Bookeditors, Mansoor M. Amiji, PhD, RPh, Distinguished Professor and Chairman,
... Show More Department of Pharmaceutical Sciences, Director, Laboratory of Biomaterials and Advanced Nano-Delivery Systems (BANDS), School of Pharmacy, Bouve College of Health Sciences, Northeastern University, Boston, Massachusetts, Thomas J. Cook, PhD, RPh, Director of Program Assessment, Associate Professor, Department of Pharmaceutical and Biomedical Sciences Touro College of Pharmacy, New York, New York, W. Cary Mobley, PhD, RPh, Clinical Associate Professor, Department of Pharmaceuticals, University of Florida, College of Pharmacy, Gainesville, Florida.
Summary: This book explores the fundamental physicochemical properties and processes important for understanding how drugs are transformed into usable and stable drug products that release their drug upon administration, and for understanding the different processes that the released drug may encounter on its way to its pharmacological target prior to being eliminated by the body.... The book concludes with an overview of the principles of kinetics that are essential to understanding the rates at which many of the processes discussed in previous chapters occur.
Contents:
States of matter related to pharmacuetical formulations / Beverly J. Sandmann, Ann Newman, and Gregory T. Knipp
Physical properties of solutions / Beverly Sandmann, Antoine Al-Achi, Robert Greenwood
Ionic equilibria and buffers / Beverly Sandmann, Alekha K. Dash, Antoine Al-Achi, Robert Greenwood
Solubility, dissolution, and partitioning/ Beverly J. Sandmann and Mansoor M. Amiji
Mass transport / Mansoor M. Amiji
Complexation and protein binding / Mansoor M. Amiji
Dispersed systems / W. Cary Mobley
Interfacial phenomena / Maria Polikandritou Lambros and Shihong Li Nocolaou
Rheology / Maria Polikandritou Lambros
Chemical kinetics of pharmaceuticals / Thomas J. Cook.