BookArti Gupta, Nagendra Pratap Singh, editors.
Summary: Fungal growths affect both human and animal well-being. Many natural pathogens of laboratory animals alter host physiology, rendering the host unsuitable for experimental uses. While the number and prevalence of few pathogens have declined considerably, many still turn up in laboratory animals and represent unwanted variables in research. Investigators using laboratory animals in biomedical experimentation should be aware of the profound effects that many of these agents can have on research. What does the future hold regarding the natural pathogens of laboratory animals? The selection of an animal model must carefully address issues of the type of human disease to mimic, the parameters to follow, and the collection of the appropriate data to answer those questions being asked. Overall, animal models of fungal infection will continue to deepen our understanding of how these infections occur. This book provides a valuable source of information to biological and biomedical scientists and to clinical and doctoral researchers working in the area of fungal infections and diseases of laboratory animal species.
Contents:
Intro; Preface; Acknowledgements; Contents; About the Editors;
Chapter 1: Emerging Infectious Diseases Caused by Fungi in Animals and Their Prevention; 1.1 Introduction; 1.2 Fungal Diseases in Animals; 1.3 Factors Affecting the Transmission of Diseases and Their Control Measures; 1.4 Conclusions and Future Prospects; References;
Chapter 2: Fungal Diseases of Honey Bees: Current Status and Future Perspective; 2.1 Introduction; 2.2 Major Milestones in Microsporidia Research; 2.3 Morphology of Microsporidia; 2.3.1 Life Cycle; 2.4 Geographical Distribution 2.5 Factors Affecting Microsporidian Infection2.6 Lacunae in Knowledge; 2.7 Knowledge of the Pathogen So Far; 2.8 Pathogenesis; 2.8.1 Physiological and Behavioral Perturbation in Honey Bees; 2.9 Treatment; 2.9.1 Diagnosis; 2.10 Occurrence of Other Fungal Pathogens; 2.10.1 Stonebrood Disease; 2.10.2 Chalkbrood Disease; 2.11 Parasitized Honey Bee Immune Gene Suppression; 2.12 Conclusion; 2.12.1 Future Directions; 2.12.2 New Insights; References;
Chapter 3: Immunological Diagnosis of Fungal Disease in Animals; 3.1 Introduction; 3.2 Laboratory Testing for Fungal Identification 3.3 Microscopic and Macroscopic Examination3.4 Immunology of Fungal Infection; 3.5 Immunological Techniques for Fungal Diseases; 3.6 Immunofluorescence; 3.7 Immunoperoxidase Staining; 3.8 Counter-Immunoelectrophoresis (CIE); 3.9 Immunodiffusion (ID); 3.10 Immunoblotting; 3.11 Latex Particle Agglutination; 3.12 Tube Precipitin and Complement Fixation Tests; 3.13 Enzyme-Linked Immunosorbent Assay (ELISA); 3.14 Antigens Useful for Diagnosis; 3.15 Conclusion; 3.16 Future Prospects; References;
Chapter 4: Aspergillosis in Birds and Mammals: Considerations for Veterinary Medicine; 4.1 Introduction 4.10 Conclusions and Future DirectionsReferences;
Chapter 5: Fungal Diseases of Animals: Symptoms and Their Cure by Natural Products; 5.1 Introduction; 5.2 Mechanism of Antibiotic Action; 5.3 Mechanism of Antibiotic Resistance; 5.4 Methodology for Carrying Out Antibacterial Activity; 5.4.1 Cleaning of Glassware; 5.4.2 Sterilization; 5.4.2.1 Dry Heat Sterilization; 5.4.2.2 Moist Heat Sterilization; 5.4.2.3 Direct Flaming; 5.4.2.4 Ultraviolet (UV) Sterilization; 5.4.3 Preparation of Culture Media; 5.5 Evaluation of Antibacterial Activity by Agar Well Diffusion Method 4.2 Epidemiology4.2.1 Aspergillosis in Mammals; 4.2.2 Aspergillosis in Birds; 4.2.3 Susceptibility of Various Birds; 4.2.3.1 Free-Ranging Birds; 4.2.3.2 Domestic (Poultry) Birds; 4.2.3.3 Captive Birds (Companion, Rehabilitated, and Zoological Collection); 4.2.3.3.1 Companion Birds; 4.2.3.3.2 Rehabilitation/Zoological Collection Birds; 4.3 Etiology; 4.4 Clinical Signs; 4.5 Antemortem Diagnostics; 4.6 Culture and Identification; 4.7 Postmortem Evaluation; 4.8 Treatment; 4.9 Prevention; 4.9.1 Monitoring and Epidemiology; 4.9.2 Vaccination; 4.9.3 Environmental Control