Books

Contents:
Chapter 1. Importing and exporting data
Chapter 2. Manipulating data
Chapter 3. Statistical analyses
Chapter 4. Graphics
Chapter 5. R.

Contents:
Rab family of GTPases / Guangpu Li and M. Caleb Marlin
Bioinformatic approaches to identifying and classifying Rab proteins / Yoan Diekmann and José B. Pereira-Leal
Rab-NANOPS : FRET biosensors for Rab membrane nanoclustering and prenylation detection in mammalian cells / Arafath Kaja Najumudeen ... [et al.]
High-throughput assay for profiling the substrate specificity of Rab GTPase-activating proteins / Ashwini K. Mishraand David G. Lambright
Measuring Rab GTPase-activating protein (GAP) activity in live cells and extracts / Ryan M. Nottingham and Suzanne R. Pfeffer
Analysis of the interactions between Rab GTPases and class V myosins / Andrew J. Lindsay, Stéphanie Miserey-Lenkei, and Bruno Goud
Assaying the interaction of the Rab guanine nucleotide exchange protein Sec2 with the upstream Rab, a downstream effector, and a phosphoinositide / Danièle Stalder and Peter J. Novick
Kinetic activation of Rab8 guanine nucleotide exchange factor Rabin8 by Rab11 / Shanshan Feng ... [et al.]
Ypt1 and TRAPP interactions : optimization of multicolor bimolecular fluorescence complementation in yeast / Zhanna Lipatova, Jane J. Kim, and Nava Segev
Identifying a Rab effector on the macroautophagy pathway / Juan Wang ... [et al.]
Functional analysis of Rab27A and its effector Slp2-a in renal epithelial cells / Takao Yasuda, Paulina S. Mrozowska, and Mitsunori Fukuda
Small GTPases in acrosomal exocytosis / Matias A. Bustos ... [et al.]
Rab antibody characterization : comparison of Rab14 antibodies / Andrew J. Lindsay and Mary W. McCaffrey
Selective visualization of GLUT4 storage vesicles and associated Rab proteins using IRAP-pHluorin / Yu Chen and Jennifer Lippincott-Schwartz
3D time-lapse analysis of Rab11/FIP5 complex : spatiotemporal dynamics during apical lumen formation / Anthony Mangan and Rytis Prekeris
In vitro and in vivo characterization of the Rab11-GAP activity of drosophila Evi5 / Carl Laflamme and Gregory Emery
Characterization of the role Rab25 in energy metabolism and cancer using extracellular flux analysis and material balance / Shreya Mitra ... [et al.]
Measurement of Rab35 activity with the GTP-Rab35 trapper RBD35 / Hotaka Kobayashi ... [et al.]
Analysis of connecdenn 1-3 (DENN1A-C) GEF activity for Rab35 / Patrick D. Allaire, Peter S. McPherson, and Brigitte Ritter
Assay of Rab17 and its guanine nucleotide exchange factor Rabex-5 in the dendrites of hippocampal neurons / Yasunori Mori and Mitsunori Fukuda
Methods for analysis of AP-3/Rabin4' in regulation of lysosome distribution / Viorica Ivan and Peter van der Sluijs
Determination of Rab5 activity in the cell by effector pull-down assay / Yaoyao Qi ... [et al.]
Identification of the Rab5 binding site in p110[beta] : assays for PI3K[beta] binding to Rab5 / Rachel S. Salamon ... [et al.]
Role of the Rab5 guanine nucleotide exchange factor, Rme-6, in the regulation of clathrin-coated vesicle uncoating / Elizabeth Smythe
Differential effects of overexpression of Rab5 and Rab22 on autophagy in PC12 cells with or without NGF / M. Caleb Marlin and Guangpu Li
Determining the role of Rab7 in constitutive and ligand- mediated epidermal growth factor receptor endocytic trafficking using single cell assays / Brian P. Ceresa
Visualizing directional Rab7 and TrkA cotrafficking in axons by pTIRF microscopy / Kai Zhang, Praveen D. Chowdary, and Bianxiao Cui
Quantitative bead-based flow cytometry for assaying Rab7 GTPase interaction with the Rab-interacting lysosomal protein (RILP) effector protein / Jacob O. Agola ... [et al.].

Summary: This book reviews the recent advances in rabies research and rabies vaccine development. The reader is introduced to biology and pathology of the virus, causing agents and the history of rabies vaccination. The book presents regional rabies prophylaxis programs and discusses vaccination strategies for wildlife and humans. Further, innate immune response as well as antibody response to rabies are examined. All chapters are written by renowned experts in rabies research, some of them part of the WHO Collaboration Centre for Rabies Surveillance and Research. The book targets researchers and health professionals working in Virology, Veterinary Medicine and Biomedicine.

Contents:
Rabies Life Cycle, Transmission and Pathogenesis
History of Rabies and Rabies Vaccines
Rabies vaccines for wildlife
Human Rabies Vaccines
Rabies vaccines, prophylactic, Peru
Rabies Prevention in Asia: Institutionalizing Implementation Capacities
Passive Immunity in Rabies Prophylaxis
Rabies Little Virus Against Powerful Innate Immunity
Novel Rabies Vaccines
Assessing the potency of inactivated veterinary vaccines and oral live vaccines against rabies
WHO Perspective on Rabies.

Summary: Rabies is the deadliest zoonotic disease that threatens humans and animals on all continents except Antarctica. Asia and Africa are worst affected as more than 95 per cent of rabies associated human deaths occur in these regions. India alone bears about 36 per cent of the global human rabies burden. Dogs are the main transmitters of rabies that potentially threaten over 3 billion people in Asia and Africa. Many developed nations have been able to successfully control dog rabies but continue to face the risk from wildlife including bats.

Contents:
Causation of Disease
Epidemiology
Rabies Manifestations and Diagnosis
Risk Assessment and Management of Exposures
Vaccines and Other Biologicals
Rabies Prevention and Control
Frequently Asked Questions.

Summary: Race, Work, and Leadership is a rare and important compilation of essays that examines how race matters in people's experience of work and leadership. What does it mean to be black in corporate America today? How are racial dynamics in organizations changing in a post-Obama era? How do we build inclusive organizations? Inspired by and developed in conjunction with the research and programming for Harvard Business School's 2018 celebration of the 50th anniversary of the founding of the HBS African American Student Union, this groundbreaking book shines new light on these and other timely questions and illuminates the present-day dynamics of race in the workplace. Contributions from top scholars, researchers, and practitioners in leadership, organizational behavior, psychology, sociology, and education test the relevance of long-held assumptions and reconsider the research approaches and interventions needed to understand and advance African Americans in work settings and leadership roles. At a time when there are fewer African American men and women in corporate leadership roles (following a peak in 2002), Race, Work, and Leadership will stimulate new scholarship and dialogue on the organizational and leadership challenges of African Americans and become the indispensable reference for anyone committed to understanding, studying, and acting on the challenges facing leaders who are building inclusive organizations.-- Provided by publisher.

Contents:
Foreword: Race in organizations: often cloaked but always present / by Ella L. J. Edmondson Bell and Stella M. Nkomo
Why a volume on race, work, and leadership? / by Laura Morgan Roberts, Anthony J. Mayo, and Serenity Lee
Section I. History and critical questions in black business leadership: A case study of leading change: the founders of Harvard Business School's African American student union / by Henry Louis Gates, Jr
Pathways to leadership: black graduates of Harvard Business School / by Anthony J. Mayo and Laura Morgan Roberts
Commentaries: The struggle is real: black colleges, resources, and respect / by Melissa E. Wooten
Back to the future: a strategy for studying racism in organizations / by Arthur P. Brief
Intersectionality and the careers of black women lawyers: results from the Harvard Law School Black Alumni Survey / by David B. Wilkins and Bryon Fong
Section II. Comparative studies: Workplace engagement and the glass ceiling: the experience of black professionals / by Ella Washington, Ellyn Bass, & Shane McFeely
Authenticity in the workplace: an African American perspective / by Patricia Faison Hewlin & Anna-Maria Broomes
Feeling connected: the importance of engagement, authenticity, and relationships in the careers of diverse professionals / by Stacy Blake-Beard, Laura Morgan Roberts, Beverly Edgehill, & Ella Washington
Section III. Phenomenological studies: the lived experience: Views from the other side: black professionals perceptions of diversity management / by Adia Harvey Wingfield
Overcoming barriers to developing and retaining diverse talent in healthcare professions / by Laura Morgan Roberts, Stacy Blake-Beard, Stephanie Creary, Beverly Edgehill and Sakshi Ghai
From c-suite to start-ups: an illusion of inclusion / by Toigo Foundation (Nancy Sims, Sue Toigo, Maura Allen & Toni Cornelius)
Rough waters of resistance: black instructional coaches impacted by implicit bias / by Michelle Smith Macchia & Kisha Porcher
A million gray areas: how two friends crossed paths professionally and personally and mutually enhanced their understanding of relationships of race, gender, class and power / by Kathryn Fraser and Karen Samuels
African American women as change agents in the white academy: pivoting the margin via grounded theory / by Muriel E. Shockley and Elizabeth L. Holloway
The transformational impact of black women/womanist theologians leading intergroup dialogue in liberation work of the oppressed and the oppressor / by Tawana Davis
Psychodynamics of black authority
sentience and sellouts: ol' skool civil rights and woke Black Lives Matter / by Diane Forbes Berthoud, Flora Taylor, and Zachary Green
Section IV. Theorizing black leadership: Is D&I about us?: how inclusion practices undermine black advancement and how to design for real inclusion / by Valerie Purdie-Greenaway & Martin N. Davidson
The glass cliff: African American CEOs as crisis leaders / by Lynn Perry Wooten & Erika Hayes James
When black leaders leave: costs and consequences / by Kecia Thomas, Aspen J. Robinson, Laura Provolt, and B. Lindsay Brown
Blacks leading whites: how mutual and dual (ingroup and outgroup) identification affect inequality / by Lumumba Seegars and Lakshmi Ramarajan
Managing diversity, managing blackness?: an intersectional critique of diversity management practices / by Courtney L. McCluney & Verónica Caridad Rabelo
Uncovering the hidden face of affinity fraud: race-based predatory bias, social identity and the need for inclusive leadership / by Audrey Murrell, Ray Jones, & Jennifer Petrie
Section V. The future: lessons for the next generation of leaders: Ujima: lifting as we climb to develop the next generation of African American leaders / by Lynn Wooten, Shannon Polk, and Whitney Williams
Conclusion: Intersection of race, work, and leadership: lessons in advancing black leaders / by Laura Morgan Roberts and Anthony J. Mayo.

Summary: This book discusses the poor and people of color and their struggle to take control of one of the most basic aspects of their lives: the quality of their environment. It exposes the fact of environmental inequity and its consequences in face of general neglect by policymakers and social scientists.

Contents:
Introduction / Bunyan Bryant and Paul Mohai
Toxic waste and race in the United States / Charles Lee
Can the environmental movement attract and maintain the support of minorities? / Dorceta Taylor
The environmental voting record of the congressional Black caucus / Henry Vance Davis
Toward a model of "environmental discrimination" / Michel Gelobter
Environmental blackmail in minority communities / Robert Bullard
Invitation to poison? Detroit minorities and toxic fish consumption from the Detroit river / Patrick C. West
Minority anglers and toxic fish consumption : evidence from a statewide survey of Michigan / Patrick C. West [and 3 others]
The effects of occupational injury, illness, and disease on the health status of Black Americans : a review / Beverly Hendrix Wright
Hazardous waste incineration and minority communities / Harvey L. White
Environmentalism and civil rights in Sumter County, Alabama / Conner Bailey and Charles E. Faupel
Uranium production and its effects on Navajo communities along the Rio Puerco in Western New Mexico / Wm. Paul Robinson
Environmental racism : reviewing the evidence / Paul Mohai and Bunyan Bryant
Pesticide exposure of farm workers and the International connection / Ivette Perfecto
The dumping of toxic waste in African countries : a case of poverty and racism / Mutombo Mpanya
Summary / Bunyan Bryant and Paul Mohai.

Summary: "A Race Is a Nice Thing to Have: A Guide to Being a White Person or Understanding the White Persons in Your Life is designed to help White people fully recognize and accept their racial identity, assume the proper responsibility for ending racism, and develop an understanding of how racism impacts their own racial group. This powerful text encourages positive racial adjustment and deeper levels of self-understanding. The book explores the meaning of race in society, the "color-blindness" movement, the problem of ignorance about Whiteness, the various phases of internalized racism, and other critical topics. Evocative and meaningful activities throughout the text foster reflection and increased levels of self-awareness and acceptance. The third edition features updated references and charts, as well as a new foreword by Dr. Allen Ivey"-- Publisher description.

Contents:
The meaning of race in society
Social class is not race
Who needs a color-blind society?
I'm not colored!
But what color am I?
Recognizing racism
A model of white racial identity development
Contact : "I'm an innocent"
Disintegration : "How can I be white?"
Reintegration : "We have the best because we are the best!"
Pseudo-independent : "Let's help them become more like whites"
Immersion/emersion : "I'm white!"
Autonomy : "I see color and like it!"
Using racial identity schemas to understand daily events
Epilogue.

Summary: "First published in 1993, on the one-year anniversary of the Los Angeles riots, Race Matters became a national best seller that has gone on to sell more than half a million copies. This classic treatise on race contains Dr. West's most incisive essays on the issues relevant to black Americans, including the crisis in leadership in the Black community, Black conservatism, Black-Jewish relations, myths about Black sexuality, and the legacy of Malcolm X. The insights Dr. West brings to these complex problems remain relevant, provocative, creative, and compassionate. In a new introduction for the twenty-fifth-anniversary edition, Dr. West argues that we are in the midst of a spiritual blackout characterized by imperial decline, racial animosity, and unchecked brutality and terror as seen in Baltimore, Ferguson, and Charlottesville. Calling for a moral and spiritual awakening, Dr. West finds hope in the collective and visionary resistance exemplified by the Movement for Black Lives, Standing Rock, and the Black freedom tradition. Now more than ever, Race Matters is an essential book for all Americans, helping us to build a genuine multiracial democracy in the new millennium."--Amazon.com.

Contents:
Preface 2001: Democracy matters in race matters
Preface 1993
Race matters in twenty-first century America
Introduction: Race matters
Nihilism in Black America
The pitfalls of racial reasoning
The crisis of Black leadership
Demystifying the new Black conservatism
Beyond Affirmative Action: equality and identity
On Black-Jewish relations
Black sexuality: the taboo subject
Malcolm X and Black rage
Epilogue.

Summary: This book covers the key basics of tissue engineering as well as the latest advances in the integration of both antimicrobial and osteoinductive properties. Topics covered include osteoconductive and osteoinductive biomaterials (calcium phosphate, bone morphogenetic protein, peptides, antibodies, bioactive glasses, nanomaterials, etc.) and scaffolds. Research integrating both antimicrobial/biofilm-inhibiting and osteoinductive/osteoconductive properties and their co-delivery is detailed and their roles in clinical success are discussed. Combined with its companion volume, Racing for the Surface: Antimicrobial and Interface Tissue Engineering, this book bridges the gap between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in tissue engineering and regeneration, infection, and biomaterials and devices.

Contents:
Part I: Innovative antimicrobial and osteoinductive therapeutics
Advances in antimicrobial and osteoinductive biomaterials
Recent Advances in Controlled Release Technologies for the Co-Delivery of Antimicrobial and Osteoconductive Therapeutics
Biofilm-inhibiting and osseointegration-promoting orthopedic implants with novel nanocoatings
Three dimensional (3D) and drug-eluting nanofiber coating for prosthetic implants
Cationic antimicrobial coatings with osteoinductive properties
Peptide Functionalized Biomaterials with Osteoinductive or Anti-biofilm Activity
Construction of bio-functionalized ZnO coatings on titanium implants with both self-antibacterial and osteoinductive properties
Gasotransmitters: antimicrobial properties and impact on cell growth for tissue engineering
Carbon nanotubes: Their antimicrobial properties and applications in bone tissue regeneration
Part II: Interface tissue engineering and advanced material for scaffolds
Fracture healing and progress towards successful repair
Animal models for bone tissue engineering and osteoinductive biomaterial research
Bioprinting in Tissue Engineering
Additive Manufacturing of Bio-scaffolds for Bone Regeneration
Anti-biofouling and Antimicrobial Biomaterials for Tissue Engineering
Osteoinductive and osteoconductive biomaterials
Bimetallic nanoparticles for biomedical applications: a review
Peptide-mediated Bone Tissue Regeneration
Antibody mediated osseous regeneration
a new strategy for bioengineering
Extracellular matrix-based materials for bone regeneration
Calcium Phosphate Biomaterials for Bone Tissue Engineering: Properties and Relevance in Bone Repair
Bioactive Glasses in Orthopedic Applications
Advances in Tissue Engineering and Regeneration
SCAFFOLDS FOR TISSUE ENGINEERING: A state of the art review concerning types, properties, materials, processing and characterization
Recent Developments of Zn-Based Medical Implants
Recent physical interaction-based bioadhesives
Tellurium, the forgotten element: a review for the properties, processes and biomedical applications of the bulk and nanoscale metalloid
Index.

Summary: This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.

Contents:
Insights into the emergence, clinical prevalence and significance of Staphylococcus aureus small colony variants
Periprosthetic Joint Infection
Complications in orthopedic trauma surgery: fracture related infection
Chiral Stereochemical Strategy for Antimicrobial Adhesion
Perspectives on and need to develop new infection control strategies
Battling bacteria with free and surface-immobilized polymeric nanostructures
Engineering Approaches to Create Antibacterial Surfaces on Biomedical Implants and Devices
3D Printed Ceramic-Polymer Composites for Treating Bone Infection
Bioinspired interfaces for the management of skin infections
Antimicrobial endodontic materials
Local Delivery of Anti-biofilm Therapeutics
Device-Related Infections
Advances in polysaccharide based antimicrobial delivery vehicles
Antibacterial Coatings on Medical Implants
Perspectives on biomaterial-associated infection: pathogenesis and current clinical demands
Polymeric Nanoparticulate Delivery Vehicles of Antimicrobials for Biofilm Eradication
Pathogenesis of biomaterial-associated infection
Metal- and Polymer-Based Nanoparticles for Advanced Therapeutic and Diagnostic System Applications
Antimicrobial Material in Arthroplasty
Antimicrobial Hydrogels: Key Considerations and Engineering Strategies for Biomedical Applications
Antibacterial Polymeric and Peptide Gels/Hydrogels to Prevent Biomaterial-related Infections
The Impact of Bacterial Biofilms in Transfusion Medicine
Mechanisms of Action and Chemical Origins of Biologically Active Antimicrobial Polymers
When the Race is Lost: The Clinical Impact of Prosthetic Joint Infections
Antibacterial Hydroxyapatite: An Effective Approach to Cure Infections in Orthopedics
Index.

Summary: "This book outlines the relationship between racism and health, while providing public health professionals with a variety of actions, strategies, and tools to understand and address the public health implications of racism, as well as inspiration to pursue health equity"-- Provided by publisher.

Contents:
1. Is racism a public health issue?
2. How does racism affect health?
3. What do we do?
4. Are there group-specific experiences?
5. Where do we go from here?

Summary: Eduardo Bonilla-Silva's acclaimed Racism without Racists is a provocative book that explodes the belief that America is now a color-blind society. The fifth edition includes a new chapter addressing what readers can do to confront racism, new material on the racial climate post-Obama, new coverage of the Black Lives Matter movement, and more.

Contents:
Preface to the fifth edition
The strange enigma of race in contemporary America
The new racism : the U.S. racial structure since the 1960s
The central frames of color-blind racism
The style of color blindness : how to talk nasty about minorities without sounding racist
"I didn't get that job because of a black man" : color-blind racism's racial stories
Peeking inside the (white) house of color blindness : the significance of whites' segregation
Are all whites refined Archie Bunkers? : an examination of white racial progressives
Are blacks color blind, too?
E pluribus unum, or the same old perfume in a new bottle? On the future of racial stratification in the United States
From Obamerica to Trumpamerica : the continuing significance of color-blind racism
Conclusion: What is to be done? Talking with your about how to fight color
Blind racism in America.

Summary: "RadCases Gastrointestinal Imaging Second Edition by Stephen Thomas and Jonathan M. Lorenz expands on the rich study experience that has been tried, tested, and popularized by radiology residents around the world. This new edition includes important variations on prior cases, updated diagnostic and management strategies, and new pathological entities. One hundred new, carefully selected GI cases are focused on helping radiology residents navigate and assimilate a daunting volume of digestive-related information. For maximum ease of self-assessment, each case begins with the clinical presentation on the right-hand page; study that and then turn the page for imaging findings, differential diagnoses with the definitive diagnosis, essential facts, pearls and pitfalls, and more"-- Provided by publisher.

Summary: "This volume on Head and Neck Imaging will complete the corpus of content for the RadCases series. As with all RadCases volumes, Head and Neck Imaging contains 100 cases in the print book and an additional 150 cases online. The content covers the imaging of the various structures of the head and neck, including the temporal bone, the skull base, all ear and orbit structures, all nanasal structures and paranasal sinuses, the neck and its structures and glands, the larynx, etc. Following the proven RadCases format, each case begins with the clinical presentation on the first page, and the second page provides image findings, differential diagnoses, definitive diagnoses, essential facts, Pearls and Pitfalls, all with high-quality images. RadCases simulates what the resident finds on rounds, rotations, and exams"--Provided by publisher.

Summary: "The second edition of the book Radiation Detection Systems presents variety of radiation detection systems giving readers a broad view of the state-of-the-art in the design of detectors, front-end electronics and systems offering optimized choices of the detection tools for a particular application. The new edition has been divided into two volumes. This first volume, on Sensor Materials, Systems, Technology and Characterization Measurements puts emphasis on sensor materials, detector structures, front electronics technology and their designs as well as system optimization for different applications. Also, the book include characterization measurements of the developed detection systems."-- Provided by publisher.

Summary: The role of disaster medicine is becoming more important as the frequency and severity of natural and technological disasters increase. The triple disaster that occurred in Fukushima on March 11, 2011 calls for innovation in the training of health care professionals, pre-hospital emergency care providers, and emergency personnel in the management of the medical consequences of radiation disasters. While many books are available on disaster medicine, none is specifically devoted to the role of physicians in the management of patients exposed to radiation leakage from a damaged nuclear power plant. Radiation Disaster Medicine aims to fill this void based on the response to the Fukushima nuclear accident. Each chapter addresses principles and practices of radiation medicine within the specific context of that accident. Topics covered include the role of physicians in radiation disasters, the concepts of external and internal exposure, prehospital and hospital response, disaster behavioral health, and radiation emergency response from the perspective of national and international institutions. Most of the contributors are active educators and researchers in radiation medicine with first-hand experience in dealing with prehospital triage and management of patients within secondary and tertiary care hospitals in Japan. It is hoped that this book will assist in attaining the ultimate goal of radiation disaster medicine: to help the patients.

Contents:
Physicians' early response to Fukushima Daiichi nuclear power plant accident: Challenges and lessons learned
General considerations in radiation disaster medicine
Medical perspective
Pre-hospital emergency medical response
Hospital emergency medical response
Disaster behavioral health: Psychological effects of the Fukushima nuclear power plant accident
Management perspective: Structure of radiation emergency response in Japan
Management perspective: Structure of radiation emergency response in International Organizations
Radiation disaster medicine curriculum revisited in a post-Fukushima context.

Summary: This book covers every aspect of radiation myelopathy and considers the evidence from all species in which it has been studied. The historical and current understanding of the pathogenesis of this rare but devastating injury is first discussed. The evidence regarding the role of a variety of factors in radiation myelopathy is then reviewed. Readers will find detailed information on the impacts of total radiation dose, radiation volume, dose fractionation, hyper fractionation, age, anatomic level, comorbidities, radiation modifiers, other therapies, and retreatment of the spinal cord. Given the similarity of the pathogenesis of radiation myelopathy in humans and experimental animals, the potential for cross-species modelling of dose response is explored, with attention to relevant species differences. Treatment of the condition is also fully considered. New theories are presented regarding retreatment, small volume response, and the final step in white matter necrosis. The final chapter addresses the medicolegal issues elicited by radiation myelopathy, which is often the result of treatment error. Radiation Myelopathy will be of high value for radiation oncologists, radiation physicists, dosimetrists, biologists, neurologists, medical oncologists, and attorneys.

Contents:
History
Pathogenesis of radiation myelopathy
Clinical radiation myelopathy
Radiation myelopathy in stereotactic radiosurgery
Experimental studies on fractionation effects
Experimental studies on volume effects
Other clinical and experimental studies
Multispecies dose response model
Treatment of myelopathy
Medico-legal issues.

Summary: This book is an evidence-based guide to current use of radiation therapy for the treatment of malignancies at major disease sites. It is designed to meet the needs of residents, fellows, and practicing radiation oncologists and will assist in selection and delineation of tumor volumes/fields and dose prescription for intensity-modulated radiation therapy, including volumetric modulated arc therapy for stereotactic radiosurgery or stereotactic body radiotherapy. Each tumor site-related chapter presents, from the perspective of an academic expert, informative cases at different stages in order to clarify specific clinical concepts. The coverage includes case presentation, a case-related literature review, patient preparation, simulation, contouring, treatment planning, image-guided treatment delivery, follow-up, and toxicity management. The text is accompanied by illustrations ranging from slice-by-slice delineations on planning CT images to finalized plan evaluations based on detailed acceptance criteria. The expert knowledge and evidence contained in this comprehensive book will give readers the confidence to manage common cancers without outside referral and to meet the clinical challenges faced in everyday practice.

Contents:
Centrtal nervous system tumors
Head and neck cancers
Lung cancer
Breast cancer
Gastrointestinal system cancers
Genitourinary system cancers
Gynecological cancers
Sarcoma
Lymphoma.

Contents:
Pediatrics
Central nervous system
Eye
Head and neck
Thorax
Breast
Gastrointestinal
Genitourinary
Gynecology
Hematology
Bone
Soft tissue sarcoma
Skin
Palliative
Benign disease

Summary: Known among radiation oncology residents as "the green book," Radiation Oncology: A Question-Based Review is a must-have learning tool for trainees and physicians who want to strengthen their long-term command of radiation oncology. The updated 3rd Edition reflects state-of-the-art advances in the field, with revised questions and answers, new professional guidelines, and new annual content updates for the eBook. Offers detailed questions on the natural history, epidemiology, diagnosis, staging, treatment recommendations, and treatment-related side effects for each cancer type. Contains a new primer section on immunotherapy. Retains popular features such as memory aids, quick-reference tables, and useful facts from other relevant disciplines such as radiology, anatomy, and medical oncology. Incorporates the latest ASTRO, AJCC, and NCCN guidelines, as well as seminal new studies and practice-changing trials, to reflect current radiation oncology practice. Includes new annual updates to the eBook for the life of the edition, with revised questions or answers that keep you current with new knowledge in the field. Ideal for both trainees and radiation oncologists as a high-yield introduction and review of the clinical management of major cancer types and conditions that are currently treated with radiation. Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities! Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more."--Provided by publisher.

Contents:
Part I: Pediatrics
Part II: Central nervous system
Part III: Eye
Part IV: Head and neck
Part V:
Thorax
Part VI: Breast
Part VII: Gastrointestinal
Part VIII: Genitourinary
Part IX: Gynecology
Part X: Hematology
Part XI: Bone
Part XII: Soft tissue
Part XIII: Skin
Part XIV: Palliative
Part XV: Benign disease
Part XVI: Immunotherapy primer

Summary: "Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Updated with details on the newest therapies and sporting a new full-color design, this latest edition of Radiation Oncology: Management Decisions continues to offer comprehensive guidance for residents as well as radiation oncologists already in professional practice. You'll discover the latest treatment plans for numerous cancer sites and tumor types, including the mouth and sinus, gastrointestinal areas, lungs, bones, and blood. Concise, easy-to-read material you can use in a clinical setting immediately with patients! Combines comprehensive overviews of basic concepts with the latest radiologic treatment regimens for a wide variety of tumor types and cancer sites. Now in full color! Bursting with hundreds of illustrations, figures, and images to illuminate visually important and state-of-the-art techniques. Heavily bulleted content format and to-the-point writing style makes content easy to digest and use with patients quickly. Chapters that address tumor- or site-specific treatments cover screening, assessment, staging, therapeutic developments, and other key information. Features an up-to-date list of commonly prescribed drugs--streamlined for easier reading--and coverage of the latest pain management and palliative treatments. Enrich Your eBook Reading Experience with Enhanced Video, Audio and Interactive Capabilities! Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. Adapt for unique reading needs, supporting learning disabilities, visual/auditory impairments, second-language or literacy challenges, and more."--Provided by publisher.

Contents:
Epidemiology of childhood brain tumors / Philip J. Lupo, Surya P. Rednam, and Murali Chintagumpala
Histopathology of primary tumors of the central nervous system / Adekunle M. Adesina
Imaging of pediatric central nervous system tumors / Edgar G. Ordonez-Rubiano, Rachel S. Hicklen, Laura Rivera-Osorio and Jason M. Johnson
Surgical principles in the treatment of pediatric brain tumors / Eric N. Momin, Mahmood Khan, and Andrew Jea
Chemotherapeutic strategies in brain tumors / Soumen Khatua
Medulloblastoma / Arnold C. Paulino and Christian Carrie
Supratentorial primitive neuroectodermal tumor / Mary Frances McAleer
Atypical teratoid rhabdoid tumors (AT/RT) and ETMR / Susan L. McGovern
Ependymoma / Rosangela Correa Villar and Thomas E. Merchant
Low-grade glioma / Rolf-Dieter Kortmann and Arnold C. Paulino
Optic pathway glioma / Julie A. Bradley, Ronny L. Rotondo, and Daniel J. Indelicato
High-grade glioma / Scheryll Alken, Fernando Carceller, Henry Mandeville, and Frank Saran
Brainstem tumors / Carolyn R. Freeman, Jean-Pierre Farmer, and Nada Jabado
Central nervous system germinoma / Yuta Shibamoto and Shinya Takemoto
Central nervous system nongerminomatous germ cell tumors / Ji Hoon Phi, Chuhl Joo Lyu, and Joo-Young Kim
Craniopharyngioma / Andrew J. Bishop and David R. Grosshans
CNS leukemia / Yi An and Kenneth B. Roberts
Spinal tumors / Natia Esiashvili, Ronica Nanda, Mohammad Khan, and Bree Eaton
Choroid plexus tumors / Arthur K. Liu, Todd Hankinson, and Johannes E. A. Wolff
Proton therapy for skull base chordomas in the pediatric and adolescent patient / Eugen B. Hug
Pituitary tumors : pituitary adenomas and langerhans cell histiocytosis associated diabetes insipidus / Ralph P. Ermoian
Pediatric brain metastases / Radhika Sreeraman Kumar and Ronny L. Rotondo
Anesthesia for immobilization / Pascal Owusu-Agyemang
Image guidance in pediatric brain radiotherapy / Sara Alcorn and Stephanie Terezakis
Conformal radiation therapy for pediatric CNS tumors / Thomas B. Daniels and Nadia N. Laack
Proton therapy for pediatric brain tumors / Anita Mahajan
Craniospinal irradiation / Bree R. Eaton, Judith Adams, and Torunn I. Yock
Special radiation techniques for pediatric brain tumors / Susan M. Hiniker and Iris C. Gibbs
Reirradiation / Patricia E. Daly and Normand J. Laperriere
Neuropsychological late effects of radiotherapy for pediatric brain tumors / Marsha Nortz Gragert, Tanya N. Antonini, and Lisa S. Kahalley
Endocrine sequelae of central nervous system irradiation / Steven G. Waguespack and Wassim Chemaitilly
Ophthalmic outcomes for children treated with CNS radiation / Irene T. Tung and Jane C. Edmond
Hearing / Paul W. Gidley
Vascular late effects of cranial radiation / Christine Hill-Kayser and Louis Constine
Second neoplasms after successful treatment for pediatric central nervous system tumors / Mark J. Amsbaugh and Shiao Y. Woo
Afterword / Edward C. Halperin.

Summary: Now in its second edition, this popular text remains a comprehensive study and review aid for the radiation oncology trainee and practicing radiation oncologist. The updated Radiation Oncology Study Guide, 2e maintains its robust Q&A format, and has been comprehensively updated to include the latest staging information and treatment methods. Answer rationales have been modified to a more readable, high yield bulleted format. Each chapter covers a major disease site and is divided into two main parts: Questions & Answers and Rationale. Questions review the scope of clinical practice, spanning from initial presentation to complications of treatment. General content and work-up questions emphasize "pearls" of epidemiology, anatomy, pathology, clinical presentation, and staging. Treatment content questions not only review evidence-based data guiding treatment recommendations, but also practical aspects of radiation treatment planning, pertinent radiobiology and physics, and complications of treatment. This book is an ideal resource for physicians-in-training to prepare for initial written and oral exams and physicians in practice to maintain their skills and prepare for maintenance of certification longitudinal and written exams.

Contents:
Central Nervous System Tumors
Skin Cancer
Head and Neck Cancer
Lung Cancer
Tumors of the Mediastinum
Breast Cancer
Upper Gastrointestinal Cancers
Lower Gastrointestinal Cancers
Cancers of the Urinary System
Male Genitourinary Cancers
Gynecological Cancers
Lymphomas
Leukemia
Soft Tissue Sarcomas and Bone Tumors
Pediatric Non-CNS Tumors
Clinical Physics and Radiobiology
Palliation.

Summary: The book covers all the radiation safety aspects while working with unsealed radionuclides. Radiation safety plays a significant role in routine nuclear medicine practices and is necessary to protect occupational workers, patients, members of the general public and the environment. A fair knowledge of radiation safety is expected from all nuclear medicine professionals. Chapters include basics of radiation physics, biological bases of radiation protection, planning and design of nuclear medicine facilities, cyclotron and high dose therapy facilities, radiation safety considerations in nuclear medicine, cyclotron while preparing radiopharmaceuticals. It also includes the working mechanism of radiation detectors, quality assurance of positron emission tomography (PET) and gamma camera, including single photon emission computed tomography (SPECT), emergency preparedness plan, nuclear medicine and CT dosimetry, transport regulations, the role of national regulatory authorities and radioactive waste management. The last chapter provides probable model questions asked in the radiological safety officer certification examination and includes 250 multiple-choice questions (MCQs), 100 true or false, 60 fill in the blanks, and 40 match the following questions. The book is written in a simple language for a better understanding of the occupational workers of any grade. It serves as reference material for nuclear medicine professionals on radiation safety, related to planning, quality assurance, dosimetry and various regulations pertaining to nuclear medicine. It is a ready reckoner for the students pursuing a degree/diploma in nuclear medicine and preparing for certification courses in radiation safety to understand the subject matter along with options to attempt practice questions.

Contents:
Basics of Radiation Physics
Radiation Quantities and Units
Interaction of Radiation with Matter
Working mechanism of Radiation Detectors used in NM
Radiation Protection Standards in relation to ICRP recommendations
Radiation Hazards Evaluation and Control
Occupational and Public Exposure in Nuclear Medicine
Biological Bases of Radiation Protection
Planning of Nuclear Medicine facilities & including Shielding Calculations
Planning & Design of High Dose Therapy Facility
Planning & Design of Medical Cyclotron Facility
Radiation Safety consideration during Radiopharmaceutical preparation
NEMA and Routine Quality Control of SPECT & SPECT-CT
NEMA and Routine Quality control of PET-CT
Personnel Monitoring & Radiation Protection Survey in Nuclear Medicine
Radiological Safety Consideration in Nuclear Medicine
Radiation Emergencies and its Preparedness
Radioactive Waste Disposal including disused radioactive sources
Internal Dosimetry
CT Dosimetry
Transport of Radioactive Material
Legislation and Role of National Regulatory Authority in Nuclear Medicine
International Scenario in Nuclear Medicine Regulations
MCQs in in Nuclear Medicine.

Summary: This book is a collection of all pertinent information on radiation safety applicable in nuclear medicine and research using radioactive materials. Radiation exposure causes harm to humans and is strictly controlled by several regulatory authorities (NRC, FDA, EPA, DOT, etc). The practice of nuclear medicine involves the use of radioactive materials in patients and research, and is well regulated by these agencies. However, information on radiation safety practice in nuclear medicine and research areas is scattered throughout the literature and federal registers. For busy nuclear technologists and professionals, it is quite time consuming to look for and acquire specific information and instructions to follow in radiation-related occasions and incidents. This guide provides ready-made, handy information on radiation safety as required in the practice of nuclear medicine, presented in a concise form for easy understanding and quick reference related to a given situation and/or incident. This is an ideal reference for nuclear medicine physicians, nuclear medicine technologists, and researchers using radioactive materials.

Contents:
Basic Physics in Radiation Safety
Essential Equipment in Radiation Safety
Radiation Units and Absorbed Dose
Radiation Protection
Radiation Exposure
Regulatory Framework for Radiation Protection
Medical Uses of Radioactive Materials
Training and Experience of Personnel
Emergency Procedures
Radioactive Waste Disposal
Biological Effects of Radiation
Transportation of Radioactive Material.

Contents:
1 Primary Central Nervous System Lymphomas
2 Ocular Adnexal Lymphoma
3 Extranodal NK/T Cell lymphoma, Nasal Type
4 Thyroid Lymphoma
5 Pyothorax-associated lymphoma (PAL)
6 Stomach
7 Intestinal lymphomas
8 Primary Testicular Lymphoma
9 Cutaneous Lymphomas.

Contents:
Basics of Chemotherapy
Esophageal Cancer: Clinical Data
Esophageal Cancer: Contouring and treatment planning
Gastric Cancer: Clinical Data
Gastric Cancer: Contouring and treatment planning
Pancreatic Cancer: Clinical Data
Pancreatic Cancer: Contouring and treatment planning
Primary Liver Cancer (hepatocellular carcinoma and Intrahepatic Cholangiocarcinoma): Clinical Data
Primary Liver Cancer (hepatocellular carcinoma and Intrahepatic Cholangiocarcinoma): Contouring and treatment planning
Biliary Cancer (Extrahepatic Bile Duct and Gallbladder): Clinical Data
Biliary Cancer (Extrahepatic Bile Duct and Gallbladder): Contouring and treatment planning
Colon Cancer: Clinical Data
Colon Cancer: Contouring and treatment planning
Rectal Cancer: Clinical Data
Rectal Cancer: Contouring and treatment planning
Anal Cancer: Clinical Data
Anal Cancer: Contouring and treatment planning
Pelvic Recurrences: Clinical Data
Pelvic Recurrences: Contouring, treatment planning, and Intra-operative Radiation Therapy
Stereotactic Body Radiation Therapy to the Liver for Metastatic disease: Clinical Data
Stereotactic Body Radiation Therapy to the Liver for Metastatic disease: Contouring and treatment planning.

Summary: This book is a comprehensive guide to the use of modern radiation therapy techniques for prostate cancer and other common and rare genitourinary malignancies. It will be an ideal resource for clinicians and trainees wishing to delve more deeply into the practical and technical aspects of radiotherapy for these malignancies and will serve to enhance day-to-day management in clinical practice. The first section is devoted to prostate cancer and includes coverage of low dose rate and high dose rate brachytherapy, conventionally fractionated, moderately hypofractionated, and ultra-hypofractionated external beam radiotherapy, and proton therapy. The second section focuses on radiotherapy considerations in relation to bladder cancer, testicular cancer, renal cell carcinoma, and rare malignancies such as penile cancer and urethral cancer. Radiotherapeutic treatment of patients with genitourinary malignancies now involves unprecedented precision and complexity, and this book will enable readers to exploit fully the exciting advances that have been achieved in recent years.

Contents:
Section 1: Prostate Cancer
1. The Management of Prostate Cancer
2. Imaging in Prostate Cancer
3. Androgen Deprivation Therapy
4. Conventional and Moderately Hypofractionated External Beam Radiotherapy
5. Low Dose Rate Prostate Brachytherapy
6. High Dose Rate Prostate Brachytherapy
7. Ultra-hypofractionated Radiotherapy (Stereotactic Body Radiotherapy)
8. Proton Therapy
9. Post-prostatectomy Radiotherapy
10. Role of RT in the setting of Metastatic Disease
Section 2: Non-prostate Genitourinary Malignancies
11. Bladder Cancer Radiotherapy
12. Testicular Cancer Radiotherapy
13. Renal Cell Carcinoma Radiotherapy
14. Radiotherapy for Rare GU malignancies (including Penile, Urethral, ureteral/renal pelvis).

Contents:
Part I: Fundamentals
Liver Anatomy and Function
Imaging Characteristics of Normal liver and liver tumors
Assessment of Liver Function: Focus on the ALBI Score
Radiation Oncology: Fundamentals and Controversies
Radiation Sensitivity of the Liver: Models and Clinical Data
Part II: Principles of Surgery, Intra-arterial Therapies, and Thermal Ablation
Surgical Considerations
Principles of Intra-arterial Therapies
Principles of Thermal Ablation
Part III: Principles of Radiation Therapy
External beam radiation therapy for liver tumors: Simulation, Treatment Planning, and Advanced Delivery Techniques
Particle Radiation Therapy for Liver Tumors: Simulation and Treatment Planning
Yttrium-90 Selective Internal Radiation Therapy
Interstitial Brachytherapy For Liver Tumors: Practical Issues
Part IV: Hepatocellular Carcinoma
Hepatocellular Carcinoma: Epidemiology, Basic Principles of Treatment, and Clinical Data
Radiation Therapy for Hepatocellular Carcinoma: Clinical Data
Part V: Intrahepatic and Hilar Cholangiocarcinoma
Intrahepatic and Hilar Cholangiocarcinoma: Epidemiology, Basic Principles of Treatment, and Clinical Data
Radiation Therapy for Intrahepatic and Hilar Cholangiocarcinoma: Clinical Data
Part VI: Liver Metastases
Liver Metastases: Basic Principles of Treatment and Clinical Data
Radiation Therapy for Liver Metastases: Clinical Data
Part VII: Perspectives on Multidisciplinary Management
Multidisciplinary Model for Liver Tumors
Part VIII: Future Directions
Radiation Therapy for Liver Tumors: Future Directions.

Summary: This book provides a state-of-the-art review of the role of radiation therapy in various pelvic malignancies as well as the consequences of the radiation in the pelvic tissues. With sections covering the role of radiation therapy in the various pelvic malignancies, the pathophysiology of radiation related injury and the risk factors that increase the possibility of such an injury, and the latest in medical, endoscopic and surgical therapies for these radiation related complications the text offers a concise yet comprehensive overview of radiation therapy in the human pelvis, its role and the adverse effects on the pelvic organs. Written by experts in the field with readers in mind, Radiation Therapy for Pelvic Malignancy and its Consequences is the first of its kind standalone reference on the subject. ℗ℓ Radiation Therapy for Pelvic Malignancy and its Consequences is of great value to urologists, medical radiation and gynecological oncologists, and gastroenterologists.

Contents:
The Role of Radiation Therapy in the Treatment of Malignant Gynaecological Tumors
Role of radiation in urological malignancies
Role of radiation in rectal cancers
Prevention of injury from pelvic irradiation
Pathology of Radiation Effects on Healthy Tissues in the Pelvis
Contribution of chemotherapy to the toxicity of pelvic irradiation
Radiation cystitis: Acute and Chronic
Acute and chronic radiation enteropathy
Radiation proctopathy
Effects of Radiation Therapy for Rectal Cancer on Anorectal Function
Effects and management of pelvic radiation on female reproductive system: Sexual dysfunction, fertility effects, and premature menopause
Miscellaneous pelvic effects: Pelvic/sacral insufficiency fractures
Radiation Induced Lumbosacral Plexopathy
The management of radiation cystitis
Medical management of Radiation Effects on the Intestines
Surgical management of radiation-induced intestinal injury. .

Summary: This practical guide to the use of radiotherapy for the treatment of sarcomas and skin cancers covers a wide range of disease scenarios, identifying which treatment techniques are applicable in particular clinical circumstances. Among the conditions considered are extremity soft tissue sarcomas, retroperitoneal soft tissue sarcomas, bone sarcomas, uterine sarcomas, chordomas, pediatric sarcomas, squamous cell carcinomas, basal cell carcinomas, melanomas, Merkel cell carcinomas, and cutaneous lymphomas. Detailed attention is devoted to the issues and considerations of relevance in everyday practice when treating these diseases. The use of multiple radiotherapy techniques and procedures, including IMRT, brachytherapy, radiosurgery, and particle therapy, is fully explained, and the role of radiotherapy in combination with chemotherapy and emerging therapeutics such as immunotherapy and biologic anticancer agents is also addressed. The book will be of high value for practicing radiation oncologists, medical and surgical oncologists, medical physicists, medical dosimetrists, trainees, and other medical professionals.

Contents:
PART I Sarcomas: Extremity soft tissue sarcoma
Retroperitoneal soft tissue sarcoma
Gynecologic sarcomas
Bone sarcomas
Chordomas
Oligometastatic sarcomas
Pediatric sarcomas
Particle therapy for sarcomas
Chemotherapy / radiosensitizers
PART II Other soft tissue tumors: Desmoid fibromatosis
Hemangiopericytomas / solitary fibrous tumors
Angiosarcomas
Dermatofibrosarcoma protuberans
PART III Skin cancers: Squamous cell carcinomas
Basal cell carcinomas
Melanomas
Merkel cell carcinomas
Cutaneous lymphomas.

Contents:
Hodgkin Lymphoma / Stephanie Terezakis, John P. Plastaras, pages 1-28
Diffuse Large B-Cell Lymphoma / N. George Mikhaeel, Lena Specht, pages 29-43
Follicular Lymphoma: Treatment for Early-Stage, Grades 1 and 2, and Advanced-Stage Disease / Bradford Hoppe, pages 45-53
Extranodal Marginal Zone Lymphoma / Umberto Ricardi, Andrea Riccardo Filippi, Cristina Piva, Mario Levis, pages 55-71-- Primary Mediastinal (Thymic) Large B-Cell Lymphoma / Andrea K. Ng, pages 73-83
Plasmacytoma and Multiple Myeloma / Richard Tsang, pages 85-96
Role of Radiation in the Treatment of Leukemias: Lymphoblastic Lymphoma, Central Nervous System Disease, and Chloromas / Bouthaina Shbib Dabaja, pages 97-114
Primary CNS Lymphoma / Chelsea Pinnix, pages 115-127
Primary Testicular Lymphoma / Andrew Wirth, Chan Yoon Cheah, pages 129-141
Radiation Therapy in the Management of Mantle Cell Lymphoma / Sarah A. Milgrom, pages 143-155
Extranodal NK/T-Cell Lymphoma, Nasal Type / Yexiong Li, pages 157-180
Radiation Therapy in the Management of Cutaneous T-Cell Lymphomas / Grace L. Smith, pages 181-197.

Summary: This book is a comprehensive review and study aid for radiation therapists. Organized in a question-and-answer format, it present clinical features and principles of treatment. Topics include radiation therapy physics, radiobiology, treatment and simulation equipment, principles of patient care, clinical components of cancer care, and cancers of the brain, head and neck region, and respiratory, digestive, urinary, and male and female reproductive systems. It offers over 500 multiple-choice questions with detailed answers and rationales. Radiation Therapy Study Guide is a valuable resource for radiation therapists preparing for certification examinations as well as for practicing therapists in need of a review.

Contents:
Radiation Physics
Radiation Protection and Safety
Radiobiology
Treatment and Simulation Equipment
Quality Assurance
Simulation and Treatment Planning
Treatment Delivery
Principles of Patient Care.- Professional Issues
Review of Pathophysiology
Clinical Components of Cancer Care
Cancers of the Brain and Central Nervous System
Cancers of the Head and Neck Region.- Cancers of the Respiratory System
Cancers of the Digestive System
Cancers of the Urinary System
Cancers of the Male Reproductive System
Cancers of the Female Reproductive System.- Oncology Review. .

Contents:
Whole Breast Radiation
Post-Mastectomy Radiation
Techniques for Internal Mammary Node Radiation
Target Delineation and Contouring
Accelerated Partial Breast Irradiation
Deep Inspiration Breath Hold
Intensity-Modulated Radiation Therapy
Techniques for Proton Radiation
Hyperthermia in Locally Recurrent Disease.

Summary: This book is a practical guide to the use of modern radiation therapy techniques in women with gynecological cancers. Step-by-step instruction is provided on simulation, contouring, and treatment planning and delivery for cancers of the cervix, endometrium, vagina, and vulva. Beyond external beam radiation delivery, full details are presented on three-dimensional brachytherapy at all sites for which it is applicable. Moreover, in-depth guidance is offered on the various advanced techniques of radiation delivery, including intensity-modulated radiation therapy, image guidance for external beam and brachytherapy, and stereotactic body radiotherapy. Radiation therapy is a critical component of the multidisciplinary management of gynecological tumors. With modern technology, both external beam radiation and brachytherapy can be delivered in a highly conformal way. This requires precise contouring and accurate planning techniques. In clearly describing the indications for and the delivery of quality radiation therapy for gynecological tumors, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and radiotherapy residents.

Contents:
CT and MRI Simulation for Radiation Planning
Anatomy and Target delineation - definitive and postoperative adjuvant radiation therapy for cervix cancer
Anatomy and Target delineation - definitive and postoperative adjuvant radiation therapy for uterine cancer
Anatomy and Target delineation - definitive and postoperative adjuvant radiation therapy for vulvar cancer
Three-Dimensional Planning Techniques- Pelvic and extended field
Intensity-Modulated Radiation Therapy and Volumetric Modulated Arc Therapy
Pelvic and extended field
Imaging in the Management of Gynecologic Cancers
Radiation Therapy Techniques for Gynecological Cancers: A comprehensive approach
Interstitial brachytherapy-Definitive and adjuvant
SBRT and other newer miscellaneous treatment delivery techniques.

Summary: In this book, leading experts in the dermatological and oncological field describe the use of radiation therapy for the treatment of the full range of dermatological malignancies ? including basal cell carcinoma, squamous cell carcinoma, cutaneous lymphomas, Kaposi's sarcoma, melanoma, and Merkel cell tumor ? as well as those precancerous lesions and non-malignant dermatological disorders which are amenable to radiation therapy. In each case the specific indications for the use of radiotherapy and its application are clearly explained with the aid of numerous high-quality illustrations. In addition, the book provides a concise introduction to physical and radiobiological principles, selection of radiation factors, dose definitions, radiation reactions, and risk assessments. The new edition has been thoroughly revised and updated to reflect advances in practical knowledge and clinical practice. It will be an invaluable source of information on the management of skin tumors and related non-malignant disorders for both dermatologists, oncologists and radiation oncologists.

Contents:
History of Dermatologic
Radiotherapy
Radiobiology of the Skin
Radiation Equipment
Radiation Treatment of Benign Dermatoses
Grenz Ray Treatment
Soft-X-Ray Treatment
Tumor Staging in Dermatology
Treatment of Precancerous Lesions
Radiation Treatment of Skin Carcinomas
Electron Therapy of Skin Carcinomas
Radiotherapy of Kaposi?s Sarcoma
Radiotherapy of Lymphomas
Indian Experience
Radiotherapy of Merkel Cell Carcinoma
Radiotherapy of Melanoma
Side Effects of Radiation Treatment
Radiation Accidents
Index. Index: The manuscript includes terms for the index. SPI should create an index and send proofs to the editors for approval.

Contents:
History of radical and reconstructive surgery for gynecologic cancer
Surgical anatomy and instrumentation
Radical hysterectomy with en bloc vaginectomy and pelvic lymphadenectomy
Fertility-sparing radical abdominal trachelectomy
Radical vulvectomy
Radical cystectomy
Abdominoperineal excision of the rectum
Pelvic exenteration
Laterally extended endopelvic resection
Bone and extended pelvic resections
Incontinent urinary diversions
Continent diversions
Bladder and ureteral substitution and augmentation
Colorectal anastomosis, colostomy, and small bowel anastomosis
The ileal pouch anal anastamosis
Skin grafts, omental flaps, advancement and rotational flaps
Rectus abdominis flaps and pudendal thigh and related flaps
Gracilis, tensor fascia lata, vastus laterlis, rectus femoris, and gluteus maximus flaps
Tissue rearrangement techniques and regional flaps
Bioprosthetic and prosthetic materials in abdominal wall reconstruction and hernia repair
Rehabilitation, quality of life, and symptom management.

Summary: Renowned political scientist Terri Givens calls for 'radical empathy' in bridging racial divides to understand the origins of our biases, including internalized oppression. Deftly weaving together her own experiences with the political, she offers practical steps to call out racism and bring about radical social change.

Contents:
Front cover
Halftitle Page
Title Page
Copyright Page
Dedication
Table of Contents
Note on the author
Prologue: Writing in a time of crisis
1. Bridging divides: From racism to empathy in the 21st century
2. Getting to radical empathy
3. My family's story: The isolation of internalized oppression
4. Racism and health disparities
5. Finding empathy in the academy
6. Love and marriage
7. Radical empathy in leadership: Creating change
8. Creating change at the national level: Restorative justice and working off the past
9. Revisiting the path to radical empathy
Epilogue: The long road ahead
Notes
Suggested reading
Index
Back cover

Summary: Radical Prostatectomy: Surgical Perspectives provides surgeons with a comprehensive overview of the anatomical approach to radical prostatectomy, whether done through an open (retropubic) or robotic-assisted laparoscopic approach. All chapters are structured to provide a step-by-step approach to the most technically demanding and most common oncologic procedure in urology surgery. The book includes highly practical presentations of typical surgical patients seen in the clinical practice of urology and relies heavily on illustrations and intraoperative photographs to clearly complement the text. In addition, the book ?includes a detailed description of the management of uncommon but potentially serious intraoperative complications, including major vascular injury, ureteral transaction, and rectotomy. Written by authors from a variety of integrated disciplines, including anesthesia, cardiology, and nursing Radical Prostatectomy: Surgical Perspectives is a unique and valuable resource in the field of urology both for those currently in training and for those already in surgical practices.

Contents:
Surgical Anatomy
Anesthetic Considerations: Open versus Minimally Invasive Surgery
Patient Positioning; Incision/Port Placement
Pelvic Lymph Node Dissection for Prostate Cancer
The Transperitoneal Robotic-Assisted Radical Prostatectomy
Robotic-Assisted Radical Prostatectomy: A Surgical Guide to the Extraperitoneal Approach
Open Radical Retropubic Prostatectomy
Salvage Robotic-Assisted Laparoscopic Radical Prostatectomy
Open Salvage Radical Prostatectomy for Recurrence of Prostate Cancer after Radiation Therapy
Challenging Cases in Robotic Radical Prostatectomy
Post-Operative Management-Erectile Function
Postoperative Management and Preoperative Considerations: Urinary Incontinence and Anastomotic Stricture.

Summary: Maull guides us step-by-step to shift our fear-based conditioning into the habits of courage, compassion, and positive change. With Radical Responsibility, he invites us to experience for ourselves the life-changing journey from victim to co-creator.

Summary: "Radical SAM Enzymes, Volume 606, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Characterization of the glycyl radical enzyme choline trimethylamine-lyase and its radical S-adenosylmethionine activating enzyme, Diphathimide biosynthesis, Radical SAM glycyl radical activating enzymes, Radical SAM enzyme BioB in the biosynthesis of biotin, Biogenesis of the PQQ cofactor, Role of MoaAC in the biogenesis of the molybdenum cofactor, Biosynthesis of the nitrogenase cofactor, Bioinformatics of the radical SAM superfamily, The involvement of SAM radical enzymes in the biosynthesis of methanogenic coenzymes, methanopterin and coenzyme F420, and more"--Publisher.

Contents:
Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain / Gemma L. Holliday, Eyal Akiva, Elaine C. Meng, Shoshana D. Brown, Sara Calhoun, Ursula Pieper, Andrej Sali, Squire J. Booker and Patricia C. Babbitt
Purification and Characterization of the Choline Trimethylamine-Lyase (CutC)-Activating Protein CutD / Smaranda Bodea and Emily P. Balskus
QueE: A Radical SAM Enzyme Involved in the Biosynthesis of 7-Deazapurine Containing Natural Products / Julia K. Lewis, Nathan A. Bruender and Vahe Bandarian
TYW1: A Radical SAM Enzyme Involved in the Biosynthesis of Wybutosine Bases / Anthony P. Young and Vahe Bandarian
Mechanistic Studies on the Radical SAM Enzyme Tryptophan Lyase (NosL) / Dhananjay M. Bhandari, Dmytro Fedoseyenko and Tadhg P. Begley
Aminofutalosine Synthase (MqnE): A New Catalytic Motif in Radical SAM Enzymology / Sumedh Joshi, Dmytro Fedoseyenko, Nilkamal Mahanta and Tadhg P. Begley
Iterative Methylations Resulting in the Biosynthesis of the t-Butyl Group Catalyzed by a B12-Dependent Radical SAM Enzyme in Cystobactamid Biosynthesis / Yuanyou Wang, Bastien Schnell, Rolf Müller and Tadhg P. Begley
Biochemical Approaches for Understanding Iron-sulfur Cluster Regeneration in Escherichia coli Lipoyl Synthase during Catalysis / Erin L. McCarthy and Squire J. Booker
Using Peptide Mimics to Study the Biosynthesis of the Side-Ring System of Nosiheptide / Bo Wang, Joseph W. LaMattina, Edward D. Badding, Lauren K. Gadsby, Tyler L. Grove and Squire J. Booker
Mechanistic Studies of Radical SAM Enzymes: Pyruvate Formate-Lyase Activating Enzyme and Lysine 2,3-Aminomutase Case Studies / Amanda S. Byer, Elizabeth C. McDaniel, Stella Impano, William E. Broderick and Joan B. Broderick
Determining Redox Potentials of the Iron-Sulfur Clusters of the AdoMet Radical Enzyme Superfamily / Stephanie J. Maiocco, Lindsey M. Walker and Sean J. Elliott
Radical S-Adenosyl-L-Methionine (SAM) Enzyme Involved in the Maturation of the Nitrogenase Cluster / Lee Rettberg, Kazuki Tanifuji, Andrew Jasniewski, Markus Walter Ribbe and Yilin Hu
Purification, Characterization, and Biochemical Assays of Biotin Synthase from Escherichia coli / Julia D. Cramer and Joseph T. Jarrett
Methods for Expression, Purification, and Characterization of PqqE, a Radical SAM Enzyme in the PQQ Biosynthetic Pathway / Wen Zhu, Ana M. Martins and Judith P. Klinman
Methods for Studying the Radical SAM Enzymes in Diphthamide Biosynthesis / Min Dong, Yugang Zhang and Hening Lin
Guidelines for Determining the Structures of Radical SAM Enzyme-Catalyzed Modifications in the Biosynthesis of RiPP Natural Products / Leah B. Bushin and Mohammad R. Seyedsayamdost
Identification of the Radical SAM Enzymes Involved in the Biosynthesis of Methanopterin and Coenzyme F420 in Methanogens / Kylie D. Allen and Robert H. White
Lessons From the Studies of a C-C Bond Forming Radical SAM Enzyme in Molybdenum Cofactor Biosynthesis / Haoran Pang and Kenichi Yokoyama.

Contents:
[1] Basic physics and instrumentation by E. H. Quimby [and others]--[2] Medicine, by S. S. Silver.

Summary: This book presents new information on radiobiology that more clearly refutes the linear no-threshold (LNT) assumption and supports radiation hormesis. Fresh light is cast on the mechanisms of radiation hormesis and the potential benefits of low-dose ionizing radiation in preventing and treating a wide variety of inflammatory and proliferative diseases. It is proposed that these effects may derive from cellular communication via electromagnetic waves directed by DNA, with each cell acting as a quantum computer. Readers will also find close analysis of the negative impacts of radiophobia on many aspects of modern life, including attitudes to imaging technologies, licensing of nuclear power reactors, and preparedness for survival of nuclear war. The book will be of interest to researchers and scientists in radiobiology, radiation protection, health physics, medical physics, and radiology. Specifically, it will provide medical physicians, radiation oncologists, radiation epidemiologists, gerontologists, cell biologists, toxicologists, and nuclear engineers with a wide range of interesting facts and enlightening novel perspectives. -- publisher's website.

Contents:
Movers of radiation hormesis
Radiological weapons
The harmful and fraudulent basis for the LNT assumption
Thresholds
Plutonium particle toxicity myth
Wonderful radon
Benefits in disease prevention, control, and cure
Heuristic view on quantum bio-photon cellular communication.

Contents:
Physics and chemistry of radiation absorption
Molecular mechanisms of DNA and chromosome damage and repair
Cell survival curves
Radiosensitivity and cell age in the mitotic cycle
Fractionated radiation and the dose-rate effect
Oxygen effect and reoxygenation
Linear energy transfer and relative biologic effectiveness
Acute radiation syndrome
Medical countermeasures to radiation exposure
Radiation carcinogenesis
Heritable effects of radiation
Effects of radiation on the embryo and fetus
Radiation cataractogenesis
Radiologic terrorism
Doses and risks in diagnostic radiology, interventional radiology and cardiology, and nuclear medicine
Radiation protection
Molecular techniques in radiobiology
Cancer biology
Dose-response relationships for model normal tissues
Clinical response of normal tissues
Model tumor systems
Cell, tissue, and tumor kinetics
Time, dose, and fractionation in radiotherapy
Retreatment after radiotherapy: the possibilities and the perils
Alternative radiation modalities
The biology and exploitation of tumor hypoxia
Chemotherapeutic agents from the perspective of the radiation biologist
Hyperthermia.

Contents:
Introduction and Background
The "Radio-resistance" of Glioblastoma in the Clinical Setting, and the Present Therapeutic Options
Radiobiological Hints from Clinical Studies
Chemo-radiotherapy: Radiation Total Dose and Fractionation
Clinical Evidence and Radiobiological Background of Particle Radiation Therapy
Mathematical Modeling of Radiobiological Parameters from Clinical Studies
Clinical, Pathology and Molecular Prognostic Parameters of Response to Chemo- and Radiotherapy from Clinical Series
Radiation Tolerance of Normal Brain: QUANTEC 2010 and Beyond
Basic Knowledge of Glioblastoma Radiobiology
Molecular Radiobiology and Mathematical Modeling
Genetic and Epigenetic Determinants in Tumor Initiation and Progression
Tumor Microenvironment
Cell Death Pathways, with Special Regard to Ionizing Radiation and Temozolomide Therapy
mi-RNA Manipulation in Modifying Radiation Sensitivity in Glioblastoma Models
Glioma Stem-like Cells and Radiation Resistance
Hypoxia and Radiation Resistance
Invasiveness and Radiation Failures
Nanoparticle Technology for Research Radiobiology
The Molecular Classification of Glioblastoma as a Translational Instrument
Translational Perspectives for Gene Therapy
Pre-Clinical Models of Glioblastoma in Radiobiology: Evolving Protocols and Research Methods
From Molecular to Clinical Radiation Biology
Perspectives of the Large Data-Bases and Ontologic Models of Correlation of Pre-clinical and Clinical Results
Conclusive Remarks and Perspectives for Future Research.

Summary: Investigates radiocesium movement in all major components of forest ecosystems, e.g. the plants, animals, insects, microorganisms, and soils, during the initial stage of contamination after the incident at Fukushima Daiichi Nuclear Power Plant. Most of the work was conducted at a common research site. More specifically, the book examines the contribution of surface uptake by trees in the dynamics of radiocesium during the initial contamination stage; the movement of radiocesium in the form of small organic fragments that are essential to the radiocesium dynamics in forest ecosystems; and the upward movement of radiocesium due to microorganism activity, which promotes the effective decontamination of the forest floor. Lastly, it explains why spiders could be a valuable indicator of the contamination level in forest ecosystems.

Contents:
Part I: Radiocesium deposition at the accident
Chapter 1: Radioactive contamination in forest by the accident of Fukushima Daiichi Nuclear Power Plant
Comparison with Chernobyl-
Chapter 2: Radiocesium deposition at the accident and the succeeding movement through hydrological process in forest ecosystem in Fukushima
Part II: Mechanisms of radiocesium translocation in plants
Chapter 3: Uptake of radiocesium by plants
Chapter 4: Surface absorption of 137Cs through tree bark
Chapter 5: Translocation of 137Cs in the woody parts of Sugi (Cryptomeria japonica)
Chapter 6: Radiocesium translocations in bamboos
Chapter 7: Movement of cesium in model plants
Part III: Radiocesium movement through ecological processes in forest ecosystem
Chapter 8: Movement of radiocesium as litterfall in deciduous forests
Chapter 9: Changes in chemical forms of radiocesium in the forest floor organic matter with decomposition, and uptake of radiocesium derived from the organic matter by crops
Chapter 10: Contamination and transfer of radio-Cs in soil ecosystem
Chapter 11: Spiders as an indicator of 137Cs dynamics in the food chains in forests
Chapter 12: Radioactive cesium contamination of sika deer in Oku-Nikko region of Tochigi Prefecture in Central Japan
Part IV: Radiocesium dynamics and its perspective in forests
Chapter 13: Modeling radiocesium dynamics in a contaminated forest in Japan
Chapter 14: Future perspective.

Contents:
Diagnosis of small Hepatocellular carcinoma
Pathobiologic characteristics of small hepatocellular carcinoma
Radiofrequency ablation systems and operating mechanisms
Initial Clinical Assessment and Patient Selection
Percutaneous Radiofrequency Thermal Ablation
Laparoscopic and Open RFA
Peri-RFA care and management of complications
Combined therapies of RFA
Radiological assessment and follow-up after radiofrequency
Adjuvant therapy after Radiofrequency Ablation
Surgery vs Radiofrequecy Ablation for Small Hepatocellular Carcinoma.

Summary: Radiofrequency Augmentation Techniques, part of the Atlas of Interventional Pain Management series, is a concise, practical guide that provides clinicians with detailed, step-by-step guidance on how to perform the latest interventional techniques for treating patients with chronic pain. This comprehensive, easy-to-follow guide offers expert coverage of how to deliver safe, accurate, and cost-effective pain relief to patients using all clinically useful imaging modalities, including ultrasound-guided techniques and fluoroscopy. With high-quality images and clear, authoritative guidance throughout, it shows exactly how to evaluate the causes of pain, identify the most promising stimulation technique, locate the site with precision, and deliver effective relief.

Contents:
History of radiofrequency ablation (RFA)
Mechanism of action
Patient selection, indications, and contraindications
Perioperative management
Cervical medical branches
Thoracic medical branches
Lumbar medical branches
Radiofrequency ablation involving the sacroiliac joint
Radiofrequency ablation of hip joint articular nerves
Knee joint
Ankle joint articular nerves
Shoulder joint
Radiofrequency ablation and pulsed radiofrequency of the upper extremities
Radiofrequency ablation and pulsed radiofrequency of the lower extremities
Radiofrequency ablation for headache
Radiofrequency ablation and pulsed radiofrequency ablation for the sympathetic nervous system
Radiofrequency ablation of the medical branch in the presence of other devices
Radiofrequency ablation complications and management
Measuring outcomes.

Summary: Radiofrequency (RF) has been used in many areas of medicine for some time, but only gained popularity in aesthetics in the early 2000s. Although initial procedures provided variable results, the field of RF has grown dramatically. Currently, a multitude of devices which offer an array of technologies, each geared to specific applications, are on the market. In this book, a comprehensive discussion of the evolving area of RF is provided, and the current and cutting-edge technologies which span from noninvasive treatments of facial wrinkles to invasive body contouring procedures are discussed in detail. The methodologies covered include thermal and ablative modalities, volumetric and fractional approaches, as well as practical aspects of application in clinical practice. Included are also pearls on patient management and prevention and treatment of complications. Finally, RF-based procedures are compared with equivalent laser and surgical approaches in a risk-benefit evaluation. Reviewing the standard of care for RF-based treatments and providing information relevant for clinical decision-making and practice management, this publication is a valuable tool for dermatologists, plastic surgeons and all practitioners who use or are contemplating the introduction of RF into practice.

Summary: This book describes the principles and applications of radiofrequency treatments for various spinal indications, including disc herniation, discogenic and radicular pain, facet joint arthropathy, and benign and malignant lesions of the vertebral column. The aim is to provide a handy guide that will acquaint readers with all aspects of radiofrequency neurotomy at different levels of the spine, enabling them to carry out treatments effectively and safely. Radiofrequency neurotomy, or radiofrequency ablation, is a minimally invasive procedure that is associated with a reduction in complications, side effects, and risks of anesthesia as well as with lower costs. This book, written by world-renowned authorities in the field, fills a significant gap in the literature by specifically focusing on the use of radiofrequency for spinal conditions. It will be of value to a range of specialists, including interventional neuroradiologists and radiologists, neurosurgeons, and orthopedists.

Contents:
I. Pulmonary tuberculosis
II. Non-tuberculous affections.

Contents:
Part 1 Introduction
The History of Radioguided Surgery: Early Historical Milestones and the Development of Later Innovative Clinical Applications
Part 2 Detailed Methodology Part
Physics of Radioguided Surgery
The use of intraoperative small and large field of view gamma cameras for radioguided surgery
Surgical Navigation
Tracers applied in radioguided surgery
Radiation Safety and Dosimetry
Part 3 Clinical Application: Breast
Radioguided sentinel lymph node mapping and biopsy in breast cancer
Radioguided Surgery for Non-Palpable Breast Lesions: I-125 Radioactive Seed Localization.- Radioguided Surgery for Non-Palpable Breast Lesions: Technetium-99m Radioguided Occult Lesion Localization (ROLL)
Part 4 Clinical Application: Skin
Radioguided sentinel lymph node mapping and biopsy in cutaneous melanoma
Part 5 Clinical Application: Head and Neck
Sentinel lymph node mapping and biopsy in oral cancer
Part 6 Clinical Application: Thyroid and Parathyroid
Radioguided sentinel lymph node mapping and biopsy in thyroid cancer
Radioguided Parathyroid Surgery
Radioguided surgery of thyroid carcinoma recurrences
Part 7 Clinical Application: Urogenital Tract
Radioguided sentinel lymph node biopsy and lymphatic mapping in urogenital malignancies
Radioguided sentinel lymph node mapping and biopsy in Gynaecological malignancies
Part 8 Clinical Application: Gastrointestinal Tract
Radioguided sentinel lymph node mapping and biopsy in oesophago-gastric
Radioguided sentinel lymph node mapping and biopsy in colorectal cancer
Radioguided surgery in gastro-entero-pancreatic neuroendocrine tumors
Part 9 Clinical Application: Thoracic
Radioguided sentinel lymph node mapping and biopsy in non-small-cell lung cancer (NSCLC)
Radioguided surgery of small pulmonary nodules
Part 10 Miscellaneous
Radioguided localization of bone lesions
Radioguided monitoring of systemic leakage during isolated limb perfusion
Radioimmunoguided Surgery: Intraoperative radioimmunodetection for the radioguided localization and resection of tumors
18F-FDG-Directed Surgery and 18F-FDG-Directed Interventional Procedures
Part 11 Outlook: New techniques, image fusion, optical imaging
Fluorescent tracers, hybrid tracers
Magnetic Advances in Cancer Surgery
Ultrasound fusion
Part 12 Examples (conventional techniques and innovations). .

Contents:
pt. 1. Theory
pt. 2. Experiments
pt. 3. Neutron Experiments.

Contents:
Part 1: Physics
Part 2: Non-interpretive skills
Part 3: Biostatistics
Parrt 4: Rapid Review.

Summary: "High-yield, image-rich study guide presents complex physics concepts in reader-friendly format Physics is a key component of the American Board of Radiology core and certifying exams, therefore it is an essential area of study for radiology residents and young radiologists prepping for these exams. Radiology residents gather their medical physics knowledge from many sources, often beginning with their first encounter of a radiologic image. As such, Radiologic Physics Taught Through Cases by Jonathon A. Nye and esteemed contributors incorporates an image-rich, case-based layout conducive to learning challenging physics concepts. The book encompasses physical diagnostic radiology scenarios commonly encountered during residency in a format that fosters learning and is perfect for board preparation. Seven technology-specific chapters cover fluoroscopy, mammography, computed tomography, magnetic resonance imaging, nuclear medicine, ultrasound imaging, and image processing. Each chapter features 10 succinct case-based topics intended to quickly convey information. Key Highlights: Every chapter starts with a general introduction, followed by case background, images, findings, and a brief explanation of the physical factors underlying the image's creation and displayed contrast Schematics detail important radiation safety topics, such as potential occupational or patient hazards related to fluoroscopic-guided procedures End-of-chapter references provide inspiration for further study. Review questions with correct answers at the end of each chapter reinforce key concepts This is a must-have resource for residents prepping for the radiology core exam review and early-career radiologists looking for a robust study guide for radiology certification exam review"-- Provided by publisher.

Contents:
Fluoroscopy / Rebecca Milman Marsh and Michael Silosky
Mammography / Ingrid S. Reiser
Computed Tomography / Karen L. Brown and Jason R. Gold
Magnetic Resonance Imaging / Puneet Sharma
Nuclear Medicine / Jonathon A. Nye, James Galt, and John N. Aarsvold
Ultrasound Imaging / Zheng Feng Lu
Image Processing / Jonathon A. Nye and Randahl C. Palmer.

Contents:

v. 1. 1500 Multiple choice questions and referenced, selected explanatory answers; plus pretest and post-test examinations.

Summary: Three years after the publication of the first edition, Radiological Anatomy for FRCR Part 1 remains the best seller in its category based on its faithful representation of the examination. This second edition is designed to reflect the change in exam format introduced in spring 2013. It includes two new chapters as well as some new cases in the remaining chapters and tests. Under the new exam format, candidates will be presented with 100 cases, with a single question per case and a single mark for the correct answer. This book covers all core topics addressed by the exam in a series of tests and includes chapters focussing specifically on paediatric cases and normal anatomical variants. The answers to questions, along with explanations and tips, are supplied at the end of each chapter. Care has been taken throughout to simulate the exam itself. The book aims not to replace the already available literature on radiological anatomy but rather to complement it as a revision guide. It will help candidates to identify the level of anatomical knowledge expected by the Royal College of Radiologists.

Summary: This book, now in its second edition, provides a comprehensive analysis of imaging of the kidneys, upper urinary tract, and ureters, covering the normal anatomy and anatomic variants as well as all renal and urinary system pathologies. The relevant imaging modalities are first discussed, with detailed description of their applications in the kidney and upper urinary tract. The entire spectrum of kidney pathologies is then presented in a series of detailed chapters with up-to-date references, high-quality images, informative schemes, and figures showing macroscopic and microscopic surgical and pathologic specimens. Chapters relating to the latest innovations in tumor ablation, vascular and nonvascular interventional procedures, and parametric and molecular imaging have been fully updated to reflect progress in these rapidly evolving fields. This book will be of great interest to all radiologists, oncologists, nephrologists, and urologists who are involved in the management of kidney pathologies in their daily clinical practice.

Contents:
Embryology and development of the Kidney
Normal Radiological Anatomy and Anatomical Variants of the Kidney
Normal Radiological Anatomy of the Retroperitoneum
Imaging and Interventional Modalities: Ultrasound of the Kidney
Computed Tomography
Magnetic Resonance Imaging
Nuclear Medicine
Biopsy
Vascular Interventional Radiology
Non-vascular Interventional Radiology
Non-Tumoral Pathology: Congenital and Development Disorders of the kidney
Renal Cystic Disease
Renal Parenchymal Diseases
Obstructive Uropathy, Pyonephrosis and Reflux Nephropathy in adults
Nephrolithiasis and Nephrocalcinosis
Acute Renal Infections
Chronic renal infections and renal fungal infections
Renal Vascular Pathologies
Imaging of Renal Trauma
Tumoral Pathology: Benign Solid Renal Tumors
Renal Cell Carcinoma
Rare and Secondary Tumors of the Kidney and Renal Pseudotumors
Radiofrequency ablation and cryoablation for renal cell carcinoma
Urinary tract tumors
Renal Lymphoma and Renal Sarcomas
Cystic Renal Masses. Special Topics: The Pediatric Kidney
The Kidney in the Elderly
Renal Failure
Renal Transplant
Imaging of Dialysis
Imaging of the Postoperative Kidney
Contrast Media
Induced Nephropathy and Nephrogenic Systemic Fibrosis
Functional Imaging of the Kidney
Molecular Imaging and Tumoral Antigen Targeting
Research Perspectives and Future Trends in Renal Imaging.

Summary: This book provides a state-of-the-art review of the technical and clinical aspects of the vascular interventional radiological (IR) procedures currently employed in obstetrics and gynaecology. A particular focus is on uterine artery embolisation for fibroid disease, which is contrasted with the main alternative uterus-conserving surgical approach of myomectomy, and with ablation therapy. Detailed consideration is also given to the role of embolisation in a variety of other less common conditions, including arteriovenous malformations, post-partum haemorrhage, abnormal placentation and pelvic congestion syndrome. IR procedures are examined from a critical gynaecological perspective and with regard to surgical alternatives. The authors include leading interventional radiologists and gynaecologists from the United Kingdom, Europe and North America. .

Contents:
The History and Epidemiology of Fibroids
The Medical Treatment of Uterine Fibroids
Clinical Presentation of Uterine Fibroids
Gynecological Assessment Prior to Uterine Artery Embolization
Imaging Fibroids Pre and Post Uterine Artery Embolisation
Uterine Artery Embolization Indications and Contraindications
Clinical Results of Fibroid Embolisation, Trials and Registries
Complications of Fibroid Embolisation
When to Consider Ovarian Artery Embolization in UAE
Early Post UAE Management
Postembolization Problems and Management
The Role of a Repeat UAE Procedure
Myomectomy Techniques
Myomectomy: Results and Complications
Myomectomy Following UAE
UAE is not Recommended for Women Wishing to Conceive
Costing Issues and UAE in the Developing World
Who Can and Should do Uterine Artery Embolisation
Is There a Place for UAE in Adenomyosis?
The Role of Magnetic Resonance Guided Focused Ultrasound for Uterine Fibroids
Obstetric Management of Postpartum Haemorrhage
The Role of Interventional Radiology in the Management of Abnormal Placentation
Pelvic Venous Congestion
Embolization in Pelvic Congestion Syndrome.

Summary: Radiological Safety and Quality - Paradigms in Leadership and Innovation is a multi-disciplinary and inter-sectorial collaboration by international experts and leaders from academic institutions, radiology practices, professional organizations, regulatory authorities, UN and international agencies. Established principles and new concepts, challenges and opportunities, and examples of leadership and innovations are discussed to raise awareness, share experience and facilitate development of facility-based or system-wide improvements in radiation safety, quality radiology, and patient care by procedure justification, optimization of protection and imaging data, and incident minimization. The 26 chapters by 53 experts and 11 messages from international organizations and agencies convey a common theme: there is no single panacea to improve radiological safety and quality but on-going leadership, innovation, collaboration, and stakeholder participation are needed.

Contents:
Radiological Safety and Quality
Procedure Justification, Protection Optimization, and Error Reduction
Infrastructure Improvements
Global, Regional and National Challenges, Actions and Opportunities.

Contents:
1. Introduction
2. Diagnostic Imaging
3. Radiation Safety
4. X-rays and X-ray Tubes
5. Ultrasound
6. CT
7. MRI
8. Nuclear Medicine
9. Contrast Materials
10. Chest Overview
11. Cardiac
12. Abdomen
13. Acute Abdomen
14. Gastrointestinal Tract
15. Hepatobiliary System
16. Pancreas
17. Urinary Tract
18. Staging Cancer
19. Musculoskeletal
20. Severe Trauma Basics
21. Mammography
22. Interventional
23. Neuroradiology
24. Acute Care Chest
25. Midterm Quiz.

Contents:
1. Subtotal nephrectomy and tumour ablation
2. Renal transplantation
3. Imaging after endo-urological stone treatment
4. Pelvi-ureteric junction reconstruction
5. Retroperitoneal fibrosis
6. Urinary diversion
7. Ureteric reconstruction and replacement
8. Conservative and reconstructive bladder surgery
9. Bladder augmentation in children
10. Radiology and follow-up of the neobladder
11. General consequences of lower urinary tract replacement and reconstruction
12. Surgery on the benign prostate
13. Imaging after treatment of prostate cancer
14. Urethroplasty
15. The postoperative appearance and follow-up of urinary tract prostheses
Index.

Summary: Reading PET/CT scans is sometimes challenging. Not infrequently, abnormal findings on CT images are functionally silent and therefore difficult for nuclear medicine practitioners to interpret. Furthermore, in general only a low-dose CT scan is produced as part of the combined PET/CT study, and the resulting CT images may prove suboptimal for image interpretation. This atlas is designed to enable nuclear medicine practitioners who routinely read PET/CT scans to recognize the most common CT abnormalities. Slice-by-slice descriptions are provided of anatomical structures as visualized on CT scans obtained in PET/CT studies. The CT findings that may be detected while reviewing PET/CT scans of various body regions and conditions are then illustrated and fully described. The concluding section of the book is devoted to the principal MRI findings in diseases which cannot be evaluated using PETs/CTs.

Contents:
Normal CT slice by slice: Brain
Head and neck
Thorax
Abdomen
Pelvis
Para-physiological CT findings: Brain
Head and neck
Thorax
Abdomen
Pelvis
Pathologic CT findings: Brain
Head and neck
Thorax
Abdomen
Pelvis
MR for nuclear medicine: Brain
Bone
Pelvis.

Summary: This atlas is intended to enable nuclear medicine practitioners who routinely read PET/CT scans to recognize the most common CT abnormalities. Reading PET/CT scans can sometimes be challenging. It is not infrequent, in fact, to encounter abnormal findings in CT images (not related to the neoplastic disease under evaluation) that are functionally silent and therefore difficult to interpret for nuclear medicine practitioners. Frequently, these findings are clinically relevant and should be reported, interpreted and compared to previous scans. This may also have an impact on patient management, since expensive tests like PET/CT are expected to provide the highest level of diagnostic information. Generally, CT images associated with a PET scan are acquired in a low-dose modality, and therefore prove to be sub-optimal for CT image interpretation. Sometimes a comparison with a full-resolution and contrast-enhanced CT atlas may be difficult. Low-dose CT slices are thicker than diagnostic CT and offer less anatomical detail, which can affect accuracy in terms of recognizing both anatomical structures and pathological findings. Today it is becoming increasingly common to acquire a standard PET/CT by combining the administration of contrast media and a diagnostic CT; here, too, basic CT reporting skills are needed in clinical practice. This atlas features a chapter on "normal anatomy" (with and without contrast media) that is based on low-dose and full-dose CT images from PET/CT standard acquisition, and which identifies all the relevant anatomical structures. Other chapters (focusing on the thorax, abdomen, pelvis, and musculoskeletal system) present cases with common and uncommon anatomical abnormalities. The addition of new cases with ceCT in this revised second edition rounds out the coverage of PET/CT reporting. Given its scope, the book will be of interest to nuclear medicine physicians, radiologists, and oncologists alike.

Contents:
Chapter 1: Normal Anatomy
Chapter 2: Head & Neck
Chapter 3: Thorax
Chapter 4: Abdomen
Chapter 5: Pelvis
Chapter 6: Musculoskeletal.

Summary: This book is a concise introduction to the dynamic field of radiology and provides readers with general examples and brief discussions of basic radiographic principles. Introductory chapters present fundamental scientific concepts underlying the medical use of imaging modalities and technology, including ultrasound, computed tomography, magnetic resonance imaging, and nuclear medicine. Subsequent chapters are organized by anatomic region and imaging modality that highlight the radiologist?s role in diagnosing and treating common disorders. This revised edition is thoroughly updated and includes new or expanded chapters on nuclear medicine and pediatric radiology. Radiology Fundamentals, Fifth Edition, is a premier self-directed learning resource for medical students, non-radiology housestaff, physician assistants, nurse practitioners, radiologist assistants and other allied health professionals.

Contents:
Part 1. Introductory Section
Chapter 1. Radiation Safety and Risk
Chapter 2. Introduction to Radiology Concepts
Chapter 3. Conventional Radiology
Chapter 4. Ultrasound
Chapter 5. Computed Tomography
Chapter 6. MRI
Chapter 7. Introduction to Nuclear Medicine
Chapter 8. Cardiovascular and Interventional Radiology
Part 2. Chest Section
Chapter 9. Heart and Mediastinum
Chapter 10. Coronary CTA
Chapter 11. Lateral Chest
Chapter 12. Pulmonary Mass Lesions
Chapter 13. Air Space Disease
Chapter 14. Interstitial Disease
Chapter 15. Atelectasis
Chapter 16. Pulmonary Vasculature
Chapter 17. Pulmonary Edema
Chapter 18. Pulmonary Embolism
Chapter 19. Pneumothorax
Chapter 20. Miscellaneous Chest
Chapter 21. Tubes and Lines
Part 3. Women's Section
Chapter 22. Breast Imaging
Chapter 23. Women?s Ultrasound
Chapter 24. Women's Health Interventions
Part 4. Abdominal Section
Chapter 25. Abdominal Calficiations
Chapter 26. Abdominal Harware and Tubes
Chapter 27. Abnormal Air Collections of Abdomen
Chapter 28. Bowel Obstruction
Chapter 29. Concerning Abdominal Masses
Chapter 30. Fluoroscopic Evaluation of the Upper GI Tract and Small Bowel
Chapter 31. Imaging of the Colon
Chapter 32. Imaging of the Gallbladder
Chapter 33. Incidental Abdominal Lesion
Chapter 34. Inflammatory and Infections Bowel Disease
Chapter 35. Intra-abdominal Lymphadenopathy
Part 5. Nuclear Medicine Section
Chapter 36. Nuclear Medicine Cardiac Imaging
Chapter 37. Gastrointestinal Nuclear Medicine
Chapter 38. Oncological Nuclear Medicine
Chapter 39. Pulmonary Nuclear Medicine
Chapter 40. Skeletal Nuclear Medicine
Part 6. Interventional Radiology Section
Chapter 41. Diagnostic Arteriography
Chapter 42. Pulmonary Arteriography and IVC Filter Placement
Chapter 43. Percutaneous Nephrostomy Placement
Chapter 44. TIPS
Chapter 45. Central Venous Access
Chapter 46. Interventional Oncology
Part 7. Musculoskeletal Section
Chapter 47. Fractures 1
Chapter 48. Fractures 2
Chapter 49. Bone Tumor Characteristics
Chapter 50. Arthritis
Part 8. Neuroradiology Section
Chapter 51. CNS Anatomy
Chapter 52. The Cervical Spine
Chapter 53. Head Trauma
Chapter 54. Stroke
Chapter 55. Headache and Back Pain
Part 9. Pediatrics Section
Chapter 56. Pediatric Radiology Pearls.

Summary: This book serves as an introduction to the dynamic field of radiology for medical students, non-radiology house staff, physician assistants, nurse practitioners, radiology assistants, and other allied health professionals and provides information that ranges from basic radiographic principles to advanced imaging techniques. It begins with a discussion of the fundamental concepts underlying the medical use of imaging modalities such as ultrasound, computed tomography, magnetic resonance imaging, and nuclear medicine. Subsequent chapters are organized by anatomic region and imaging modality that highlight the radiologists role in diagnosing and treating common disorders. Each chapter offers learning objectives to aid readers in recognizing important points and connecting the basic radiology concepts. The sixth edition is thoroughly updated. The editors and authors introduce the approach to SAFE radiology, explaining the concepts of S-safety in all modalities, A-appropriateness of imaging ordering, F-interpreting films and E-acting expeditiously on significant findings and executing the recommendation of the imaging findings. Easy to learn and easy to remember, SAFE reminds all health care professionals that safety and appropriateness should precede any imaging testing and that all results should be applied expeditiously and thoughtfully.

Summary: The nutcracker phenomenon (NCP) is an accentuated phenomenon of normal subtle compression of the left renal vein (LRV) between the abdominal aorta and superior mesenteric artery. The nutcracker syndrome (NCS) is a syndrome caused by NCP, resulting in hematuria, proteinuria, or left flank pain. The established diagnostic criterion of NCP is a pressure gradient more than 3 mmHG across the compression site, and NCS has been known to be rare, but probably is not rare and in fact quite common. The most important reason why NCS is known to be rare is that the diagnosis is difficult unless invasive venous catheterization and pressure measurement confirm the pressure gradient. Doppler ultrasound is useful in measuring the flow velocity of LRV. From the velocity measured by Doppler ultrasound, we may estimate the pressure gradient. Doppler ultrasound of LRV needs technical skills and experience. Computed tomography (CT) is a popular imaging technique for patients with hematuria, and we need to be familiar with the findings of the NCP at CT. There are variations of NCP associated with vascular anatomy and posture of the patients. This book will illustrate the concepts of NCP and NCS, findings at Doppler ultrasound and CT, and variations of NCP.

Contents:
1 Introduction
2 Nutcracker Phenomenon (NCP) and Nutcracker Syndrome (NCS)
3 Prevalence of NCP and NCS
4 Left Renal Vein (LRV)
5 Diagnostic Techniques and Criteria
6 Doppler Ultrasound
7 CT and MRI Findings
8 Subtypes of NCP and NCS
9 NCP associated with Congenital Variations of LRV and IVC
10 Postural Variations of NCP and NCS
11 Other Variations of NCP and NCS
12 Severe NCP, Occlusion of LRV
13 NCP and NCS in Members of the Same Family
14 NCP-related or associated diseases
15 Management of NCS
16 Asymptomatic hematuria and proteinuria.

Summary: Illustrates how to achieve reliable diagnoses when confronted by the different abnormalities, or disease patterns, that may be visualized on CT scans of the chest.

Contents:
Part I. Focal lung diseases
part II. Diffuse lung diseases
part III. Application of disease pattern and distribution, and radiologic signs to the differentiation of various lung diseases.

Contents:
Part 1. Pharynx/Esophagus
1. Benign structural and functional abnormality of the esophagus, postop. Complication of the esophagus
2. Esophagitis
3. Benign and malignant tumor of the esophagus
Part 2. Stomach/Duodenum
4. Benign structural & functional abnormality of the stomach and duodenum
5. Inflammatory and infectious diseases of the stomach and duodenum
6. Mucosal tumor of the stomach
7. Subepithelial tumor of the stomach
8. Lymphoma and metastasis of the stomach
9. Postoperative change and complications of the stomach and duodenum
Part 3. Small Bowel
10. Benign structural & functional abnormality of the small bowel
11. Inflammatory disease of the small bowel
12. Vasculitis and ischemic bowel disease
13. Small bowel obstruction
14. Benign tumor of the small bowel
15. Malignant tumor of the small bowel
Part 4. Colon
16. Benign structural & functional abnormality of the colon
17. Inflammatory & infectious disease of the colon
18. Benign tumor of the colon
19. Malignant tumor of the colon
20. Postoperative change and complications of the colon
Part 5. Mesentery, Peritoneum, abdominal wall
21. Benign diseases of mesentery and omentum
22. Malignant diseases of mesentery and omentum
23. Abdominal wall abnormality & hernia.

Summary: Radiology Illustrated: Hepatobiliary and Pancreatic Radiology is the first of two volumes that will serve as a clear, practical guide to the diagnostic imaging of abdominal diseases. This volume, devoted to diseases of the liver, biliary tree, gallbladder, pancreas, and spleen, covers congenital disorders, vascular diseases, benign and malignant tumors, and infectious conditions. Liver transplantation, evaluation of the therapeutic response of hepatocellular carcinoma, trauma, and post-treatment complications are also addressed. The book presents approximately 560 cases with more than 2100 carefully selected and categorized illustrations, along with key text messages and tables, that will allow the reader easily to recall the relevant images as an aid to differential diagnosis. At the end of each text message, key points are summarized to facilitate rapid review and learning. In addition, brief descriptions of each clinical problem are provided, followed by both common and uncommon case studies that illustrate the role of different imaging modalities, such as ultrasound, radiography, CT, and MRI.

Contents:
Part 1. Liver
Anomalies and Anatomic Variants of the Liver
Diffuse Liver Disease
Benign Tumors of the Liver
Hepatocellular Carcinoma
Other Malignant Tumors of the Liver
Focal Hepatic Infections
Hemodynamic and Perfusion Related Disorders
Liver Transplantation
Therapeutic Response Evaluation of HCC
Trauma and Post-treatment Complications of the Liver
Part 2. Biliary tract
Anomalies and Anatomic Variants of the Biliary tract
Cholangitis
Cholecystitis
Cholangiocarcinoma
Tumors of the Gallbladder
Trauma and Post-treatment Complications of the Biliary tract
Part 3. Pancreas
Anomalies and Anatomic Variants of the Pancreas
Pancreatitis
Cystic Tumors of the Pancreas
Solid Tumors of the Pancreas
Trauma and Post-treatment Complications of the Pancreas
Part 4. Spleen
Anomalies and Anatomic Variants of the spleen
Diffuse Spleen Disease
Benign Focal Lesions of the Spleen
Malignant Focal Lesions of the Spleen
Trauma and Post-treatment Complications of the spleen.

Summary: This case-based atlas presents images depicting the findings typically observed when imaging a variety of common and uncommon diseases in the pediatric age group. The cases are organized according to anatomic region, covering disorders of the brain, spinal cord, head and neck, chest, cardiovascular system, gastrointestinal system, genitourinary system, and musculoskeletal system. Cases are presented in a form resembling teaching files, and the images are accompanied by concise informative text. The goal is to provide a diagnostic reference suitable for use in daily routine by both practicing radiologists and radiology residents or fellows. The atlas will also serve as a teaching aide and a study resource, and will offer pediatricians and surgeons guidance on the clinical applications of pediatric imaging.

Contents:
Congenital Anomalies of the Brain and Spinal Cord
Metabolic Diseases of the Brain
Infection and Inflammatory Diseases of the Central Nervous System
Neoplasms of the Brain and Spine
Brain and Spine Injury and Cerebral Vascular Disorders
Neurosonography
Congenital Malformations of the Head and Neck
Infectious and Traumatic Diseases
Neoplasms of the Head and Neck
CT Findings of Congenital Lung Malformations
Neonatal Chest Imaging
Pediatric Airway Disorders
Infections
Tumors of the Pediatric Chest
Pediatric Diffuse Lung Disease
Pediatric Cardiac Imaging I: CT and MR Techniques
CT and MRI Findings of Cardiac Defects in Congenital Heart Disease
Congenital Thoracic Vascular Anomalies and Associated Airway Diseases
Congenital and Neonatal Gastrointestinal Diseases
Non-neonatal Gastrointestinal Diseases
Inflammation, Infection, and Neoplasms in the Abdomen
Liver, Biliary Tract, Pancreas, and Spleen
Congenital Anomalies of the Upper Urinary Tract
Cystic Renal Disease and Neoplasms
Urinary Tract Infection
Bladder and Urethra Disease
Pediatric Uterus, Ovary, and Testis Diseases
Genetic Skeletal Disorders
Soft Tissue Diseases
Pediatric Skeletal Trauma
Infection and Inflammation of the Musculoskeletal System
Pediatric Bone Tumors
Pediatric Hip Disorders
Miscellaneous Musculoskeletal Disease.

Summary: Radiology Illustrated: Spine is an up-to-date, superbly illustrated reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. Common, critical, and rare but distinctive spinal disorders are described succinctly with the aid of images highlighting important features and informative schematic illustrations. The first part of the book, on common spinal disorders, is for radiology residents and other clinicians who are embarking on the interpretation of spinal images. A range of key disorders are then presented, including infectious spondylitis, cervical trauma, spinal cord disorders, spinal tumors, congenital disorders, uncommon degenerative disorders, inflammatory arthritides, and vascular malformations. The third part is devoted to rare but clinically significant spinal disorders with characteristic imaging features, and the book closes by presenting practical tips that will assist in the interpretation of confusing cases.

Contents:
Part I. Basic step: Common spinal disorders
Chapter 1. Anatomical considerations of the spine
Chapter 2. Common spine disorders associated with back pain
Chapter 3. Common spine disorders associated with neck pain
Chapter 4. Common traumatic disorders of the thoracolumbar spine
Chapter 5. MR imaging of spinal bone marrow
Chapter 6. Common normal structures and MR imaging artifacts of the spine that may mimic pathology
Chapter 7. Post-operative Imaging
Part II. Intermediate step: Critical spinal disorders
Chapter 8. Infectious spondylitis
Chapter 9. Cervical trauma
Chapter 10. Spinal cord disorder
Chapter 11. Spinal tumor
Chapter 12. Congenital disorder
Chapter 13. Uncommon degenerative disorder
Chapter 14. Inflammatory arthritides
Chapter 15. Spinal Vascular Malformation
Part III. Rare but characteristic spinal disorders
Chapter 16. Rare but characteristic spinal disorders: Musculoskeletal
Chapter 17. Rare but characteristic spinal disorders: Neural
Chapter 18. Rare but characteristic spinal disorders: Miscellaneous
Part IV. Practical tips for common confusing disorders.

Summary: "The only book of its kind to prepare radiology residents interested in working on global health service projects in the developing world Includes information on designing, testing, and deploying clinical strategies adapted for regions with limited resources Presents information technology models to support digital imaging in the developing world This book is designed to increase awareness of the global health problem of lack of access to medical imaging services and presents solutions to overcome disparities in the delivery of radiologic services to the developing world. Featuring an interdisciplinary framework, it discusses economic strategies for sustainable radiology; public health radiology for population-based approaches; clinical model formulation tailored to needs and resources of regions and communities; technology innovation and optimization; and public policy for healthcare system development at the government and international institutional level. It explores the role of radiology in addressing health care disparities and highlights strategies for radiology services planning and implementation in low resource settings. It also provides an overview of the clinical role of medical imaging in the developing world, including epidemiology, disaster response, and specific clinical applications for recognizing and managing illnesses unique to the developing world. Radiology in Global Health: Strategies, Implementation, and Applications examines ways to achieve sustainable long-term imaging strategies for limited resource regions and is a valuable resource for radiologists, radiology residents, radiology technologists, physicians, nurses, and healthcare administrators"--Provided by publisher.

Contents:
Introduction
Radiology Overview: Defining Radiology and Stakeholders in the Radiology Enterprise
Access to Imaging Technology in the Developing World
Radiology Readiness [TM], Research and Relationship Development
Economics of Sustainable Radiology in the Developing World
Medical Imaging in the Global Public Health: Donation, Procurement, Installation, and Maintenance
Medical Imaging Safety in the Developing World
Information Technology in Global Health Radiology
Technologists Role in Global Health Radiology
Cultural Competency in International Health Program Collaboration
Educational Strategies and Volunteering in Global Health Radiology
Legal Nonprofit Planning
Diagnostic Imaging for Global Health: Implementation and Optimization of Radiology in the Developing World
Public Health and International Epidemiology for Radiology
Disaster Response
Infectious Disease Imaging
Interventional Procedures for Global Health Radiology
Cardiovascular Imaging in Global Health Radiology
Pediatric Imaging in Global Health Radiology
Prenatal Maternal-Fetal Imaging for Global Health Radiology
Trauma Imaging in Global Health Radiology
Women's Imaging in Global Health Radiology.

Contents:
History and current status of quality improvement in radiology
Key concepts in quality improvement
Quality improvement : definition and limitations
Quality improvement tools
Patient safety
Quality improvement in radiology
Radiology-related quality programs and organizations
Highly reliable organizations/systems in healthcare and radiology
Future of quality assurance
Evidence-based imaging
Patient-centered radiology
Professionalism and ethics
Communication
Error in radiology
Error management and reduction
Accounting in radiology
Radiology informatics
Statistical tools and quantitative reasoning
Imaging of pregnant and lactating women
Safe use of contrast media
Noninterpretive skills in ultrasound
Noninterpretive skills in magnetic resonance imaging
Optimizing radiation dose for computed tomography
Interventional radiology
Quality considerations in children
Emergency radiology
Malpractice and radiology : a hapless relationship
Leadership : a manifesto for the nonclinical education of radiologists looking to succeed in difficult times
Imaging appropriateness guidelines and clinical decision support.

Contents:
Molecular Biology of HIV/AIDS and Its Clinical Management
An Overview of Clinical Immunology of HIV/AIDS
An Overview of Clinical Microbiology of HIV/AIDS
Epidemiological Investigation of AIDS
Pathogenetic and Pathological Mechanism
Clinical Manifestations of HIV/AIDS Infection
Laboratory Test and Special Examinations
Diagnostic Imaging
AIDS Imaging and Evidence Based Medicine
Clinical Medication Against HIV/AIDS
Introduction to Assessment and Monitoring of Critical AIDS
HIV Related Effect Factors
HIV/AIDS Related Nervous System Diseases
HIV/AIDS Related Myeleterosisand Peripheral Neuropathy
HIV/AIDS Related Eye Diseases
HIV/AIDS Related Neck Diseases
HIV/AIDS Related Respiratory Diseases
HIV/AIDS Related Cardiac Diseases
HIV/AIDS Related Gastrointestinal Diseases
HIV/AIDS Related Hepatobiliary, Pancreatic and Splenic Diseases
HIV/AIDS Related Peritoneal and Retroperitoneal Disease
HIV/AIDS Related Urogenital Disease
HIV/AIDS Related Musculoskeletal Diseases
HIV/AIDS Related Pediatric Diseases
HIV/AIDS Related Skin Diseases
Functional Imaging of HIV/AIDS.

Summary: This book provides a comprehensive overview of state-of-the-art imaging in infectious and inflammatory diseases in head and neck. It starts with a brief introduction of infectious diseases in head and neck, including normal anatomy, classification, and laboratory diagnostic methods. In separate parts of eye, ear, nose, pharynx, larynx, and maxillofacial region, the common imaging techniques and imaging anatomy is firstly introduced, and then typical infectious and inflammatory diseases is presented with clinical cases. Each disease is clearly illustrated with PET and MR images and key diagnostic points. The book provides a valuable reference source for radiologists and doctors working in the area of infectious and inflammatory diseases.

Contents:
Normal Anatomy of Head and Neck
Classification of Infections and Inflammations in Head and Neck
Laboratory Tests of Infections and Inflammations in Head and Neck
Common Imaging Techniques
Imaging Anatomy of Eye and Eye Orbit
Infections and Inflammations in the Eye
Infections and Inflammations in Eye Orbit
Infections and Inflammations in the Eyelids
Common Imaging Techniques
Imaging Anatomy of Ear
Infections and Inflammations in Ear
Common Imaging Techniques
Imaging Anatomical Basis of Ear and Paranasal Sinus
Infections and Inflammations in Ear and Paranasal Sinus
Common Imaging Techniques
Imaging Anatomy of the Pharynx
Infections and Inflammations in the Pharynx
Common Imaging Techniques
Imaging Anatomy of the Larynx
Infections and Inflammations in the Larynx
Common Imaging Techniques
Imaging Anatomy of Oral Maxillofacial Region
Cellulitis of Floor of Mouth
Infections in the Parapharyngeal Space
Thyroglossal Cyst with Infection
Infections and Inflammations in Oral Maxillofacial Region
Infections and Inflammations in the Sublingual Space
Common Imaging Techniques
Imaging Anatomy of the Neck
Infections and Inflammations of Cervical Lymph Node
Infections and Inflammations of Thyroid
Abscess in the Anterior Intervertebral Space and Posterior Pharyngral Wall
Postoperative and Post-Radiotherapy Infection
Calcified Fasciitis
Necrotic Fasciitis
Common Imaging Techniques
Imaging Anatomy of Temporomandibular Joint
Infections and Inflammations of Temporomandibular Joint
Common Imaging Techniques
Imaging Anatomy of Salivary Glands
Infections and Inflammations of Salivary Glands.

Summary: This book offers a systematic coverage of diagnostic imaging in infectious and inflammatory diseases in musculoskeletal system. The first part is devoted to a general review of infectious diseases in musculoskeletal system, as well as pathogenic classification, imaging techniques, pathogenic and imaging characteristics. In the following parts, imaging interpretation of typical infectious and inflammatory diseases affecting bone, joint, and soft tissue is described. Each disease is clearly illustrated using cases combined with high-resolution CT, MRI and PET. The book provides a valuable reference source for radiologists and doctors working in the area of infectious and inflammatory diseases.

Contents:
Part 1 General Introduction to Infection and Inflammatory Diseases of Skeletal Muscles
1 Imaging Examination Techniques
2 Etiological Classification and Pathogenic Characteristics
3 Imaging Characteristics and Analysis Strategies
Part II Monographs on Infection and Inflammatory Diseases of Skeletal Muscles
4 Infectious Lesions in Bones and Joints
5 Spinal Infection
6 Bone and Joint Infection in Children
7 AIDS-related Musculoskeletal Diseases
8 Soft Tissue Infection
9 Lesions of Bones and Joints Associated with Rheumatism.

Contents:
Overview of Influenza
Etiology of Influenza
Epidemiology of Influenza
Pathomechanism of Influenza
Complications of Influenza
Radiological Modality
Laboratory Test
Influenza
Type A H1N1 Influenza
Human Infected H5N1 Avian Influenza
Human Infected H7N9 Avian Influenza
Human Infected H10N8 Avian Influenza.

Summary: This book provides richly illustrated guidance on the ever-expanding range of implants used in orthopedic surgery. The performance of these implants is assessed on radiographs, but information is not easily available and interpretation of these radiographs is difficult. Covering and illustrating implants from the neck to the foot, readers will understand the different features, what is most critical, and how to determine the overall performance. This book offers guidance for trainees, practising orthopedic surgeons, and radiologists in assessing the radiologic appearance of implants and their potential for future performance.

Contents:
General introduction to parasitic diseases
Etiology of parasitic diseases
Pathophysiology of parasitic diseases
Pathomechanism of parasitic diseases
Radiological modalities
Laboratory diagnosis
Protozoiasis
Helminthiasis
Nematodiasis
Fluke disease.

Contents:
Chapter 1. Perfect pictures, imperfect prose
Chapter 2. Expressing an imaging observation
Chapter 3. Radiology reporting best practices
Chapter 4. A guide to reporting style
Chapter 5. Mastering speech recognition
Chapter 6. Organizing the radiology report
Chapter 7. The history of radiology reporting
Chapter 8. Toward structured reporting
Chapter 9. Standard terminology for the radiology report
Chapter 10. How to think about imaging information
Chapter 11. Decision making for diagnostic imaging
Chapter 12. The future of radiology reporting
References
Index
Disclosures
Acknowlegments.

Contents:
Chapter 1. Perfect pictures, imperfect prose
Chapter 2. Expressing an imaging observation
Chapter 3. Radiology reporting best practices
Chapter 4. A guide to reporting style
Chapter 5. Mastering speech recognition
Chapter 6. Organizing the radiology report
Chapter 7. The history of radiology reporting
Chapter 8. Toward structured reporting
Chapter 9. Standard terminology for the radiology report
Chapter 10. How to think about imaging information
Chapter 11. Decision making for diagnostic imaging
Chapter 12. The future of radiology reporting
References
Index
Disclosures
Acknowlegments.

Contents:
Introduction to radiography, fluoroscopy, and tomosynthesis
Introduction to ultrasonography, CT, and MRI
Introduction to nuclear medicine and molecular imaging
Introduction to image processing, visualization, and analysis
Computers in radiology
Introduction to contrast agents
Radiation dose and safety considerations in imaging
Screening mammography
Diagnostic mammography
Breast ultrasonography (us) and breast procedures
Breast MRI
Cardiac and pericardiac imaging
Aortic imaging
Coronary arterial imaging
Pulmonary vascular imaging
CT angiography and MR angiography of the peripheral and visceral vasculature
Imaging of lung nodules and masses
Imaging of airspace lung disease
Radiography of interstitial lung disease
Imaging of mediastinal disease
Imaging of pleural disease
Tubes, lines, catheters, and other devices
Abdominal radiography
Fluoroscopy of the upper gastrointestinal tract
CT and MRI of the upper gastrointestinal tract
Fluoroscopy of the lower gastrointestinal tract
CT and MRI of the lower gastrointestinal tract
CT and MRI of the liver, gallbladder, and biliary tract
CT and MRI of the spleen
CT and MRI of the pancreas
CT and MRI of the peritoneum, omentum, and mesentery
CT and MRI of the acute abdomen and pelvis
Urography
Genitourinary tract fluoroscopy
CT and MRI of the kidney
CT and MRI of the adrenal glands
CT and MRI of the retroperitoneum
Imaging of the female pelvis
Imaging of the male pelvis
Brain imaging : anatomy, trauma, and tumors
Brain imaging : inflammatory, infectious, and vascular diseases
Advanced neurospinal imaging
Head and neck imaging, part 1
Head and neck imaging, part 2
Imaging of extremity trauma
Imaging of spinal trauma
Imaging of nontraumatic spinal disorders
Imaging of metabolic bone disease
Imaging of arthritis
Imaging of musculoskeletal infection
Imaging of musculoskeletal tumors
MRI of the shoulder
MRI of the elbow
MRI of the hand and wrist
MRI of the hip
MRI of the knee
MRI of the foot and ankle
Obstetric ultrasonography in the first trimester
Obstetric ultrasonography in the second trimester
Advanced fetal ultrasonography and therapy
Neck ultrasonography
Abdominal ultrasonography
Musculoskeletal ultrasonography
Vascular ultrasonography
Patient sedation and pain management
Equipment, terms, and techniques in interventional radiology
Inferior vena cava filters
Image-guided percutaneous needle biopsy
Advanced procedures in interventional radiology
Peripheral arterial disease diagnosis and intervention
Embolization techniques and applications
Biliary and portal venous interventions
Genitourinary and gastrointestinal interventional radiology
Neurointerventional radiology
Musculoskeletal interventional radiology
Pet of oncological disorders
Pet of nononcological disorders
Bone scintigraphy
Pulmonary scintigraphy
Thyroid, parathyroid, and salivary gland scintigraphy
Gastrointestinal and genitourinary scintigraphy
Cardiac scintigraphy
Brain scintigraphy
Radiopharmaceutical therapeutic intervention
Pediatric thoracic radiology
Pediatric cardiovascular radiology
Pediatric gastrointestinal radiology
Pediatric genitourinary radiology
Pediatric neuroradiology
Pediatric musculoskeletal radiology
Imaging of child abuse
Training pathways in diagnostic imaging
Medicolegal issues in diagnostic imaging
Radiology and other imaging-related organizations.

Summary: This atlas explores the latest advances in radionuclide imaging in the field of inflammatory diseases and infections, which now typically includes multimodality fusion imaging (e.g. in SPECT/CT and in PET/CT). In addition to describing the pathophysiologic and molecular mechanisms on which the radionuclide imaging of infection/inflammation is based, the clinical relevance and impact of such procedures are demonstrated in a collection of richly illustrated teaching cases, which describe the most commonly observed scintigraphic patterns, as well as anatomic variants and technical pitfalls. Special emphasis is placed on using tomographic multimodality imaging to increase both the sensitivity and specificity of radionuclide imaging. The aim of the second edition of this book is to update the first (published in 2013) by reflecting the changes in this rapidly evolving field. Particular attention is paid to the latest advances in the radionuclide imaging of infection and inflammation, including the expanding role of hybrid imaging with [18F]FDG PET/CT SPECT/CT, without neglecting new radiotracers proposed for the imaging of infection/inflammation. Written by respected experts in the field, the book will be an invaluable tool for residents in nuclear medicine, as well as for other specialists.

Contents:
1 Normal Findings from Different Radiopharmaceuticals and Techniques, with Variants and Pitfalls
2 Nuclear Medicine Imaging of Soft Tissue Infections
3 Nuclear Medicine Imaging of Bone and Joint Infection
4 Miscellaneous Bone and Joint conditions
5 Nuclear Medicine Imaging of Joint Prosthesis Infections
6 Nuclear Medicine Imaging of Vascular Prosthesis
7 Nonorthopedic or Cardiovascular Implantable Device Infection
8 Nuclear Medicine Imaging of Infections and Inflammation of Central Nervous System, Head and Neck Structures
9 Infective Endocarditis and Cardiovascular Implantable Electronic Device Infection
10 Nuclear Medicine Imaging of Fever of Unknown Origin
11 Nuclear Medicine Imaging of Abdominal Infections and Inflammation
12 Nuclear Medicine Imaging of Diabetic Foot
13 Nuclear Medicine Imaging of Lung Infection
14 Nuclear Medicine Imaging in Chronic Inflammatory Diseases.

Summary: This atlas, compiled by experienced specialists in the field, is designed as a ready reference on the use of parathyroid scintigraphy in patients with hyperparathyroidism, both for the localisation of parathyroid pathology and as an aid to surgery. The introductory chapters review the basic core knowledge on the subject. Eighty case reviews are then presented, covering gamma camera planar imaging, SPECT, hybrid SPECT-CT, and also PET-CT. In total, 240 illustrations are included, comprising 160 grey-scale photos depicting nuclear medicine and CT images and 80 dual-modality fusion colour photos. This compilation of illustrative clinical cases will greatly assist clinicians and imaging specialists in image interpretation in different settings. The images replicate normal conventional formats used for routine reporting and hence facilitate fast and reliable diagnosis. Each of the case reviews includes documentation of the procedure, findings, and conclusions with relevant commentary. Surgeons, nuclear medicine physicians, and radiologists will find the Radionuclide Parathyroid Imaging: Book and Atlas to be a valuable practical tool and learning aid.

Contents:
Chapter 1: Anatomy, Histology, Embryology
Chapter 2: Physiology
Chapter 3: Hyperparathyroid disorders
Chapter 4: Diagnostic Imaging: Structural Modalities
Chapter 5: Parathyroid Scintigraphy
Chapter 6: Parathyroid PET
Chapter 7: Clinical Cases: Planar, SPECT and SPECT/CT
Chapter 8: Clinical Cases: PET and PET/CT.

Summary: The main purpose of this book is to create a reference for the indications, contraindications, patient selection, treatment practice, treatment side effect management, and follow-up of radionuclide treatments. Besides standard methods such as surgery, chemotherapy, radiotherapy, and hormone therapy, newly developed biological treatments, targeted treatments, personalized treatments, external beam radiotherapy, and targeted radionuclide treatments have begun to take their place in professional practice. Nuclear medicine, in addition to its role as a tracer of cancer, also assumes the role of treating with radioactive molecules directed to the cancer it traces. These traceable next-generation radionuclide treatments, whose efficacy and reliability have been proven and where diagnosis, treatment, and follow-up are carried out together, are increasingly included in oncology practice together with the new developed radiopharmaceuticals, ensuring a high rate of damage to cancer cells while protecting the surrounding normal tissues. Molecular cancer treatment will become more effective with individualized next-generation traceable radionuclide treatments, which will be shaped by genetic studies in the future. Radionuclide treatments for many cancer types and benign diseases are presented by experienced nuclear medicine experts in the light of their own experience and case studies, while systemic treatments in common cancer types and side effect management of these treatments are summarized by medical oncologists. This book will be of interest to nuclear medicine physicians as well as oncologists.

Summary: This book provides detailed information on therapeutic radiopharmaceuticals and discusses emerging technologies which have potential for broad clinical implementation. Recent advances in molecular biology, radiopharmaceutical chemistry and radioisotope production have stimulated a new era for the use of radiopharmaceuticals for targeted radionuclide therapy (TRT). Emerging clinical trials include use of peptides and monoclonal antibodies radiolabeled with therapeutic radionuclides for cancer therapy. In addition, small molecules are used for the treatment of chronic diseases such as metastatic bone pain palliation and radiation synovectomy of inflammatory joints. In the interventional arena, therapy of primary and metastatic liver cancer and arterial restenosis following angioplasty of both the coronary and peripheral arteries are being explored. Reactor and accelerator production of therapeutic radioisotopes is also integrated into these discussions. The development and use of radiopharmaceutical targeting characteristics required for treatment of specific disease processes and how these are implemented for radiopharmaceutical design strategies are also described. Radiopharmaceuticals for Therapy will benefit audiences in nuclear medicine and radionuclide therapy and will thus prove an invaluable source of up-to-date information for students, radiopharmaceutical scientists and professionals working in the radiopharmacy and nuclear medicine specialties.

Summary: This book reviews the current clinical practice of leptomeningeal metastasis (LM) diagnosis and treatment, which is predominately by intrathecal chemotherapy and/or in combination with external beam radiotherapy. LM is a refractory lethal complication of many human malignancies when neoplastic cells grow in the meninges. The use of penetrating emissions from radionuclides has the advantages of visualizing cerebrospinal fluid (CSF) flow and ablating meninges at shallow depths and has been used to diagnose CSF flow anomalies and to treat LM. The scientific bases of using radionuclides inside human CSF and ablating LM will be discussed within the text, with results from established and completed clinical trials to explore optimal use of radionuclides to diagnose and treat LM. Many limitations of current practices of treating LM are also discussed, as well as potential avenues of overcoming these limitations. This book is an ideal guide for clinical researchers in the practice of treating leptomeningeal metastasis including radiologists, neurologists, oncologists and radiotherapists as well as their associates.

Contents:
Human Leptomeningeal Metastasis (LM)- Epidemiology and Challenges
State of Art of LM Radiographic Diagnosis Anatomic and Functional Imaging
State of Art of LM Therapies: Intrathecal and Systemic approaches
Current Practice of Radiation Therapy of LM
Radionuclides in the Diagnosis and Therapy in Neuro-Oncology
Radionuclide LM Therapy - Published Clinical Trial Findings
Intrathecal LM Dosimetry Models- Radionuclides in CSF Spaces
Human Radiation Dosimetry from Imaging- Guidance for Therapy
Radiographic Assessment for Monitoring of LM Treatment
Clinical Assessment for Monitoring of LM Treatment
Logistic and Regulatory Aspects of Locoregional Radionuclide Therapy
Radionuclides in the Management of LM Challenges and Opportunities.

Contents:
Overview of recent advances
Modes of therapy
Practical aspects of external beam therapy
Practical aspects of endocavitary beam therapy, intraoperative radiation and brachytherapy
Patient care before, during, and after radiotherapy
Target delineation, normal tissue contouring, and normal tissue constraints
Oral cavity
Nasopharynx
Oropharynx
Larync
Hypopharynx
Nasal cavity
Paranasal sinuses
Salivary glands
Thyroid
Skin
Neck node metastasis from unknown primary
Treatment of locoregional recurrence.

Contents:
Imaging, delineation and immobilization: MRI and MR-spectroscopy
PET imaging in prostate cancer
Phase contrast X-ray imaging- next generation CT imaging
Organ contouring for IMRT
General aspects of patient immobilization
Internal immobilization: From rectal balloon to hyaluronic acid
Clinical endpoints: Biochemical recurrence? a valuable endpoint?
Overall and disease-free survival ? too long to wait?
Late toxicity ? current scoring concepts
Quality of life: Assessment and Correlates
Dose escalation and new radiation techniques: Dose escalation ? an update on randomized clinical trials
IMRT for prostate cancer
IGRT- how and when
Tracking in prostate cancer
Locally advanced disease: Techniques of pelvic lymphatic irradiation
Prophylactic treatment of the pelvic lymphatics: pro
Prophylactic treatment of the pelvic lymphatics: contra
Hormonal therapy and radiation therapy
randomized and prospective trials
Treatment of clinically involved lymph nodes
Hypofractionation: Hypofractionation in prostate cancer- biological aspects
Hypofractionation: Clinical data
Simultaneous integrated boost techniques
Brachytherapy: Principals of 3D, highly conformal brachytherapy
Seed implantation
HDR brachytherapy
Adjuvant treatment and salvage treatment: Target volume definition in postoperative radiotherapy
Randomized trials for adjuvant radiotherapy
Salvage radiotherapy after radical prostatectomy
Salvage prostatectomy after radiotherapy
Use of protons and heavy ions: Proton therapy for prostate cancer: technological and clinical aspects
There is evidence for the superiority of protons or heavy ions, pro
There is evidence for the superiority of protons or heavy ions, contra. .

Summary: This book provides up-to-date information on all aspects of radiotherapy for liver cancer, from the basic science to clinical practice. While demand for radiotherapy of liver cancer has been increasing, the guidance available to clinicians has remained limited. Radiotherapy of Liver Cancer aims to address this deficit on the basis of the best available evidence. The first two sections explain the relevant basic science and present detailed information on the available technologies and techniques, including the most recent advances. The radiotherapy strategies appropriate in different patient groups are then fully described, covering the use of ablative, adjuvant, neoadjuvant, and definitive radiotherapy, radiotherapy as a bridge to liver transplantation, and palliative radiotherapy. The final section addresses a range of specific issues of concern to the clinician. Radiotherapy of Liver Cancer will be an ideal reference for clinical radiation oncologists, radiation oncology residents, oncologists, and hepatologists.

Contents:
Part 1 Basic Science in radiotherapy of liver cancer
1 Principle of Cancer Radiotherapy
2 Basic Science in radiotherapy of liver cancer - Radiobiology of liver
3 Imaging anatomy for the radiation oncologist
4 Functional assessment of liver for radiation oncologist
5 Antiviral Therapy in Liver Cancer
Part 2 Technologies and techniques in radiotherapy of liver cancer
6 Technological advances in radiotherapy
7 Basics of ablative radiotherapy - The background knowledge necessary to practicing stereotactic body radiotherapy for hepatocellular carcinoma
8 Technologies and techniques in radiotherapy of liver cancer - Image Guided Radiotherapy
9 Technologies and techniques in radiotherapy of liver cancer - Particle beam radiotherapy
10 Internal radiotherapy using radionuclides
Part 3 Radiotherapeutic strategies in liver cancer
11 Therapeutic guidelines from the perspective of radiation oncologists
12 Ablative RT for Early HCC
13 Transarterial Chemoembolization Plus External Beam Radiotherapy
14 Definitive radiotherapy for locally advanced hepatocellular carcinoma
15 Neoadjuvant RT converting to curative resection
16 Radiotherapeutic strategies in liver cancer - bridging therapy for liver transplantation
17 Palliative Radiotherapy
Part 4 Specific issues
18 Multidisciplinary team approaches for the management of hepatocellular carcinoma
19 Response evaluation after radiotherapy
20 Liver hypertrophy following radiotherapy
21 Hepatic dysfunction following radiotherapy & management
22 Lymphopenia following radiotherapy for hepatocellular carcinoma
23 Specific issues - Perspectives of RT in immuno-oncology era.

Summary: This book, in MCQ format, is a comprehensive tool that will help Nuclear Medicine and Radiology residents and attending physicians to understand concepts in nuclear medicine. Questions cover clinical applications of nuclear medicine techniques to the cardiovascular, pulmonary, endocrine, skeletal, gastrointestinal, genitourinary, and central nervous systems. In addition, topics in physics, radiopharmacy, and radiation safety are addressed. The MCQ format closely resembles that used in board examinations in nuclear medicine. Each question has four possible answers, only one of which is correct. About 60% of the questions are linked to clinical cases, with each case having four questions on average, along with one or two images. The remainder of the questions are free-standing, with or without an image. Answers are concise but are supported by references to the literature when necessary. Pearls in boxes are used to highlight the most important pieces of information. While the questions are scrambled, as in board exams, an index categorizes each question into one of the systems or topics. .

Contents:
Part I Basic science:
1. Physics of nuclear medicine
2. Radiopharmacy and Radiation Safety
Part II Clinical NM:
3. Oncology and PET/CT
4. Cardiovascular system
5. Endocrine system
6. Skeletal system
7. Pulmonary system
8. Gastrointestinal system
9. Genitourinary system
10. Central Nervous system
11. Radionuclide Therapy
12. Miscellaneous.

Contents:
Introduction and overview of rainbow program
Psychoeducation about pediatric bipolar disorder
Affect regulation skills for parents
Affect regulation skills for children
Coping skills for children
Coping and positive thinking for parents
Respectful communication and social skills for children
Promoting social skills and a balanced life for parents
Family problem solving
Creating pleasant memories and finding support
Reflecting on rainbow experience and tools learned
Final celebration.

Summary: "Jenna Arnold, director of strategic engagement for the historic 2017 Women's March, helps American white women (one of the most powerful demographics in the world-but too often passive) understand how their influence, power, and voice can better serve those most in need, and how you can take an active role in creating a better future"-- Provided by publisher.

Contents:
Silence(d)
Performance chores, perfection & privilege
White lies
Go white-savior yourself
KKK & kale smoothies
What about the boys?
"Us" vs. "them"
You, them, we
The frontline
HOLD
Our reckoning.

Summary: Medical treatments designed to help people can also be harmful or fatal. Around 2.5 million people die this way each year. So if any kind of medicine makes someone unwell, they or their doctor should report it. Those reports, from nearly every country in the world, go to the Uppsala Monitoring Centre (UMC) in Sweden. As the Centres first director, Professor Ivor Ralph Edwards transformed it from a tiny operation with limited horizons into an internationally acclaimed scientific organization at the heart of the World Health Organizations Programme for International Drug Monitoring. He was then succeeded by his wife, Dr Marie Lindquist. This is the story of how a new science developed and a passionate and dedicated pursuit of worldwide medicines safety, with an unerring focus on the welfare of patients. The pioneering work of Ralph, Marie and their collaborators on every continent protected the lives of millions of people. It may yet improve the lives of billions more.

Contents:
Chapter 01. The science, the Director and the Centre. The voyage to medicines safety. A unique vision. Made in Sweden. Going global
Chapter 02. A man changed by medicine. Just do it, Ralph. Learning for life. Forged in the City of Steel. Doctor Fixer. A new Africa. The whole world in two islands
Chapter 03. Making medicines safer. Forging ahead. A deep, dark mystery. The problems with drugs. Science and sharing. From analogue to AI. Pillars of wisdom. Doctor WHO
Chapter 04. Continuing the quest. Change at the top. A noble cause. A safer future?
Chapter 05. Present vision. Back to Africa. The view from Gothenburg.

Summary: This introduction to random walks on infinite graphs gives particular emphasis to graphs with polynomial volume growth. It offers an overview of analytic methods, starting with the connection between random walks and electrical resistance, and then proceeding to study the use of isoperimetric and Poincar inequalities. The book presents rough isometries and looks at the properties of a graph that are stable under these transformations. Applications include the 'type problem': determining whether a graph is transient or recurrent. The final chapters show how geometric properties of the graph can be used to establish heat kernel bounds, that is, bounds on the transition probabilities of the random walk, and it is proved that Gaussian bounds hold for graphs that are roughly isometric to Euclidean space. Aimed at graduate students in mathematics, the book is also useful for researchers as a reference for results that are hard to find elsewhere.

Contents:
Random walks and electrical resistance
Isoperimetric inequalities and applications
Discrete time heat kernel
Continuous time random walks
Heat kernel bounds
Potential Theory and harnack inequalities

Summary: "It is now more than ten years since the first edition of this book was published. In the intervening years, while many things have remained unchanged, there have also been many new developments over the period. This second edition refreshes the first, refining some of the sections to better explain their contents and, at the same time, replacing some examples with more current illustrations. To reflect the changes, we have created new chapters by splitting and then expanding old chapters. Thus, we now include full chapters on data and safety monitoring including interim analyses of accumulating data, cluster designs, repeated measures, and non-inferiority designs as there has been a rapid increase in the use of such trial designs along with some methodological developments and improvements in statistical software available for analysis. In addition, we have included entirely new chapters on stepped wedge designs, genomic targets and, feasibility and pilot studies. The chapter on stepped wedge designs reflects the growing importance of such complex intervention designs while that on genomic targets highlights the research focus directed towards more individualised medicine. In contrast the new chapter concerned with feasibility and pilot studies brings us back to the early planning stages of the clinical trial which is planned. The chapter is included as there is increasing recognition that perhaps a more structured approach is required at the planning stage of any proposed trial. The intention is to help avoid the conduct of clinical trials which fail due to the basic assumptions made at the planning stage being inappropriate. This edition is divided into three sections: I Basic Considerations, II Adaptions of the Basic Design, and III Further Topics. As the title suggests, the first section is intended to cover topics that are relevant to all randomised trials of whatever design and complexity. Thus, it may be the key section for those who are new to clinical trials and an aide-memoire for those more experienced in this area. For this purpose, it concentrates on the parallel two-group controlled trial with a single outcome measure where patients are randomised individually to one of the two interventions concerned. The second section expands on the individually randomised design in several ways by considering paired designs, repeated assessments of the (same) outcome measure over time, more than two interventions, and non-inferiority trials. It also includes cluster trials, and stepped wedge designs in which groups rather than individuals are randomised to the interventions concerned. The final section deals with genomic targets, feasibility and pilot studies, and a final chapter on miscellaneous topics including adaptive designs, large simple trials and very small trials with new additions describing alpha spending functions and the predictive probability test for use in interim analyses"-- Provided by publisher

Contents:
Introduction
Design Features
The Trial Protocol
Measurement and Data Capture
Randomisation
Trial Initiation
Trial Conduct and Completion
Basics for Analysis
Trial Size
Data and Safety Monitoring
Reporting
More than Two Interventions
Paired and Matched Designs
Repeated Measures Design
Non-Inferiority and Equivalence Trials
Cluster Designs
Stepped Wedge Designs
Genomic Targets
Feasibility and Pilot Studies
Further Topics.

Summary: "Rang and Dale's Pharmacology is internationally acknowledged as the core textbook for students of pharmacology, and has provided accessible, up-to-date information on drugs and their mechanism of action for more than 30 years. Now in its tenth edition, it has been updated to include important new drugs such as gene therapies, personalised medicines and the new wave of RNA drugs. However it has not lost any of the elements that have contributed to its popularity, such as color coding and illustrations, making it reader-friendly while comprehensively covering the depth of detail required. This essential book is recommended as the first-choice undergraduate text for science and medical students and junior doctors and will also be useful for students in other professional disciplines such as pharmacy, veterinary medicine and nursing"-- publisher's description.

Contents:
General principles
Chemical mediators
Drugs affecting major organ systems
Nervous system
Drugs used for the treatment of infections and cancer
Special topics.

Contents:
Children are not just small adults
The physis and skeletal injury
Orthopedic literacy : fracture description and resource utilization
Emergency fracture reduction
Casts for children's fractures
Clavicle
Shoulder and humeral shaft
Elbow : distal humerus
Elbow : proximal radius and ulna
Radius and ulna
Hand and wrist
Pelvis and hip
Femoral shaft
Knee
Tibia and fibula
Ankle
Foot
Spine
Fractures in special circumstances
Accident prevention, risk, and the evolving epidemiology of fractures.

Summary: Ranunculales is an order of flowering plants belonging to a paraphyletic group known as the basal eudicots. Medicinal plants of this order provide myriad pharmaceutically active components commonly used worldwide in ethnomedicine and traditional Chinese medicine. Interest in plant-based medicinal resources has led to discoveries of many novel compounds in various species, and to investigations on their chemodiversity, biodiversity and pharmacotherapy. Ranunculales Medicinal Plants covers this order of flowering plants comprehensively in this context; detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera, and their relevance to drug efficacy. The book carries out an exhaustive survey of the literature in order to characterize global trends in the application of flexible technologies. The interrelationship between Chinese species and between Chinese and non-Chinese species is inferred, in the text, through molecular phylogeny, based on nuclear and chloroplast DNA sequencing. The title discusses the conflict between chemotaxonomy and molecular phylogeny, in the context of drug discovery and development. It offers invaluable and holistic coverage for the study of Ranunculales as a pharmaceutical resource.

Contents:
Genomics and evolution of medicinal plants
Mining chemodiversity from biodiversity: pharmacophylogeny of Ranunculaceae medicinal plants
Mining chemodiversity from biodiversity: pharmacophylogeny of Ranunculales medicinal plants (except Ranunculaceae)
Drug metabolism and pharmacokinetic diversity of Ranunculaceae medicinal compounds
Drug metabolism and disposition diversity of Ranunculales phytometabolites
Anticancer chemodiversity of Ranunculaceae medicinal plants
Biodiversity, chemodiversity, and pharmacotherpy of Thalictrum medicinal plants
Biodiversity, chemodiversity, and pharmacotherapy of Anemone medicinal plants
Biodiversity, chemodiversity, and pharmacotherapy of Ranunculus medicinal plants
Index.

Summary: This volume provides practitioners with a practical, easy to read, well organized approach to the performance and analysis of urodynamics in order to optimize their usage clinically. Chapters are structured around specific types of patterns seen on urodynamic tracings. These urodynamic tracings are annotated and fully interpreted by the authors. Multiple examples of each type of tracing are provided with expert commentary. The expert commentary expands on the potential clinical significance of the tracing, provides a differential diagnosis, and, where appropriate, discusses its importance diagnostically, prognostically and the implications for clinical management. The text contains chapters on virtually all the relevant urodynamic findings and clinical conditions seen in practice, including lower urinary tract conditions in both adults and children, neurogenic and non-neurogenic dysfunction, and other commonly seen conditions such as lower urinary tract obstruction, vaginal prolapse, and detrusor overactivity. The material is also presented in a practical manner, with special consideration to the latest national and international guidelines. Written by authorities in the field, Rapid and Practical Interpretation of Urodynamics is a valuable resource that fills a key gap by providing a systematic method of interpretation of urodynamic tracings in an easy to understand textbook that will benefit urologic trainees and experienced urologists alike.

Contents:
Urodynamic Studies: Types and Indications
The 9 "C's" of Pressure-Flow Urodynamics
Urodynamics Equipment: Selection and Training
Physician Coding and Reimbursement for Urodynamics
Conducting the urodynamic study
Artifact recognition and solutions in urodynamics
Optimizing the study
Special Considerations in the Pediatric Patient
Special Considerations in the Neurogenic Patient
The Normal Study
Bladder Filling and Storage: "Capacity"
Bladder Filling and Storage: "Compliance"
Bladder Filling and Storage: "(Coarse) Sensation"
Bladder Filling and Storage: (Involuntary) Contractions
Bladder Filling and Storage: "Continence: Stress Incontinence"
Bladder Emptying: Contractility
Bladder Emptying: Coordination of bladder and sphincters
Bladder Emptying: Complete Emptying
Bladder Emptying: Clinical Bladder Outlet Obstruction
Test Tracings: The Final Exam
Appendix: Differential Diagnosis and Pattern Recognition: Causes of commonly encountered patterns on PFUD tracings.

Contents:
Cardiovascular
Ear, nose & throat (ENT)
Gastroenterology
Genitourinary
Infections, sepsis & infectious diseases
Mental health emergencies
Musculoskeletal
Neurology
Obstetric & gynecology
Opthalmology
Overdose & poisoning
Respiratory
Skin
The electrocardiogram.

Summary: The Rapids are a series of reference and revision pocket books that cover key facts in a simple and memorable way. Each book contains the common conditions that students and newly qualified nurses encounter on the wards, in the community, and on placements. Only the basic core relevant facts are provided to ensure that these books are perfect and concise rapid refreshers. Rapid Infection Control Nursing is an essential read for all frontline nursing staff working in hospitals or community settings. Designed for quick reference, it explores the essential principles of infection.

Contents:
The essentials
Wider aspects
A-Z of infections.

Summary: This book introduces basic ROSE techniques and resources required to set up ROSE service. It reviews the cytomorphologic features that are recognizable during ROSE, including those important for sample adequacy, specimen triage, preliminary interpretation, and potential diagnostic pitfalls. Economic and regulatory aspects are discussed as well as the pros and cons of telecytology. The book is formatted for clinical settings, simulating the ROSE process that occurs in the ultrasound room, CT room, bronchoscopy suite, and endoscopy suite. Each chapter focuses on the cytomorphologic clues and pitfalls of the entities specific to that clinical setting. Rapid On-Site Evaluation: A Practical Guide will be a valuable resource for pathologists, cytotechnologists, physicians who perform biopsies and/or ROSE evaluation, and trainees for utilizing ROSE and improving diagnostic performance of biopsies.

Summary: This book covers up-to-date evidence of Rapid on-site evaluation (ROSE) for diagnosis of rare disease and used combined with metagenomic sequencing technique in clinical scenarios. ROSE has becoming an efficient interventional diagnostics tool and important reference for lung diseases differentiation, increasing the adequacy rate, diagnostic yield and accuracy of the interventional pulmonary procedures. ROSE has its value in the field of evaluating sampling adequacy for further immunohistochemistry, microbiology studies, flow cytometry analysis, and molecular assays; DNA analysis of biopsy specimens using sequencing technique is performed to provide clue of etiology, which is an emerging pathway for clinical dilemmas. The first part of the book discusses the principals of performing ROSE procedures and reviews the basic concepts and summarized knowledge of key anatomical structures in lung. Figures of ROSE cytopathology, together with clinical data, results of metagenomic sequencing technique are presented to demonstrate how the difficulties in clinical practice could be tackled with the help of advanced techniques. Further application direction and perspective are also discussed, which provides researchers with more insights on the discipline and techniques. This book is part of the 4-volume collection ROSE in Diagnostic Interventional Pulmonology.

Contents:
Rapid on-site evaluation (ROSE) in diagnostic interventional pulmonology
Anatomic distribution and morphology of common tracheal/bronchial/pulmonary cells
Clinical data, ROSE cytopathology and metagnomic sequencing analysis in diagnosis of bacterial infection
Clinical data, ROSE cytopathology and metagnomic sequencing analysis in diagnosis of viral infection
Clinical data, ROSE cytopathology and metagnomic sequencing analysis in diagnosis of fungal infection
Clinical data, ROSE cytopathology and metagnomic sequencing analysis in diagnosis of mixed infection
Limitations and future direction.

Summary: This book provides a comprehensive overview of the "real-time accompany technique" for diagnostic interventional pulmonology, known as rapid on-site evaluation (ROSE). It also offers readers a detailed understanding of how to interpret ROSE cytological slides, which is key to the interventional procedure itself and valuable in the analysis of the infectious disease status. The first part discusses the ROSE procedure, clarifying the role of ROSE in the diagnosis of respiratory diseases, while further sections address correct work processes and the implications of ROSE, incorporating multidisciplinary perspectives on respiratory diseases, interventional pulmonology, pathology, clinical microbiology and infectious diseases. This helps practitioners, such as pulmonologists, interventional physicians, radiologists, critical care physicians, haematologists and rheumatologists, establish standardized clinical practices. The book also covers detailed clinical workups, including presentations of lesions, which are of interest to physicians from other specialties.

Summary: This book demonstrates the recent advances in rapid on-site evaluation (ROSE) for differential diagnosis of interstitial lung disease (ILD). Interstitial lung disease is a group of diffuse parenchymal lung disorders affecting the interstitium, a part of the lung's anatomic structure, causing inflammation, scarring, or excess fluid. ILDs include interstitial pneumonia, idiopathic pulmonary fibrosis, nonspecific interstitial pneumonitis, cryptogenic organizing pneumonia and sarcoidosis, which are associated with various degrees of morbidity and mortality rates. ROSE has proven its value in diagnosis with routine transbronchial lung biopsy (TBLB) procedures, especially in difficult clinical cases. The first part of the book discusses the principals of performing ROSE procedures, reviews the basic concepts and summarizes the distribution and morphology of tracheal/ bronchial/ pulmonary cells. The second part covers specific interstitial disorders, including a number of difficult and rare cases, and features iCT images and cytological illustrations. Providing readers with valuable insights, the book is an important resource for practitioners involved in the care and treatment of patients with ILD. This book is part of the 4-volume collection ROSE in Diagnostic Interventional Pulmonology.

Summary: This book offers cutting-edge evidence on using rapid on-site evaluation (ROSE) for the diagnosis of neoplastic diseases in pulmonology. ROSE has become an efficient interventional diagnostics tool and important reference for lung disease differentiation, increasing the adequacy rate, diagnostic yield and accuracy of interventional pulmonary procedures. By performing a rapid stain in the bronchoscopy suite, with evaluation by a trained physician, ROSE can be used to ensure the collection of suitable and sufficient material for ancillary studies in an era of caner-targeted therapy. ROSE holds considerable value in terms of evaluating sampling adequacy for further immunohistochemistry testing, microbiology studies, flow cytometry analysis, and molecular assays, providing a preliminary diagnosis for patient care. The first part of the book discusses the key principles for performing ROSE procedures and reviews key anatomical structures in the lung. It also covers typical cellular characteristics on the ROSE scale for pulmonary solid malignancies. The second part of the book features abundant figures and illustrations of ROSE cytopathology in common neoplastic diseases, e.g. adenocarcinoma, squamous-cell carcinoma and small cell lung cancer, while also exploring more unusual types, e.g. pneumonia-type carcinoma of the lung (PTCL), mucinous adenocarcinoma, lung mixed carcinoma, pulmonary metastases from extrapulmonary primary tumors, large cell neuroendocrine carcinoma (LCNEC), and lymphoma. This book is part of the 4-volume collection ROSE in Diagnostic Interventional Pulmonology.

Contents:
Rapid on-site evaluation (ROSE) in diagnostic interventional pulmonology
Anatomic distribution and morphology of common tracheal/bronchial/pulmonary cells
Cellular characteristics of ROSE in pulmonary solid malignancies
ROSE cytopathology cases.

Summary: This book provides an overview of the use of rapid prototyping in patients with cardiac pathology. With the exponential increase in the use of prototyping, or 3D printing technology, medical applications are becoming more widespread across specialties. Although medical centers are beginning to apply this technology for improved patient care, there is no single text to which specialists can refer for guidance about this emerging modality. The book discusses the use of rapid prototyping in medicine; model creation; image acquisition; rapid prototyping techniques; applications in congenital and structural heart disease; and development and management of a rapid prototyping service. The use of rapid prototyping for pre-procedural planning in patients with cardiac disorders such as septal defects, Tetralogy of Fallot, transcatheter aortic valve replacement, and ventricular assist devices and heart transplant significantly enhances visualization of cardiovascular anatomy. Rapid Prototyping in Cardiac Disease is a unique and valuable resource for cardiac imaging specialists, cardiothoracic surgeons, radiologists, and biomedical engineers.

Summary: The approach to total hip and total knee arthroplasty is changing around the world. There is now a strong emphasis on a more rapid recovery and on more outpatient surgery. Each step of the process is now being modified with more thorough pre-operative evaluations, streamlined surgical approaches, rapid mobilization and faster return to normal activities. These changes place new pressures on all of the health care providers in the system. This unique text - the first of its kind - is a practical guide for each member of the clinical team with updates by the leading authorities from around the country. Each chapter addresses a specific issue and will outline the important new items that need to be addressed, very similar to a handbook. Topics covered include the implementation of new payment models and outcome measurements, recommendations to streamline the pre-, peri- and post-operative protocols, the utility and application of outpatient joint replacement programs, multimodal pain management and post-acute rehabilitation strategies. There is no publication at present that addresses all of these items together in one convenient place. Rapid Recovery in Total Joint Arthroplasty is written and edited by experienced clinicians and surgeons, sharing their years of experience to create a practical, up-to-date text useful for everyday work. .

Contents:
The Changing World of Total Joint Arthroplasty
Understanding the Alternate Payment Plans
Insurance Contracting
Creating a Limited Stay Total Joint Program
Preparing Your ASC for Same Day Joints
Preparing Your Hospital for Same Day Joints
Patient Risk Assessment and Optimization
Enhanced Recovery after Surgery (ERAS): The Changing Practice
The Pre-operative Clinical Pathway
The Post-operative Clinical Pathway
Anesthesia Considerations
Efficiency in Hip Surgery
Efficiency in Knee Surgery
The Place for Innovative Technology
Multimodal Pain Management
Immediate Post-operative Rehabilitation
Achieving Milestones in Post-acute Rehabilitation
Peri-operative Patient Surveillance
Achieving Satisfaction with Patient Reported Outcome Measures
Choosing the Right Institutional Metrics
The Use of Evidence for Process Improvement.

Summary: "Careful monitoring of at-risk patients, early intervention, and timely escalation to the critical care unit from a general ward has been shown to improve patient clinical outcomes. The first text of its kind in this important area, Rapid Response Events in the Critically Ill: A Case-Based Approach to Inpatient Medical Emergencies is designed to help you recognize the fundamental signs of deterioration in patients on medical wards and ensure that transfer is made to the ICU before the development of adverse clinical outcomes. Using a highly effective teaching approach preferred by both residents and fellows, this innovative text links theory to practice with a brief review of clinical cases sourced from various academic centers"-- publisher's description.

Summary: This book is by Edward F. Goljan, MD, makes it easy for you to master all of the pathology material covered on the USMLE Steps 1 and 2. It combines an updated outline-format review of key concepts and hundreds of full-color images and margin notes, PLUS more than 400 USMLE-style online questions! Get all the practice you need to succeed on the USMLEs! New to this edition: Visualize key pathologic concepts and conditions with over 1,000 full-color images, completely reviewed and updated for this new edition.

Contents:
Diagnostic testing
Cell injury
Inflammation and repair
Immunopathology
Water, electrolyte, acid-base, and hemodynamic disorders
Genetic and developmental disorders
Environmental pathology
Nutritional disorders
Neoplasia
Vascular disorders
Heart disorders
Red blood cell disorders
White blood cell disorders
Lymphoid tissue disorders
Hemostasis disorders
Immunohematology disorders
Upper and lower respiratory disorders
Gastrointestinal disorders
Hepatobiliary and pancreatic disorders
Kidney disorders
Lower urinary tract and male reproductive disorders
Female reproductive disorders and breast disorders
Endocrine disorders
Musculoskeletal and soft tissue disorders
Skin disorders
Nervous system and special sensory disorders.

Summary: This book makes it easy for you to master all of the pathology material covered on the USMLE Steps 1 and 2. It combines an updated outline-format review of key concepts and hundreds of full-color images and margin notes, PLUS more than 400 USMLE-style online questions! Get all the practice you need to succeed on the USMLEs! Visualize key pathologic concepts and conditions with over 1,100 full-color images, completely reviewed and updated for this new edition. Also includes many new high-yield, integrated margin notes and numerous summary table for more efficient studying and understanding of disease processes. -- Publisher description

Contents:
Diagnostic testing
Cell injury
Inflammation and repair
Immunopathology
Water, electrolyte, acide, base and hemodynamic disorders
Genetic and developmental disorders
Environmental pathology
Nutritional disorders
Neoplasia
Vascular disorders
Heart disorders
Red blood cell disorders
White blood cell disorders
Lymphoid tissue disorders
Hemostasis disorders
Immunohematology disorders
Upper and lower respiratory disorders
Gastrointestinal disorders
Hepatobiliary and pancreatic disorders
Kidney disorders
Ureter, lower urinary tract and male reproductive disorders
Female reproductive disorders and breast disorders
Endocrine disorders
Musculoskeletal and soft tissue disorders
Skin disorders
Nervous system and special sensory disorders.

Contents:
[1] Diagnostic et traitement des hémorragies digestives aiguës / par Fr. Moyson et A. de Scoville avec la collaboration de S. Godart ... [et al.].

Summary: Written and edited by global leaders in this challenging field, Rare and Interstitial Lung Diseases: Clinical Cases and Real-World Discussions brings you up to date with the latest advances in complex or rare lung diseases managed on outpatient or inpatient respiratory or critical care units. Using a unique, case-based approach, a wide variety of cases are presented along with perspectives from a multidisciplinary team of experts who discuss therapeutic choices and rationales. This real-world approach allows the reader to become a virtual attending physician, simulating a realistic clinical reasoning process on the diagnosis, treatment, and follow-up of patients with rare and complex lung diseases.

Contents:
Fibrosing Interstitial Lung Diseases
Smoking-Associated Interstitial Lung Diseases
Granulomatous Lung Diseases
Connective Tissue Disease–Associated Lung Diseases
Rare and Ultra-Rare Interstitial Lung Diseases
Miscellanea.

Summary: Patients with rare diseases, affecting less than 1 in 2000 persons, frequently experience delays or errors in diagnosis, sometimes with tragic consequences. Even after the diagnosis has been established, the quality of health care delivered is often poor. This book, which is both textbook and atlas, covers the full range of rare congenital genitourinary anomalies encountered in males and females, many of which have previously been described only in sporadic case reports. In the case of the more established anomalies, variants are presented. For each anomaly, information is provided on incidence, similar cases, clinical presentation, diagnosis, possible management and outcome. Informative supporting illustrations are presented for each anomaly, and the book will serve as an excellent reference for all pediatricians, urologists and surgeons who are responsible for the care of such patients.

Contents:
MALE ANOMALIES: Genital
Penile Agenesis
Aphallia
Penile Duplication, Diphallia
Microphallus, Micropenis
Penile Torsion, Lateral Penile Curvature, Penile Deviation
Penoscrotal Transposition
Webbed Penis
Buried Penis, Hidden Penis
Agenesis Of The Scrotum, Congenital Absence Of The Scrotum
Ectopic Scrotum
Accessory Scrotum, Accessory Perineal Scrotum, Splenogonadal Fusion
Urethral
Anterior Urethral Valve
Megalourthera
Urethral Duplication
FEMALE ANOMALIES: Labial Adhesion
Ectopic Labium, Ectopic Labium Majus
Clitoral Duplication
Uterovaginal Duplication
Interlabial Masses
Urethral Prolapse, Prolapsed Ectopic Ureterocele
Hydrocolpos
Hydrometrocolpos
Sarcoma Botryoides
Rhabdomyosarcoma
Periurethral Cyst
Persistent Urogenital Sinus
Persistent Cloaca.

Summary: This book provides a broad overview of rare disease drug development. It offers unique insights from various perspectives, including third-party capital providers, caregivers, patient advocacy groups, drug development professionals, marketing and commercial experts, and patients. A unique reference, the book begins with narratives on the many challenges faced by rare disease patient and their caregivers. Subsequent chapters underscore the critical, multidimensional role of patient advocacy groups and the novel approaches to related clinical trials, investment decisions, and the optimization of rare disease registries. The book addresses various rare disease drug development processes by disciplines such as oncology, hematology, pediatrics, and gene therapy. Chapters then address the operational aspects of drug development, including approval processes, development accelerations, and market access strategies. The book concludes with reflections on the authors' case for real-world data and evidence generation in orphan medicinal drug development. Rare Disease Drug Development is an expertly written text optimized for biopharmaceutical R & D experts, commercial experts, third-party capital providers, patient advocacy groups, patients, and caregivers.

Contents:
Introduction to Rare Diseases and Market Overview
The Patient Perspective
Select Patient Narratives
The Caregiver Perspective
The Critical, Multidimensional Role of Patient Advocacy Groups in Rare Disease
A Mental Health Perspective
Investment Decisions Related to Rare Disease Drug Development
Optimizing Rare Disease Registries and Natural History Studies
Novel Approaches to Clinical Trials in Rare Diseases
Patient Benefits from Innovative Designs in Rare Diseases
Central Nervous System Rare Disease Drug Development
Oncologic Rare Disease Drug Development
Hematologic Rare Disease Drug Development
Lessons From Rare Disease and Gene Therapy Clinical Studies in Ophthalmology
Rare Diseases in the Pediatric Population
Cell and Gene Therapy in Rare Diseases
The Feasibility Assessment
The Evolving Regulatory Space and the Advent of Patient-Focused Drug Development
Operational Aspects of Rare Disease Drug Development
Accelerating Rare Disease Drug Development
Select Rare Disease Drug Approvals: Lessons Learned
A Rapid Market Access Strategy for Orphan Medicinal Products (OMPs) with Highlights Regarding the Pricing and Reimbursement Process and Barriers to Patient Use
Integrated Life Cycle Management for Rare and Orphan Products
The Case for Real-World Data and Real-World Evidence Generation in Rare and Orphan Medicinal Drug Development
Closing Remarks --

Summary: This book focuses on predictive, preventative and personalised medicine (PPPM) and how it is related to the healthcare of rare diseases. Readers will discover how advanced rare diseases healthcare provides an excellent "proof-of-principles" for the personalisation of healthcare systems on a global scale. Chapters look at national plans for rare disease, at biobanking, gene identification, rare cancers, virus gene therapy, induced pluripotency for cell therapy amongst other topics. There is a chapter dedicated to personalised medicine for hereditary deafness, and another exploring the complexity of genotype-phenotype correlations. Specific diseases such as Fabry's, Gauchers and mitochondrial cytopathies are highlighted and we look at enzyme replacement therapy in lysosomal storage diseases. This work is part of a series, produced with the involvement of the European Association for Predictive, Preventive and Personalised Medicine. The series focusses on the concept of an integrative medical approach by PPPM. This volume is dedicated to all aspects related to the prediction, prevention and personalised treatments of rare diseases, and in doing so it explores developments relevant to all medical branches. The authors cover ethical considerations, the creation of a robust platform for professional communication, synergies with patient organisations, "doctor-patient" collaboration and a new philosophy of integrative medicine by PPPM. This volume serves as a reference source for scientific and medical centres in the field and can be used both at medical curricula and graduate level in the life sciences. Those who place a special emphasis on healthcare promotion and innovations intended to combat rare diseases, save the affected lives and enhance life quality will all find this book of great value.

Contents:
National Plans on rare diseases
Biobanking for rare diseases? Impact on personalized medicine
Emerging Technologies for Gene Identification in Rare Diseases,
Personalized Medicine for Hereditary Deafness
Mitochondrial Diseases
Enzyme Replacement Therapy in Lysosomal Storage Diseases
Complexity of Genotype-Phenotype Correlations in Mendelian Disorders: Lessons from Gaucher Disease
Rare Cancers
Adeno-Associated Virus Gene Therapy and its Application to the Prevention and Personalized Treatment of Rare Diseases
Induced pluripotency for the study of disease mechanisms and cell therapy.

Contents:
Oncology
Iatrogenic
Infectious
Neurology
Genetic
Vascular
Idiopathic
Metabolic
Orthopaedic
Miscellaneous.

Summary: This second edition of the book about Rare Diseases Epidemiology aims to highlight the progress of rare diseases research and related activities since the first volume published. As with the previous book, this update provides a comprehensive list of issues and adds new authors who are leaders in their different areas of expertise related to rare diseases at national and international levels. Rare diseases and orphan drugs are challenges for patients and families but also for physicians, researchers, and policy-makers in both the public and private sectors. This book aims to help all of them to address topics like health care policies, societal issues and clinical and experimental research. Readers will discover methods and procedures to address a variety of questions like cases of undiagnosed rare diseases, patient registries and biobanks, health care and public health approach to rare diseases, orphan drugs and new therapies, cost-effectiveness analyses, prevention, clinical and epidemiology of individual and groups of related rare diseases, novel advances in study design and data analyses, national and international policies and social issues. Within each one of these general issues, advances, new challenges and opportunities to address significant health care issues are described across thirty-two chapters. Editors and all authors providing chapters include globally recognized experts in different areas of rare diseases, including epidemiology, public health, health economics and pharmacology, statistics, and basic, clinical and translational research. People engaged in policy formulation decisions on rare diseases as well as patient representatives relate their own point of view about social constraints they live under on a daily basis. Renowned research investigators, highly-skilled clinicians, and recognized patient leaders are included as contributing authors to this new book about rare diseases. In fact, two of the editors are the current President and President Elect of the International Conference on Rare Diseases and Orphan Drugs and the third one is a board member of this society. The book has been written for all stakeholders but mainly for those involved in the many issues related to rare diseases. They can discover new ways for dealing with important matters related to the prevention, diagnosis, natural history, treatments, and research of rare diseases and the development of orphan products. .

Contents:
Part I Introduction
Rare Diseases: Joining Mainstream Research and Treatment Based on Reliable Epidemiological Data
Part II Rare diseases diagnosis
Undiagnosed diseases: Italy-US collaboration and international efforts to tackle rare and common diseases lacking a diagnosis
Intellectual disability & rare disorders: A diagnostic challenge
Improved diagnosis and care for rare diseases through implementation of a precision public health framework
Part III Registries, Natural History of Rare Diseases and Biobanks
Natural history, trial readiness and gene discovery: advances in patient registries for neuromuscular disease
Facilitating Clinical Studies in Rare Diseases
Rare Diseases Biospecimens and patient registries: Interoperability for research promotion, a European example: EuroBioBank and Spain RDR-BioNER
Data Quality in Rare Diseases Registries
Preparing data at the source to foster interoperability across r are disease resources
Part IV Orphan drugs and therapies
Incentivizing orphan product development: United States Food and Drug Administration orphan incentive programs
Post-approval Studies for Rare Disease Treatments and Orphan Drugs
Evidence-Based Medicine and Rare Diseases
Health technology assessment and appraisal of therapies for rare diseases
New Therapeutic Uses for Existing Drugs
Patient empowerment and involvement in research
Part V Cost-Effectiveness and Cost-of-illness
Cost-effectiveness methods and newborn screening assessment
Cost-of-illness in rare diseases
Part VI Rare Diseases Prevention
Primary prevention of congenital anomalies: special focus on environmental chemicals and other toxicants, maternal health and health services and infectious diseases
Newborn Screening: Beyond the Spot
Part VII New Research Perspectives in RD
A Global Approach to Rare Diseases Research and Orphan Products Development: The International Rare Diseases Research Consortium (IRDiRC)
Prospects of Pluripotent and Adult Stem Cells for Rare Diseases
Personalized Medicine: What?s in for Rare Diseases?
Microphysiological systems (tissue chips) and their utility for rare disease research
Part VIII Rare Diseases Epidemiology
Epidemiology of Rare Lung Diseases: The Challenges and Opportunities to Improve Research and Knowledge
Rare neurodegenerative diseases: clinical and genetic aspects
Immunological rare diseases
Indigenous Genetics and Rare Diseases: Harmony, Diversity and Equity
Mortality Statistics and their Contribution to Improving Rare Diseases Epidemiology: the Example of Hereditary Ataxia in Europe
Congenital Anomalies: Cluster detection and investigation
Part IX Rare Diseases policies and society
The European Union Policy in the Field of Rare Diseases
The role of solidarity(-ies) in rare diseases research
Bridging the gap between health and social care for rare diseases: key issues and innovative solutions
Health systems sustainability and rare diseases
Preparing for the Future of Rare Diseases
Index.

Summary: Methods in Enzymology, Volume 650 continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this new release include Biophysical methods to study lanthanide-protein interactions, Genetically encoded sensors to study lanthanide biology, Spectrophotometric methods to determine the stability constants of lanthanide-macromolecule complexes, Lanthanide-based probes for amino acid modifications, In vitro selection and application of lanthanide-dependent DNAzymes, LRET biosensors for imaging protein interactions in living cells, Synthetic Modeling of the Structure and Function of the Lanthanide-Dependent, MDH Cofactor, EPR spectroscopy of lanthanides, Macromolecular crystallography for f-element complex characterization, and much more.

Contents:
Papillary Renal Cell Carcinoma
Renal Medullary Carcinoma
Translocation Renal Cell Carcinomas
Primitive Neuroectodermal Tumors and Other Sarcomas of the Kidney
Adult Wilms' Tumor
Urothelial Carcinoma with Variant Histology: Sarcomatoid, Plasmacytoid, and Micropapillary
Primary Sarcomas and Other Sarcomatoid Tumors of the Bladder
Neuroendocrine and Small Cell Carcinomas of the Urinary Tract
Urachal and Non-urachal Adenocarcinoma of the Bladder
Primary Urethral Carcinomas
Adenocarcinoma of the Urethra
Primary Urethral Melanoma
Neuroendocrine and Small Cell Carcinomas of the Prostate: Sentinels of Lethal Evolution
Mucinous, Signet Ring, Ductal, and Sarcomatoid Variants of Prostate Cancer
Prostate Sarcomas and Squamous Cell Carcinomas
Sex Cord Stromal Tumors of the Testis
Granulosa Cell Tumors of the Testis
Squamous Cell Carcinoma of the Penis and Scrotum
Basal Cell Carcinoma of the Male External Genitalia
Extra-mammary Paget?s Disease
Kaposi?s Sarcoma of the Penis and Scrotum
Rare Tumors of the Vulva.

Contents:
Advances in genetic testing for cancer predisposing genes
Diagnosis and management of inheritable pheochromocytomas and paragangliomas
Diagnosis and management of inheritable kidney cancer syndromes
Diagnosis and management of inheritable pancreatic cancers/melanomas
Diagnosis and management of inheritable basal cell skin cancer syndromes
Diagnosis and management of inheritable adrenal cancers
Diagnosis and management of inheritable thyroid cancers
Diagnosis and management of inheritable meningiomas/acoustic neuroma
Diagnosis and management of inheritable gastric cancer syndromes
Diagnosis and management of inheritable carcinoid syndromes
Diagnosis and management of inheritable sarcoma syndromes
Genetic testing for rare cancer syndromes: the wider issues for patients, families and health professionals.

Summary: The past decade has witnessed tremendous progress in the diagnostic and therapeutic approaches to malignant lymphoma as well as in understanding of the underlying molecular pathogenesis. Optimal treatment strategies are now based not only on accurate diagnosis but also on thorough evaluation of clinical and molecular risk factors. Even more importantly, molecular targeted approaches have been shown to be effective in the treatment of distinct lymphoma subtypes. Against this background, clinical management of especially the rare lymphomas remains a challenge for the general oncologist. This book provides a comprehensive overview of current treatment strategies in these rare lymphoma subtypes. Experts in the field from around the world describe the histomorphology in a clinically relevant manner, consider the role of risk factors in detail, and discuss the spectrum of therapeutic approaches. Special emphasis is placed on the translation of molecular science into clinical care, and a disease-specific algorithm is proposed for each entity. This book will prove an excellent resource for both experienced and inexperienced practitioners.

Summary: This book provides practitioners with a single volume that reviews the clinical and pathologic features of rarely encountered cutaneous neoplasms. The text includes an in-depth discussion of the clinical findings, as well as the histologic and immunologic features of these diseases that are rarely encountered, reported, or recognized. Additional laboratory data used to make and support the diagnoses with some therapeutic and prognostic hints are discussed for each entity. The volume is organized into general categories correlating with the cell(s) of origin. An atlas of clinical manifestations is presented for each entity that will serve as a bedside clinical reference, followed by a series of photomicrographs depicting the histologic changes. In all cases, recent updates on molecular tools helpful in attaining the diagnosis are added to the sections on histology and immunohistochemistry. Rare Malignant Skin Tumors is a valuable bedside reference for the practicing dermatopathologist, general pathologist reviewing skin biopsies, general dermatologists, cutaneous oncologists and Mohs? surgeons.

Summary: This is the first book to be devoted exclusively to rare tumors in children and adolescents. The completely revised and updated second edition reflects the significant progress that has been accomplished as a result of intensified international networking, deeper implementation of novel diagnostic tools, and the advent of molecular targeted therapies. Readers will find practical guidance on all aspects of clinical management, including diagnostic workup, multimodal therapy, follow-up, and management of adverse effects. The discussion of differential diagnosis encompasses both frequent and rare tumor types, enabling clinicians to take rare entities into account during diagnostic assessment of childhood tumors. Detailed therapeutic recommendations, developed in an international consensus process, are provided for specific rare tumors. In addition, general issues such as epidemiology, etiology, risk factors, biology and genetics, early detection, and screening are fully covered. The book is written by an international and multidisciplinary group of specialists and will be an important compendium for all pediatric oncologists who care for patients with rare tumors.

Contents:
1. Introduction: Rare Cancers: a different perspective on oncology
2. Epidemiology and etiology of rare cancers
3. National and international study groups
4. Information and ressources for patients with rare tumors
5. Rare tumors of the head and neck
6. Rare tumors of the thorax
7. Rare tumors of the gastrointestinal tract
8. Germ cell tumors and genitourinary tumors
9. Rhabdoid tumors
10. Rare tunmors of the peripheral nervous system
11. Rare tumors of the skin and subcutaneous tissue
12. Vascular tumors including Kaposi sarcoma
13. Rare mesenchymal tumors
14. Tumors of unkown primary site
15. Rare tumors as second malignancies.

Summary: This volume on Rarer Arthropathies, part of the series "Rare Diseases of the Immune System" aims to fill a gap in the literature by informing and updating clinicians on the unusual and uncommon forms of arthritis and related musculoskeletal conditions. It will be a valuable go-to resource for clinicians to support them in differential diagnosis, in particular when facing unusual presentations. Nineteen chapters written by experts have covered a wide range of these conditions, providing first rate information on topics yet lacking adequate coverage; from Palindromic Rheumatism to SAPHO Syndrome and other chronic immune-mediated conditions, while also including arthritis in leprosy, tuberculosis and chikungunya. Smaller, crisp paragraphs and apt subheadings will help the readers in easily understanding the up to date information provided in the chapters. Line diagrams, original full-color clinical photographs and informative tables also support easy assimilation of information, turning this book in a useful ready reckoner on the desks and smartphones. All specialists, including rheumatologists, orthopedic surgeons, pediatricians, physicians practicing internal medicine and rehabilitation medicine will find this volume invaluable in their daily clinical work.

Summary: "Advances in Cancer Research, volume 153 provides a timely review of the biology, biochemistry, and current approaches to therapeutically target the RAS oncoprotein, the most frequently mutated oncogene family in human cancers. 2021 saw the approval of the first direct RAS inhibitor (sotorasib) for use in treating non-small cell lung cancers harboring KRAS(G12C) mutations. The successful approval and use of this drug highlights that the once "undruggable" RAS is indeed pharmacologically tractable. This volume provides an overview of efforts to develop additional approaches to therapeutically target oncogenic RAS. In addition, the reader will find excellent reviews on the history and research efforts to understand the biochemistry and oncogenic activity of RAS in human cancers."--publisher's web page, viewed February 1, 2022.

Contents:
The Ras superfamily of small GTPases : the unlocked secrets / Luca Goitre [and three others]
A novel method for the production of fully modified K-Ras 4B / Tanmay S. Chavan [and four others]
Metabolic labeling of Ras with tritiated palmitate to monitor palmitoylation and depalmitoylation / Frederick D. Tsai [and three others]
Ubiquitination of Rac1 by inhibitors of apoptosis (IAPs) / Tripat Kaur Oberoi-Khanuja and Krishnaraj Rajalingam
Ras GTPases are both regulators and effectors of redox agents / Elisa Ferro [and four others]
Biophysical and proteomic characterization strategies for cysteine modifications in Ras GTPases / G. Aaron Hobbs, Harsha P. Gunawardena, and Sharon L. Campbell
Use of the yeast two-hybrid technology to isolate molecular interactions of Ras GTPases / Elisa Ferro, Eva Baldini, and Lorenza Trabalzini
Screening for MAPK modulators using an In-Cell Western assay / Simon Schnaiter [and seven others]
Behavioral methods for the study of the Ras-ERK pathway in memory formation and consolidation : passive avoidance and novel object recognition tests / Raffaele d'Isa, Riccardo Brambilla, and Stefania Fasano
Functional phosphoproteomics of oncogenic KRAS signaling / Putty-Reddy Sudhir and Jeou-Yuan Chen
Pull-down assay for analysis of integrin-mediated activation of Rap proteins in adherent platelets / Gianni Francesco Guidetti and Mauro Torti
Combined pulldown and time-lapse microscopy studies for determining the role of Rap1 in the crosstalk between integrins and cadherins / Luca Goitre and Saverio Francesco Retta
Fluorescence microscopy study of Rap1 subcellular localization / Luca Goitre, Valentina Cutano, and Saverio Francesco Retta
An in vitro system to evaluate the scaffold function of the RalA effector protein RalBP1 / David F. Kashatus
Analysis of the Rit subfamily GTPase-mediated signaling and neuronal differentiation and survival / Geng-Xian Shi and Catherine N. Kaminski
Immunofluorescence methods in studies of the GTPase Ran and its effectors in interphase and in mitotic cells / Giulia Guarguaglini, Valeria de Turris, and Patrizia Lavia
High-resolution scanning electron microscopy for the imaging of nuclear pore complexes and Ran-mediated transport / Lihi Shaulov, Boris Fichtman, and Amnon Harel
Effector recruitment method to study spatially regulated activation of Ras and Rho GTPases / Lauren P. Huff, Molly J. DeCristo, and Adrienne D. Cox
Real-time visualization and quantification of native Ras activation in single living cells / Christoph Biskup and Ignacio Rubio
Nanoclustering and heterogeneous membrane diffusion of Ras studied by FRAP and RICS analysis / Camilo Guzmâan, Maja éSolman, and Daniel Abankwa
Analyzing the roles of Rho GTPases in cancer cell migration with a live cell imaging 3D-morphology-based assay / Audrey Colomba and Anne J. Ridley
Analysis of Rho GTPase-induced localization of nanoscale adhesions using fluorescence nanoscopy / Annica K.B. Gad [and three others]
Yeast as a model for Ras signalling / Renata Tisi, Fiorella Belotti, and Enzo Martegani
Methods to study the Ras2 protein activation state and the subcellular localization of Ras-GTP in Saccharomyces cerevisiae / Sonia Colombo and Enzo Martegani
Ras proteins signaling in the early metazoan Dictyostelium discoideum / Enrico Bracco and Barbara Pergolizzi.

Summary: Written specifically for non-infectious disease specialists in both inpatient and outpatient settings, A Rational Approach to Clinical Infectious Diseases provides concise, practical guidance that mimics the decision-making process and reasoning employed by an ID physician. Using clear, understandable language, Dr. Zelalem Temesgen and his esteemed colleagues at the Mayo Clinic present the art and the context of infectious diseases together with the science, helping non-specialists apply a rational approach to the diagnosis and treatment of infectious conditions.

Contents:
General approach to infectious diseases evaluation / Omar M. Abu Saleh, Zelalem Temesgen
Interacting with the clinical microbiology laboratory / Elitza S. Theel, Audrey N. Schuetz
A primer on microbiology / Brian Schwartz, Erin M. Bonura
General principles of antimicrobial therapy Jaap ten Oever, Inge C. Gyssens
A primer on antimicrobials / Richard R. Watkins
Fever of unknown origin / Mary Jo Kasten
Fever and rash / Diana Vilar-Compte, Patricia Cornejo-Juarez, Elizabeth Salazar Rojas
Ear, nose, throat, and neck infections / John C. O'Horo, Kelly Cawcutt
Lower respiratory tract infections / John C. O'Horo, Kelly Cawcutt
Select gastrointestinal and hepatobiliary infections / Robert Orenstein
Urinary tract infections / Dimitri M. Drekonia
Skin and soft tissue infections / Silvano Esposito, Pasquale Pagliano, Anna Maria Spera
Bone and joint infections / Talha Riaz, Aaron J. Tande
Diagnostic approach to a patient with suspected central nervous system infection / Adarsh Bhimraj
Vector-borne infections / Raj Palraj
Sepsis / Micah Beachy, Kelly Cawcutt
Sexually transmitted infections / Arlene C. Sena, Srilatha Edupuganti
HIV infection / Jessica S. Tischendorf, James M. Sosman
Bacteremia / Aditya Shah, Daniel C. DeSimone.

Contents:
Introduction (McCue)
Elderly suicide through history (McCue)
Acceptability of elderly suicide across cultures
Baby boomers and the wish to control life and death
Can suicide in the elderly be rational? (Lawrence Nelson)
Clinical criteria for rational suicide in the elderly
Who are the elderly who want to end their lives?
Existential issues in late-life rational suicide
Psychological issues in late-life rational suicide (Elissa Kolva)
Psychodynamic issues in late-life rational suicide (Balasubramaniam)
Terminal mental illness and the wish to die (Barbara Sommer)
The impact of spirituality on the rationality of suicide
The impact of psychotherapy on the rationality of suicide (Elissa Kolva)
The impact of psychopharmacology on the rationality of suicide (Balasubramaniam)
Commentary.

Contents:
Abt. 2. Knochen, Bänder
Abt. 3. Muskeln, Gefässe
Abt. 4. Eingeweide
Abt. 5/6. Nervensystem, Sinnesorgane : nebst Anhang, Grundzüge der Oberflächen- und Projektions-Anatomie.

Contents:
Normal tissue tolerance to reirradiation
Fractionation concepts
Hyperthermia and reirradiation
Therapeutic ratio of reirradiation with cytotoxic drugs and other response-modifying agents
Reduced normal tissue doses through advanced technology
Proton beam reirradiation
Brain tumours
Eye tumors
Re-irradiation in head and neck cancer
Nasopharyngeal carcinoma
Lung cancer
Re-irradiation for esophageal cancer
Re-irradiation for locally recurrent breast cancer
Prostate cancer
Rectal cancer
Gynecological malignancies
Reirradiation for soft tissue sarcomas
Re-irridation for recurrent skin cancer
Leukemia and lymphoma
Bone metastases
Brain metastases
Index.

Summary: "Tell the doctor where it hurts." It sounds simple enough, unless the problem affects the very organ that produces awareness and generates speech. What is it like to try to heal the body when the mind is under attack? In this book, Dr. Allan Ropper and Brian Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound: A figure skater whose body has become a ticking time-bomb. A salesman who drives around and around a traffic rotary, unable to get off. A college quarterback who can't stop calling the same play. A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive. A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth living. How does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance"-- Provided by publisher.

Summary: Reactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term 'oxidative stress' is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com

Contents:
Part I: ROS Revisited: Changing the Focus from Oxidative Stress and Redox Biology to Redox Medicine
Demystifying oxidative stress
Oxidants in Physiological Processes
Network Medicine-Based Unbiased Disease Modules for Drug and Diagnostic Target Identification in ROSopathies
Part II Targeting antioxidant responses
Development of Telintra as an Inhibitor of Glutathione S-Transferase P
Perspectives on the Clinical Development of NRF2-Targeting Drugs
Part III: Inhibiting ROS formation and toxification
NOX Inhibitors: From Bench to Naxibs to Bedside
Nitric Oxide Synthase Inhibitors into the Clinic at Last
Xanthine Oxidoreductase Inhibitors
Monoamine Oxidase Inhibitors: From Classic to New Clinical Approaches
Inhibition of Myeloperoxidase
Part IV: Stimulating/substituting ROS
Effects of Mammalian Thioredoxin Reductase Inhibitors
Cardiovascular Therapeutic Potential of the Redox Siblings, Nitric Oxide (NO" and Nitroxyl (HNO), in the Setting of Reactive Oxygen Species Dysregulation
Tetrahydrobiopterin and Nitric Oxide Synthase Recouplers
Part V: Repairing ROS damage
Soluble Guanylate Cyclase Stimulators and Activators
Peter Sander
Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation.

Contents:
1. Introduction to scientific reading and writing and to technical modalities of augmentation
2. Ecrilecture and the constructino of knowledge within professional communities
3. "Critical spaces": a study of the necessary conditions for scholarly and multimedia reading
4. "Annotate the world, and improve humanity": material imageries in a web annotation program
5. Construction of ecrilecture standards for collaborative trsncription of digitized heritage
6. The challenge of platform interoperability in constructing augmented knowledge in the humanities and social sciences
7. The XML portal for the symogih.org Project
8.Issues of "hypermediating journals" for scientific publishing.

Summary: "Reading EEGs: A Practical Approach focuses on pattern recognition and pattern comparison. The concepts of pattern recognition are developed in a logical fashion based on appearance rather than disease process. The book teaches waveform recognition so that the reader can generate a differential diagnosis based on that recognition. This book also incorporates a question-and-answer format that is effective for students at multiple levels of training"-- Provided by publisher.

Contents:
Basic Neuroscience of EEG / L. John Greenfield, Jr.
Electronics of EEG / L. John Greenfield, Jr. and James D. Geyer
Recording the EEG / L. John Greenfield, Jr.
Approaching the EEG: An Introduction to Visual Analysis / L. John Greenfield, Jr
Artifacts and Noise / L. John Greenfield, Jr
The Normal Adult EEG / L. John Greenfield, Jr
Normal EEG in the Newborn, Infant, and Adolescent / Paul R. Carney, James D. Geyer and L. John Greenfield, Jr.
Focal and General Rhythm Abnormalities / James D. Geyer and Paul R. Carney
Epileptiform Activity, Seizures and Epilepsy Syndromes / Linda M. Selwa
Pathophysiology of Epileptiform Activity / L. John Greenfield and Sanghun Lee
Status Epilepticus EEG Patterns in Adults / Emily Johnson and Peter W. Kaplan
Neonatal and Pediatric Epilepsy Syndromes / James D. Geyer, Paul R. Carney and L. John Greenfield, Jr.
Video EEG Monitoring and Epilepsy Surgery / Vibhangini S. Wasade and Jules E.C. Constantinou
Seizure Semiology: Signs of the Seizure / James D. Geyer, Paul R. Carney and L. John Greenfield, Jr.
Subdural Electrode Corticography / William O. Tatum, Sanjeet Grewal
Stereotactic Electroencephalography in Epilepsy / Sanjeet Grewal, Karim ReFaey, William O. Tatum
EEG in Specific Disease States / James D. Geyer, Paul R. Carney and Erasmo A. Passaro
Introduction to Sleep and Polysomnography / James D. Geyer and Paul R. Carney
Evoked Potentials and Intraoperative Monitoring / David B MacDonald and Charles Dong
New Frontiers in EEG: High and Low Frequencies, High Density EEG, Digital Analysis and Magnetoencephalography / David Burdette and Andrew Zillgitt
Genetics of EEG and Epilepsy / James D. Geyer, Paul R. Carney and L. John Greenfield, Jr.
Seizure Detection and Advanced Monitoring Techniques / Nicholas Fisher, Sachin Talathi, Alex Cadotte, Stephen Myers, William Ditto, James
D. Geyer, Emery E. Geyer, and Paul R. Carney
Non-Epileptic Events / Nicholas J. Beimer and Linda M. Selwa
EEG Inter-rater Reliability / James D. Geyer and Paul R. Carney.

Summary: "This funny, candid memoir about the author's intern year at a New York hospital provides a scorchingly frank look at how doctors are made, taking readers into the critical care unit to see one burgeoning physician's journey from ineptitude to competence. After his professional baseball career failed to launch, Matt McCarthy went to Harvard Medical School and on to a coveted residency slot in New York. But when he almost lost a patient on his first day after making what he believed to be a terrible error, he found himself facing the harsh reality of a new doctor's life--one in which even overachievers find themselves humbled, and in which med school training has little to offer in navigating the emotional rollercoaster of dealing with actual patients. Luckily for McCarthy, his second-year-resident adviser (whom he calls "Baio", owing to a resemblance to a Charles in Charge-era Scott Baio) was an offbeat genius, with a knack for breaking down the complicated process of treating patients. But neither doctor could offer much help to a patient named Barney, who had been living in the hospital while waiting for a new heart, and whom McCarthy slowly befriended over the course of the year in ways that changed his perception of what it means to be a physician. Mixing the tense drama of ER with the screwball humor of Scrubs, McCarthy offers a window on to hospital life that dispenses with sanctimony and self-seriousness while emphasizing the black-comic paradox of becoming a doctor: How do you learn how to save lives in a job where there is no practice? This "One L for doctors" will inspire and entertain physicians and patients alike"-- Provided by publisher.

Summary: "A novel of rare emotional power that excavates the social intricacies of a late-summer weekend -- and a lifetime of buried pain. Almost everything about Wallace, an introverted African-American transplant from Alabama, is at odds with the lakeside Midwestern university town where he is working toward a biochem degree. For reasons of self-preservation, Wallace has enforced a wary distance even within his own circle of friends -- some dating each other, some dating women, some feigning straightness. But a series of confrontations with colleagues, and an unexpected encounter with a young straight man, conspire to fracture his defenses, while revealing hidden currents of resentment and desire that threaten the equilibrium of their community"-- Provided by publisher.

Summary: This book describes the use of real-time three-dimensional transesophageal echocardiography (3D TEE) in percutaneous interventional procedures, underlining its growing role and acceptance among interventional cardiologists, while also considering technique-related weaknesses.

Contents:
1. Technological issues
2. Closure of patent foramen ovalis and atrial septal defect
3. Catheter-based repair of mitral valve insufficiency
4. Percutaneous balloon mitral commissurotomy
5. Transcatheter aortic valve implantation
6. Percutaneous closure of the left atrial appendage
7. Closure of post-AMI ventricular septal defect
8. Percutaneous closure of paravalvular leaks
9. The role of 3D TEE in ablation procedures
10. Miscellaneous procedures.

Contents:
Intro
Real-World Applications in Cognitive Neuroscience
Copyright
Contributors
Contents
Preface
Chapter 1: Science of perception, decision making and fatigue in the maritime industry
1. Introduction
2. Perception at sea
2.1. Attention
2.2. Working in night lighting conditions
2.3. Lighting
2.4. What and where
2.5. Visual size and distance
3. Decision making at sea
3.1. Communication and culture
3.2. Trusting our guts
3.3. Group decisions
3.4. Fatigue
4. Conclusion: Using neuroscience to improve safety at sea
Acknowledgments 2.3.1. Menstrual cycle mapping
2.4. Physiological training data
2.4.1. Physiological data analysis
2.5. Decision making tests
2.5.1. Cambridge gambling task (CGT)
2.5.2. CGT analysis
2.6. Qualitative methodology
2.6.1. Semi-structured interviews
2.6.2. Interview analysis
3. Results
3.1. Physiological data results
3.1.1. Whole group
3.1.2. Naturally menstruating group & oral contraceptive user groups
3.1.3. Individual participant analysis
3.2. Decision making results
3.2.1. Impulsivity
3.2.2. Risk taking
3.2.3. Response time
3.2.4. Error rates 3.3. Semi-structured interviews results
3.4. Results summary
4. Discussion
4.1. Physiological performance
4.1.1. Cognitive changes
4.1.2. Use of oral contraceptives as a management strategy
4.1.3. Recommendations
4.1.4. Competition and the menstrual cycle
4.1.5. Psychological management
4.1.6. Oral contraceptive use
4.1.7. Individual monitoring
4.2. Some limitations
5. Conclusion
References
Chapter 4: Assessing decision-making in elite academy footballers using real-world video clips
1. Introduction
2. Methods and materials
2.1. Participants 2.2. Experimental design
2.3. Statistical analysis
3. Results
3.1. Correlation between performance on the task and coaches opinion in all participants
3.2. Correlation between performance on the task and coaches opinion in the U16 group
3.3. Correlation between performance on the task and coaches opinion in the U18 group
3.4. Correlation between performance on the task and coaches opinion in the U23 group
4. Discussion
References
Chapter 5: Assessing decision making using 2D animations in elite academy footballers
1. Introduction
2. Method and materials

Contents:
Human motivation: "In general why do people do what they do?"
Human motivation: "Specifically why do people do what they do?"
The counseling environment: "How do I set the stage for self-evaluation?"
What is the WDEP system?
Career concerns
Cross-cultural applications
Dealing with loss, posttraumatic stress, self-injury, conflict, and anger
Reality threapy FAQs
Conclusion.

Summary: "Realizing the Promise of Precision Medicine: The Role of Patient Data, Mobile Technology, and Consumer Engagement explains the potential of personalized medicine and the value of those approaches in making that potential a reality. The book helps transform one-size-fits-all healthcare into a system that focuses on individual needs and the unique needs of each family member, discussing topics such as U.S. sponsored precision medicine initiative, genomics, the role of electronic health records and mobile medicine, patient engagement and empowerment, health information exchange and patient data protection. In addition, the book discusses the barriers and limitations of precision medicine and how to overcome them. Readers will find valuable insights into how big data, patient engagement, mobile technology, and genomics help individualize medical care and offer a pathway to help detect many undiscovered causes of diseases.Provides drawings and flow charts to help readers visualize the breadth and depth of precision medicine includes sidebars with more details on specific topics for a complementary, deeper understanding of text. Uses case studies to turn abstract concepts into flesh and blood examples of how personalized medicine benefits patients"-- Provided by publisher.

Contents:
Population Medicine Versus Personalized Medicine
Precision Medicine Initiatives and Programs
The Role of Genomics
Small Data, Big Data, and Data Analytics
How Mobile Technology and EHRs Can Personalize Healthcare
i2b2, SHRINE, Clinical Query, and Other Research Tools
Barriers and Limitations
Interoperability and Personalized Patient Care
Privacy and Security
Patient and Consumer Engagement.

Summary: Reasoning: The Neuroscience of How We Think is a comprehensive guide to the core topics related to a thorough understanding of reasoning. It presents the current knowledge of the subject in a unified, complete manner, ranging from animal studies, to applied situations, and is the only book available that presents a sustained focus on the neurobiological processes behind reasoning throughout all chapters, while also synthesizing research from animal behavior, cognitive psychology, development, and philosophy for a truly multidisciplinary approach. The book considers historical perspectives, state-of-the-art research methods, and future directions in emerging technology and cognitive enhancement. Written by an expert in the field, this book provides a coherent and structured narrative appropriate for students in need of an introduction to the topic of reasoning as well as researchers seeking well-rounded foundational content. It is essential reading for neuroscientists, cognitive scientists, neuropsychologists and others interested in the neural mechanisms behind thinking, reasoning and higher cognition.

Contents:
Introduction to Reasoning
The History of Reasoning Research
The Neuroscience of Reasoning
Comparative Reasoning: A Cross-Species Perspective
Reasoning Origins: Human Development During Childhood
Reasoning Over the Lifespan
Disorders of Reasoning
Reasoning About Contingencies, Correlations, and Causes
Deduction and Induction
Analogical Reasoning
Decision Making and Abdutive Reasoning
Social Cognition: Reasoning With Others
Future Directions in Reasoning: Emerging Technology and Cognitive Enhancement.

Summary: This book argues that in order to be truly effective, public health must embrace a group of reasoning strategies that have traditionally been characterized as informal fallacies. It will be demonstrated that these strategies can facilitate judgements about complex public health issues in contexts of uncertainty. The book explains how scientists and lay people routinely resort to the use of these strategies during consideration of public health problems. Although these strategies are not deductively valid, they are nevertheless rationally warranted procedures. Public health professionals must have a sound understanding of these cognitive strategies in order to engage the public and achieve their public health goals. The book draws upon public health issues as wide ranging as infectious diseases, food safety and the potential impact on human health of new technologies. It examines reasoning in the context of these issues within a large-scale, questionnaire-based survey of nearly 900 members of the public in the UK. In addition, several philosophical themes run throughout the book, including the nature of uncertainty, scientific knowledge and inquiry. The complexity of many public health problems demands an approach to reasoning that cannot be accommodated satisfactorily within a general thinking skills framework. This book shows that by developing an awareness of these reasoning strategies, scientists and members of the public can have a more productive engagement with public health problems.

Contents:
Chapter One: The Challenge for Public Health
Chapter Two: Philosophy and Public Health
Chapter Three: Argument from Ignorance
Chapter Four: Argument from Authority
Chapter Five: Argument from Analogy
Chapter Six: Circular Argument
Chapter Seven: Fallacies in Public Health
Chapter Eight: Theory of Public Health Reasoning
Bibliography
Index.

Summary: White biotechnology, or industrial biotechnology as it is also known, refers to the use of living cells and/or their enzymes to create industrial products that are more easily degradable, require less energy, create less waste during production and sometimes perform better than products created using traditional chemical processes. Over the last decade considerable progress has been made in white biotechnology research, and further major scientific and technological breakthroughs are expected in the future. Fungi are ubiquitous in nature and have been sorted out from different habitats, including extreme environments (high temperature, low temperature, salinity and pH), and may be associated with plants (epiphytic, endophytic and rhizospheric). The fungal strains are beneficial as well as harmful for human beings. The beneficial fungal strains may play important roles in the agricultural, industrial, and medical sectors. The fungal strains and their products (enzymes, bioactive compounds, and secondary metabolites) are very useful for industry (e.g., the discovery of penicillin from Penicillium chrysogenum). This discovery was a milestone in the development of white biotechnology as the industrial production of penicillin and antibiotics using fungi moved industrial biotechnology into the modern era, transforming it into a global industrial technology. Since then, white biotechnology has steadily developed and now plays a key role in several industrial sectors, providing both high value nutraceutical and pharmaceutical products. The fungal strains and bioactive compounds also play an important role in environmental cleaning. This volume covers the latest developments and research in white biotechnology with a focus on diversity and enzymes.

Contents:
Preface
Biodiversity of Fungi from Extreme Habitats and Its Industrial Applications
Rhizospheric Fungi Isolated from Different Plants and Potential Applications in Diverse Sectors
Endophytic Fungi from Different Niches with Potential Industrial Importance
Marine Fungal White Biotechnology
Aspergillus Biodiversity, Ecological Significance, and Industrial Applications
Fusarium Biodiversity, Ecological Significance, and Industrial Applications
Penicillium Biodiversity, Ecological Significance, and Industrial Applications
Trichoderma Biodiversity, Ecological Significance, and Industrial Applications
Thermostable Enzymes from Fungi Isolated from Hot Springs and Its Applications
Cold Active Enzymes from Psychrophilic Fungi and Its Applications
Industrially Important Enzymes from White-Rot Fungi or Filamentous Fungi
Fungal Enzymes for the Textile Industry
Fungal Laccase
Fermentation Process for Production of Fungal Cellulases
Fungal Lipases
Fungal Community and Eco-Friendly Bioresources for Novel Secondary Metabolites
Agriculturally Important Fungi
Fungal White Biotechnology in Biosurfactants
Synthetic Biology and a Novel Approach for Pharmaceutically Important Compounds
Global Scenario of Fungal White Biotechnology
Appendixes
Index

Summary: White biotechnology is industrial biotechnology dealing with various biotech products through applications of microbes. The main application of white biotechnology is commercial production of various useful organic substances, such as acetic acid, citric acid, acetone, glycerine, etc., and antibiotics like penicillin, streptomycin, mitomycin, etc., and value added product through the use of microorganisms especially fungi and bacteria. The value-added products included bioactive compounds, secondary metabolites, pigments and industrially important enzymes for potential applications in agriculture, pharmaceuticals, medicine and allied sectors for human welfare. In the 21st century, techniques were developed to harness fungi to protect human health (through antibiotics, antimicrobial, immunosuppressive agents, value-added products etc.), which led to industrial scale production of enzymes, alkaloids, detergents, acids, biosurfactants. The first large-scale industrial applications of modern biotechnology have been made in the areas of food and animal feed production (agricultural/green biotechnology) and pharmaceuticals (medical/red biotechnology). In contrast, the production of bio-active compounds through fermentation or enzymatic conversion is known industrial or white biotechnology. The beneficial fungal strains may play important role in agriculture, industry and the medical sectors. The beneficial fungi play a significance role in plant growth promotion, and soil fertility using both, direct (solubilization of phosphorus, potassium and zinc; production of indole acetic acid, gibberellic acid, cytokinin and siderophores) and indirect (production of hydrolytic enzymes, siderophores, ammonia, hydrogen cyanides and antibiotics) mechanisms of plant growth promotion for sustainable agriculture. The fungal strains and their products (enzymes, bio-active compounds and secondary metabolites) are very useful for industry. The discovery of antibiotics is a milestone in the development of white biotechnology. Since then, white biotechnology has steadily developed and now plays a key role in several industrial sectors, providing both high valued nutraceuticals and pharmaceutical products. The fungal strains and bio-active compounds also play important role in the environmental cleaning. This volume covers the latest research developments related to value-added products in white biotechnology through fungi.

Contents:
Foreword
Preface
Agriculturally and Industrially Important Fungi: Current Developments and Potential Biotechnological Applications
Fungal Phytases: Biotechnological Applications in Food and Feed Industries
Fungal Probiotics: Opportunity, Challenge and Prospects
Fungal White Biotechnology Applications for Food Security: Opportunities and Challenges
Volatile Organic Compounds from Endophytic Fungi
Natural Value-Added Compounds form Fungal Communities
Natural Product Synthesis by Fungi: Recent Trends and Future Prospect
Fungal Derived Natural Product: Synthesis, Function, and Applications
Fungal Community for Novel Secondary Metabolites
Industrially Important Pigments from Different Groups of Fungi
Bioactive Compounds of Endophytic Fungi associated with Medicinal Plants
Extracellular Carbohydrate-Active Enzymes of Trichoderma and their Role in the Bioconversion of Nonedible Biomass to Biofuel
Fungal Biofuels: Innovative Approaches
Lignocellulosic biomass to fungal Single Cell Oils: A radical bioconversion towards establishing a prospective resource
Recent Advancement and the Way Forward for Cordyceps
Synthetic Biology: A Novel Approach for Pharmaceutically Important Compounds
Index.-

Summary: Over the last decade considerable progress has been made in white biotechnology research and further major scientific and technological breakthroughs are expected in the future. The first large-scale industrial applications of modern biotechnology have been in the areas of food and animal feed production (agricultural/green biotechnology) and in pharmaceuticals (medical/red biotechnology). In contrast, the productions of bio-active compounds through fermentation or enzymatic conversion are known as industrial or white biotchnology. The fungi are ubiquitous in nature and have been sorted out from different habitats, including extreme environments (high temperature, low temperature salinity and pH);and associated with plants (Epiphytic, Endophytic and Rhizospheric). The fungal strains are beneficial as well as harmful for human beings. The beneficial fungal strains may play important roles in the agricultural, industrial, and medical sectors. The fungal strains and its product (enzymes, bioactive compounds, and secondary metabolites) are very useful for industry (e.g., the discovery of penicillin from Penicillium chrysogenum). This discovery was a milestone in the development of white biotechnology as the industrial production of penicillin and antibiotics using fungi moved industrial biotechnology into the modern era, transforming it into a global industrial technology. Since then, white biotechnology has steadily developed and now plays a key role in several industrial sectors providing both high value nutraceutical and pharmaceutical products. The fungal strains and bioactive compounds also play an important role in environmental cleaning. This volume covers the latest research developments related to value-added products in white biotechnology through fungi.

Contents:
Intro; Foreword; Foreword; Preface; Contents;
Chapter 1: Secretomics of Wood-Degrading Fungi and Anaerobic Rumen Fungi Associated with Biodegradation of Recalcitrant Plant Biomass; 1.1 Introduction; 1.2 Degradation and Depolymerization of Plant Biomass; 1.3 Secretomics and Mechanism of Lignocellulose Biodegradation; 1.4 Wood-Degrading Fungi; 1.4.1 Secretomes of White Rot Fungi (WRF); 1.4.2 Secretome of Brown Rot Fungi (BRF); 1.5 Secretome of Anaerobic Rumen Fungi (ARF); 1.6 Conclusion; References;
Chapter 2: Bioremediation: New Prospects for Environmental Cleaning by Fungal Enzymes 2.1 Introduction2.2 Bioremediation; 2.2.1 Types of Bioremediation; 2.2.1.1 Biostimulation; 2.2.1.2 Bioattenuation; 2.2.1.3 Bioaugmentation; 2.2.1.4 Bioventing; 2.2.1.5 Biopiles; 2.2.2 Limitations of Bioremediation; 2.3 Fungi as Bioremediator; 2.3.1 White-Rot Fungi; 2.3.2 Marine Fungi; 2.3.3 Extremophilic Fungi; 2.3.4 Symbiotic Fungi with Plants; 2.4 Fungal Enzymes in Bioremediation; 2.4.1 Enzymological Background; 2.4.1.1 Oxidoreductases; 2.4.1.2 Laccases; 2.4.1.3 Catalase; 2.4.1.4 Peroxidases; 2.4.1.4.1 Lignin Peroxidases; 2.4.1.4.2 Manganese Peroxidases; 2.4.1.4.3 Versatile Peroxidases 2.4.2 Advantages of Enzymatic Bioremediation2.4.3 Disadvantages of Enzymes; 2.4.4 Scope of Enzymatic Bioremediation; 2.5 Conclusion and Future Prospects; References;
Chapter 3: Genetic Diversity of Methylotrophic Yeast and Their Impact on Environments; 3.1 Introduction; 3.2 Genetic Diversity of Methylotrophic Yeast; 3.3 Genetic Regulation in Yeast Methylotrophy; 3.4 Methylotrophic Yeast and Impact to the Environments; 3.5 Conclusion and Future Prospects; References;
Chapter 4: White Rot Fungi and Their Enzymes for the Treatment of Industrial Dye Effluents; 4.1 Introduction; 4.2 Textile Dyes 4.3 Dyes Used in India4.4 Description of Dyeing Process and Sources of Effluent Generation; 4.4.1 Characterization of the Raw Effluents; 4.5 Enzymes of White Rot Fungi; 4.5.1 Lignin Peroxidase (LiP); 4.5.2 Manganese Peroxidase (MnP); 4.5.3 Laccase; 4.6 Factors Influencing Enzyme Production and Dye Degradation; 4.6.1 Effect of Inducers on Enzyme Production; 4.6.2 Effect of Nitrogen Source; 4.6.3 Effect of Carbon Source; 4.6.4 Influence of pH and Temperature; 4.6.5 Concentration of Dye; 4.7 White Rot Fungi and Decolouration; 4.8 White Rot Fungi and Decolourization of Industrial Dye Effluents 4.9 Conclusion and Future ProspectsReferences;
Chapter 5: Pleurotus ostreatus: A Biofactory for Lignin-Degrading Enzymes of Diverse Industrial Applications; 5.1 Introduction; 5.2 Understanding Lignin Structure; 5.2.1 Lignocellulose Processing and Industrial Applications; 5.2.2 Lignin Degradation; 5.3 Laccase (EC 1.1.2.2); 5.3.1 Laccases Structure and Mechanism of Reaction; 5.3.2 Laccase Production and Bioprocessing; 5.3.2.1 Media Composition and Cultivation Conditions; 5.3.2.2 Cultivation Process and Purification; 5.3.3 Applications of Laccase

Summary: The concerns relating to global warming, climate change, and increasing energy demands have led to significant research towards the development of alternative energy to substitute the fossil energy sources. Biomass-based energy or biofuels are highly promising due to many perceptible environmental and socio-economic advantages. Cutting-edge academic research and advanced industrial product development have created tremendous scope for the implementation of biofuels at a global scale to reduce the greenhouse gas emissions and supplement the escalating energy demands. The prime focus of this book is to provide an overview of the different technologies utilized to harness the chemical energy from plant-based non-edible biomass and other organic wastes in the form of solid, liquid, and gaseous biofuels. The opportunities and challenges of different biomass conversion technologies, especially biomass-to-liquid, biomass-to-gas and gas-to-liquid routes, as well as biomass pretreatments, densification, anaerobic digestion, reforming, transesterification, supercritical fluid extraction, microalgal carbon sequestration, life-cycle assessment and techno-economic analysis have been comprehensively discussed in this book. This book is an amalgamation of fifteen different chapters each with distinctive investigations and a collective focus relating to the transition from fossil fuels towards carbon-neutral biofuels. This book serves as a benchmark for academic and industrial researchers involved in exploring the true potentials of plant residues and waste organic matter to produce alternative renewable fuels. To realize the real promises of bioenergy, this book attempts to assess the biorefining approaches, biofuel production and application, and environmental sustainability.

Contents:
Intro; Preface; Contents; Contributors; About the Editors;
1: A Broad Introduction to First-, Second-, and Third-Generation Biofuels; 1.1 Introduction; 1.2 First-, Second-, and Third-Generation Biomass Sources; 1.3 Bioethanol; 1.4 Biobutanol; 1.5 Bio-oil; 1.6 Algal Oil; 1.7 Biodiesel; 1.8 Hydrogen; 1.9 Biomethane; 1.10 Aviation Fuel; 1.11 Conclusions; References;
2: Densification of Agricultural Wastes and Forest Residues: A Review on Influential Parameters and Treatments; 2.1 Introduction; 2.2 Effects of Moisture Content; 2.3 Effects of Pelletization Temperature. 2.4 Effects of Pelletization Pressure (Applied Force)2.5 Effects of Particle Size; 2.6 Effects of Binders and Extractives; 2.7 Biomass Pre-treatments; 2.7.1 Steam Explosion; 2.7.2 Biomass Torrefaction; 2.8 Pellet Post-treatments; 2.8.1 Pellet Coating; 2.8.2 Pellet Torrefaction; 2.9 General Risk Evaluation for Handling and Storage of Biomass Pellets; 2.9.1 Dust Formation; 2.9.2 Self-Ignition and Self-Heating; 2.9.3 Formation of Off-Gases; 2.10 Conclusions; References;
3: An Overview on the Application of Ligninolytic Microorganisms and Enzymes for Pretreatment of Lignocellulosic Biomass. 3.1 Introduction3.2 Composition of Biomass; 3.3 Biological Pretreatment of Biomass: An Overview; 3.4 Application of Lignin-Degrading Microorganisms for Pretreatment of Biomass; 3.5 Application of Ligninolytic Enzymes for Pretreatment of Biomass; 3.6 Factors Affecting Biological Pretreatment of Biomass; 3.7 Conclusions; References;
4: Role of Natural Deep Eutectic Solvents (NADES) in the Pretreatment of Lignocellulosic Biomass for an Integrated Biorefinery ... ; 4.1 Introduction; 4.2 Lignocellulosic Feedstocks; 4.3 Biomass Pretreatment Processes; 4.4 Biological Pretreatment. 4.11.7 Bioethanol Production4.11.8 Carbon Dioxide Sequestration; 4.11.9 Chemical Extraction; 4.12 Technical Assessment of NADES; 4.13 Future Perspective; 4.14 Conclusions; References;
5: Recent Developments and Challenges of Acetone-Butanol-Ethanol Fermentation; 5.1 Introduction; 5.2 Acetone-Butanol-Ethanol (ABE) Fermentation Process; 5.3 Challenges and Possible Outcomes in the ABE Fermentation; 5.4 Conclusions; References;
6: Current Advancements, Prospects and Challenges in Biomethanation; 6.1 Introduction; 6.2 Methanotrophs; 6.3 Bioremediation via Methanotrophy. 4.5 Physical Pretreatment4.6 Physicochemical Pretreatment; 4.7 Chemical Pretreatment; 4.8 Natural Deep Eutectic Solvents (NADES): Synthesis and Mechanism; 4.9 Types of NADES Reagents; 4.9.1 Hydrophilic; 4.9.2 Hydrophobic; 4.10 Physicochemical Properties of NADES; 4.10.1 Structure; 4.10.2 Viscosity; 4.10.3 Density; 4.10.4 Conductivity; 4.10.5 Thermal Properties; 4.10.6 Polarity; 4.11 Functional Properties of NADES; 4.11.1 Specificity; 4.11.2 Toxicity and Biodegradability; 4.11.3 Recyclability; 4.11.4 Biocatalysis; 4.11.5 Biorefinery and Bioprocessing; 4.11.6 Production of Reducing Sugars.

Contents:
Chapter 1: Nutrition and Metabolism: Foundations for Animal Growth, Development, Reproduction, and Health
Chapter 2: Insights into the Regulation of Implantation and Placentation in Humans, Rodents, Sheep, and Pigs
Chapter 3: A Role for Fructose Metabolism in Development of Sheep and Pig Conceptuses
Chapter 4: Nutritional Regulation of Embryonic Survival, Growth and Development
Chapter 5: Phosphate, Calcium, and Vitamin D: Key Regulators of Fetal and Placental Development in Mammals
Chapter 6: Nutritional and Physiological Regulation of Water Transport in the Conceptus
Chapter 7: Amino Acids in Microbial Metabolism and Function
Chapter 8: Potential Replacements for Antibiotic Growth Promoters in Poultry: Interactions at the Gut Level and their Impact on Host Immunity
Chapter 9: Microbiomes in the Intestine of Developing Pigs: Implications for Nutrition and Health
Chapter 10: L-Arginine Nutrition and Metabolism in Ruminants
Chapter 11: Hepatic Glucose Metabolism and Its Disorders in Fish
Chapter 12: Protein-Sourced Feedstuffs for Aquatic Animals
Chapter 13: Functional Molecules of Intestinal Mucosal Products in Animal Nutrition and Health
Chapter 14: Use of Genome Editing Techniques to Produce Transgenic Farm Animals
Chapter 15: Cows as Bioreactors for the Production of Nutritionally and Biomedically Significant Proteins
Chapter 16: Use of Agriculturally Important Animals as Models in Biomedical Research
Chapter 17: Pigs (Sus Scrofa) in Biomedical Research.

Summary: This book discusses the prominence and implication of the viral diseases that are a major threat to animals around the globe. A number of these diseases have also shown links with human populations, which has implications for public health. This book offers detailed and up-to-date information on viral diseases in livestock and poultry that were and/or are still a problem. Including cutting-edge developments, it also highlights several landmark contributions in the field of virology from India. Additionally, the book features tables and figures showing important clinical data and recommendations, with references for further information. It also explores the economic impact of viral diseases for farmers and the livestock industry, providing several examples. Further, it presents the latest information on viral diseases in global context, with a focus on state-of-art, molecular tools for the development of diagnostics, prophylactics and therapeutics. Lastly, the book also describes the challenges posed by the emerging and transboundary viral infections and our preparedness to counter them.

Summary: This book reviews recent advances in the emerging field of computational network biology with special emphasis on comparative network analysis and network module detection. The chapters in this volume are contributed by leading international researchers in computational network biology and offer in-depth insight on the latest techniques in network alignment, network clustering, and network module detection. Chapters discuss the advantages of the respective techniques and present the current challenges and open problems in the field. Recent Advances in Biological Network Analysis: Comparative Network Analysis and Network Module Detection will serve as a great resource for graduate students, academics, and researchers who are currently working in areas relevant to computational network biology or wish to learn more about the field. Data scientists whose work involves the analysis of graphs, networks, and other types of data with topological structure or relations can also benefit from the book's insights.

Contents:
Chapter 1: Global Alignment of PPI Networks
Chapter 2: Integrated Network-Based Computational Analysis for Drug Development
Chapter 3: Effective Random Walk Models for Comparative Network Analysis
Chapter 4: Computational Methods for Protein-Protein Interaction Network Alignment
Chapter 5: Network Propagation for the Analysis of Multi_Omics Data
Chapter 6: Motifs in Biological Networks
Chapter 7: Bio Fabric Visualization of Network Alignments
Chapter 8: Module Identification of Biological Networks via Graph Partition
Chapter 9: Network Module Detection to Decipher the Heterogeneity of Cancer Mutations.