drugs, and core outcome measures are mentioned. Acne: Current Concepts and Management is written for the dermatologist community from resident to researcher to privately practicing clinician.

Contents:
Chapter 1: Update on Cutibacterium acnes
Chapter 2: Updates in Isotretinoin
Chapter 3: Developing a Core Outcome Set for Acne Clinical Trials: Towards Standardization and Harmonization
Chapter 4: Adult Acne Vulgaris
Chapter 5: Topical Retinoids and Acne.-Chapter 6: New Drug Developments in Acne
Chapter 7: Scientific Connection between Acne and Diet
Chapter 8: Photodynamic Therapy for Acne Vulgaris: Mechanism and Clinical Practice
Chapter 9: Insulin Resistance Associated Acne
Chapter 10: Acne fulminans
Chapter 11: Acne and Environmental Factors
Chapter 12: Acne on Pigmented Skin
Chapter 13: Up-to-date Therapeutic Approaches for Acne Scars in a Korean Dermatology Clinic
Chapter 14: Innate and Adaptive Immunity in Acne vulgaris
Chapter 15: Clinical Features and Differential Diagnosis of Acne Vulgaris
Chapter 16: Epidemiology of Acne in Latin America and Research News from Brazil
Chapter 17: Androgens and Acne.

Summary: Dermatologists commonly treat acne, which affects 40 to 50 million Americans each year and about 85 percent of all patients at some point in their lives. Dermatologists, primary care doctors, and pediatricians see these patients every day in practice. It is important to treat the skin effectively not only to reduce the risk of physical scarring, but also to address the negative psychosocial impact this disease carries. Improving the skin can improve self-confidence, interpersonal relationships, and performance in school or at work. Acneiform Eruptions in Dermatology is a practical, full-color guide to the differential diagnosis of acne vulgaris and the treatment of acne-like conditions. It is organized into sections by subtype of condition (e.g., infections, genetic syndromes, medication-caused) and includes a section of variants of acne that may be misdiagnosed. Within the sections, individual chapters discuss each variant of the condition and begin with a helpful bulleted summary of its defining clinical features. Extensive color clinical images appear throughout the book.

Contents:
Section 1. Acne Vulgaris
1. Acne Pathophysiology
2. Clinical Presentation of Acne
3. Topical Therapies for Acne
4. Systemic Therapies for Acne
5. Laser and Light Based Therapies for Acne
Section 2. Infectious Diseases Mimicking Acne Vulgaris
6. Bacterial Folliculitis
7. Gram Negative Folliculitis
8. Hot Tub Folliculitis
9. Pityrosporum Folliculitis
10. Tinea Barbae
11. Flat Warts
12. Molluscum Contagiosum
13. Herpes Simplex Virus
14. Varicella Zoster Virus
Section 3. Variants of Acne Vulgaris
15. Acne Conglobata
16. Acne Excoriee
17. Acne Fulminans
18. Acne Mechanica
19. Cushing Syndrome
20. PAPA Syndrome
21. Polycystic Ovary Syndrome
22. Pomade Acne
23. Post-Adolescent Female Acne
24. SAPHO Syndrome
Section 4. Genetic Syndromes Mimicking Acne Vulgaris
25. Apert Syndrome
26. Birt Hogg Dube Syndrome
27. Brooke Spiegler Syndrome
28. Cowden Syndrome
29. Gardner Syndrome
30. Gorlin Syndrome
31. Muir Torre Syndrome
32. Reed Syndrome
33. Tuberous Sclerosis
Section 5. Other Mimickers of Acne Vulgaris
34. Acne Scarring
35. Eosinophilic Pustular Folliculitis
36. Favre Racouchot
37. Hidradenitis Suppurativa
38. Perioral Dermatitis
39. Photocontact Dermatitis
40. Postinflammatory Pigmetnation
41. Pseudofolliculitis Barbae
42. Pustular Psoriasis
43. Rosacea
44. Rosacea Fulminans
45. Sarcoidosis
46. Seborrheic Dermatitis
47. Steatocystoma Multiplex
48. Xanthomas
Section 6. Pediatric Dermatoses Mimicking Acne
49. Periorifical Granulomatous Dermatitis
50. Keratosis Pilaris Atrophicans
51. Neonatal and Infantile Acne
52. Papular Granuloma Annulare
53. Precocious Puberty
Section 7. Drug Induced Acneiform Eruptions
54. Drug Induced Acneiform Eruptions.

Summary: "ACoRN (short for Acute Care of at-Risk Newborns) was developed by an expert group of Canadian neonatal care providers and educators. Since launching in 2005, ACoRN has been taught across Canada and internationally, in formats varying from 1- to 3-day local, regional, or provincial/territorial workshops to module-based learning over a period of weeks. As with many education programs, ACoRN has evolved from didactic sessions and tabletop simulations to the hands-on, simulation-based workshops utilized today. Updates to the first edition of the text were published in 2010 and 2012 to add new content (on therapeutic hypothermia, for example)"-- Provided by publisher

Contents:
Foreword
Introduction
Part I Diagnosis of acquired myopathies
Auto-Antibodies in Neuromuscular Disorders
Electromyography
Imaging of the Muscle
Peripheral Nerve Ultrasound
Magnetic Resonance Imaging of the Peripheral Nerve
Part II Clinical Entities
The Spectrum of Inflammatory Myopathies: Dermatomyositis, Polymyositis, Necrotizing Myositis and Inclusion Body Myositis
Necrotising Myopathy
Statin Myopathy
Myasthenia Gravis
Acquired Autoimmune Rippling Muscles with Myasthenia Gravis
Endocrinological Myopathies
Vitamin D deficiency in Muscle
Intensive Care Unit Acquired Weakness
Part III Neurogenic disorders
Idiopathic Chronic Immune-Mediated Neuropathies: Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy
GBS Immune Neuropathies
Amyotrophic Lateral Sclerosis
Epidemiology and Risk Factors
Paraneoplastic Diseases of the Peripheral Nervous System
Diabetic Neuropathy
Infectious Neuropathies
Toxic Neuropathies.

Summary: This book provides a state-of-the-art overview of the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic disorders. The opening section covers clinical tools with a particular focus on the role of electromyography and MRI imaging. The second section then presents the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, discussing in detail relevant clinical conditions such as including myasthenia gravis, polymyositis, and statin myopathies. The third section examines acute and chronic immune-mediated neuropathies, multifocal motor neuropathies, amyotrophic lateral sclerosis, paraneoplastic diseases, and diabetic polyneuropathy, offering clear guidance on available treatments and descriptions of the latest advances in immunotheraphy, drug therapy, and physiotherapy. This clinically oriented book also includes numerous illustrative figures and contributions by international authors from leading centers.

Contents:
Part I Diagnostic Tools
Autoantibodies in neuromuscular Disorders
Electromyography
Imaging of the Muscle
Peripheral of the Muscle
Magnetic Resonance Imaging of the Peripheral Nerve
Part II Clinical Myology Entities
The Spectrum of Inflammatory Myopathies: Dermatomyositis, Polymyositis and Inclusion-Body
Necrotizing Autoimmune myopathy
Statin Myopathy
Myasthenia Gravis
Endocrinological Myopathies
Vitamin D Deficiency in Muscle
Intensive Care Unit-Acquired Weakness
Experimental pharmacological interventions
Part III Neurogenic Disorders
Idiopathic Chronic Immune-Mediated Neuropathies: Chronic Inflammatory Demyelinating Polyradiculoneuropathy
Immune Neuropathies
Amyotrophic Lateral Sclerosis: Epidemiology and Risk
Paraneoplastic Diseases of the Peripheral Nervous System
Diabetic Neuropathy
Infectious Neuropathies
Toxic neuropathies.

Summary: Acquisition of Complex Arithmetic Skills and Higher-Order Mathematics Concepts focuses on typical and atypical learning of complex arithmetic skills and higher-order math concepts. As part of the series Mathematical Cognition and Learning, this volume covers recent advances in the understanding of children's developing competencies with whole-number arithmetic, fractions, and rational numbers. Each chapter covers these topics from multiple perspectives, including genetic disorders, cognition, instruction, and neural networks. Covers innovative measures and recent methodological advances in mathematical thinking and learning Contains contributions that improve instruction and education in these domains Informs policy aimed at increasing the level of mathematical proficiency in the general public.

Contents:
1. History of Acrodermatitis Enteropathica
2. Epidemiology and Etiology
2.1. Epidemiology
2.2. Etiology
2.2.1. Molecular Etiology of AE
2.2.2. Hypothetical Etiology 1: the Alteration of Zinc Bioavailability
2.2.3. Hypothetical Etiology 2: a Defective Zinc Transporter
2.2.4. Alternative Forms of AE-like Zinc Deficiencies
3. Analysis of Disorder
3.1. Clinical Forms of AE
3.2. Nomenclature of Zinc Deficiencies
3.3. Acquired Non-hereditary Zinc Deficiency
3.3.1. Zinc Deficient Maternal Breast Milk
3.3.2. Zinc Deficient Caused by Metabolism Disorders
4. Clinical Symptoms
5. Diagnosis
5.1. Laboratory Diagnosis of Zinc Deficiency
5.2. Histopathology
5.3. Biological Diagnosis of AE
5.4. Clinical Diagnosis
5.5. Molecular Diagnosis
5.6. Differential Diagnosis
6. Disease Course and Treatment
6.1. Treatment
7. The Role of Zinc in Different Body Systems
7.1. Biochemistry of Zinc Metabolism
7.2. Skin and Hair Physiology
7.3. Gastrointestinal System and Other Organs
7.4. Neurological Development, Growth, and Mental Status
7.5. Enzymes
7.6. Endocrine System
7.7. Metabolism of Nucleic Acids
7.8. Mitosis and Meiosis Cycles
7.9. Cell Membranes
7.10. Synthesis of Proteins and Collagen
7.11. Immune System
8. History of AE in Adults
9. Iranian Hospital Cases in Literature
9.1. Patient One
9.2. Patient Two
9.3. Patient Three
9.4. Patient Four
9.5. Zinc Deficiency Similarities to AE in Infants (Fifth Patient)
10. Clinical Research
10.1. Abstract
10.2. Synopsis of Study
10.3. Purpose of Study
10.4. The Considered Hypotheses
10.5. Introduction
10.5. Methods
10.6. Ethical Considerations
10.7. Results
10.8. Discussion
11. Evaluation of Symptoms in Razi Dermatology Hospital
12. Case Photos.

Contents:
Intro; Preface; Contents; About the Editor; Abbreviations;
1: Actin Polymerization: A Cellular Perspective for Motility; 1.1 Introduction; 1.1.1 Cancer and Polycystic Ovarian Syndrome (PCOS); 1.1.2 Age-Related Neurodegenerative Disorders; 1.2 Actin: A Vital Player in Cell Motility; 1.2.1 Swimming: A Cellular Motility Phenomenon; 1.2.2 Actin-Driven Cellular Motility; 1.2.2.1 Directional Motility; 1.2.2.2 Cytokinesis; 1.2.2.3 Organelle Transport and Protein Trafficking; 1.3 Gliding Motility; 1.3.1 Gliding Motility in Apicomplexan; Bibliography
2: Actin: The Central Ubiquitous Player in the Phenomenon2.1 Introduction; 2.2 Sequence Analysis of the G-Actin; 2.3 Structure of G-Actin; 2.3.1 3D Structure of G-Actin; 2.3.1.1 Architecture of G-Actin; 2.3.1.2 Loops; 2.3.1.2.1 S-Loop (Residues 11-16) and G-Loop (Residues 154-161); 2.3.1.2.2 H-Loop (Residues70-78); 2.3.1.3 Dnase-Binding Loop (D-Loop, Residues 38-52); 2.3.1.4 Loop 60-69; 2.3.1.5 W-Loop (Residues 165-172); 2.3.1.6 Hydrophobic Plug (H-Plug) (Residues 264-273); 2.3.1.7 C-Terminal (Residues 349-375) and N-Terminal (Residues 1-10) Loops; 2.4 Role of Metal Ions 2.5 Conformational States of Actin2.6 Upsi-Phosphate Sensing; 2.7 Filamentous Actin (F-Actin); 2.7.1 Actin Polymerization; 2.8 Mechanism of Actin Polymerization; 2.9 Kinetics of Actin Polymerization; 2.10 Thermodynamics of Actin Polymerization; 2.11 Stability of Actin Filament; 2.12 Drugs Binding to Actin; Bibliography;
3: Formin: The Multidomain Elongator of Actin Polymer; 3.1 Introduction; 3.2 Localization; 3.3 Function; 3.4 Domain Organization; 3.4.1 Formin Homology-1 (FH1) Domain; 3.4.2 Formin Homology-2 (FH2) Domain; 3.4.3 Diaphanous Autoregulatory Domain (DAD) 3.4.4 Other Accessory Domains3.4.5 Domain-Isotype Relationship; Bibliography;
4: Profilin: The Associates of Formin; 4.1 Introduction; 4.2 Functions; 4.3 Structure; 4.4 Binding Partners of Profilin; 4.5 Poly-Proline-Binding Site; 4.6 Actin-Binding Sites; 4.7 Affinity of Profilin for Actin; 4.8 Hydrophobic Core; 4.9 Regulators of Profilin; Bibliography;
5: ADF (Actin Depolymerizing Factor): The Breaker of the Polymer in Homeostasis; 5.1 Introduction; 5.2 Isoforms of ADF; 5.3 Functions; 5.4 Structure; 5.5 Stability of ADF; 5.6 Regulators of ADF; 5.6.1 PIP2; 5.6.2 Phosphorylation; 5.6.3 pH

Contents:
Epidemiology of actinic keratosis / Green, A.C
Patients' perspectives on actinic keratosis / Esmann, S.
Photodamage : all signs lead to actinic keratosis and early squamous cell cancer / Wei, J.; Kok, L.F.; Byrne, S.N.; Halliday, G.M.
Dysregulation of epidermal growth factor receptor in actinic keratosis and squamous cell carcinoma / Joseph, S.R.; Munoz, L.; Gaffney, D.C.; Saunders, N.A.; Simpson, F.
The actinic keratosis virome : can we prevent squamous cell carcinoma with a vaccine? / Frazer, I.H.
Do actinic keratoses and superficial squamous cell carcinomas have a specific immunoprofile? / Wells, J.W.
Mouse models for actinic keratosis and squamous cell carcinoma / Handoko, H.Y.; Ferguson, B.; Walker, G.J.
Keratinocyte cancer and its precursors in organ transplant patients / Jenni, D.; Hofbauer, G.F.L.
Clinical features of actinic keratoses and early squamous cell carcinoma / Wheller, L.; Soyer, P.
The many clinico-pathologic faces of actinic keratosis : an atlas / Massone, C.; Cerroni, L.
Dermoscopy of actinic keratosis, intraepidermal carcinoma and squamous cell carcinoma / Zalaudek, I.; Argenziano, G.
The future of keratinocyte skin cancer surveillance : automated image analysis to identify and monitor keratinocyte dysplasia / Hames, S.C.; Prow, T.W.
Reflectance confocal microscopy : hallmarks of keratinocyte cancer and its precursors / Prow, T.W.; Tan, J.-M.; Pellacani, G.
Optical coherence tomography and its role for delineating the thickness of keratinocyte dysplasia and neoplasia / Themstrup, L.; Jemec, G.B.E.
Teledermatology : its use in the detection and management of actinic keratosis / Janda, M.
Conventional treatment of actinic keratosis : an overview / Peris, K.; Fargnoli, M.C.
Field cancerization : from molecular basis to selective field-directed management of actinic keratosis / Philipp-Dormston, W.G.
Update on photodynamic treatment for actinic keratosis / Wiegell, S.R.
Laser treatment and its implications for photodamaged skin and actinic keratosis / de Vries, K.; Prens, E.P.
Ingenol mebutate : from common weed to cancer cure / Zarchi, K.; Jemec, G.B.E.
Oral nicotinamide and actinic keratosis : a supplement success story / Kim, B.; Halliday, G.M.; Damian, D.L.

Summary: This book will give an overview on viruses undergoing proteolytic activation through host proteases. The chapters will be organized in three themed parts, the first part describing respective viruses and their characteristics in detail. In the second part the molecular and cellular biology of the proteases involved as well as their physiological functions will be further explored. The third part will contain a chapter on protease inhibitors that are promising tools for antiviral therapy. This book will engage scholars in virology and medical microbiology as well as researchers with an interest in enzymology and protein structure and function relationship.

Contents:
Intro; Preface; Contents; Part I: Viral Proteins Activated By Host Proteases; 1: Activation of the Hemagglutinin of Influenza Viruses; 1.1 Structural Basis for Activation of HA Fusion Potential; 1.2 Structure of HA0 Cleavage Sites; 1.3 Activating Proteases; References; 2: Proteolytic Activation of Paramyxoviruses and Pneumoviruses; 2.1 Paramyxoviruses and Pneumoviruses; 2.2 The Role of Protease Cleavage in Fusion Protein Activation; 2.3 Proteases Involved in Paramyxovirus F Protein Proteolytic Cleavage; 2.3.1 Furin and Its Role in F Protein Cleavage. 2.3.2 Extracellular Cleavage of Paramyxovirus F Proteins with Monobasic Cleavage Sites2.3.3 The Henipavirus F proteins: Intracellular Cleavage by Endosomal Proteases; 2.4 Proteases Involved in Pneumovirus F Protein Proteolytic Cleavage; 2.4.1 Respiratory Syncytial Virus F Proteins: A Novel Case of Two Proteolytic Processing Events; 2.4.2 Extracellular Cleavage of F Proteins from the Metapneumoviruses; 2.5 F protein Proteolytic Processing, Pathogenesis, and Antiviral Approaches; 2.6 Proteolytic Activation of the Hemagglutinin-Neuraminidase Glycoprotein; References. 3.7.2 Peptide-Based Compounds and Small Molecules3.7.3 A Novel Cell-Based Sensor for SKI-1/S1P as a Platform for High-Throughput Drug Screening; 3.7.4 Use of the SKI-1/S1P Sensor to Predict Protease Use of Newly Emerging Arenaviruses; References; 4: Priming Time: How Cellular Proteases Arm Coronavirus Spike Proteins; 4.1 Introduction; 4.2 The Coronavirus Spike Protein: Viral Key for Entry into the Target Cell; 4.3 Proteolytic Priming of Coronavirus Spike Proteins: Basic Concepts; 4.4 Proteolytic Activation of the Spike Proteins of SARS-CoV and MERS-Co
V. 3: Cleavage of the Glycoprotein of Arenaviruses3.1 Arenavirus Structure, Genome Organization, and Basic Virology; 3.2 Arenavirus GP Structure and Function; 3.3 The Proprotein Convertase SKI-1/S1P Cleaves Arenavirus GPC; 3.4 The Mechanism of SKI-1/S1P Processing of Arenavirus GPC Differs from Cellular Substrates; 3.5 Optimized Recognition of Arenavirus GPC by SKI-1/S1P: Viral Advantage and Achilles' Heel; 3.6 The Processing of Reptarenavirus GPC Is Largely Unknown; 3.7 Targeting SKI-1/S1P-Mediated GPC Processing as an Anti-arenaviral Strategy; 3.7.1 Protein-Based Strategies. 4.4.1 Cathepsin L: Endosomal Activator of the Spike Protein4.4.2 Activation of the Spike Protein by Type II Transmembrane Serine Proteases at the Cell Surface; 4.4.3 Furin Can Activate Coronavirus Spike Proteins in the Constitutive Secretory Pathway of Infected Cells and During Viral Entry into Target Cells; References; 5: Proteolytic Processing of Filovirus Glycoproteins; 5.1 Introduction; 5.2 Biosynthesis and Maturation of Filovirus Glycoproteins; 5.3 The Role of GP in Host Cell Entry; 5.4 Proteases Responsible for GP Processing; References.

Summary: The purpose of the The Active Female: Health Issues Throughout the Lifespan, 2nd Edition is twofold: (1) to increase the awareness of wellness and fitness issues for active females and their family members; and (2) to provide an avenue for medical practitioners, allied health professionals, health educators, and certified individuals in sports medicine to gain critical, updated knowledge of a field specific to active females. Part I of the book offers a foundation to help the reader understand the interrelationship among body image concerns, the female reproductive cycle, and musculoskeletal anatomy/physiology of females that makes their health risks and concerns unique. Reproductive health is discussed by a prominent researcher in reproduction/endocrinology. An overview of the Female Athlete Triad which is a syndrome of three interrelated conditions (isordered eating, menstrual disturbances and bone loss) is presented in Part II. Physicians and certified professionals in sports medicine discuss the individual components of the triad, relating not only to the athletic female but also to the recreationally active woman throughout the lifespan. In Part III, Prevention and management of common musculoskeletal injuries is addressed by a female orthopedic surgeon who sub-specializes in treating female athletes. Finally, appropriate exercise and nutritional guidelines for active females are discussed in Parts IV-V of the book by certified professionals and licensed physicians in sports medicine. An invaluable addition to the literature, The Active Female: Health Issues Throughout the Lifespan, 2nd Edition will be of great interest to physicians, allied health care practitioners, medical/other wellness educators, and students who are interested in advancing women's health issues. Sports medicine specialists, family practitioners, gynecologists, team physicians, residents in sports medicine, athletic trainers, health educators, nurses, physicians assistants, physical therapists, sport psychologists, counselors, athletic trainers, and other members of the sports medicine team should also find this title of significant interest.

Contents:
Pt. I. Focusing on active female's health issues: unique gender related psychological and physiological characteristics of females
Pt. II. Disordered eating issues in the active female
Pt. III. Prevention and management of common musculoskeletal injuries in active females
Pt. IV. Exercise guidelines and precautions for active females
Pt. V. Nutrition, energy balance, and weight control.

Summary: "This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions."--Publisher's description.

Contents:
Activity-based protein profiling- enabling multimodal functional studies of microbial communities
Activity-based protein profiling methods to study bacteria: the power of small-molecule electrophiles
Opportunities and challenges in activity-based protein profiling of mycobacteria
Activity-based protein profiling at the host-pathogen interface
Chemical proteomic profiling of protein fatty-acylation in microbial pathogens
How to target viral and bacterial effector proteins interfering with ubiquitin signaling
ABPP and host-virus interactions
Activity-based protein profiling for the study of parasite biology
Deciphering T cell immunometabolism with activity-based protein profiling
Small-molecular inhibitors of PARPs: from tools for investigating ADP-ribosylation to therapeutics
Development of activity-based proteomic probes for protein citrullination
Recent advances in activity-based protein profiling of proteases
Opportunities for lipid-based probes in the field of immunology
Activity-based protein profiling of non-ribosomal peptide synthetases
Target identification of bioactive covalently acting natural products
Applications of reactive cysteine profiling.

Contents:
I. L'énergie (points, méridiens, circulation)
II. Le maniement de l'énergie.

Summary: "The Chinese are known to have practiced acupuncture for approximately 2,000 years. Designed specifically for health care practitioners, this book demystifies acupuncture and explains it in anatomical terms. New emphasis is made to differentiate traditional acupuncture in Oriental medicine from scientific acupuncture, which is based entirely on medical sciences. This edition is completely updated and presents the most current research. New material includes information on how to quantify pain and a new way to define acute and chronic pain"--Provided by publisher.

Contents:
Chapter 1. Introduction
chapter 2. Anatomy in acupuncture
chapter 3. Acupoints of the cranial nerves
chapter 4. Acupoints in the neck region
chapter 5. Acupoints in the upper limb
chapter 6. Acupoints in the body trunk
chapter 7. Acupoints in the lower limb
chapter 8. Physiology in acupuncture
chapter 9. Biochemistry in acupuncture
chapter 10. Pathology in acupuncture
chapter 11. Psychology in acupuncture
chapter 12. Pain and measurement
chapter 13. Good to excellent applications
chapter 14. Applications with mixed and limited results
chapter 15. Difficult patients with poor results.

Summary: This book systematically introduces the Brain in Traditional Chinese Medicine (TCM) and its acupuncture treatments. It discusses the origin and development of the TCM Brain theory, and presents current research on brain and acupuncture, the unique brain related techniques such as scalp acupuncture and Dao-qi technique, the new developing acupuncture treatment methods for brain-related conditions, such as stroke, Parkinson's, dementia, Alzheimer's disease, multiple sclerosis, traumatic brain injury, autism, cerebral palsy and depression, anxiety, bipolar disorder among others. This book is of interest to TCM and acupuncture practitioners in the West, as well as acupuncture researchers and lecturers. It gives a new understanding of the brain and treatments for brain-related conditions from a complementary medicine point of view.

Contents:
Part One. Acupuncture for Brain, Introduction and Theory
1. Brain in original Traditional Chinese Medicine
2. Acupuncture and The Brain Current Understanding
3. Acupuncture Research and the Brain
4. Acupuncture Brain. physiology and Pathology
5. Scalp acupuncture
6. Dao qi acupuncture technique
7. Abdominal acupuncture
8. Other Commonly used acupuncture techniques for Brain conditions
9. Commonly used Herb formulas for Brain Conditions
10. The Chinese View--Preserving a Healthy Functioning Brain
11. Stroke
12. Parkinson's disease
13. Dementia and Alzheimer's disease
14. Multiple Sclerosis
15. Brain Injuries
16. Cerebral palsy and Brain retardation.
17. Other neurological conditions
18. Depression
19. Anxiety
20. Bipolar Disease
21. Autism
22. Other psychological conditions
23. Other brain related conditions
Conclusion
Appendix
Index.

Summary: Acupuncture for Pain Management is intended as the premier resource for learning the fundamentals of the art of medical acupuncture. Edited by top pain medicine specialists at Harvard and UCLA, and based on their popular annual workshop at the American Society for Anesthesiologists, the book is the perfect synthesis of Western and Chinese medicine. Anesthesiologists, pain medicine specialists, primary care physicians, osteopaths, neurologists, psychiatrists, physical medicine and rehabilitation specialists, and other health professionals looking to add acupuncture to their repertoire will benefit from the concise and practical approach of the book. Features: Each individual meridian discussed in detail acupuncture for 25 clinical conditions, including headache, menstrual pain, low back pain, insomnia, and more. Aimed at acupuncturists as well as practitioners who want to add acupuncture to their clinical armamentarium.

Contents:
Part I: General Consideration
1. History of Acupuncture
2. Basic Theories of Traditional Chinese Medicine
3. Pattern Discrimination in Traditional Chinese Medicine (TCM)
4. Mechanisms of Acupuncture Analgesia
5. Common Acupuncture Practices
6. Peri-Operative Acupuncture
7. Acupuncture Pain Research: Quantitative and Qualitative
8. Auricular Acupuncture
Part II: Acupuncture Channels
9. Acupuncture Qi Flow and Points Measurement
10. Hand Tai Yin Lung Meridian
11. Hand Yang Ming Large Intestine Meridian
12. Foot Yang Ming Stomach Meridian
13. Foot Tai Yin Spleen Meridian
14. The Hand Sho Yin Heart Meridian
15. The Hand Tai Yang Small Intestine Meridian
16. Foot Tai Yang Bladder Meridian
17. Foot Shao Yin Kidney Meridian
18. The Hand Jue Yin Pericardium Meridian
19. The Hand Sho Yang Triple Energizer Meridian
20. The Foot Shao Yang Gall Bladder Meridian
21. The Foot Jun Yin Liver Meridian
22. Conception Vessel
23. Governor Vessel
24. The Extra Acupuncture Points
Part III: Clinical Conditions
25. Headache
26. Facial nerve palsy
27. Vertigo
28. Toothache
29. Neck Pain
30. Chest Pain
31. Epigastic Pain
32. Abdominal Pain
33. Dysmenorrhea
34. Upper Back Pain
35. Frozen Shoulder
36. Low Back Pain
37. Arthritis, Joint Pain
38. Coccygeal Pain
39. Elbow Pain
40. Wrist Pain
41. Ankle Pain
42. Heel Pain
43. Insomnia
44. Nausea and Vomiting
45. Sedation
46. Dizziness.

Contents:
Section I: Foundations. Principles for practice development to facilitate outcomes and productivity
Billing, reimbursement, and setting up a clinic
Anatomy and physiology of skin and soft tissue
Wound-healing physiology and factors that affect the repair process
Types of skin damage and differential diagnosis
Skin and wound inspection and assessment
Section II: Pressure ulcers. Pressure ulcers: impact, etiology, and classification
Developing and maintaining a pressure ulcer prevention program
Support surfaces
Section III: Lower extremity wounds. Lower extremity assessment
Arterial ulcers
Venous ulcers
Lymphedema
Neuropathic wounds: the diabetic wound
Foot and nail care
Section IV: Wound bed preparation. Wound infection: diagnosis and management
Wound debridement
Principles of wound healing and topical management
Section V: Biophysical and biologic agents. Cellular- and/or tissue-based products for wounds
Molecular and cellular regulators
Negative pressure wound therapy
Hyperbaric oxygenation
Electrical stimulation
Ultraviolet light and ultrasound
Section VI: Critical cofactors. Wound pain: impact and assessment
Managing wound pain
Nutritional assessment and support
Perfusion and oxygenation
Eliminating noncompliance
Section VII: Acute and traumatic wounds. Uncommon wounds and manifestations of intrinsic disease
Traumatic wounds: bullets, blasts, and vehicle crashes
Burns
Reconstructive surgery
Surgical wounds and incision care
Section VIII: Special patient populations. Skin care needs of the obese patient
Skin care needs of the neonatal and pediatric patient
Managing wounds in palliative care
Management of draining wounds and fistulas
Percutaneous tube management
Appendix A: Tool examples to support skin and wound care
Appendix B: Self-assessment exercises.

Contents:
Part I. Surgery
1. Acute Appendicitis
2. Acute Biliary Tract Diseases
3. Acute Pancreatitis
4. Nontraumatic Gastroduodenal Perforations
5. Symptomatic Abdominal Wall Hernias
6. Symptomatic Diaphragmatic Hernia
7. Intestinal Obstruction
8. Acute Inflammatory Bowel Disease
9. Spleen
10. Abdominal Trauma
11. Miscellaneous Conditions
Part II. Gynecology
12. Adnexal Torsion
13. (Isolated) Torsion of the Fallopian Tube
14. Ruptured/Bleeding Ovarian Cysts/Tumors
15. Ruptured Ectopic Pregnancy
16. Spontaneous Uterine Rupture
17. Torsion of the Gravid Uterus
18. Degenerating Uterine Myomas
19. Pelvic Inflammatory Disease and Tubo-ovarian Abscess.

Summary: This book will help readers recognize, diagnose and efficiently treat acute abdominal disorders encountered in the pregnant patient, whether associated with or incidental to the pregnancy. Includes more than 200 figures relevant to diagnosis and treatment.

Summary: This is a comprehensive practical guide to the practice of the new subspecialty of critical care echocardiography. The text covers all aspects of clinical practice and describes how to use transthoracic echocardiography to approach and manage common clinical questions. Specific emphasis is placed on the appropriate use of clinical echocardiographic data in the context of the patient's critical illness; this is illustrated by the frequent use of case studies including both still and moving echocardiographic images. The text covers assessment of, and disorders affecting, the left and right heart, including shock and sepsis. It also looks at how to interpret diastolic information during critical illness and the effect of that illness on valve disease and function. The important subject of fluid responsiveness is explored in detail, as is the influence of organ support and illness on the diagnosis of cardiac tamponade. The information given in the text is summarized using algorithms in a field guide for the critical care echocardiographer, which also provides a rapid guide to assessing time-critical patient presentations.

Summary: This pocket guide is a single-volume source of the most common and important formulas and laboratory values used in the daily practice of acute care and critical care medicine. Information is presented in outline format and as tables, graphics, and algorithms to facilitate quick look up. Acute and Critical Care Formulas and Laboratory Values is designed to help clinicians interpret clinical data, apply formulas, understand laboratory values, and integrate this information with their knowledge of pathophysiology to promote the delivery of evidence-based care. Essential formulas and laboratory values. Multiple ways to derive a value, where appropriate. Non-clinical formulas useful for understanding physiologic concepts or that underlie diagnostic tests or clinical measurement.

Contents:
Cardiovascular Formulas and Facts
Endocrinology and Metabolism Formulas
Environmental Facts and Formulas
Gastrointestinal Facts and Formulas
Hematological Facts and Formulas
Infectious Diseases Formulas and Facts
Neurological Formulas and Facts
Nutrition Formulas and Facts
Obstetrics & Gynecology Formulas and Facts
Oncology Formulas
Pediatric Formulas and Laboratory Values
Pulmonary Formulas and Facts
Renal, Fluid & Electrolyte Formulas and Facts
Statistics and Epidemiology
Toxicology Formulas and Facts
Trauma Facts and Formulas
Common Laboratory Values.

Contents:
1. An Introduction to the Acute Care for Elders / Michael L. Malone, Ji Won Yoo, and James S. Goodwin
2. The Team Approach to Interdisciplinary Care / Maryjo Cleveland, Carolyn Holder, Ariba Khan, and Aileen Jencius
3. Patient and Hospital Factors That Lead to Adverse Outcomes in Hospitalized Elders / Edgar Pierluissi, Deborah C. Francis, and Kenneth E. Covinsky
4. An Overview of Hospital-Based Models of Care / Elizabeth A. Capezuti and Marie Boltz
5. The Acute Care for Elders Unit / Robert M. Palmer and Denise M. Kresevic
6. How to Develop, Start, and Sustain an Acute Care for Elders Unit / Ellen S. Danto-Nocton, Carolyn Holder, Rebecca Ramsden, Jonny Macias Tejada, Anita Steliga, and Karen Padua
7. How to Disseminate the ACE Model of Care Beyond One Unit / Roger Y. Wong, Marsha Vollbrecht, and Patti Pagel
8. How to Use the ACE Unit to Improve Hospital Safety and Quality for Older Patients: From ACE Units to Elder-Friendly Hospitals / Samir K. Sinha, Sandra Liliana Oakes, Selma Chaudhry, and Theodore T. Suh
9. ACE Unit Business Model / Kyle Allen, Peter DeGolia, Susan Hazelett, and Diane Powell
10. Models of Care to Transition from Hospital to Home / Ella Harvey Bowman, Kellie L. Flood, and Alicia I. Arbaje
11. What Is the Role of Hospitalists in the Acute Care for Elders? / Heidi L. Wald and Melissa L. P. Mattison
12. How to Improve Care for Seniors in the Emergency Department / Soryal Soryal, Marie Boltz, Scott Wilber, and Michael L. Malone
13. How to Improve Care for Older Patients in the Intensive Care Unit / Leanne Boehm, E. Wesley Ely, and Lorraine Mion
14. The Future of Acute Care for Elders / Kanwardeep Singh and Michael L. Malone.

Summary: Acute Care General Surgery provides a succinct focused overview of a myriad of general surgical emergencies. Each chapter has a concise, practical framework on the workup and management of a specific topic. The book covers a wide array of pathology from the more common appendicitis, diverticulitis and cholecystitis to those less frequently encountered such as toxic megacolon, Fournier's gangrene and volvulus. Learning objectives for each chapter are clearly defined. In addition to differential diagnosis, the work up and management is comprehensively discussed. In addition, a pithy clinical pearl is included to serve as a memory aid for each diagnosis. Upon reviewing this volume, clinicians who encounter the acute care surgical patient in their practices will be better equipped to rapidly assess, evaluate, diagnose and managing their complex and often challenging problems.

Contents:
Appendiceal Mucocele
Aute Appendicitis
Colonic Volvulus
Acute Cholecystitis/Biliary Disease
Diverticulitis of the Colon
Enterocutaneous Fistula
Fournier's Gangrene
Upper Gastrointestinal Bleeding
Lower Gastrointestinal Bleeding
Acute Anorectal Emergencies
Incarcerated Groin Hernias
Intussusception
Meckel's Diverticulitis
Necrotizing Soft Tissue Infections
Pancreatic Pseudocysts
Paraesophageal Hernia
Pneumobilia
Pneumoperitoneum
Portal Venous Gas
Small Bowel Diverticulitis
Small Bowel Obstruction
Small Bowel Perforation
Toxic Megacolon
Acute Pancreatitis
Peptic Ulcer Disease.

Contents:
Part 1. Introduction
1. Acute Care Setting
2. The Medical Record
Part 2. Body Systems
3. Cardiac System --4. Pulmonary System
5. Musculoskeletal System
6. Nervous System
7. Vascular System and Hematology
8. Gastrointestinal System
9. Genitourinary System
10. Endocrine System
Part 3. Diagnoses
11. Oncology
12. Burns and Wounds
13. Infectious Diseases
14. Organ Transplantation
15. Fluid and Electrolyte Imbalances
16. Amputation
17. Physical Therapy Considerations for Patients Who Complain of Chest Pain
Part 4. Interventions
18. Medical-Surgical Equipment in the Acute Care Setting
19. Pharmacologic Agents
20. Anesthesia: Perioperative Considerations for the Physical Therapist
21. Acute Pain Management
22. Postural Drainage
23. Functional Tests
Appendix A. Preferred Practice Patterns.

Summary: This book reviews the common clinical scenarios that might trigger emergent consultation for neurosurgical intervention, with attention to key components of the clinical interview and exam, optimal diagnostic evaluation, indications for and the goals of operative intervention, perioperative considerations, and strategies for complication mitigation. This is not a surgical atlas, but rather, a road map for the journey to the operating room door. The intent is to establish a systematic, evidence-based action plan for the patient presenting in neurologic crisis. Each chapter opens with a relevant case vignette and then unfolds through uniform sections to tell the story of how one might approach the disease entity in question, from initial request for consultation to definitive management, highlighting steps of the decision-making process. Each chapter is punctuated by 3-5 teaching pearls, summarizing these key elements. The overall goal is to create a framework for assessment that might be applied in the emergency department, the trauma bay, or the ICU when a neurologic emergency arises. The scope encompasses not only cranial and spinal trauma, but also entities such as shunt failure, stroke, aneurysmal subarachnoid hemorrhage, pituitary apoplexy, cauda equina syndrome, and central nervous system infection that might require time-sensitive intervention. An additional section addresses issues requiring emergent neurosurgical response in the ICU setting, including sudden neurologic worsening, status epilepticus, and abnormal clotting/ coagulopathy. .

Summary: "Substantially updated with more illustrations and brand-new chapters that reflect the growth and advances in the field, this latest edition of Acute Care Surgery features an editorial board drawn from the ranks of trauma surgery, emergency surgery, and critical care surgery. A comprehensive, updated, and timely overview of this fledgling specialty!"--Provided by publisher.

Contents:
Section I. Radiology basics
Section II. Abdomen
Section III. Chest
Section IV. Soft tissue
Section V. Trauma.

Summary: This pocket manual is a practically oriented, wide-ranging guide to acute care surgery general aspects and℗ℓto non-gastrointestinal emergencies. It covers the most common problems in thoracic, obstetric, gynecologic, anorectal, vascular and skin surgery and also includes chapters on postoperative complications in bariatric surgery, antibiotic management, nutrition and interventional radiology in acute care surgery. This guide stems from collaboration with the World Society of Emergency Surgery (WSES) and aims to provide general surgeons, ℗ℓresidents and trainees with a comprehensive and up-to-date overview℗ℓof the℗ℓmost relevant operative techniques and with useful℗ℓ "tips and tricks" applicable in daily clinical practice. A second volume on gastrointestinal and abdominal surgical emergencies is also available.

Contents:
1. Acute care surgery around the world: future perspectives
2. A history of acute care suregry
3. Scientific Research in emergency surgery setting
4. Organization of an acute care surgery service and patient safety management
5. Safety and the use of checklists in acute care surgery
6. Emergencies in otolaryngology
Head & Neck Surgery
7. Hemothorax, pneumothorax and chest empyema
8. Anorectal emergencies
9. Skin and Soft Tissue Infections
10. Surgical Site Infections and their Management
11. Non-Traumatic Peripheral Vascular Emergencies
12. Ruptured abdominal aortic aneurysms and major vascular injuries
13. Obstetrics-Gynecology Emergencies
14. Genito Urinary Emergencies
15. Critical Care in Acute Care Surgery
16. Septic Shock and Resuscitation Strategies
17. Antibiotic management in acute care surgery
18. Nutrition in sepsis and acute surgical patients
19. Point-of-Care Ultrasound in Critically-Ill Patients
20. Interventional Radiology for non-traumatic acute thoraco-abdominal bleeding
21. Percutaneous Techniques for Management of Intra-Abdominal Abscesses
22. Damage Control Surgery for Emergency General Surgery
23. The Abdominal Compartment Syndrome
24. Common Pediatric Surgical Emergencies
25. Common Surgical Emergencies in Transplanted Patients
26. Emergency management of caustic injuries
27. Surgical emergencies during pregnancy
28. Geriatric Emergency Surgery.

Summary: This volume focuses on acute trauma to the adult elbow, including fractures, dislocations, tendon ruptures, and vascular and nerve injuries. Each chapter addresses anatomical key features, surgical and conservative therapeutic procedures, postoperative regimes and complication strategies. International elbow experts explore a range of surgical approaches, the usage of modern implants, advances in surgical techniques, and pearls and pitfalls for each trauma entity. Moreover, the authors describe total elbow arthroplasty and radial head replacement in detail, outline current clinical outcomes, and provide recommendations for therapeutic approaches and salvage measures. The book enables the orthopedic surgeon to deal with the entire spectrum of acute simple and complex elbow injuries in adults.

Contents:
Part I. Simple elbow dislocations
Part II. posteromedial rotatory instability
Part III. Distal humerus fractures
Part IV. Proximal ulna fractures
Part V. Radial head fractures
Part VI. Monteggia fractures
part VII. Terrible triad injuries
Part VIII. Distal biceps tendon rupture
Part IX. Distal triceps tendon rupture
Part X. Vascular injury
Part XI. Nerve injury.

Contents:
Section I. Introduction
Section II. Pathophysiology
Section III. Diagnostic Strategy
Section IV. Subtypes of Acute Encephalopathy
Section V. Subtypes of Acute Encephalitis
Section VI. Encephalopathy/Encephalitis With Refractory Epileptic Status: Rima Nabbout
Section VII. Management of Acute Encephalopathy and Encephalitis.

Summary: This book assembles recent achievements in both basic research and clinical management in the field of hepatology, virology and immunology. It provides up-to-date information for clinicians who can apply the relevant knowledge to their daily clinical practice and for researchers who are interested in clinically orientated studies. The updated and detailed technology, state-of–the-art treatment strategies provided in this book serve as references for clinicians and resident physicians in the daily management of ACLF. The rationality and strategies for basic research as well as patient management in this book can also be a valuable reference for other fatal and end stage liver diseases than HBV induced ACLF. This volume 1 has 6 chapters and focuses on the definition, research technology, virology, genetics, and immunology.

Contents:
Introduction to Acute Exacerbation of Chronic Hepatitis B
Research Technology and Principles of Clinical Study
Virology
Genetics
Immunology.

Contents:
Section 1: Basics
1. Pathophysiology of ischemic stroke
2. Pathophysiology of moyamoya disease
3. Radiological assessment of ischemic stroke
4. Pathology of blood clot
Section 2: Medical Practices
5. General management & intensive care of ischemic stroke
6. Cardiac evaluation and management after ischemic cerebral stroke
7. Intravenous thrombolytic therapy
8. Pediatric ischemic stroke
Section 3: Endovascular Practices
9. History and overview
10. Clot aspiration technique
11. Stent retriever technique
12. Intracranial stenting
13. Treatment of arterial dissection
Section 4: Surgical Practices
14. Surgical embolectomy
15. Bypass surgery
16. Decompressive hemicraniectomy.

Contents:
Acute kidney injury epidemiology : from recognition to intervention / Wang, Y., Fang, Y., Teng, J., Ding, X.
Acute kidney injury prevention / Chopra, T.A., Brooks, C.H., Okusa, M.D.
Renal recovery after acute kidney injury / Macedo, E., Mehta, R.L.
Pathophysiology of septic acute kidney injury / Mårtensson, J., Bellomo, R.
Biomarkers for diagnosis, prognosis and intervention in acute kidney injury / Fuhrman, D.Y., Kellum, J.A.
The acute kidney injury to chronic kidney disease transition : a potential opportunity to improve care in acute kidney injury / Palant, C., Amdur, R., Chawla, L.S.
Electronic data systems and acute kidney injury / Cheungpasitporn, W., Kashani, K.
Fluid management in acute kidney injury / Chuang, C.-L.
Multidimensional approach to adequacy of renal replacement therapy in acute kidney injury / Villa, G., Ricci, Z., Romagnoli, S., Ronco, C.
Timing of renal replacement therapy in acute kidney injury / Ostermann, M., Wald, R., Bagshaw, S.M.
Pediatric continuous renal replacement therapy / Ricci, Z., Goldstein, S.L.
Management of cardiac surgery-associated acute kidney injury / Ding, X., Xu, J., Jiang, W., Fang, Y., Teng, J.

Summary: This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis. Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.

Contents:
Part 1 Diagnosis and risk factors of AKI
Definition and epidemiology of AKI
Cause of AKI (prerenal, renal, postrenal)
Pathophysiology of AKI
Diagnosis of AKI (clinical assessment, novel biomarkers)
Risk factors for AKI development in surgery
Risk factors for AKI development in heart failure
7. Contrast-induced AKI
8. Antibiotics- and immunosuppression-related AKI
9. AKI in setting of cancer
Community-acquired AKI and hospital-acquired AKI
Part 2 Complication of AKI
11. Complication of homeostasis (mineral and acid-base)
12. Volume overload and cardiac and pulmonary complication
Part 3 Prevention and management of AKI
Prerenal and renal AKI
Postrenal AKI
AKI in intensive care medicine
Nondialytic supportive management of AKI
Renal replacement therapy in AKI
Outcomes and long-term follow-up of AKI patients
Prevention and management of pediatric AKI
Part 4 Experimental novel findings
AKI-to-CKD transition
AKI and nerve system
AKI and immune system
AKI and cytokines
Part 5 AKI and regenerative medicine
iPS cell and renal regenerative medicine
Embryonic genes and renal regenerative medicine
Xenotransplanted embryonic kidney.

Summary: The new edition of this well-received book provides a timely update of current knowledge on the biology, disease classification, and treatment of the acute leukemias - acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Throughout, the focus is on the provision of state of the art information and guidance that will meet the needs of clinicians. Chapters have been extensively revised to take into account advances in understanding and management that have been achieved over the past few years. In addition, new chapters have been included on selection of AML patients for therapy, a broader discussion of stem cell transplantation in AML, the role of immunotherapy in ALL, the approach to newly diagnosed pediatric ALL, and the diagnosis and management of BCR-ABL-like ALL. New therapies, including investigational ones, are fully covered. As progress continues in the management of acute leukemias this book will be a valuable asset for clinicians at all levels of experience.

Contents:
Part I Acute Myeloid Leukemia
Acute Myeloid Leukemia: Epidemiology and Etiology
Clinical Presentation, Diagnosis and Classification of Acute Myedloid Leukemia
Selection of Patients for Therapy
Therapy of Newly Diagnosed AML
Management of Relapsed and Refractory AML
Stem cell Transplant in AML
Investigational Therapies in AML
Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia: Epidemiology abnd Etiology
Molecular Biology and Genetics
Acute Lymphoblastic Leukemia: Clinical Presentation, Diagnosis, and Classification
Therapy of Newly Diagnosed Adult ALL
Approach to Newly Diagnosed Pediatric and AYA ALL
The Role of Immunotherapy in ALL
STem Cell Transplantation in the Treatment of ALL
The Significance of Minimal Residual Disease in Acute Lymphoblastic Leukemia
Philadelphia Chromosome
Positive Acute Lymphoblastic Leukemia
BCR-ABL-like ALL: Diagnosis and Management
Burkitt's Acute Lymphoblastic Leukema in Adults
Treatment of Lymphoblastic Lymphoma in Adults
Central Nervous System Involovment in Adult Acute Lymphocytic Leukemia
Management of Relapsed and Refractory ALL
Emergencies in Acute Lymphoblastic Leukema
Investigational Therapies in ALL.

Summary: Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies. ​

Summary: Emergency General Surgery has become a cornerstone of Acute Care Surgery over the past decade. Once the scope of community general surgeons, the growing complexity of patients with acute surgical diseases has increasingly driven their care to tertiary referral centers. The aging population confounds this problem further as these patients present with more complex comorbidities, life-threatening physiology, and progressively severe anatomic disease severity. To ensure better outcomes, the practice has evolved to focus on evidence-based practice management guidelines in order to standardize care and optimize outcomes. This text provides a comprehensive volume for any surgeon who treats patients with acute surgical diseases. The first section is a comprehensive analysis of the background of Emergency General Surgery. The goal of this section is to provide the reader background into the acute surgical practice and to introduce the reader to the important concepts discussed in the remainder of the text. The second section discuss specific acute surgical diseases. Individual chapters outline the diagnostic approach, current treatment standards, operative approaches, and expected outcomes with an emphasis on practice management guideline implementation into practice. As acute surgical diseases and surgical critical care are integral to each other, the last section will be Critical Care for the Acute Care Surgeon. These topics focus on the critical care concepts essential to surgeons who care for acute diseases. This comprehensive text is targeted to any surgeon who takes emergency calls for any of the listed diseases including community and referral general and vascular surgeons. In addition, this would be an excellent resource for all general surgery residents. Lastly, this would also serve as a resource to intensivists who care for acute surgical patients.

Contents:
History and Evolution of Emergency General Surgery
Examination of the Acute Abdomen
Development of the AAST Disease Severity Stratification System
Infectious Disease Considerations
Primer on Practice Management Guidelines
Concepts in Emergency Research (Exception from Informed Consent)
Inter-hospital Transfers of Emergency General Surgery Patients
Emergency General Surgery as a Team Sport
Small Bowel Obstruction
Large Bowel Obstruction
Abdominal Wall Hernias
Acute Cholecystitis
Appendicitis
Acute Colonic Diverticulitis
Intestinal Ischemia
Perforated Peptic Ulcer
Gastrointestinal Hemorrhage
Complications of Acute Pancreatitis
Acute and Chronic Enterocutaneous Fistula Management
Soft Tissue Infection
Perirectal Abscess
Sepsis Resuscitation
Hemorrhage Resuscitation
Ventilator Management
Nutrition Considerations
Geriatrics and End of Life Care.

Summary: "Acute Medicine offers an accessible and concise guide to the practical management of all acute medical problems likely to be encountered in the emergency department, ambulatory care centre, acute medical unit or on the wards. Reflecting the maturation of acute medicine as a separate specialty, the book is divided into common presentations, specific problems and procedures. New to the fifth edition is a chapter on bed-side ultrasonography; throughout, emphasis is placed on patient safety, and the use of flow diagrams, tables and figures ensures that key information is quickly accessible. Thoroughly revised by experts in the subject, and updated to reflect current approaches to diagnosis and management, Acute Medicine is an excellent companion for the trainee as well as an aide-mm̌oire for the more experienced physician"--Provided by publisher.

Contents:
Presentations in Acute Medicine. The critically ill patient / Marlies Ostermann, David Sprigings
Hypotension and shock / Marlies Ostermann, David Sprigings
Reduced conscious level / Simon Rinaldi
Delirium / David Sprigings
Falls in older people / Simon Conroy, Oja Pathak
Cardiac arrest in hospital / David Sprigings, John B Chambers
Acute chest pain / John B Chambers, David Sprigings
Palpitations / Sandeep Hothi, David Sprigings
Transient loss of consciousness / Sandeep Hothi, David Sprigings
Acute breathlessness / David Sprigings, John B Chambers
Acute respiratory failure / Nayia Petousi
Pleural effusion / Ioannis Psallidas
Cough and haemoptysis / Ahmed Yousuf
Neurological diagnosis in acute medicine / Simon Rinaldi
Acute headache / Simon Rinaldi
Seizures and epilepsy / Bridget MacDonald
Weakness and paralysis / Simon Rinaldi
Acute sensory symptoms / Simon Rinaldi
Loss of vision / Tristan McMullan, David Sprigings
Acute vomiting / Simon Anderson
Acute abdominal pain / Simon Anderson
Acute diarrhoea / Simon Anderson
Acute jaundice / Ben Warner, Mark Wilkinson
Ascites / Ben Warner, Mark Wilkinson
Acute kidney injury / Marlies Ostermann, David Sprigings
Acute rash / Nemesha Desai, Ruth Lamb
Urticaria and angioedema / Alexandra Croom
Acute arthritis / Kehinde Sunmboye
Acute spinal pain / Michael Canty
Acute limb pain / David Sprigings
Comprehensive geriatric assessment / Simon Conroy, Oja Pathak
Acute medical problems in pregnancy / Lucy Mackillop, Charlotte Frise
Fever on return from abroad / Nick Beeching, Mike Beadsworth
Acute medical problems in the HIV-positive patient / Mas Chaponda, Nick Beeching
Syndromes and Disorders. Sepsis / Guy Glover, Manu Shankar-Hari
Poisoning / Nigel Langford, David Sprigings
Acid-base disorders / Nick Talbot
Anaphylaxis / Alexandra Croom
Acute arrhythmias: general principles of management / David Sprigings, John B Chambers
Regular broad complex tachycardia / Michael Cooklin, David Sprigings
Irregular broad complex tachycardia / Michael Cooklin, David Sprigings
Narrow complex tachycardia / Michael Cooklin, David Sprigings
Atrial fibrillation and flutter / Michael Cooklin, David Sprigings
Bradycardia and atrioventricular block / Michael Cooklin, David Sprigings
Acute coronary syndromes (1): ST-segment elevation / Jim Newton, John B Chambers
Acute coronary syndromes (2): Non-ST-segment elevation / Jim Newton, John B Chambers
Acute pulmonary oedema / David Sprigings, John B Chambers
Acute heart failure and decompensated chronic heart failure / John B Chambers, David Sprigings
Cardiogenic shock / John B Chambers, David Sprigings
Aortic dissection and other acute aortic syndromes / John B Chambers
Heart valve disease and prosthetic heart valves / John B Chambers
Infective endocarditis / John B Chambers, John L Klein
Acute pericarditis / David Sprigings, John B Chambers
Cardiac tamponade / John B Chambers, David Sprigings
Severe hypertension / David Sprigings, John B Chambers
Deep vein thrombosis / Charlotte Masterton-Smith, Kevin O'Kane
Pulmonary embolism / Roshan Navin, Kevin O'Kane
Problems with pacemakers and other cardiac devices / Michael Cooklin, David Sprigings
Upper airway obstruction / Matthew Frise
Acute asthma / Swapna Mandal
Exacerbation of chronic obstructive pulmonary disease (COPD) / Eui-Sik Suh
Community-acquired pneumonia / Ahmed Yousuf
Hospital-acquired pneumonia / Ahmed Yousuf
Pneumothorax / Rob Hallifax
Stroke / Tony Rudd, Ajay Bhalla
Transient ischaemic attack / Ajay Bhalla, Tony Rudd
Subarachnoid haemorrhage / Michael Canty
Bacterial meningitis / David Sprigings, John L Klein
Encephalitis / David Sprigings
Spinal cord compression / Michael Canty
Guillain-Barré syndrome / Simon Rinaldi
Raised intracranial pressure / Michael Canty
Acute upper gastrointestinal bleeding / Simon Anderson, Udi Shmueli
Acute lower gastrointestinal bleeding / Sophia Savva, Andrew Dixon
Acute oesophageal disorders / Sophia Savva, Andrew Dixon
Inflammatory bowel disease flare / Sophia Savva, Andrew Dixon
Acute liver failure and decompensated chronic liver disease / Ben Warner, Mark Wilkinson
Alcoholic hepatitis / Ben Warner, Mark Wilkinson
Biliary tract disorders and acute pancreatitis / Ben Warner, Mark Wilkinson
Urinary tract infection / Carolyn Hemsley, Claire van Nispen tot Pannerden
Hypoglycaemia / Vimal Venugopal, Vito Carone, Manohara Kenchaiah
Hyperglycaemic states / Vimal Venugopal, Vito Carone, Manohara Kenchaiah
Diabetic ketoacidosis / Vimal Venugopal, Vito Carone, Manohara Kenchaiah
Hyperosmolar hyperglycaemic state / Vimal Venugopal, Vito Carone, Manohara Kenchaiah
Disorders of plasma sodium concentration / James Crane, Paul Carroll, Martin Crook
Disorders of plasma potassium concentration / Martin Crook
Disorders of plasma calcium concentration / Martin Crook
Disorders of plasma magnesium concentration / Martin Crook
Disorders of plasma phosphate concentration / Martin Crook
Acute adrenal insufficiency / James Crane, Paul Carroll
Thyrotoxic storm / James Crane, Paul Carroll
Myxoedema coma / James Crane, Paul Carroll
Pituitary apoplexy / James Crane, Paul Carroll
Paraganglioma (phaeochromocytoma) crisis / James Crane, Paul Carroll
Cellulitis and necrotizing fasciitis / David Sprigings, John Klein
Erythroderma and toxic epidermal necrolysis / Nemesha Desai, Seshi Manam
Acute gout and pseudogout / Kehinde Sunmboye
Septic arthritis / Kehinde Sunmboye, John L Klein
Acute vasculitis / Raashid Luqmani
Interpretation of full blood count and film / Claire Harrison
Pancytopenia and febrile neutropenia / Deborah Hay
Bleeding disorders / Claire Harrison
Management of anticoagulation / Catherine Hildyard
Acute painful sickle cell crisis / Jo Howard
Complications of cancer / John B Chambers, Janine Mansi
Alcohol-related problems in acute medicine / David Sprigings
Hypothermia / David Sprigings
Drowning / Francesca Garnham
Electrical injury / Francesca Garnham, David Sprigings
Palliative and end-of-life care / Louise Free
Medicolegal issues in acute medicine / Tom Lloyd, Angelique Mastihi
Techniques and Procedures in Acute Medicine. Airway management / Matthew Frise
Non-invasive ventilation / Christopher Turnbull
Ultrasonography in acute medicine / John B Chambers, Nadia Short, Luna Gargani
Reading a chest X-ray / Ambika Talwar
Central vein cannulation / Sandeep Hothi, David Sprigings
Arterial blood sampling and cannulation / David Garry
Arterial blood gases, oxygen saturation and oxygen therapy / David Sprigings
Temporary cardiac pacing / Sandeep Hothi, David Sprigings
Pericardial aspiration (pericardiocentesis) / Sandeep Hothi, David Sprigings
DC cardioversion / Sandeep Hothi, David Sprigings
Insertion of an intercostal chest drain / John Corcoran
Lumbar puncture / Kannan Nithi
Aspiration of the knee joint / Kehinde Sunmboye
Insertion of a Sengstaken-Blakemore tube / Ben Warner, Mark Wilkinson.

Summary: This book, written by a team of leading experts, provides a comprehensive overview of acute myeloid leukemia (AML), the most frequent acute leukemia in adults. The opening chapters present current knowledge of epidemiology, etiologic factors, and the pathogenesis and molecular development of AML. Detailed guidance is offered on laboratory and clinical diagnostic workup and disease classification, and the patient- and disease-related factors that determine prognosis and treatment allocation are identified. On the basis of these general considerations, initial treatments in patients considered fit for intensive treatment and in older and co-morbid patients are reviewed, and the available relapse treatment strategies, explained. For all clinical scenarios, the most recent data on the optimal use of newly approved agents in different AML subgroups are presented. Separate chapters address the treatment of acute promyelocytic leukemia, current practice of allogeneic stem cell transplantation, and special clinical situations. Finally, promising approaches in drug development, current standards and challenges in assessment of measurable residual disease, immune approaches, and ideas for innovative trial designs are considered.

Contents:
1. Epidemiology and Etiology
2. Diagnosis and Classification of AML: WHO 2016
3. The Genomic Landscape and Clonal Evolution of AML
4. Clinical Manifestation and Diagnostic Workup
5. Prognostic Factors and Treatment Allocation
6. Treatment of Acute Promyelocytic Leukemia
7. Treatment of Newly Diagnosed AML in FitPatients
8. Treatment of Newly Diagnosed AML in Unfit Patients
9. Treatment of Relapsed and Refractory AML
10. Allogeneic Stem Cell Transplantation
11. Special Clinical Scenarios
12. Future Developments.

Summary: This practical guide provides the reader with answers to important clinically relevant questions regarding the evaluation and management of acute kidney injury (AKI). All aspects of critical care nephrology are covered, from pathophysiology and diagnosis to prevention and treatment. The questions considered relate to a wide range of issues, such as: How do I diagnose AKI? How can I protect the kidney in clinical practice? How do I manage patients with AKI? When should I initiate and how do I perform renal replacement therapy (RTT)? Which type of RTT is most appropriate for my patient? Should I give specific nutrients? In addition to providing practical guidelines and treatment algorithms, the book includes calculators for continuous RRT and anticoagulant dosing. The authors are internationally renowned experts in the fields of Intensive Care Medicine and Nephrology, and all contributions are written in a clear and concise style and have been peer reviewed. Acute Nephrology for the Critical Care Physician will serve as a very useful source for intensivists, internists, anesthesiologists, and nephrologists involved in the management and treatment of critically ill patients at risk of or affected by AKI.

Contents:
1. Acute Kidney Injury (AKI): Definitions and clinical context (Z. Ricci)
2. Epidemiology of AKI (E. Hoste)
3. Pathophysiology of AKI: Ischemia/reperfusion, Sepsis/inflammation, Toxicity, Vascular (A.B.J. Groeneveld,)
4. Diagnostic work-up of the patient with suspected AKI: Oliguria, Metabolic acidosis (J. Prowle)
5. Uremic toxins (R. Vanholder)
6. The kidney and other organs/conditions: Heart, Cardiorenal syndromes, Uremic pericarditis, Lungs/Asthma renale, Liver/Hepatorenal syndrome, Gut/Uremic mucositis/GI permeability, Brain, Coagulation, Pregnancy (S. Bagshaw)
7. Biomarkers for AKI (M. Ostermann)
8. Prevention of AKI and protection of the kidney: Fluids, Vasopressors, Inotropes and vasodilators, Anti-inflammatory treatment, Antioxidants; Prevention of contrast associate nephropathy (M. Joannidis, co-authors ICM paper)
9. Timing of renal replacement therapy (RRT) in AKI (S. Bagshaw,)
10. Dosing of RRT (C.S.C. Bouman)
11. Types of RRT: Continuous vs. intermittent, Convection vs. diffusion, Predilution vs. Postdilution, SLED, Replacement fluids, Membranes, Biocompatability (L.G. Forni)
12. Anticoagulation for RRT: Heparin, Citrate, HIT (H.M. Oudemans)
13. Metabolic aspects of continuous renal replacement therapy (CRRT): Control of acidosis, Control of electrolytes, Bioenergetic gain and loss, Loss of (micro)nutrient, Nutrition (O. Joannes Boyeau)
14. CRRT: in sepsis, after cardiac surgery (P. Honore)
15. CRRT in the pediatric population (Z. Ricci)
16. Drug removal by CRRT and drug dosing in the patient on CRRT (M. Schetz)
17. CRRT for intoxications (D. Cruz)
18. How to avoid harm in the patient with AKI: summary of key points of previous chapters (H.M. Oudemans)
19. Follow-up and long-term renal outcomes of patients surviving AKI (J. Prowle).

Summary: The book provides detailed information on all major neuroemergencies, and includes a detailed checklist for practical care during the first hour of an emergency. Reinforcing the concept of quality care for better outcomes in patients with neurological diseases, the book discusses approaches to comatose patients, neurological evaluation, neuropharmacology, neuroradiology, traumatic brain and spine injury, and various other neurological disorders. The field of neuroanesthesiology and neurocritical care has expanded with the advent of newer, complex surgeries, and neurocritical care is becoming an established subspecialty of neuroscience. Neurological emergencies require special care since prevention of secondary damage to the brain is of paramount importance. A valuable resource for intensivists, neurointensivists, emergency medicine physicians, neurology and neurosurgeons and nursing professionals involved in neurocare, this book also serves as study material for participants of the two-day course on "Acute Neuro Care" designed by the Indian Society of Neuroanesthesiology and Critical Care (ISNACC).

Summary: This practical guide for trainees and advanced practice providers covers the essential management of hospitalized patients with acute neurologic conditions. Divided into five sections, this text serves as an incredibly easy-to-use, visually accessible, how-to manual that covers exactly what every responding clinician needs to know to care for the patient in front of them. The first section provides tangible guidance about how to pre-round, structure a presentation, examine neurologically ill patients, and interpret the core diagnostics obtained in many neurology patients: CT, MRI and EEG. The next three sections cover common complaints encountered in the hospital: spanning from non-vascular admissions, vascular & stroke neurology topics, and core neurocritical care principals and chief complaints. Throughout are checklists, scoring systems, pro-tips, images, helpful reminders, as well as concise summary of the pertinent literature. This is an ideal guide for medical students, neurology & neurosurgery trainees and advanced practice providers, as well as experienced professionals who want to brush up on the latest updates.

Contents:
Part One: A Comprehensive "How-To" Guide
Pre-Rounding On and Presenting Floor Patients. Pre-Rounding and Presenting NeuroICU Patients
The Coma Exam
Tips for Common Cranial Nerve Exam Findings
Stroke and Vascular Anatomy
Basics of Computed Tomography (CT)
Basics of MRI Ordering and Assessment
Understanding Transcranial Dopplers (TCDs)
Tips and Tricks for EEG Interpretation
Part Two: Vascular Neurology
Acute Ischemic Stroke First Encounter Assessment and Management
Perfusion Imaging
Ischemic Stroke: Admission Checklist
Stroke Workup Beyond the Basics
Ischemic Stroke Dissection
Ischemic Stroke - Symptomatic Carotid Stenosis "Hot Carotid" Ischemic Stroke Post Stroke Management of Anticoagulation
Selected Anti-Platelets and Anticoagulation in Stroke Prevention
Acute Management Strategies TPA and Mechanical Thrombectomy Trials
Venous Sinus Thrombosis
Posterior Reversible Vasoconstriction Syndrome (PRES) and Reversible Cerebral Vasoconstriction Syndrome (RCVS)
Part Three: Non-Vascular Inpatient Neurology
Altered Mental Status
Framework for Workup of Unknown Brain "Lesion" Approach to First-Time Seizure
Pharmacology Tips for Commonly Used AEDs Tips
Approach to Infectious Encephalitis and Meningitis
Aseptic Meningitis
Inflammatory and Autoimmune Encephalitis
Differential Diagnosis and Ordering Guide: Neuroanatomical Syndromes
Autoimmune Encephalitis Testing
Approach to New Onset Weakness
Workup of New Demyelinating Lesions
Approach to the "Dizzy" Patient
Part Four: NeuroICU
Intracranial Pressure: Theory and Management Strategies
Management of External Ventricular Catheters
Malignant Middle Cerebral Artery Infarction Intracerebral Hemorrhage Management
Intracranial Hemorrhage LandmarkTrials
Reversal of Selected Anti-Thrombotics
An In-Depth Review of Reversing Direct Factor XA-Inhibitor-Related Hemorrhages
Intracranial Hemorrhage - Management of Anticoagulation
Subarachnoid Hemorrhage Differential
Aneurysmal SAH Admission and Early Management
Subarachnoid Hemorrhage Scoring Systems
Aneurysmal SAH Daily Management Principles
Subarachnoid Hemorrhage Notable Trials
Traumatic Brain Injury.-Trials in TBI
Induced Hypothermia after Cardiac Arrest
Status Epilepticus
Continuous EEG Monitoring, Electrographic Seizures and The Ictal-Interictal Continuum
Neuromuscular Crises: ICU Management of Guillan Barr & Myasthenia Gravis
Evaluation of C-Spine Trauma
ICU Management of Spinal Cord Injuries
Management of Post-Operative Craniotomy Patients
Post-Operative Management of Cerebrovascular Patients
Preparation for Brain Death Testing
Nutrition in the NeuroICU
Hypernatremia in the NeuroICU
Hyponatremia in the NeuroICU
Pressors and Inotropes Commonly Used in the NeuroICU Seizure Prophylaxis in the NeuroICU
Venous Thromboembolism Prophylaxis in the NeuroICU
Part Five: Important References
Brainstem Anatomy NeuroICU Intravenous Fluid Compositions
Anti-Epileptic Drug Chart, For Use in Adults
Drug-Drug Interactions Common in Neuro Patients
Myasthenia Gravis: Medications to Avoid
Parkinsons Disease: Medications to Avoid.

Summary: This book is the result of a convergence of scientific information regarding mechanisms that produce acute nerve cell death in the brain. Although seemingly disparate, stroke, brain and spinal cord trauma, coma from a low serum glucose concentration (hypoglycemia), and prolonged epileptic seizures have in common the inciting factor of excitotoxicity, the activation of a specific subtype of glutamate receptor by an elevated extracellular glutamate concentration that results in an excessive influx of calcium into nerve cells. The high calcium concentration in nerve cells activates several enzymes that are responsible for degradation of cytoplasmic proteins and cleavage of nuclear DNA, resulting in nerve cell death. The high calcium concentration also interferes with mitochondrial respiration, with the resultant production of free radicals that damage cellular membranes and nuclear DNA. Understanding the biochemical pathways that produce nerve cell death is the first step toward devising an effective neuroprotective strategy, the ultimate goal.

Contents:
General considerations
Traumatic brain injury
Focal cerebral ischemia
Transient global cerebral ischemia
Hypoglycemic neuronal injury
Seizure-induced neuronal death.

Summary: This book provides recommendations for evaluation and therapy in the area of acute pediatric neurology; these are presented didactically with frequent use of illustrations and algorithms. Chapters in the first part of the book discuss presenting symptoms of acute neurological conditions. The second part of the book covers major areas of acute pediatric neurology and each of these chapters has three key elements: description of presenting symptoms; recommended assessments; and recommended interventions. Acute Pediatric Neurology provides an accessible, clinically focused guide to assist physicians in the emergency ward or intensive care unit in decisions on diagnosis and therapeutic interventions in all major acute pediatric neurological diseases.

Contents:
Part 1: Acute Neurological Symptoms
Unconsciousness, Coma, and Death by Neurological Criteria
Seizures
Acute Headache
Acute Disturbance of Motor Function
Acute Disturbance of Vision
Dizziness and Vertigo
Acute Changes of Behavior and Memory
Part 2: Management of Acute Neurological Conditions
Ischemic and Hypoxic Insults: Near Drowning, Asphyxia, Carbon Monoxide Poisoning
Neurometabolic Crisis
Approach to childhood-onset Muscle Cramps, Exercise Intolerance and Recurrent Myoglobinuria
Management of Seizures and Status Epilepticus
Management of Increased Intracranial Pressure
Management of Migraine and Other Headaches
Central Nervous System Infections (bacteria and parasites)
Management of Acute Neuromuscular Disorders
Stroke and Cerebrovascular Diseases
Viral Infections, Autoimmune and Demyelinating Conditions of the Central Nervous System
Spasticity, Dystonia, and Other Movement Disorders: A Comprehensive Treatment Guide
Acute Pain.

Contents:
History of APL
Molecular Targets of Treatment in APL
The Leukemic Stem Cell
The Molecular Genetics of APL
APL Coagulopathy
Early Death in APL
Prognostic Factors in APL
First-line therapy for APL: Chemotherapy-based approach
First-line Therapy: ATRA-ATO/Reduced Chemotherapy Approach
Cure of APL without Chemotherapy
Minimal Residual Disease in APL
Treatment of refractory and relapsed APL
Hematopoietic Stem Cell Transplantation in APL
APL in Children
Management of APL in the Elderly
Special Situations in APL
APL in Developing Countries: A Chemotherapy-Based Approach
APL in Developing Countries: ATO based Approach
Therapy-Related APL
Rare Acute Leukemia Variants involving Retinoic Acid Receptor Genes
Management of Treatment-Related Complications in APL.

Summary: This book covers all clinical aspects of acute respiratory distress syndrome (ARDS), from definition to treatment, focusing on the more recent recommendations and evidence-based medicine. The addressed topics are the various ventilation strategies, the impact of prone positioning, the use of partial and total extracorporeal support, the value of vasodilators, the weaning from mechanical ventilation, the pharmacological interventions, noninvasive ventilation, and the strategies using anti-inflammatory agents and stem cells. Furthermore, different related topics are also discussed, such as lung imaging, sedation, metabolic support, and hemodynamic instability. A concluding chapter specifically addresses ARDS in children. This up-to-date volume, written by experts in the field, will be of value for all health care practitioners seeking state of the art on the management of patients with this complex syndrome.

Summary: Divided into thirteen chapters, this book provides a wealth of research-oriented findings and practical guidance, ranging from the definition, epidemiology and pathophysiology, to the diagnosis and management of the disease. Although acute respiratory distress syndrome (ARDS) is defined by the acute onset of noncardiogenic pulmonary edema, hypoxemia and the need for mechanical ventilation, it is a heterogeneous disease entity, which makes it difficult to develop specific therapies. Treatment tends to focus on lung-protective ventilation, and no specific pharmacotherapies have been identified. All chapters were written by respected experts in the field, and summarize the latest trends, share recent research findings, and outline future prospects. Specific chapters are devoted to novel, promising diagnostic approaches, such as microRNA, which may improve our ability to identify early ARDS or at-risk patients. In addition, a dedicated chapter explores cell-based therapies and regenerative medicine, which offer potential therapeutic options. Acute Respiratory Distress Syndrome - Advances in Diagnostic Tools and Disease Management offers a valuable reference guide not only for young physicians and trainees, but also for experienced or teaching physicians, medical educators, and basic researchers. Readers will find the latest information on ARDS and come to understand the current challenges, encouraging them to further advance the diagnosis, treatment and clinical research on this disease.

Summary: Acute Rheumatic Fever and Rheumatic Heart Disease is a concise, yet comprehensive, clinical resource highlighting must-know information on rheumatic heart disease and acute rheumatic fever from a global perspective. Covering the major issues dominating the field, this practical resource presents sufficient detail for a deep and thorough understanding of the latest treatment options, potential complications, and disease management strategies to improve patient outcomes. Divided into four distinct sections for ease of navigation: Acute Rheumatic Fever, Rheumatic Heart Disease, Population-Based Strategies for Disease Control, and Acute and Emergency Presentations. International editors and chapter authors ensure a truly global perspective. Covers all clinical aspects, including epidemiology, pathophysiology, clinical features, diagnosis, management, and treatment. Includes key topics on population-based measures for disease control for effective primary, secondary, and tertiary prevention. Consolidates today's available information and guidance into a single, convenient resource.

Contents:
Burden, cost, and epidemiology of acute rheumatic fever and rheumatic heart disease
Pathogenesis of acute rheumatic fever
Clinical evaluation and diagnosis of acute rheumatic fever
Management of acute rheumatic fever
Clinical evaluation and diagnosis of rheumatic heart disease
Medical management of rheumatic heart disease
Catheter-based investigation and treatment of rheumatic heart disease
Surgical management of rheumatic heart disease
Rheumatic heart disease in pregnancy
Primordial and primary prevention prevention of ARF and RHD
Secondary prevention of ARF and RHD
Control programmes, registries, and access to care
Rheumatic heart disease screening
Group A streptococcal vaccine
Advocacy and education
Acute complications and Emergencies of ARF and RHD.

Summary: This book provides clear guidance on how to manage a wide range of side effects frequently encountered when treating patients with radiation therapy. For each potential side effect, incidence, mechanism, symptoms, and grading are carefully described. All aspects of management are addressed, drawing on the latest available evidence and highlighting key details of importance in clinical routine. The introduction of new radiation therapy techniques such as 3D conformal radiation therapy, intensity-modulated radiation therapy, and image-guided radiation therapy has reduced normal tissue doses and, accordingly, treatment complications. Nevertheless, a significant percentage of patients still experience acute side effects, in part because the threshold doses for these toxicities are typically lower than those for late effects. Acute toxicities may lead to interruption of treatment and be associated with an increase in late damage. A swift and effective response is therefore essential. This book will enable the reader to provide effective care for each side effect, thereby improving patient compliance with treatment and treatment outcomes.

Summary: You have just encountered a possible stroke patient. You ask yourself: what should I do first? How do I know it is a stroke? Is it too late to reverse the damage? This book provides integral assistance in answering these critical questions. All content is arranged in chronological order, covering all considerations in assessing and treating patients in the emergency room, stroke unit, and rehabilitation facilities. This new edition offers readers the latest information on stroke treatment, and features brand new chapters on stroke radiology, endovascular therapy, the uncommon causes of stroke, cerebral venous thrombosis, stroke prevention, and the transition to outpatient care. The comprehensive set of appendices contains useful reference information, including dosage algorithms, conversion factors, and stroke scales.

Contents:
Stroke in the emergency department
What to do first
Ischemic stroke
Stroke radiology
Intravenous thrombolysis
Endovascular therapy (ET)
Neurological deterioration in acute ischemic stroke
Ischemic stroke etiology and secondary prevention
Transient ischemic attack (TIA)
Less common causes of stroke
Cerebral venous sinus thrombosis
Intracerebral hemorrhage (ICH)
Subarachnoid hemorrhage (SAH)
Organization of stroke care
Stroke rehabilitation
Transition to outpatient stroke care.

Summary: This book contains a compilation of the revolution of mechanical thrombectomy (MT) in the treatment of strokes. The initial chapters summarize information about the best medical management of acute ischemic stroke, imaging modalities and patient selection for MT. The book then focuses on the nuances of MT, providing detailed information about the best approaches for anesthesia during MT, access, intra-arterial thrombolysis, recent devices and catheters and technical pitfalls of MT. A specific chapter is dedicated to MT in the venous system. This is followed by a chapter about the most common complications of MT and post-procedural care of these patients. The last chapter covers different aspects of acute stroke care and MT in the developing world. The authors of this book comprise of a multidisciplinary group of world experts in the field and were encouraged to include teaching cases to deliver a book with a practical approach. Acute Stroke Management in the Era of Thrombectomy is intended for all healthcare providers who care for patients with stroke; with special emphasis for the proceduralists who are interested in technical tips to improve outcomes and minimize complications.

Contents:
Best Medical Management for Acute Ischemic Stroke
Imaging of Acute Ischemic Stroke
Indications for Mechanical Thrombectomy
Anesthesia During Endovascular Treatment of Acute Ischemic Stroke
Arterial Access and Intermediate Catheters: Procedural and Technical Considerations
Intra-arterial Thrombolytics for Treatment of Acute Ischemic Stroke
Mechanical Thrombectomy: Emerging Devices and Technologies
Mechanical Thrombectomy: Techniques and Hybrid Approaches for Recanalization
Acute Stenting During Acute Ischemic Stroke
Tandem Occlusion Causing Acute Ischemic Stroke
Mechanical Thrombectomy in Distal Vessels: M2s and Beyond
Thrombectomy of the Posterior Circulation: Tips and Tricks
Thrombectomy in the Venous System: Approaches and Techniques
Complications During Mechanical Thrombectomy: Pitfalls and Bailouts
Post-operative Care After Mechanical Thrombectomy
Stroke-Care and Mechanical Thrombectomy in Developing Countries.

Summary: This book aims to familiarize readers with the most common acute surgery topics encountered in clinical practice and is unique in its use of infographics. It will be used in clinical rotations in surgery as a supplement to the knowledge gained, and will also provide instructors with a complementary tool, offering a wide-ranging guide to general aspects of acute surgery, with some hints on gynecologic and urologic emergencies. The book is intended to provide medical students and junior residents in medicine or surgery with a comprehensive and up-to-date overview of the most relevant operative techniques.

Contents:
Preoperative Labs And Tests
Preoperative Cardiac Evaluation
Preoperative Pulmonary Evaluation
The Abc's of Medical Imaging
Appendicitis
Acute Cholecystopathy
Acute Pancreatitis
Acute Diverticulitis
Small Bowel Obstruction
Large Bowel Obstruction (Lbo)
Clostridioides Difficile Colitis
Upper Gastroitestinal Bleeding
Lower Gastrointestinal Bleeding
Variceal Bleeding
Caustic Ingestion
Neutropenic Enterocolitis
Acute Mesenteric Ischemia
Ruptured Abdominal Aortic Aneurysm
Aortic Dissection
Peripheral Arterial Embolism
Hypercoagulability
Bleeding Disorders.

Contents:
Brief introduction to the history of anti-doping / Ljungqvist, A.
The development of the world anti-doping code / Young, R.
Is the fight against doping in sport a legal minefield like any other? / Haas, U.
How will the legal and sport environment influence a future code? / Niggli, O.
Structure and development of the list of prohibited substances and methods / Kinahan, A.; Budgett, R.; Mazzoni, I.
Therapeutic use exemptions / Gerrard, D.; Pipe, A.
Challenges in modern anti-doping analytical science / Ayotte, C.; Miller, J.; Thevis, M.
Achievements and challenges in anti-doping research / Bowers, L.D.; Bigard, X.
Gene and cell doping : the new frontier : beyond myth or reality / Neuberger, E.W.I.; Simon, P.
The athlete biological passport : how to personalize anti-doping testing across an athlete's career? / Robinson, N.; Sottas, P.-E.; Schumacher, Y.O.
Next generation "omic" approaches in the "fight" against blood doping / Wang, G.; Karanikolou, A. ; Verdouka, I.; Friedmann, T.; Pitsiladis, Y.
Integration of the forensic dimension into anti-doping strategies / Marclay, F.; Saugy, M.
How to develop intelligence gathering in efficient and practical anti-doping activities / Holz, M; Robertson, J.
Education in anti-doping: the art of self-imposed constraints / Loland, S.
Can we better integrate the role of anti-doping in sports and society? : a psychological approach to contemporary value-based prevention / Petróczi, A. ; Norman, P.; Brueckner, S.
Sport, society, and anti-doping policy : an ethical overview / Bloodworth, A.J.; McNamee, M.
A moral foundation for anti-doping : how far have we progressed? where are the limits? / Murray, T.H.
Conclusion and perspectives / Howman, D.

Contents:
Accessible Routes
Site Elements
Vertical Access
Architectural Elements
Restrooms & Bathing Facilities
Other Elements
A Word or Two on Existing Projects
Innovative Ideas on Access World-Wide.

Summary: "This clinically oriented book gives dental practitioners and students a hands-on guide to incorporating dental implants into their practices. Taking a clear and concise approach to the subject, the book offers basic information on all aspects of dental implants. Topics covered encompass the pros and cons of implants, patient factors, clinical considerations to success and failure, and implant restoration. Photographs, radiographs, and illustrations support the text, demonstrating the concepts discussed. The ADA Practical Guide to Dental Implants starts with a brief history of the subject then examines the clinical and economic considerations for implants. Patient factors, including systemic, oral, and periodontal health, diet, age, gender, and more are discussed. The book also looks at the experience of the clinician, followed by clinical considerations such as case planning, implant design, surgical techniques, antibiotics, and more. The last chapters cover post-surgical follow-up and the many factors that lead to a successful outcome. The ADA Practical Guide to Dental Implants is a useful introduction and guide to dental implants for any practitioner interested in incorporating implants into clinical practice"-- Provided by publisher.

Contents:
Why dental implants
A brief history of dental implants
Design of Implants
Patient factors
Patient consults
Treatment planning and Evaluating implant sites
Implant scenarios
Implant surgery: simple healed sites
Bone grafting
Guided surgery
Immediate implant placement: complicated immediate sites
Full arch cases
Screw-retention vs. Cement-retention of restorations
Restoring dental implants
Dental implant failures
Economics of dental implants
Maintaining dental implants.

Contents:
The extraoral and intraoral soft tissue head and neck screening examination
Soft tissue head and neck pathology description and documentation
Common oral soft tissue lesions
Differential diagnosis of common oral soft tissue lesions
Guidelines for observation and/or referral of patients lesions
The art and science of biopsy and cytology
Sample patient histories and discussion.

Contents:
Ch. 1. Approach to the patient with neurologic disease
Ch. 2. Imaging, electrophysiologic, and laboratory techniques for neurologic diagnosis
Ch. 3. Motor paralysis
Ch. 5. Ataxia and disorders of cerebellar function
Ch. 6. Tremor, myoclonus, focal dystonias, and tics
Ch. 7. Disorders of stance and gait
Ch. 10. Headache and other craniofacial pains
Ch. 11. Pain i n the back, neck, and extreities
Ch. 12. Disorders of smell and taste
Ch. 13. Disturbances of vision
Ch. 14. Disorders of ocular movement and pupillary function
Ch. 15. Deafness, dizziness, and disorders of equilibrium
Ch. 16. Epilepsy and other seizure disorders
Ch. 17. Coma and related disorders of consciousness
Ch. 18. Faintness and syncope
Ch. 19. Sleep and its abnormalities
Ch. 20. Delirium and other acute confusional states.

Summary: "The definitive text on the full spectrum of neurology presented in full color and better than ever! Long considered the field's gold-standard text, Adams and Victor's Principles of Neurology provides the very latest treatment and management strategies needed to confidently handle both common and rare neurologic conditions. Presented in full color, this classic resource meets the needs of the seasoned professional or the aspiring clinician, and has been hailed as the most detailed, thorough, and authoritative text on the subject. Reviewers have favorably compared the book's consistent, single voice to consulting with an experienced senior colleague. The latest scientific research is included in just the right amount of detail to serve as a clinical reference or a starting point for additional learning. The text is logically divided into six sections: The Clinical Method of Neurology; Cardinal Manifestations of Neurologic Disease; Growth and Development of the Nervous System in the Neurology of Aging; Major Categories of Neurologic Diseases; Diseases of the Spinal Cord, Peripheral Nerve, and Muscle; Psychiatric Disorders"-- Provided by publisher. "The wise application of science, evidence from trials, and the traditional virtues of the neurological history and examination are the main purpose of this edition of Principles of Neurology"-- Provided by publisher.

Contents:
PART 1: THE CLINICAL METHOD OF NEUROLOGY
Chapter 1: Approach to the Patient With Neurologic Disease
Chapter 2: Diagnostic Testing in Neurologic Disease
PART 2: CARDINAL MANIFESTATIONS OF NEUROLOGIC DISEASE
Part 2: Cardinal Manifestations of Neurologic Disease: Introduction
Section 1: Disorders of Motility
Section 1: Disorders of Motility: Introduction
Chapter 3: Paralysis and Weakness
Chapter 4: Disorders of Movement and Posture
Chapter 5: Ataxia and Disorders of Cerebellar Function
Chapter 6: Disorders of Stance and Gait
Section 2: Pain and Disorders of Somatic Sensation
Section 2: Pain and Disorders of Somatic Sensation: Introduction
Chapter 7: Pain
Chapter 8: Disorders of Non-Painful Somatic Sensation
Chapter 9: Headache and Other Craniofacial Pains
Chapter 10: Pain in the Back, Neck, and Extremities
Section 3: Disorders of the Special Senses
Section 3: Disorders of the Special Senses: Introduction
Chapter 11: Disorders of Smell and Taste
Chapter 12: Disturbances of Vision
Chapter 13: Disorders of Ocular Movement and Pupillary Function
Chapter 14: Deafness, Dizziness, and Disorders of Equilibrium
Section 4: Epilepsy and Disorders of Consciousness
Chapter 15: Epilepsy and Other Seizure Disorders
Chapter 16: Coma and Related Disorders of Consciousness
Chapter 17: Faintness and Syncope
Chapter 18: Sleep and Its Abnormalities
Section 5: Derangements of Intellect, Behavior, and Language Caused by Diffuse and Focal Cerebral Disease
Section 5: Derangements of Intellect, Behavior, and Language Caused by Diffuse and Focal Cerebral Disease: Introduction
Chapter 19: Delirium and Other Acute Confusional States
Chapter 20: Dementia, the Amnesic Syndrome, and the Neurology of Intelligence and Memory
Chapter 21: Neurologic Disorders Caused by Lesions in Specific Parts of the Cerebrum
Chapter 22: Disorders of Speech and Language
Section 6: Disorders of Energy, Mood, and Autonomic and Endocrine Functions
Chapter 23: Fatigue, Asthenia, Anxiety, and Depression
Chapter 24: The Limbic Lobes and the Neurology of Emotion
Chapter 25: Disorders of the Autonomic Nervous System, Respiration, and Swallowing
Chapter 26: The Hypothalamus and Neuroendocrine Disorders
PART 3: GROWTH AND DEVELOPMENT OF THE NERVOUS SYSTEM AND THE NEUROLOGY OF AGING
Chapter 27: Normal Development and Deviations in Development of the Nervous System
Chapter 28: The Neurology of Aging
PART 4: MAJOR CATEGORIES OF NEUROLOGIC DISEASE
Chapter 29: Disturbances of Cerebrospinal Fluid, Including Hydrocephalus, Pseudotumor Cerebri, and Low-Pressure Syndromes
Chapter 30: Intracranial Neoplasms and Paraneoplastic Disorders
Chapter 31: Bacterial, Fungal, Spirochetal, and Parasitic Infections of the Nervous System
Chapter 32: Viral Infections of the Nervous System and Prion Diseases
Chapter 33: Stroke and Cerebrovascular Diseases
Chapter 34: Craniocerebral Trauma
Chapter 35: Multiple Sclerosis and Other Inflammatory Demyelinating Diseases
Chapter 36: Inherited Metabolic Diseases of the Nervous System
Chapter 37: Developmental Diseases of the Nervous System
Chapter 38: Degenerative Diseases of the Nervous System
Chapter 39: The Acquired Metabolic Disorders of the Nervous System
Chapter 40: Diseases of the Nervous System Caused by Nutritional Deficiency
Chapter 41: Disorders of the Nervous System Caused by Alcohol, Drugs, Toxins, and Chemical Agents
PART 5: DISEASES OF SPINAL CORD, PERIPHERAL NERVE, AND MUSCLE
Chapter 42: Diseases of the Spinal Cord
Chapter 43: Diseases of the Peripheral Nerves
Chapter 44: Diseases of the Cranial Nerves
Chapter 45: Diseases of Muscle
Chapter 46: Disorders of the Neuromuscular Junction, Myotonias, and Persistent Muscle Fiber Activity
PART 6: PSYCHIATRIC DISORDERS
Chapter 47: Anxiety Disorders, Hysteria, and Personality Disorders
Chapter 48: Depression and Bipolar Disease
Chapter 49: Schizophrenia, Delusional, and Paranoid States.

Summary: "Adams and Victor’s Principles of Neurology provides up to date treatment and management strategies needed to confidently handle both common and rare neurologic conditions. Presented in full color, this enduring resource meets the needs of today’s aspiring clinician or seasoned professional, and has been hailed as the most detailed, thorough, and authoritative text on the subject"-- Publisher's description.

Contents:
Part 1: The clinical method of neurology. Approach to the patient with neurologic disease
Diagnostic testing in neurologic disease
Part 2: Cardinal manifestations of neurologic disease. Section 1: Disorders of motility. Paralysis and weakness
Disorders of movement and posture
Ataxia and disorders of cerebellar function
Disorders of stance and gait
Section 2: Pain and disorders of somatic sensation. Pain
Disorders of non-painful somatic sensation
Headache and other craniofacial pains
Pain in the back, neck, and extremities
Section 3: Disorders of the special senses. Disorders of smell and taste
Disturbances of vision
Disorders of ocular movement and pupillary function
Deafness, dizziness, and disorders of equilibrium
Section 4: Epilepsy and disorders of consciousness. Epilepsy and other seizure disorders
Coma and related disorders of consciousness
Faintness and syncope
Sleep and its abnormalities
Section 5: Derangements of intellect, behavior, and language caused by diffuse and focal cerebral disease. Acute confusional states
Dementia, the amnesic syndrome, and the neurology of intelligence and memory
Neurologic disorders caused by lesions in specific parts of the cerebrum
Disorders of speech and language
Section 6: Disorders of energy, mood, and autonomic and endocrine functions. Fatigue, asthenia, anxiety, and depression
The limbic lobes and the neurology of emotion
Disorders of the autonomic nervous system, respiration, and swallowing
The hypothalamus and neuroendocrine disorders
Part 3: Growth and development of the nervous system and the neurology of aging. Normal development and deviations in development of the nervous system
The neurology of aging
Part 4: Major categories of neurologic disease. Disturbances of cerebrospinal fluid, including hydrocephalus, pseudotumor cerebri, and low-pressure syndromes
Intracranial neoplasms and paraneoplastic disorders
Bacterial, fungal, spirochetal, and parasitic infections of the nervous system
Viral infections of the nervous system and prion diseases
Stroke and cerebrovascular diseases
Craniocerebral trauma
Multiple sclerosis and other neuroimmunologic disorders
Inherited metabolic diseases of the nervous system
Developmental diseases of the nervous system
Degenerative diseases of the nervous system
The acquired metabolic disorders of the nervous system
Diseases of the nervous system caused by nutritional deficiency
Disorders of the nervous system caused by alcohol, drugs, toxins, and chemical agents
Part 5: Diseases of spinal cord, peripheral nerve, and muscle. Diseases of the spinal cord
Diseases of the peripheral nerves
Diseases of the cranial nerves
Diseases of muscle
Disorders of the neuromuscular junction, myotonias, and disorders of persistent muscle fiber activity
Part 6: Psychiatric disorders. Anxiety, "functional" and personality disorders
Depression and bipolar disorder
Psychosis, schizophrenia, delusional, and paranoid states.