Bookedited by Tahira Farooqui, Department of Entomology, The Ohio State University, Columbus, OH, United States ; Akhlaq A. Farooqui, Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, United States.
Summary: Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD) and Amyotrophic Lateral Sclerosis (ALS), also providing information on how cardiovascular disease, Type 2 Diabetes, and Metabolic Syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction. The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline. Comprehensively provides an overview of the effects of the Mediterranean diet on the brain and its beneficial effects in neurodegenerative diseases. Discusses the relationship among Type 2 Diabetes, Metabolic Syndrome and Alzheimer's Disease, and the effect of the Mediterranean diet on normal aging, longevity, and other neurodegenerative diseases. Focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative disease
Contents:
Effects of Mediterranean diet components on neurodegenerative diseases
The Mediterranean ddiet and healthy brain aging: innovations from nutritional cognitive neuroscience
Molecular and intracellular signaling mechanisms of herbs, spices, and food components in the Mediterranean diet in improving cognitive function
The molecular basis for protective effect of Mediterranean diet in neurodegenerative disorders
Multinutrient approach to slow down brain aging and related neurodegenerative disorders
Effect of Mediterranean diet on healthy brain aging: involvement of telomerase
Mediterranean diet and dementia: can this be a preventive approach?
Effects of dietary components on microglia inactivation in Alzheimer's disease
Contribution of Mediterranean diet in the prevention of Alzheimer's disease
Mediterranean diet and its impact on cognitive functions in aging
Mediterranean diet and diabetic retinopathy
Mediterranean diet as a potential strategy to reduce cognitive decline and dementia in the elderly
Effect of Mediterranean diet components on type 2 diabetes and metabolic syndrome
Interactions between age, diet, and insulin and their effect on cognition: implications for Alzheimer's disease
The use of polyphenols for the treatment of Alzheimer's disease
Neuroprotective effects of garlic in model systems of neurodegenerative diseases
Neuroprotective properties of wine: implications for the prevention of cognitive impairment
Red wine retards abeta deposition and neuroinflammation in Alzheimer's disease
Contribution of diabetes and metabolic syndrome in the pathogenesis of Alzheimer's disease
Effects of Western, Mediterranean, vegetarian, and Okinawan diet patterns on human brain
Mediterranean diet is beneficial: but, how, and why?
Multinutrient intervention in the prevention and treatment of dementia
Cardioprotective properties of wine: implications for the management of neurodegenerative diseases
Antiinflammatory properties of dietary n-3 polyunsaturated fatty acids protect against cognitive decline in aging and neurodegenerative diseases
Effects of dietary omega-3 fatty acid consumption
Interplay between lipid mediators and immune system in the promotion of brain self-repair
Importance of fruit and vegetable-derived flavonoids in the Mediterranean diet: molecular and pathological aspects
Perspective and directions for future research.