Bookedited by Noel R. Rose, Ian R. Mackay.
Contents:
Autoimmune disease: reflections and projections
Autoimmunity: a history of the early struggle for recognition
General features of autoimmune disease
Innate and adaptive systems of immunity
Immunological tolerance: T cells
T cells and their subsets in autoimmunity
The role of invariant natural killer T cells in autoimmune diseases
B-cell development: how to become one of the chosen ones
B cell activation and b cell tolerance
Macrophages and autoimmunity
Dendritic cells in autoimmune disease
Natural killer cells
Granulocytes: neutrophils, basophils, eosinophils
The roles and contributions of the complement system in the pathophysiology of autoimmune diseases
Cytokines, their receptors and signals
Cell death and autoimmune disease
Autophagy in autoimmunity
Effector mechanisms in autoimmunity
Diet, the gut microbiome, and autoimmune diseases
Noninfectious environmental agents and autoimmunity
Microbial infection as a trigger of T-cell autoimmunity
Autoimmune diseases: the role for vaccines
Genetic predisposition, humans
Sexual dimorphism in the immune system
Epigenetics of autoimmune diseases
Genetic predisposition to autoimmune diseases conferred by the major histocompatibility complex: utility of animal models
Animal models of organ-specific autoimmune disease
Autoimmunity in primary immunodeficiency disorders
Animal models: systemic autoimmune diseases
Systemic lupus erythematosus
Systemic sclerosis (scleroderma)
Antiphospholipid syndrome
Sjogren’s syndrome
Rheumatoid arthritis
Juvenile idiopathic arthritis
Spondyloarthritides
The autoimmune myopathies
Immunoglobulin g4-related disease
Polyendocrine syndromes
Thyroid disease
Autoimmune (type 1) diabetes
Adrenalitis
Autoimmune hypophysitis
Autoimmune gastritis and pernicious anemia
Celiac disease
Inflammatory bowel disease
Autoimmune hemolytic anemia
Immune thrombocytopenia: a complex autoimmune disease
Acquired aplastic anemia
Autoimmune clotting dysfunction
Multiple sclerosis
Peripheral neuropathies
Myasthenia gravis and related disorders
Ocular disease
Immune-mediated inner ear disease
Autoimmune and autoantibody-associated encephalomyelopathies
Hepatitis
Primary biliary cholangitis
Autoimmune pancreatitis and immunoglobulin g4–related disease
Autoimmune bullous skin diseases: pemphigus and pemphigoid
Nonbullous skin diseases: alopecia areata, vitiligo, psoriasis, and urticaria
Autoimmune orchitis and autoimmune oophoritis
Rheumatic fever and rheumatic heart disease
Myocarditis and dilated cardiomyopathy
Necrotizing arteritis and small-vessel vasculitis
Large and medium-vessel vasculitides
Idiopathic and autoimmune interstitial lung disease
Autoimmune diseases in the kidney
Autoantibody assays: performance, interpretation, and standardization
Prevention of autoimmune disease: the type diabetes paradigm
Treatment of autoimmune disease: established therapies
Emerging biological and molecular therapies in autoimmune disease
Cameos: candidates and curiosities.