BookIsabel Sá-Correia, editor.
Summary: This book discusses genome-based strategies to provide a holistic understanding of yeasts in Human Health and as model organisms in basic research or industrial production. Using numerous Saccharomyces cerevisiae strains and various non-conventional yeast species isolated from diverse origins, it describes essential biological processes, the biotechnological exploitation of yeast and pathogenesis control. It also demonstrates how functional and comparative genomics and the development of genome engineering tools are used in modern yeast research. The use of yeasts as experimental eukaryotic models increasingly gained prominence when several Nobel Prizes in Physiology/Medicine and Chemistry were awarded for innovative research, using yeast strains to elucidate molecular mechanisms in a wide range of human physiological processes and diseases, such as autophagy, cell cycle regulation and telomerase activity. This book offers useful insights for scientists in yeast research, clinical scientists working with yeast infectious models and for industrial researchers using applied microbiology.
Contents:
Physiological Genomics of Multistress Resistance in the Yeast Cell Model and Factory : Focus on MDR/MXR Transporters / Cláudia P. Godinho and Isabel Sá-Correia
Mechanisms of Yeast Adaptation to Wine Fermentations / Estéfani García-Ríos and José Manuel Guillamón
Development of Robust Yeast Strains for Lignocellulosic Biorefineries Based on Genome-Wide Studies / Ming-Ming Zhang, Hong-Qi Chen, Pei-Liang Ye, Songsak Wattanachaisaereekul, Feng-Wu Bai and Xin-Qing Zhao
Physiological Genomics of the Highly Weak-Acid-Tolerant Food Spoilage Yeasts of Zygosaccharomyces bailii sensu lato / Margarida Palma and Isabel Sá-Correia
Yeast Genome-Scale Metabolic Models for Simulating Genotype-Phenotype Relations / Sandra Castillo, Kiran Raosaheb Patil and Paula Jouhten
Emerging Mechanisms of Drug Resistance in Candida albicans / Rajendra Prasad, Remya Nair and Atanu Banerjee
Genome-Wide Response to Drugs and Stress in the Pathogenic Yeast Candida glabrata / Pedro Pais, Mónica Galocha and Miguel Cacho Teixeira
Lipidomics Approaches : Applied to the Study of Pathogenesis in Candida Species / Ashutosh Singh, Nitesh Kumar Khandelwal and Rajendra Prasad
Yeast at the Forefront of Research on Ageing and Age-Related Diseases / Belém Sampaio-Marques, William C. Burhans and Paula Ludovico.