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  • Book
    Alisa G. Woods, Costel C. Darie, editors.
    Summary: "This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine"--Publisher's description.

    Contents:
    Mass spectrometry for proteomics-based investigation / Alisa G. Woods, Izabela Sokolowska, Armand G. Ngounou Wetie,Kelly Wormwood, Roshanak Aslebagh, Sapan Patel, and Costel C. Darie
    MALDI profiling and applications in medicine / Ed Dudley
    Simplifying the proteome: analytical strategies for improving peak capacity / Lee A. Gethings and Joanne B. Connolly
    Quantitative shotgun proteomics with data-independent acquisition and traveling wave ion mobility spectrometry: a versatile tool in the life sciences / Lewis M. Brown
    Stable isotope labeling by amino acids in cell culture (SILAC) for quantitative proteomics / Esthelle Hoedt, Guoan Zhang, and Thomas A. Neubert
    Utility of computational structural biology in mass spectrometry / Urmi Roy, Alisa G. Woods, Izabela Sokolowska, and Costel C. Darie
    Affinity-mass spectrometry approaches for elucidating structures and interactions of protein-ligand complexes / Brînduşa Alina Petre
    Neurological analyses: focus on gangliosides and mass spectrometry / Alina D. Zamfir
    Mass spectrometric analysis of post-translational modifications (PTMs) and protein-protein interactions (PPIs) / Armand G. Ngounou Wetie, Alisa G. Woods, and Costel C. Darie
    Applications for mass spectrometry in the study of ion channel structure and function / Damien S.K. Samways
    A mass spectrometry view of stable and transient protein interactions / Hanna G. Budayeva and Ileana M. Cristea
    Mass spectrometry-based tissue imaging of small molecules / Carly N. Ferguson, Joseph W.M. Fowler, Jonathan F. Waxer, Richard A. Gatti, and Joseph A. Loo
    Redox proteomics: from bench to bedside / Karina Ckless
    Analysis of fluorinated proteins by mass spectrometry / Linda A. Luck
    Mass spectrometry for proteomics-based investigation using the zebrafish vertebrate model system / Reshica Baral, Armand G. Ngounou Wetie, Costel C. Darie, and Kenneth N. Wallace
    Mass spectrometry-based biomarkers in drug development / Ronald A. Miller and Daniel S. Spellman
    Detection of biomedically relevant stilbenes from wines by mass spectrometry / Veronica Andrei, Armand G. Ngounou Wetie, Iuliana Mihai, Costel C. Darie, and Alina Vasilescu
    Mass spectrometric DNA adduct quantification by multiple reaction monitoring and its future use for the molecular epidemiology of cancer / Bernhard H. Monien
    Using breast milk to assess breast cancer risk: the role of mass spectrometry-based proteomics / Sallie S. Schneider, Roshanak Aslebagh, Armand G. Ngounou Wetie, Susan R. Sturgeon, Costel C. Darie, and Kathleen F. Arcaro
    Cancer secretomes and their place in supplementing other hallmarks of cancer / Sapan Patel, Armand G. Ngounou Wetie, Costel C. Darie, and Bayard D. Clarkson
    Thiostrepton, a natural compound that triggers heat shock response and apoptosis in human cancer cells: a proteomics investigation / Cristinel Sandu, Armand G. Ngounou Wetie, Costel C. Darie, and Hermann Steller
    Using proteomics to unravel the mysterious steps of the HBV-life-cycle / Norica Branza-Nichita, Catalina Petrareanu, Catalin Lazar, Izabela Sokolowska, and Costel C. Darie
    Oxidative stress and antibiotic resistance in bacterial pathogens: state of the art, methodologies, and future trends / Mouna Marrakchi, Xiaobo Liu, and Silvana Andreescu
    Proteomic approaches to dissect neuronal signaling pathways / Heather L. Bowling and Katrin Deinhardt
    Investigating a Novel Protein Using Mass Spectrometry: The Example of Tumor Differentiation Factor (TDF) / Alisa G. Woods, Izabela Sokolowska, Katrin Deinhardt, and Costel C. Darie
    Mass spectrometry for the study of autism and neurodevelopmental disorders / Armand G. Ngounou Wetie, Robert M. Dekroon, Mihaela Mocanu, Jeanne P. Ryan, Costel C. Darie, and Alisa G. Woods
    Biomarkers in major depressive disorder: the role of mass spectrometry / Alisa G. Woods, Dan V. Iosifescu, and Costel C. Darie
    Application of mass spectrometry to characterize localization and efficacy of nanoceria in vivo / Karin L. Heckman, Joseph Erlichman, Ken Reed, and Matthew Skeels
    Bottlenecks in proteomics / Armand G. Ngounou Wetie, Devon A. Shipp, and Costel C. Darie.
    Digital Access Springer 2014
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