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  • Print Material
  • R book 2007
    Wiley
    Preface -- 1. Getting started -- 2. Essentials of the R language -- 3. Data input -- 4. Dataframes -- 5. Graphics -- 6. Tables -- 7. Mathematics -- 8. Classical tests -- 9. Statistical modelling -- 10. Regression -- 11. Analysis of variance -- 12. Analysis of covariance -- 13. Generalized linear models -- 14. Count data -- 15. Count data in tables -- 16. Proportion data -- 17. Binary response variables -- 18. Generalized additive models -- 19. Mixed-effects models -- 20. Non-linear regression -- 21. Tree models -- 22. Time series analysis -- 23. Multivariate statistics -- 24. Spatial statistics -- 25. Survival analysis -- 26. Simulation models -- 27. Changing the look of graphics -- References and further reading -- Index.
  • "Focusing on user-developed programming, An R Companion to Linear Statistical Models serves two audiences: Those who are familiar with the theory and applications of linear statistical models and wish to learn or enhance their skills in R; and those who are enrolled in an R-based course on regression and analysis of variance. For those who have never used R, the book begins with a self-contained introduction to R that lays the foundation for later chapters.This book includes extensive and carefully explained examples of how to write programs using the R programming language. These examples cover methods used for linear regression and designed experiments with up to two fixed-effects factors, including blocking variables and covariates. It also demonstrates applications of several pre-packaged functions for complex computational procedures"-- Provided by publisher.
  • R cookbook. 1st ed. 2011
    ProQuest Safari
  • Print Material
  • R graphics 2006
    CRCnetBASE
  • R graphics. 2nd ed. 2011
    CRCnetBASE
    An introduction to R graphics -- Traditional graphics. Simple usage of traditional graphics -- Customizing traditional graphics -- Grid graphics. Trellis graphics : the lattice package -- The grammar of graphics : the ggplot2 package -- The grid graphics model -- The grid graphics object model -- Developing new graphics functions and objects -- The graphics engine. Graphics formats -- Graphical parameters -- Graphics packages. Graphics extensions -- Plot extensions -- Graphics for categorical data -- Maps -- Node-and-edge graphs -- 3D graphics -- Dynamic and interactive graphics -- Importing graphics -- Combining graphics systems.
  • R in a nutshell 2010
    ProQuest Safari
  • R primer 2012
    CRCnetBASE
  • Rabies 2002
    ScienceDirect
  • Rabies is the deadliest zoonotic disease that threatens humans and animals on all continents except Antarctica. Asia and Africa are worst affected as more than 95 per cent of rabies associated human deaths occur in these regions. India alone bears about 36 per cent of the global human rabies burden. Dogs are the main transmitters of rabies that potentially threaten over 3 billion people in Asia and Africa. Many developed nations have been able to successfully control dog rabies but continue to face the risk from wildlife including bats.
  • History of rabies research -- Rabies virus -- Epidemiology -- Molecular epidemiology -- Rabies in terrestrial animals -- Bat rabies -- Human disease -- Pathogenesis -- Pathology -- Immunology -- Laboratory diagnosis of rabies -- Measures of rabies immunity -- Rabies vaccines -- Next generation of rabies vaccines -- Public health management of humans at risk -- Therapy of human rabies -- Dog rabies and its control -- Rabies control in wild carnivores -- Blueprint for rabies prevention and control -- Future developments and challenges.
  • The role of disaster medicine is becoming more important as the frequency and severity of natural and technological disasters increase. The triple disaster that occurred in Fukushima on March 11, 2011 calls for innovation in the training of health care professionals, pre-hospital emergency care providers, and emergency personnel in the management of the medical consequences of radiation disasters. While many books are available on disaster medicine, none is specifically devoted to the role of physicians in the management of patients exposed to radiation leakage from a damaged nuclear power plant. Radiation Disaster Medicine aims to fill this void based on the response to the Fukushima nuclear accident. Each chapter addresses principles and practices of radiation medicine within the specific context of that accident. Topics covered include the role of physicians in radiation disasters, the concepts of external and internal exposure, prehospital and hospital response, disaster behavioral health, and radiation emergency response from the perspective of national and international institutions. Most of the contributors are active educators and researchers in radiation medicine with first-hand experience in dealing with prehospital triage and management of patients within secondary and tertiary care hospitals in Japan. It is hoped that this book will assist in attaining the ultimate goal of radiation disaster medicine: to help the patients.
  • Multi-Detector Row CT-Recent Developments, Radiation Dose and Dose Reduction Technologies / Thomas Flohr -- Clinical Expansion of CT and Radiation Dose / Stuart Meeson, Rajesh Patel and Stephen Golding -- Risks from Ionising Radiation / Kenneth H. Chadwick and Hendrik P. Leenhouts -- The Cancer Risk from Low Level Radiation / Bernard L. Cohen -- Image Quality in CT: Challenges and Perspectives / Thomas L Toth -- Radiation Dose Metrics and the Effect of CT Scan Protocol Parameters / Sue Edyvean, Maria Lewis and Alan Britten -- Scan Parameters and CT Radiation Dose / Sarabjeet Singh and Mannudeep K. Kalra -- Optimization of Tube Potential for Radiation Dose Reduction in CT / Lifeng Yu, Joel G. Fletcher and Cynthia H. McCollough -- Conventional and Newer Reconstruction Techniques in CT / Homer Pien, Synho Do, Sarabjeet Singh and Mannudeep K. Kalra -- Image Noise Reduction Filters / Sarabjeet Singh and Mannudeep K. Kalra -- Hardware Developments for Radiation Dose Reduction / Rich Mather -- Application of Shielding in CT Radiation Dose Reduction / Shima Aran, Sarabjeet Singh and Mannudeep K. Kalra -- Radiation Dose: Records and Audits / Tessa S. Cook, William W. Boonn and Woojin Kim -- Collective Radiation Dose from MDCT: Critical Review of Surveys Studies / Georg Stamm. ALARA Concept for MDCT Optimization: What is Reasonable, What is Achievable? / Denis Tack -- Automatic Exposure Control in Multidetector-row CT / Mannudeep K. Kalra -- Patient Centering in MDCT: Dose Effects / Mannudeep K. Kalra and Thomas L. Toth -- Dose Optimization and Reduction in CT of the Brain and Head and Neck Region / Tom Mulkens, Rodrigo Salgado and Patrick Bellinck -- Dose Reduction and Optimization in Computed Tomography of the Chest / Pierre Alain Gevenois and Denis Tack -- Dose Optimization and Reduction in MDCT of the Abdomen / Caroline Keyzer and Denis Tack -- Radiation Dose Optimisation of Cardiac and Vascular MDCT in Adults and Paediatric Patients / Jean François Paul, Caroline Keyzer, Michelle Williams and Denis Tack -- Dose Optimization and Reduction in Musculoskeletal CT Including the Spine / A. Gervaise, P. Teixeira, N. Villani, S. Lecocq and M. Louis, et al. -- Dose Reduction in CT Fluoroscopy / N. Buls, F. Vandenbroucke and J. de Mey -- Dose Optimization and Reduction in CT of Children / Peter Vock, Enno Stranzinger and Rainer Wolf -- CT Scanning in Pregnancy / D. E. Litmanovich and A. A. Bankier -- Radiation Risk Associated with Lung Cancer Screening / Cornelia Schaefer-Prokop, Krijn van Muiswinkel and Mathias Prokop. Dose Reduction in Screening Programs: Colon Cancer Screening / Thierry N. Boellaard, Henk W. Venema and Jaap Stoker -- CT Dose Perspectives and Initiatives of the IAEA / Madan M. Rehani and Olivera Ciraj-Bjelac -- The Image Gently Campaign: Championing Radiation Protection for Children Through Awareness, Educational Resources and Advocacy / Marilyn J. Goske, Michael J. Callahan, Donald P. Frush, Sue C. Kaste and Gregory Morrison, et al. -- CT Radiation Dose and Safety: Perspectives at the U.S. Food and Drug Administration / Stanley H. Stern, Sean Boyd, Kish Chakrabarti, Iacovos S. Kyprianou and Thalia T. Mills, et al. -- ICRP's Role in Patient Dose Management in CT / Madan M. Rehani -- Software for Calculating Dose and Risk / Georg Stamm -- Image Wisely / James A. Brink and E. Stephen Amis -- Guidelines for Appropriate CT Imaging / Kristie M. Guite, J. Louis Hinshaw, Frank N. Ranallo and Fred T. Lee -- Practical Approaches to Dose Reduction: GE Perspective / Roy A. Nilsen -- Dose Reduction in Computed Tomography Siemens Perspective / Christianne Leidecker and Bernhard Schmidt -- CT Radiation Dose: Philips Perspective / Alain Vlassenbroek, Dhruv Mehta and Jeffrey Yanof -- Practical Approaches to Dose Reduction: Toshiba Perspective / Jacob Geleijns and R Irwan.
  • Ch. 1. Growing health concerns with respect to low doses of ionizing radiation : can we prevent and/or mitigate them? -- ch. 2. Physics of radiological weapons and nuclear reactors -- ch. 3. Acute radiation damage by high doses of ionizing radiation in humans -- ch. 4. Long-term damages among survivors of high doses of ionizing radiation -- ch. 5. Prevention and mitigation of acute radiation sickness (ARS) -- ch. 6. Prevention and mitigation of late adverse effects of high radiation doses -- ch. 7. Health risks of low doses of ionizing radiation -- ch. 8. Prevention and mitigation against radiological weapons and nuclear plant accidents -- ch. 9. Prevention and mitigation of damage after low radiation doses -- ch. 10. Implementation plans for prevention and mitigation of radiation injury -- ch. 11. Health risks of nonionizing radiation and their prevention and mitigation.
  • Central Nervous System Tumors: Adult and Pediatric -- Skin Cancer -- Head and Neck Cancer -- Lung Cancer -- Tumors of the Mediastinum -- Breast Cancer -- Upper Gastrointestinal Cancers -- Lower Gastrointestinal Cancers -- Urinary System Cancers -- Male Genitourinary Cancer -- Gynecologic Malignancies -- Hematologic Malignancies -- Sarcoma -- Pediatric Non-central Nervous System Cancers -- Benign and Metastatic Disease.
  • Radiation Physics -- Radiobiology -- Clinical Radiation Oncology -- Central Nervous System Tumors -- Head and Neck Cancers -- Lung Cancer -- Breast Cancer -- Genitourinary System Cancers -- Gynecological Cancers -- Gastrointestinal System Cancers -- Soft Tissue Sarcoma -- Skin Cancer -- Lymphomas and Total Body Irradiation -- Pediatric Tumors -- Rare Tumors and Benign Diseases.
  • Ideal for on-the-spot consultation, this pocket manual, Radiation Oncology: Management Decisions, provides easily accessible information for residents and practitioners in radiation oncology. It presents the most essential information that is immediately required in the clinical setting. The first eight chapters of the book focus on key basic concepts; the remaining 46 chapters describe treatment regimens for all cancer sites and tumor types. Includes coverage of pain and palliation, and covers all latest therapeutic techniques. This edition includes expanded information on image-guided therapy, 3D techniques, and 4D protocols. The updated cancer staging guidelines have been used throughout the manual. In addition, there is a brand-new chapter devoted to QUANTEC dosage recommendations.
  • Radiation Oncology: Rationale, Technique, Results, by James D. Cox, MD and K. Kian Ang, MD, PhD, provides you with authoritative guidance on the latest methods for using radiotherapy to treat patients with cancer. Progressing from fundamental principles through specific treatment strategies for the cancers of each organ system, it also addresses the effects of radiation on normal structures and the avoidance of complications. This 9th edition covers the most recent indications and techniques in the field, including new developments in proton therapy and intensity-modulated radiotherapy (IMRT). It also features, for the first time, full-color images throughout the text to match those that you see in practice, and uses new color-coded treatment plans to make targets, structures, and doses easier to read at a glance. Evidence from randomized clinical trials is included whenever possible to validate clinical recommendations. The state-of-the-art coverage inside this trusted resource equips you to target cancer as effectively as possible while minimizing harm to healthy tissue. Stands apart as the only book in the field to cover the conceptual framework for the use of radiotherapy by describing the most effective techniques for treatment planning and delivery and presenting the results of each type of therapy. Emphasizes clinical uses of radiation therapy, providing pertinent, easy-to-understand information on state-of-the-art treatments. Includes information useful for non-radiotherapists, making it "recommended reading" for other oncology specialists. Offers a practical, uniform chapter structure to expedite reference.
  • The role of radiation physics in nuclear medicine -- The molecular imaging pathway to biomedical physics -- Mechanisms of the interactions between radiation and matter -- Principles of monte carlo calculations and codes -- Sealed radionuclide and X-Ray sources in nuclear medicine -- Radiopharmaceutical production -- Research and development of new radiopharmaceuticals -- Basic principles of detection of ionizing radiation used in medical imaging -- Scintillators and semiconductor detectors -- New trends in detectors for medical imaging -- The PET magnifier probe -- Algorithms for image reconstruction -- Biokinetic models for radiopharmaceuticals -- Voxel phantoms for internal dosimetry.
  • This book explains clearly and in detail all aspects of radiation protection in nuclear medicine. After an introductory chapter on the general role of radiation protection, measurement quantities and units are discussed, and detectors and dosimeters, described. Radiation biology and radiation dosimetry are then addressed, with the inclusion of a chapter specifically devoted to biology and dosimetry for the lens of the eye. Discussion of radiation doses to patients and to embryos, fetuses, and children forms a central part of the book. Phantom models, biokinetic models, calculations, and software solutions are all considered, and a further chapter focuses on quality assurance and reference levels. Occupational exposure also receives detailed attention. Exposure resulting from the production, labeling, and injection of radiopharmaceuticals and from contact with patients is discussed and shielding calculations are explained. The book closes by considering exposure of the public and summarizing the "rules of thumb" for radiation protection in nuclear medicine. This is an ideal textbook for students and a ready source of useful information for nuclear medicine specialists and medical physics experts.
  • This book provides a state-of-the-art review of the role of radiation therapy in various pelvic malignancies as well as the consequences of the radiation in the pelvic tissues. With sections covering the role of radiation therapy in the various pelvic malignancies, the pathophysiology of radiation related injury and the risk factors that increase the possibility of such an injury, and the latest in medical, endoscopic and surgical therapies for these radiation related complications the text offers a concise yet comprehensive overview of radiation therapy in the human pelvis, its role and the adverse effects on the pelvic organs. Written by experts in the field with readers in mind, Radiation Therapy for Pelvic Malignancy and its Consequences is the first of its kind standalone reference on the subject. ℗ℓ Radiation Therapy for Pelvic Malignancy and its Consequences is of great value to urologists, medical radiation and gynecological oncologists, and gastroenterologists.
  • History of radiation therapy in dermatology -- Radiobiology -- Physical aspects of dermatological radiotherapy -- Radiation protection -- Staging of squamous cell carcinoma and basal cell carcinoma -- Acute and chronic cutaneous reactions to radiotherapy -- Efficacy of superficial radiotherapy -- Treatment selection for superficial radiotherapy -- Superficial radiation therapy treatment planning -- Current use of dermatologic radiotherapy in the United States -- Grenz ray therapy -- Radiotherapy for cutaneous squamous and basal cell carcinomas -- Brachytherapy -- Cutaneous merkel cell carcinoma -- Radiotherapy for cutaneous angiosarcoma -- Radiotherapy for dermatofibrosarcoma protuberans -- Squamous and basal cell carcinomas with perineural invasion -- Getting started in superficial radiation for the dermatology practice.
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    Atomic structure and radioactive decay -- Production of x rays -- Interactions of x rays and gamma rays -- Radiation units -- Measurement of ionizing radiation -- Calibration of megavoltage beams of x rays and electrons -- Dosimetry of radiation fields -- Treatment planning by manual methods -- Diagnostic imaging and applications to radiation therapy -- Computer systems -- Computer-based treatment planning -- Sources for implant therapy -- Brachytherapy treatment planning -- Radiation protection -- Quality assurance -- Advances in radiation therapy -- Answers to selected problems.
  • In this book, leading experts in the dermatological and oncological field describe the use of radiation therapy for the treatment of the full range of dermatological malignancies ? including basal cell carcinoma, squamous cell carcinoma, cutaneous lymphomas, Kaposi's sarcoma, melanoma, and Merkel cell tumor ? as well as those precancerous lesions and non-malignant dermatological disorders which are amenable to radiation therapy. In each case the specific indications for the use of radiotherapy and its application are clearly explained with the aid of numerous high-quality illustrations. In addition, the book provides a concise introduction to physical and radiobiological principles, selection of radiation factors, dose definitions, radiation reactions, and risk assessments. The new edition has been thoroughly revised and updated to reflect advances in practical knowledge and clinical practice. It will be an invaluable source of information on the management of skin tumors and related non-malignant disorders for both dermatologists, oncologists and radiation oncologists.
  • Nuclear Radiation, Ionization, and Radioactivity -- Radiation Exposure: Consequences, Detection, and Measurements -- Mathematical Modeling of Radiation -- Medical Imaging -- Basic Principles of Radiation Detectors -- Theoretical Approach of Crystal and Film Growths of Materials Used in Medical Imaging System -- Device Fabrication (Scintillators/Radiation Detectors) -- Characterization of Radiation Detectors (Scintillators) Used in Nuclear Medicine -- Instrumentation and Its Applications in Nuclear Medicine.
  • Radical Prostatectomy: Surgical Perspectives provides surgeons with a comprehensive overview of the anatomical approach to radical prostatectomy, whether done through an open (retropubic) or robotic-assisted laparoscopic approach. All chapters are structured to provide a step-by-step approach to the most technically demanding and most common oncologic procedure in urology surgery. The book includes highly practical presentations of typical surgical patients seen in the clinical practice of urology and relies heavily on illustrations and intraoperative photographs to clearly complement the text. In addition, the book ?includes a detailed description of the management of uncommon but potentially serious intraoperative complications, including major vascular injury, ureteral transaction, and rectotomy. Written by authors from a variety of integrated disciplines, including anesthesia, cardiology, and nursing Radical Prostatectomy: Surgical Perspectives is a unique and valuable resource in the field of urology both for those currently in training and for those already in surgical practices.
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    [1] Basic physics and instrumentation by E. H. Quimby [and others]--[2] Medicine, by S. S. Silver.
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    Physics and chemistry of radiation absorption -- DNA strand breaks and chromosomal aberrations -- Cell survival curves -- Radiosensitivity and cell age in the mitotic cycle -- Repair of radiation damage and the dose-rate effect -- Oxygen effect and reoxygenation -- Linear energy transfer and relative biologic effectiveness -- Acute effects of total-body irradiation -- Radioprotectors -- Radiation carcinogenesis -- Hereditary effects of radiation -- Effects of radiation on the embryo and fetus -- Radiation cataractogenesis -- Doses and risks in diagnostic radiology, interventional radiology and cardiology, and nuclear medicine -- Radiation protection -- Molecular techniques in radiobiology -- Cancer biology -- Dose-response relationships for model normal tissues -- Clinical response of normal tissues -- Model tumor systems -- Cell, tissue, and tumor kinetics -- Time, dose, and fractionation in radiotherapy -- Predictive assays -- Alternative radiation modalities -- Radiosensitizers and bioreductive drugs -- Gene therapy -- Chemotherapeutic agents from the perspective of the radiation biologist -- Hyperthermia.
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    Physics and Chemistry of Radiation Absorption -- Molecular Mechanisms of DNA and Chromosome Damage and Repair -- Cell Survival Curves -- Radiosensitivity and Cell Age in the Mitotic Cycle -- Fractionated Radiation and the Dose-Rate Effect -- Oxygen Effect and Reoxygenation -- Linear Energy Transfer and Relative Biologic Effectiveness -- Acute Radiation Syndrome -- Radioprotectors -- Radiation Carcinogenesis -- Heritable Effects of Radiation -- Effects of Radiation on the Embryo and Fetus -- Radiation Cataractogenesis -- Radiologic Terrorism -- Molecular Imaging -- Doses and Risks in Diagnostic Radiology, Interventional Radiology and Cardiology, and Nuclear Medicine -- Radiation Protection -- Cancer Biology -- Dose-Response Relationships for Model Normal Tissues -- Clinical Response of Normal Tissues -- Model Tumor Systems -- Cell, Tissue, and Tumor Kinetics -- Time, Dose, and Fractionation in Radiotherapy -- Retreatment after Radiotherapy: The Possibilities and the Perils -- Alternative Radiation Modalities -- The Biology and Exploitation of Tumor Hypoxia -- Chemotherapeutic Agents from the Perspective of the Radiation Biologist -- Hyperthermia.
  • "Despite the advent of modern cross-sectional imaging, skeletal radiographs remain at the crux of the initial diagnosis, particularly in the emergency and outpatient settings. The images contained herein represent composite individuals obtained at three-month intervals for the first two years of life and at yearly intervals thereafter. The authors provide a comprehensive set of reference images that document the progressive skeletal development, demonstrating the configuration, density, and relative size of the various body parts for males and females. Given the broad application of radiographs in the clinical setting, this atlas is not only intended for practicing and training radiologists, but for all of those who employ radiographs as part of their practice"--Provided by publisher.
  • Part I. Chemistry and Physics -- Radiopharmaceuticals for Radioguided Surgery / Esteban Obenaus, Paola A. Erba, Marco Chinol, Christophe Van de Wiele and Gyozo A. Janoki, et al. -- Physical Performance Parameters of Intraoperative Probes / Carlo Chiesa, Francesca Toscano, Mario Mariani and Emilio Bombardieri -- Positron-Sensitive Probes / Schlomo Schneebaum, Richard Essner and Einat Even-Sapir -- Gamma Ray Imaging Probes for Radioguided Surgery and Site-Directed Biopsy / Francesco Scopinaro and Alessandro Soluri -- Radiation Protection in Radioguided Surgery / Edwin C. Glass and Wendy A. Waddington -- Training and Credentialing for Radioguided Surgery / Eric D. Whitman -- Part II. Sentinel Lymph Nodes -- The Anatomy and Physiology of Lymphatic Circulation / Preya Ananthakrishnan, Giuliano Mariani, Luciano Moresco and Armando E. Giuliano -- The Role of Lymph Node Staging for Clinical Decision Making in Patients with Solid Cancers / Fausto Badellino, Ilaria Pastina, Elisa Borsò, Sergio Ricci and H. William Strauss, et al. -- Sentinel Lymph Node Biopsy in Patients with Breast Cancer / Charles E. Cox, John M. Cox, Giuliano Mariani, Caren E.G. Wilkie and Laura B. White, et al. -- Sentinel Lymph Node Biopsy in Cutaneous Melanoma / Jeffrey E. Gershenwald, Roger F. Uren, Giuliano Mariani and John F. Thompson -- Dynamic Sentinel Lymph Node Biopsy in Penile Carcinoma / Simon Horenblas, Bin K. Kroon, Renato A. Valdés Olmos and Omgo E. Nieweg -- Sentinel Lymph Node Biopsy in Cancer of the Head and Neck / Luca Calabrese, David Soutar, Jochen Werner, Roberto Bruschini and Concetta De Cicco, et al. -- Sentinel Lymph Node Biopsy in Gynecologic Malignancies / Emilio Bombardieri, Marco Maccauro, Rosanna Fontanelli, Francesco Raspagliesi and Giovanni Paganelli -- Sentinel Lymph Node Biopsy in Cancers of the Gastrointestinal Tract / Yuko Kitagawa, Sukamal Saha and Masaki Kitajima -- Sentinel Lymph Node Biopsy in Prostatic Cancer / Alexander Winter, Harry Vogt, Dorothea Weckermann, Rolf Harzmann and Friedhelm Wawroschek -- Radioguided Biopsy of the Sentinel Lymph Node in Patients with Non-Small Cell Lung Cancer / Giuseppe Boni, Gianpiero Manca, Franca M. A. Melfi, Marco Lucchi and Alfredo Mussi, et al. -- Sentinel Lymph Node Biopsy in Thyroid Cancer / Massimo Salvatori, Domenico Rubello, Michael J. O'Doherty, Maria Rosa Pelizzo and Giuliano Mariani -- Histopathology of Sentinel Lymph Nodes / Giuseppe Viale, Giovanni Mazzarol and Eugenio Maiorano -- Frozen Section and Imprint Cytology in Sentinel Lymph Node Biopsy for Breast Cancer / Santo V. Nicosia and Charles E. Cox -- Molecular Assessment of Sentinel Lymph Nodes / Farin Amersi, Armando E. Giuliano and Dave S.B. Hoon -- Part III. Occult Lesion Localization -- Where It All Began: The Heritage of Radioimmunoguided Surgery / Fausto Badellino, Mario Roselli, Marzio Perri, Fiorella Guadagni and Giuliano Mariani -- Radioguided Occult Lesion Localization in the Breast / Giovanni Paganelli, Concetta De Cicco, Giovanna Gatti and Alberto Luini -- Minimally Invasive Radioguided Parathyroidectomy in Primary Hyperparathyroidism / James Norman, Domenico Rubello, Armando E. Giuliano and Giuliano Mariani -- Radioguided Surgery of Neuroendocrine Tumors / Richard P. Baum, Sergio Sandrucci and Stefan Adams -- Radioguided Surgery of Solitary Pulmonary Nodules / Giuseppe Boni, Franca M. A. Melfi, Gianpiero Manca, Marco Lucchi and Alfredo Mussi, et al. -- Radioguided Surgery of Occult Lesions in Patients with Thyroid Cancer / Domenico Rubello, Massimo Salvatori, Maria Rosa Pelizzo, Giuseppe Boni and Giuliano Mariani -- Radioguided Bone Lesion Localization / Gianpiero Manca, Giuliano Mariani and Lary A. Robinson.
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    pt. 1. Theory -- pt. 2. Experiments -- pt. 3. Neutron Experiments.
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    v. 1. 1500 Multiple choice questions and referenced, selected explanatory answers; plus pretest and post-test examinations.
  • Three years after the publication of the first edition, Radiological Anatomy for FRCR Part 1 remains the best seller in its category based on its faithful representation of the examination. This second edition is designed to reflect the change in exam format introduced in spring 2013. It includes two new chapters as well as some new cases in the remaining chapters and tests. Under the new exam format, candidates will be presented with 100 cases, with a single question per case and a single mark for the correct answer. This book covers all core topics addressed by the exam in a series of tests and includes chapters focussing specifically on paediatric cases and normal anatomical variants. The answers to questions, along with explanations and tips, are supplied at the end of each chapter. Care has been taken throughout to simulate the exam itself. The book aims not to replace the already available literature on radiological anatomy but rather to complement it as a revision guide. It will help candidates to identify the level of anatomical knowledge expected by the Royal College of Radiologists.
  • This book, now in its second edition, provides a comprehensive analysis of imaging of the kidneys, upper urinary tract, and ureters, covering the normal anatomy and anatomic variants as well as all renal and urinary system pathologies. The relevant imaging modalities are first discussed, with detailed description of their applications in the kidney and upper urinary tract. The entire spectrum of kidney pathologies is then presented in a series of detailed chapters with up-to-date references, high-quality images, informative schemes, and figures showing macroscopic and microscopic surgical and pathologic specimens. Chapters relating to the latest innovations in tumor ablation, vascular and nonvascular interventional procedures, and parametric and molecular imaging have been fully updated to reflect progress in these rapidly evolving fields. This book will be of great interest to all radiologists, oncologists, nephrologists, and urologists who are involved in the management of kidney pathologies in their daily clinical practice.
  • Embryology and Anatomy of the Neonatal Chest / Stephanie Ryan -- Update on Clinical Management of Neonatal Chest Conditions / Anne Twomey -- Computed and Digital Radiography in Neonatal Chest Examination / Amaka C. Offiah -- Hyaline Membrane Disease and Complications of Its Treatment / Veronica Donoghue -- Transient Tachypnoea of the Newborn / Veronica Donoghue -- Meconium Aspiration / Catherine M. Owens -- Diagnostic Imaging of Neonatal Pneumonia / David Manson -- Antenatal Imaging of Chest Malformations / Laurent Garel -- Postnatal Imaging of Chest Malformations / Stephanie Ryan -- Congenital Anomalies of the Neonatal Upper Airway / David Manson -- Computed Tomography of the Central and Peripheral Airways / Alistair D. Calder and Catherine M. Owens -- Ultrasound of the Neonatal Thorax / Ingmar Gassner and Theresa E. Geley -- Ultrasound in Congenital Heart Disease / Colin J. McMahon and Benjamin W. Eidem -- Magnetic Resonance Imaging in Congenital Heart Disease / Christian J. Kellenberger -- Chest Radiography in Congenital Heart Disease / Bjarne Smevik -- Angiocardiography and Intervention in Congenital Heart and Great Vessel Disease / Bjarne Smevik and Per G. Bjørnstad -- Computed Tomography in Congenital Heart Disease / Laureen Sena and Hyun Woo Goo -- Chest Wall Abnormalities which Cause Neonatal Respiratory Distress / Georg F. Eich.
  • This book provides a state-of-the-art review of the technical and clinical aspects of the vascular interventional radiological (IR) procedures currently employed in obstetrics and gynaecology. A particular focus is on uterine artery embolisation for fibroid disease, which is contrasted with the main alternative uterus-conserving surgical approach of myomectomy, and with ablation therapy. Detailed consideration is also given to the role of embolisation in a variety of other less common conditions, including arteriovenous malformations, post-partum haemorrhage, abnormal placentation and pelvic congestion syndrome. IR procedures are examined from a critical gynaecological perspective and with regard to surgical alternatives. The authors include leading interventional radiologists and gynaecologists from the United Kingdom, Europe and North America. .
  • Radiological Safety and Quality - Paradigms in Leadership and Innovation is a multi-disciplinary and inter-sectorial collaboration by international experts and leaders from academic institutions, radiology practices, professional organizations, regulatory authorities, UN and international agencies. Established principles and new concepts, challenges and opportunities, and examples of leadership and innovations are discussed to raise awareness, share experience and facilitate development of facility-based or system-wide improvements in radiation safety, quality radiology, and patient care by procedure justification, optimization of protection and imaging data, and incident minimization. The 26 chapters by 53 experts and 11 messages from international organizations and agencies convey a common theme: there is no single panacea to improve radiological safety and quality but on-going leadership, innovation, collaboration, and stakeholder participation are needed.
  • Introduction -- Introduction / Antonio Zicca, Alberto Tagliafico -- Upper limb -- Shoulder / Erica Fisci, Alberto Tagliafico -- Elbow / Alberto Tagliafico, Carlo Martinoli -- Wrist / Alberto Tagliafico, Carlo Martinoli -- Lower limb -- Hip / Alberto Tagliafico, Erica Fisci, Carlo Martinoli -- Knee / Alberto Tagliafico, Carlo Martinoli -- Ankle / Bianca Bignotti, Carlo Martinoli, Alberto Tagliafico -- Spine -- Spine / Erica Fisci, Alberto Tagliafico
  • 1. Introduction -- 2. Diagnostic Imaging -- 3. Radiation Safety -- 4. X-rays and X-ray Tubes -- 5. Ultrasound -- 6. CT -- 7. MRI -- 8. Nuclear Medicine -- 9. Contrast Materials -- 10. Chest Overview -- 11. Cardiac -- 12. Abdomen -- 13. Acute Abdomen -- 14. Gastrointestinal Tract -- 15. Hepatobiliary System -- 16. Pancreas -- 17. Urinary Tract -- 18. Staging Cancer -- 19. Musculoskeletal -- 20. Severe Trauma Basics -- 21. Mammography -- 22. Interventional -- 23. Neuroradiology -- 24. Acute Care Chest -- 25. Midterm Quiz.
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    Radiography, computed tomography, magnetic resonance imaging, and ultrasonography: principles and indications / Willam E. Erkonen -- Chest / William E. Erkonen -- Abdomen / Edmund A. Franken Jr. -- Pediatric imaging / Wilbur L. Smith -- Musculoskeletal system / William E. Erkonen and Carol A. Boles -- Spine and pelvis / Carol A. Boles -- Brain / Wilbur L. Smith -- Head and neck / Yutaka Sato -- Nuclear imaging / David L. Bushnell -- Mammography / William E. Erkonen, Laurie L. Fajardo and John W. Boardman -- Interventional radiology / Thomas A. Farrell and Monte L. Harvill.
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    Radiography, computed tomography, magnetic resonance imaging, and ultrasonography : principles and indications / William E. Erkonen and Vincent A. Magnotta -- Chest / William E. Erkonen and Brad H. Thompson -- Abdomen / Edmund A. Franken, Jr. -- Pediatric imaging / Wilbur L. Smith -- Musculoskeletal system / William E. Erkonen and Carol A. Boles -- Spine and pelvis / Carol A. Boles --Brain / Wilbur L. Smith -- Head and neck / Yutaka Sato -- Nuclear imaging / David L. Bushnell, Jr. -- Breast imaging / Jeong Mi Park, William E. Erkonen, and Laurie L. Fajardo -- Interventional radiology / Thomas A. Farrell.
  • Part 1. Evaluation and Assessment for Non-educators -- The Nature of Professional Expertise / Penelope Engel-Hills and Rethy K. Chhem -- Fundamentals of Assessment and Evaluation: Clarifying Terminology / Kathryn M. Hibbert, Teresa Van Deven and Soveacha Ros -- Competence in the Professions: Expanding Opportunities and Emerging Practices / Kathryn M. Hibbert and Rethy K. Chhem -- Medical Competency in Postgraduate Medical Training Programs / Thomas N. B. Pascual, Soveacha Ros, Penelope Engel-Hills and Rethy K. Chhem -- Part 2. Evaluation and assessment in Radiology education -- Philosophical Considerations in Educational Assessment / Richard B. Gunderman -- Competencies and Experiential Requirements in Radiology Training / Shih-chang Wang -- Accreditation and Evaluation of Programs: The Canadian Perspective / Kenneth A. Harris, Margaret A. Kennedy and Sarah Taber -- Assessment and Evaluation in a Transnational Radiodiagnosis Training Program / Shih-chang Wang -- Part 3. Case Studies: Theory into practice -- Strategies and Actions to Improve Risk Communication Competency in Radiation Medicine / Lawrence S. Lau, Kwan-Hoong Ng and Rethy K. Chhem -- Assessing Clinical Competence in Radiation Oncology Education / Eduardo Rosenblatt, Bruce G. Haffty and Jan Willem Leer -- Measuring Competence of Radiology Education Programs and Residents: The Egyptian Experience / Sahar N. Saleem and Youssriah Y. Sabri -- Assessing Residents in a Nuclear Medicine Physician Training Program: The Philippine Experience / Thomas N. B. Pascual, Jerry M. Obaldo, Teofilo O. L. San Luis and Marcela J. Leus -- Clinical Training in Medical Physics: IAEA Perspective / Ahmed Meghzifene, Donald Mclean, Debbie Van Der Merwe and Brian Thomas -- Assessing Diagnostic Radiology Training: The Singapore Journey / Bien-Soo Tan, Lynette L. S. Teo, Daniel E. S. Wong, Shaun X. J. M. Chan and Kiang-Hiong Tay -- Assessment of Radiation Oncology Medical Physics Residents: The London, Ontario (Canada) Experience / Jacob Van Dyk and Jerry J. Battista.
  • Introduction: Transforming radiology education through scholarship -- The genesis and application of radiology education: mind the gap -- Scholarship in radiology education -- Today's radiology student: what every radiology training program director needs to know -- Teaching and learning: defining the scholarship of teaching -- Interdisciplinary learning: a stimulant for reflective practice -- Feedback in radiologic education -- The role of mentoring in professional education -- Radiological and biomedical knowledge integration: the ontological way -- Educational insights about professional ethics in radiology -- Learning in practice: new approaches to professional development for radiologists -- Acquiring competencies in radiology: the canMEDS model -- Technologies for teaching: exploring the use of PACS, databases, and teaching files -- Portable imaging systems for interactive teaching of radiography, computed tomography and ultrasound imaging principles -- Medical education research: challenges and opportunities in the scholarship of discovery -- Developing a radiology curriculum for a new medical school in Singapore -- Leadership in radiology education -- The business of radiology education scholarship -- Radiology education in Southeast Asia: current status and pedagogical challenges -- Training of ultrasound doctors and educational reform in West China hospital of Sichuan University, China -- Teaching radiology at the Angkor hospital for children in Siem Reap, Cambodia -- Teaching radiology in Latin America: images from Peru -- Using the world wide web to develop competencies around the globe -- The role of a learned society in promotion and dissemination of knowledge -- Radiology education in the faculty of medicine at Cairo University (Kasr Al-Ainy hospital).
  • Reading PET/CT scans is sometimes challenging. Not infrequently, abnormal findings on CT images are functionally silent and therefore difficult for nuclear medicine practitioners to interpret. Furthermore, in general only a low-dose CT scan is produced as part of the combined PET/CT study, and the resulting CT images may prove suboptimal for image interpretation. This atlas is designed to enable nuclear medicine practitioners who routinely read PET/CT scans to recognize the most common CT abnormalities. Slice-by-slice descriptions are provided of anatomical structures as visualized on CT scans obtained in PET/CT studies. The CT findings that may be detected while reviewing PET/CT scans of various body regions and conditions are then illustrated and fully described. The concluding section of the book is devoted to the principal MRI findings in diseases which cannot be evaluated using PETs/CTs.
  • This book is a concise introduction to the dynamic field of radiology and provides readers with general examples and brief discussions of basic radiographic principles. Introductory chapters present fundamental scientific concepts underlying the medical use of imaging modalities and technology, including ultrasound, computed tomography, magnetic resonance imaging, and nuclear medicine. Subsequent chapters are organized by anatomic region and imaging modality that highlight the radiologist?s role in diagnosing and treating common disorders. This revised edition is thoroughly updated and includes new or expanded chapters on nuclear medicine and pediatric radiology. Radiology Fundamentals, Fifth Edition, is a premier self-directed learning resource for medical students, non-radiology housestaff, physician assistants, nurse practitioners, radiologist assistants and other allied health professionals.
  • Part 1. Ultrasound and Transvaginal Ultrasound: Techniques, Normal Findings, and Variations. Introduction / Min Hoan Moon and Jung Sik Kim -- Illustrations / Min Hoan Moon and Jung Sik Kim -- pt. 2. Gynecologic CT and MRI: Techniques and Normal Findings. Introduction / Sung Il Jung and Bohyun Kim -- Illustrations / Sung Il Jung and Bohyun Kim -- pt. 3. Variations and Congenital Anomalies of the Female Genital Tract. Introduction / Jeong Kon Kim -- Illustrations / Jeong Kon Kim -- pt. 4. Uterine Myoma. Introduction / Byung Kwan Park -- Illustrations / Byung Kwan Park -- pt. 5. Adenomyosis. Introduction / Byung Kwan Park -- Illustrations / Byung Kwan Park -- pt. 6. Imaging Evaluation of Uterine Cervical Carcinoma. Introduction / Seung Hyup Kim and Kyung-Sik Cho -- Illustrations / Seung Hyup Kim and Kyung-Sik Cho -- pt. 7. Endometrial Cancer. Introduction / Sung Il Hwang and Seung Hyup Kim -- Illustrations / Sung Il Hwang and Seung Hyup Kim. pt. 8. Miscellaneous Tumors of the Uterus. Introduction / Yu Ri Shin and Sung Eun Rha -- Illustrations / Yu Ri Shin and Sung Eun Rha -- pt. 9. Post-treatment Changes and Recurrence of Uterine Malignancies. Introduction / Dae Chul Jung and Kie Hwan Kim -- Illustrations / Dae Chul Jung and Kie Hwan Kim -- pt. 10. Gestational Trophoblastic Diseases. Introduction / Jae Young Byun and Seung Eun Jung -- Illustrations / Jae Young Byun and Seung Eun Jung -- pt. 11. Miscellaneous Diseases of the Uterus. Introduction / Seung Eun Jung and Jae Young Byun -- Illustrations / Seung Eun Jung and Jae Young Byun -- pt. 12. Ovarian Cysts and Cystic Disease. Introduction / Hyuck Jae Choi -- Illustrations / Hyuck Jae Choi -- pt. 13. Ovarian Tumors: General Considerations and Mode of Spread. Introduction / Min Hoan Moon -- Illustrations / Min Hoan Moon -- pt. 14. Epithelial Tumors of the Ovary. Introduction / Sung Bin Park and Min Hoan Moon -- Illustrations / Sung Bin Park and Min Hoan Moon. pt. 15. Germ Cell Tumors of the Ovary. Introduction / Sun Ho Kim -- Illustrations / Sun Ho Kim -- pt. 16. Sex Cord-Stromal Tumors of the Ovary. Introduction / Jung Suk Sim -- Illustrations / Jung Suk Sim -- pt. 17. Miscellaneous Tumors of the Ovary and Adnexa. Introduction / Chang Kyu Sung and Jung Suk Sim -- Illustrations / Chang Kyu Sung and Jung Suk Sim -- pt. 18. Endometriosis. Introduction / Hyun Lee and Jeong Yeon Cho -- Illustrations / Hyun Lee and Jeong Yeon Cho -- pt. 19. Adnexal Torsion. Introduction / Sung Eun Rha and Young-Hwa Kim -- Illustrations / Sung Eun Rha and Young-Hwa Kim -- pt. 20. Pelvic Inflammatory Disease and Tubo-ovarian Abscess. Introduction / Jeong Yeon Cho -- Illustrations / Jeong Yeon Cho -- pt. 21. Ectopic Pregnancy. Introduction / Min Hoan Moon and Young-Ho Lee -- Illustrations / Min Hoan Moon and Young-Ho Lee. pt. 22. Vagina and Vulva. Introduction / Sun Ho Kim and Bohyun Kim -- Illustrations / Sun Ho Kim and Bohyun Kim -- pt. 23. Vascular Diseases of the Female Pelvis. Introduction / Seong Jin Park -- Illustrations / Seong Jin Park -- pt. 24. Pediatric Gynecologic Diseases. / Introduction / So-Young Yoo and Woo Sun Kim -- Illustrations / So-Young Yoo and Woo Sun Kim -- pt. 25. Nongynecologic Lesions Mimicking Gynecologic Diseases. Introduction / Bum Sang Cho and Seung Hyup Kim -- Illustrations / Bum Sang Cho and Seung Hyup Kim -- pt. 26. Hysterosalpingography. Introduction / Hak Jong Lee -- Illustrations / Hak Jong Lee -- pt. 27. Sonohysterography. Introduction / Eun Ju Lee -- Illustrations / Eun Ju Lee -- pt. 28. Gynecologic Nonvascular Interventions. Introduction / See Hyung Kim and Seung Hyup Kim -- Illustrations / See Hyung Kim and Seung Hyup Kim -- pt. 29. Obstetric and Gynecologic Vascular Interventions. Introduction / Man-Deuk Kim and Jin Wook Chung -- Illustrations.
  • Illustrates how to achieve reliable diagnoses when confronted by the different abnormalities, or disease patterns, that may be visualized on CT scans of the chest.
  • Part 1. Pharynx/Esophagus -- 1. Benign structural and functional abnormality of the esophagus, postop. Complication of the esophagus -- 2. Esophagitis -- 3. Benign and malignant tumor of the esophagus -- Part 2. Stomach/Duodenum -- 4. Benign structural & functional abnormality of the stomach and duodenum -- 5. Inflammatory and infectious diseases of the stomach and duodenum -- 6. Mucosal tumor of the stomach -- 7. Subepithelial tumor of the stomach -- 8. Lymphoma and metastasis of the stomach -- 9. Postoperative change and complications of the stomach and duodenum -- Part 3. Small Bowel -- 10. Benign structural & functional abnormality of the small bowel -- 11. Inflammatory disease of the small bowel -- 12. Vasculitis and ischemic bowel disease -- 13. Small bowel obstruction -- 14. Benign tumor of the small bowel -- 15. Malignant tumor of the small bowel -- Part 4. Colon -- 16. Benign structural & functional abnormality of the colon -- 17. Inflammatory & infectious disease of the colon -- 18. Benign tumor of the colon -- 19. Malignant tumor of the colon -- 20. Postoperative change and complications of the colon -- Part 5. Mesentery, Peritoneum, abdominal wall -- 21. Benign diseases of mesentery and omentum -- 22. Malignant diseases of mesentery and omentum -- 23. Abdominal wall abnormality & hernia.
  • Radiology Illustrated: Hepatobiliary and Pancreatic Radiology is the first of two volumes that will serve as a clear, practical guide to the diagnostic imaging of abdominal diseases. This volume, devoted to diseases of the liver, biliary tree, gallbladder, pancreas, and spleen, covers congenital disorders, vascular diseases, benign and malignant tumors, and infectious conditions. Liver transplantation, evaluation of the therapeutic response of hepatocellular carcinoma, trauma, and post-treatment complications are also addressed. The book presents approximately 560 cases with more than 2100 carefully selected and categorized illustrations, along with key text messages and tables, that will allow the reader easily to recall the relevant images as an aid to differential diagnosis. At the end of each text message, key points are summarized to facilitate rapid review and learning. In addition, brief descriptions of each clinical problem are provided, followed by both common and uncommon case studies that illustrate the role of different imaging modalities, such as ultrasound, radiography, CT, and MRI.
  • This case-based atlas presents images depicting the findings typically observed when imaging a variety of common and uncommon diseases in the pediatric age group. The cases are organized according to anatomic region, covering disorders of the brain, spinal cord, head and neck, chest, cardiovascular system, gastrointestinal system, genitourinary system, and musculoskeletal system. Cases are presented in a form resembling teaching files, and the images are accompanied by concise informative text. The goal is to provide a diagnostic reference suitable for use in daily routine by both practicing radiologists and radiology residents or fellows. The atlas will also serve as a teaching aide and a study resource, and will offer pediatricians and surgeons guidance on the clinical applications of pediatric imaging.
  • Radiology Illustrated: Spine is an up-to-date, superbly illustrated reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. Common, critical, and rare but distinctive spinal disorders are described succinctly with the aid of images highlighting important features and informative schematic illustrations. The first part of the book, on common spinal disorders, is for radiology residents and other clinicians who are embarking on the interpretation of spinal images. A range of key disorders are then presented, including infectious spondylitis, cervical trauma, spinal cord disorders, spinal tumors, congenital disorders, uncommon degenerative disorders, inflammatory arthritides, and vascular malformations. The third part is devoted to rare but clinically significant spinal disorders with characteristic imaging features, and the book closes by presenting practical tips that will assist in the interpretation of confusing cases.
  • Uroradiology is an up-to-date, image-oriented reference in the style of a teaching file that has been designed specifically to be of value in clinical practice. All aspects of the imaging of urologic diseases are covered, and case studies illustrate the findings obtained with the relevant imaging modalities in both common and uncommon conditions. Most chapters focus on a particular clinical problem, but normal findings, congenital anomalies, and interventions are also discussed and illustrated.In this second edition, the range and quality of the illustrations have been enhanced, and many schematic drawings have been added to help readers memorize characteristic imaging findings through pattern recognition. The accompanying text is concise and informative. Besides serving as an outstanding aid to differential diagnosis, this book will provide a user-friendly review tool for certification or recertification in radiology.
  • "The only book of its kind to prepare radiology residents interested in working on global health service projects in the developing world Includes information on designing, testing, and deploying clinical strategies adapted for regions with limited resources Presents information technology models to support digital imaging in the developing world This book is designed to increase awareness of the global health problem of lack of access to medical imaging services and presents solutions to overcome disparities in the delivery of radiologic services to the developing world. Featuring an interdisciplinary framework, it discusses economic strategies for sustainable radiology; public health radiology for population-based approaches; clinical model formulation tailored to needs and resources of regions and communities; technology innovation and optimization; and public policy for healthcare system development at the government and international institutional level. It explores the role of radiology in addressing health care disparities and highlights strategies for radiology services planning and implementation in low resource settings. It also provides an overview of the clinical role of medical imaging in the developing world, including epidemiology, disaster response, and specific clinical applications for recognizing and managing illnesses unique to the developing world. Radiology in Global Health: Strategies, Implementation, and Applications examines ways to achieve sustainable long-term imaging strategies for limited resource regions and is a valuable resource for radiologists, radiology residents, radiology technologists, physicians, nurses, and healthcare administrators"--Provided by publisher.
  • Concise, systematic atlas to thoracic radiology emphasizing computed tomography. Includes a new chapter on cardiac imaging. For practitioners. Translated from the 3rd German edition: Radiologische Diagnostik der Thoraxerkrankungen, c2005. Halftone and color images and illustrations.
  • Molecular Biology of HIV/AIDS and Its Clinical Management -- An Overview of Clinical Immunology of HIV/AIDS -- An Overview of Clinical Microbiology of HIV/AIDS -- Epidemiological Investigation of AIDS -- Pathogenetic and Pathological Mechanism -- Clinical Manifestations of HIV/AIDS Infection -- Laboratory Test and Special Examinations -- Diagnostic Imaging -- AIDS Imaging and Evidence Based Medicine -- Clinical Medication Against HIV/AIDS -- Introduction to Assessment and Monitoring of Critical AIDS -- HIV Related Effect Factors -- HIV/AIDS Related Nervous System Diseases -- HIV/AIDS Related Myeleterosisand Peripheral Neuropathy -- HIV/AIDS Related Eye Diseases -- HIV/AIDS Related Neck Diseases -- HIV/AIDS Related Respiratory Diseases -- HIV/AIDS Related Cardiac Diseases -- HIV/AIDS Related Gastrointestinal Diseases -- HIV/AIDS Related Hepatobiliary, Pancreatic and Splenic Diseases -- HIV/AIDS Related Peritoneal and Retroperitoneal Disease -- HIV/AIDS Related Urogenital Disease -- HIV/AIDS Related Musculoskeletal Diseases -- HIV/AIDS Related Pediatric Diseases -- HIV/AIDS Related Skin Diseases -- Functional Imaging of HIV/AIDS.
  • A novel strain of influenza A (H1N1) virus emerged and an outbreak of influenza A (H1N1) occurred worldwide in 2009 and 2010, posing a severe threat to the health of human beings. The two Editors work together in Beijing You An Hospital, to combat this type of influenza. This book, Radiology of Influenza A (H1N1), is intended to provide first-hand clinical data and its scientific analysis, thus supporting sound clinical practice for influenza A (H1N1) prevention and treatment as well as related scientific research. The authors have collected over 100 critical influenza A (H1N1) virus-infected cases. For cases of influenza A (H1N1) that resulted in death, autopsies were performed for 8 cases after receiving their families' informed consent. Over 200 reports on pathological and histological analysis as well as immunohistochemical and electroscopic analysis were brought together. This book was then compiled by comparing the published data with the present first-hand data. This book includes a wealth of content, including DR, CT and MRI images, pathological and histological figures, and immunohistochemical and electroscopic figures. Related research, clinical and educational needs can be readily satisfied by its detailed data, texts and figures, as well as typical case reports. Li Hongjun, is professor and director of the diagnostic radiology department in Beijing You An Hospital, affiliated with Capital Medical University, Beijing, China. Li Ning, is professor and president of Beijing You An Hospital, affiliated with Capital Medical University, Beijing, China.
  • Introduction to radiology -- Head and neck -- Thorax -- Abdomen -- Pelvis -- Extremities: general overview -- Upper extremity -- Lower extremity.
  • "Dr. Jonathan J. Dutton, a world leader in orbital surgery, presents Radiology of the Orbit and Visual Pathways. This new and unique diagnostic guide offers expert advice on the full spectrum of uses of CT and MRI, the two core methods of radiologic imaging of the orbit. An atlas style approach provides the essential text you need to accurately diagnose over 120 of the more common disorders you'll come across in your daily routine, and over 1,100 lavish illustrations enhance your visual guidance. Covering the entire visual pathways from the eye to the occipital cortex, you'll gain thorough knowledge of normal anatomy and how it compares to pathologic findings to confidently diagnose. Plus, with Expert Consult functionality, you'll have easy access to the full text online, as well as all of the book's illustrations at expertconsult.com."--Publisher's website.
  • Introduction to the Post Surgical Abdomen / Alan G. Chalmers, David Macafee, Damian J. M. Tolan and John Brittenden -- The Esophagus / Damian J. M. Tolan, Keith M. Harris, Deepak Prasad and Samir P. Mehta -- The Stomach and Duodenum / Damian J. M. Tolan, Keith M. Harris, Deepak Prasad and Samir P. Mehta -- The Pancreas / Krishna Menon, John Brittenden, Simon McPherson, Nikhil M. Bhuskute and Andrew Smith -- The Biliary Tree / Vamshi P. Jagadesham, Maria Sheridan, J. Peter A. Lodge and John Brittenden -- The Liver / J. Ashley Guthrie, Hajamohideen M. Salahudeen and J. Peter A. Lodge -- The Small Bowel / James C. Lenton, Adeshina S. Fawole, John Brittenden and Damian J. M. Tolan -- The Colon / Chris Macklin, John Brittenden, David Jayne and Damian J. M. Tolan -- Genitourinary System / Christopher Wilkinson.
  • "The book describes the disease entities, radiologic symptoms., as well as lists of differential diagnosis"--Provided by publisher.
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  • Musculoskeletal radiology -- Chest radiology -- Gastrointestinal radiology -- Genitourinary radiology -- Head and neck radiology -- Vascular and interventional -- Nuclear medicine -- Ultrasound -- Pediatrics -- Breast -- Neuroradiology.
  • This atlas fills a gap in the literature by documenting in detail the role of nuclear medicine imaging of infection and inflammation. The pathophysiologic and molecular mechanisms on which radionuclide imaging of infection/inflammation is based are clearly explained, but the prime focus of the book is on the clinical relevance of such procedures. Their impact is demonstrated by a collection of richly illustrated teaching cases that describe the most commonly observed scintigraphic patterns, as well as anatomic variants and technical pitfalls. Due attention is paid to the application of recently developed techniques, including multimodality fusion imaging such as SPECT/CT and PET/CT. Emphasis is placed in particular on the ability of multimodality imaging to increase both the sensitivity and the specificity of radionuclide imaging. This atlas will be an excellent learning tool for residents in nuclear medicine and illuminating for other specialists with an interest in the field. Learning tool especially useful for residents in nuclear medicine and for specialists in nuclear medicine approaching the field. Useful integration for residents and for specialists also in infectious and autoimmune diseases, as well as in orthopedics.
  • "This comprehensive overview details the process of radiopharmaceutical development, from cellular studies to animal experiments to the design and implementation of clinical trials. It examines the relative benefits of various radiopharmaceuticals and provides guidance on dose estimation and agent selection. Utilizing figures of merit for quantitative assessment, it covers standard medical internal radiation dose (MIRD), absorbed dose method for imaging agents, vivo methods for obtaining activity data, errors of activity estimation techniques, phantom-based and patient-based dose estimates and their associated uncertainties, and options available to clinical physicists. Supported by numerous examples from clinical trials, it discusses two and three dimensional estimation processes, including modern hybrid scanners such as SPECT/CT and PET/CT"--Provided by publisher.
  • Imaging, delineation and immobilization: MRI and MR-spectroscopy -- PET imaging in prostate cancer -- Phase contrast X-ray imaging- next generation CT imaging -- Organ contouring for IMRT -- General aspects of patient immobilization -- Internal immobilization: From rectal balloon to hyaluronic acid -- Clinical endpoints: Biochemical recurrence? a valuable endpoint? -- Overall and disease-free survival ? too long to wait? -- Late toxicity ? current scoring concepts -- Quality of life: Assessment and Correlates -- Dose escalation and new radiation techniques: Dose escalation ? an update on randomized clinical trials -- IMRT for prostate cancer -- IGRT- how and when -- Tracking in prostate cancer -- Locally advanced disease: Techniques of pelvic lymphatic irradiation -- Prophylactic treatment of the pelvic lymphatics: pro -- Prophylactic treatment of the pelvic lymphatics: contra -- Hormonal therapy and radiation therapy -- randomized and prospective trials -- Treatment of clinically involved lymph nodes -- Hypofractionation: Hypofractionation in prostate cancer- biological aspects -- Hypofractionation: Clinical data -- Simultaneous integrated boost techniques -- Brachytherapy: Principals of 3D, highly conformal brachytherapy -- Seed implantation -- HDR brachytherapy -- Adjuvant treatment and salvage treatment: Target volume definition in postoperative radiotherapy -- Randomized trials for adjuvant radiotherapy -- Salvage radiotherapy after radical prostatectomy -- Salvage prostatectomy after radiotherapy -- Use of protons and heavy ions: Proton therapy for prostate cancer: technological and clinical aspects -- There is evidence for the superiority of protons or heavy ions, pro -- There is evidence for the superiority of protons or heavy ions, contra. .
  • Radiotracers and drug registration -- Radioactivity and radiotracers -- The study of drug metabolism using radiotracers -- DNA binding, isotope dilution and other uses of radiotracers -- Quantitative whole-body autoradiography (QWBA) -- Scintillation counting -- Statistics in liquid scintillation counting -- Instrumentation for detection of radioactivity -- Sample preparation for liquid scintillation counting -- Biomedical accelerator mass spectrometry -- Positron emission tomography -- Gamma scintigraphy and SPECT.
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  • Radial Forearm Flap -- Lateral Arm Flap -- Anterolateral Thigh / Vastus Lateralis Flap -- Latissimus Dorsi Flap -- Scapular Flap -- Fibular Flap -- Klaus-Dietrich Wolff and Frank Hölzle -- Iliac Crest Bone Flap -- Perforator Flaps -- Anterolateral Thigh Perforator Flap -- Soleus Perforator Flap -- Deep Inferior Epigastric Artery Perforator Flap.
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  • Introduction and scope -- Magnitude of Raman scattering -- Collection and detection of Raman scattering -- Signal-to-noise in Raman spectroscopy -- Instrumentation overview and spectrometer performance -- Sampling modes in Raman spectroscopy -- Lasers for Roman spectroscopy -- Dispersive Raman spectrometers -- Nondispersive Raman spectrometers -- Calibration and validation -- Raman microscopy and imaging -- Fiber-optic Raman sampling -- Raman spectroscopy of surfaces.
  • "Nonpharmacological treatments include a wide variety of treatments such as surgery, technical procedures, implantable devices, nonimplantable devices, rehabilitation, psychoteherapy, and behavioral interventions. This book focuses on the methods of assessing nonpharmacological treatments, highlighting specific issues and discussing all possible design of trials. It provides practical examples to underline the issues and solutions in assessing nonpharmacological treatment in trials. Arguably the first book to exclusively explore this topic, it discusses various categories of treatments from surgical procedures to psychotherapy"--Provided by publisher.
  • In cancer research, a traditional phase II trial is designed as a single-arm trial that compares the experimental therapy to a historical control. This simple trial design has led to several adverse issues, including increased false positivity of phase II trial results and negative phase III trials. To rectify these problems, oncologists and biostatisticians have begun to use a randomized phase II trial that compares an experimental therapy with a prospective control therapy.
  • What is pharmacology? -- How drugs act : general principles -- How drugs act : molecular aspects -- How drugs act : cellular aspects, excitation, contraction and secretion -- Cell proliferation, apoptosis, repair and regeneration -- Cellular mechanisms : host defence -- Method and measurement in pharmacology -- Absorption and distribution of drugs -- Drug metabolism and elimination -- Pharmacokinetics -- Individual variation, pharmacogenomics and personalised medicine -- Chemical mediators and the autonomic nervous system -- Cholinergic transmission -- Noradrenergic transmission -- 5-Hydroxytryptamine and the pharmacology of migraine -- Purines -- Local hormones 1 : histamine and the biologically active lipids -- Local hormones 2 : peptides and proteins -- Cannabinoids -- Nitric oxide and related mediators -- The heart -- The vascular system -- Atherosclerosis and lipoprotein metabolism -- Haemostasis and thrombosis -- Haemopoietic system and treatment of anaemia -- Anti-inflammatory and immunosuppressant drugs -- Skin -- Respiratory system -- The kidney and urinary system -- The gastrointestinal tract -- The control of blood glucose and drug treatment of diabetes mellitus -- Obesity -- The pituitary and the adrenal cortex -- The thyroid -- The reproductive system -- Bone metabolism -- Chemical transmission and drug action in the central nervous system -- Amino acid transmitters -- Other transmitters and modulators -- Neurodegenerative diseases -- General anaesthetic agents -- Analgesic drugs -- Local anaesthetics and other drugs affecting sodium channels -- Anxiolytic and hypnotic drugs -- Antiepileptic drugs -- Antipsychotic drugs -- Antidepressant drugs -- CNS stimulants and psychotomimetic drugs -- Drug addiction, dependence and abuse -- Basic principles of antimicrobial chemotherapy -- Antibacterial drugs -- Antiviral drugs -- Antifungal drugs -- Antiprotozoal drugs -- Anthelmintic drugs -- Anticancer drugs -- Harmful effects of drugs -- Lifestyle drugs and drugs in sport -- Biopharmaceuticals and gene therapy -- Drug discovery and development.
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  • This volume provides practitioners with a practical, easy to read, well organized approach to the performance and analysis of urodynamics in order to optimize their usage clinically. Chapters are structured around specific types of patterns seen on urodynamic tracings. These urodynamic tracings are annotated and fully interpreted by the authors. Multiple examples of each type of tracing are provided with expert commentary. The expert commentary expands on the potential clinical significance of the tracing, provides a differential diagnosis, and, where appropriate, discusses its importance diagnostically, prognostically and the implications for clinical management. The text contains chapters on virtually all the relevant urodynamic findings and clinical conditions seen in practice, including lower urinary tract conditions in both adults and children, neurogenic and non-neurogenic dysfunction, and other commonly seen conditions such as lower urinary tract obstruction, vaginal prolapse, and detrusor overactivity. The material is also presented in a practical manner, with special consideration to the latest national and international guidelines. Written by authorities in the field, Rapid and Practical Interpretation of Urodynamics is a valuable resource that fills a key gap by providing a systematic method of interpretation of urodynamic tracings in an easy to understand textbook that will benefit urologic trainees and experienced urologists alike.
  • The Rapids are a series of reference and revision pocket books that cover key facts in a simple and memorable way. Each book contains the common conditions that students and newly qualified nurses encounter on the wards, in the community, and on placements. Only the basic core relevant facts are provided to ensure that these books are perfect and concise rapid refreshers. Rapid Infection Control Nursing is an essential read for all frontline nursing staff working in hospitals or community settings. Designed for quick reference, it explores the essential principles of infection.
  • Neurology -- Ophthalmology -- Otorhinolaryngology -- Pulmonology -- Cardiology -- Gastroenterology -- Psychiatry -- Rheumatology -- Orthopedics -- Dermatology -- Endocrinology -- Urology -- Obstetrics and gynecology -- Hematology and oncology -- Preventive medicine and misc topics -- Emergency medicine -- Pediatrics -- Surgery -- Radiology -- Infectious disease.
  • Laboratory test interpretation -- Electrolyte and acid-base disorders -- Pulmonary function tests -- Renal function tests -- Red blood cell disorders -- White blood cell disorders -- Hemostasis disorders -- Immunohematology -- Clinical chemistry -- Endocrine testing -- Body fluid analysis -- Clinical immunopathology.
  • "Get the most from your study time, and experience a realistic USMLE simulation with Rapid Review Microbiology and Immunology, 3rd Edition, by Drs. Ken S. Rosenthal and Michael J. Tan. This new reference in the highly rated Rapid Review Series is formatted as a bulleted outline with photographs, tables and figures that address all the microbiology and immunology information you need to know for the USMLE. And with Student Consult functionality, you can become familiar with the look and feel of the actual exam by taking a timed or a practice test online that includes 400 USMLE-style questions."--Publisher's website.
  • This book is by Edward F. Goljan, MD, makes it easy for you to master all of the pathology material covered on the USMLE Steps 1 and 2. It combines an updated outline-format review of key concepts and hundreds of full-color images and margin notes, PLUS more than 400 USMLE-style online questions! Get all the practice you need to succeed on the USMLEs! New to this edition: Visualize key pathologic concepts and conditions with over 1,000 full-color images, completely reviewed and updated for this new edition.
  • 1. Pharmacokinetics -- 2. Pharmacodynamics -- 3. Introduction to Autonomic and Neuromuscular Pharmacology -- 4. Cholinergic Drugs -- 5. Adrenergic Drugs -- 6. Muscle Relaxants -- 7. CNS Introduction, and Sedative-Hypnotic and Anxiolytic Drugs -- 8. Anesthetics -- 9. Anticonvulsant Drugs -- 10. Psychotherapeutic Drugs -- 11. Drugs Used in the Treatment of Parkinson's Disease -- 12. Antiarrhythmic Drugs -- 13. Antihypertensive Drugs -- 14. Other Cardiovascular Drugs -- 15. Diuretics -- 16. Drugs Used in the Treatment of Coagulation Disorders -- 17. Hematopoietic Drugs -- 18. Nonsteroidal Anti-Inflammatory Drugs and other Nonopioid Analgesic-Antipyretic Drugs -- 19. Opioid Analgesics and Antagonists -- 20. Drugs Used in the Treatment of Asthma, Chronic Obstructive Pulmonary Disease and Allergies -- 21. Drugs Used in the Treatment of Gastrointestinal Disorders -- 22. Immunosuppressive Drugs and Drugs Used in the Treatment of Rheumatic Disorders and Gout -- 23. Drugs Used in the Treatment of Hypothalamic, Pituitary, Thyroid, and Adrenal Disorders -- 24. Drugs Used in the Treatment of Diabetes Mellitus and Errors of Glucose Metabolism -- 25. Drugs Used in the Treatment of Bone and Calcium Disorders -- 26. Drugs Used in Reproductive Endocrinology -- 27. Antimicrobial Drugs -- 28. Other Anti-Infective Drugs -- 29. Chemotherapeutic Drugs -- 30. Toxicology and Drugs of Abuse Common Laboratory Values.
  • Get the most from your study time, and experience a realistic USMLE simulation, 2nd Edition, by Dr. Thomas A. Brown. This new reference in the highly rated Rapid Review Series is formatted as a bulleted outline with clinical images, tables and figures that make it easy to review all the physiology information you need to know for the USMLE. And with Student Consult online access, you can become familiar with the look and feel of the actual exam by taking a timed or a practice online test that includes 350 USMLE-style questions. Review the most current information with completely updated chapters, images, and questions. Profit from the guidance of series editor Dr. Edward Goljan, a well-known author of medical review books, who reviewed and edited every question. Study and take notes more easily with the new, larger page size. This edition thoroughly updated, including student and resident reviewer feedback to ensure relevancy and focus. Practice with a new testing platform on the USMLE Consult testing engine that gives you a realistic review experience and fully prepares you for the exam.
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    [1] Diagnostic et traitement des hémorragies digestives aiguës / par Fr. Moyson et A. de Scoville avec la collaboration de S. Godart ... [et al.].
  • Epidemiology and databases -- Rare and uncommon gynecological cancers: a clinical guide -- The contribution of diagnostic imaging in rare gynecological malignancies -- Mucinous cancers: ovary -- Pseudomyxoma peritonei -- Ovarian clear cell carcinoma -- Clear cell carcinoma of the ovary -- The continuum of serious ovarian tumors of low malignant potential and low-grade serous carcinoma of the ovary -- Sex cord-stromal tumors -- Squamous cell carcinomas arising from dermoids -- Ovarian carcinosarcomas -- Small cell and neuroendocrine cancers of the ovary -- Primary ovarian carcinoids and neuro-endocrine tumors including struma ovarii -- Reed uterine carcinosarcomas -- Leiomyosarcomas of uterus -- Mucinous tumors of the uterine corpus -- Clear cell cancers of uterus -- Small cell and neuroendocrine cancers of the cervix -- Primary malignant melanoma of the vulva and vagina -- Gynecologic cancers in pregnancy: guidelines of an international consensus meeting.
  • Rare diseases-avoiding misperceptions and establishing realities : the need for reliable epidemiological data / Stephen C. Groft and Manuel Posada de la Paz -- Rare diseases epidemiology research / Manuel Posada de la Paz ... [et al.] -- Evidence-based medicine and rare diseases / Simon Day -- Prevention, diagnosis, and services / Eva Bermejo and María Luisa Martínez-Frías -- The importance of case reports in advancing scientific knowledge of rare diseases / John C. Carey -- Patient registries : utility, validity, and inference / Rachel Richesson and Kendra Vehik -- Biobanking in rare disorders / Hanns Lochmüller and Peter Schneiderat -- Evaluation of the validity and utility of genetic testing for rare diseases / Scott D. Grosse, Lisa Kalman, and Muin J. Khoury -- Population-based surveillance for rare congenital and inherited disorders : models and challenges / Jodi M. Jackson, Krista S. Crider, and Richard S. Olney -- Statistical methods for the geographical analysis of rare diseases / Virgilio Gómez-Rubio and Antonio López-Quílez -- Clinical trials and rare diseases / Joachim Werner Otto Gerss and Wolfgang Köpcke -- A regulatory overview about rare diseases / Jordi Llinares -- Economic considerations in the provision of treatments for rare diseases / Christopher McCabe, Richard Edlin, and Jeff Round -- Rare diseases social epidemiology : analysis of inequalities / Anna Kole and François Faurisson -- Quality of life and rare diseases / Luis Rajmil, Lilisbeth Perestelo-Pérez, and Michael Herdman -- Cost of illness and economic evaluation in rare diseases / Julio López-Bastida and Juan Oliva-Moreno -- The burden of rare cancers in Europe / Gemma Gatta ... [et al.] -- Hereditary channelopathies in neurology / Karin Jurkat-Rott ... [et al.] -- Osteochondral diseases and fibrodysplasia ossificans progressiva / Antonio Morales-Piga and Frederick S. Kaplan -- The prevalence of congenital anomalies in Europe / Helen Dolk, Maria Loane, and Ester Garne -- Rare autoimmune diseases / Arrigo Schieppati and Erica Daina -- Epidemiology of rare anaemias in Europe / Beatrice Gulbis ... [et al.] -- Inherited metabolic rare disease / Teresa Pampols -- The contribution of rare diseases to understanding the epidemiology of neurodevelopmental disabilities / Diana Schendel, Catherine Rice, and Christopher Cunniff -- Creating a European Union framework for actions in the field of rare diseases / Antoni Montserrat Moliner -- National plans and strategies on rare diseases in Europe / Domenica Taruscio, Luciano Vittozzi, and Rumen Stefanov -- Ethical aspects on rare diseases / Luis A. Barrera and Gilberto Cely Galindo -- Advocacy groups and their role in rare diseases research / Mary Dunkle, Wayne Pines, and Peter L. Saltonstall.
  • This book focuses on predictive, preventative and personalised medicine (PPPM) and how it is related to the healthcare of rare diseases. Readers will discover how advanced rare diseases healthcare provides an excellent "proof-of-principles" for the personalisation of healthcare systems on a global scale. Chapters look at national plans for rare disease, at biobanking, gene identification, rare cancers, virus gene therapy, induced pluripotency for cell therapy amongst other topics. There is a chapter dedicated to personalised medicine for hereditary deafness, and another exploring the complexity of genotype-phenotype correlations. Specific diseases such as Fabry's, Gauchers and mitochondrial cytopathies are highlighted and we look at enzyme replacement therapy in lysosomal storage diseases. This work is part of a series, produced with the involvement of the European Association for Predictive, Preventive and Personalised Medicine. The series focusses on the concept of an integrative medical approach by PPPM. This volume is dedicated to all aspects related to the prediction, prevention and personalised treatments of rare diseases, and in doing so it explores developments relevant to all medical branches. The authors cover ethical considerations, the creation of a robust platform for professional communication, synergies with patient organisations, "doctor-patient" collaboration and a new philosophy of integrative medicine by PPPM. This volume serves as a reference source for scientific and medical centres in the field and can be used both at medical curricula and graduate level in the life sciences. Those who place a special emphasis on healthcare promotion and innovations intended to combat rare diseases, save the affected lives and enhance life quality will all find this book of great value.
  • Rare lymphomas 2014
    Springer
    The past decade has witnessed tremendous progress in the diagnostic and therapeutic approaches to malignant lymphoma as well as in understanding of the underlying molecular pathogenesis. Optimal treatment strategies are now based not only on accurate diagnosis but also on thorough evaluation of clinical and molecular risk factors. Even more importantly, molecular targeted approaches have been shown to be effective in the treatment of distinct lymphoma subtypes. Against this background, clinical management of especially the rare lymphomas remains a challenge for the general oncologist. This book provides a comprehensive overview of current treatment strategies in these rare lymphoma subtypes. Experts in the field from around the world describe the histomorphology in a clinically relevant manner, consider the role of risk factors in detail, and discuss the spectrum of therapeutic approaches. Special emphasis is placed on the translation of molecular science into clinical care, and a disease-specific algorithm is proposed for each entity. This book will prove an excellent resource for both experienced and inexperienced practitioners.
  • This book provides practitioners with a single volume that reviews the clinical and pathologic features of rarely encountered cutaneous neoplasms. The text includes an in-depth discussion of the clinical findings, as well as the histologic and immunologic features of these diseases that are rarely encountered, reported, or recognized. Additional laboratory data used to make and support the diagnoses with some therapeutic and prognostic hints are discussed for each entity. The volume is organized into general categories correlating with the cell(s) of origin. An atlas of clinical manifestations is presented for each entity that will serve as a bedside clinical reference, followed by a series of photomicrographs depicting the histologic changes. In all cases, recent updates on molecular tools helpful in attaining the diagnosis are added to the sections on histology and immunohistochemistry. Rare Malignant Skin Tumors is a valuable bedside reference for the practicing dermatopathologist, general pathologist reviewing skin biopsies, general dermatologists, cutaneous oncologists and Mohs? surgeons.
  • This is the first book to be devoted exclusively to rare tumors in children and adolescents, and its aim is to provide up-to-date information on their diagnosis and clinical management. The opening section of the book addresses general issues including epidemiology, risk factors/etiology, biology and genetics, prevention, early detection, and screening. It also discusses solutions to assist in the management of rare tumors, such as international networking and internet platforms, thus providing the reader with access to the developing clinical network for rare tumors in children. In the second section, specific malignancies are described, with practical guidance on diagnostic workup, multimodal therapy, survival outcome, follow-up, and adverse effects. These chapters are organized by site according to the clinician{u2019}s approach to the patient. Each chapter includes an introduction to the differential diagnostic assessment of tumors at the site in question, encompassing both frequent and rare tumor types. This approach should enable the clinician to take rare entities into account during the diagnostic assessment, so that the initial diagnostic steps are performed optimally. Each chapter goes on to provide detailed therapeutic guidelines for specific rare tumors. The authors are a multidisciplinary group of specialists who have dedicated themselves to this group of tumors. This well-illustrated book will prove an invaluable source of information for all pediatricians and oncologists faced with the often difficult task of diagnosing and treating rare tumors in the pediatric age group.
  • RAS family GTPases 2006
    Springer
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  • Machine generated contents note: 1 Anatomical Differences in the Peripheral Auditory System of Mammals and Man -- Felix, H. (Zfirich) -- 11 Neurotransmission in the Human Labyrinth -- Schrott-Fischer, A.; Kammen-Jolly, K.; Scholtz, A.W. (Innsbruck); -- Kong, W.-J. (Hua-Zhong); Eybalin, M. (Montpellier) -- 18 Different Action of Memantine and Caroverine on Glutamatergic Transmission in the Mammalian Cochlea -- Oestreicher, E. (Munich/Berne); Ehrenberger, K. (Vienna); Felix, D. (Berne) -- 26 Role of Substance P in the PeripheralVestibular and Auditory System -- Felix, H. (Zirich); Oestreicher, E. (Munich/Berne); Felix, D. (Berne); -- Ehrenberger, K. (Vienna) -- Hair Cells - Ion Channels -- 35 Calcium Channels in Mouse Hair Cells: Function, Properties and Pharmacology -- Engel, J.; Michna, M. (Tiibingen); Platzer, J.; Striessnig, J. (Innsbruck) -- 42 Adrenergic and Muscarinic Control of Cochlear Endolymph Production -- Wangemann, P. (Manhattan) -- 51 Cochlear Blood Flow Regulation -- Wangemann, P. (Manhattan) -- 58 ETA Receptors in the Gerbil Spiral Modiolar Artery -- Scherer, E.Q.; Wangemann, P. (Manhattan) -- Immunology - Cell Cycle -- 66 Immunological Damage to the Inner Ear: Current and Future Therapeutic Strategies -- Ryan, A.F. (San Diego/La Jolla); Pak, K.; Low, W; Battaglia, A.; Mullen, L.; -- Harris, J.P.; Keithley, E.M. (San Diego) -- 75 Pharmacological Influence on Inner Ear Endothelial Cells in Relation to the Pathogenesis of Sensorineural Hearing Loss -- Gloddek, B.; Lamm, K.; Arnold, W. (Munich) -- 84 Mpv17 Mouse Strain -A Model for the Relationship between the Kidney and the Inner Ear -- Meyer zum Gottesberge, A.M.; Balz, V. (Diisseldorf); Felix, H. (Zurich) -- Ototoxicity, Noise and Aging -- 91 Sensitivity to Glutamate Neurotoxicity in Different Developmental Periods of the Rat Cochlea -- Carricondo, F; Bartolome, M.V; Vicente-Torres, M.A.; Fernmndez-Pacheco, P.; -- Rodriguez, T.; Gil-Loyzaga, P. (Madrid) -- 96 Protective Mechanisms of Sound Conditioning -- Niu, X.; Canlon, B. (Stockholm) -- 106 Effects of Aging on C57BL/6J Mice: An Electrophysiological and Morphological Study -- Bartolom6, M.V; del Castillo, E.; L6pez, L.M.; Carricondo, F.; Poch-Broto, J.; -- Gil-Loyzaga, P. (Madrid) -- 112 Effects of Aging on Cochlear MonoamineTurnover -- Vicente-Torres, M.A.; Davila, D.; Mufioz, E.; Gil-Loyzaga, P. (Madrid) -- 116 Degeneration Pattern of Human First-Order Cochlear Neurons -- Felix, H.; Pollak, A. (Zfirich); Gleeson, M. (London); Johnsson, L.-G. (Helsinki) -- 124 The Inner Hair Cell Afferent/Efferent Synapses Revisited: A Basis for New Therapeutic Strategies -- Puel, J.-L.; Ruel, J.; Guitton, M.; Pujol, R. (Montpellier) -- 131 Neurotransmission of the Cochlear Inner Hair Cell Synapse - Implications for Inner Ear Therapy -- Oestreicher, E. (Munich/Berne); Arnold, W. (Munich); Felix, D. (Berne) -- 140 Simulation of Methods for Drug Delivery to the Cochlear Fluids -- Salt, A.N. (St. Louis) -- 149 Transtympanic Endoscopy for Drug Delivery to the Inner Ear Using a New Microendoscope -- Plontke, S.K.-R. (Tuibingen); Plinkert, PK.; Plinkert, B. (Tiibingen/Homburg, Saar); -- Koitschev, A.; Zenner, H.-P.; L6wenheim, H. (Tiibingen) -- 156 Clinical Experience with Caroverine in Inner Ear Diseases -- Ehrenberger, K. (Vienna).
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    Abt. 2. Knochen, Bänder -- Abt. 3. Muskeln, Gefässe -- Abt. 4. Eingeweide -- Abt. 5/6. Nervensystem, Sinnesorgane : nebst Anhang, Grundzüge der Oberflächen- und Projektions-Anatomie.
  • "Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms. They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc. The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer's disease could be stabilized by one or both these drugs."--P. [4] of cover.
  • Rb as a positive transcriptional regulator during epithelial differentiation / Chantal E. Crémisi and Linda L. Pritchard -- pRb in the differentiation of normal and neoplastic cells / Deborah Pajalunga, Grazia Camarda and Marco Crescenzi -- Regulation of DNA replication by the retinoblastoma tumor suppressor protein / Erik S. Knudsen and Steven P. Angus -- New insights into transcriptional regulation by Rb : one size no longer fits all / Peggy J. Farnham -- Regulation of Rb function by noncyclin dependent kinases / Jaya Padmanabhan and Srikumar P. Chellappan -- Diverse regulatory functions of the E2F family of transcription factors / Fred Dick and Nicholas Dyson -- Regulation of E2F-responsive genes through histone modifications / Estelle Nicolas, Laetitia Daury and Didier Trouche -- Emerging roles for the retinoblastoma gene family / Jacqueline L. Vanderluit, Kerry L. Ferguson and Ruth S. Slack -- Rb and cellular differentiation / Lucia Latella and Pier Lorenzo Puri.
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    "Tell the doctor where it hurts." It sounds simple enough, unless the problem affects the very organ that produces awareness and generates speech. What is it like to try to heal the body when the mind is under attack? In this book, Dr. Allan Ropper and Brian Burrell take the reader behind the scenes at Harvard Medical School's neurology unit to show how a seasoned diagnostician faces down bizarre, life-altering afflictions. Like Alice in Wonderland, Dr. Ropper inhabits a world where absurdities abound: A figure skater whose body has become a ticking time-bomb. A salesman who drives around and around a traffic rotary, unable to get off. A college quarterback who can't stop calling the same play. A child molester who, after falling on the ice, is left with a brain that is very much dead inside a body that is very much alive. A mother of two young girls, diagnosed with ALS, who has to decide whether a life locked inside her own head is worth living. How does one begin to treat such cases, to counsel people whose lives may be changed forever? How does one train the next generation of clinicians to deal with the moral and medical aspects of brain disease? Dr. Ropper and his colleague answer these questions by taking the reader into a rarified world where lives and minds hang in the balance"-- Provided by publisher.
  • Machine generated contents note: 1.Introduction -- Format of the Exercise -- What Is Attachment? -- The Place of Attachment in Nature -- The Process of Attachment in Early Childhood -- Definition of Reactive Attachment Disorder (RAD) -- Differential Diagnosis -- Comorbidity -- 2.Vignette of "Jorge" -- pt. 1 Jorge as a Toddler -- Case Point: International Adoption -- pt. 2 Jorge at Preschool Age -- Case Point: Neglect, Growth, and Medical Problems -- pt. 3 Jorge in Kindergarten -- Case Point: The Retrospective Evaluation of Child Abuse -- pt. 4 Jorge in First Grade -- Case Point: Alexythymia and Attachment -- pt. 5 Jorge in Second and Third Grades -- Case Point: Longitudinal Course and the Trait of Indiscriminate Friendliness -- pt. 6 Jorge in fourth and fourth Grades -- Test #1 Case-Related Questions -- 3.Theories for the Origin of RAD -- pt. 1 Biological Basis -- Genetic Coding of Attachment -- Epigenetic Models -- Biological Effect of Maternal Stress -- Maturation and Lesions of Early Limbic Pathways -- Stress Tolerance and the Developing Brain -- Physiological Measurement of Attachment Disorder -- pt. 2 Psychological Factors -- A Deficit Model -- The Application of Joint Attention to Attachment -- Avoidance and Detachment -- The Phenomenon of Shame -- The Impact of Trauma -- pt. 3 Social Origins -- Attachment and Social Impairment -- Theory of Mind and the False Belief Test -- Anticipatory Interactive Planning -- 4.A Discussion and Critique of RAD -- 5.Therapy for RAD -- Test #2 Theory Questions -- B.Matching Section.
  • The drug discovery business to date -- The drug discovery business to come -- Industrial considerations -- how things get done : the project team -- Project considerations -- Hit generation -- Turning hits into drugs -- Initial properties -- ADME and PK properties -- Toxicity related properties -- A career in drug discovery research.
  • This book describes the use of real-time three-dimensional transesophageal echocardiography (3D TEE) in percutaneous interventional procedures, underlining its growing role and acceptance among interventional cardiologists, while also considering technique-related weaknesses.
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    An introduction to real-time PCR / Gregory L. Shipley -- Data analysis and reporting / Pamela Scott Adams -- Relative quantification / Michael W. Pfaffl -- Normalization / Jim Huggett, Keertan Dheda and Stephen A. Bustin -- High-throughput primer and probe design / Xiaowei Wang and Brian Seed -- Quantitative analysis of ocular gene expression / Stuart N. Peirson -- Quantitative gene expression by real-time PCR / Thomas D. Schmittgen -- Real-time PCR using SYBR Green / Frederique Ponchel -- High-resolution melting analysis for scanning and genotyping / Virginie Dujols ... [et al.] -- Quantitative analyses of DNA methylation / Lin Zhou and James (Jianming) Tang -- Mitochondrial DNA analysis / Steve E. Durham and Patrick F. Chinnery -- Real-time immuno-PCR / Kristina Lind and Mikael Kubista -- Clinical microbiology / Burcu Cakilci and Mehmet Gunduz -- Clinical virology / David M. Whiley and Theo P. Sloots -- Solid organ transplant monitoring / Omaima M. Sabek -- Real-time PCR applications in hematology / Anne M. Sproul -- Real-time PCR for prenatal diagnosis of monogenic diseases caused by single nucleotide changes / Joanne Traeger-Synodinos, Christina Vrettou and Emmanuel Kanavakis.
  • ch. 1. Introduction, p. 1-9 -- ch. 2. Analysis and Verification of Non-Real-Time Systems, p. 10-40 -- ch. 3. Real-Time Scheduling and Schedulability Analysis, p. 41-85 -- ch. 4. Model Checking of Finite-State Systems, p. 86-133 -- ch. 5. Visual Formalism, Statecharts, and Statemate, p. 134-147 -- ch. 6. Real-Time Logic, Graph-Theoretic Analysis, and Modechart, p. 148-186 -- ch. 7. Verification Using Timed Automata, p. 187-211 -- ch. 8. Timed Petri Nets, p. 212-236 -- ch. 9. Process Algebra, p. 237-258 -- ch. 10. Design and Analysis of Propositional-Logic Rule-Based Systems, p. 259-366 -- ch. 11. Timing Analysis of Predicate-Logic Rule-Based Systems, p. 367-435 -- ch. 12. Optimization of Rule-Based Systems, p. 436-465.
  • Technology and 3D Imaging -- 3D TEE Basic Views -- Native Cardiac Valves -- Cardiac Prosthetic Valves -- Left and Right Ventricles 3D Imaging -- Cardiomyopathy Ventricles 3D Imaging -- Aorta -- Cardiac Masses 3D Imaging -- Congenital Heart 3D Imaging -- Miscellaneous 3D Imaging.
  • Introduction -- Assessment of subclinical organ damage for stratification of total cardiovascular risk -- Treatment approach -- Treatment strategies -- Therapeutic approach in special conditions -- Treatment of associated risk factors -- New trials needed.
  • This book argues that in order to be truly effective, public health must embrace a group of reasoning strategies that have traditionally been characterized as informal fallacies. It will be demonstrated that these strategies can facilitate judgements about complex public health issues in contexts of uncertainty. The book explains how scientists and lay people routinely resort to the use of these strategies during consideration of public health problems. Although these strategies are not deductively valid, they are nevertheless rationally warranted procedures. Public health professionals must have a sound understanding of these cognitive strategies in order to engage the public and achieve their public health goals. The book draws upon public health issues as wide ranging as infectious diseases, food safety and the potential impact on human health of new technologies. It examines reasoning in the context of these issues within a large-scale, questionnaire-based survey of nearly 900 members of the public in the UK. In addition, several philosophical themes run throughout the book, including the nature of uncertainty, scientific knowledge and inquiry. The complexity of many public health problems demands an approach to reasoning that cannot be accommodated satisfactorily within a general thinking skills framework. This book shows that by developing an awareness of these reasoning strategies, scientists and members of the public can have a more productive engagement with public health problems.
  • Cancer continues to be one of the major causes of death throughout the developed world, which has led to increased research on effective treatments. Because of this, in the past decade, rapid progress in the field of cancer treatment has been seen. Recent Advances in Cancer Research and Therapy reviews in specific details some of the most effective and promising treatments developed in research centers worldwide. While referencing advances in traditional therapies and treatments such as chemotherapy, this book also highlights advances in biotherapy including research using Interferon and Super.
  • Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays * Discusses many new assays developed since the previous edition. Presents recent developments in cytometric intrumentation/technology.
  • Cytometry is one of the most rapidly growing methodologies available for basic cell and molecular biology, cytogenetics, immunology, oncology, environmental sciences and also various fields of clinical medicine. This new edition, split into 2 Parts, is an almost completely new book, with nearly all of the chapters devoted to new topics. Like the previous volumes on cytometry published as part of the Methods in Cell Biology series, it provides a comprehensive description of particular cytometric methods and reviews their applications. Chapters present the theoretical foundations of the described methods, their applicability in experimental laboratory and clinical settings, and describes common traps and pitfalls such as problems with data interpretation, comparison with alternative assays, and choosing the optimal assay. Comprehensive presentation of cytometric methods covering theoretical applications, applicability, potential pitfalls, and comparisions to alternative assays. Discusses many new assays developed since the previous edition * Presents recent developments in cytometric intrumentation/technology.

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