Books

"Textbook in pediatric pharmacology and provides evidence-based guidelines for safe, effective, and rational drug therapy in newborns, children, and adolescents"-- Provided by publisher.

"The Yale Swallow Protocol is an evidence-based protocol that is the only screening instrument that both identifies aspiration risk and, when passed, is able to recommend specific oral diets without the need for further instrumental dysphagia testing. Based upon research by Drs. Steven B. Leder and Debra M. Suiter, an easily administered, reliable, and validated swallow screening protocol was developed and can be used by speech-language pathologists, nurses, otolaryngologists, oncologists, neurologists, intensivists, and physicians assistants. In addition, the protocol can be used in a variety of environments, including acute care, rehabilitation, and nursing homes. The Yale Swallow Protocol meets all of the criteria necessary for a successful screening test, including being simple to administer, cross-disciplinary, cost effective, acceptable to patients, and able to identify the target attribute by giving a positive finding when aspiration risk is present and a negative finding when aspiration risk is absent. Additionally, early and accurate identification of aspiration risk can significantly reduce health-care costs associated with recognized prandial aspiration."--Publisher's website.

This is a comprehensive resource on treatment, rehabilitation, recovery, and public health of persons cared for in organized, publically funded systems of care.

Portable, practical, and entirely clinical, this affordable guide to assessment and management of the entire range of gastroenterological complaints and conditions is ideally suited for use by GI fellows and specialists. The book is divided into two parts: symptom-focused and disease-focused. Features include key practice points, essentials of diagnosis, potential pitfalls, key web links, society guideline comparisons, case studies, and multiple choice questions. When you need answers in a hurry, turn to the most trusted name in gastroenterology: Yamada.

Yamada's Textbook of Gastroenterology. Front Matter -- Development and differentiation of the gastrointestinal system / Jianwen Que, Daniel K Podolsky -- Gut stem cells and tissue renewal / Johan H Es, Sina Bartfeld, Hans Clevers -- Esophagus: anatomy and structural anomalies / Ikuo Hirano -- Stomach and duodenum: anatomy and structural anomalies / Erik C Rosenvinge, Jean-Pierre Raufman -- Small intestine: anatomy and structural anomalies / Anisa Shaker, Deborah C Rubin -- Colon: anatomy and structural anomalies / Bo Shen -- Pancreas: anatomy and structural anomalies / Kazuki N Sugahara, John A Chabot -- Abdominal cavity: anatomy, structural anomalies, and hernias / Stella Joyce, Kevin P Murphy, Michael M Maher, Owen J O'Connor -- Gallbladder and biliary tract: anatomy and structural anomalies / Theodore H Welling -- Liver: anatomy, microscopic structure, and cell types / Maria Westerhoff, Laura Lamps -- Gastrointestinal blood flow / Brian D Hosfield, Troy A Markel -- The innervation of the gastrointestinal tract / John B Furness, Ruslan V Pustovit, Linda J Fothergill, Rachel M McQuade, Martin J Stebbing -- Smooth muscle and pacemakers of the gut / Kenton M Sanders, Brian A Perrino -- Mucosal immune system / Lars Eckmann, Giorgos Bamias -- Epithelia and gastrointestinal function / Sandra D Chanez-Paredes, Jerrold R Turner -- Electrolyte secretion and absorption in the small intestine and colon / Kim E Barrett, Stephen J Keely -- Gastric secretions / John Geibel -- Pancreatic secretion / Kristyn Gumpper, Luis F Lara, Zobeida Cruz-Monserrate, Darwin L Conwell -- Bile secretion and cholestasis / James E Squires, Andrew P Feranchak -- General nutritional principles / Xiaowen Fan, Rebecca Rudel, Matthew Berger, Melissa Hershman, David S Seres -- Nutrient digestion, absorption, and sensing / Shrinivas Bishu, Eamonn M M Quigley -- Vitamins and minerals / Berkeley N Limketkai, Laura E Matarese, Gerard E Mullin -- Nutrition Support / Dong Wook Kim, David S Seres -- Control of food intake / Andres Acosta -- Eating disorders / Leslie Sim, Jocelyn Lebow, Janna R Gewirtz O'Brien -- The aging gastrointestinal tract: digestive and motility problems / Michael Camilleri -- Neoplasia of the gastrointestinal tract / E Ramsay Camp, Denise I Garcia, Raymond N DuBois -- Drug metabolism, transport, and pharmacogenomics / Ann M Moyer, Joel M Reid -- Medical decision making / John M Inadomi -- Approach to the patient

Section 1: The respiratory system. Asthma and chronic obstructive pulmonary disease -- Bronchoscopy, mediastinoscopy, and thoracoscopy -- Aspiration and postoperative respiratory failure -- Lung transplantation -- Section 2: The cardiovascular system. Ischemic heart disease and coronary artery bypass grafting -- Mechanical circulatory support -- Valvular heart disease -- Pacemakers, implantable cardioverter-defibrillators, and cardiac resynchronization therapy devices -- Thoracoabdominal aortic aneurysms -- Abdominal aortic aneurysm repair -- Hypertension -- Cardiac tamponade -- Heart transplantation and subsequent noncardiac surgery -- Ischemic heart disease and noncardiac surgery -- Section 3: The gastrointestinal system. Intestinal obstruction -- Liver transplantation -- Section 4: The nervous system. Brain tumor and craniotomy -- Carotid endarterectomy -- Awake craniotomy for mapping and surgery in the eloquent cortex -- Head injury -- Cerebral aneurysm -- Section 5: The endocrine system. Pheochromocytoma -- Diabetes mellitus -- Section 6: the genitourinary system. Transurethral resection of the prostate -- Kidney transplant -- Robotic-assisted laparoscopic surgery -- Section 7: The reproductive system. Placenta previa/placenta accreta -- Hypertensive disorders of pregnancy -- Breech presentation, fetal distress, and mitral stenosis -- Appendectomy for a pregnant patient -- Section 8: The hematologic system. Hemophilia and coagulation disorders -- Sickle cell disease -- Section 9: Eye, ear, nose, and throat. Airway trauma -- Open-eye injury -- Laser treatment for laryngeal lesions -- Section 10: Pediatrics. Tracheoesophageal fistula -- Congenital diaphragmatic hernia -- Tetralogy of Fallot -- Transposition of the great arteries -- Pyloric stenosis -- Inflammatory airway disease in childhood: laryngotracheobronchitis -- Cleft palate -- Congenital heart disease with a cervical mass in infancy -- Patent ductus arteriosus and prematurity -- Bleeding tonsils -- Section 11: Pain management and neuraxial blocks. Brachial plexus block -- Nerve blocks of the lower extremity -- Complex regional pain syndromes -- Cancer pain -- Low back pain and sciatica -- Perioperative pain management -- Acupuncture -- Section 12: Miscellaneous. Myasthenia gravis -- Malignant hyperthermia -- Postoperative residual neuromuscular weakness and prolonged apnea -- Burns -- Trauma -- Scoliosis -- Hypoxia and equipment failure -- Electroconvulsive therapy -- Ambulatory surgery -- Magnetic resonance imaging -- Morbid obesity, obstructive sleep apnea, and bariatric anesthesia.

"A core text for anesthesia residents, Yao & Artusio's Anesthesiology is case-based and often used in preparation for oral boards. Sections are organized by system and all chapters follow the same format. After a brief presentation of a case, questions are posed regarding; medical disease and differential diagnosis, preoperative planning and preparation, intraoperative management, and postoperative management. Each question is then fully answered and discussed. The four classes of questions conform to the four areas of questioning at the oral boards so working through these considerations repetitively reinforces logical, critical thinking about patient management"-- Provided by publisher.

This book provides a detailed and up-to-date overview of all aspects of yeast cell surface engineering, including fundamental principles, practical strategies for the construction of engineered yeasts, as well as medical and industrial applications. The technique makes it possible to add eukaryotic modifications to the surface-displayed proteins/peptides, which is of significant value in basic and applied research. Generally referred to as an arming (molecular display) technology, it allows yeast to be used as a whole-cell biocatalyst for a range of purposes, including bio-energy production, pollutant removal, recovery of rare metal ions, and preparation of functional cells, all of which are comprehensively covered in the book. Among the medical applications discussed are in vitro antibody preparation and the production of oral vaccines. In addition, it presents the latest advances in protein engineering and high-throughput screening for directed evolution of enzymes. The book enables graduate students and researchers to gain a deeper, comprehensive understanding of the technology, and offers further inspiration for researchers and industrial experts in this rapidly evolving field.

Time-lapse fluorescence microscopy of budding yeast cells / Arun Kumar and Manuel Mendoza -- Real-time visualization and quantification of contractile ring proteins in single living cells / Reshma Davidson ... [et al.] -- Fluorescence recovery after photo-bleaching (FRAP) and fluorescence loss in photo-bleaching (FLIP) experiments to study protein dynamics during budding yeast cell division / Alessio Bolognesi ... [et al.] -- High-speed super-resolution imaging of live fission yeast cells / Caroline Laplante ... [et al.] -- Monitoring chitin deposition during septum assembly in budding yeast / Irene Arcones and Cesar Roncero -- Imaging septum formation by fluorescence microscopy / Juan Carlos Ribas and Juan Carlos G. Cortés -- Visualization of cytokinesis events in budding yeast by transmission electron microscopy / Franz Meitinger and Gislene Pereira -- Visualization of fission yeast cells by transmission electron microscopy / Matthias Sipiczki -- Characterization of septin ultrastructure in budding yeast using electron tomography / Aurélie Bertin and Eva Nogales -- Isolation of cytokinetic actomyosin rings from Saccharomyces cerevisiae and Schizosaccharomyces pombe / Junqi Huang ... [et al.] -- Measurements of myosin-II motor activity during cytokinesis in fission yeast / Qing Tang, Luther W. Pollard, and Matthew Lord -- In vitro biochemical characterization of cytokinesis actin-binding proteins / Dennis Zimmermann ... [et al.] -- Characterization of cytokinetic F-BARs and other membrane-binding proteins / Nathan A. McDonald and Kathleen L. Gould -- Analysis of three-dimensional structures of exocyst components / Johannes Lesigang and Gang Dong -- Analysis of Rho-GTPase activity during budding yeast cytokinesis / Masayuki Onishi and John R. Pringle -- Detection of phosphorylation status of cytokinetic components / Franz Meitinger, Saravanan Palani, and Gislene Pereira -- Studying protein-protein interactions in budding yeast using co-immunoprecipitation / Magdalena Foltman and Alberto Sanchez-Diaz -- Conditional budding yeast mutants with temperature-sensitive and auxin-inducible degrons for screening of suppressor genes / Asli Devrekanli and Masato T. Kanemaki -- Synchronization of the budding yeast Saccharomyces cerevisiae / Magdalena Foltman, Iago Molist, and Alberto Sanchez-Diaz -- Fission yeast cell cycle synchronization methods / Marta Tormos-Pérez, Livia Pérez-Hidalgo, and Sergio Moreno -- Review of fluorescent proteins for use in yeast / Maja Bialecka-Fornal, Tatyana Makushok, and Susanne M. Rafelski -- Visualization and image analysis of yeast cells / Steve Bagley -- Toolbox for protein structure prediction / Daniel Barry Roche and Liam James McGuffin -- From structure to function : a comprehensive compendium of tools to unveil protein domains and understand their role in cytokinesis / Sergio A. Rincon and Anne Paoletti.

Using RNA-seq for analysis of differential gene expression in fungal species / Can Wang ... [et al.] -- Enhancing structural annotation of yeast genomes with RNA-Seq data / Hugo Devillers, Nicolas Morin, and Cécile Neuvéglise -- Pathogen gene expression profiling during infection using a nanostring nCounter platform / Wenjie Xu ... [et al.] -- Comparative transcriptomics in yeasts / Dawn A. Thompson -- Mapping the transcriptome-wide landscape of RBP binding sites using gPAR-CLIP-seq : experimental procedures / Ting Han and John K. Kim -- Mapping the transcriptome-wide landscape of RBP binding sites using gPAR-CLIP-seq : bioinformatic analysis / Mallory A. Freeberg and John K. Kim -- Translation analysis at the genome scale by ribosome profiling / Agnès Baudin-Baillieu ... [et al. ] -- Biotin-genomic run-on (Bio-GRO) : a high-resolution method for the analysis of nascent transcription in yeast / Antonio Jordán-Pla ... [et al.] -- Genome-wide probing of RNA structures in vitro using nucleases and deep sequencing / Yue Wan ... [et al.] -- Genome-wide chromatin immunoprecipitation in Candida albicans and other yeasts / Matthew B. Lohse [et al.] -- ChIPseq in yeast species : from chromatin immunoprecipitation to high-throughput sequencing and bioinformatics data analyses / Gaëlle Lelandais, Corinne Blugeon, and Jawad Merhej -- Systematic determination of transcription factor DNA- binding specificities in yeast / Lourdes Peña-Castillo and Gwenael Badis -- Generation and analysis of chromosomal contact maps of yeast species / Axel Cournac ... [et al.] -- Versatile procedure to generate genome-wide spatiotemporal program of replication in yeast species / Nicolas Agier and Gilles Fischer -- Single-step affinity purification (ssAP) and mass spectrometry of macromolecular complexes in the yeast S. cerevisiae / Christian Trahan, Lisbeth-Carolina Aguilar, and Marlene Oeffinger -- Label-free quantitative proteomics in yeast / Thibaut Léger ... [et al.] -- Profiling of yeast lipids by shotgun lipidomics / Christian Klose and Kirill Tarasov -- Identification of links between cellular pathways by genetic interaction mapping (GIM) / Christophe Malabat and Cosmin Saveanu -- On the mapping of epistatic genetic interactions in natural isolates : combining classical genetics and genomics / Jing Hou and Joseph Schacherer -- Experimental evolution and resequencing analysis of yeast / Celia Payen and Maitreya J. Dunham -- Reconstruction and analysis of the evolution of modular transcriptional regulatory programs using arboretum / Sara A. Knaack, Dawn A. Thompson, and Sushmita Roy -- Predicting gene and genomic regulation in Saccharomyces cerevisiae, using the YEASTRACT database : a step-by-step guided analysis / Miguel C. Teixeira, Pedro T. Monteiro, and Isabel Sá-Correia.

Yeast transformation by the LiAc/SS carrier DNA/PEG method / R. Daniel Gietz -- Tetrad, random spore, and molecular analysis of meiotic segregation and recombination / Michael Lichten -- PCR mutagenesis and gap repair in yeast / Mark Weir and Jill B. Keeney -- PCR-mediated epitope tagging of genes in yeast / Radhika Mathur and Peter Kaiser -- Manipulating the yeast genome : deletion, mutation, and tagging by PCR / Jennifer M. Gardner and Sue L. Jaspersen -- Preparation of yeast cells for live-cell imaging and indirect immunofluorescence / Lucy F. Pemberton -- Single yeast cell imaging / Heimo Wolinski and Sepp D. Kohlwein -- Microfluidic platforms for generating dynamic environmental perturbations to study the responses of single yeast cells / Anjali Bisaria, Pascal Hersen, and Megan N. McClean -- Using two-hybrid interactions to identify separation-of- function mutations / Brian Haarer and David C. Amberg -- Synthetic genetic array analysis for global mapping of genetic networks in yeast / Elena Kuzmin [and six others] -- Chemical genetic and chemogenomic analysis in yeast / Namal V. C. Coorey [and three others] -- Phenomic assessment of genetic buffering by kinetic analysis of cell arrays / John Rodgers, Jingyu Guo, and John L. Hartman IV -- Detection of short-range chromatin interactions by chromosome conformation capture (3C) in yeast / Badri Nath Singh and Michael Hampsey -- Chromosome conformation capture (3C) of tandem arrays in yeast / Maria D. Mayán and Luis Aragón -- Global analysis of transcription factor-binding sites in yeast using ChIP-Seq / Philippe Lefrançois, Jennifer E. G. Gallagher, and Michael Snyder -- High-density tiling microarray analysis of the full transcriptional activity of yeast / Lior David, Sandra Clauder-Münster, and Lars M. Steinmetz -- Analysis of silencing in Saccharomyces cerevisiae / Andrew Miller and Ann L. Kirchmaier -- A user's guide to the ribosomal DNA in Saccharomyces cerevisiae / Joseph M. Johnson, Jeffrey S. Smith, and David A. Schneider -- Two-dimensional agarose gel electrophoresis for analysis of DNA replication / Sandra K. Villwock and Oscar M. Aparicio -- Replicative life span analysis in budding yeast / George L. Sutphin, Joe R. Delaney, and Matt Kaeberlein -- Metabolomic and lipidomic analyses of chronologically aging yeast / Vincent R. Richard, Simon D. Bourque, and Vladimir I. Titorenko.

Membrane transport in yeast: an introduction -- Cell surface interference with plasma membrane and transport processes in yeasts -- 3. Proton transport and pH control in fungi -- 4. Function and regulation of fungal amino acid transporters: insights from predicted structure -- 5. Water transport in yeasts -- 6. Sugar and glycerol transport in Saccharomyces cerevisiae -- 7. The CRaZy calcium cycle -- 8. Potassium and sodium transport in yeast -- 9. Carboxylic acids plasma membrane transporters in Saccharomyces cerevisiae -- 10. Inorganic phosphate and sulfate transport in S. cerevisiae -- 11. Interactions between monovalent cations and nutrient homeostasis -- 12. Mathematical modelling of cation transport and regulation in yeast -- 13. Transport systems in halophilic fungi -- 14. Antifungals: mechanism of action and drug resistance -- 15. Candida efflux ATPases and antiporters in clinical drug resistance-- Index.

An overview on selection marker genes for transformation of Saccharomyces cerevisiae -- Natural and modified promoters for tailored metabolic engineering of the yeast Saccharomyces cerevisiae -- Tools for genetic engineering of the yeast Hansenula polymorpha -- Molecular tools and protocols for engineering the acid-tolerant yeast Zygosaccharomyces bailii as a potential cell factory -- Strains and molecular tools for recombinant protein production in Pichia pastoris -- Methods for efficient high-throughput screening of protein expression in recombinant pichia pastoris strains -- Synthetic RNA switches for yeast metabolic engineering: Screening recombinant enzyme libraries -- Generation of arming yeasts with active proteins and peptides via cell surface display system: Cell surface engineering, bio-arming technology -- Genetic engineering of industrial Saccharomyces cerevisiae strains using a selection/counter-selection approach -- Evolutionary engineering of yeast -- Determination of a dynamic feeding strategy for recombinant pichia pastoris strains -- Yeast metabolomics: Sample preparation for a GC/MS based analysis -- 13CC-based metabolic flux analysis in yeast: The Pichia pastoris case -- Pathway activity profiling (PAPi): A tool for metabolic pathway analysis -- QTL mapping by pooled-segregant whole-genome sequencing in yeast -- Genome-scale metabolic models of yeast, methods for their reconstruction, and other applications -- Model-guided identification of gene deletion targets for metabolic engineering in Saccharomyces cerevisiae -- Patents: A tool to bring innovation from the lab bench to the marketplace.

Basic investigations in Saccharomyces cerevisiae / Brendan P.G. Curran and Virginia Bugeja -- Isolation of yeast nucleic acids / Michael Biss, Michelle D. Hanna, and Wei Xiao -- Quantification of GFP signals by fluorescent microscopy and flow cytometry / Ting Wei and Heping Dai -- Yeast transformation by the LiAc/SS carrier DNA/PEG method / R. Daniel Gietz -- Targeted gene deletion in Saccharomyces cerevisiae and Schizosaccharomyces pombe 45 / Johannes H. Hegemann ... [et al.] -- See & catch method for studying protein complexes in yeast cells : a technique unifying fluorescence microscopy and mass spectrometry / Changhui Deng and Andrew N. Krutchinsky -- Yeast two-hybrid liquid screening / Elisa Donnard ... [et al.] -- Targeted mutagenesis of a specific gene in yeast / Likui Zhang, Alina Radziwon, and Linda J. Reha-Krantz -- Fluorescence staining of mitochondria for morphology analysis in Saccharomyces cerevisiae / Kai Stefan Dimmer -- Assays for autophagy I : the Cvt pathway and nonselective autophagy / Wei-Pang Huang, Takahiro Shintani, and Zhiping Xie -- Assays for autophagy II : mitochondrial autophagy / Tomotake Kanki and Koji Okamoto -- Biochemically characterizing the subcellular localization of peroxisomal proteins by fractionation, protease protection, and carbonate extraction / Danielle Hagstrom and Changle Ma -- Yeast survival and growth assays / Xin Xu, Amanda D. Lambrecht, and Wei Xiao -- Spontaneous mutagenesis assay / Susan Blackwell, Michelle D. Hanna, and Wei Xiao -- Mutational specificity analysis : assay for mutations in the yeast SUP4-o gene / Bernard A. Kunz -- piggyBac transposon-based insertional mutagenesis for the fission yeast Schizosaccharomyces pombe / Jun Li and Li-Lin Du -- Replicative and chronological life-span assays / Spike D.L. Postnikoff and Troy A.A. Harkness -- Detection of protein arginine methylation in Saccharomyces cerevisiae / Christopher A. Jackson and Michael C. Yu -- Detection of protein posttranslational modifications from whole-cell extracts in Saccharomyces cerevisiae / Lindsay G. Ball and Wei Xiao -- Ligand engineering using yeast surface display / Benjamin J. Hackel -- Screening combinatorial libraries of cyclic peptides using the yeast two-hybrid assay / Kris Barreto and C. Ronald Geyer.

Protein engineering and selection using yeast surface display / Alessandro Angelini [and eight others] -- Isolation and validation of Anti-B7-H4 scFvs from an ovarian cancer scFv yeast-display library / Denarda Dangaj and Nathalie Scholler -- Combining phage and yeast cell surface antibody display to identify novel cell type-selective internalizing human monoclonal antibodies / Scott Bidlingmaier, Yang Su, and Bin Liu -- Yeast display-based antibody affinity maturation using detergent-solubilized cell lysates / Benjamin J. Tillotson, Jason M. Lajoie, and Eric V. Shusta -- Yeast endoplasmic reticulum sequestration screening for the engineering of proteases from libraries expressed in yeast / Li Yi [and five others]] -- T cell receptor engineering and analysis using the yeast display platform / Sheena N. Smith, Daniel T. Harris, and David M. Kranz -- Epitope-specific binder design by yeast surface display / Jasdeep K. Mann and Sheldon Park -- Applications of yeast surface display for protein engineering / Gerald M. Cherf and Jennifer R. Cochran -- Identification of novel protein-ligand interactions by exon microarray analysis of yeast surface displayed cDNA library selection outputs / Scott Bidlingmaier and Bin Liu -- Identification of posttranslational modification-dependent protein interactions using yeast surface displayed human proteome libraries / Scott Bidlingmaier and Bin Liu -- Utilizing yeast surface human proteome display libraries to identify small molecule-protein interactions / Scott Bidlingmaier and Bin Liu -- Enzyme evolution by yeast cell surface engineering / Natsuko Miura, Kouichi Kuroda, and Mitsuyoshi Ueda -- Electrochemical glucose biosensor based on glucose oxidase displayed on yeast surface / Hongwei Wang [and three others] -- Coupling binding to catalysis : using yeast cell surface display to select enzymatic activities / Keya Zhang [and three others] -- The use of yeast surface display in biofuel cells / Alon Szczupak and Lital Alfonta.

This book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research. The use of yeasts as experimental eukaryotic models increasingly gained prominence when several Nobel Prizes in Physiology/Medicine and Chemistry were awarded for innovative research, using yeast strains to elucidate molecular mechanisms in a wide range of human physiological processes and diseases, such as autophagy, cell cycle regulation and telomerase activity. This book offers useful insights for scientists in yeast research, clinical scientists working with yeast infectious models and for industrial researchers using applied microbiology.

It is well established that certain strains of yeasts are suitable for transforming grape sugars into alcohol, while other yeast strains are not suitable for grape fermentations. Recent progress has clearly demonstrated that the sensory profile of a wine is characteristic of each vine cultivated, and the quality and technological characteristics of the final product varies considerably due to the strains which have performed and/or dominated the fermentation process. Because of their technological properties, wine yeast strains differ significantly in their fermentation performance and in their contribution to the final bouquet and quality of wine, such as useful enzymatic activities and production of secondary compounds related both to wine organoleptic quality and human health. The wine industry is greatly interested in wine yeast strains with a range of specialized properties, but as the expression of these properties differs with the type and style of wine to be made, the actual trend is in the use of selected strains, which are more appropriate to optimize grape quality. Additionally, wine quality can be influenced by the potential growth and activity of undesirable yeast species, considered spoilage yeasts, which cause sluggish and stuck fermentation and detrimental taste and aroma in the wine.

Part 1. Endocrinology of reproduction. Neuroendocrinology of reproduction -- Gonadotropin hormones and their receptors -- Prolactin in human reproduction -- Steroid hormones and other lipid molecules involved in human reproduction -- Steroid hormone action -- Growth factors and reproduction -- Neuroendocrine control of the menstrual cycle -- The ovarian life cycle -- Structure, function, and evaluation of the female reproductive tract -- The breast -- Endocrinology of human pregnancy and fetal-placental neuorendocrine development -- Hypothalamo-pituitary unit, testis, and male accessory organs -- Immunology and reproduction -- Menopause and aging -- Male reproductive aging -- Part 2. Pathophysiology and therapy: pediatric, adolescent, and adult. Disorders of sex development -- Puberty: gonadarche and adrenarche -- Nutrition and reproduction -- Environmental factors and reproduction -- Physiological and pathophysiological alterations of the neuroendocrine components of the reproductive axis -- Polycystic ovary syndrome and hyperandrogenic states -- Female infertility -- Male infertility -- Endocrine disturbances affecting reproduction -- Endometriosis -- Benign uterine diseases -- Endocrine diseases in pregnancy -- Transgender hormonal treatment -- Hormone-responsive cancers -- Part 3. Reproductive technologies. Medical approaches to ovarian stimulation for infertility -- Assisted reproduction -- Gamete and embryo manipulation -- Fertility preservation -- Laboratory asessment -- Pelvic imaging in reproductive endocrinology -- Contraception.

Plague: a disease which changed the path of human civilization / Barbara Bramanti, Nils Chr. Stenseth, Lars Walløe, Xu Lei -- Discovery of the plague pathogen: lessons learned / Ruifu Yang, Thomas Butler -- Taxonomy of Yersinia pestis / Zhizhen Qi, Yujun Cui, Qingwen Zhang, Ruifu Yang -- Physiology of Yersinia pestis / Robert R. Brubaker -- Ecology of Yersinia pestis and the epidemiology of plague / Vladimir M. Dubyanskiy, Aidyn B. Yeszhanov -- Genome and evolution of Yersinia pestis / Yujun Cui, Yajun Song -- Pathology and pathogenesis of Yersinia pestis / Zongmin Du, Xiaoyi Wang -- Genetic regulation of Yersinia pestis / Yanping Han, Haihong Fang, Lei Liu, Dongsheng Zhou -- Yersinia pestis in the age of big data / Ruifu Yang, Vladimir L. Motin -- Immunology of Yersinia pestis infection / Yujing Bi -- Plague: clinics, diagnosis and treatment / Vladimir V. Nikiforov, He Gao, Lei Zhou, Andrey Anisimov -- Plague vaccines: status and future / Wei Sun -- Bacteriophages of Yersinia pestis / Xiangna Zhao, Mikael Skurnik -- Perspectives on Yersinia pestis: a model for studying zoonotic pathogens / Ruifu Yang, Yujun Cui, Yujing Bi.

This book attempts to bridge the considerable gaps that exist between spiritual philosophies and evidence-based medicine and between the psychotherapeutic models of the East and the West. Based on the insights of both the ancient wisdom and modern medicine, this book presents Yogic science not just as a set of physical exercises or religious rituals but as theories about the mind that have bio-psycho-social implications in relation to health and illness. Drawing on his years of monastic training and his extensive experiential, clinical, and research knowledge on the utility of Yoga meditation in standardized and evidence-based medicine protocols, the author describes symptom-specific clinical applications of Yogic/meditative techniques using standardized protocols for the various psychiatric and psychosomatic conditions. In addition, he explains the value of these techniques in reducing stress and improving quality of life in healthy populations. Dr. Pradhan names the proposed integrative model of psychotherapy Yoga and Mindfulness Based Cognitive Therapy (Y-MBCT). Unlike other models, Y-MBCT uses Yoga in its entirety (all eight limbs, including meditation) rather than piecemeal. The standardized and evidence-based format of Yoga meditation described in this book will help all aspiring Yoga practitioners and will hopefully also provide the impetus for multicenter research studies on the value of this ancient wisdom.

Yogurt composition -- Yogurt consumption -- Weight management and obesity -- Type 2 diabetes -- Hypertension -- Cardiovascular disease -- Metabolic syndrome -- Yogurt and gut health -- Immune responses -- Cancer -- Allergy and atopic diseases -- Bone mineralization and osteoporosis.

This book describes a standardized method for classifying and reporting invasive endometrial malignancies via direct endometrial sampling. Featuring a wealth of color illustrations, it provides specific diagnostic categories and cytomorphologic criteria to promote uniform and reliable diagnoses. It also describes the history of directly sampled endometrial cytology, reviews the sampling techniques and algorithmic approach, discusses specimen adequacy, and outlines challenges for the future. The Yokohama System for Reporting Endometrial Cytology Definitions, Criteria and Explanatory Notes offers a valuable resource for researchers at clinical cytopathological laboratories around the world whose work involves gynecological cytology, oncology, pathology, and cytopathology. It will also appeal to researchers in the fields of cytotechnology, basic science, pathology and related industries, medical residents and clinicians.

This stark, potent collection of essays on Black shame and healing present a space to be vulnerable and affirm the fullness of Black love and Black life. They allow readers to recognize and process the trauma of sexual assault, and white supremacy and sexual assault, in order to work toward healing. Through lived experiences, we can work to dismantle oppressive systems-- of all types-- in this country. -- adapted from jacket and Introduction.

What if learning about changing bodies wasn't secretive or shameful? And what if it could even be inclusive, fun, and, well, kind of adorable? A new kind of puberty guide, You-ology embraces an inclusive approach that normalizes puberty for all kids.

The Deep South has seen a 36 percent increase in AIDS cases while the rest of the nation has seen a 2 percent decline. Many of the underlying reasons for the disease's continued spread in the region--ignorance about HIV, reluctance to get tested, non-adherence to treatment protocols, resistance to behavioral changes--remain unaddressed by policymakers. In this extensively revised second edition, Kathryn Whettan and Brian Wells Pence present a rich discussion of twenty-five ethnographic life stories of people living with HIV in the South. Most importantly, they incorporate research from their recent quantitative study, "Coping with HIV/AIDS in the Southeast" (CHASE), which includes 611 HIV-positive patients from North Carolina, South Carolina, Georgia, Alabama, and Louisiana. This new edition continues to bring the participant's voices to life while highlighting how the CHASE study confirmed many of the themes that originally emerged from the life histories. This is the first cohesive compilation of up-to-date evidence on the unique and difficult aspects of living with HIV in the Deep South.

This text covers the major controversies and "myths" in each of the major anesthesia subspecialties. You're Wrong, I'm Right is designed to be an easy and engaging evidence based read that offers the fast-paced give-and-take of a debate between two experts at the top of their game--capturing their full argument, including expressions of humor and displays of temper. Each point of contention begins with a real case, carefully selected to encapsulate the argument. One author then argues the "pro" side and another the "con." Sometimes a single author may argue both sides. In doing so, the authors highlight the newest evidence and remind us of classic principles that have stood the test of time. At the end of the debate, readers can determine which argument they will use in their clinical practice, and may also consult a final "Consensus” section that identifies the editors' and contributors' "picks" of the one best practice in a range of different situations. --supplied by publisher

AM:STARs: Adolescent Medicine: State of the Art Reviews is the official publication of the AAP Section on Adolescent Health. Published 3 times per year, the journal offers adolescent medicine specialists and other primary care physicians who treat adolescent patients with state of the art information on all matters relating to adolescent health and wellness. In this issue, Young Adult Health, topics include: Approaching young adult health and medicine from a developmental perspective Seizing the opportunity: Improving Young Adult Preve.

This book reviews the anatomy, imaging, and variety of surgical modalities available for the full spectrum of presentations of hip disease. Coverage ranges from problems in childhood and adolescence that limit activity, all the way through to sports-related problems with articular cartilage, the labrum, and impingement.

"Have you ever gotten chills while listening to a particularly gorgeous piece of music? Or felt a sense of calm while gazing at a painting of a serene landscape? We have experiences like those every day, but rarely stop to consider what's happening internally to cause them. In Your Brain on Art, founder of the International Arts + Mind Lab at Johns Hopkins University School of Medicine Susan Magsamen and Google designer Ivy Ross explain how, by understanding how we biologically react to aesthetic experiences, we can not only heal as individuals but thrive as communities. Using the new science of neuroaesthetics, which explores our physiological reactions to art, Magsamen and Ross show us how, for instance, gardening can help a person heal from trauma or listening to a major fifth interval can snap the body out of a fight-or-flight response. Beyond enjoyment and abstraction, art can change the way we operate on a daily, practical level. And, in addition to helping each of us heal from stress, anxiety, burnout, and other malaises of modern life, neuroaesthetics can effect major change in society writ large, whether through public art murals in high-crime areas or music and dance therapy for patients experiencing neurodegenerative disorders"-- Provided by publisher.

The book is a ready reckoner aimed at the student community aspiring to take up a career in bioinformatics. The book firstly provides a perspective on the domain and addresses the challenges faced by community namely the attempts to understand data produced by genome sequencing projects. It then brings to light High Performance Computing (HPC) as it helps in interpreting and analyzing genome sequences. The book also dwells on how interactions in a systems (organism), the components that interact with each other and the outcome of such interactions. It then calls for a consensus on the tools like rapid and inexpensive DNA sequencing technologies, HAPMAP projects, Dollar One Genome (DOG), to enable a reader understand how bioinformatics transits from research, to vocation and avocation. Further it extols the virtues of in silico for bioinformatical predictions as it helps wet-lab biologists reduce time for experiments. Also it describes the intricacies of bioinformatics and its usefulness to wet-based biologists and other cross-disciplinarians. The book lists out 10 reasons for taking up bioinformatics as a career, and includes insights from global experts on the domain. It also makes a case for a mediocre student getting into bioinformatics with discipline, determination, dynamism and diligence. The book further describes BioinformaTICKS a tool for emerging as a winner in bioinformatics.

"Designed as an informational resource for patients, Your Pregnancy and Childbirth: Month to Month, Seventh Edition sets forth current information and clinical opinions on subjects related to women's health and reproduction. Your Pregnancy and Childbirth: Month to Month is a resource for informational purposes. Topics include : getting ready for pregnancy -- choosing who will care for you during pregnancy -- what to expect during each month of pregnancy -- exercise during pregnancy -- work and travel during pregnancy -- pain relief during childbirth -- labor and delivery -- cesarean birth -- postpartum care and taking care of the baby after birth -- birth control after pregnancy"-- Provided by publisher

"This book will help the reader get to know their unconscious mind through a series of exercises. Results will serve all curious readers well, especially psychotherapists, writers, artists, actors and others working in the world of creativity. It is important for all of us to achieve a deeper understanding of who we are, with the satisfaction that commonly comes with that. Readers will be able to set free their hidden selves to direct their lives in new and satisfying directions. Humans have a complex unconscious mind, containing vital information about who we are, who we were and where we are going. Sigmund Freud deserves the most credit for pointing systematically to channels of access. Today's neuroscience has tested these points of access and is suggesting new ones. This book introduces five well-established methods of gaining useful access to our unconscious mind.The authors have taught the theory, science, and practice discussed in this book for over fifteen years at Stanford University to people of all ages, backgrounds, and interests. "--Provided by publisher.

This book collects the essential essays and poems of Audre Lorde for the first time, including the classic 'The Master's Tools Will Never Dismantle the Master's House'. A trailblazer in intersectional feminism, Lorde's luminous writings have inspired a new generation of thinkers and writers charged by the Black Lives Matter movement. Her lyrical and incisive prose takes on sexism, racism, homophobia, and class; reflecting struggle but ultimately offering messages of hope that remain ever-more trenchant today. Also a celebrated poet, Lorde was New York State Poet Laureate until her death; her poetry and prose together produced an aphoristic and incomparably quotable style, as evidenced by the constant presence on many Women's Marches against Trump across the world. This beautiful edition honours the ways in which Lorde's work resonates more than ever thirty years after they were first published.

Front matter -- Developmental pathways to substance use and co-occurring psychiatric disorders in adolescents / Ralph E. Tarter, Ph. D., Michelle S. Horner, D.O -- Relationship between substance use disorders and psychiatric comorbidity -- Implications for integrated health services / Marc Fishman, M.D -- Screening, assessment, and treatment options for youths with a substance use disorder / Yifrah Kaminer, M.D., M.B.A., Ken C. Winters, Ph. D., John Kelly, Ph. D -- Conduct disorder and delinquency and substance use disorders / Oscar G. Bukstein, M.D., M.P.H -- Attention-deficit/hyperactivity disorder and substance use disorders / Timothy E. Wilens, M.D., Courtney A. Zulauf, B.A -- Depressive disorders and substance use disorders / John F. Curry, Ph. D., ABPP, Jacqueline Hersh, Ph. D -- Bipolar disorders and substance use disorders / Anne Duffy, M.D., M. Sc., FRCPC, Maryam Nemati, M.A., CCC -- Anxiety disorders and substance use disorders / Jessica J. Black, Ph. D., Tammy Chung, Ph. D., Duncan B. Clark, M.D., Ph. D -- Posttraumatic stress disorder and substance use disorders / Julian D. Ford, Ph. D., Josephine M. Hawke, Ph. D -- Suicidal and nonsuicidal self-harm behaviors and substance use disorders / Christianne Esposito-Smythers, Ph. D., Alexandra Perloe, M.A., Kyla Machell, M.A., Bethany Rallis, M.A -- Schizophrenia and substance use disorders / Kara Simone Bagot, M.D., Robert Milin, M.D., FRCPC -- Eating disorders and substance use disorders / Jessica H. Baker, Ph. D., Lauren M. Metzger, LCSWA, Cynthia M. Bulik, Ph. D -- Youth gambling problems / Jeffrey L. Derevensky, Ph. D -- Pathological preoccupation with the internet / Yvonne H.C. Yau, M. Sc., Jeffrey L. Derevensky, Ph. D., Marc N. Potenza, M.D., Ph. D.