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  • Book
    [edited by] John E. Niederhuber, James O. Armitage, James H. Doroshow, Michael B. Kastan, Joel E. Tepper.
    Summary: "Easily accessible and clinically focused, Abeloff's Clinical Oncology, 6th Edition, covers recent advances in our understanding of the pathophysiology of cancer, cellular and molecular causes of cancer initiation and progression, new and emerging therapies, current trials, and much more. Masterfully authored by an international team of leading cancer experts, it offers clear, practical coverage of everything from basic science to multidisciplinary collaboration on diagnosis, staging, treatment and follow up"--Publisher's description.

    Contents:
    Part I: Science and clincial oncology. Section A: Biology and cancer. Molecular tools in cancer research
    Intracellular signaling
    The cellular microenvironment and metastases
    Control of the cell cycle
    The pathophysiology of cancer cell death
    Cancer immunology
    Stem cells, cell differentiation, and cancer
    Vascular and interstitial biology of tumors
    Cancer metabolism
    Section B: Genesis of cancer. Environmental factors
    DNA damage response pathways and cancer
    Viruses and human cancer
    Genetic factors: hereditary cancer predisposition syndromes
    Genetic and epigenetic changes in cancer
    Section C: Diagnosis of cancer. Pathology, biomarkers, and molecular diagnostics
    Imaging
    Section D: Clinical trials. Biostatistics and bioinformatics in clinical trials
    Trial design
    Structures supporting cancer clinical trials
    Oncology and health care policy
    Section E: Prevention and early detection. Discovery and characterization of cancer genetic susceptibility alleles
    Lifestyle and cancer prevention
    Cancer screening and early detection
    Nicotine dependence: current treatments and future directions
    Section F: Treatment. Cancer pharmacology
    Therapeutic targeting of cancer cells: era of molecularly targeted agents
    Basics of radiation therapy
    Hematopoietic stem cell transplantation
    Gene therapy in oncology
    Therapeutic antibodies and immunologic conjugates
    Complementary and alternative medicine
    Part II: Problems common to cancer and therapy
    Section A: Hematologic problems and infections. Disorders of blood cell production in clinical oncology
    Diagnosis, treatment, and prevention of cancer-related venous thrombosis
    Infection in the patient with cancer
    Section B: Symptom management. Hypercalcemia
    Tumor lysis syndrome
    Cancer-related pain
    Cancer cachexia
    Nausea and vomiting
    Section C: Treatment complications. Oral complications
    Dermatologic toxicities of anticancer therapy
    Cardiovascular effects of cancer therapy
    Reproductive complications
    Paraneoplastic neurologic syndromes
    Neurologic complications
    Endocrine complications
    Pulmonary complications of anticancer treatment
    Section D: post treatment considerations. Rehabilitation of individuals with cancer
    Survivorship
    Second malignant neoplasms
    Caring for patients at the end of life
    Section E: Local effects of cancer and its metastasis. Acute abdomen, bowel obstruction, and fistula
    Superior vena cava syndrome
    Spinal cord compression
    Brain metastases and neoplastic meningitis
    Bone metastases
    Lung metastases
    Liver metastases
    Malignancy-related effusions
    Section F: Special populations. Cancer in the elderly: biology, prevention, and treatment
    Special issues in pregnancy
    Human immunodeficiency virus (HIV) infection and cancer
    Part III: Specific malignancies. Section A: Central nervous system. Cancer of the central nervous system
    Section B: Head, neck, and eye. Ocular tumors
    Cancer of the head and neck
    Section C: Skin. Melanoma
    Nonmelanoma skin cancers: basal cell and squamous cell carcinomas
    Section D: Endocrine. Cancer of the endocrine system
    Section E: Thoracic. Cancer of the lung: non-small cell lung cancer and small cell lung cancer
    Diseases of the pleura and mediastinum
    Cancer of the esophagus and gastroesophageal junction
    Section F: Gastrointestinal. Cancer of the stomach and gastroesophageal junction
    Cancer of the small bowel
    Colon cancer
    Cancer of the rectum
    Cancer of the anal canal
    Liver and bile duct cancer
    Carcinoma of the pancreas
    Section G: Genitourinary. Cancer of the kidney
    Carcinoma of the bladder
    Prostate cancer
    Cancer of the penis
    Testicular cancer
    Section H: Gynecological. Cancers of the cervix, vulva, and vagina
    Cancer of the endometrium
    Ovaries and fallopian tubes
    Gestational trophoblastic disease
    Cancer of the breast
    Section I: Sarcomas. Sarcomas of bone
    Sarcomas of soft tissue
    Section J: Cancer of undefined site of origin. Carcinoma of Unknown Primary
    Section K: Pediatrics. Pediatric solid tumors
    Childhood leukemia
    Childhood lymphoma
    Section L: Hematological. Acute leukemias in adults
    Myelodysplastic syndromes
    Myeloproliferative disorders
    Chronic myeloid leukemia
    Chronic lymphoid leukemias
    Hairy cell leukemia
    Multiple myeloma and related disorders
    Hodgkin's Lymphoma
    Non-Hodgkin lymphoma
    Cutaneous T-cell lymphoma and cutaneous B-cell lymphoma
    Adult T-cell leukemia-lymphoma.
    Digital Access ClinicalKey 2020