BookGyan Prakash and Takeshi Iwata, editors.
Summary: This third volume, with three supporting editors, broadens its focus on genetic eye research from the Asian to the global scale. New efforts and a new awareness have sparked important discussions on genetic eye research, and new plans are being implemented to identify the genes responsible for numerous eye diseases. The book introduces the latest findings on genetics in eye diseases, gene therapy, and genome-wide association analysis, and the efforts of the Global Eye Genetic Consortium (GEGC). The books editors have been instrumental in developing strategies for discovering the new genes involved in many eye diseases. All chapters were written by leading researchers working on eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume III is a major resource for all researchers, clinicians, clinical researchers, and allied eye health professionals with an interest in eye diseases around the globe.
Contents:
1. Expansion of Asian Eye Genetics Consortium (AEGC) to Global Eye Genetics Consortium (GEGC), Introduction of a global Phenotype-Genotype Database "GenEye" and Launch of New Training Programs at National Eye Institute (NEI)
2. Global Womens Eye Health: a Genetic Epidemiologic perspective
3. Establishing the Chinese Arm of GEGC
4. Human material for research: Eye banking, biobanking and ethical access
5. Current Understanding of Polypoidal Choroidal Vasculopathy
6. Genetics of Age-related macular degeneration (AMD) in Asia
7. The contribution of rare allele and Junk Genome in AMD pathogenesis
8. Differential genotypes in age-related macular degeneration and polypoidal choroidal vasculopathy: a updated meta-analysis
9. Genetic Epidemiology of Quantitative Traits of Primary Open Angle Glaucoma
10. Association studies on retina diseases in Chinese population
11. Congenital stationary night blindness (CSNB) an inherited retinal disorder where clear correlations can be made
12. Genome analysis for inherited retinal disease: the state of the art
13. Generation and analysis of induced photoreceptor-like cells from fibroblasts of patients with retinitis pigmentosa
14. Genotype-phenotype of RPE65 mutations: A reference guide for gene testing and its clinical application
15. Genetic variants and impact in PDE6B rod-cone dystrophy
16. The retinitis pigmentosa genes
17. Primary Congenital Glaucoma Genetics The Experience in Brazil
18. Glaucoma genetics in Pakistan
19. Contributions of Promoter Variants to Complex Eye Diseases
20. Vascular Basement Membrane Thickening Basis of disease pathology in diabetic retinopathy
21. Molecular Genetics and Clinical aspects of Macular Corneal Dystrophy
22. Congenital and Inherited Cataracts
23. Higher order aberrations: differences among populations from various demographics
24. Genetics Of Microphthalmia: Global And Indian Perspectives
25. Regional Differences in Prevalence of Myopia: Genetic or Environmental Effects?
26. Consortium for Refractive Error and Myopia (CREAM): Vision, Mission and Accomplishments
27. Oncologic properties of retinoblastoma genes
28. Oncologic implications of genetic and epigenetic basis of pterygium
29. The need for alternative therapies in eye disorders
30. Gene Therapy and Retinal Disease
31. The use of human pluripotent stem cells (hPSCs) and CRISPR-mediated gene editing in retinal diseases.