Books

"The FIRST textbook to cover the principles and practice of ObGyn Hospitalist Medicine. ObGyn Hospitalist Medicine: Principles and Practice is the first text to encompass the core competencies in the emerging field of ObGyn Hospitalist Medicine. This groundbreaking text delivers comprehensive coverage of every aspect of ObGyn hospitalist medicine, encompassing clinical practice as well as program development and system implementation of ObGyn hospitalists. Readers will find a concise approach to the care of obstetrical and gynecologic emergencies in the hospital setting, with information that will be of value to physicians and physician extenders working in labor & delivery wards and ERs/ICUs. High-quality, easily approachable and comprehensive medical education material on the burgeoning field of ObGyn Hospitalist Medicine. Includes video clips of common obstetrical and gynecologic procedures and laboratory simulations. Chapters include learning objectives, clinical case presentations, key patient hand-off points, and abundant clinical images and illustrations"-- Provided by publisher

1. Getting the best answer: specimen handling and a quick review of the workings of the pathology laboratory -- 2. Normal histology of the female genital tract -- 3. Diseases of the vulva and anal neoplasia -- 4. Diseases of the vagina and urethra -- 5. Diseases of the cervix -- 6. Diseases of the endometrium -- 7. Diseases of the myometrium -- 8. Diseases of the fallopian tube -- 9. Diseaes of the ovary -- 10. Diseases of the broad ligaments and peritoneum -- 11. Pathology of the female genital tract related to pregnancy -- 12. Pathology of the placenta -- 13. Gestational trophoblastic neoplasia -- 14. Gynecologic cytology -- Index.

Top 100 secrets -- The menstrual cycle -- Premenstrual syndrome and dysmenorrhea -- Abnormal uterine bleeding -- Endometriosis and adenomyosis -- Leiomyomatous uterus -- Anovulation -- Female sexual dysfunction -- Menopause -- Benign lesions of the vulva and vagina -- Lower genital tract infections -- Pelvic inflammatory disease -- Ectopic pregnancy -- Induced abortion -- Contraception -- Benign adnexal masses -- Acute and chronic pelvic pain -- Urinary incontinence -- Pelvic organ prolapse -- Breast disease -- Intimate partner violence -- Puberty -- Amenorrhea -- Infertility -- Ovulation induction and in vitro fertilization -- Spontaneous abortion and recurrent pregnancy loss -- Hirsutism and polycystic ovarian syndrome -- Precancerous lesions of the lower genital tract -- Vulvar and vaginal cancer -- Cervical cancer -- Endometrial hyperplasia and uterine cancer -- Ovarian cancer -- Gestational trophoblastic disease -- Normal physiology of pregnancy -- Pathophysiology of the placenta -- Preconception counseling -- Comprehensive prenatal care -- Nutrition and exercise in pregnancy -- Obstetric ultrasound -- Prenatal diagnosis -- Antepartum fetal surveillance -- Genetics in pregnancy -- Cervical insufficiency and cerclage -- Nausea and vomiting in pregnancy -- Disorders of fetal growth -- Amniotic fluid disorders -- Alloimmunization -- Renal disease in pregnancy -- Pregestational and gestational diabetes -- Hypertension in pregnancy -- Thyroid disease in pregnancy -- Autoimmune diseases in pregnancy -- Neurologic issues in pregnancy -- Pulmonary disease in pregnancy -- Cardiovascular disease in pregnancy -- Infections in pregnancy -- Surgery during pregnancy -- Trauma in pregnancy -- Alcohol and drug abuse during pregnancy -- Obesity in pregnancy -- Multiple gestation -- Labor and vaginal delivery -- Intrapartum fetal surveillance -- Cesarean delivery and vaginal birth after cesarean delivery -- Obstetric anesthesia -- Preterm labor and preterm premature rupture of membranes -- Placenta previa and placental abruption -- Malpresentation -- Postpartum hemorrhage -- Newborn resuscitation -- Postpartum care.

1. White Adipose Tissues: Beyond Fat Storage -- 2. Brown Adipose Tissue and Obesity -- 3. Long-Chain Omega-3 Polyunsaturated Fatty Acids and Obesity -- 4. Leptin and Obesity -- 5. Role of Neuro-Endocrine System in Obesity -- 6. Oxidative Stress and Obesity -- 7. Genetics of Obesity -- 8. Obesity and Coronary Heart Disease -- 9. Obesity and Diabetes -- 10. Obesity and Breathing Related Sleep Disorder -- 11. Gastro-Oesophageal Reflux Disease and Obesity: Pathophysiology and Putative Treatment -- 12. Obesity and Gastrointestinal Disorder in Children -- 13. Non-Alcoholic Fatty Liver Disease in Obesity -- 14. Obesity, Cardiometabolic Risk, and Chronic Kidney Disease -- 15. Polycystic Ovary Syndrome and Obesity -- 16. Obesity and Cancer -- 17. Obesity and Thyroid Cancer -- 18. Depression and Obesity -- 19. Obesity in Orthopedics and Trauma Surgery -- 20. New Technology in the Assessment and Treatment of Obesity -- 21. Obstetrical Risk in Obesity -- 22. Bariatric Surgery in Obesity -- 23. Decoding the Code: Underlying Physiological Mechanisms of Bariatric Surgery -- 24. Infant Nutrition and Obesity -- 25. Disordered Eating and Obesity -- 26. Physical Activity in Obesity and Diabetes -- 27. Obesity Prevention in Young Children.

This book presents the latest advances in our understanding of the pathophysiologic basis that induces the chronic positive energy balance necessary to progressively store excessive amounts of fat mass. It highlights the clinical complications of obesity, while also focusing on the major scientific advances that have highlighted the role of genetics, adipose tissue endocrinology and the environment in the mechanisms and causes of obesity. Particular attention is given to the consequences of obesity, including an ever -increasing number of other diseases such as type 2 diabetes, cardiovascular diseases and cancer, as well as conditions such as arthropathy, asthma, non-alcoholic liver disease, and dementia. Increasingly recognized uniting causes highlight the role of systemic, local and paracrine actions of adipocytokines in causing inflammation. As we come to better understand how hypothalamic control of energy balance is influenced by endocrine signaling from the gut and adipose tissue, it paves the way for new therapeutic targets and a resurgence of pharmacological and surgical approaches to treatment. Written by respected experts in the field, this volume is intended as a major reference source for endocrinologists, nutritionists, basic and clinical scientists alike.

Obesity & pregnancy / Yariv Yogev & Eyal Sheiner -- The impact of obesity on maternal health / Bram P. Wispelwey & Eyal Sheiner -- Ask the experts : risks of obesity to pregnancy and fetal health / Amir Aviram & Yariv Yogev -- Screening and treatment of diabetes in obese pregnant women / Gerard H.A. Visser & Harold W. de Valk -- Prepregnancy weight optimization and care / Annunziata Lapolla & Maria Grazia Dalfra -- Considerations in antepartum management / Hugh M. Ehrenberg -- Outcomes in pregnancy following bariatric surgery / Aubrey R. Raimondi, Yariv Yogev & Eyal Sheiner -- Considerations for labor, delivery and postnatal care / Eran Ashwal & Yariv Yogev -- Maternal obesity and its long-term sequelae to the offspring / Justin B. Levinson & Eyal Sheiner -- Multiple choice questions : answers.

1. Epidemiology, measurement, cost of obesity -- 2. Prejudice, discrimation, and the preferred approach to the patient with obesity -- 3. The biology of weight regulation and genetic resetting -- 4. The biology of adipose tissue -- 5. Obesity-related diseases and syndromes: insulin resistance, Type 2 diabetes mellitus, non-alcoholic fatty liver disease, cardiovascular disease, and metabolic syndrome -- 6. Obesity-related diseases and syndromes: cancer, endocrine disease, pulmonary disease, pseudotumor cerebri, and disordered sleep -- 7. Pediatric obesity -- 8. Fundamentals of diet, exercise, and behavior modification -- 9. The assessment of the adult patient with overweight and obesity -- 10. Beyond traditional management: the use of medications in the treatment of obesity -- 11. Bariatric surgery -- 12. Population health management of obesity -- Index.

Section I. Obesity and metabolic syndrome -- Section II. Introduction to bariatric surgery -- Section III. Perioperative assessment for bariatric surgery -- Section IV. Laparoscopic Roux-en-Y Gastric Bypass (LRYGB): techniques, complications, outcomes, and controversies -- Section V. Laparoscopic Sleeve Gastrectomy (LSG): technique, complications, outcomes, and controversies -- Section VI. Laparoscopic Adjustable Gastric Banding (LAGB): technique, complications, outcomes and controversies -- Section VII. Advances in minimally invasive bariatric surgery -- Section VIII. Revisional bariatric surgery -- Section IX. Other operations for obesity -- Section X. Endoscopic approaches in obesity and bariatric surgery -- Section XI. Metabolic effects of bariatric surgery -- Section XII. Training, reporting, and practice in bariatric surgery -- Section XIII. Miscellaneous topics -- Section XIV. Special topics.

1. Introduction -- 2. Epidemiology and etiologic associations of non-alcoholic fatty liver disease and associated HCC -- 3. Pathogenesis of NASH: how metabolic complications of overnutrition favour lipotoxicity and pro-inflammatory fatty liver disease -- 4. Chemokines and chemokine receptors in the development of NAFLD -- 5. NAFLD related-HCC: the relationship with metabolic disorders -- 6. Hepatocellular carcinoma in obesity: finding a needle in the haystack? -- 7. Dysregulated epigenetic modifications in the pathogenesis of NAFLD-HCC -- 8. The influence of gut microbial metabolism on the development and progression of non-alcoholic fatty liver disease -- 9. Microbiota, obesity and NAFLD -- 10. Autophagy, NAFLD and NAFLD-related HCC -- 11. Animal models of non-alcoholic fatty liver diseases and its associated liver cancer -- 12. Current prevention and treatment options for NAFLD.

In addition to their metabolic and endocrinologic effects, obesity and adipose tissue have now been shown to be associated with chronic low grade inflammation resulting in cellular and humoral factors of which the latter may act by endocrine, paracrine and autocrine mechanisms. These inflammatory mediators have increasingly been suggested as contributing to the obesity link to carcinogenesis and cancer promotion. Obesity, Inflammation and Cancer focuses on recent developments and cutting edge research pointing to inflammation and inflammatory factors as key mediators of this linkage. It also describes possible strategies for targeting inflammation as an approach to cancer prevention and control. Students, researchers and clinicians, especially those interested in the relation of obesity to cancer and the role of inflammation and its impact on cancer, will find this volume particularly useful. It provides important insight on the role of inflammation in cancer etiology and progression and serve as a platform for developing future research in this area.

The Adipose Organ -- Brown Adipose Tissue (BAT) -- White Adipose Tissue (WAT) -- The Adipose Organ: Cold Acclimation -- BAT -- WAT -- The Adipose Organ: Warm Acclimation: BAT -- The Obese Adipose Organ: BAT -- The Fasted Adipose Organ: WAT -- BAT -- The Adipose Organ During Lactation: WAT -- BAT -- The Fetal Adipose Organ -- The Adipose Organ In Genetically Modified Models.

Obesity is a risk factor for breast cancer in older women. A number of adipose-derived and obesity-related factors have been shown to affect tumour cell growth. These include adipokines, insulin, IGF-1 and oestrogens. The majority of obesity-related postmenopausal breast cancers are oestrogen-dependent. Since the ovaries no longer produce oestrogens after menopause, and that circulating levels are negligible, it is evident that it is the oestrogens produced locally within the breast adipose that are responsible for the increased growth of breast cancer cells. Aromatase is the enzyme that converts androgens into oestrogens and its regulation is dependent on the activity of a number of tissue-specific promoters.Targeting oestrogen biosynthesis in obesity may be useful for the prevention of breast cancer.Aromatase inhibitors are efficacious at treating postmenopausal breast cancer and recent studies suggest that they may also be useful in the prevention setting. However, these compounds inhibit the catalytic activity of aromatase and as a consequence lead to a number of undesirable side-effects, including arthralgia and possible cognitive defects due to inhibition of aromatase in the bone and brain, respectively. Novel therapies, such as those employed to treat obesity-associated disease, including anti-diabetics, may prove successful at inhibiting aromatase specifically within the breast.This SpringerBrief will explore all of these issues in depth and the authorsare in a unique position to write about this topic,havingextensive experience in the field of aromatase research.

Obesity and risk of cancer: an introductory overview -- Obesity and colorectal cancer -- Obesity and breast cancer -- Obesity and oesophageal cancer -- Obesity and kidney cancer -- Obesity and pancreatic cancer -- Obesity and endometrial cancer -- Obesity and prostate cancer -- Obesity and ovarian cancer -- Obesity and liver cancer -- Obesity biomarkers, metabolism and risk of cancer: an epidemiological perspective -- Biological mechanisms for the effect of obesity on cancer risk: experimental evidence -- Obesity as an avoidable cause of cancer (attributable risks).

Obesity and childhood / Krista R. Casazza & Lynae J. Hanks -- Conceptualization and predictive environmental factors for childhood obesity / Sandra Verbeken, Ellen Moens, Lien Goossens & Caroline Braet -- Genetic contributors to pediatric obesity : beyond more iterations of BMI / Lynae J. Hanks, Anna L. Newton, Danielle Lorch, Pranayraj Kondapally & Krista R. Casazza -- Parenting and management of pediatric obesity / Moria Golan -- Role as a public health concern: need for prevention across the lifecycle / Mary Jo Messito -- Dietary intake and childhood obesity / Abigail E. Duffine & Stella L. Volpe -- Psychosocial stresses in pediatric obesity : what comes into the room with an obese child and their parents? / Gerri Minshall & Shirley Alexander -- Ask the experts : differences in interventions : special considerations for sex, stage of development and ethnicity / Krista R. Casazza and Lynae J. Hanks -- Multiple choice questions : answers.

This timely and clinically oriented book uniquely addresses the entire spectrum of treatment for severe obesity and diabetes. It thoroughly examines all aspects from robotic surgery to cell therapy, from the latest antidiabetic drugs to endoscopic procedures and devices, from appetite-inhibiting signals and nutrients to gastric arterial embolization. It offers objective and authoritative information for practicing professionals; not only are successful interventions discussed and updated, but cutting-edge and experimental pathways are also anticipated. Obesity is the foremost nutritional challenge worldwide. Its companion is type-2 diabetes, the most prevalent metabolic disease. Together they represent the diabesity epidemic, which is draining resources, overwhelming healthcare facilities, and impacting life expectancy and quality of life everywhere. No country has been spared, and most medical specialties have been affected. Many books focus on the surgical options for obesity and diabetes, namely bariatric and metabolic operations. Information on the clinical and pharmacological treatment is also available, conveyed by standard texts on internal medicine and endocrinology. Yet endoscopic maneuvers and prostheses, cell therapy for diabetes, and other innovative approaches are hard to come by, as conventional texts overlook such therapies. This timely publication bridges the gaps between all different therapeutic options, also covering advances in the conservative, surgical and parasurgical domains. This book will appeal to seasoned specialists, students and healthcare professionals in training alike.

"AM:STARs is the official publication of the AAP Section on Adolescent Health. Published 2 times per year, it offers adolescent specialists and primary care physicians timely information on matters relating to adolescent health and wellness. The AM:STARs Obesity and Diabetes in the Adolescent covers a wide variety of topics including: type I and type II diabetes - diagnosis/evaluation/treatment & future treatments being developed; how to distinguish between type I and type II; insulin resistance; pre-diabetes and the metabolic syndrome; dyslipidemia evaluation and treatment; disorders of growth and puberty in obesity; overlooked complications of obesity; laboratory evaluation of obesity; nutritional management of obesity; hypertension and sleep apnea; behavioral approaches in adolescent weight management; weight bias/stigma in overweight adolescents; adolescent weight management in the primary care setting; physical activity promotion in the adolescent patient; [and] genetics of obesity"--Publisher's description.

Introduction to Obesity and Fertility -- Obesity and the HPO axis -- Childhood and Adolescent Obesity: Implications for Reproductive Health and Function -- Nutrition in Human Fertility -- Preconceptional Obesity and Fetal Outcomes?Transdisciplinary Evidence for Obesity?s Effects on Fertility -- Fertility Treatment Outcomes in Obese Women -- Early Pregnancy in Obese Women -- Obesity in Pregnancy -- Contraceptive Counseling in Obese Women -- Obesity and Ovarian Aging (Diminished Ovarian Reserve and Menopause) -- Obesity, Reproductive Outcomes, and Access to Infertility Treatments: A Clinical and Ethical Debate -- Surgical Interventions and Reproductive Function in Obese Women -- Conclusions: Establishing an Ethically and Medically Sound Framework for Integrating BMI Limits Into Infertility Care for Obese Women.

This book summarizes the effects of obesity on health and its correlation with a wide range of debilitating and life-threatening conditions in humans. It discusses the possible pathological mechanisms that are involved in the development of obesity and highlights obesity-associated molecular mechanisms that contribute to reproductive dysfunctions in men and women. The book provides mechanistic insights on the role of obesity in cardiovascular and respiratory disorders, and examines the role of the complementary molecular mechanism of the gut microbiota in the development of obesity. It also reviews the interaction between the metabolic system and immune cells in the pathogenesis of obesity-associated diseases. Lastly, it assesses the latest advances in nanomedicine as an emerging strategy for the treatment of obesity.

"Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. "Obesity and Lipotoxicity" is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. "Lipotoxicity and Obesity" will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field"--Publisher's description.

As a result of the rapidly growing rate of obesity worldwide, clinicians are struggling to provide the best strategies for treating obese patients with concomitant pulmonary conditions. Obesity does not simply change the epidemiology of pulmonary disease; obesity has a profound impact on the pathophysiology of common pulmonary diseases. Obesity affects the severity of asthma, response to treatment, and is likely a major modifier of the phenotype of asthma. Obesity also appears to affect response to pathogens, and as such has a major influence on response to pneumonia, and has a significant impact on outcomes pertaining to acute lung injury in the intensive care unit. Obesity and Lung Disease: A Guide to Management is the first text in the field to cover the full range of issues related to managing obese patients with pulmonary problems.

Procedures and perspectives of obesity and metabolic surgery This book presents the surgical therapy of obesity and metabolic diseases in a practice-oriented and detailed way. The specific surgical procedures with their indications, performance and risks are described precisely in words and pictures. Special emphasis is placed on the choice of the appropriate surgical procedure for the individual patient. In addition to the mechanisms of action, interdisciplinary preoperative evaluation of the patient and postoperative aftercare are explained. Furthermore, surgical, internal and psychosomatic complications and complication management are described. Information on obesity center organization and alternative bariatric therapies complete the volume. This book is a translation of the original German 1st edition Adipositas- und metabolische Chirurgie by Jurgen Ordemann & Ulf Elbelt, published by Springer-Verlag GmbH Germany, part of Springer Nature in 2017. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. Springer Nature works continuously to further the development of tools for the production of books and on the related technologies to support the authors. The Content: Obesity, Conservative obesity therapy, Weight-loss surgery, Metabolic surgery, Preoperative evaluation, Anesthesia, Surgical procedure, Roux-en-Y gastric bypass, Sleeve gastrectomy, Omega-loop bypass, Gastric banding, Biliopancreatic diversion, Redo-operation, Postoperative aftercare, Complications and management of complications The Editors: Professor Dr. med. Jurgen Ordemann, former holder of the professorship for Obesity Surgery at the Charite Universitatsmedizin Berlin and since 2018 Head of the Department of Obesity and Metabolic Surgery, Vivantes Klinikum Berlin-Spandau Priv.-Doz. Dr. med. Ulf Elbelt, former Senior Physician at the Medical Department of Endocrinology and Metabolic Diseases, Charite - Universitatsmedizin Berlin and since 2019 Senior Physician for Endocrinology at Brandenburg Medical School.

Section I. Introduction -- 1. Introduction: Breaking the Cycle of Obesity in Mothers and Children -- 2. Obesity and infertility -- 3. Preconception and Pregnancy Care in Overweight or Obese Women -- 4. hared Decision-Making and Labor Management in Parturients -- Section II. Translating the Metabolism of Pregnancy -- 5. Epidemiologic Trends and Maternal Factors Predicting Postpartum Weight -- 6. Relationship between depressive mood and maternal obesity- implications for postpartum depression -- 7. Body Image as a Contributor to Weight in Pregnancy and Postpartum -- Section III. The Event -- 8. Promoting a Healthy Weight After Delivery -- 9. Obesity and Physical Activity During Pregnancy and Postpartum: Evidence, Guidelines, and Recommendations -- 10. Maternal obesity, gestational weight gain, and childhood growth in the first year of life -- Section IV. Meeting the Challenges -- 11. ernal Obesity and Implications for the Long-term Health of the Offspring -- 12. Family- centered interventions to reduce maternal and child obesity -- 13. Obesity Screening Recommendations and Emerging Policies.

Comprised exclusively of clinical cases illustrating current strategies for obesity management across various types of conditions, this concise, practical casebook will provide obesity medicine specialists and all physicians who treat obesity with the best real-world strategies to properly diagnose and treat patients struggling with weight management. Each section includes a pair of cases that open with a unique clinical presentation, followed by a description of the diagnosis, assessment and management technique recommended and employed, as well as the case outcome and clinical pearls and pitfalls. Cases included in the first sections depict issues involved in obesity management in metabolic syndrome, cardiovascular disease, insulin resistance syndromes, genetic predisposition, and type 2 diabetes. Subsequent sections present cases highlighting particular management strategies, such as psychiatric medication induced weight gain, behavioral interventions, bariatric surgery and pharmacotherapy for obesity. Pragmatic and reader-friendly, Obesity Management: A Clinical Casebook is an excellent resource for physicians who treat overweight and obesity and the complications of these conditions.

A text that comprehensively addresses both the gynecologic and obstetrical care of the obese patient. It provides clinicians with the tools needed to manage care and minimize risk of complications. Clinically focused and evidence based, it concludes with a section devoted to related conditions that would further impact patient care

"With a mix of theory, practical advice, and illustrative clinical material, The Object Relations Lens is a compelling and indispensable resource for any clinician interested in applying the object relations model to their clinical or academic work. As accessible to trainees as it is to experienced clinicians, Dr. Christopher Miller clearly outlines object relations theory, leveraging clinical vignettes to underline the framework's applicability both in therapy and acute care settings. Readers in academic settings will also find experience-near ways of assimilating the concepts introduced in the book, as well as best practices for utilizing supervision and extensive literature recommendations. With a detailed discussion of the neuroscientific model of object relations and the integration of concepts from other schools of psychoanalytic thought that help consolidate certain discussion points, this volume will provide readers with an updated and scientifically informed understanding of how object relations theory can be harmonized with psychiatric theory and practice"-- Provided by publisher.

Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders provides a new and unifying methodological framework, introducing new objective biometrics to characterize patterns of sensory motor control underlying symptoms. Its goal is to radically transform the ways in which disorders of the nervous system are currently diagnosed, tracked, researched and treated. This book iintroduces new ways to bring the laboratory to the clinical setting, to schools and to settings of occupational and physical therapy. Ready-to-use, graphic user interfaces are introduced to provide outcome measures from wearable sensors that automatically assess in near real time the effectiveness of interventions. Lastly, examples of how the new framework has been effectively utilized in the context of clinical trials are provided.

1. Physical activity and optimal health: the callenge to epidemiology -- 2. A history of physical activity measurement in epidemiology -- 3. Outputs available from objective monitors -- 4. Protocols for data collection, management and treatment -- 5. Resources for data interpretation and reporting -- 6. New information on population activity patterns revealed by objective monitoring -- 7. Can the epidemiologist learn more from sedentary behaviour than from the measurement of physical activity? -- 8. New perspectives on activity/ disease relationships yielded by objective monitoring -- 9. Excessive appetite vs. inadequate physical activity in the pathology of obesity: evidence from objective monitoring -- 10. Objective monitoring and the challenge of defining dose/response relationships for the prevention of chronic disease -- 11. The economic benefits of increased physical activity as seen through an objective lens -- 12. Limitations of current objective monitors and opportunities to overcome these problems -- 13. Objective measurement in physical activity surveillance: present role and future potential -- 14. Self-report and direct measures of health: bias and implications -- 15. Conclusions and future directions.

Objective structured clinical examinations (OSCEs) and other exercises that utilize standardized patients (SPs) can simulate actual clinician-patient encounters with great impact. They are one of the most effective methods for training and assessing competencies across undergraduate, (post)graduate, and continuing health professions education. However, organizing such programs requires strong leadership and the collaboration of many key individuals for planning and implementation. This book, Objective Structured Clinical Exams: 10 Steps to Planning and Implementing OSCEs and other Standardized Patient Exercises, serves as a comprehensive how-to manual and addresses the need for best practice guidelines. It contains a review of relevant literature, pointers for designing OSCE cases, tips on recruiting and training standardized patients, and it describes innovative uses of standardized patients for remediation and assessment in clinical settings. Charts, graphs, and sample forms are included to make this a singular resource for any educator interested in creating or improving OSCEs and other standardized patient programs.

--v.1, The structure of the body: cells, tissues and skin; case histories and questions based on nursing care of gastro-enteritis, undernutrition and infestation ; v.2, The skeletal system and the muscular system ; v.3, The circulatory system and the respiratory system ; v.4, The digestive system and the urinary system

1. Deontología médica -- 2. Divulgacion -- 3. Biologia -- 4. Cirugia -- 5. Obstetricia -- 6. Higene y medicina social -- 7. Anatomia y varios.

1. Buch. Funktionelle Störungen des Sinnes und der Bewegung.

"Obsessive-compulsive disorders affects between 1 and 3 percent of the population. Ranging from relatively mild symptoms to being a profoundly disabling disorder, it is a condition that is amenable to modern treatments. This book examines the evidence for and potential role of a range of treatment methods, from CBT to pharmacological approaches. It asks what an individual can do to help themselves, and how friends and relatives can assist in the recovery process. Although firmly based in clinical research, it is written in a jargon-free and accessible style to help provide deep understanding of the disorder. Personal narratives and case studies of people living with OCD feature to illustrate points, and the book considers emerging research and the future of approaches to OCD. Built upon decades of experience, this guide will inform and support adults and young people living with OCD, as well as carers, families and health professionals"-- Provided by publisher. "This book arises out of my experience with people living with OCD and their families since the 1980s. When I was developing my interest in this area, few people had heard of OCD and those who had were often still confused about what it was. Today there appears, at first sight, to be much greater awareness. However, a higher profile in the media has also led to a frequent underestimation about how damaging and severe OCD can be. People now frequently quip that they are "a bit OCD" not understanding that in its severe forms, OCD destroys relationships and families and can lead to the early demise of the individual. OCD is not just being fussy or preferring an orderly life but is a serious, life-restricting psychological disorder which requires help and treatment. Fortunately we now have good and effective treatments which can alter the prognosis of OCD and lead to people living happy, fulfilled lives with minimal inconvenience from OCD symptoms. Despite this there is still often confusion about what the evidenced-based treatments are and how to ensure that the person receives the appropriate help and care they need. I am hoping that this book will help to bridge the gap. I have described what OCD is and how it can impact on families. There is then a full discussion concerning tried and tested treatments. I then examine more "experimental" and unusual treatments for that handful of individuals who do not gain benefit from standard treatments"-- Provided by publisher.

This book summarizes scientific advances in our understanding of the interrelationship between obsessive-compulsive symptoms (OCS) and schizophrenia and reflects on the implications for future research directions. In addition, guidelines are provided on practical assessment, diagnosis, and treatment interventions, covering both pharmacotherapy and psychotherapy. Full account is taken of the fact that the variable clinical presentation regarding time of onset and course of OCS in patients with schizophrenia strongly suggests the need for a perspective that recognizes heterogeneous subgroups and diverse neurobiological explanations. Research-based multidimensional conceptual frameworks are accordingly provided relating to the co-occurrence of the disorders, incorporating recent epidemiological, neurocognitive, neurogenetic, and pharmacodynamic findings. Obsessive-Compulsive Symptoms in Schizophrenia has been written by an international team of experts who offer insights gained through their extensive experience. It will be an invaluable guide to this frequent and clinically important comorbidity and will be particularly useful for mental health practitioners.

This highly illustrated manual is ideal for both the trainee and experienced sonographer that covers the full range of obstetric and gynaecological ultrasound examinations undertaken within a secondary referral setting. It combines the practicalities of how to perform these examinations with the information needed to interpret the findings and construct a clinically useful report. The new edition of this well-established book expands its scope to provide an understanding of ultrasound imaging within the clinical management of the gynaecological patient. Elsewhere, its obstetric content has been fully updated with the latest technological, clinical and medico-legal information relevant to routine practice. Furthermore, its experienced sonographer authors continue to advise on the practical aspects of scanning as well as the role, value and limitations of ultrasound in the diagnosis of different diseases thus providing firm foundations in both obstetric and gynaecological imaging. -- Back cover.

The female patient with chronic kidney disease often requires care that differs from the male patient. Particularly in the pregnant patient, a specialized body of knowledge is required to provide optimal care. This book focuses on such issues encountered during pregnancy including physiology and pathophysiology of pregnancy, hypertension, preeclampsia, various electrolyte disorders, nephrolithiasis, pharmacological management in the pregnant patient with kidney disease and during breastfeeding, acute kidney and chronic kidney disease, dialysis of the pregnant patient, lupus nephritis, thrombotic microangiopathy, glomerular disease management, use of renal biopsy during pregnancy, care of the female transplant patient, contraceptive counseling and postpartum care, various endocrine disorders, and bone disease in the female patient with chronic kidney disease. This book features the latest evidence and clinical approaches for the beginner or for the experienced practitioners who care for pregnant woman or even for those who require expertise in women's health. Written by experts in the field, Obstetric and Gynecologic Nephrology: Women's Health Issues in the Patient with Kidney Disease is a valuable resource for clinicians and practitioners involved in the care and treatment of obstetric and gynecologic patients afflicted with kidney disease. .

With 32 engaging and dramatic cases and 174 colorful, insightful and innovative graphics, this book takes a fresh, creative and highly visual approach to the fundamentals of obstetric anesthesia as well as emerging knowledge and three emerging technologies: 1) pre-procedural ultrasound to facilitate neuraxial block placement, 2) point-of-care transthoracic echocardiography to guide maternal resuscitation, and 3) electrical cardiometry to trend maternal cardiac output and avoid fetal hypoxia. Besides discussing the threats to fetal oxygenation presented by labor and the avoidance of maternal and fetal complications while providing excellent anesthesia, the book also explores the psychological and behavioral dimensions of obstetric anesthesia practice and promotes the obstetric anesthesiologist as a valued member of the obstetric care team who makes unique, insightful and empathic contributions to the overall excellent care of pregnant patients. Obstetric Anesthesia: A Case-Based and Visual Approach is an indispensable resource for medical students, residents, fellows, anesthesiologists, nurse anesthetists, nurse midwives, and obstetricians.

"This textbook features a succinct, evidence-based review tied with practical and clinical protocols for each important topic in the anesthetic care of the pregnant woman"-- Provided by publisher.

"The complex healthcare needs of pregnant patients, where care is tailored to not one but two patients, pose specific challenges to anesthesiologists. This book provides concise, case-based discussion on the clinical scenarios and challenges faced in the provision of anesthesia and pain relief for expectant mothers. In the style of problem-based learning, each case is presented as a short scenario, followed by discussion of the causes, risk factors, management and controversies involved. The textbook features a wide range of cases, from common clinical scenarios that are experienced in day-to-day practice to the rare but significant pathologies less familiar to most clinicians. With a global base of contributors, the book is relevant to practice across the world. The concise format supports both trainee anesthesiologists in their initial experiences of obstetrics and exam preparation, and experienced clinicians in need of a reliable, quick-reference text"--Provided by publisher.

Front Matter -- Preventative Health. Abnormal Pap Smear in Pregnancy -- Immunization -- Preconception Care -- Prenatal Care1 -- Maternal Disorders. Antiphospholipid Antibody Syndrome -- Asthma -- Cholestasis of Pregnancy -- Chronic Hypertension1 -- Deep Vein Thrombosis -- Gestational Diabetes Mellitus1,2 -- Gestational Hypertension1 -- Preeclampsia -- Pregestational Diabetes Mellitus -- Pulmonary Edema -- Pulmonary Embolism1 -- Renal Disease -- Seizure Disorder -- Systemic Lupus Erythematosus -- Thrombocytopenia -- Thyroid Dysfunction -- Infectious Complications. Asymptomatic Bacteriuria1 -- Urinary Tract Infection/Pyelonephritis -- Lower Genital Tract Infection -- Group B [beta]-Hemolytic Streptococcus1 -- Hepatitis B -- Herpes Simplex Virus -- Human Immunodeficiency Virus -- Parvovirus B19 -- Syphilis -- Tuberculosis1 -- Chorioamnionitis (Intraamniotic Infection)1 -- Antenatal Complications. Advanced Maternal Age -- Antepartum Fetal Testing1 -- Breast Lesions -- Cervical Insufficiency -- First‐trimester Vaginal Bleeding -- Higher-Order Multifetal Pregnancy -- Hyperemesis Gravidarum -- Intrauterine Fetal Demise -- Fetal Growth Restriction1 -- Isoimmunization -- Macrosomia -- Medically-Indicated Late Preterm and Early Term Delivery -- Obesity -- Oligohydramnios1 -- Recurrent Pregnancy Loss -- Placenta Accreta -- Placenta Previa -- Placental Abruption -- Polyhydramnios1 -- Post-term Pregnancy1 -- Pregnancy Termination -- Prenatal Diagnosis -- Preterm Labor -- Screening for Preterm Birth -- Preterm Premature Rupture of the Membranes1 -- Vaginal Birth after Cesarean (VBAC) -- Teratology -- Term Premature Rupture of the Membranes1 -- Twin Pregnancy -- Intrapartum/Postpartum Complications. Breech Presentation -- Intrapartum Fetal Testing1 -- Cesarean Delivery -- Operative Vaginal Delivery1 -- Severe Perineal Lacerations1 -- Intrapartum Management of Twin Pregnancy -- Postpartum Hemorrhage1 -- Retained Placenta -- Postpartum Endomyometritis1 -- Mastitis -- Vasa Previa -- Postpartum Psychiatric Disorders -- Sterilization1 -- Obstetric Emergencies. Acute Abdomen in Pregnancy -- Acute Asthma Exacerbation -- Acute Shortness of Breath -- Cord Prolapse -- Cardiopulmonary Resuscitation -- Diabetic Ketoacidosis1 -- Eclampsia -- Shoulder Dystocia1 -- Thyroid Storm -- Recommended Reading.

Simulation is becoming an integral part of medical education and has already a well-established role within anaesthesia training, with many examination questions already modelled on simulation scenarios. The clinical diversity and multidisciplinary nature of an obstetric team creates the ideal environment for simulation training. It enables the team to develop their knowledge of clinical emergencies whilst becoming more aware of the importance of human factors. This book is a practical guide to inspire clinical leads to establish simulation within their delivery suite. The book comprises an extensive obstetric scenario library, with each scenario broken down into learning outcomes, a list of staff and equipment needed, specific stages mapped to learning outcomes with appropriate results/investigations and a checklist of ideal actions to enable the post-scenario debrief. Written by consultant obstetric anaesthetists, this book will appeal to medical practitioners interested in facilitating obstetric simulation.

This book provides a practical guide to the management of obstetric emergencies? acute complications during pregnancy and childbirth that pose a life-threatening risk to the mother and/or the fetus, and whose treatment requires an almost immediate response from the healthcare team in order to guarantee a favorable outcome. The book covers two essential areas: the "predominately fetal" emergencies - acute fetal hypoxia/acidosis, shoulder dystocia, and retention of the aftercoming head; and the "predominately maternal" emergencies - eclampsia, maternal cardiorespiratory arrest and post-partum hemorrhage. The book offers a valuable guide for healthcare professionals who deal with obstetric patients, as they may use it for reviewing these rare situations and for consultation when they encounter them. It is also a useful reference manual for simulation-based courses designed to develop and maintain clinical expertise in this area. Healthcare professionals will find that this book offers a comprehensive and pan-European perspective on the clinical management of these situations, as well as a pragmatic and reliable source of information for dealing with acute complications of pregnancy and childbirth.

Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.

"Richly illustrated and comprehensive in scope, Obstetric Imaging, 2nd Edition, provides up-to-date, authoritative guidelines for more than 200 obstetric conditions and procedures, keeping you at the forefront of this fast-changing field. This highly regarded reference covers the extensive and ongoing advances in maternal and fetal imaging in a concise, newly streamlined format for quicker access to common and uncommon findings. Detailed, expert guidance, accompanied by superb, high-quality images, helps you make the most of new technologies and advances in obstetric imaging"--Publisher's description.

Basic hemodymanamic monitoring in obstetric patients -- Transfusion of blood components and derivatives in the obstertics intensive care patient -- Postpartum hemorrhage -- Disseminated intravascular coagulopathy and thrombocytopenia complicating pregnancy -- Hypertensive emergencies -- Management strategies and intensive care of the obese gravida -- Thromboembolic disease complicating pregnancy -- Cardiac disease in pregnancy -- Maternal sepsis -- Thyroid and other endocrine emergencies -- Diabetic ketoacidosis in pregnancy -- Respiratory emergencies during pregnancy -- Acute kidney injury in pregnancy -- Amniotic fluid embolism -- Acute fatty liver of pregnancy -- Neurologic emergencies during pregnancy -- Advanced cardiac life support of the pregnant patient -- Trauma and pregnancy -- Transport of the critically ill obstetric patient -- Anesthesia for the complicated obstetric patient -- Psychiatric emergencies in pregnancy -- Fetal considerations in the critical care patient -- Poisoning in pregnancy -- Neonatal resuscitation: pathophysiology, organization, and survival -- Fluid and electrolyte therapy in the critically ill obstetric patient -- Human immunodeficiency virus in pregnancy -- Systemic lupus erythematosus in the pregnant patient -- Management of a vaso-occlusive sickle cell crisis in pregnancy -- Abnormal placentation

Established as the standard resource of the obstetrics and gynecology clerkship, Obstetrics and Gynecology is now in its revised Seventh Edition. This is the only clerkship book on the market fully compliant with The American College of Obstetricians and Gynecologist (ACOG) guidelines, treatment recommendations, and committee opinions.

"Obstetrics and Gynecology: PreTest Self-Assessment and Review, 15th Edition, is intended to provide medical students, as well as physicians, with a convenient tool for assessing and improving their knowledge of obstetrics and gynecology"-- Provided by publisher.

I. Preconception and Prenatal Care -- Physiology -- Preconception Counseling -- Prenatal Care -- Medications in Pregnancy -- II. Complications of Pregnancy -- Dysmorphic Growth and Genetic Abnormalities -- Intrauterine Growth Restriction -- Preterm Labor -- Premature Rupture of Membranes -- Early Pregnancy Bleeding -- Late Pregnancy Bleeding -- Recurrent Pregnancy Loss -- Rh Isoimmunization -- Infection in Pregnancy -- Hypertension in Pregnancy -- Diabetes in Pregnancy -- Multi gestational Pregnancy -- Post-Dates Pregnancy -- III. Labor and Delivery -- Normal Labor -- Induction and Augmentation -- Pain Management in Labor -- Operative Delivery -- IV. Complications of Labor and Delivery -- Prolonged Labor -- Shoulder Dystocia -- Malpresentation -- Fetal Heart Rate Monitoring -- Maternal Fever in Labor -- Postpartum Hemorrhage -- Perineal Laceration and Episiotomy -- V. Postpartum Management -- Newborn Evaluation -- Routine Hospital Postpartum Management -- Complications of the Hospital Postpartum Period.

Obstetrical care in the family medicine setting is an ever-evolving discipline. In addition to routine updates due to the passage of time, several new developments have occurred in the field since the last edition of this book was published. Among these developments are advances in prenatal assessment and diagnosis, recommendations for vaccination in pregnancy, assessment and management of infectious disease in pregnancy, and management of chronic disease concurrent with pregnancy. All thirty-one chapters of the second edition of this text have been thoroughly updated. Several chapters warranted substantive expansion and revision due to the developments on the topic. These chapters include preconception counseling, prenatal care, dysmorphic growth, preterm labor, recurrent pregnancy loss, infection, diabetes, postdates, normal labor, induction and augmentation, prolonged labor, fetal heart rate monitoring, routine postpartum and complications postpartum. A new chapter has been added that covers vaccination in pregnancy as well as other routine wellness recommendations. Now in its fully revised and expanded third edition, Obstetrics in Family Medicine reflects the significant changes that have occurred in the field since 2015. This book remains the definitive resource for meeting the needs of a wide range of primary care providers who provide direct or indirect care of patients of childbearing age. This book also appeals to nurse practitioners, physician assistants and nursing personnel working in the primary care setting. Additionally, this book serves as a useful guide for medical providers who intersect with pregnant, or possibly pregnant patients including emergency medicine physicians, surgeons, EMT's and paramedics. .

This volume covers the known details of all subtypes of occult spinal dysraphism in unprecedented detail. This 21 chapter invaluable resource begins with a deep dive into the history and embryology of occult spinal dysraphisms. Following this, subtypes of occult spinal dysraphism are thoroughly explored ??? of which include split cord malformations, tethered cord syndromes, adult presentations/outcomes of occult spinal dysraphism, cutaneous stigmata. Chapters will cover the clinical presentation, radiological features, and surgical nuances of each of the occult spinal dysraphisms. Throughout the book, expertly written text is supplemented by a number of high quality figures and tables, as well as a video documenting surgical treatment of type 1 split cord malformation. By focusing on each entity currently grouped within this topic as a separate chapter, the most up-to-date information will be provided to the reader, making Occult Spinal Dysraphism a must-have resource for students, practitioners and medical professionals involved in treating spinal dsyraphism.

This book provides cutting-edge information on the epidemiology, etiology and pathophysiology of several prevalent occupational and environmental skin diseases (OSD/ESD), with a particular focus on skin health safety issues, risk factors, preventive measures and recent advances in the management of these diseases. It also highlights recent discoveries and developments concerning novel therapeutic agents for inflammatory OSD, especially findings that are supported by clinical data and have the potential to transform conventional prophylactic and therapeutic approaches. For example, despite their increasing prevalence, the management of allergic skin diseases is sometimes challenging, mainly due to limited treatment choices. In several countries, steroids are the only treatment used. However, in cases of contraindications, adverse effects or unsatisfactory steroidal therapies, alternative treatments are indispensable. As such, an understanding of promising anti-allergic agents enhances allergy research and could eventually lead to novel alternative therapeutic and adjuvant remedies, which are of the utmost importance. This book offers a valuable resource for researchers, graduate students and practitioners in the field of public health in general, especially those working in environmental and occupational medicine, as well as physicians.

This book is a comprehensive guide to occupational factors of malignant diseases. It discusses potentially work-related malignancies, in the context of exposure assessment, specific clinical and pathological features of occupational cancer and biomarkers of exposure and disease. Epidemiological data about risk ratios of the cancer in question are reviewed for various occupations and with exposure to specific carcinogens, carcinogenic mechanisms, host susceptibility factors (genetic and other) and other environmental and life-style risk factors. Aspects such as surveillance of workers exposed to carcinogens, and strategies for prevention of occupational cancer are also discussed. Occupational Cancers is aimed at oncologists, pathologists, residents in training, clinical researchers, clinicians in occupational health, epidemiologists, pulmonologists, lawyers and public health officials.

This up-to-date review of the literature on the epidemiology and pathology of work-related cancers also includes sensitive diagnostic questionnaires and data on the risk ratios of differing cancers in relation to a variety of occupations and lifestyle factors.

"At the very beginning of the development of the profession of occupational therapy Anne Mosey put together some exciting concepts such as "A group is more than a collection of individuals. Members of a group are bonded together by their group identity and shared purposes which will be realised by interacting and working together" (Mosey 1973). Why Groups? What is it that actually makes group therapy an occupational therapists' choice of intervention when there are other methods available? Does one look at personal preference, or suitability in a particular clinical area which is related to curative factors for particular clients? It has to be a combination of both. "We use groups because they are a naturally occurring phenomenon, which are known to have good and bad effects on people." (Bundey, Cullen, Denshing et, al.1968). Fouché (2019) describes a group as part of a microcosm and states that "The way you interact with others in the outside world will be the same way in which you will act and treat others in the group or society and the same requirements. "(p.1) She also states that "groups present a small society and have the same ingredients as any community.""-- Provided by publisher.

This book provides occupational health (OH) professionals with a theoretical basis for addressing the ethical issues that they confront in their practice. There is often a lack of in-depth moral analysis of the issues that OH practitioners face on a daily basis. The ICOH Code of Ethics sets out the important principles that guide OH practice. This book builds on these core principles, starting from an application of moral theories in the OH context and illustrating how ethical conflicts could be resolved, by carrying out ethical analyses of several case studies. In this way, it aims to link ethical theory to OH practice.

The Occupational Outlook Handbook 2014-2015 is the most widely respected and used career reference available--and only JIST Publishing's version includes useful bonus content, including Personality-Career Quiz and a new Best OOH Jobs list. In JIST's 2014-2015 edition of the OOH features well written, interesting descriptions for more than 330 major jobs in the U.S., as well as summary information on additional jobs. For each job, the book discussed work tasks, job outlook through 2022, training and education needed, pay, work environment, similar occupations, and additional information sources. The book is packed with photos, charts, and practical, current information, which makes it invaluable for anyone doing career research, making career decisions, writing resumes, and preparing for interviews. This OOH includes another JIST Publishing exclusive: the Personality-Career Quiz, which matches readers to specific OOH jobs. The quiz is based on the six RIASEC personality types: realistic, investigative, artistic, social, enterprising, and conventional. A special section, How Educators, Counselors, Librarians, and Business Professionals can best use the OOH, is also included, JIST's version of the OOH also provides more current wage information than the online OOH provides.

Delivering good quality, safe and effective care -- Person-centredness and long term neurological conditions -- Theoretical basis -- Occupation and long term neurological conditions -- Identifying occupational performance enablers and deficits -- Occupational therapy intervention -- Using technology to support participation -- Living with a long term condition -- Planning for the future.

Perspectives of ageing / Anne McIntyre -- The social context of older people / Frances Reynolds and Kee Hean Lim -- Policy development and implications for occupational therapy practice / Margaret Gallagher -- Health conditions and active ageing / Melanie Manley [and others] -- The ageing body : body functions and structures : part 1 / Stephen Ashford and Anne McIntyre -- The ageing body : body functions and structures : part 2 / Linda Gnanasekaran -- Occupation and successful ageing : activity and participation / Anne McIntyre -- Environmental impacts, products and technology / Anita Atwal [and others].

"Occupational Therapy Evidence in Practice for Mental Health" provides students and practitioners with a textbook that both demonstrates and explains the application of evidence-based practice. The book contains case studies that clearly illustrate the ways in which theory, research and/or governmental guidelines can be used to inform clinical reasoning and practice. Each chapter addresses different areas of mental health and demonstrates how the occupational therapy process might be implemented for each individual and how available evidence can be used to inform this process as well as the therapist's reasoning and critical reflection. Content spans a wide range of occupational therapy practice with client cases representing a variety of diagnoses, ages and social and cultural backgrounds within an assortment of health or social care settings.

v. 1. 1000 multiple choice questions and referenced explanatory answers.

v. 1. 1200 multiple choice questions and referenced answers.

This book focuses on evidence-based occupational therapy in the care of older adults in different clinical settings, from home to acute hospital, from intensive care unit to rehabilitation centers and nursing homes. Occupational therapy has progressively developed as a new discipline aiming to improve the daily life of individuals of different ages, from children to older adults. The book first reviews the interaction between occupational therapy and geriatrics and then discusses in depth how occupational therapy interventions are applied in the community, in the acute hospital and in the nursing home. It highlights the key role of occupational therapy in the management of frail patients, including critically ill older patients and persons with dementia, and describes in detail how to maintain occupational therapy interventions across different settings to avoid the fragmentation of care. The ageing population requires new innovative approaches to improve the quality of life, and as such this book provides clinicians with handy, key information on how to implement occupational therapy in the daily clinical care of older adults based on the current scientific evidence.

Epidermolysis bullosa (EB) is the collective term for a heterogenous group of genetic skin disorders characterised by the formation of blisters and erosions on skin and mucous membranes.This book deals with early childhood motor and perceptual development, a particular challenge for children with extremely fragile skin. Going into functional treatment, it addresses rehabilitation of hands and feet in EB patients with fusions or contractures.The authors are occupational therapists with long-term experience in the management of EB patients. In an extraordinary holistic approach, they present a combination of paediatric and functional areas of treatment.Occupational therapy tools and interventions can help alleviate a number of accompanying complications and symptoms of EB, enhance self-care, and improve quality of life in general.Due to its practical approach, this book not only serves as a unique guide for doctors and health care professionals but is also comprehensible and useful for patients.

Part 1. Theoretical Concepts in Occupational Therapy : -- 1. Creative Ability: A Model for Individual and Group Occupational Therapy for Clients with Psychosocial Dysfunction / Patricia de Witt -- 2. The Relevance of Occupational Science to Occupational Therapy in the Field of Mental Health / Lana van Niekerk -- 3. Ethics, Human Rights and the Law in Mental Health Care Practice / Dain van der Reyden and Rosemary Crouch -- 4. Cultural Considerations in the Provision of an Occupational Therapy Service in Mental Health / Rosemary Crouch -- 5. Clinical Reasoning in Psychiatric Occupational Therapy / Vivyan Alers -- -- Part 2. Specific Issues in Occupational Therapy : -- 6. HIV/AIDS in Psychiatry and Issues Facing Occupational Therapists Regarding Practice: Moral and Ethical Dilemmas / Dain van der Reyden, Robin Joubert and Chantal Christopher -- 7. Forensic Psychiatry and Occupational Therapy / Michelle Moore -- 8. Acute Psychiatry and the Dynamic Short-Term Intervention of the Occupational Therapist / Catherine Shorten and Rosemary Crouch -- 9. Improving Health and Access to Health Services through Community-Based Rehabilitation / Stephanie Homer -- 10. Care, Treatment and Rehabilitation Programmes for Large Numbers of Long-Term Mental Health Care Users / Kobie Zietsman and Daleen Casteleijn -- 11. Auxiliary Staff in Mental Health Care: Requirements, Functions and Supervision / Dain van der Reyden -- 12. Vocational Rehabilitation in Psychiatry and Mental Health / Lyndsey Swart and Tania Buys -- 13. Psychiatric Occupational Therapy in the Corporate, Insurance and Medico-legal Sectors / Lee Randall -- 14. An Occupational Therapist's Perspective on Sexuality and Psychosocial Sexual Rehabilitation / Louise Fouché -- -- Part 3. Occupational Therapy with Children, Adolescents and Adults : -- 15. Early Intervention for Young Children at Risk for Developmental Mental Health Disorders / Kerry Wallace -- 16. Occupational Therapy Intervention with Children with Psychosocial Disorders / Vivyan Alers -- 17. Interdisciplinary Group Therapy with Children / Marita Rademeyer and Deirdre Niehaus -- 18. Specific Occupational Therapy Intervention with Adolescents / Louise Fouché and Lisa Wegner -- 19. Sensory Integration in Mental Health / Annamarie van Jaarsveld -- 20. Attention Deficit Hyperactive Disorder through a Person's Lifespan: Occupational Therapy to Enhance Executive and Social Functioning / Ray Anne Cook -- 21. Trauma and Its Effects on Children, Adolescents and Adults: The Role of the Occupational Therapist / Vivyan Alers -- 22. Post-traumatic Brain Injury: Handling Behavioural and Cognitive Changes / Sylvia Birkhead -- 23. Occupational Therapy for Anxiety, Somatic and Stressor-related Disorders / Madeleine Duncanand Claire Prowse -- 24. Occupational Therapy with Mood Disorders / Madeleine Duncan and Claire Prowse -- 25. The Treatment of Eating Disorders in Occupational Therapy / Rosemary Crouch and Vivyan Alers -- 26. Understanding Persons with Personality Disorders: Intervention in Occupational Therapy / Ann Nott -- 27. The Occupational Therapy Approach to the Management of Schizophrenia / Rosemary Crouch -- 28. Substance Use and Abuse: Intervention by a Multidisciplinary Approach Which Includes Occupational Therapy / Rosemary Crouch and Lisa Wegner -- 29. Gerontology, Psychiatry and Occupational Therapy / Susan Beukes.

"Highly visual and easy to navigate, OCT and OCT Angiography in Retinal Disorders is a concise, reliable reference for optical coherence tomography (OCT) and OCT angiography findings in both common and uncommon retinal disorders. Each chapter explores the prognostic features of OCT and OCTA scans along with additional diagnostic modalities for comparison and correlation. Where appropriate, longitudinal changes in response to treatment or natural history are also discussed. Includes hundreds of high-quality, striking images. Highlights the salient imaging features of the clinical entity or entities being discussed. Covers OCT technology, techniques, and scanning patterns . Provides concise, authoritative guidance on numerous key areas in retinal disease, including retinal vascular disease, inflammation, retinal degenerations and dystrophies, ocular trauma ocular tumors, and much more"-- Provided by publisher.

Optical coherence tomography angiography : understanding the basics / David R. Chow -- Optical coherence tomography angiography artifacts / Paulo Ricardo Chaves de Oliveira, Keyvan Koushan, and David R. Chow -- Current optical coherence tomography angiography clinical systems / Sumit Sharma and Peter K. Kaiser -- Optical coherence tomography angiography and neovascular age-related macular degeneration / Nicholas A. Iafe, Nopasak Phasukkijwatana, and David Sarraf -- Optical coherence tomography angiography and fibrotic choroidal neovascularization in age-related macular degeneration / Eric Souied and Alexandra Miere -- Nonneovascular age-related macular degeneration / Ricardo Noguera Louzada, Mark Lane, and Nadia K. Waheed -- Optical coherence tomography angiography and diabetic retinopathy / André Romano -- Optical coherence tomography angiography and arterial occlusions / Abtin Shahlaee, Carl D. Regillo, and Allen C. Ho -- Optical coherence tomography angiography in retinal venous occlusions / Mostafa Hanout, Paulo Ricardo Chaves de Oliveira, and Alan R. Berger -- Optical coherence tomography angiography and central serous chorioretinopathy / Wasim A. Samara, Carl D. Regillo, and Allen C. Ho -- Optical coherence tomography angiography in macular telangiectasia type 2 / Alain Gaudric and Valérie Krivosic -- Optical coherence tomography angiography and adult-onset foveomacular vitelliform dystrophy / Giuseppe Querques, Adriano Carnevali, Federico Corvi, Lea Querques, Eric Souied, and Francesco Bandello -- Optical coherence tomography angiography and high myopia / Taku Wakabayashi and Yasushi Ikuno -- Optical coherence tomography angiography and uveitis / Eduardo A. Novais, André Romano, and Rubens Belfort Jr. -- Optical coherence tomography angiography findings in ocular oncology and radiation retinopathy / Meghna V. Motiani, Colin A. McCannel, and Tara A. McCannel -- Optical coherence tomography angiography and glaucoma Gábor Holló -- Optical coherence tomography angiography and anterior segment vasculature / Christophe Baudouin, Stephanie Hayek, and Adil El Maftouhi -- The future of optical coherence tomography angiography / Emily D. Cole, Eric M. Moult, Eduardo A. Novais, James G. Fujimoto and Nadia K. Waheed -- Optical coherence tomography angiography rounds / David R. Chow.

Heidelberg spectralis optical coherence tomography angiography /Coscas, G., Lupidi, M., Coscas, F. -- Optical coherence tomography angiography using the optovue device / Huang, D., Jia, Y., Gao, S.S., Lumbroso, B., Rispoli, M. -- Swept-source optical coherence tomography Angio (Topcon Corp, Japan) : technology review / Stanga, P.E., Tsamis, E., Papayannis, A., Stringa, F., Cole, T., Jalil, A. -- ZEISS Angioplex pectral domain optical coherence tomography angiography : technical aspects / Rosenfeld, P.J., Durbin, M.K., Roisman, L., Zheng, F., Miller, A., Robbins, G., Karen, S., Gregori, G. -- Image analysis of optical coherence tomography angiography / Coscas, G., Lupidi, M., Coscas, F. -- Optical coherence tomography angiography in healthy subjects / Coscas, G., Lupidi, M., Coscas, F. -- Optical coherence tomography angiography of type 1 neovascularization in age-Related macular degeneration / Iafe, N., Phasukkijwatana, N., Sarraf, D. -- Optical coherence tomography angiography of type 2 neovascularization in age-related macular degeneration / Souied, E.H., El Ameen, A., Semoun, O., Querques, G., Cohen, S.Y. -- Optical coherence tomography angiography features of type 3 neovascularization in age-related macular degeneration / Querques, G., Miere, A., Souied, E.H. -- Optical coherence tomography angiography of retinal and macular diseases / Liang, M.C., Witkin, A.J. -- Optical coherence tomography angiography of tdiopathic polypoidal choroidal vasculopathy / Srour, M., Querques, G., Souied, E.H. -- Optical coherence tomography angiography study of choroidal neovascularization early response after treatment / Lumbroso, B., Rispoli, M., Savastano, M.C., Jia, Y., Tan, O., Huang, D. -- Optical coherence tomography angiography of fibrosis in age-related macular degeneration / Souied, E.H., Miere, A., Cohen, S.Y., Semoun, O., Querques, G. -- Optical coherence tomography angiography of dry age-related macular degeneration / Waheed, N.K., Moult, E.M., Fujimoto, J.G., Rosenfeld, P.J. -- Optical coherence Tomography Angiography of choroidal neovascularization secondary to pathologic myopia / Querques, G., Corvi, F., Querques, L., Souied, E.H., Bandello, F. -- Optical coherence tomography angiography of diabetic retinopathy / Bandello, F., Corbelli, E., Carnevali, A., Pierro, L., Querques, G. -- New findings in diabetic maculopathy and proliferative disease by swept-Source optical coherence tomography angiography / Stanga, P.E., Papayannis, A., Tsamis, E., Stringa, F., Cole, T., D'Soza, Y., Jalil, A. -- Optical coherence tomography angiography of retinal artery occlusion / Baumal, C.R. -- Optical coherence tomography angiography of retinal vein occlusion / Novais, E.A., Waheed, N.K. -- Optical coherence tomography angiography of deep capillary ischemia / Nemiroff, J., Phasukkijwatana, N., Sarraf, D. -- Optical coherence tomography angiography of macular telangiectasia type 2 / Roisman, L., Rosenfeld, P.J. -- Optical coherence tomography angiography in dystrophies / Battaglia Parodi, M., Pierro, L., Gagliardi, M., Lattanzio, R., Querques, G., Bandello, F. -- Swept-source optical coherence tomography angiography of paediatric macular diseases / Stanga, P.E., Papayannis, A., Tsamis, E., Chwiejczak, K., Stringa, F., Jalil, A., Cole, T., Biswas, S. -- Optical coherence tomography angiography of miscellaneous retinal disease / Pierro, L., Battaglia Parodi, M., Introini, U., Querques, G., Bandello, F.

This book provides readers with the most up-to-date practical information on optical coherence tomography (OCT) imaging in glaucoma. A key aim is to demonstrate how imaging results are interpreted and applied in clinical practice. To this end, many high-quality images are presented to document findings in patients with glaucoma, glaucoma suspects, and healthy subjects and to explain their clinical significance. The book is timely in that the role of OCT in the early diagnosis of glaucoma, the detection of disease progression, and the choice of management options has been advancing rapidly. OCT-based exploration of the segmented layer of the neural tissue and the deeper structures of the optic nerve, as well as OCT evaluation of the vascular network around the optic nerve head, facilitates understanding and assessment of the risk of glaucomatous damage. In explaining all aspects of the use of OCT in glaucoma, this book will be a rich source of information and guidance for practicing ophthalmologists, glaucoma specialists, and trainees.

"Whenever we envision a world without war, without prisons, without capitalism, we are producing speculative fiction. Organizers and activists envision, and try to create, such worlds all the time. Walidah Imarisha and adrienne maree brown have brought twenty of them together in the first anthology of short stories to explore the connections between radical speculative fiction and movements for social change. The visionary tales of Octavia's Brood span genres--sci-fi, fantasy, horror, magical realism--but all are united by an attempt to inject a healthy dose of imagination and innovation into our political practice and to try on new ways of understanding ourselves, the world around us, and all the selves and worlds that could be. The collection is rounded off with essays by Tananarive Due and Mumia Abu-Jamal, and a preface by Sheree Renee Thomas."--Amazon.com.

This comprehensive book focuses on eyelid, lacrimal and orbital lesions, covering a wide variety of common and rare diseases and correlating their clinical, radiological and pathological aspects. It presents a large number of illustrative cases, with a discussion of the clinical history, examination, the imaging and pathology findings , differential diagnosis and management along with a take home message for each. Further, it offers clear guidance on the diagnosis and management of orbital and adnexal lesions. This book is a valuable learning tool for residents and trainee fellows in ophthalmology, as well as for trainees in radiology and pathology. It is also relevant to young ophthalmic plastic and reconstructive surgeons, practicing ophthalmologists, radiologists, and pathologists.

This book a conjoint effort of ocular oncologists, general oncologists, and pathologists is a comprehensive source of authoritative information on the subject of ocular and adnexal lymphoma. It covers all aspects, including clinical features, classification, epidemiology, diagnostic evaluation, biopsy techniques, histology and molecular pathology, staging procedures, and treatment methods. Detailed information is provided on primary vitreoretinal and adnexal lymphomas and chapters are also included on rare variants such as T cell lymphoma and reactive lymphoid hyperplasia of the ocular adnexa. The emphasis throughout is on easy readability, and the layout ensures rapid retrieval of information. In order to convey fundamental concepts, numerous tables, clinical photographs, histopathologic microphotographs, and imaging studies (fluorescein and indocyanine angiograms, ultrasonograms, CT scans, and MR images) are included.

This book meets the growing demand among ophthalmologists, optometrists and orthoptists, in training and in practice, as well as visual neuroscientists, to have a clear, succinct and well-written textbook to objectively cover the subject of ocular and visual physiology. Ocular and visual physiology is a core knowledge component for these disciplines, and yet is often difficult to understand. However, this book clearly conveys the simple elegance of the relationship between structure and function that is the hallmark of understanding the physiology of the eye and visual system. Ocular and Visual Physiology - Clinical Application is essential reading for any one hoping to have a clear understanding of the subject. Students will find it a great resource to pass their exams. Each of the chapters has been independently reviewed and edited by an expert in the field with a clinical or visual scientific academic background. The text is based on the latest publications in peer-reviewed journals that are closely referenced within the body of the text.

Ocular Emergency is a systematic, symptom based reference book for clinical practice guidance. This book aims to provide the most thorough knowledge and standard process to clinical practitioners, such as the nurses, medical students, residents, fellows and even ophthalmologists, to help them make the most appropriate decision on the management of patients who have suffered from urgent ocular conditions. The first three chapters provide the audiences general information of ocular emergency and the emergency room (ER), which will help them generate a clinical thinking. The following four chapters are symptom based discussion of common complaints of ocular emergency. These chapters contain almost all the symptoms the audiences will meet in the ER and covers hundreds of diseases the audiences may or may not think of which fits the symptom. They will help the readers to make the right diagnose and offer the best advice or treatment to the patients. The last two chapters provide the audiences the information of most urgent ocular traumas. For each disease, definition, etiology, clinical presentations and signs, treatment and typical clinical case with pictures or illustrative figures will be provided. In addition, each chapter will be provided with an algorithym(s) for differential diagnosis and treatment as a summary of the chapter. Hopefully this book may help the clinical practitioners to be fully prepared for any challenge of ocular emergency cases.

Ocular infections remain an important cause of ocular morbidity and loss of vision, yet many are preventable or curable. Early diagnosis and prompt treatment help in the control of such infectious disorders and the prevention of blindness. There are many infectious diseases of the eye and adnexa, and knowledge of their diagnosis and management is essential to an optimal therapeutic outcome. This book provides the practitioner with the important information required to ensure appropriate diagnosis and management of ocular infectious diseases. Specific clinical signs and symptoms are outlined, and the role of specific diagnostic tests, including molecular biology techniques, is explained. All of the most common microorganisms are considered and current knowledge on the antimicrobial therapy of ocular infections is clearly summarized. Ocular Infections will be a great help to physicians as a guide to the care of patients with ocular infectious diseases.

Ocular melanoma: advances in diagnostic and therapeutic strategies / Timothy G. Murray & H. Culver Boldt -- Laboratory discoveries in uveal melanoma / Aart G. Jochemsen & Martine J. Jager --Incidence, prevalence and epidemiology of ocular melanoma / Tero Kivelä -- Clinical features and diagnosis / Katrina Mears & H. Culver Boldt -- Diagnostic imaging in ocular melanoma / Timothy G. Murray, Fiona J. Ehlies, Andrea Wildner & Aaron S. Gold -- Genetics of ocular melanoma and implications for patient risk / Bertil Damato & Sarah E. Coupland -- Biopsy approaches and testing strategies for genomic prognostication / Carlos A. Medina & Arun D. Singh -- Preoperative clinical evaluation and imaging for uveal melanoma / Sohpie Piperno-Neumann, Vincent Servois, Pascale Mariani & Laurence Desjardins -- Regional anesthesia for surgical management of ocular melanoma / Jacqueline Tutiven & Michael Vigoda -- Enucleation surgery in advanced ocular disease / Daniel Gologorsky & Timothy G. Murray -- Brachytherapy for uveal melanoma / Samuel K. Houston 3rd, H. Culver Boldt & Timothy G. Murray -- Charged particle radiotherapy for ocular melanoma / Ivana K. Kim, Anne Marie Lane, Helen A. Shih & Evangelos S. Gragoudas -- Adjunctive treatment strategies for high-risk ocular melanoma / Sapna P. Patel & Dan S. Gombos -- Treatment strategies for clinically detectable metastatic uveal melanoma / Aakanksha Prasad Asija, Makoto Yoshida & Takami Sato -- Surveillance for early detection of metastatic ocular melanoma following definitive local therapy / Jasmine H. Francis, Tero Kivelä & Richard D. Carvajal -- Ophthalmic screening for postradiotherapy complications: implications for treatment and visual outcomes / Samuel K. Houston 3rd, Nisha Shah & Timothy G. Murray -- Collaborative Ocular Melanoma Study: overview of outcomes / Barbara S. Hawkins -- Surgical management of radiation-related complications / Samuel K. Houstin 3rd & Timothy G. Murray -- Visual rehabilitation for ocular melanoma / Aaron S. Gold, Azeema Latiff & Timothy G. Murray -- Index.

This atlas covers all aspects of retina, retinal pigment epithelium, and choroidal tumors, as well as other simulating lesions of intraocular tumors and paraneoplastic syndromes. Each chapter features numerous high-quality pictures based on multimodal imaging, including color fundus photography, fundus autofluorescence, optical coherence tomography, ultrasonography, ultra-widefield imaging, and fundus angiography. Designed to assist in the diagnosis and treatment of posterior segment intraocular tumors and simulating lesions, this book is intended for ocular oncologists, retina specialists, general ophthalmologists, residents and retina fellows. Ocular Oncology atlas is part of the series Retina Atlas, which provides global perspectives on vitreoretinal diseases, covering imaging basics, retinal vascular disease, macular disorders, ocular inflammatory and infectious disorders, retinal degeneration, surgical retina, ocular oncology, pediatric retina and trauma. Retina Atlas consists of 9 volumes and about 100 chapters, presenting validated and comprehensive information on retinal disorders.

This book concentrates on ocular oncology covering the latest advances in both adult and pediatric oncology. The topics covered are: retinoblastoma, melanoma, graft vs. host disease, squamous cell neoplasia, intraocular lymphoma, coats disease, and choroidal hemangioma. Each chapter is written by an expert in the field and covers the most recent developments in management. As part of the series "Current Practices in ophthalmology" this volume is meant for residents, fellows-in-training, generalist ophthalmologists and specialists alike.

Basic principles of pathology -- Congenital anomalies -- Nongranulomatous inflammation : uveitis, endophthalmitis, and sequelae -- Granulomatous inflammation -- Surgical and nonsurgical trauma -- Skin and lacrimal drainage system -- Conjunctiva -- Cornea and sclera -- Uvea -- Lens -- Neural (sensory) retina -- Vitreous -- Optic nerve -- Orbit -- Diabetes mellitus -- Glaucoma -- Ocular melanocytic tumors -- Retinoblastoma and stimulating lesions.

Challenges in ocular pharmacokinetics, pharmacodynamics, and toxicology / Brian C. Gilger -- Selection of appropriate animal models in ocular research : ocular anatomy and physiology of common animal models / Brian C. Gilger, Eva Abarca, and Jacklyn H. Salmon -- Challenges and strategies in drug residue measurement (bioanalysis) of ocular tissues / Poonam R. Velagaleti and Michael H. Buonarati -- Chemistry, manufacturing, and control of ophthalmic formulations / Malay Ghosh and Imran Ahmed -- ADME and ocular therapeutics : retina / Cornelis J. Van der Schyf, Samuel D. Crish, Christine Crish, Denise Inman, and Werner J. Geldenhuys -- Compositions, formulation, pharmacology, pharmacokinetics, and toxicity of topical, periocular, and intravitreal ophthalmic drugs / Kishore Cholkar, Aswani Dutt Vadlapudi, Hoang M. Trinh, and Ashim K. Mitra -- Sustained-release ocular drug delivery systems : bench to bedside development / Susan S. Lee, Michael R. Robinson, and Scott M. Whitcup -- Ophthalmic examination as it pertains to general ocular toxicology : basic and advanced techniques and species-associated findings / David A. Wilkie -- Study design and methodologies for evaluation of anti-glaucoma drugs / Paul E. Miller -- Study design and methodologies for study of ocular medical devices / Joseph W. Carraway and Elaine M. Daniel -- Methodologies for microscopic characterization of ocular toxicity / Leandro B.C. Teixeira and James A. Render -- Nanoparticles for drug and gene delivery in treating diseases of the eye / Shreya S. Kulkarni and Uday B. Kompella.

This book focuses on the concept of ocular rigidity, the biomechanical properties and hydrodynamics of the human eye. The basics of anatomy and physiology are explored and the relevant data for the clinician are emphasized throughout the book. The engineering aspects as well as the clinical interpretation are presented to provide context. Ocular Rigidity, Biomechanics and Hydrodynamics of the Eye summarises recent evidence on ocular rigidity, but also provides a complete presentation of the data so far. The authors have recently worked on ocular rigidity corneal and globe biomechanics and hydrodynamics and the new, up-to-date data on the subject are highlighted in each chapter. The aim is to provide the framework or the understanding of these parameters and to determine their relevance in health and disease. This book will be an essential read for all practicing ophthalmologists looking to gain a more in-depth understanding of this interesting area of research particularly in refractive surgery and glaucoma.

"Offering concise, easy-access information for the most common ocular problems, Ocular Therapeutics Handbook: A Clinical Manual is a proven, practical resource for optometrists, nurses, and primary care physicians. A consistent outline format and numerous algorithms make vital information easy to retrieve, while a problem-oriented approach provides a real-world perspective and helps build critical thinking skills. The revised 4th Edition includes an accompanying eBook that contains all of the content in the book, plus additional clinical photographs, illustrations, and surgical and procedural videos."--Publisher

Contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. Key topics covered include the anatomy and physiology of the eye, biology of ocular transporters and receptors and techniques in their characterization, transporters and receptors in the anterior and posterior segment in the eye, and transporter-metabolism interplay in the eye.

The book covers practically all tumors of eye and adnexa. Chapters are contributed by well-established ocular oncologists of India. It describes retinoblastoma, malignant melanoma and lymphoma in some detail while covering tumors of lids and conjunctiva briefly. Separate chapters are devoted to the pathology of retinoblastoma, genetics of retinoblastoma and malignant melanoma. Each chapter is profusely illustrated. The book provides state-of-the-art knowledge needed to diagnose ocular cancers in the early stage and to treat them effectively. The book meets the curriculum of postgraduate studies of the Indian Universities. It will be very useful for students who are preparing for MD, MS, DNB and FRCS examinations. The book will assist practicing ophthalmologists in early diagnosis and treatment of ocular tumors.

This book provides a comprehensive account of the pathogenesis, clinical features, and management of ocular vascular occlusive disorders, with the focus very much on the scientific evidence. This offers a sound basis for addressing the many controversies that surround these disorders, which collectively constitute the most common cause of visual impairment or blindness. The book is divided into two sections, the first of which addresses the basic science and encompasses vascular anatomy, blood supply and flow, and retinal tolerance time to acute ischemia. The second, clinical, section covers the presentation, clinical features, diagnosis, and treatment of the full range of vascular occlusive disorders of the retina, the choroid, the anterior segment of the eye, ophthalmic manifestations of carotid artery disease and the optic nerve. ℗ℓ In writing Ocular Vascular Occlusive Disorders, the author has drawn upon more than 55 years of experience in basic and clinical research. The book will be an invaluable source of information for general ophthalmologists, and particularly for retina specialists, neuro-ophthalmologists, and researchers. It is hoped that it will go far in rectifying the lack of in-depth scientific understanding that is the source of many misapprehensions and debates.

This comprehensive text covers both core and advanced principles within oculofacial, orbital, and lacrimal surgery with extensive detail not found in any other current book on the subject. Richly illustrated with hundreds of images, Oculofacial, Orbital, and Lacrimal Surgery: A Compendium is written and edited by international leaders in fields spanning ophthalmology, otolaryngology, oral and maxillofacial surgery, and plastic surgery. Covering topics such as embryology, anatomy, and physiology of the lacrimal system, imaging for orbital diseases and thyroid-related ophthalmology, and flap geometry and planning, this book is an excellent resource for those in training, as well as seasoned clinicians looking to stay current. This book is divided into five sections: Eyelid, Oculofacial, Lacrimal, Orbit, and Socket, with each section containing detailed chapters addressing evaluation, imaging, and various surgical approaches and management. Designed to not only provide an anatomical and surgical guide for all three types of surgeries, but to help physicians avoid mistakes and correct complications of patients referred to them, Oculofacial, Orbital, and Lacrimal Surgery: A Compendium is the definitive, authoritative reference on this complex field.

Oculoplastic Surgery: A Practical Guide to Common Disorders provides guidance on various clinical approaches for treating oculoplastic disorders as well as ocular trauma. In addition, highly illustrated and informative chapters examine the interaction between oculoplasty, ophthalmic sub-specialties (pediatrics, cataract, refractive, neuro, glaucoma) and other clinical areas including ENT, maxillofacial, dermatology, general plastic surgery and psychiatry. Consultants, surgeons, trainees and health professionals from all the specialties and sub-specialties related to oculoplasty, will find this book to be an indispensable resource for further developing skills and knowledge in the field of oculoplastic surgery.

This book is a concise, easy-to-use multi-choice question and answer resource in oculoplasty for ophthalmologists undertaking exams in this sub-specialty. Each chapter contains a short didactic summary of the topic followed by MCQs and answers. References to the full-text book Oculoplastic Surgery: A Practical Guide to Common Disorders are also included in the answer section of each chapter. This unique format allows readers to dip into MCQs to practice for exams while also providing clear references of where to find chapters from a larger text. This book includes MCQs that examine the interaction between oculoplasty, ophthalmic sub-specialties (pediatrics, cataract, refractive, neuro, glaucoma) and other clinical areas including ENT, maxillofacial, dermatology, general plastic surgery and psychiatry. Consultants, surgeons and trainees from all ophthalmic specialties and sub-specialties will find this book to be an indispensable resource for exam revision in oculoplasty.

This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume explores interdisciplinary research on invertebrate and vertebrate models of odor memory and perception, as well as human odor memory and perception. This book brings together a collection of authors that cut across model systems, techniques, levels of analysis and questions to highlight important and exciting advances in the area of olfactory memory and perception.

Chapter One: Genome mining and sequence analysis of chemosensory soluble proteins in arthropods -- Chapter Two: Reconstructing protein-coding sequences from ancient DNA -- Chapter Three: Bioinformatic, genomic and evolutionary analysis of genes: A case study in dipteran CSPs -- Chapter Four: Proteomics of arthropod soluble olfactory proteins -- Chapter Five: Analysis of post-translational modifications in soluble proteins involved in chemical communication from mammals and insects -- Chapter Six: Bacterial expression and purification of vertebrate odorant-binding proteins -- Chapter Seven: Structure of odorant binding proteins and chemosensory proteins determined by X-ray crystallography -- Chapter Eight: Solution structure of insect CSP and OBPs by NMR -- Chapter Nine: Stability of OBPs -- Chapter Ten: Ligand-binding assays with OBPs and CSPs -- Chapter Eleven: Fine structure immunocytochemistry—An important tool for research on odorant-binding proteins -- Chapter Twelve: Effect of OBPs on the response of olfactory receptors -- Chapter Thirteen: Site-directed mutagenesis of odorant-binding proteins -- Chapter Fourteen: Silencing of OBP genes: Generation of loss-of-function mutants of PBP by genome editing -- Chapter Fifteen: Electrochemical biosensing with odorant binding proteins: Chapter Sixteen - Electronic biosensors based on graphene FETs -- Chapter Seventeen: Electronic biosensors based on EGOFETs -- Chapter Eighteen: Gravimetric biosensors -- Chapter Nineteen: Plasmonic biosensors relying on biomolecular conformational changes: Case of odorant binding proteins.

Gastrointestinal Tract Endoscopic and Tissue Processing Techniques and Normal Histology -- Screening and Surveillance Guidelines in Gastroenterology -- Diagnostic Cytology of the Gastrointestinal Tract -- Infectious Disorders of the Gastrointestinal Tract -- Manifestations of Immunodeficiency in the Gastrointestinal Tract -- Systemic Illnesses Involving the Gastrointestinal Tract -- Neuromuscular Disorders of the Gastrointestinal Tract -- Congenital and Developmental Disorders of the Gastrointestinal Tract -- Enteropathies Associated with Chronic Diarrhea and Malabsorption in Childhood -- Vascular Disorders of the Gastrointestinal Tract -- Autoimmune Disorders of the Gastrointestinal Tract -- Drug-Induced Disorders of the Gastrointestinal Tract -- Algorithmic Approach to Diagnosis of Inflammatory Disorders of the Gastrointestinal Tract -- Inflammatory Disorders of the Esophagus -- Inflammatory Disorders of the Stomach -- Inflammatory Disorders of the Small Intestine -- Inflammatory Disorders of the Large Intestine -- Inflammatory Disorders of the Appendix -- Polyps of the Esophagus -- Polyps of the Stomach -- Polyps of the Small Intestine -- Polyps of the Large Intestine -- Molecular Diagnostics of Tubal Gut Neoplasms -- Epithelial Neoplasms of the Esophagus -- Epithelial Neoplasms of the Stomach -- Epithelial Neoplasms of the Small Intestine -- Epithelial Neoplasms of the Large Intestine -- Epithelial Neoplasms of the Appendix -- Neuroendocrine Tumors of the Gastrointestinal and Pancreatobiliary Tracts -- Mesenchymal Tumors of the Gastrointestinal Tract -- Hematolymphoid Tumors of the Gastrointestinal Tract, Hepatobiliary Tract, and Pancreas -- Inflammatory and Neoplastic Disorders of the Anal Canal -- Gallbladder, Extrahepatic Biliary Tract, and Pancreas Tissue Processing Techniques and Normal Histology -- Molecular Genetics of Pancreatobiliary Neoplasms -- Diagnostic Cytology of the Biliary Tract and Pancreas -- Developmental Disorders of the Gallbladder, Extrahepatic Biliary Tract, and Pancreas -- Infectious and Inflammatory Disorders of the Gallbladder and Extrahepatic Biliary Tract -- Benign and Malignant Tumors of the Gallbladder and Extrahepatic Biliary Tract -- Inflammatory and Other Nonneoplastic Disorders of the Pancreas -- Tumors of the Pancreas -- Tumors of Major and Minor Ampulla -- Algorithmic Approach to Diagnosis of Liver Disorders -- Liver Tissue Processing and Normal Histology -- Molecular Pathogenesis and Diagnostics of Hepatocellular Tumors -- Diagnostic Cytology of the Liver -- Acute and Chronic Infectious Hepatitis -- Autoimmune and Chronic Cholestatic Disorders of the Liver -- Toxin- and Drug-Induced Disorders of the Liver -- Fatty Liver Disease -- Cirrhosis -- Vascular Disorders of the Liver -- Pathology of Liver and Hematopoietic Stem Cell Transplantation -- Liver Pathology in Pregnancy -- Inherited Metabolic and Developmental Disorders of the Pediatric and Adult Liver -- Benign and Malignant Tumors of the Liver.

1. OPCAB made in Japan, evidence on off-pump coronary artery bypass grafting from Japan -- 2. Statistics of OPCAB in Japan -- 3. Evidence in OPCAB, critical appraisal of recent RCT based on CABG in Japen -- 4. Indication and safe strategy -- 5. Approach -- 6. Intraoperative management and anesthesia -- 7. Controversy, volume load vs. vasopressor -- 8. Urgent pump conversion, when does it occur and how can we prevent it? -- 9. Exposure -- 10. Stabilization -- 11. Securing the distal anastomosis site, coronary artery occlusion, shunt, and blower -- 12. Graft planning -- 13. Controversy, composite grafts versus individual grafts -- 14. Harvesting, tip and pitfalls -- 15. Graft-coronary anastomosis in off-pump CABG -- 16. Coronary endarterectomy and long onlay-patch grafting -- 17. OPCAB proximal -- 18. Intraoperative graft assessment OPCAB made in Japan -- 19. Stroke -- 20. Patient management OPCAB -- 21. Redo operation -- 22. Combined surgery (TAA, AAA, or cancer) concomitant or staged surgeries? -- 23. Difficult heart -- 24. Difficult corionary OPCAB made in Japan -- 25. Off-pump CABG for patients with end-stage renal failure -- 26. How do we teach off-pump surgery to the next generation? -- 27. Hybrid approach (OPCAB+PCI/TAVI/Ddebranching TEVAR) -- 28. Robotic surgery -- 29. OPCAB combined regenerative surgery -- Erratum -- Index.

This book is based on a review of the closed claims from the Oral and Maxillofacial Surgery Insurance Company (OMSNIC). Themes and trends that have been identified through review of these claims assisted in recognizing multiple causes of anesthesia related complications. This allowed the development of a presentation on the prevention, recognition and management of office based anesthesia complications to be delivered over 10 years to thousands of oral and maxillofacial surgeons in an attempt to reduce the incidence of future complications. This text provides detailed methods to allow the oral and maxillofacial surgeon, anesthetist and anesthesiologist to risk stratify patients as well as prevent, recognize and manage the most common anesthesia related complications. Additionally, it describes how to run an ideal Advanced Cardiac Life Support (ACLS) driven megacode, identify differences in pediatric anesthesia and ideally manage opioid needs of the oral and maxillofacial surgery patient. Office Based Anesthesia Complications is based on the most common anesthesia related complications that have been documented over more than 20 years of data collection for Oral and Maxillofacial Surgery.

With a new foreword by Nora Volkow, Director of the National Institute on Drug Abuse, this second edition of Office-Based Buprenorphine Treatment of Opioid Use Disorder provides updated information on evidence-based treatment for opioid use disorder (OUD)-an increasingly important topic as the epidemic of opioid misuse and overdose deaths grows in the United States. Bulleted clinical pearls at the end of each chapter, as well as specific clinical recommendations and detailed case discussions throughout, make it easier for readers to retain knowledge and integrate it into their clinical practice. The guide also features sample documentation and scales, including a treatment contract and a patient consent, that can be used to model documents in practice. This new edition of Office-Based Buprenorphine Treatment has been updated to reflect DSM-5 language, and two additional chapters have been included: one that addresses other pharmacotherapies useful in treating OUD, including methadone and naltrexone, and another that discusses OUD treatment specifically with regard to women's health and pregnancy. A discussion of the Comprehensive Addiction and Recovery Act (CARA). Advice for working with Alcoholics Anonymous and Narcotics Anonymous. A discussion on integrating buprenorphine into residential and inpatient opioid treatment programs. -- Publisher.

Recent trends in medicine have pushed many gynecologic procedures to the outpatient setting, whether in-office, in small medical ambulatory surgery centers, or in procedure rooms. Office-Based Gynecologic Surgical Procedures covers both basic and advanced procedures, from biopsy and saline ultrasound to cystoscopy. It answers the "How?", "What?", and "When?" of setting up, preparing for, and confidently performing office procedures. While appropriate training and certification in these procedures such as cystoscopy and hysteroscopy is needed, this book is an excellent resource for advice and tips on how to safely transition from the technique used in the operating room. It also provides the necessary algorithms and in-depth instructions pertinent to performing these types of procedures effectively in the office setting. A chapter on patient safety in the office is also included. Office-Based Gynecologic Surgical Procedures is ideal for established OBGYNs in practice who want to expand their range of procedures offered in-office, fellows in Women's Health, advanced nurse practitioners, recent OBGYN residency graduates, and family medicine physicians eager to familiarize themselves with women's health procedures.

This book provides a detailed description of laryngeal procedures performed under topical anesthesia in an office setting. The last two decades have witnessed a major evolution in laryngology practice toward office-based surgery, thus reducing the risk of general anesthesia and containing healthcare costs while also hastening recovery rates from the time of diagnosis. Beginning with a comprehensive review of the anatomy and physiology of phonation, the book then provides systematic assessment of patients with voice dysfunction secondary to structural and functional laryngeal disorders. It offers detailed instructions on patient selection, safety, tolerance, and proper administration of topical anesthesia. The book supplies detailed descriptions of the various surgical techniques commonly used in office-based laryngeal surgery using colored illustrations, photographs and videos. Different surgical approaches are presented including transcervical, transnasal and per-oral techniques. The book also supplies a thorough review of the literature on the current status of the most commonly performed office-based laryngeal surgeries including patient care, surgical outcome, and complications. Office-Based Laryngeal Surgery help laryngologists operating on awake patients in an office setting to be both well-equipped and well-informed.

This book is a comprehensive, step-by-step guide to maxillofacial surgical procedures typically performed in an office setting. It comprises three sections, the first of which provides an overview of general and basic perioperative topics such as medical and facial assessment, laboratory indications, local anesthesia, and oral and parenteral sedation. In the second section, a wide range of dentoalveolar procedures are described in detail. The final section is devoted to maxillofacial cosmetic procedures. Here, readers will find stepwise guidance on scar revision, chemical peel, laser resurfacing, dermabrasion, use of neuromodulators and fillers, neck procedures, blepharoplasty, and hair transplant surgery. The book is written by acknowledged experts and is multi-institutional and multispecialty based. It will meet the needs of multiple surgical professionals, including oral and maxillofacial surgeons, plastic surgeons, otolaryngologists, cosmetic surgeons, dentists, and medical and dental students. Health care providers will also be able to use the book as a resource to expand their knowledge on common maxillofacial surgical procedures.

This case-based guide covers 100 gynecologic problems commonly encountered in office practice settings, from the simple to the complex. It encourages evidence-based care and incorporates up-to-date guidance on evaluation and management in office practice. Clinical problems are discussed in a clear, case-based format. The book integrates current guidelines and recommendations, supplemented with carefully-researched and vetted expert opinion for situations for which no guidelines exist. Each gynecologic problem is assessed through a brief case presentation followed by an in-depth discussion with visual aids. Question and answer sections feature teaching points. Cases and discussions are detailed enough to guide practice, yet remain focused and concise, with each case designed to be read in the time available when seeing a patient in clinical practice. An invaluable reference guide for gynecologists, family physicians, internal medicine providers, and other women's health care providers who offer office-based gynecologic care.

Includes 1958-<1972> Annual report of the director of the Pan American Sanitary Bureau; 1959-<1991> Basic documents of the Pan American Health Organization.

"For nearly 40 years, Oh's Intensive Care Manual has been the quick reference of choice for ICU physicians at all levels of experience. The revised 8th edition maintains this tradition of excellence, providing fast access to practical information needed every day in today's intensive care unit. This bestselling manual covers all aspects of intensive care in sufficient detail for daily practice while keeping you up to date with the latest innovations in the field"--Publisher's description.

Whether you're a newcomer to the ICU or a seasoned practitioner, Oh's Intensive Care Manual delivers the practical, expert answers you need to manage the conditions you see every day in the intensive care unit. This highly esteemed, bestselling medical reference book presents comprehensive detail on each topic, while maintaining a succinct, accessible style so this information can be seamlessly incorporated into your daily practice. Access everything you need to know about disease processes and their management during the course of ICU rotations. Gain valuable insight into the consensus of practice and standard of ICU care as followed in the UK, Europe, India, and Australia. Take advantage of expert advice on practical issues that will be encountered on a day-to-day basis in the ICU, as well as common pitfalls in treatment and management emphasized in each chapter.

This book compiles the fundamental advances resulting from of oil-palm genome and transcriptome sequencing, and describes the challenges faced and strategies applied in sequencing, assembling and annotating oil palm genome sequences. The availability of genome and transcriptome data has made the mining of a high number of new molecular markers useful for genetic diversity as well as marker-trait association studies and the book presents high-throughput genotyping platforms, which allow the detection of QTL regions associated with interesting oil palm traits such as oil unsaturation and yield components using classical genetic and association mapping approaches. Lastly, it also presents the discovery of major genes governing economically important traits of the oil palm. Covering the history of oil palm expansion, classical and molecular cytogenetics, improvements based on wild and advanced genetic materials, and the science of oil palm breeding, the book is a valuable resource for scientists involved in plant genetic research.

Oilseeds offer a plethora of opportunities for the food and feed industry, thanks to their high oil and protein content . Their phytonutrients and functional components have attracted the interest of researchers, leading to the development of functional foods. This book gathers the latest scientific information on the nutrients, phytonutrients and health benefits as well as the adverse effects of consuming various conventional and non-conventional oilseeds. In addition, each chapter includes a section comprehensively explaining the use of oilseeds in functional bakery, dairy, and other food products. Given its scope, the book is a valuable resource for students, researchers, nutritionists, food scientists and technologists, and for anyone involved in product development based on oilseed and its components.

Animal evolution has always been at the core of Biology, but even today many fundamental questions remain open. The field of animal 'evo-devo' is leveraging recent technical and conceptual advances in development, paleontology, genomics and transcriptomics to propose radically different answers to traditional evolutionary controversies. This book is divided into four parts, each of which approaches animal evolution from a different perspective. The first part (chapters 2 and 3) investigates how new sources of evidence have changed conventional views of animal origins, while the second (chapters 4-8) addresses the connection between embryogenesis and evolution, and the genesis of cellular, tissue and morphological diversity. The third part (chapters 9 and 10) investigates how big data in molecular biology is transforming our understanding of the mechanisms governing morphological change in animals. In closing, the fourth part (chapters 11-13) explores new theoretical and conceptual approaches to animal evolution. 'Old questions and young approaches to animal evolution' offers a comprehensive and updated view of animal evolutionary biology that will serve both as a first step into this fascinating field for students and university educators, and as a review of complementary approaches for researchers.

Evolution gave rise to a prominent insect diversity at every level of ecological niche. Since then, hordes of insects have threatened human and cattle health as well as most of all green lands and agricultural crops. Now, the insect problem expands from many mutant forms of yellow dengue fever mosquitoes to highly-resistant larvae of most all various phytophageous species. The tremendous expansion of insect pests is due not only to an increasing resistance capacity to insecticides, but also to a strong capacity for adapting to different climate and environmental changes, including global warming. Obviously insects display a number of sophisticated systems to build an extremely efficient organism to survive in a changing world. In many species, one pheromone molecule is enough to trigger mating behavior. Therefore, insects have become crucial models not only for evolutionary studies, but also for understanding specific mechanisms underlying sensory-based behaviors. Most of insect species such as ants, beetles, cockroaches, locusts, moths and mosquitoes largely rely on olfactory cues to explore the environment and find conspecifics and food resources. A conglomerate of renowned international scientific experts is gathered to expose the insect problem on the various continents of the planet and propose an alternative to the use of toxic Olfactory Concepts of Insect Control-Alternative to Insecticides. Sex pheromones, specific chemical signals necessary for reproduction, and pheromone detection in insects are described with full details of the olfactory mechanisms in the antennae and higher centers in the brain. Thus, new synthetic pheromones and/or plant odors with specific molecular target sites in the insect olfactory system are proposed for sustainable development in agricultural and entomological industries. Disrupting insect pheromone channels and plant odor detection mechanisms is solemnly envisioned as a unique way to control invasive insect pest species while p reserving human and environment safety.

Most of all insect species respond to odor messages they exchange consciously. This is due to the existence of thousands of olfactory sensilla covering the antennal branches and thousands of nerve cells that will transmit the odor signal towards specific parts of the insect brain. Pheromones, pheromone regulatory pathways, pheromone-sensitive nerve cells, pheromone receptors and pheromone-binding proteins appear on this volume 2 as a prerequisite not only for fundamental knowledge in olfactory processes but also for applied research and insect control. The pheromone or olfactory concepts, exposed here in nocturnal species of moths, mainly deal with the phenomenal expansion of some specific insects, invasive pest species that have severe impacts on agriculture and/or human health. However, the olfactory concepts exposed on the whole book must be brought further, before the shrinkage of some other more beneficial species such as the honeybees. Like many other species (butterflies, crickets, ladybugs and other flying insects), the bees are disappearing or show signs of a fast and significant decline in hive population, as an example of the serious decline of flora and fauna due to our industrialized agriculture. In this no-choice situation, new concepts of pest control alternative to insecticides are required to stop the serious general disappearing of insects that are pollinators of flowers but also important ecological factors (e.g. as food sources or material converters). The present situation is very alarming for a nature at risk of losing a biodiversity and the ecological equilibrium that it has taken so long to build. We belong to the Quaternary (fourth) geological era, the "Age of Mammals", the Cenozoic era of evolution that describes 60 My, from the birth of the flower and the bee to the modern days. In a close future, Men of the current time period, i.e the 21st century, may soon enter a new historical era, which may lead to its own extinction. Would this be the price to pay to preserve or rebuild those interactions so crucial for the life on earth?

Despite the best efforts of many and despite landmark discoveries and experimental ingenuity, challenges in the pursuit of research related to olfactory receptors (ORs) continue to exist. In Olfactory Receptors: Methods and Protocols, experts in the field contribute chapters that serve to address these challenges. The volume consists of several sections: knowledge dissemination of ORs, theoretical assessments of OR structure and function, as well as development and use of expression systems and experimental functional analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Concise and practical, Olfactory Receptors: Methods and Protocols seeks to aid researchers in furthering the knowledge of olfaction and moving us ever closer to the thrilling discoveries that will follow.

The book provides an overview of bio-manufacturing techniques for the production, purification, characterization and modification of chito/chitin oligosaccharides and their monomers. In addition, it explores potential applications in the food, biomedical and agricultural industry on the basis of their bioactivities and biomaterial properties. Lastly, it shares a range of cutting-edge insights to help solve problems in industrial processes and promote further academic investigation. Given its scope, it offers a valuable resource for researchers and graduate students in the fields of bioengineering, food science, biochemistry, etc.

Nutrition, Life, Disease and Death -- Flax Bio-village Concept -- Status Paper on Linseed/Flax Agriculture -- Omega-3 Milk -- Omega-3 Egg -- Omega-3 Polyunsaturated Fatty Acids and Hyperlipidemias -- World Market of Omega-3 Fatty Acids -- Fortification of Food with Omega-3 Fatty Acids -- Importance of Polyunsaturated Acids from Marin Algae -- Emulsions of Omega-3 Fatty Acids for Better Bioavailability and Beneficial Health Effects -- Omega-3 Fatty Acids in Inflammatory Diseases -- Omega-3 Fatty Acids in Cancer: Insights into the Mechanism of Actions in Pre-clinical Cancer Models -- Linseed as a Functional Food for the Management of Obesity -- Role of Omega-3 Fatty Acids in Metabolic Syndrome -- Balancing Omega-6: Omega-3 Ratios in Oilseeds -- Omega-3 Fatty Acids and Diabetic Complications -- Omega-3 Fatty Acids and Mitochondrial Functions -- Omega-3 Fatty Acids and Alzheimer's Disease -- Prevention of Oxidative Stress by Omega-3 Fatty Acids in the Brain -- Role of Omega-3 Fatty Acids for Eye Health -- DHA-Rich Algae Oil is a Safe and Effective Vegetarian Source of Omega-3 -- Role of N-3 (Omega-3) Polyunsaturated Fatty Acids in Postpartum Depression: Mechanisms and Implications for Prevention and Treatment -- Influence of Omega-3 Fatty Acids on Bone Turnover -- Interactions between Omega-3 Fatty Acids and Iron -- Role of Omega-3 Fatty Acis in Major Cardiovascular Events-A Current View -- Modulation of Immune Response by Omega-3 in Health and Disease -- The Linoleic to Linolenic Intake Ration: The Fundamental Implications of Imbalance and Excess Looked at from both a Functional and Evolutionary Perspective-An Overview -- Bioactive Oxidised Products of Omega-6 and -3, Excess Oxidative Stress, Oxidised Dietary Intake, and Antioxidant Nutrient Deficiencies, in the Context of a Modern Diet -- In a Western dietary context excess oxidised linoleic acid (LA) of dietary and endogenous origin by; over-activation of PPAR-gamma so immune and inflammatory pathways, and cardiolipin damage, increases cardiovascular risk -- Linoleic and alpha-linolenic acid have central roles in brain energy substrate provision, endogenous lipid production, immune and repair function, via peroxisomal beta-oxidation related pathways? -- The roles of Linoleic and Alpha Linolenic Acid, their oxylipins, PPAR alpha delta and gamma related peroxisomal pathways, on obesity in the context of a 'Western' diet -- The crucial relevance of ALA and LA as primary peroxisomal beta-oxidation substrates, of oxidised LA as the primary endogenous activator of PPAR gamma, and energy deficit as the primary activator of PPAR alpha -- Effects of Omega-3 Fatty Acids in Myocardial Infarction -- Alternative Origins for Omega-3 Fatty Acids in the Diet -- Maternal Long Chain Polyunsaturated Fatty Acids and Pregnancy Outcome -- Role of Antioxidants in Human Health -- Role of Omega-3 Fatty Acids in Cardiovascular Disorders -- Beneficial Effect of Long-Chain Omega-3 Fatty Acids in Psoriasis -- Pharmacokinetics, Safety Profile of Omega-3 Polyunsaturated Fatty Acids -- Fish Oil Fatty Acids for Aging Disorders.

Over the last several years developing human research suggests that a component of omega-3 fatty acids, long chain ones, contribute particularly to health benefits. Omega-6/3 Fatty Acids: Functions, Sustainability Strategies and Perspectives focuses on developing information on this newly recognized key component. This volume uniquely, and for the first time, focuses on sustainability of natural sources of omega-3 fatty acids variants including long chain ones, and on ways to increase their use and availability to reduce major diseases. The authors review cardiovascular disease, neurological changes and mental health and other diseases like diabetes where long chain omega-3 fatty acids play protective roles from recent human trials. Each chapter evaluates developing information on the possible mechanistic role of long chain omega-3 fatty acids. After showing their requirement and involvement in health promotion there are reviews of various sources and ways to protect and promote them. Authors provide support for the benefits and sources of long chain omega-3 fatty acids and their increased dietary intake that reduce various physical and mental illnesses. Omega-6/3 Fatty Acids: Functions, Sustainability and Perspectives is a unique and important new volume that provides the latest data and reviews to physicians who need to assess serum omega-6/3 and fatty acids to help diagnose risks and change diets and to inform industry and the scientific community with reviews of research for actions including new studies and therapies.

This book is a concerted effort to put together the rapidly growing facets of biological data. It provides a platform for the readers to think about integrative approaches to solve complex biological problems. This fundamental book deals with the simplest concepts of omics to recent advancements in the field. The content is divided into seven chapters that provide insight into various omics approaches, omics technologies, and its applications. Each chapter delves into different molecular scales: genomics, transcriptomics, proteomics, and metabolomics. Further to provide a holistic view a chapter detailing microbiome has been included in the book. The sub-sections in the chapters is dedicated to introducing the various analytical tools such as next generation sequencing, chromatin immunoprecipitation, mass spectrometry, peptide mass fingerprinting, RNA Seq and NMR spectroscopy. It entails a chapter focused on the bioinformatics resources for analysis of the omics data. In summary, this comprehensive book emphasizes the recent advancements in the study of biomolecules spanning from DNA to metabolites.

Breast cancer is the most common cancer in females that accounts for highest cancer specific deaths worldwide. In the last few decades research has proven that breast cancer can be treated if diagnosed at early stages and proper therapeutic strategy is adopted. Omics-based recent approaches have unveiled the molecular mechanism behind the breast tumorigenesis and aid in identification of next-generation molecular markers for early diagnosis, prognosis, and even the effective targeted therapy. Significant development has taken place in the field of omics in breast cancer in the last decade. The most promising omics approaches and their outcomes in breast cancer have been presented in this book for the first time. The book covers omics technologies and budding fields such as breast cancer miRNA, lipidomics, epigenomics, proteomics, nutrigenomics, stem cell, pharmacogenomics and personalized medicine, and many more along with conventional topics such as breast cancer management etc. It is a research-based reference book useful for clinician-scientists, researchers, geneticists and health care industries involved in various aspects of breast cancer. The book will also be useful for students of biomedicine, pathology, and pharmacy.

This book is a collection of principles and current practices in omics research, applied to skeletal muscle physiology and disorders. The various sections are categorized according to the level of biological organization, namely, genomics (DNA), transcriptomics (RNA), proteomics (protein), and metabolomics (metabolite). With skeletal muscle as the unifying theme, and featuring contributions from leading experts in this traditional field of research, it highlights the importance of skeletal muscle tissue in human development, health and successful ageing. It also discusses other fascinating topics like developmental biology, muscular dystrophies, exercise, insulin resistance and atrophy due to disuse, ageing or other muscle diseases, conveying the vast opportunities for generating new hypotheses as well as testing existing hypotheses by combining high-throughput techniques with proper experiment designs, bioinformatics and statistical analyses. Presenting the latest research techniques, this book is a valuable resource for the physiology community, particularly researchers and grad students who want to explore the new opportunities for omics technologies in basic physiology research.

Omics for Personalized Medicine will give to its prospective readers the insight of both the current developments and the future potential of personalized medicine. The book brings into light how the pharmacogenomics and omics technologies are bringing a revolution in transforming the medicine and the health care sector for the better. Students of biomedical research and medicine along with medical professionals will benefit tremendously from the book by gaining from the diverse fields of knowledge of new age personalized medicine presented in the highly detailed chapters of the book. The book chapters are divided into two sections for convenient reading with the first section covering the general aspects of pharmaocogenomic technology that includes latest research and development in omics technologies. The first section also highlights the role of omics in modern clinical trials and even discusses the ethical consideration in pharmocogenomics. The second section is focusing on the development of personalized medicine in several areas of human health. The topics covered range from metabolic and neurological disorders to non-communicable as well as infectious diseases, and even explores the role of pharmacogenomics in cell therapy and transplantation technology. Thirty-four chapters of the book cover several aspects of pharmacogenomics and personalized medicine and have taken into consideration the varied interest of the readers from different fields of biomedical research and medicine. Advent of pharmacogenomics is the future of modern medicine, which has resulted from culmination of decades of research and now is showing the way forward. The book is an honest endeavour of researchers from all over the world to disseminate the latest knowledge and knowhow in personalized medicine to the community health researchers in particular and the educated public in general.

Omics Technologies and Bio-Engineering: Towards Improving Quality of Life, Volume 1 is a unique reference that brings together multiple perspectives on omics research, providing in-depth analysis and insights from an international team of authors. The book delivers pivotal information that will inform and improve medical and biological research by helping readers gain more direct access to analytic data, an increased understanding on data evaluation, and a comprehensive picture on how to use omics data in molecular biology, biotechnology and human health care.

Approach to the diagnosis and management of on-call problems -- Documentation of on-call problems -- Assessment and management of volume status -- Human immunodeficiency virus, hepatitis b virus, hepatitis c virus, meningococcus, influenza, ebola virus, and the house officer -- Abdominal pain -- Chest pain -- Combativeness : the out-of-control patient -- Confusion/decreased level of consciousness -- Decreased urine output -- Diarrhea -- Fall out of bed -- Fever -- Gastrointestinal bleeding -- Headache -- Heart rate and rhythm disorders -- High blood pressure -- Hypnotics, laxatives, analgesics, and antipyretics -- Hypotension and shock -- Leg pain -- Lines, tubes, and drains -- Polyuria, frequency, and incontinence -- Pronouncing death -- Seizures -- Shortness of breath -- Skin rashes and urticaria -- Stroke -- Syncope -- Transfusion reactions -- Acid-base disorder -- Anemia -- Calcium disorders -- Coagulation disorders -- Glucose disorders -- Potassium disorders -- Sodium disorders.