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  • The summary of the published clinical guideline on Osteoarthritis. It links to the published guidance and key documents.
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  • The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis / Edward M. Schwarz ... [et al.] -- Activation of [gamma][delta] T cells by bisphosphonates / Keith Thompson ... [et al.] -- Identification of cell cycle-arrested quiescent osteoclast precursors in vivo / Naoyuki Takahashi ... [et al.] -- Megakaryocyte-bone cell interactions / Melissa A. Kacena and Wendy A. Ciovacco -- Regulation of osteoblast differentiation by Runx2 / Toshihisa Komori -- Communication between ephrinB2 and ephB4 within the osteoblast lineage / T.J. Martin ... [et al.] -- The unexpected link between osteoclasts and the immune system / Hiroshi Takayanagi -- NFATc1 in inflammatory and musculoskeletal conditions / Antonios O. Aliprantis and Laurie H. Glimcher -- Novel functions of RANK(L) signaling in the immune system / Andreas Leibbrandt and Josef M. Penninger -- Eph and ephrin interactions in bone / Koichi Matsuo -- How do bone cells secret proteins? / Haibo Zhao ... [et al.] -- Regulation of osteoclast apoptosis by Bcl-2 family protein Bim and caspase-3 / Sakae Tanaka ... [et al.] -- Regulation of bone formation and immune cell development by Schnurri proteins / Dallas C. Jones and Laurie H. Glimcher.
  • Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. It has become increasingly clear that critical interactions between these two organ systems frequently occur. This is particularly true for the development of immune cells in the bone marrow and for the function of bone cells in health and disease. However, because these two disciplines developed independently, investigators in each don't always fully appreciate the significance of the other. This book is meant to provide a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. Approximately half the book will focus on the role that osteoimmunology plays in the development of human diseases.
  • Osteonecrosis 2014
    Springer
    Part I. History -- 1. Osteonecrosis: Historical Perspective / Marvin E. Steinberg and David R. Steinberg -- Part II. Anatomy and Blood Flow -- 2. Vascular Anatomy and Blood Supply to the Femoral Head / Marcin Zlotorowicz and Jaroslaw Czubak -- 3. Ischemia and Reperfusion Injury in Bone / Howard Winet -- Part III. Epidemiology -- 4. The Prevalence of Osteonecrosis in Different Parts of the World / A.C. Gosling-Gardeniers, W.H.C. Rijnen, and J.W.M. Gardeniers -- 5. Epidemiology of Osteonecrosis in the USA / Sameer M. Naranje and Edward Y. Cheng -- 6. The Epidemiology of Osteonecrosis in Japan / Takuaki Yamamoto, Ryosuke Yamaguchi, and Yukihide Iwamoto -- 7. Epidemiology of Osteonecrosis of the Femoral Head in South Korea / Joon Soon Kang and Kee Hyung Rhyu --8. Current Trends of Osteonecrosis of the Femoral Head in Taiwan and China / Fang-Tsai Lee, Tso-Chiang Ma, and Mel S. Lee -- Part IV. Etiology -- 9. Genetic Studies in Osteonecrosis of the Femoral Head / Shin-Yoon Kim and Tae-Ho Kim -- 10. Osteonecrosis and Intravascular Coagulation Revisited / Lynne C. Jones and Deborah McK. Ciombor -- 11. Glucocorticoids (as an Etiologic Factor) / Eun Young Lee and Yun Jong Lee -- 12. Corticosteroid Usage and Osteonecrosis of the Hip / Jeffrey J. Cherian, Bhaveen H. Kapadia, Samik Banerjee, Julio J. Jauregui, and Michael A. Mont -- 13. Alcohol / Wakaba Fukushima and Yoshio Hirota -- 14. Traumatic Avascular Necrosis of the Femoral Head / Simon Damian Steppacher, Pascal Cyrill Haefeli, Helen Anwander, Klaus Arno Siebenrock, and Moritz Tannast -- 15. Posttraumatic Osteonecrosis of the Femoral Head / Taek Rim Yoon and Ha Sung Kim -- 16. Osteonecrosis in Sickle-Cell Disease / Philippe Hernigou and Gildasio Daltro -- 17. Autoimmune Disease (SLE, Antiphospholipid Syndrome), Posttransplantation (Kidney, Liver, Heart, Bone Marrow), and Other Risk Factors (Chemotherapy, Caisson Disease, Radiation, Pancreatitis, Gaucher's Disease) / Jeong Joon Yoo -- Part V. Pathology -- 18. Pathophysiology of Ischemic Diseases of the Hip: Osteonecrosis, Borderline Necrosis, and Bone Marrow Edema Syndrome / Kyung-Hoi Koo, Young-Kyun Lee, and Yun Jong Lee -- 19. The Pathology of Osteonecrosis of the Femoral Head / Takuaki Yamamoto -- Part VI. Clinical Manifestation -- 20. Natural History of Osteonecrosis / Samik Banerjee, Bhaveen H. Kapadia, Julio J. Jauregui, Jeffrey J. Cherian, and Michael A. Mont -- 21. Causes of Pain in Early and Advanced Stage Osteonecrosis / Vivek S. Jagadale and Edward Y. Cheng -- 22. Accumulation of Necrotic Fatty Marrow in Osteonecrotic Hips Mimicking Septic Arthritis / Tae-Young Kim, Kyung-Hoi Koo, and Javad Parvizi -- Part VII. Imaging Diagnosis -- 23. Radiography, MRI, CT, Bone Scan, and PET-CT / Kyung Nam Ryu, Wook Jin, and Ji Seon Park -- Part VIII. Staging and Classification -- 24. Ficat Staging System / Kyung-Hoi Koo -- 25. The University of Pennsylvania Classification of Osteonecrosis / David R. Steinberg and Marvin E. Steinberg -- 26. Natural Course and the JIC Classification of Osteonecrosis of the Femoral Head / Nobuhiko Sugano and Kenji Ohzono -- 27. Modified Kerboul Classification System of Necrotic Extent Using MRI / Yong-Chan Ha, Young-Kyun Lee, and Kyung-Hoi Koo -- 28. The ARCO Staging System: Generation and Evolution Since 1991 / J.W.M. Gardeniers, A.C. Gosling-Gardeniers, and W.H.C. Rijnen -- Part IX. Differential Diagnosis -- 29. Subchondral Stress Fracture of the Femoral Head / Hee Joong Kim, Jeong Joon Yoo, and Pil Whan Yoon -- 30. Bone Marrow Edema Syndrome of the Hip / Young-Kyun Lee and Kyung-Hoi Koo -- 31. Distinguishing Bone Marrow Edema Syndrome from Osteonecrosis / Marc W. Hungerford and Kyung-Hoi Koo -- Part X. Non-surgical Treatments -- 32. Treatment of Osteonecrosis of the Hip and Knee with Enoxaparin / Charles J. Glueck, Richard A. Freiberg, and Ping Wang -- 33. The Role of Coagulopathy in the Pathogenesis and Prevention of Corticosteroid-Induced Osteonecrosis / Takuaki Yamamoto, Goro Motomura, Ryosuke Yamaguchi, and Yukihide Iwamoto -- 34. Lipid-Lowering Agents and Their Effects on Osteonecrosis: Pros and Cons / Abdurrahman Kandil and Quanjun Cui -- 35. Is There a Role for BMPs in the Treatment of Osteonecrosis? / Philipp Leucht and Stuart B. Goodman -- 36. Alendronate in the Prevention of Collapse of the Femoral Head in Nontraumatic Osteonecrosis / Chung-Hwan Chen and Gwo-Jaw Wang -- 37. New Therapies of Bone Necrosis / Wolf Drescher, Matthias Knobe, Wolfgang Wagner, and Thomas Pufe -- Part XI. Surgical Treatments -- 38. Principles of Core Decompression for Osteonecrosis of the Hip / Bhaveen H. Kapadia, Samik Banerjee, Jeffrey J. Cherian, Julio J. Jauregui and Michael A. Mont -- 39. Stem Cells in Osteonecrosis: Cons / Anjan P. Kaushik, Anusuya Das, and Quanjun Cui -- 40. Cement Techniques in Hip Osteonecrosis with Collapse: From Traditional Methyl Methacrylate to Bone Substitutes and Stem Cells / Philippe Hernigou and Gildasio Daltro -- 41. Impaction Bone Grafting / Seung-Hoon Baek and Shin-Yoon Kim -- 42. Principles of Bone Grafting for Osteonecrosis of the Hip / Julio J. Jauregui, Samik Banerjee, Bhaveen H. Kapadia, Jeffrey J. Cherian, Kimona Issa, and Michael A. Mont -- 43. Vascularized Pedicle Iliac Bone Grafting for Osteonecrosis of the Femoral Head / Mel S. Lee -- 44. The Vascularized Fibular Graft in the Treatment of Osteonecrosis: Data, Dogma, and Controversies / Will Eward -- 45. Transtrochanteric Rotational Osteotomy for Femoral Head Osteonecrosis / Yong-Chan Ha, Jae-Hwi Nho, and Kyung-Hoi Koo -- 46. Posterior Rotational Osteotomy for Severe Femoral Head Osteonecrosis / Takashi Atsumi -- 47. Transtrochanteric Curved Varus Osteotomy for the Treatment of Osteonecrosis of the Femoral Head / Takuaki Yamamoto, Satoshi Ikemura, and Yukihide Iwamoto -- 48. Total Hip Arthroplasty Using Ceramic-on- Ceramic Articulation / Young-Kyun Lee, Ki-Choul Kim, Bun Jung Kang, and Kyung-Hoi Koo -- 49. Highly Crosslinked -Polyethylene Liners in Patients with Osteonecrosis of the Femoral Head in the United States and Europe / Patrick O'Toole and Javad Parvizi -- 50. Alumina Ceramic-on-Highly Cross- Linked Polyethylene Bearing in Cementless Total Hip Arthroplasty in Young Patients with Osteonecrosis of Femoral Head / Young-Hoo Kim -- 51. Hip Arthroplasty for Osteonecrosis of the Femoral Head / Harlan C. Amstutz, Michel J. Le Duff, and Mariam Al-Hamad -- 52. Resurfacing Arthroplasty for Osteonecrosis of the Femoral Head / Bernard N. Stulberg and Jayson D. Zadzilka -- Part XII. Osteonecrosis in Bones Other than the Hip -- 53. Multifocal Osteonecrosis / Samik Banerjee, Bhaveen H. Kapadia, Jeffrey J. Cherian, Julio J. Jauregui, and Michael A. Mont -- 54. Osteonecrosis of the Humeral Head / Nobuhiko Sugano -- 55. Knee Osteonecrosis / Karthik E. Ponnusamy, Savyasachi Thakkar, and Harpal S. Khanuja -- 56. Osteonecrosis of the Talus / Kyoung Min Lee, Sung Hun Won, and Moon Seok Park -- 57. Kienböck's Disease of the Lunate / Dawn M. LaPorte and Thomas J. Kim -- Part XIII. Legg-Calvé-Perthes Disease -- 58. The Epidemiology and Etiology of Perthes' Disease / Daniel C. Perry -- 59. Legg-Calvé-Perthes Disease: Pathology, Pathophysiology, and Pathogenesis of Deformity / Harry K.W. Kim -- 60. Legg-Calvé-Perthes Disease: Diagnosis, Imaging, and Classifications / Benjamin Shore and Harry K.W. Kim -- 61. Legg-Calvé-Perthes Disease: Treatments / Benjamin D. Martin and Harry K.W. Kim -- 62. Developing Medical Therapy for Legg-Calvé-Perthes' Disease / Harry K.W. Kim and David G. Little -- 63. Corticosteroid-Associated Osteonecrosis in Children / Scott Rosenfeld and Harry K.W. Kim -- Part XIV. Animal Models -- 64. Animal Models of Corticosteroid- Associated Bone Diseases / Lynne C. Jones, Michelle A. Tucci, Azeb Haile, and Dongqing Wang -- 65. Animal Models of Bone Necrosis: An Overview / Wagner Drescher, Matthias Knobe, Wolfgang Wagner, and Thomas Pufe.
  • Osteoporosis 2008
    Springer Protocols
  • Diagnosis -- Pathogenesis -- Assessment of fracture risk -- Bone densitometry: using dual-energy x-ray absorptiometry for monitoring -- Biochemical evaluation -- Secondary causes of osteoporosis -- Acquired vitamin D deficiency -- Treatment options -- Tailoring therapy to individual patients -- Determining success of therapy and what to do when therapy fails -- Future therapeutic options -- Case studies.
  • Osteoporosis is a serious problem worldwide, and its significance is continuing to increase as the world population grows and ages. Osteoporosis and Bone Densitometry Measurements provides a comprehensive review of the latest research on this potentially devastating condition. The book encompasses prevention, diagnosis, and therapy, providing state of the art information on each aspect. A wide range of topics are discussed, including differentiation between acute and chronic, benign and malignant vertebral fractures; the value of the WHO FRAX tool in patient evaluation; the roles of dual-energy X-ray absorptiometry, quantitative computed tomography, quantitative ultrasound, and high-resolution imaging; and the use of kyphoplasty and vertebroplasty to treat vertebral compression fractures. All chapters are written by acknowledged experts in the field.
  • The summary of the published clinical guideline on Osteoporosis fragility fracture. It links to the published guidance and key documents.
  • 2010 ClinicalKey
    Section 1. Essentials of bone biology -- The biochemistry of bone : composition and organization / Adele L. Boskey -- Bone remodeling : cellular activities in bone / David W. Dempster, Hua Zhou, Shi Shou Lu -- Assessment of bone turnover in men using biochemical markers / Patrick Garnero, Pawel Szulc -- Fundamentals of mineral homeostasis / David A. Hanley, K. Shawn Davison -- The mechanical properties of bone / David P. Fyhrie -- Essentials of bone biology : assessment of bone architecture / Thomas F. Lang -- Section 2. Development and growth of the male skeleton -- Skeletal growth in males / Qingju Wang, Ego Seeman -- Pubertal growth of the male skeleton / Vincent Gilsanz, Stefano Mora -- The effects of sex steroids on bone growth / Giampiero I. Baroncelli, Silvano Bertelloni -- Nutritional basis of skeletal growth / Connie M. Weaver, Elizabeth Haney -- Physical activity and skeletal growth / Heather M. Macdonald, Heather A. McKay, Melonie Burrows -- Section 3. Skeletal genetics -- The genetics of peak bone mass / Luigi Gennari, Robert F. Klein, Serge Ferrari -- Section 4. Aging and the male skeleton -- Age-related changes in bone remodeling and microarchitecture / Roger Zebaze, Ego Seeman -- Markers of bone remodeling and the aging skeleton / Serge Cremers, Christian Meier, Markus J. Seibel -- Alterations in mineral metabolism in the aging male / Shonni J. Silverberg, Bismruta Misra -- Changes in bone size and geometry with aging / Pawel Szulc -- Aging and bone loss / Steven Boonen ... [et al.] -- The effect of age on material properties / Charles H. Turner, Matthew R. Allen, David B. -- Section 5. Nutritional issues -- Calcium, bone strength and fractures / Laura A.G. Armas, Robert P. Heaney, Joan M. Lappe -- Vitamin D and bone / Roger Bouillon ... [et al.] -- Role of dietary protein in bone growth and bone loss / Rene Rizzoli -- Section 6. Sex steroids and the skeleton in men -- Section 7. Fractures in men -- Section 8. Metabolic bone disease in men -- Section 9. Diagnostic approach -- Section 10. Therapy.
  • How to Select Your Animal Model for Osteoporosis Research / A. Simon Turner -- Skeletal Phenotyping in Rodents: Tissue Isolation and Manipulation / Janet E. Henderson, Chan Gao and Edward J. Harvey -- Methods in Bone Biology in Animals: Biomechanics / José B. Volpon and Antonio C. Shimano -- Methods in Bone Histomorphometry for Animal Models / Natalie Dion, Audray Fortin and Louis-Georges Ste-Marie -- Methods in Bone Biology in Animals: Imaging / Blaine A. Christiansen and Mary L. Bouxsein -- Methods in Bone Biology in Animals: Biochemical Markers / Markus Herrmann -- Methods in Bone Biology: Cancer and Bone / Yu Zheng, Markus J. Seibel and Hong Zhou -- How to Test Osteoporosis Treatments in Experimental Animals / Robert J. van ʻt Hof -- The Ovariectomized Mice and Rats / Jameela Banu -- Classical Models of Senile Osteoporosis / Ken Watanabe -- Animal Models of Premature Aging / Wei Li and Gustavo Duque -- Nonhuman Primate Models of Osteoporosis / Susan Y. Smith, Aurore Varela and Jacquelin Jolette -- Other Large Animal Models / Susan Reinwald and David B. Burr -- Mouse models for the Study of Fracture Healing and Bone Regeneration / Joerg H. Holstein, Patric Garcia, Tina Histing, Moritz Klein and Steven C. Becker, et al.
  • Osteoporosis. 4th edition. v.1-2, 2013
    ScienceDirect
    2013 ClinicalKey
    Volume 1. I. Introduction: The bone organ system : form and function / Elise F. Morgan, George L. Barnes, Thomas A. Einhorn ; The nature of osteoporosis / Robert Marcus, David W. Dempster, Mary L. Bouxsein ; Reflections on osteoporosis / B.E. Christopher Nordin ; Reflections on development of concepts of intercellular communication in bone / T. John Martin ; Osteo-odyssey : a memoir / Paula H. Stern -- II. Cellular, molecular, and develomental biology of bone: Development of the skeleton / Sylvain Provot [and 3 others] ; The skeletal stem cell / Dongsu Park [and 3 others] ; Osteoclast biology / Timothy R. Arnett ; Osteoblast biology / Johannes P.T.M. van Leeuwen [and 4 others] ; Osteocyte biology / Lynda F. Bonewald ; The regulatory role of matrix protein in mineralization of bone / Adele L. Boskey, Pamela Gehron Robey -- III. Skeletal hormones and regulatory factors: Parathyroid hormone and parathyroid hormone-related protein / Robert A. Nissenson ; Vitamin D : biology, actions, and clinical implications / David Feldman, Aruna V. Krishnan, Srilatha Swami ; Regulation of bone cell function by estrogens / Suzanne E. Wardell, Donald P. McDonnell, Erik R. Nelson ; Androgens and skeletal biology : basic mechanisms / Kristine M. Wiren ; Phosphatonins / Peter J. Tebben, Theresa J. Berndt, Rajiv Kumar ; Skeletal growth factors / Ernesto Canalis ; Wnt signaling in skeletal homeostasis and diseases / Francesca Gori, Roland Baron -- IV. Skeletal structure and biomechanics: The mechanical behavior of bone / Lamya Karim [and 3 others] ; Cellular and molecular mechanotransduction in bone / Julia C. Chen, Alesha B. Castillo, Christopher R. Jacobs ; Adaptation of skeletal structure to mechanical loading / Marjolein C.H. van der Meulen, Christopher J. Hernandez ; Biomechanics of hip and vertebral fractures / Denise E. Anderson, Alexander G. Bruno, Mary L. Bouxsein ; Prevention of osteoporosis by physical signals : defining a potential role for nondrug strategies in the treatment of musculoskeletal injury and disease / Clinton T. Rubin [and and 3 others] -- V. Epidemiology of osteoporosis: Epidemiologic methods in studies of osteoporosis / Kristine E. Ensrud, Brent C. Taylor ; Genetic determinants of osteoporosis / André G. Uitterlinden, M. Carola Zillikens, Fernando Rivadeneira ; Race, ethnicity, and osteoporosis / Jane A. Cauley, Dorothy A. Nelson ; Geographic variability in hip and vertebral fractures / Ghada Ballane [and 3 others] ; Nutrition and risk for osteoporosis / Robert P. Heaney ; Physical activity and exercise in the maintenance of the adult skeleton and the prevention of osteoporotic fractures / Dennis R. Taaffe [and 4 others] ; Premenopausal reproductive and hormonal characteristics and the risk for osteoporosis / John F. Randolph Jr., Maryfran R. Sowers ; Clinical and epidemiological studies : skeletal changes across menopause / Jane A. Cauley, Michelle E. Danielson, Gail A. Greendale ; Osteoporosis in men: epidemiology, pathophysiology, and clinical characterization / Eric S. Orwoll, Dirk Vanderschueren, Steven Boonen ; Falls as risk factors for fracture / Sarah D. Berry, Douglas P. Kiel ; Nonskeletal risk factors for osteoporosis and fractures / Jeri W. Nieves ; Outcomes following osteoporotic fractures / Jacqueline R. Center -- VI. General pathophysiology of osteoporosis: Skeletal heterogeneity and the purposes of bone remodeling : implications for the understanding of osteoporosis /A. Michael Parfitt ; On the evolution and contemporary roles of bone remodeling / Paul Kostenuik ; Cytokines and the pathogenesis of osteoporosis / Joseph Lorenzo ; Animal models for osteoporosis / Urszula T. Iwaniec, Russell T. Turner ; Bone and fat / Francisco J.A. de Paula [and 3 others] ; Bone mineral acquisition in utero and during infancy and childhood / Linda A. DiMeglio, Mary B. Leonard ; Bone acquisition in adolescence / Heather M. MacDonald, Christa L. Hoy, Heather A. McKay -- Volume 2. Osteoporosis in childhood and adolescence / Leanne Ward, M. Zulf Mughal, Laura K. Bachrach ; Osteoporosis associated with pregnancy / Rachel B. Wagman, Robert Marcus ; Osteoporosis in premenopausal women / Adi Cohen ; Estrogen deficiency, postmenopausal osteoporosis, and age-related bone loss / Sundeep Khosla, Roberto Pacifici --VII. Spectrum of secondary osteoporosis: Immobilization osteoporosis / William A. Bauman, Christopher P. Cardozo ; Osteoporosis associated with illnesses and medications / Elizabeth Shane, Robert Marcus ; Glucocorticoid-induced osteoporosis / Robert A. Adler, Robert S. Weinstein, Kenneth G. Saag ; Anticonvulsant-related bone disease / Alison M. Pack ; Thyroid hormone and the skeleton / Daniel Baran ; The skeletal actions of parathyroid hormone in primary hyperparathyroidism and in osteoporosis / John P. Bilezikian, Lorraine A. Fitzpatrick, Shonni J. Silverberg ; Osteogenesis imperfecta and other defects of bone development as occasional causes of adult osteoporosis / Jay R. Shapiro ; HIV and osteoporosis / Todd T. Brown, Michael T. Yin ; Obesity, diabetes, and fractures / Melissa Premaor, Juliet Compston ; Osteoporosis in organ transplant patients / Emily Stein, Elizabeth Shane ; Osteoporosis associated with rheumatologic disorders / Steven R. Goldring ; Osteoporosis associated with chronic kidney disease / Susan M. Ott, Grahame Elder ; Oral bone loss and systemic osteoporosis : weighing the risk benefit ratio of treatment / Marjorie K. Jeffcoat -- VIII. Cancer and osteoporosis: Cancer treatment-induced bone loss in patients with breast cancer : pathophysiology and clinical perspectives / Allan Lipton, Roger Dansey, Robert Coleman ; Pathophysiology-prostate cancer / Philip J. Saylor, matthew R. Smith ; Mechanisms of bone destruction in myeloma / Rebecca Silbermann, G. David Roodman --IX. Diagnosis and evaluation: Evaluation of the patient at risk for osteoporosis / E. Michael Lewiecki ; Imaging of osteoporosis / James F. Griffith, Harry K. Genant ; Osteoporosis : who should be treated? Who should be screened? / Cynthia A. Stuenkel, Bruce Ettinger ; Clinical use of bone densitometry / Sydney Lou Bonnick, Paul Miller ; Biochemical markers of bone turnover in osteoporosis / Pawel Szulc, Douglas C. Bauer ; Fracture risk assessment : the development and application of FRAX® / John A. Kanis [and 3 others] -- X. Patient management: Orthopedic aspects of osteoporosis / Susan V. Bukata ; Falls prevention interventions / Kim Delbaere, Catherine Sherrington, Stephen R. Lord ; Physical therapy, physical modalities, and exercise regimens in the management of osteoporosis / Susan B. Broy, Karen L. Kemmis ; Calcium in the treatment of osteoporosis / Robert P. Heaney ; Vitamin D and its metabolites and analogs in the management of osteoporosis / Roger Bouillon, Ian R. Reid ; Alternative therapy through nutrients and nutraceuticals / Jeri W. Nieves -- XI. Pharmacotherapeutics: Design considerations for clinical investigations of osteoporosis / Robert P. Heaney ; Lessons from bone histomorphometry on the mechanisms of action of osteoporosis drugs / Hua Zhou, David W. Dempster ; -- Estrogen and estrogen analogs for prevention and treatment of osteoporosis / Margery L.S. Gass, Sobia Khan ; Androgens / Mona Al Mukaddam, Peter J. Snyder ; Calcitonin in osteoporosis / Roberto Civitelli ; Bisphosphonates : pharmacology and use in the treatment of osteoporosis / Dima L. Diab, Nelson B. Watts, Paul D. Miller ; Osteonecrosis of the jaw and atypical femoral fractures / Elizabeth Shane, Sundeep Khosla, David Burr ; Condition critical : compliance and persistence with osteoporosis medications / Deborah T. Gold ; Denosumab for the treatment of osteoporosis / Michael R. McClung ; Strontium ranelate in the prevention of osteoporotic fractures / René Rizzoli ; Parathyroid hormone treatment for osteoporosis / Felicia Cosman, Robert Lindsay ; New approaches to osteoporosis therapeutics /Aline Costa [and 3 others] ; The past, present, and uncertain future of therapeutic innovation in osteoporosis /Hunter Heath III.
  • Ch. 1. The necessity of a managed care approach for osteoporosis -- Ch. 2. Effects of aging on bone structure and metabolism -- Ch. 3. The genetics of osteoporosis -- Ch. 4. Bone mass measurement techniques in clinical practice -- Ch. 5. Biochemical markers of bone turnover -- Ch. 6. Calcium, vitamin D, and bone metabolism -- Ch. 7. Estrogens and selective estrogen receptor modulators for prevention and treatment of osteoporosis -- Ch. 8. Bisphosphonate treatment for osteoporosis -- Ch. 9. Calcitonin treatment in postmenopausal osteoporosis -- Ch. 10. Therapy with vitamin D metabolites, sodium fluoride, thiazides, and isoflavones -- Ch. 11. Orthopedics and the osteoporotic syndrome -- Ch. 12. Glucocorticoid-related osteoporosis -- Ch. 13. Osteoporosis and the bone biopsy.
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    Definitions, terminology, and classification. -- Anatomy. -- Physiology, pathophysiology, and pathogenesis. -- Epidemiology. -- Microbiology. -- Immunology. -- Diagnosis. -- Management. -- Complications and sequelae: intratemporal. -- Complications and sequelae: intracranial.
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  • Otologic Surgery--the third edition of this invaluable surgical reference--has been thoroughly updated to reflect the latest advances in the field and covers all aspects of surgery of the ear and skull base. Derald E. Brackmann, MD, Clough Shelton, MD, and Moises A. Arriaga, MD bring you seven new chapters on the hot topics of Cartilage Tympanoplasty, Reversible Canal Wall Down Mastiodectomy, Superior Semicircular Canal Dehiscence Syndrome, Endoscopic Skull Base Surgery, Far Lateral Transcondylar Approach, Stereotactic Radiation Therapy, and Vascular Considerations in Neurotology. These extensive updates, along with the inclusion of new contributors and the elimination of redundant chapters, ensure that this book provides you with the essential information you need to choose and perform state-of-the-art surgical techniques. The companion web site at expertconsult.com features the fully searchable text, as well as a video library and question and answer section. Discusses controversies and alternate approaches so you can make a well-informed decision from the full range of choices. Presents the expertise and insights from more than 50 leading specialists to provide you with authoritative advice on surgical problems. Provides detailed visual guidance on how to perform procedures through step-by-step illustrations.
  • "Expanding developments in the field have prompted a welcome increase among interested students. Interventions that were once considered somewhat esoteric by some might now be considered part of the medical mainstream. Cochlear implantation is certainly an example of such an intervention. As a consequence of these developments, a need to convey the core fund of knowledge to a larger more diverse group of trainees has arisen. With this in mind, this book was created to provide the basic concepts of otology, neurotology, and lateral skull base surgery in a rather simple, illustrated format for the new student interested in the field. While not intended to replace the more comprehensive, authoritative works in the field, this manual is meant only to create a "jumping on" point for continued study"--Provided by publisher.
  • Neurogenetic origins of behavior -- Jinn in the genome -- 2B or not 2B? -- Stephen Mobley and his X-chromosome -- Dial multifactorial for murder : the intersection of genes and culture -- Distorted capacity I : the measure of the impaired will -- Distorted capacity II: neuropsychiatric diseases and the impaired will -- Inheritance of behavior and genes for behavior : gene wars -- Scientific and historic bases of genethics: who watches the geneticists and by what principles? -- World is double helical -- DNA, RNA, and proteins in a few easy pieces -- Stochastic brain : from DNA blueprint to behavior -- Reintroducing genes and behavior -- Warriors and worriers -- How many genes does it take to make a behavior? -- Genesis and genetics of sexual behavior -- Gene by environment interaction -- Epigenetic revolution : finding the imprint of the environment on the genome -- DNA on trial -- Parents and children : neurogenetic determinism and neurogenetic individuality -- Summing up genetic predictors of behavior.
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    The author uses his own experiences as a primary care physician to describe the state of his profession and argues that the health care system will collapse without a strong physician-patient relationship and that the role of the primary care physician must change to survive.
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    The predictive value of detailed histological staging of surgical resection specimens in oral cancer -- Survival after treatment of intraocular melanoma -- Recent developments in relative survival analysis -- Environmental and genetic risk factors of lung cancer -- Chaos, cancer, the cellular operating system and the prediction of survival in head and neck cancer -- Flexible hazard modelling for outcome prediction in cancer: perspectives for the use of bioinformatics knowledge -- Information geometry for survival analysis and feature selection by neural networks -- Artificial neural networks used in the survival analysis of breast cancer patients: a node-negative study -- The use of artificial neural networks for the diagnosis and estimation of prognosis in cancer patients -- Machine learning contribution to solve prognostic medical problems -- Classification of brain tumors by pattern recognition of magnetic resonance imaging and spectroscopic data -- Towards automatic risk analysis for hereditary non-polyposis colorectal cancer based on pedigree data -- The impact of microarray technology in brain cancer -- The web and the new generation of medical information systems -- Geoconda: a web environment for multi-centre research -- The development and execution of medical prediction models.
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  • Discovery of the Outer Membrane Vesicles: Revisiting Contemporary Works -- Gram-Negative Bacteria: The cell Membranes -- Factors Affecting Production of Outer Membrane Vesicles -- Outer Membrane Vesicles as Carriers of Biomaterials -- Outer Membrane Vesicles and the Biofilm Formation -- Outer Membrane Vesicles: Interaction with Prokaryotes and Eukaryotes -- Biogenesis of Outer Membrane Vesicles -- Release of Outer Membrane Vesicles: Is it a Novel Secretion Mechanism? --Outer Membrane Vesicles: Physiological Medical Applications -- Concluding Notes.
  • A brief overview of molecular genetics -- An overview of information theory -- More on molecular genetics -- More on information theory -- An outline of error-correcting codes -- DNA is an ephemeral memory -- A toy living world -- Subsidiary hypothesis, nested system -- Soft codes -- Biological reality conforms to the hypotheses -- Identification of genomic codes.
  • The Breast Clinic -- The Asymptomatic Woman -- Anatomy, Congenital Aberrations, and Physiological Changes -- Clinical Examination of the Breast -- Imaging in Breast Related Diseases -- Breast Tissue Diagnosis -- Breast Pain -- Inflammatory Diseases of the Breast -- Benign Lesions of the Breast -- Nipple Discharge -- Miscellaneous Minor Disorders of the Breast -- Staging and Work Up of the Non Invasive Breast Cancer -- Staging and Work Up of Invasive Breast Cancer -- Breast Cancer Special Issues -- Breast Cancer in General Population -- The Role of Surgery -- The Role of Adjuvant Radiation Therapy -- The role of Adjuvant Systemic Therapy -- Male Breast Diseases -- Loco-Regional Breast Cancer Recurrences -- Follow Up.
  • Ovarian cancer 2010
    ClinicalKey
    Practical, authoritative, and highly-illustrated, this volume in the brand new Early Detection and Treatment of Cancer series covers current protocols and the latest advances in diagnostic imaging and molecular and serologic markers for ovarian cancer. Apply expert advice on the best next-step plan for different presentations and tips for less invasive protocols. Get clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed for accurate diagnosis and staging. Clear figures, tables, and boxes illustrate step-by-step care of the full range of problems encountered.
  • "Today, we are exposed to an ever-growing number of chemicals in the environment and there is an increasing awareness of the effects of these chemicals on the ovaries. As such, the potential for xenobiotic-induced infertility needs to be better understood. Additionally, menopause-associated disorders are of growing health concern in view of the fact that by the year 2025, 19.5% of the population of the U.S. will be menopause-aged women. Exploring research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles, this book is an essential resource for researchers in academia, regulatory agencies, and industry"--Provided by publisher.
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  • Overactive Bladder in Clinical Practice provides a timely and comprehensive update on the overactive bladder (OAB) syndrome. The symptoms of urgency, with or without urge incontinence, usually with frequency or nocturia, now defined as the overactive bladder syndrome, have become a hot topic in urology, gynecology and urogynecology. Epidemiological data show very high disease prevalence (19%), particularly when compared with other chronic conditions such as diabetes (2%) and asthma (7%). OAB symptoms impact severely on patient's quality of life, causing significant impairment of patient vitality and limiting their physical role, similar to diabetes. The OAB syndrome involves all age groups, both sexes and is frequently found in neurogenic patients. This book will cover all aspects of OAB epidemiology, economics, pathophysiology, conservative, pharmaceutical and surgical and is invaluable reading for residents and trainees in urology, gynecology and urogynecology.
  • The second edition of this highly successful book updates the reader on progress and developments in the field of ovulation induction and controlled ovarian stimulation. Furthermore, it provides the busy clinician with a reliable overview of the principles involved and the management needed. As with the previous edition, the emphasis throughout this book is on logical evidence and evidence-based solutions, supplemented with Professor Roy Homburgs extensive clinical experience gleaned from more than forty years working in the field. A number of highly useful algorithms and explanatory tables reinforce this approach, ensuring that the reader is presented with easy-to-grasp, well-presented information that maximizes clarity and understanding. Ovulation Induction and Controlled Ovarian Stimulation: A Practical Guide offers a concise, no-nonsense, practical guide to ovulation induction and controlled ovarian stimulation and will be an essential resource for general gynaecologists, fertility specialists and trainees, health workers and students.
  • A complete text of the 2nd. ed. of the Oxford English dictionary with quarterly updates, including revisions not available in any other form.
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    Good surgical practice -- Principles of surgery -- Surgical pathology -- Practical procedures -- Head and neck surgery -- Breast and endocrine surgery -- Upper gastrointestinal surgery -- Liver, pancreatic, and biliary surgery -- Abdominal wall -- Urology -- Colorectal surgery -- Paediatric surgery -- Major trauma -- Orthopaedic surgery -- Plastic surgery -- Cardiothoracic surgery -- Peripheral vascular disease -- Transplantation -- Surgery in tropical diseases -- Eponymous terms and rarities.
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  • Includes all of words, phrases, and translations, in French, German, Spanish and Italian from the print dictionaries. Users can search the full A-Z from both sides of the dictionary in Oxford's unabridged bilingual dictionaries: French, German, Spanish, and Italian.
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    v. 1. Musculo-skeletal system -- v. 2. Thorax and abdomen -- v. 3. Head and neck.
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    v. 1. -- section 1. On being a patient -- section 2. Modern medicine: foundations, achievements, and limitations -- section 3. Global patterns of disease and medical practice -- section 4. Cell biology -- section 5. Immunological mechanisms -- section 6. Principles of clinical oncology -- section 7. Infection -- section 8. Sexually transmitted diseases and sexual health -- section 9. Chemical and physical injuries and environmental factors and disease -- section 10. Clinical pharmacology -- section 11. Nutrition -- section 12. Metabolic disorders -- v. 2. -- section 13. Endocrine disorders -- section 14. Medical disorders in pregnancy -- section 15. Gastroenterological disorders -- section 16. Cardiovascular disorders -- section 17. Critical care medicine -- section 18. Respiratory disorders -- section 19. Rheumatological disorders -- v. 3. -- section 20. Disorders of the skeleton -- section 21. Disorders of the kidney and urinary tract -- section 22. Disorders of the blood -- section 23. Disorders of the skin -- section 24. Neurological disorders -- section 25. The eye -- section 26. Psychiatry and drug related problems -- section 27. Forensic medicine -- section 28. Sports medicine -- section 29. Geratology -- section 30. Pain -- section 31. Palliative medicine -- section 32. Biochemistry in medicine -- section 33. Acute medicine.
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    Part I: Foundations -- A brief history of psychopathology / Theodore Millon -- Classification / Roger K. Blashfield, Jared W. Keeley, and Danny R. Burgess -- Developmental pathogenesis / Theodore Millon -- Studying psychopathology / Michael L. Raulin and Scott O. Lilienfeld -- Part II: Major Axis I syndromes -- Anxiety disorders: panic and phobias / Steven Taylor, Brian J. Cox, and Gordon J. G. Asmundson -- Generalized anxiety disorder and obsessive-compulsive disorder / Timothy A. Brown and Amy E. Lawrence -- Posttraumatic stress disorder / Richard J. McNally -- Mood disorders: biological bases / Sheri L. Johnson ... [et al.] -- Depression: social and cognitive aspects / Rick E. Ingram, Walter D. Scott, and Sarah Hamill -- Substance abuse: etiological considerations / Robert O. Pihl -- Substance abuse: diagnosis, comorbidity, and psychopathology / Susan R. Tate, Michelle L. Drapkin, and Sandra A. Brown -- Schizophrenia: etiology and neurocognition / Barbara A. Cornblatt ... [et al.] -- Schizophrenia: interpersonal functioning / Jill M. Hooley -- Paranoid and delusional disorders / Paul H. Blaney -- Part III: Other Axis I syndromes -- Sexual dysfunctions / Donald S. Strassberg and Michael A. Perelman -- Eating disorders / Howard Steiger and Kenneth R. Bruce -- Dissociative disorders / Onno van der Hart and Ellert R. S. Nijenhuis -- Somatoform disorders / Theo K. Bouman and Georg H. Eifert -- Sleep/wake disorders / Charles M. Morin and Jack D. Edinger -- Sexual disorders / James M. Cantor, Roy Blanchard, and Howard Barbaree -- Part IV: Axis II disorders -- Personality and its disorders: structural models, mathematical methods, and theoretical conceptions / Theodore Millon -- Schizoid and avoidant personality disorders / David P. Bernstein, Arnoud Arntz, and Laura Travaglini -- Dependent and histrionic personality disorders / Robert F. Bornstein and Iris L. Malka -- Psychopathy / Robert D. Hare and Craig S. Neumann -- Sadistic personality disorder / Michael H. Stone, Jeremy R. Butler, and Kathleen M. Young -- Obsessive-compulsive and negativistic personality disorders / Joseph T. McCann -- Schizotypic psychopathology: theory, evidence, and future directions / Mark F. Lenzenweger -- Borderline personality disorder / Joel Paris -- Depressive personality disorder / Daniel N. Klein and Melissa L. Bessaha -- Narcissistic personality disorder / Elsa Ronningstam.
  • Oxidants and antioxidants. Part A-B pt. A-B, 1999.
    ScienceDirect
    pt. B ScienceDirect
  • Oxidatively generated damage to cellular DNA : mechanistic aspects / Jean Cadet ... [et al.] -- Chlorination and nitration of DNA and nucleic acid components / Clare L. Hawkins ... [et al.] -- Prevention of the mutagenicity and cytotoxicity of oxidized purine nucleotides / Yusaku Nakabeppu ... [et al.] -- Nucleotide incision repair : an alternative and ubiquitous pathway to handle oxidative DNA damage / Sophie Couvé-Privat ... [et al.] -- OGG1 : from structural analysis to the knockout mouse / Arne Klungland, Jon K. Laerdahl, and Torbjörn Rognes -- Processing of 3'-end modified DNA strand breaks induced by oxidative damage / Jason L. Parsons, Emma Boswell, and Grigory L. Dianov -- Oxidative damage and promoter function / David Mitchell and Rita Ghosh -- Oxidative DNA damage and telomere shortening / Torsten Richter and Thomas von Zglinicki -- Oxidative damage and repair in the mitochondrial genome / Lene Juel Rasmussen and Keshav K. Singh -- The role of oxidative damage to nucleic acids in the pathogenesis of neurological disease / V. Prakash Reddy ... [et al.] -- Nucleic acid oxidation and the pathogenesis of cardiovascular diseases / Maria Grazia Andreassi -- Oxidative DNA damage and carcinogenesis / Ryszard Olinski, Marek Foksinski, and Barbara Tudek -- The physiological and pathological roles of oxidative damage to DNA in relation to life stage / Alberto Izzotti -- Analysis of 8-hydroxy-2'-deoxyguanosine as a marker of oxidatively damaged DNA in relation to carcinogenesis and aging / H. Kasai ... [et al.] -- Oxidatively damaged DNA and inflammation / Peter C. Dedon and Marita C. Barth -- The role of antioxidants in the prevention of oxidative damage to nucleic acids / Peter Muller and Steffen Loft.
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  • Cardiorespiratory function is prominently affected by oxidative stress. Cigarette smoking is the archetype of oxidative and nitrative stress and free radical formation. New adverse effects of smoking keep on ppopping up in research. The chapters provide the comprehensive view of new developments in this area regarding cardiovascular and lung function and muscle catabolism. Alterations in inflammatory cytokines and proteins as well as degradation of muscle proteins due to smoking, by far unrecognized, caused by oxidative stress also are presented. Much less is known about the effect of cognitive stress on vagally-mediated cardiorespiratory function and surprisingly, on vagal immune pathway. The experimental studies also show that clinically important meconium aspiration syndrome contains an oxidative trait which is amenable to antioxidative treatment. This volume creates a source of information on the damaging role of oxidative stress in cardiorespiratory function that has by far not been available.
  • Oxidative stress and disease v. 6-8, 10-22, 29-, 2001-02, 2004-06, 2012-
    CRCnetBase
  • Chapter 1: The Role of Free Radicals in the Nervous System -- Chapter 2: Why Is the Nervous System Vulnerable to Oxidative Stress? -- Chapter 3: Perinatal Hypoxic-Ischemic Neural Injury and Free Radical Injury: A Fine Balance -- Chapter 4: Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy -- Chapter 5: Oxidative Stress in Multiple Sclerosis Pathology and Therapeutic Potential of Nrf2 Activation -- Chapter 6: Free Radicals in Central Nervous System Inflammation.
  • Introduction: Oxidation and inflammation, a molecular link between non-communicable diseases -- Oxidative stress and DNA damage in obesity-related tumorigenesis -- High density lipoproteins and ischemia reperfusion injury: the therapeutic potential of HDL to modulate cell survival pathways -- The DING family of phosphate binding proteins in inflammatory diseases -- Inflammation, infection, cancer and all that...the role of paraoxonases -- Autophagy is an inflammation-related defensive mechanism against disease -- Delta-5 and delta-6 desaturases: crucial enzymes in polyunsaturated fatty acid-related pathways with pleiotropic influences in health and disease -- Systemic inflammation, intestine and paraoxonase-1 -- Serotonin modulation of macrophage polarization: inflammation and beyond -- Energy metabolism and metabolic sensors in stem cells: the metabostem crossroads of aging and cancer -- Molecular promiscuity of plant polyphenols in the management of age-related diseases: far beyond their antioxidant properties -- Postprandial inflammation: targeting glucose and lipids -- Dynamic interplay between metabolic syndrome and immunity -- The axis AGE-RAGE-soluble RAGE and oxidative stress in chronic kidney disease -- The chemokine (C-C motif) ligand 2 in neuroinflammation and neurodegeneration.
  • Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
  • This volume details how oxidative stress in cancer biology can be utilized to more effectively design interventions to enhance therapeutic responses while causing fewer treatment limiting complications.
  • Oxygen biology and hypoxia 2007
    ScienceDirect
  • Print Material
  • Air and fire : Carl Wilhelm Scheele, Torbern Bergman, the Royal Society of Sciences and the discovery of oxygen in Uppsala in 1772 / Lars-Olof Sundelöf -- Mathematical modeling of the interactiion betwen oxygen, nitric oxide and superoxide / Donald G. Buerk -- Haemoglobin saturation controls the red blood cell mediated hypoxic vasorelaxation / Andrew G. Pinder ... [et al.] -- Blood vessel specific vaso-activity to nitrite under normoxic and hypoxic conditions / Thomas E. Ingram ... [et al.] -- Nitrite-induced improved blood circulation associated with an increase in a pool of RBN-NO with NO bioactivity / Joseph M. Rifkind ... [et al.] -- The control of oxidative phosphorylation in the adrenal gland (Y1) cell line / James E.J. Murphy and Richard K. Porter -- Replication of murine mitochondrial DNA following irradiation / Hengshan Zhang ... [et al.] -- Effects of anesthesia on brain mitochondrial function, blood flow, ionic and electrical activity monitored in vivo / Nava Dekel ... [et al.] -- The influence of flow redistribution on working rat muscle oxygenation / Louis Hoofd and Hans Degens -- Heterogeneity of capillary spacing in the hypertrophied plantaris muscle from young-adult and old rats / Hans Degens, Christopher I. Morse, and Maria T.E. Hopman -- Microvascularity of the lumbar erector spinae muscle during sustained prone trunk extension test / Rammohan V. Maikala and Yagesh N. Bhambhani -- Fiber capillary supply related to fiber size and oxidative capacity in human and rat skeletal muscle / Rob C.I. Wüst, Sarah L. Gibbings, and Hans Degens -- Novel therapeutic approach targeting the HIF-HRE system in the kidney / Masaomi Nangaku -- Carotid body sensory discharge and glomus cell HIF-1[alpha] are regulated by a common oxygen sensor / S. Lahiri ... [et al.] -- Impact of reactive oxygen species on the expression of adhesion molecules in vivo / Oliver Thews ... [et al.] -- Mini sensing chip for point-of-care acute myocardial infarction diagnosis utilizing micro-electro-mechanical system and nano-technology / Jianting Wang ... [et al.] -- A chemical biosynthesis design for an antiatherosclerosis drug by acyclic tocopherol intermediate analogue based on "isoprenomics" / Yoshihiro Uto ... [et al.] -- Zymogen protein C concentrate for safer heterozygote surgery, "I am a guinea pig!" / Duane F. Bruley -- Steady state redox levels in cytochrome oxidase : relevance for in vivo near infrared spectroscopy (NIRS) / Chris E. Cooper ... [et al.] -- Bicuculline-induced seizures : a challenge for optical and biochemical modeling of the cytochrome oxidase CUa NIRS signal / Chris E. Cooper ... [et al.] -- A method to calculate arterial and venous saturation from near infrared spectroscopy (NIRS) / Jan Menssen ... [et al.] -- Development of a dynamic test phantom for optical topography / Peck H. Koh, Clare E. Elwell, and David T. Delpy -- Numerical simulation of oxygen transport in cerebral tissue / Toshihiro Kondo ... [et al.] -- Non-invasive estimation of metabolic flux and blood flow in working muscle : effect of blood-tissue distribution / Nicola Lai ... [et al.] -- Oxygen extraction index measured by near infrared spectroscopy : a parameter for monitoring tissue oxygenation? / Oskar Baenziger ... [et al.] -- Non-invasive measurement of the superficial cortical oxygen partial pressure / Chris Woertgen ... [et al.] -- One sensor fits all : a new approach in monitoring brain physiology / H. Doll ... [et al.] -- Evaluation of NIRS data based on theoretical analysis of oxygen transport to cerebral tissue / Kazunori Oyama ... [et al.] -- Myocardial capillary net and blood constituents in streptozotocin (STZ-)-induced diabetic rats / Tomiyasu Koyama and Akira Taka -- Effects of proinsulin C-peptide on oxygen transport uptake and utilization in insulinopenic diabetic subjects : a review / Lina Nordquist and Sara Stridh -- Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging / Jenny Edlund ... [et al.] -- Identification and distribution of uncoupling protein isoforms in the normal and diabetic rat kidney / Malou Friederich ... [et al.] -- Iodinated contrast media decrease renomedullary blood flow : a possible cause of contrast media-induced nephropathy / Per Liss ... [et al.] -- C-peptide normalizes glomerular filtration rate in hyperfiltrating conscious diabetic rats / Sara Stridh ... [et al.] -- Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents / Jerry D. Glickson ... [et al.] -- Prognostic potential of the pre-therapeutic tumor oxygenation status / Peter Vaupel -- Histological basis of MR/optical imaging of human melanoma mouse xenografts spanning a range of metastatic potentials / He N. Xu ... [et al.] -- The relationship between vascular oxygen distribution and tissue oxygenation / Alexandru Daşu and Iuliana Toma-Daşu -- Intraoperative measurement of colonic oxygenation during bowel resection / Daya B. Singh ... [et al.] -- Quantifying tumour hypoxia by PET imaging : a theoretical analysis / Iuliana Toma-Daşu, Alexandru Da̧su, and Anders Brahme -- New measurements for assessment of impaired cerebral autoregulation using near-infrared spectroscopy / Dominique De Smet ... [et al.] -- Single shot T₁p magnetic resonance imaging of metabolically generated water in vivo / Eric A. Mellon ... [et al.] -- Brain tissue oxygen consumption and supply induced by neural activation : determined under suppressed hemodynamic response conditions in the anesthetized rat cerebral cortex / Kazuto Masamoto ... [et al.] -- Brain oxygen balance under various experimental pathophysiological conditions / Michal Schechter, Judith Sonn, and Avraham Mayevsky -- Ketones suppress brain glucose consumption / Joseph C. LaManna ... [et al.] -- False positives in functional near-infrared topography / Ilias Tachtsidis ... [et al.] -- Relationship between brain tissue haemodynamics, oxygenation, and metabolism in the healthy human adult brain during hyperoxia and hypercapnea / Ilias Tachtsidis ... [et al.] -- Use of a Codman microsensor intracranial pressure probe : effects on near infrared spectroscopy measurements and cerebral hemodynamics in rats / Helga Blockx, Willem Flameng, and Geofrey De Visscher -- Effect of severe hypoxia on prefrontal cortex and muscle oxygenation responses at rest and during exhaustive exercise / Thomas Rupp and Stéphane Perrey.
  • Part 1. Physiology and pathophysiology of O2 transport -- Part 2. In vivo measurement of O2 -- Part 3. Exercise and O2 transport -- Part 4. O2 microenvironment in cancer -- Part 5. Clinical aspects of O2 transport.
  • Mitochondrial genetic abnormalities after radiation exposure -- Crediting six discoverers of oxygen -- Hypoxia in tumors: pathogenesis-related classifi cation, characterization of hypoxia subtypes, and associated biological and clinical implications -- Heterogeneity in tissue oxygenation: from physiological variability in normal tissues to pathophysiological chaos in malignant tumours -- Oxygen diffusion: an enzyme-controlled variable parameter -- Role of microvascular shunts in the loss of cerebral blood flow autoregulation -- Impact of hypoxia-related tumor acidosis on cytotoxicity of different chemotherapeutic drugs in vitro and in vivo -- The founding of ISOTT: the Shamattawa of engineering science and medical science -- A tale of two methods: combining near- infrared spectroscopy with MRI for studies of brain oxygenation and metabolism -- Advances in probes and methods for clinical EPR oximetry -- Real-time, in vivo determination of dynamic changes In lung and heart tissue oxygenation using EPR oximetry -- Modulation of hypoxia by magnetic nanoparticle hyperthermia to augment therapeutic index -- Skeletal muscle and glioma oxygenation by carbogen inhalation in rats: a longitudinal study by EPR oximetry using single-probe implantable oxygen sensors -- Recurrent low-dose chemotherapy to inhibit and oxygenate head and neck tumors -- How in vivo EPR measures and images oxygen -- What we learn from in vivo EPR oxygen images -- EPR image based oxygen movies for transient hypoxia -- Repetitive measurements of intrarenal oxygenation in vivo using L band electron paramagnetic resonance -- Quantitative hypoxia imaging for treatment planning of radiotherapy -- A new flavonoid regulates angiogenesis and reactive oxygen species production -- Angiotensin II reduces transport-dependent oxygen consumption but increases transport-independent oxygen consumption in immortalized mouse proximal tubular cells -- Investigation of cerebral autoregulation In the newborn piglet during anaesthesia and surgery -- Influence of the maternal use of labetalol on the neurogenic mechanism for cerebral autoregulation assessed by means of NIRS -- Development of a near infrared multi- wavelength, multi-channel, time-resolved spectrometer for measuring brain tissue haemodynamics and metabolism -- Simulating NIRS and MRS measurements during cerebral hypoxia-ischaemia in piglets using a computational model -- Analysis of slow wave oscillations in cerebral haemodynamics and metabolism following subarachnoid haemorrhage -- Effects of enriched environment on hippocampal neuronal cell death and neurogenesis in rat global ischemia -- Automated image analysis for diameters and branching points of cerebral penetrating arteries and veins captured with two-photon microscopy -- Cerebral hemodynamic change and metabolic alteration in severe hemorrhagic shock -- Physiological mechanism of increase In deoxy-hemoglobin concentration during neuronal activation in patients with cerebral ischemia: a simulation study with the balloon model -- Effect of blood in the cerebrospinal fluid on the accuracy of cerebral oxygenation measured by near infrared spectroscopy -- Vessel specifi c imaging of glucose transfer with fluorescent glucose analogue in anesthetized mouse cortex -- Ischemic pretreatment delays ischemic brain vasospasm Injury in gerbils -- Changes in cerebral blood oxygenation induced by active standing test in children with POTS and NMS -- Optical imaging of brain activation in Gambian infants -- Asymmetrical changes in cerebral blood oxygenation induced by an active standing test in children with postural tachycardia syndrome -- Changes of cerebral tissue oxygen saturation at sleep transitions in adolescents -- Influence of subjective happiness on the prefrontal brain activity: an fNIRS study -- Ginkobiloba extract improves working memory performance in middle-aged women: role of asymmetry of prefrontal cortex activity during a working memory task -- Bayesian prediction of anxiety level in aged people at rest using 2-channel NIRS data from prefrontal cortex -- Short-term hypoxic preconditioning improved survival following cardiac arrest and resuscitation in rats -- Venular valves and retrograde perfusion -- Monitoring of filter patency during carotid artery stenting using near-infrared spectroscopy with high time-resolution -- Use of NIRS to assess effect of training on peripheral muscle oxygenation changes in elite rugby players performing repeated supramaximal cycling tests -- Skeletal muscle deoxygenation responses during treadmill exercise in children -- Development of a hybrid microwave-optical thermoregulation monitor for the muscle -- Evaluation of a textile-based near infrared spectroscopy system in calf muscle oxygenation measurements -- Skin temperature in lower hind limb subjected to distal vein arterialization in rats.
  • Physical-chemical properties of ozone: natural production of ozone: the toxicology of ozone -- How ozone is generated and its concentrations measured? -- Preparation of ozonated water and oil for the topical therapy: ozone as a drinking water disinfectant: ozone disinfection to prevent nosocomial infections -- How does ozone act?: how and why can we avoid ozone toxicity? -- How is ozone administered? -- The actual six therapeutic modalities -- The potential toxicity of ozone: side effects and contraindications of ozonetherapy -- Is ozone really a "wonder drug"? -- The clinical applications of ozonetherapy -- The dilemma between hyperbaric oxygen therapy (HOT) and ozone therapy -- The still uncertain future of ozone therapy in medicine.

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