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- Bookedited by Alan F. Schatzberg, Charles B. Nemeroff.Summary: "The American Psychiatric Association Publishing Textbook of Psychopharmacology is an indispensable and comprehensive resource for clinicians and trainees who prescribe psychotropic medications. Updated to reflect the new DSM-5 classification, this revised Fifth Edition maintains the user-friendly structure of its predecessors while offering in-depth coverage of the latest research in pharmacological principles, classes of drugs, and psychiatric disorders. Introductory chapters provide a theoretical grounding in clinical applications, with topics ranging from neurotransmitters to brain imaging in psychopharmacology. The bulk of the book is devoted to various classes of drugs, including antidepressants, anxiolytics, antipsychotics, mood stabilizers, and other agents, with each class divided into chapters on specific drugs -- either new or revised to include the latest findings and trends. Finally, the section on psychopharmacological treatment addresses evidence-based principles of clinical care for the full spectrum of mental disorders and conditions -- from depression to chronic pain -- as well as for specific populations and circumstances -- from children and adolescents to psychiatric emergencies -- offering information on topics such as medication selection, combination and maintenance dosing regimens, monitoring and management of side effects, and strategies for optimizing treatment response. The book's beneficial features are many: * The section on principles of pharmacology has been revised and reorganized to incorporate recent discoveries from the fields of neurobiology, genetics, brain imaging, and epidemiology.* History and discovery, structure--activity relationships, pharmacological profiles, pharmacokinetics and disposition, mechanisms of action, indications and efficacy, side effects and toxicology, and drug--drug interactions are addressed for each agent. This consistent structure places the desired information at the clinician's fingertips and facilitates study for trainees.* Coverage of drugs approved since the last edition is thorough, encompassing new antidepressants (e.g., vortioxetine), new antipsychotics (e.g., cariprazine), and agents on the clinical horizon (e.g., ketamine).* More than 180 tables and graphs present critically important data in an accessible way. A work of uncommon scientific rigor and clinical utility, The American Psychiatric Association Publishing Textbook of Psychopharmacology provides state-of-the-art information on both the principles and the practice of psychopharmacological treatment of psychiatric disorders."--Publisher's description.
Contents:
Part I: Principles of pharmacology. Basic principles of molecular biology and genomics
Neurotransmitters and receptors in psychiatric disorders
Genetics and genomics
Psychoneuroendocrinology
Brain–immune system interactions
Principles of pharmacokinetics and pharmacodynamics
Brain imaging in psychopharmacology
Part II: Classes of psychiatric treatments: antidepressants and anxiolytics. Monoamine oxidase inhibitors
Tricyclic and tetracyclic drugs
Fluoxetine
Sertraline
Paroxetine
Fluvoxamine
Citalopram and escitalopram
Trazodone and nefazodone
Vortioxetine
Mirtazapine
Bupropion
Venlafaxine and desvenlafaxine
Duloxetine, milnacipran, and levomilnacipran
Ketamine
Benzodiazepines
Buspirone
Antipsychotics. Classic antipsychotic medications
Clozapine
Olanzapine
Quetiapine
Risperidone and paliperidone
Aripiprazole and brexpiprazole
Ziprasidone
Asenapine
Iloperidone
Lurasidone
Cariprazine
Drugs to treat extrapyramidal side effects
Drugs for treatment of bipolar disorder. Lithium
Valproate
Carbamazepine, oxcarbazepine, and licarbazepine
Gabapentin and pregabalin
Lamotrigine
Topiramate
Other agents. Agents for cognitive disorders
Sedative-hypnotics
Psychostimulants and wakefulness-promoting agents
Electroconvulsive therapy and other neuromodulation therapies
Part III: Psychopharmacological treatment. Treatment of depression
Treatment of bipolar disorder
Treatment of anxiety and related disorders
Treatment of schizophrenia
Treatment of substance-related disorders
Treatment of personality disorders
Treatment of eating disorders
Treatment of insomnia
Treatment of chronic pain
Treatment of child and adolescent disorders
Treatment during late life
Psychopharmacology during pregnancy and lactation
Treatment of psychiatric emergencies
Treatment of agitation and aggression in the elderly - Bookedited by Alan F. Schatzberg, Charles B. Nemeroff.Summary: "The American Psychiatric Association Publishing Textbook of Psychopharmacology is an indispensable and comprehensive resource for clinicians and trainees who prescribe psychotropic medications. Updated to reflect the new DSM-5 classification, this revised Fifth Edition maintains the user-friendly structure of its predecessors while offering in-depth coverage of the latest research in pharmacological principles, classes of drugs, and psychiatric disorders. Introductory chapters provide a theoretical grounding in clinical applications, with topics ranging from neurotransmitters to brain imaging in psychopharmacology. The bulk of the book is devoted to various classes of drugs, including antidepressants, anxiolytics, antipsychotics, mood stabilizers, and other agents, with each class divided into chapters on specific drugs -- either new or revised to include the latest findings and trends. Finally, the section on psychopharmacological treatment addresses evidence-based principles of clinical care for the full spectrum of mental disorders and conditions -- from depression to chronic pain -- as well as for specific populations and circumstances -- from children and adolescents to psychiatric emergencies -- offering information on topics such as medication selection, combination and maintenance dosing regimens, monitoring and management of side effects, and strategies for optimizing treatment response. The book's beneficial features are many: * The section on principles of pharmacology has been revised and reorganized to incorporate recent discoveries from the fields of neurobiology, genetics, brain imaging, and epidemiology.* History and discovery, structure--activity relationships, pharmacological profiles, pharmacokinetics and disposition, mechanisms of action, indications and efficacy, side effects and toxicology, and drug--drug interactions are addressed for each agent. This consistent structure places the desired information at the clinician's fingertips and facilitates study for trainees.* Coverage of drugs approved since the last edition is thorough, encompassing new antidepressants (e.g., vortioxetine), new antipsychotics (e.g., cariprazine), and agents on the clinical horizon (e.g., ketamine).* More than 180 tables and graphs present critically important data in an accessible way. A work of uncommon scientific rigor and clinical utility, The American Psychiatric Association Publishing Textbook of Psychopharmacology provides state-of-the-art information on both the principles and the practice of psychopharmacological treatment of psychiatric disorders."--Publisher's description.
Contents:
Part I: Principles of pharmacology. Basic principles of molecular biology and genomics
Neurotransmitters and receptors in psychiatric disorders
Genetics and genomics
Psychoneuroendocrinology
Brain–immune system interactions
Principles of pharmacokinetics and pharmacodynamics
Brain imaging in psychopharmacology
Part II: Classes of psychiatric treatments: antidepressants and anxiolytics. Monoamine oxidase inhibitors
Tricyclic and tetracyclic drugs
Fluoxetine
Sertraline
Paroxetine
Fluvoxamine
Citalopram and escitalopram
Trazodone and nefazodone
Vortioxetine
Mirtazapine
Bupropion
Venlafaxine and desvenlafaxine
Duloxetine, milnacipran, and levomilnacipran
Ketamine
Benzodiazepines
Buspirone
Antipsychotics. Classic antipsychotic medications
Clozapine
Olanzapine
Quetiapine
Risperidone and paliperidone
Aripiprazole and brexpiprazole
Ziprasidone
Asenapine
Iloperidone
Lurasidone
Cariprazine
Drugs to treat extrapyramidal side effects
Drugs for treatment of bipolar disorder. Lithium
Valproate
Carbamazepine, oxcarbazepine, and licarbazepine
Gabapentin and pregabalin
Lamotrigine
Topiramate
Other agents. Agents for cognitive disorders
Sedative-hypnotics
Psychostimulants and wakefulness-promoting agents
Electroconvulsive therapy and other neuromodulation therapies
Part III: Psychopharmacological treatment. Treatment of depression
Treatment of bipolar disorder
Treatment of anxiety and related disorders
Treatment of schizophrenia
Treatment of substance-related disorders
Treatment of personality disorders
Treatment of eating disorders
Treatment of insomnia
Treatment of chronic pain
Treatment of child and adolescent disorders
Treatment during late life
Psychopharmacology during pregnancy and lactation
Treatment of psychiatric emergencies
Treatment of agitation and aggression in the elderly