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  • Book
    Da-Cheng Hao.
    Summary: Ranunculales is an order of flowering plants belonging to a paraphyletic group known as the basal eudicots. Medicinal plants of this order provide myriad pharmaceutically active components commonly used worldwide in ethnomedicine and traditional Chinese medicine. Interest in plant-based medicinal resources has led to discoveries of many novel compounds in various species, and to investigations on their chemodiversity, biodiversity and pharmacotherapy. Ranunculales Medicinal Plants covers this order of flowering plants comprehensively in this context; detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera, and their relevance to drug efficacy. The book carries out an exhaustive survey of the literature in order to characterize global trends in the application of flexible technologies. The interrelationship between Chinese species and between Chinese and non-Chinese species is inferred, in the text, through molecular phylogeny, based on nuclear and chloroplast DNA sequencing. The title discusses the conflict between chemotaxonomy and molecular phylogeny, in the context of drug discovery and development. It offers invaluable and holistic coverage for the study of Ranunculales as a pharmaceutical resource.

    Contents:
    Genomics and evolution of medicinal plants
    Mining chemodiversity from biodiversity: pharmacophylogeny of Ranunculaceae medicinal plants
    Mining chemodiversity from biodiversity: pharmacophylogeny of Ranunculales medicinal plants (except Ranunculaceae)
    Drug metabolism and pharmacokinetic diversity of Ranunculaceae medicinal compounds
    Drug metabolism and disposition diversity of Ranunculales phytometabolites
    Anticancer chemodiversity of Ranunculaceae medicinal plants
    Biodiversity, chemodiversity, and pharmacotherpy of Thalictrum medicinal plants
    Biodiversity, chemodiversity, and pharmacotherapy of Anemone medicinal plants
    Biodiversity, chemodiversity, and pharmacotherapy of Ranunculus medicinal plants
    Index.
    Digital Access ScienceDirect 2018