Books

At the 1900 Paris Exposition, the famed sociologist and civil rights activist W. E. B. Du Bois presented a series of groundbreaking data visualizations advocating for African American progress. These graphs, charts, and maps provided powerful glimpses into the lives of black Americans to convey both a literal and figurative representation of what Du Bois famously referred to as "the color line." From advances in education to the lingering effects of slavery, these infographics - beautiful in design and impactful in content - made visible a wide spectrum of black experience. W. E. B. Du Bois's Data Portraits collets the complete set of infographics for the first time in full color, making their insights and innovations available to a contemporary audience while exploring their context in social and design history. As Du Bois's prophetic work continues to grow in potency and relevance, these images illustrate, in the words of the introduction, how "data might be reimagined as a form of accountability and even protest in the age of Black Lives Matter." -- From back cover.

The second edition of Laboratory Administration for Pathologists covers all aspects of clinical and anatomic pathology laboratory administration. Taking a practical approach, this book provides the core principles and tools of management for the practice of pathology and laboratory medicine. The basics of financial, operations, and quality management are covered and complemented by rarely found discussions of the “soft” sides of management and leadership, such as communication, ethics, and decision making. Personnel sections separately address important issues for the large laboratory as well as independent group practice; another section is aimed at pathologists who are seeking and evaluating a position themselves. Included are summaries and case studies, which carry the text beyond a straightforward reference for practitioners, serving as a self-study curriculum for a laboratory management course. Pathologists will find this text useful either as a quick reference tool or to review management for maintenance of certification. Residents will find this text valuable for board preparation and in rotations related to management training. Includes updated content throughout and a new chapter on patient safety.

This book sheds new light on clinical, biological and therapeutic data on the rare disease Waldenström's Macroglobulinemia (WM) with the participation of widely-recognized experts, involved in this field. It represents the efforts of physicians, scientists and patients, all around the world, to better understand and cure this rare disease. Considerable advances in the diagnosis, treatment indications, response criteria, prognostic factors and treatment options have been made since Dr Jan Waldenström first reported this "new syndrome" 70 years ago. Particularly instrumental in advancing of our understanding of WM have been the eight international workshops devoted to this disease. New, exciting molecular data have recently been reported, allowing us to revisit the oncogenic events leading to WM B-cell proliferation and to use newly available compounds targeting oncogenic pathways.

Head -- Neck -- Shoulder -- Elbow and Forearm -- Wrist and hand -- Chest wall, trunk, abdomen and low back -- Hip and pelvis -- Knee and lower extremity -- Foot and ankle.

FALTs: factors affecting laboratory tests -- Laboratory tests -- Infectious disease assays -- Autoimmune diseases -- Cardiovascular disorders -- Central nervous system disorders -- Digestive diseases -- Endocrine diseases -- Genitourinary system disorders -- Gynecologic and obstetric disorders -- Hematologic disorders -- Hereditary and genetic diseases -- Infectious diseases -- Renal disorders -- Respiratory, metabolic, and acid-base disorders -- Toxicology and therapeutic drug monitoring -- Transfusion medicine -- Appendix: Abbreviations and acronyms.

"Wallach's Interpretation of Diagnostic Tests, 10th Edition serves as a practical guide to the use of laboratory tests which aids physicians in using tests more effectively and efficiently by offering test outcomes, possible meanings, differential diagnosis, and summaries of tests available. The book is organized into 2 sections. The first section is devoted to disease states. Where appropriate, a patient's chief complaint and/or physical findings are initially presented with subsequent discussions focused on discrete disease states as they relate to a patient's chief complaint. The second section is devoted to an alphabetical listing of laboratory tests while stressing the integration of the clinical laboratory in the clinical decision making process. Test sensitivity, specific and possible and negative probabilities are included whenever appropriate. Microbiology tests are listed in a separate chapter"--Provided by publisher.

Examination of the visual sensory system -- Anatomy and physiology of the retina and optic nerve -- Congenital anomalies of the optic disc -- Topical diagnosis of acquired optic nerve disorders -- Papilledema -- Optic neuritis -- Ischemic optic neuropathies -- Compressive and infiltrative optic neuropathies -- Traumatic optic neuropathies -- Toxic and deficiency optic neuropathies -- Hereditary optic neuropathies -- Topical diagnosis of chiasmal and retrochiasmal lesions -- Central disorders of visual function -- Examination of the pupils and accommodation -- Disorders of pupillary function and accommodation -- Examination of ocular motility and alignment -- Supranuclear and internuclear ocular motor disorders -- Nuclear and infranuclear ocular motility disorders -- Disorders of neuromuscular transmission -- Myopathies of neuro-ophthalmologic significance -- Nystagmus and related ocular motility disorders -- Normal and abnormal eyelid function -- Neuro-ophthalmologic manifestations of nonorganic disease.

Offering authoritative, concise coverage of today's neuro-ophthalmology, Walsh & Hoyt's Clinical Neuro-Ophthalmology: The Essentials distills the most vital information from the esteemed three-volume parent text, Walsh & Hoyt's Clinical Neuro-Ophthalmology, into a convenient, single-volume resource. A practical and intuitive organization provides quick access to the essential information you need to effectively evaluate and manage the majority of neuro-ophthalmic conditions. Written by leaders in the field, this must-have fourth edition is a comprehensive, succinct, and clinically relevant reference for your everyday practice.

Anatomy of the lower urinary tract, pelvic floor, and rectum -- Embryology and congenital anomalies of the urinary tract, rectum, and female genital system -- Neurophysiology and pharmacology of the lower urinary tract -- Physiology of the pelvic muscles, vagina, and anorectum -- Pathophysiology of pelvic floor disorders -- Epidemiology and psychosocial impact of female pelvic floor disorders -- Synthetic mesh and biologic grafts: Properties and biomechanics -- Description and classification of lower urinary tract dysfunction and pelvic organ prolapse -- Evaluation of pelvic floor disorders: History, physical examination, and diagnostic testing -- Female sexual function and dysfunction: Assessment and treatment -- Urodynamics: Indications, techniques, interpretation, and clinical utility -- Endoscopic assessment of the lower urinary tract -- Radiologic studies of the lower urinary tract and pelvic floor -- Stress urinary incontinence and pelvic organ prolapse: Nonsurgical management -- Retropubic operations for stress urinary incontinence -- Biologic bladder neck slings for stress urinary incontinence -- Synthetic midurethral slings for stress urinary incontinence -- Urethral injection of bulking agents for intrinsic sphincter deficiency -- Surgical treatment of anterior vaginal wall prolapse -- Surgical treatment of posterior vaginal wall prolapse -- Surgical treatment of vaginal apex prolapse -- Uterine preservation in pelvic organ prolapse surgery -- Obliterative procedures for pelvic organ prolapse -- Avoiding and managing lower urinary tract injuries during pelvic surgery -- Managing mesh complications after surgeries for urinary incontinence and pelvic organ prolapse -- Complications of pelvic reconstructive surgery -- Fecal incontinence -- Constipation -- Rectovaginal fistula and perineal breakdown -- Full-thickness rectal prolapse -- Overactive bladder syndrome, polyuria, and nocturia -- Refractory overactive bladder -- Neurourology and compliance abnormalities -- Voiding dysfunction in women -- Interstitial cystitis/bladder pain syndrome -- Lower urinary tract infection -- Urethral diverticula -- Lower urinary tract fistulas -- Bladder drainage and urinary protective methods -- Urology for the urogynecologist -- Outcomes and quality-of-life measures in pelvic floor research.

For more than twenty-five years, David Nott has taken unpaid leave from his job as a general and vascular surgeon with the NHS to volunteer in some of the world's most dangerous war zones. From Sarajevo under siege in 1993, to clandestine hospitals in rebel-held eastern Aleppo, he has carried out life-saving operations and field surgery in the most challenging conditions, and with none of the resources of a major London teaching hospital. The conflicts he has worked in form a chronology of twenty-first-century combat: Afghanistan, Sierra Leone, Liberia, Darfur, Congo, Iraq, Yemen, Libya, Gaza and Syria. But he has also volunteered in areas blighted by natural disasters, such as the earthquakes in Haiti and Nepal. Driven both by compassion and passion, the desire to help others and the thrill of extreme personal danger, he is now widely acknowledged to be the most experienced trauma surgeon in the world. But as time has gone on, David Nott began to realize that flying into to a catastrophe whether war or natural disaster was not enough. Doctors on the ground needed to learn how to treat the appalling injuries that war inflicts upon its victims. Since 2015, the Foundation he set up with his wife, Elly, has disseminated the knowledge he has gained, training other doctors in the art of saving lives threatened by bombs and bullets. War Doctor is his extraordinary story.

In the relatively few decades since the introduction of HIV into the human population, variants of the virus have diverged to such an extent that, were the discussion about something other than viruses, said variants could easily be classified as different species. This book will consider these evolutionary variations, as well as the different and, at times, opposing theories attempting to explain them. It will compare and contrast the ways in which the immune system and drugs affect the virus's evolution, and the implications of these for vaccine development. The issue will be explored and explained through "ecological genetics," which postulates that all living organisms have, besides rivals, enemies. This is divergent from the more traditional school of "population genetics," which emphasizes that evolution occurs among rival species (or variants thereof) that compete for niches or resources in a fixed, unreactive environment. Both models will be formulated using mathematical models, which will be included in the book. Finally, it will consider the possibilities for designing a vaccine that blocks HIV from escaping the immune system.

Neurology and war : from antiquity to modern times / Paciaroni, M., Arnao, V. -- Neurosurgical work during the Napoleonic wars : George James Guthrie's experience / Roux, F.-E -- Impact of 20th century wars on the development of neurosurgery / Dowdy, J., Pait, T.G. -- Elaboration of the visual pathways from the study of war-related cranial injuries : the period from the Russo-Japanese War to World War I / Lanska, D.J. -- Publications on peripheral nerve injuries during World War I : a dramatic increase in knowledge / Koehler, P.J. -- The influence of the two world wars on the development of rehabilitation for spinal cord injuries in the United States and Great Britain / Lanska, D.J. -- Traumatic brain injury studies in Britain during World War II / Lanska, D.J. -- Neurology and neurologists during the Franco-Prussian War (1870-1871) / Walusinski, O. -- Silas Weir Mitchell : neurologists and neurology during the American Civil War / Boller, F., Birnbaum, .D -- Fench neurologists during World War I / Walusinski, O., Tatu, L., Bogousslavsky, J. -- Nostalgia in the army (17th-19th centuries) / Battesti, M. -- Neuropsychiatric disturbances, self-mutilation and malingering in the French armies during World War I : war strain or cowardice? / Tatu, L., Bogousslavsky, J. -- Neurological impact of World War I on the artistic avant-garde : the examples of André Breton, Guillaume Apollinaire and Blaise Cendrars / Bogousslavsky, J., Tatu, L. -- The central role of neuroscientists under National Socialism / Zeidman, L.A. -- What's in a name? : neurological eponyms of the Nazi era / Kondziella, D., Zeidman, L.A -- Neurology in the vietnam war / Gunderson, C.H., Daroff, R.B -- Neurotoxic weapons and syndromes / Carota, A., Calabrese, P., Bogousslavsky, J. -- Post-traumatic stress disorder among French armed forces members in Afghanistan : a new approach / Paul, F., Marimoutou, C., Pommier de Santi, Clervoy, P.

Prepared by specialty residents, fellows and staff in the Department of Medicine at Washington University School of Medicine, and reviewed by attending physicians in each field. Each volume in this renowned series delivers the on-the-spot help you need to provide quality patient management. Right from the initial chapter, you'll learn how to take a patient history, how to interpret exam findings, what tests to order, how to complete the workup, and how to formulate an effective management plan. The Second Edition of this reference continues to provide the practical, stepwise guidance from this manual and has been fully updated to include the most current diagnostic tests, workup tips, drugs and other therapeutic interventions available. NEW to the Second Edition: Updated content reflects the latest clinical advances and practice standards. New formatting follows consistent subheadings to make key facts easier to find. New chapters detail the latest diagnostic criteria, testing, and treatment options.

"Prepared by specialty residents, fellows and staff in the Department of Medicine at Washington University School of Medicine, and reviewed by attending physicians in each field-each volume in this renowned series delivers the on-thespot help you need to provide quality patient management. Right from the initial chapter, you'll learn how to take a patient history, how to interpret exam findings, what tests to order, how to complete the workup, and how to formulate an effective management plan. The Third Edition of this dynamic quick reference continues to provide the practical, stepwise guidance you've come to trust from The Washington Manual and has been fully updated to include the most current diagnostic tests, workup tips, drugs and other therapeutic interventions available"--

"Prepared by residents, fellows, and attending physicians at the Washington University School of Medicine, this handbook is a practical quick-reference guide to the diagnosis and treatment of cardiovascular diseases. It covers both inpatient and outpatient management approaches with the same front-lines practicality as the world-famous Washington Manual of Medical Therapeutics. Chapters include mnemonics, easily remembered bullet-point lists, bold-faced clinical pearls, and easy-to-read figures. This thoroughly revised, updated third edition emphasizes current guidelines from the American Heart Association and American College of Cardiology. Chapters cover new cardiac imaging modalities, peripheral vascular diseases, and cardiovascular diseases in specific patient populations, including women, the elderly, patients with HIV, and patients with diabetes. An appendix facilitates quick recall of the most common cardiovascular medications, common doses, and important side effects. The Washington Manual is a registered mark belonging to Washington University in St. Louis to which international legal protection applies. The mark is used in this publication by LWW under license from Washington University"--Provided by publisher.

"Several changes in content were made with the fourth edition. All chapters have been updated to provide the latest information on the pathophysiology and treatment of endocrine disorders. New chapters covering monogenic diabetes and transgender care have been added. Drug dosing information was also reviewed and updated in each chapter. Bulleted key points highlight the salient features of each chapter. Clinical pearls are highlighted in boldface text within the chapters"--Provided by publisher.

Hypothalamic and pituitary disorders -- Thyroid disorders -- Adrenal disorders -- Gonadal disorders -- Disorders of bone and mineral metabolism -- Disorders of fuel metabolism -- Neoplasms.

"Advances in the field of gastroenterology since the last edition of this manual have been incorporated into the chapters in this edition. The manual continues to provide succinct, precise recommendations on the evaluation and management of common gastrointestinal symptoms and disorders. Each chapter has been thoroughly revised, and some chapters have been rewritten, to update content to modern concepts and guidelines. The chapters were written predominantly by Washington University subspecialty fellows, with support and guidance from their faculty mentors. Similar to previous editions, the fourth edition of the manual is targeted to medical students, novice and advanced trainees, physician extenders, nurse practitioners, other health care providers, and physicians, and will provide easy access to clinically relevant recommendations for diagnosis and management of gastrointestinal disorders"-- Provided by publisher

Approach to the infectious disease consultation / Stephen Y. Liang, Michael J. Durkin, and Nigar Kirmani -- The acute febrile patient and sepsis / Yasir Hamad and Stephen Y. Liang -- Fever of unknown origin / Mohammad J. Saeed and Michael J. Durkin -- Bacteremia and infections of the cardiovascular system / Merilda Blanco and Michael J. Durkin -- Respiratory infections / Carlos Mejia-Chew and Michael A. Lane -- Infections of the gastrointestinal and hepatobiliary tract / Lemuel B. Non and Jennie H. Kwon -- Urinary tract infections / Juan J. Calix and Jeffrey P. Henderson -- Infections of the bone and joint / Shadi Parsaei and Stephen Y. Liang -- Skin and soft tissue infections / Darrell McBride and Stephen Y. Liang -- Central nervous system infections / Abdullah Aljorayid and Robyn S. Klein -- Sexually transmitted infections / Matifadza Hlatshwayo and Hilary Reno -- Human immunodeficiency virus infection / Jane O'Halloran and Rachel Presti -- Opportunistic infections associated with HIV / Jane O'Halloran and Gerome Escota -- Infection in non-HIV immunocompromised hosts / Anupam Pande and Ige George -- Dimorphic mycoses / Krunal Raval and Andrej Spec -- Zoonotic infections and ectoparasites / Abigail L. Carlson and Steven J. Lawrence -- Protozoal infections / Derek Yee and F. Matthew Kuhlmann -- Helminthic infections / Carlos Mejia-Chew and Philip Budge -- Infection prevention / Caline S. Mattar and Michael J. Durkin -- Antimicrobial agents / David J. Ritchie, Maren Cowley, and Nigar Kirmani -- Antimicrobial stewardship / Kevin Hsueh and Michael J. Durkin -- What was old is new again : arboviruses and hemorrhagic fevers / Michael Tang and Steven J. Lawrence

"Substantially revised since the previous edition, this Internship Survival Guide offers first-year residents practical, real-world medical and professional guidance from senior residents and faculty advisors at the Washington University School of Medicine. Advice is presented in a concise, bulleted format, lending itself to quick comprehension of the material. You'll learn the nuts and bolts of logistical issues and patient and colleague communication, as well as the basics of navigating your clinical rotations. To-the-point, updated explanations of the 10 most common diagnoses and patient complaints you'll encounter; includes key history, what not to miss, and when to call for help. Features a detachable pocket card with step-by-step instructions and full-color illustrations of basic procedures you need to master to pass residency requirements. Now with checklists--also on the pocket card--that serve as handy action items for interns. Includes helpful do's and don'ts on often overlooked workplace issues such as patient admission and discharges and communication with others on the medical team. Medical topics cover patient safety, risk mitigation, fluid management, operation of common devices like EKGs, as well as overviews of key clinical specialties. Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities! Read directly on your preferred device(s), such as computer, tablet, or smartphone. Customize for your language, including right-to-left reading, vertical writing, and enhanced annotation in over 30 languages. Easily convert to audiobook, powering your content with natural language text-to-speech. Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more"-- Provided by publisher. "This manual is written assuming knowledge of pathophysiology and data interpretation. The target audience is primarily those beginning their internship, but this guide may be useful for medical students, residents, and anyone else on the front lines of patient care"-- Provided by publisher.

"As an intern you will encounter many new challenges. These will range from very simple to most complex. Please remember that you have acquired the tools to address this adversity. And, even when you feel most overwhelmed, you are undoubtedly surrounded by a wealth of available resources that include ancillary and nursing staff, fellow interns, senior residents and attending physicians. Although the year ahead of you may now seem long and daunting, your tasks (other than survival) are quite achievable. The following competencies/milestones were copied from the curriculum for the in-patient general medicine rotation for the internship program at Washington University School of Medicine and Barnes-Jewish Hospital. You can see that not only are the objectives quite simple, but your rigorous work in medical school has well prepared you to master many of your goals. Throughout the year, use these objectives as a checklist to remind yourself of your accomplishments and to guide your learning in potential areas of weakness. - Patient care: o Gather accurate information about patients, including performing a thorough history and physical examination. o Synthesize data into a prioritized problem list and differential diagnosis, and then formulate diagnostic and therapeutic plans. o Prioritize each day's work. o Know the indications, contraindications, and risks of some invasive procedures and competently perform some invasive procedures"-- Provided by publisher.

Pt. I. General approach to kidney disease -- pt. II. Electrolytes and acid-base disorders -- pt. III. Acute kidney injury -- pt. IV. Glomerular diseases -- pt. V. Chronic kidney disease -- pt. VI. Miscellaneous renal disorders -- pt. VII. Renal replacement therapies and therapeutic plasma exchange -- pt. VIII. Drug dosing -- pt. IX. Transplant nethrology.

1. Central venous cannulation -- 2. Radial arterial line placement -- 3. Endotracheal intubation -- 4. Lumbar puncture -- 5. Abdominal paracentesis -- 6. Thoracentesis -- 7. Knee arthrocenetesis.

The skin exam / Rebecca Chibnall and Arthur Eisen -- Basic science of the skin / Karl Staser and Shadmehr Demehri -- Inflammatory disorders / Emily Beck and Sena Lee -- Infections and infestations / Heather Jones and Kara Sternhell-Blackwell -- Reactive disorders and drug eruptions / Shivani Tripathi and Milan Anadkat -- Disorders of pigmentation / Shaanan Shetty and Caroline Mann -- Benign skin lesions / Shayna Gordon and M. Laurin Council -- Malignant skin lesions / David Chen and Lynn Cornelius -- Disorders of the hair and nails / Katherine Moritz and Ann Martin -- Cutaneous manifestations of systemic disease / Urvi Patel and Amy Musiek -- Dermatologic surgery / Christopher Urban and Eva Hurst -- Pediatric dermatology / Kara Sternhell-Blackwell, Monique Kumar, and Susan Bayliss -- Geriatric dermatology / Kathleen Nemer and David Sheinbein -- Sun safety / Rachel Braden and Kimberly Brady -- Dermatologic therapies / Kyle Eash and Ian Hornstra -- Differential diagnoses appendices / Jamie Mull and M. Laurin Council.

1.Introduction to Echocardiographic Principles / Suzanne V. Arnold -- 2.The Comprehensive Transthoracic Echocardiographic Examination / David S. Raymer -- 3.The Role of Contrast in Echocardiography / Majesh Makan -- 4.Quantification of Left Ventricular Systolic and Diastolic Function / Christopher L. Holley -- 5.Right Ventricular Function and Pulmonary Hemodynamics / Nishath Quader -- 6.Stress Testing for Ischemia and Viability / Daniel H. Cooper -- 7.Ischemic Heart Disease and Complications of Myocardial Infarction / Michael Yeung -- 8.Cardiomyopathies / Christopher L. Holley -- 9.Hypertrophic Cardiomyopathy / Sharon Cresci -- 10.Aortic Valve Disease / Jacob S. Goldstein -- 11.Mitral Valve Disease / Nishath Quader -- 12.Pulmonic Valve / Julio E. Perez -- 13.Tricuspid Valve Disorders / Julio E. Perez -- 14.Evaluation of Prosthetic Valves / Jose A. Madrazo -- 15.Infective Endocarditis / Nishath Quader -- 16.Pericardial Disease and Cardiac Tamponade / Michael Yeung -- 17.Diseases of the Great Vessels: Aorta and Pulmonary Artery / Nishath Quader -- 18.Congenital Heart Disease / Majesh Makan -- 19.Cardiac Masses / Justin S. Sadhu -- 20.Cardiac Manifestations of Systemic Illness / Justin M. Vader -- 21.Transesophageal Echocardiography / Nishath Quader -- 22.Cardiac Devices in Heart Failure / Justin M. Vader.

Preoperative Evaluation and Care -- Intraoperative Considerations -- Common Postoperative Problems -- Nutrition -- Fluid, Electrolytes, and Acid-Base Disorders -- Hemostasis, Anticoagulation, and Transfusions -- Anesthesia -- Critical Care -- Trauma Resuscitation and Adjuncts -- Head, Neck, and Spinal Trauma -- Chest Trauma -- Abdominal Trauma -- Extremity Trauma -- Burns -- Wound Care -- Acute Abdomen -- Esophagus -- Stomach -- The Surgical Management of Obesity -- Small Intestine -- Surgical Diseases of the Liver -- Surgical Diseases of the Biliary Tree -- Pancreas -- Spleen -- Abdominal Transplantation -- Appendix -- Colon and Rectum -- Anorectal Disease -- Hernias -- Endoscopic, Laparoscopic, and Robotic Surgery -- Breast -- Skin and Soft Tissue Tumors -- Diseases of the Adrenal, Pituitary, and Hereditary Endocrine Syndromes -- Thyroid and Parathyroid Glands -- Lung and Mediastinal Diseases -- Cardiac Surgery -- Cerebrovascular Disease -- Thoracoabdominal Vascular Disease -- Peripheral Arterial Disease -- Venous and Lymphatic Disease -- Vascular Access -- Pediatric Surgery -- Otolaryngology for the General Surgeon -- Plastic, Reconstructive, and Hand Surgery -- Urology -- Obstetrics and Gynecology for the General Surgeon -- Radiology -- Biostatistics for the General Surgeon -- Patient Safety and Quality Improvement -- Answer Key.

"Although multivolume textbooks, as well as subspecialty texts, continue to have a central role in education and in everyday clinical practice, this manual is focused on meeting the immediate needs of an ever-accelerating world in which pathology residents and fellows never seem to have enough time to "get it all done," pathologists in practice never seem to be able to sign out cases quickly enough to satisfy their clinical colleagues, and their clinical colleagues themselves need a ready and available reference in surgical pathology when the pathologist is not immediately available. As with the first and second editions, it is our goal that this latest edition, continuing in the fast-access Washington Manual outline format, will fill this niche in our hectic world. A companion website offers the fully searchable text and an online image bank of over 2,800 fullcolor images (see the inside front cover for website access information)"--Provided by publisher.

This book provides a comprehensive, practical overview of cardiopulmonary exercise testing (CPET) suited for pulmonologists, cardiologists, anesthesiologists, and others with an interest in clinical exercise testing.

This book provides a comprehensive overview of the different water-associated infectious diseases and their linked pathogens with plausible strategies for their mitigation. Although we are in the era of 21st century having most of the advanced technologies at hand, yet water-associated infectious diseases are the major contributors towards the worldwide morbidity and mortality. The book also focuses on the various implementation strategies of sustainable hygienic conditions, discusses the robust, and reliable policies and strategies on a global aspect to provide unprivileged people access to the basic sanitation, hygiene and water. In addition, the book discusses the possible indirect effect of global warming on the spread of infectious diseases through the distribution of associated vectors.

This book discusses the water and carbon cycle system in the permafrost region of eastern Siberia, providing vital insights into how climate change has affected the permafrost environment in recent decades. It analyzes the relationships between precipitation and evapotranspiration, gross primary production and runoff in the permafrost regions, which differ from those intropical and temperate forests. Eastern Siberia is located in the easternmost part of the Eurasian continent, and the land surfacewith underlying permafrost has developed over a period of seventy thousand years. The permafrost ecosystem has specific hydrological and meteorological characteristics in terms of the water and carbon dynamics, and the current global warming and resulting changes in the permafrost environment are serious issues in the high-latitude regions. The book is a valuable resource for students, researchers and professionals interested in forest meteorology and hydrology, forest ecology, and boreal vegetation, as well as the impact of climate change and water-carbon cycles in permafrost and non-permafrost regions.

"Young Hiram Walker was born into bondage -- and lost his mother and all memory of her when he was a child -- but he is also gifted with a mysterious power. Hiram almost drowns when he crashes a carriage into a river, but is saved from the depths by a force he doesn't understand, a blue light that lifts him up and lands him a mile away. This strange brush with death forces a new urgency on Hiram's private rebellion. Spurred on by his improvised plantation family, Thena, his chosen mother, a woman of few words and many secrets, and Sophia, a young woman fighting her own war even as she and Hiram fall in love, he becomes determined to escape the only home he's ever known. So begins an unexpected journey into the covert war on slavery that takes Hiram from the corrupt grandeur of Virginia's proud plantations to desperate guerrilla cells in the wilderness, from the coffin of the deep South to dangerously utopic movements in the North. Even as he's enlisted in the underground war between slavers and the enslaved, all Hiram wants is to return to the Walker Plantation to free the family he left behind -- but to do so, he must first master his magical gift and reconstruct the story of his greatest loss." -- Provided by publisher.

The aim of this open access book is to provide a unique, timely, critical and comprehensive compilation of more than 30 years of robust international experimental and clinical research related to the basic science and therapeutic application of water-filtered infrared-A (wIRA) and hyperthermia in oncology, psychiatry (depression), musculoskeletal disorders, dermatology, infectiology, and surgery. This is an internationally absolutely unique attempt which publication is timely and of great interest in medical as well as in natural sciences. The aim is to enhance communication and advance the use of heat therapy for patient benefit, and to generate an environment in which anyone with an interest in hyperthermia can discuss, collaborate, network, and share events and resources. Productive dialogue and discussion among scientists and practitioners on issues relating to hyperthermia therapy is essential, especially relating to thermal transmission by water-filtered infrared-A (wIRA). The specificity and advantage of this technology is its tolerance by tissue, and its penetration of up to 3 cm allows the delivery of high heat dosages that are relevant across multiple clinical indications. Currently, wIRA is being applied in Austria, Germany, Portugal, Switzerland, The Netherlands, UK and the USA. The authors’ hope is that its use will increase in these countries, and also expand into others. This book will be an invaluable tool for oncologists, surgeons, dermatologists as well as physiotherapists.

This book discusses the production of bioethanol from water hyacinth, a potential source of lignocellulosic biomass. Biofuels, as an alternative to fossil fuels, not only ensure energy security but also mitigate air pollution and reduce greenhouse emissions. Biofuels can be produced from sugar- and starch-rich food crops (first-generation biofuel) or lignocellulosic biomass (second-generation biofuel). However, the overexploitation of conventional lignocellulosic sources such as agro-industrial residues, dedicated herbaceous, hardwoods and softwoods and forest residues may lead to problems in terms of land management and biodiversity conservation. Non-conventional sources include industrial cellulosic waste, municipal solid waste and weeds. Of these, weeds are an attractive lignocellulosic source due to their prevalence and easy availability. Eichhornia crassipes, commonly known as water hyacinth, is one of the world's most invasive weeds due to its rapid proliferation rate, efficient survival strategies in extreme conditions, and it has a significant impact on the environment, ecological communities, human health and socioeconomic development. Strategies including physical removal, chemical methods and biological control agents have proven inefficient in completely eradicating Eichhornia crassipes. On the other hand, water hyacinth has a low lignin and high holocellulose content and is a rich source of lignocellulosic biomass, and has therefore been exploited as a raw material for the production of biofuel, biogas, animal and fish feed, compost and other valuable products. Further, being an aquatic plant, it does not compete with food crops for land resources. The bioethanol-generating capacity of water hyacinth is comparable to that of agricultural waste, making it a potential raw material for biofuel production.

The contributed volume puts emphasis on a superior role of water in (bio)systems exposed to a mechanical stimulus. It is well known that water plays an extraordinary role in our life. It feeds mammalian or other organism after distributing over its whole volume to support certain physiological and locomotive (friction-adhesion) processes to mention but two of them, both of extreme relevance. Water content, not only in the mammalian organism but also in other biosystems such as whether those of soil which is equipped with microbiome or the ones pertinent to plants, having their own natural network of water vessels, is always subjected to a force field. The decisive force field applied to the biosystems makes them biomechanically agitated irrespective of whether they are subjected to external or internal force-field conditions. It ought to be noted that the decisive mechanical factor shows up in a close relation with the space-and-time scale in which it is causing certain specific phenomena to occur. The scale problem, emphasizing the range of action of gravitational force, thus the millimeter or bigger force vs. distance scale, is supposed to enter the so-called macroscale approach to water transportation through soil or plants' roots system. It is merely related to a percolation problem, which assumes to properly inspect the random network architecture assigned to the biosystems invoked. The capillarity conditions turn out to be of prior importance, and the porous-medium effect has to be treated, and solved in a fairly approximate way. The deeper the scale is penetrated by a force-exerting and hydrated agent the more non-gravitational force fields manifest. This can be envisaged in terms of the corresponding thermodynamic (non-Newtonian) forces, and the phenomena of interest are mostly attributed to suitable changes of the osmotic pressure. In low Reynolds number conditions, thus in the (sub)micrometer distance-scale zone, they are related with the corresponding viscosity changes of the aqueous, e.g. cytoplasmatic solutions, of semi-diluted and concentrated (but also electrolytic) characteristics. For example, they can be observed in articulating systems of mammals, in their skin, and to some extent, in other living beings, such as lizards, geckos or even insects. Through their articulating devices an external mechanical stimulus is transmitted from macro- to nanoscale, wherein the corresponding osmotic-pressure conditions apply. The content of the proposed work can be distributed twofold. First, the biomechanical mammalian-type (or, similar) systems with extraordinary relevance of water for their functioning will be presented, also including a presentation of water itself as a key physicochemical system/medium. Second, the suitably chosen related systems, mainly of soil and plant addressing provenience, will be examined thoroughly. As a common denominator of all of them, it is proposed to look at their hydrophobic and/or (de)hydration effects, and how do they impact on their basic mechanical (and related, such as chemo-mechanical or piezoelectric, etc.) properties. An additional tacit assumption employed throughout the monograph concerns statistical scalability of the presented biosystems which is equivalent to take for granted a certain similarity between local and global system's properties, mostly those of mechanical nature. The presented work's chapters also focus on biodiversity and ecological aspects in the world of animals and plants, and the related systems. The chapters' contents underscore the bioinspiration as the key landmark of the proposed monograph.

1.Introduction / Helen Bridle -- References -- 2.Overview of Waterborne Pathogens / Helen Bridle -- 2.1.Viruses -- 2.2.Bacteria -- 2.3.Protozoa -- 2.4.Helminths -- 2.5.Summary -- Acknowledgment -- References -- 3.Existing Methods of Waterborne Pathogen Detection / James Green -- 3.1.World health organisation guidelines -- 3.2.Types of monitoring -- 3.3.Fecal indicator monitoring -- 3.4.Direct detection of pathogens -- 3.5.Summary -- References -- 4.Sample Processing / Anna C. Schultz -- 4.1.Background -- 4.2.Sampling -- 4.3.Concentration techniques -- 4.4.Secondary concentration techniques -- 4.5.Nuclei acid extraction for molecular detection -- 4.6.Analytical controls -- 4.7.Summary -- References -- 5.Optical Detection Technologies for Waterborne Pathogens / Helen Bridle -- 5.1.Techniques using labeling -- 5.2.Spectroscopy -- 5.3.Summary -- References -- 6.Electrochemical Detection / Vincent Senez -- 6.1.Introduction -- 6.2.Potentiometry -- 6.3.Voltammetry -- 6.4.Coulometry -- 6.5.Impedance spectroscopy -- 6.6.Dielectrophoresis -- 6.7.Scaling effect -- 6.8.Miniaturized detection of waterborne pathogens -- 6.9.Summary and future outlook -- References -- 7.Biosensors for the Detection of Waterborne Pathogens / Marc Desmulliez -- 7.1.Performance characteristics -- 7.2.Recognition elements -- 7.3.Transduction methods -- 7.4.Biosensors for waterborne viruses -- 7.5.Biosensors for waterborne bacteria -- 7.6.Biosensors for waterborne protozoa -- 7.7.Biosensors for the detection of waterborne parasites -- 7.8.Summary and future outlook -- References -- 8.Molecular Methods for the Detection of Waterborne Pathogens / Kimberley Gilbride -- 8.1.Why molecular methods? -- 8.2.Molecular methods -- 8.3.Current state of pathogen detection in water sources -- 8.4.Fecal source tracking -- 8.5.Summary and future outlook -- References -- 9.Nanotechnology for Detection of Waterborne Pathogens / Helen Bridle -- 9.1.Introduction -- 9.2.Background -- 9.3.Nanotechnology in sample processing -- 9.4.Nanotechnology in pathogen detection -- 9.5.Summary -- References -- 10.Miniaturized Detection Systems / Helen Bridle -- 10.1.Microfluidics -- 10.2.Applications -- 10.3.Summary -- References -- 11.Applications of Emerging Technologies in the Drinking Water Sector / Graham Sprigg -- 11.1.Current position of the UK water industry -- 11.2.Application of WSPs and WSF in the rest of the world -- 11.3.The legislative framework -- 11.4.Pathogens of major concern to the market -- 11.5.Public health policy implications for detection and treatment -- 11.6.Detection and treatment from a market perspective -- 11.7.Market adoption of emerging technologies -- 11.8.Conclusions -- References -- 12.Conclusions / Helen Bridle -- 12.1.Summary -- 12.2.The future of waterborne pathogen monitoring.

We live in the age of the algorithm. Increasingly, the decisions that affect our lives -- where we go to school, whether we get a car loan, how much we pay for health insurance -- are being made not by humans, but by mathematical models. In theory, this should lead to greater fairness: Everyone is judged according to the same rules, and bias is eliminated. But as Cathy O'Neil reveals in this book, the opposite is true. The models being used today are opaque, unregulated, and uncontestable, even when they're wrong. Most troubling, they reinforce discrimination: If a poor student can't get a loan because a lending model deems him too risky (by virtue of his zip code), he's then cut off from the kind of education that could pull him out of poverty, and a vicious spiral ensues. Models are propping up the lucky and punishing the downtrodden, creating a 'toxic cocktail for democracy.' Welcome to the dark side of Big Data. Tracing the arc of a person's life, O'Neil exposes the black box models that shape our future, both as individuals and as a society. These 'weapons of math destruction' score teachers and students, sort résumés, grant (or deny) loans, evaluate workers, target voters, set parole, and monitor our health. O'Neil calls on modelers to take more responsibility for their algorithms and on policy makers to regulate their use. But in the end, it's up to us to become more savvy about the models that govern our lives.

"HRCT is an essential tool for evaluating patients w. diffuse pulmonary disease. It is commonly used to detect and characterize a variety of lung abnormalities"-- Provided by publisher.

Comprehensive, concise, and superbly illustrated, Weedon’s Skin Pathology Essentials, 3rd Edition, provides expert, easy-to-read guidance on key diagnoses in dermatopathology for pathologists and dermatologists in practice and training. This clearly written, well-structured text/atlas is ideal for quickly looking up practical problems in the recognition and diagnosis of skin lesions both clinically and histologically. Cross-referenced to the encyclopedic and authoritative Weedon’s Skin Pathology, 5th Edition, it enables you to avoid pitfalls and make the most accurate diagnoses with confidence.

Intro -- Preface -- Contents -- Part I: History and Scientific Overview of Weight Bearing Cone Beam Computed Tomography -- Chapter 1: Background of Weight Bearing Cone Beam Computed Tomography -- Introduction -- Weight Bearing CT International Study Group (WBCT ISG) -- International WBCT Society -- References -- Chapter 2: Scientific Overview of Weight Bearing Cone Beam Computed Tomography -- General Thoughts on Foot and Ankle Imaging -- Studies on Normal Controls -- Studies on Pathologic Conditions -- Radiographic Measurements Using Weight Bearing CT -- Future Directions Standardization of Measurements Using WBCT -- WBCT vs. Plain Films -- Conclusions -- References -- Part II: Scientific Background of Weight Bearing Cone Beam Computed Tomography -- Chapter 3: Weight Bearing CT Allows for More Accurate Bone Position (Angle) Measurement than Radiographs or CT -- Introduction -- Methods -- Inclusion and Exclusion Criteria: Ethics -- Image Acquisition -- Time Spent -- Angle Measurements -- Statistics -- Results -- Time Spent -- Angle Measurement: Differences Between Methods -- Angle Measurement: Intra- and Interobserver Reliability -- Discussion -- Time Spent Angle Measurement: Differences between Methods -- 1st-2nd Intermetatarsal Angle -- TMT Dorsoplantar -- TMT Lateral -- Hindfoot Angle -- Calcaneal Pitch Angle -- Angle Measurement: Intra- and Interobserver Reliability -- Shortcomings of the Study -- Radiation Dose -- Cost -- Approval for Use -- Standard Imaging? -- References -- Chapter 4: Combination of Weight Bearing CT (WBCT) with Pedography Shows No Statistical Correlation of Bone Position with Force/Pressure Distribution -- Introduction -- Methods -- Inclusion and Exclusion Criteria: Ethics -- Image Acquisition -- Pedography Measurements of Bone Position (Angles and Distances) -- Measurement of Pedographic Parameters -- Correlation Analysis of WBCT Parameters with Pedography Parameters -- Statistics -- Results -- Measurements of Bone Position (Angles and Distances): Intra- and Interobserver Reliability -- Correlation of WBCT Parameters with Pedography Parameters -- Discussion -- Angle Measurement: Intra- and Interobserver Reliability -- Correlation of WBCT Parameters with Pedography Parameters -- Shortcomings of the Study -- Radiation Dose -- References Chapter 5: Combination of Weight Bearing CT (WBCT) with Pedography Shows Relationship Between Anatomy-Based Foot Center (FC) and Force/Pressure-Based Center of Gravity (COG) -- Introduction -- Methods -- Inclusion and Exclusion Criteria, Ethics -- Image Acquisition: Foot Center (FC) -- Pedography: Center of Gravity (COG) -- Comparison of FC/COG -- Statistics -- Results -- Discussion -- Center of Gravity (COG) -- Foot Center (FC) -- Shortcomings of the Study -- Radiation Dose -- References -- Chapter 6: A New Concept of 3D Biometrics for Hindfoot Alignment Using Weight Bearing CT -- Introduction

The use of legislative and other controls on animal research to meet public expectations and improve animal welfare -- Animal rights and animal welfare : philosophy and science -- Species choice and animal welfare -- The harm/benefit judgement -- Improving the welfare of animals used in research : the 3Rs -- Science and animal welfare : a partnership.

This book investigates how fish experience their lives, their amazing senses and abilities, and how human actions impact their quality of life. The authors examine the concept of fish welfare and the scientific knowledge behind the inclusion of fish within the moral circle, and how this knowledge can change the way we treat fish in the future. In many countries fish are already protected by animal welfare legislation in the same way as mammals, but in practice there is still a major gap between how we ethically view these groups and how we actually treat them. The poor treatment of fish represents a massive animal welfare problem in aquaculture and fisheries, both in terms of the number of animals affected and the severity of the welfare issues. Thanks to its interdisciplinary scope, this thought-provoking book appeals to professionals, academics and students in the fields of animal welfare, cognition and physiology, as well as fisheries and aquaculture management.

This book is devoted to the welfare of invertebrates, which make up 99% of animal species on earth. Addressing animal welfare, we do not often think of invertebrates; in fact we seldom consider them to be deserving of welfare evaluation. And yet we should. Welfare is a broad concern for any animal that we house, control or utilize - and we utilize invertebrates a lot. The Authors start with an emphasis on the values of non-vertebrate animals and discuss the need for a book on the present topic. The following chapters focus on specific taxa, tackling questions that are most appropriate to each one. What is pain in crustaceans, and how might we prevent it? How do we ensure that octopuses are not bored? What do bees need to thrive, pollinate our plants and give us honey? Since invertebrates have distinct personalities and some social animals have group personalities, how do we consider this? And, as in the European Unions application of welfare consideration to cephalopods, how do the practical regulatory issues play out? We have previously relegated invertebrates to the category 'things and did not worry about their treatment. New research suggest that some invertebrates such as cephalopods and crustaceans can have pain and suffering, might also have consciousness and awareness. Also, good welfare is going to mean different things to spiders, bees, corals, etc. This book is taking animal welfare in a very different direction. Academics and students of animal welfare science, those who keep invertebrates for scientific research or in service to the goals of humans, as well as philosophers will find this work thought-provoking, instructive and informative.

This book provides a multidisciplinary overview of the impact of human-animal interaction on well-being from childhood to later life. It presents a life course perspective to the study of human-animal interaction, addressing concepts of family and the role of pets therein, as well as the impact of companion animals on child development and successful aging. This book fills a gap in the existing literature by framing the study of human-animal interaction, including the role of animal-assisted interventions on well-being, in a broader social and behavioral context.

The development -- The philosophy student and the pursuit of a well-being enhancing strategy -- The process of validation of well-being therapy -- Initial evaluation -- Session 1 -- Session 2 -- Session 3 -- Session 4 -- Session 5 -- Session 6 -- Session 7 -- Session 8 -- The four-session-program -- Depression -- Mood swings -- Generalized anxiety disorder -- Panic and agoraphobia -- Post-traumatic stress disorder -- Children and adolescents -- New directions -- Going further.

This book represents a daring and rarely attempted endeavor to bridge the gap between histopathology and molecular medicine in that cutting-edge molecular findings are seamlessly integrated into the key morphological features. This volume also includes discussions of short lists of organ-based benign lesions with concerning morphological features. Presented in the differential diagnosis section, they will not only serve as useful checklists for the surgical pathologist who is seriously contemplating a diagnosis of malignancy due to the observation of some cytological or histological atypia, but also help hone the key features of each malignant atypia. Well-Differentiated Malignancies: New Perspectives provides an innovative resource on the difficult topic of well-differentiated malignancies for pathology residents, fellows and for those already in clinical practice.

"An inspiring collection of essays by black women writers, curated by the founder of the popular book club Well-Read Black Girl, on the importance of recognizing ourselves in literature. Remember that moment when you first encountered a character who seemed to be written just for you? That feeling of belonging remains with readers the rest of their lives--but not everyone regularly sees themselves on the pages of a book. In this timely anthology, Glory Edim brings together original essays by some of our best black women writers to shine a light on how important it is that we all--regardless of gender, race, religion, or ability--have the opportunity to find ourselves in literature. Contributors include Jesmyn Ward (Sing, Unburied, Sing), Lynn Nottage (Sweat), Jacqueline Woodson (Another Brooklyn), Gabourey Sidibe (This Is Just My Face), Morgan Jerkins (This Will Be My Undoing), Tayari Jones (An American Marriage), Rebecca Walker (Black, White and Jewish), and Barbara Smith (Home Girls: A Black Feminist Anthology). Whether it's learning about the complexities of femalehood from Zora Neale Hurston and Toni Morrison, finding a new type of love in The Color Purple, or using mythology to craft an alternative black future, the subjects of each essay remind us why we turn to books in times of both struggle and relaxation. As she has done with her book club-turned-online community Well-Read Black Girl, in this anthology Glory Edim has created a space in which black women's writing and knowledge and life experiences are lifted up, to be shared with all readers who value the power of a story to help us understand the world and ourselves."--Publisher information.

This book provides a detailed guide for surgeons and surgical trainees on a variety of facets relevant to wellbeing, and how to maintain wellbeing throughout a career in academic surgery. Individual and external factors relevant to wellbeing are both covered in relation to the surgeon. Aspects covered include healthcare roles, personal factors, socio-cultural factors, the regulatory business, and payer environment. Potential strategies for managing welfare including considerations for both students and residents are provided, as are methodologies for studying aspects of wellbeing. Wellbeing offers a practical and personal insight on maintaining wellbeing in academic surgery and is a valuable resource for all practicing and trainee surgeons across a variety of disciplines, as well as those who are interested in studying factors affecting the wellbeing of surgical specialists.

"The most comprehensive textbook on the thyroid appears in an extensively revised 10th edition. This classic text provides comprehensive coverage of every aspect of thyroid anatomy, development, biochemistry, physiology, pathophysiology, and treatment of all thyroid disorders. This edition has a more international group of contributors and new chapters on surgical management of thyroid cancer, thyroid disrupters and thyroid hormone analogs. Chapters address clinical controversies regarding subclinical hypothyroidism and hyperthyroidism"--Provided by publisher.

"The first edition of The Thyroid, conceived by Dr. Sidney Werner who believed, and we agree, that a comprehensive clinical and basic textbook devoted to the thyroid was needed, was first published in 1955 and again in 1962"-- Provided by publisher.

"West's Pulmonary Pathophysiology: The Essentials offers accessible explanations of disease processes that affect the respiratory system. This best-selling companion to West's Respiratory Physiology, Tenth Edition, has served generations of students. Dr. John B. West, together with new co-author Dr. Andrew M. Luks, presents the vital knowledge you need in a concise, straightforward manner that's easy to understand."--Publisher.

Structure and function -- Ventilation -- Diffusion -- Blood flow and metabolism -- Ventilation-perfusion relationships -- Gas transport by the blood -- Mechanics of breathing -- Control of ventilation -- Respiratory system under stress -- Tests of pulmonary function.

Early days of blotting / Edwin Southern -- Origins of protein blotting / Harry Towbin -- Western blotting : remembrance of things past / W. Neal Burnette -- Simian virus 40 and protein transfer / Jaime Renart -- Western blotting : an introduction / Biji T. Kurien and R. Hal Scofield -- From little helpers to automation / Biji T. Kurien and Harry Towbin -- Spectrophotometric methods to determine protein concentration / J. P. Dean Goldring -- Solubilization of proteins : the importance of lysis buffer choice / Mandy Peach [and three others] -- Simultaneous immunoblotting analysis with activity gel electrophoresis and 2-D gel electrophoresis / Der-Yen Lee and Geen-Dong Chang -- Diffusion blotting : a rapid and simple method for production of multiple blots from a single gel / Ingrid Olsen and Harald G. Wiker -- Multiple immunoblots by passive diffusion of proteins from a single SDS-PAGE gel / Biji T. Kurien and R. Hal Scofield -- Slice blotting / Graeme Lowe -- Localizing proteins by tissue printing / Rafael F. Pont-Lezica -- Dot-immunobinding assay (Dot-Iba) / Sumi Surendran, Annamma Mathai, and Vishnampet Venkataraman Radhakrishnan -- Analysis of antibody clonotype by affinity immunoblotting / Biji T. Kurien and R. Hal Scofield -- Glycosaminoglycan blotting and detection after electrophoresis separation / Nicola Volpi and Francesca Maccari -- Well-based reverse-phase protein array of formalin- fixed paraffin-embedded tissue / Joon-Yong Chung and Stephen M. Hewitt -- Quantitative computerized western blotting in detail / Dalit Talmi-Frank, Charles L. Jaffe, and Gad Baneth -- Cationic electrophoresis and eastern blotting / Engelbert Buxbaum -- Miniaturized blotting system for simultaneous detection of different autoantibodies / Ulrich Canzler [and eight others] -- Proteomic expressional profiling of a paraffin-embedded tissue by multiplex tissue immunoblotting / Joon-Yong Chungand Stephen M. Hewitt -- Post-staining electroblotting for efficient and reliable peptide blotting / Der-Yen Lee and Geen-Dong Chang -- Multistrip western blotting : a tool for comparative quantitative analysis of multiple proteins / Edita Aksamitiene, Jan B. Hoek, and Anatoly Kiyatkin -- Western blotting using PVDF membranes and its downstream applications / Setsuko Komatsu -- Blotting from phastGel to membranes by ultrasound / Joseph Kost and Aharon Azagury -- Western blotting of high and low molecular weight proteins using heat / Biji T. Kurien and R. Hal Scofield -- Membrane strip affinity purification of autoantibodies / Biji T. Kurien -- Strip immunoblotting of multiple antigenic peptides / Biji T. Kurien -- Double-blotting : a solution to the problem of nonspecific binding of secondary antibodies in immunoblotting procedures / Françoise Lasne -- Method for resolution and western blotting of very large proteins using agarose electrophoresis / Marion L. Greaser and Chad M. Warren -- Immunodetection of P-selectin using an antibody to its C-terminal tag / Padmaja Mehta-D'souza -- Improvements and variants of the multiple antigen blot assay-MABA : an immunoenzymatic technique for simultaneous antigen and antibody screening / Oscar Noya [and six others] -- Blotting from immobilized pH gradient gels : application to total cell lysates / Harry Towbin -- Immunoprecipitation : western blot for proteins of low abundance / Edward P. Trieu and Ira N. Targoff -- Native electrophoresis and western blot analysis (NEWeB) : methods and applications / Ioannis N. Manoussopoulos and Mina Tsagris -- Shift-western blotting : separate analysis of protein and DNA from protein-DNA complexes / Matthias Harbers -- Grid-immunoblotting / Olga Yeliosof and R. Hal Scofield -- Detection and quantification of protein-protein interactions by far-western blotting / Joshua A. Jadwin, Bruce J. Mayer, and Kazuya Machida -- Western blot analysis of adhesive interactions under fluid shear conditions : the blot rolling assay / Robert Sackstein and Robert Fuhlbrigge -- Centrifuge blotting / Jinny Paul -- Blotting of coomassie blue-stained proteins from PAGE gels to transparencies / Jinny Paul -- B-cell ELISPOT : for the identification of antigen-specific antibody-secreting cells / Hemangi B. Shah and Kristi A. Koelsch -- T cell ELISPOT : for the identification of specific cytokine-secreting T cells / Kerry M. Leehan and Kristi A. Koelsch -- Membrane microplates for one- and two-color ELISPOT and FLUOROSPOT assays / Alexander E. Kalyuzhny -- SDS-PAGE to immunoblot in one hour / Biji T. Kurien [and three others] -- Single-cell western blotting / Syed M. S. Quadri -- Protein detection by simple western analysis / Valerie M. Harris -- Western blotting using microfluidics / Pothur R. Srinivas -- Two-dimensional gel-based protein standardization verified by western blot analysis / Hisao Haniu [and three others] -- Fingerprint deposition on nitrocellulose and polyvinylidene difluoride membranes using alkaline phosphatase / Biji T. Kurien, Debashish Danda, and R. Hal Scofield -- Other notable protein blotting methods : a brief review / Biji T. Kurien and R. Hal Scofield.

Western Blotting Guru provides researchers in molecular biology with a handy reference for approaching and solving challenging problems associated with immunoblotting setup and optimization. As a laboratory guide, it emphasizes the technical aspects of efficiently employing immunoblotting as a tool in molecular biology laboratories. The book covers the basic science underlying immunoblotting and detailed description of the method parameters, followed by good benchtop practices, tips and tricks for obtaining high-quality data and a detailed troubleshooting guide addressing a variety of problem types.

This volume explores major wetland ecosystem services, such as climate cooling and water quality improvement, and discusses the recent wetland conservation and restoration activities in China and neighboring countries. The role of wetlands in either cooling or warming the climate is analyzed as the net balance between carbon sequestration and emissions of methane and nitrous oxide. Wetlands start off having a net warming effect on the climate but in time switch to net cooling. Further, they remove 40% of the N and P from run-off and groundwater flow in agricultural areas, but wetlands need to amount to 10% of the total catchment area to make a difference. Reflecting on the recent large investment in wetland ecological studies in China and neighboring countries, the book addresses invasive species in coastal wetlands as well as the protection and wise use of tidal flats around the Yellow Sea. It also presents promising regional case studies on wetland restoration. The book is intended for academics, students and practitioners in the field of wetland ecology, management and restoration, as well as consultants and professionals working in conservation, wise use and environmental policy.

Based on actual data of Soviet whaling, and reliable methodologies that existed at the time when this monograph was written, it examines the distribution and migration patterns of whales of the Southern Ocean. It defines distinct populations on the basis of phenes, as well as whale breeding zones, which are located in the adjacent to the Southern Ocean waters at lower latitudes. The book records the presence of a new species of killer whale in the Southern Ocean--Orcinus nana. Prenatal growth patterns, pregnancy and lactation duration, mean sizes of new-born whales are determined. Methods for the graphic recording of registering structures are described, and an original method for their decoding is proposed to determine animal age. The age of sexual and physical maturity, life expectancy is determined. Earlier unknown "pair formations" on the lower jaw of baleen whales and sperm whales are described, together with their macro, histological and electronic microscopic structure. The impact of the extermination of whales on the Southern Ocean ecosystem is examined, recommendations for control of the current state of whale populations are given, and perspectives of whale population recovery are estimated. Regions that could be used as testing areas for whale registration method are defined. The book is intended for biologist-cytologists, ecologists and other specialists interested in cetaceans, and for biology students.

With more than 10 million copies sold in 28 countries, the world's most popular job-search book is updated for 2020, tailoring Richard Bolles's long-trusted guidance with up-to-the-minute information and advice for today's job-hunters and career-changers. What Color Is Your Parachute? is the world's most popular job-hunting guide, revised and updated annually with more than ten million copies sold. This newly streamlined edition features the latest resources, case studies, and perspectives on today's job market, revealing surprising advice on what works--and what doesn't--so you can focus your efforts on tactics that yield results. At its core is Richard N. Bolles's famed Flower Exercise, a unique self-inventory that helps you design your career--and your life--around your key passions, transferable skills, traits, and more. This practical manual also provides essential tips for writing impressive resumes and cover letters, networking effectively, interviewing with confidence, and negotiating the best salary possible. Whether you're searching for your first job, were recently laid off, or are dreaming of a career change, What Color Is Your Parachute? will guide you toward a fulfilling and prosperous life's work.

"By shedding light on how doctors cope with the stresses and responsibilities of patients, colleagues, lawyers, and their personal lives, she explains why it is important that patients know how emotions influence the way physicians treat their patients both medically and interpersonally. Exploring the full range of human emotion--from the fear of making a fatal mistake to the pride and elation of triumphing over death, What Doctors Feel allows patients at the other end of the stethoscope to have a good listen to the beat of the emotional life behind the white coat."--Beacon Press.

About Medical Writers and Writing -- Getting Started in Medical Writing -- The Process of Medical Writing -- Medical Writing Pointers and Pitfalls -- Getting Your Work in Print -- Ethical Issues in Medical Writing -- Remarkable Medical Writing -- Backstories of Medical Writers and Writing -- What Writers Say about Writing -- A Writer?s Attic -- Web Sites: The Medical Writer?s Guide to the Internet -- Recommended Reading for the Serious Medical Writer.

"A searing memoir of reckoning and healing from an acclaimed journalist and former This American Life producer investigating the little-understood science behind Complex PTSD and how it has shaped her life. By age thirty, Stephanie Foo was successful on paper: She had her dream job as a radio producer at This American Life and had won an Emmy. But behind her office door she was having panic attacks and sobbing at her desk. After years of questioning what was wrong with her, she was diagnosed with Complex PTSD-a condition that occurs when trauma happens continuously, over the course of years. Both of Stephanie's parents had abandoned her as a teenager after years of physical and verbal abuse and neglect. She thought she'd overcome her trauma, but her diagnosis illuminated the ways in which her past continued to threaten her health, her relationships, and her career. Finding few resources to help her heal, Stephanie set out to map her experience onto the scarce scientific research on C-PTSD. In this deeply personal and thoroughly researched account, Stephanie interviews scientists and psychologists and tries a variety of innovative therapies with the determination and curiosity of an award-winning journalist. She returns to her hometown of San Jose, California, to investigate the effects of immigrant trauma on a community, she uncovers family secrets in the country of her birth, Malaysia, and learns how trauma can be inherited through generations. Ultimately, she discovers that you don't move on from trauma-but you can learn to move with it, with grace and joy. Powerful, enlightening, and clarifying, What My Bones Know is a brave narrative that reckons with the hold of the past over the present, the mind over the body-and one woman's ability to reclaim agency from her trauma"-- Provided by publisher.

Being a patient is a unique interpersonal experience but it is also a universal human experience. The relationships formed when we are patients can also teach some of life's most important lessons, and these relationships provide a special window into ethics, especially the ethics of healthcare professionals. This book answers two basic questions: As patients see it, what things allow relationships with healthcare providers to become therapeutic? What can this teach us about healthcare ethics? This volume presents detailed descriptions and analyses of 50 interviews with 58 patients, representing a wide spectrum of illnesses and clinician specialties. The authors argue that the structure, rhythm, and horizon of routine patient care are ultimately grounded in patient vulnerability and clinician responsiveness. From the short interview segments, the longer vignettes and the full patient stories presented here emerge the neglected dimensions of healthcare and healthcare ethics. What becomes visible is an ethics of everyday interdependence, with mutual responsibilities that follow from this moral symbiosis. Both professional expressions of healthcare ethics and the field of bioethics need to be informed and reformed by this distinctive, more patient-centered, turn in how we understand both patient care as a whole and the ethics of care more specifically. The final chapters present revised codes of ethics for health professionals, as well as the implications for medical and health professions education.

This book is an introduction to chest radiology, specifically designed for the needs of first-year residents. On the first rotation in chest imaging, radiology residents are asked to learn significant amounts of information at a fast and unrelenting pace. However, most current books are densely written and contain far more material than residents need to know. Moreover, the number, variety, and quality of images is often limited. What Radiology Residents Need to Know: Chest Radiology answers these needs by presenting the important information in bullet fashion, divided into convenient sub-units, such as "clinical information," "imaging findings," and "management." In most cases, an individual pathological condition can be presented in one page or less. This volume covers such topics as volume loss, pneumonia, pulmonary edema, inhalation diseases, and pulmonary, mediastinal, and pleural tumor imaging. In addition, it contains tips on approaching and interpreting chest radiographs and CT based on decades of practical experience and teaching residents at the work station. With liberal use of images and an online image bank with high-quality images, this book gives readers a comprehensive library of chest imaging scans and serves as an ideal guide for radiology residents.

This book is an introduction to musculoskeletal radiology, specifically designed for the needs of first-year residents. On the first rotation in musculoskeletal imaging, radiology residents are asked to learn significant amounts of information at a fast and unrelenting pace. However, most current books are densely written and contain far more material than residents need to know. Moreover, the number, variety and quality of images is often limited. What Radiology Residents Need to Know: Musculoskeletal Radiology answers these needs by presenting the important information in bullet fashion, divided into convenient sub-units, such as "clinical information," "imaging findings," and "management." In most cases, an individual pathological condition can be presented in one page or less. In addition, it contains tips on approaching and interpreting radiographs, MRI and CT based on decades of practical experience and teaching residents at the work station. With liberal use of illustrations in the text and an online bank of many more high-quality images, this book gives readers a comprehensive library of musculoskeletal imaging scans and serves as an ideal guide for radiology residents.

The purpose of this book is twofold: First, it provides an up-to-date overview of the field of surgical oncology for surgeons in training. Particular attention is devoted to the principles of surgery, but important aspects of radiation and medical oncology are also discussed. Furthermore, diagnostic, staging, and treatment algorithms are presented that will offer invaluable assistance in management decision making. The second aim of the book is to offer a comprehensive reference source on the role of surgery in curative and palliative management for medical and radiation oncologists (in practice and in training) and other healthcare professionals involved in the care of cancer patients. The full range of cancer types is covered in a practical, multidisciplinary approach, and additional chapters are devoted to pediatric malignancies, the role of new surgical technologies, and surgical emergencies.

"The dramatic story of the signature environmental disaster of our time and an inspiring tale of scientific resistance by a relentless physician who stood up to power. Flint was already a troubled city in 2014 when the state of Michigan--in the name of austerity--shifted the source of its water supply from Lake Huron to the Flint River. Soon after, citizens began complaining about the water that flowed from their taps--but officials rebuffed them, insisting that the water was fine. Dr. Mona Hanna-Attisha, a pediatrician at the city's public hospital, took state officials at their word and encouraged the parents and children in her care to continue drinking the water--after all, it was American tap water, blessed with the state's seal of approval. But a conversation at a cookout with an old friend, leaked documents from a rogue environmental inspector, and the activism of a concerned mother raised red flags about lead--a neurotoxin whose irreversible effects fall most heavily on children. Even as circumstantial evidence mounted and protests grew, Dr. Mona knew that the only thing that could stop the lead poisoning was undeniable proof--and that to get it, she'd have to enter the fight of her life. What the Eyes Don't See is the inspiring story of how Dr. Mona--accompanied by an idiosyncratic team of researchers, parents, friends, and community leaders--proved that Flint's kids were exposed to lead and then fought her own government and a brutal backlash to expose that truth to the world. Paced like a scientific thriller, this book shows how misguided austerity policies, the withdrawal of democratic government, and callous bureaucratic indifference placed an entire city at risk. And at the center of the story is Dr. Mona herself--an immigrant, doctor, scientist, and mother whose family's activist roots inspired her pursuit of justice. What the Eyes Don't See is a riveting, beautifully rendered account of a shameful disaster that became a tale of hope, the story of a city on the ropes that came together to fight for justice, self-determination, and the right to build a better world for their--and all of our--children."--Jacket

"What We Bring to the Practice of Medicine brings together a collection of short essays from women physicians working in diverse fields of medicine around the world. Through compassion, humor, and resiliency, their stories reveal the truth of what life is like for a variety of women in medicine. While men and women physicians face different challenges and bring different historical experiences to the examination table, the history of medicine has been primarily told by men. Doctors Kimberly Greene-Liebowitz and Dana Corriel compile the pieces in this collection to highlight the many topics of concern for women physicians--some of which may be unknown to medical field outsiders. Topics include the physician-patient relationship, mastery of clinical practice, barriers to career advancement and success, and the challenge of balancing a demanding professional life with domestic responsibilities, an issue brought to the fore by the COVID-19 pandemic. What We Bring to the Practice of Medicine showcases the experiences of women physicians at every stage of their careers as well-from the beginning of medical school to the brink of retirement. These 40 essays are an expansive, unprecedented examination of what drives clinical and personal decisions and demonstrate how a physician's character is intricately intertwined with their approach to caregiving and the practice of medicine"-- Provided by publisher.

Raised in America, the multiracial daughter of a mother from Johannesburg struggles with her mother's terminal cancer, her own need to find love, and unexpected motherhood.

"Designed and organized to answer the most common questions that patients have about their psychiatric medications, What Your Patients Need to Know About Psychiatric Medications, Third Edition, emphasizes clarity, accuracy, and accessibility of information. From Valium and Ativan to Prozac and Adderall, more than 70 medications from all of the major classes are discussed under eight key sections."--Back cover.

This book presents recent advances in global wheat crop research, including the effects of abiotic stresses like high and low temperatures, drought, hypoxia, salinity, heavy metals, nutrient deficiency, and toxicity on wheat production. It also highlights various approaches to alleviate the damaging effects of abiotic stress on wheat as well as advanced approaches to develop abiotic-stress-tolerant wheat crops. Wheat is probably one of the worlds most important cereals; it is a staple food in more than 40 countries, and because of its adaptability is cultivated in almost every region. Global wheat production has more than doubled in the last 50 years due to higher yields. However, despite their high yield potential, modern wheat cultivars are often subject to crop loss due to the abiotic stresses. As such, plant breeders have long aimed to improve tolerance in order to maintain yield. Written by 85 experts, and offering the latest insights into wheat responses and tolerance to various abiotic stresses, it is a valuable tool for agronomists, plant breeders, plant physiologists and students in the field of plant science and agriculture. It is the first book to comprehensively cover past and current abiotic stress problems and tolerance mechanisms.

This book is about three inflammatory conditions that underlie wheat sensitivities caused by the consumption of wheat and related cereals. The book describes, discusses and differentiates celiac disease, amylase trypsin inhibitor (ATI) sensitivity, and the wide spectrum of wheat allergies, especially a novel, but highly common atypical wheat allergy. The mechanisms of the three wheat sensitivities along with their clinical characteristics, and their their state-of-the art diagnosis and therapy are thoroughly described. This is accompanied by commented case reports. The book is well structured and illustrated with numerous easy-to-grasp yet scientifically updated sketches. The novelty, immunological insight and praxis relevance for specialists as well as patients and interested laypeople makes this book appealing to a broad readership. Written by an internationally distinguished scientist and clinician in food and wheat related diseases, this book is intended for GPs, internists, gastroenterologists, rheumatologists and immunologists, as well as dieticians, researchers and especially patients who might be affected by these sensitivities.

Take a simple approach to understanding the fundamentals with Wheater's Functional Histology. Offering concise text accompanied by hundreds of captions and images of histology slides, this best-selling textbook will equip you with all the must-know histology information you need to complete your courses and ace your exams. Recognize the microscopic structure of normal human tissues and how it relates to function with the help of over 900 high-quality histology images and illustrations.Master how to apply histology in a clinical context through coverage of common clinical conditions in each chapter.Access the entire contents online at Student Consult, including all of the images, a virtual histolab, and USMLE-style self-assessment questions and rationales.