Bookedited by Mouldy Sioud.
Contents:
RNA interference : mechanisms, technical challenges, and therapeutic opportunities / Mouldy Sioud
Nanostructured RNAs for RNA interference / Yuko Nakashima [and others]
One long oligonucleotide or two short oligonucleotides based shRNA construction and expression / Xue-jun Wang and Sheng-qi Wang
PLGA microspheres encapsulating siRNA / Giuseppe De Rosa and Giuseppina Salzano
Magnetic nanoparticle and magnetic field assisted siRNA delivery in vitro / Olga Mykhaylyk [and others]
Cytoplasmic delivery of siRNAs to monocytes and dendritic cells via electroporation / Mouldy Sioud
Delivery of siRNAs to cancer cells via bacteria / Omar Ahmed, Andrea Krühn, and Hermann Lage
Microwell array-mediated delivery of lipoplexes containing nucleic acids for enhanced therapeutic efficacy / Yun Wu, Daniel Gallego-Perez, and L. James Lee
Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy / Karin Zins [and others]
Targeted in vivo delivery of siRNA and an endosome- releasing agent to hepatocytes / Magdolna G. Sebestyén [and others]
Cell-internalization SELEX : method for identifying cell- internalizing RNA aptamers for delivering siRNAs to target cells / William H. Thiel [and others]
Strategies for siRNA navigation to desired cells / Mouldy Sioud
Use of guanidinopropyl-modified siRNAs to silence gene expression / Maximilian C.R. Buff [and others]
Therapy of respiratory viral infections with intranasal siRNAs / Sailen Barik and Patrick Lu
Engineering therapeutic cancer vaccines that activate antitumor immunity / Per Ole Iversen and Mouldy Sioud
Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses / Mouldy Sioud, Anne Mobergslien, and Stein Sæbøe-Larssen
Targeting bcr-abl transcripts with siRNAs in an imatinib- resistant chronic myeloid leukemia patient : challenges and future directions / Michael Koldehoff
Facile method for interfering with off-target silencing mediated by the sense strand / Anne Mobergslien and Mouldy Sioud
Overcoming the challenges of siRNA activation of innate immunity : design better therapeutic siRNAs / Mouldy Sioud
Gene silencing in vitro and in vivo using intronic microRNAs / Jia Han Deng [and others]
In silico identification of novel endo-siRNAs / Andrew Schuster [and others]
Computer-assisted annotation of small RNA transcriptomes / Nicole Ortogero [and others]
miR-CATCH : microRNA capture affinity technology / Sebastian Vencken [and others]
Roles of MicroRNAs in cancers and development / Shigeru Takasaki
Targeting microRNAs to withstand cancer metastasis / Valentina Profumo [and others]
Urinary microRNAs as a new class of noninvasive biomarkers in oncology, nephrology, and cardiology / Hana Mlcochova [and others]
Magnetic bead-based isolation of exosomes / Morten P. Oksvold, Axl Neurauter, and Ketil W. Pedersen
Modified 2'-ribose small RNAs function as toll-like receptor-7/8 antagonists / Mouldy Sioud.