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  • Book
    Ayse Basak Engin, Atilla Engin, editors.
    Summary: "Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. "Obesity and Lipotoxicity" is a comprehensive review of the recent researches to provide a better understanding of the lipotoxicity-related mechanisms of obesity and the potential for the development of new treatment strategies. This book overviews the biochemical pathways leading to obesity-related metabolic disorders that occur subsequent to lipotoxicity. Chapters examine the deleterious effects of nutrient excess at molecular level including the cellular and molecular aspects of breast cancer, resistance to leptin, insulin, adiponectin, and interconnection between the circadian clock and metabolic pathways during high-fat feeding. "Lipotoxicity and Obesity" will be a useful resource for clinicians and basic science researchers, such as biochemists, toxicologists, immunologists, nutritionists, adult and pediatric endocrinologists, cardiologists, as well as students who are thought in this field"--Publisher's description.

    The definition and prevalence of obesity and metabolic syndrome / Atilla Engin
    Circadian rhythms in diet-induced obesity / Atilla Engin
    Eat and death: chronic over-eating / Atilla Engin
    Obesity, persistent organic pollutants and related health problems / Loukia Vassilopoulou, Christos Psycharakis, Demetrios Petrakis, John Tsiaoussis [and others]
    Human protein kinases and obesity / Atilla Engin
    Fat cell and fatty acid turnover in obesity / Atilla Engin
    Adipose tissue function and expandability as determinants of lipotoxicity and the metabolic syndrome / Stefania Carobbio, Vanessa Pellegrinelli, Antonio Vidal-Puig
    What is lipotoxicity? / Ayse Basak Engin
    The pathogenesis of obesity-associated adipose tissue inflammation / Atilla Engin
    Microbiota and lipotoxicity / Evren Doruk Engin
    Endoplasmic reticulum stress and obesity / Erkan Yilmaz
    Insulin resistance, obesity and lipotoxicity / Dilek Yazıcı, Havva Sezer
    Adipose tissue hypoxia in obesity and its impact on preadipocytes and macrophages: hypoxia hypothesis / Atilla Engin
    Adipocyte-macrophage cross-talk in obesity / Ayse Basak Engin
    Endothelial dysfunction in obesity / Atilla Engin
    Diet-induced obesity and the mechanism of leptin resistance / Atilla Engin
    Influence of antioxidants on leptin metabolism and its role in the pathogenesis of obesity / Harald Mangge, Christian Ciardi, Kathrin Becker, Barbara Strasser, Dietmar Fuchs [and others]
    Adiponectin-resistance in obesity / Atilla Engin
    Non-alcoholic fatty liver disease / Atilla Engin
    Lipotoxicity-related hematological disorders in obesity / Ibrahim Celalettin Haznedaroglu, Umit Yavuz Malkan
    MicroRNA and adipogenesis / Ayse Basak Engin
    The interactions between kynurenine, folate, methionine and pteridine pathways in obesity / Ayse Basak Engin, Atilla Engin
    Eligibility and success criteria for bariatric/metabolic surgery / Manuel F. Landecho, Víctor Valentí, Rafael Moncada, Gema Frühbeck
    Does bariatric surgery improve obesity associated comorbid conditions / Atilla Engin
    Obesity-associated breast cancer: analysis of risk factors / Atilla Engin
    Lipotoxicity in obesity: benefit of olive oil / Saad Elias, Sbeit Wisam, Arraf Luai, Barhoum Massad, Assy.
    Digital Access Springer 2017