• 2006From: OHR
  • 2006From: Ovid
    editor-in-chief, Julia A. McMillan ; editors, Ralph D. Feigin, Catherine D. DeAngelis, M. Douglas Jones, Jr.
    The history of pediatrics in America -- The field of pediatrics -- Ethics of pediatric medicine -- Reading and keeping up with the medical literature -- Pediatric history and physical examination -- Diagnostic process -- Pharmacologic principles of drug therapy -- Complementary, alternative, holistic, and integrative medicine -- Fluid and electrolyte physiology and therapy -- Molecular genetics -- Genetics in pediatric primary care -- Evaluating and using laboratory tests -- Ambulatory care: present and future -- Feeding the healthy child -- Immunization -- Injury prevention and control -- Child maltreatment -- Newborn screening -- Congenital malformations -- Growth and metabolic adaptation of the fetus and newborn -- General obstetric care -- Fetal evaluation and prenatal diagnosis -- Management of the normal newborn -- The newborn intensive care unit -- The premature newborn -- Neonatal hyperbilirubinemia. Intrauterine growth restriction -- Follow-up of infants discharged from newborn intensive care -- Ethical issues in neonatology -- Surgical considerations and postoperative care of the newborn -- Neuroembryology -- Intraventricular hemorrhage of the preterm infant -- White matter injury in the premature infant -- Neonatal encephalopathies -- Perinatal cerebral infarction -- Neonatal seizures -- The floppy infant and the late walker -- Neonatal abstinence syndrome -- Developmental considerations -- Physiologic considerations -- Causes of respiratory distress in the newborn -- Respiratory distress syndrome -- Cystic adenomatoid malformation -- Transient tachypnea of the newborn -- Pneumonia -- Pulmonary air leaks -- Meconium aspiration syndrome -- Persistent pulmonary hypertension -- Apnea -- Bronchopulmonary dysplasia -- Cardiovascular embryology -- Epidemiology of congenital heart disease -- Cardiovascular disease in the newborn -- Cardiovascular surgery in the newborn -- Developmental disorders of gastrointestinal function -- Neonatal cholestasis -- Sucking and swallowing disorders and gastroesophageal reflux -- Distended Abdomen -- Necrotizing enterocolitis -- Short bowel syndrome. Renal and genitourinary diseases -- Neonatal endocrinology -- Infant of the diabetic mother -- Mineral metabolism in the newborn -- Urinary tract infections -- Hematopoiesis and hematologic diseases -- Malignancy in the newborn -- Dermatologic disease -- Craniofacial defects -- Eye evaluation of the newborn -- Sepsis neonatorum -- Meningitis -- Osteomyelitis and septic arthritis -- Skin and soft tissue infections -- Group B streptococcal disease -- Enterovirus -- Cytomegalovirus -- Herpes simplex virus -- Neonatal varicella-zoster virus -- Epstein-Barr virus -- Neonatal syphilis -- Rubella -- Neonatal toxoplasmosis -- Hepatitis viruses -- Neisseria gonorrhoeae -- Chlamydia trachomatis -- Genital mycoplasmas -- Nosocomial infection in the newborn -- Introduction to adolescent medicine -- Breast disorders -- Menstrual disorders -- Adolescent pregnancy and contraception -- Adolescent hypertension -- Adolescent substance abuse and other high-risk behaviors -- Sexually transmitted diseases -- Normal infant and childhood development -- Streams of development: the key to developmental assessment -- Mental retardation -- Biopsychosocial and developmental approaches in pediatrics -- Psychosocial interview. Mental disorders and psychological stress -- Disruptive behavior disorders -- Emotional disorders with childhood onset -- Depression in childhood and adolescence -- Suicide -- Somatoform and conversion disorders -- Pervasive developmental disorder and autistic disorder -- Eating disorders -- Sleep disorders -- Psychotic disorders -- Enuresis -- Encopresis -- School difficulties -- Adoption -- Child and adolescent psychiatric referral -- Selected topics in emergency medicine -- Apparent life-threatening events. Sudden Infant Death Syndrome (SIDS) -- Acute head trauma -- General principles of poisoning management -- Salicylism -- Acetaminophen overdose -- Plant poisoning -- Lead poisoning -- Minor burns -- Respiratory complications of burns and smoke inhalation (respiratory burns) -- Foreign bodies -- Oral problems -- Pediatric ophthalmology -- Pediatric dermatology -- Sports medicine -- Failure to thrive -- Fever without source -- Fever of unknown origin -- Pathogenesis of ever and its treatment -- Sepsis and septic shock -- Bacterial meningitis beyond the newborn period -- Opportunistic infections in the compromised host -- Bioterrorism -- Pediatric human immunodeficiency virus infection -- Antiretroviral therapy in pediatric acquired immunodeficiency syndrome. Prophylaxis for exposure to human immunodeficiency virus -- Mycoplasma and ureaplasma infections -- Chlamydial infections -- Rickettsial diseases -- Control of nosocomial infections -- Diagnostic microbiology for pediatric infections -- Assays for the diagnosis of infectious diseases -- Kawasaki disease -- Cardiovascular aspects of Kawasaki disease -- Aeromonas -- Actinomycosis -- Nocardiosis -- Anaerobic infections -- Bartonellosis -- Relapsing fever -- Lyme disease -- Campylobacter and helicobacter -- Cat-scratch disease -- Diphtheria -- Diarrheagenic Escherichia coli -- Haemophilas influenzae -- Legionella -- Leptospirosis -- Listeriosis -- Meningococcal infections -- Gonococcal infections -- Pasteurella multocida -- Pertussis -- Plague -- Pneumococcal infections -- Pseudomonas and related genera -- Rat-bite fever -- Salmonella infections -- Shigellosis -- Staphylococcal infections -- Group A streptococcal infections -- Tularemia -- Syphilis -- Tuberculosis -- Nontuberculous mycobacteria -- Yersinia enterocolitica -- Yersinia pseudotuberculosis -- Miscellaneous bacterial infections -- Arboviruses and related zoonotic viruses -- Coronaviruses -- Rhinoviruses -- Adenoviruses -- Influenza viruses -- Parainfluenza viruses -- Human metapneumovirus -- Respiratory syncytial virus. Parvoviruses -- Polioviruses -- Nonpolio enterovirsues and parechoviruses -- Epstein-Barr virus infection in children -- Postnatal herpes simplex virus -- Human herpesvirus type 6 -- Human herpesvirus types 7 and 8 -- Varicella-zoster virus infections -- Acquired cytomegaloviral infections -- Rubella (German measles) -- Measles (Rubeola) -- Mumps -- Polyomaviruses -- Retroviruses -- Smallpox -- Viral gastroenteritis -- Candidiasis -- The dermatophytoses -- Aspergillosis -- Coccidioidomycosis -- Cryptococcosis -- Histoplasmosis -- Sporotrichosis -- Miscellaneous fungal infections -- Entamoeba histolytica -- Babesiosis -- Cryptospordiiosis -- Giardia lamblia -- Leishmaniasis -- Malaria -- Toxoplasmosis -- The nematodes -- Toxocara infections -- The cestodes -- Schistosomiasis -- Arthropoda -- Chronic cough in children -- Bronchiolitis -- Viral and atypical pneumonia -- Hypersensitivity pneumonitis -- Pneumocystis Jiroveci pneumonia -- Bacterial pneumonia -- Laryngeal disorders -- Ciliary dyskinesia -- Cystic fibrosis -- Pulmonary hemosiderosis -- Obstructive sleep apnea syndrome -- Central hypoventilation syndromes -- Chronic diffuse interstitial lung disease in childhood. Pulmonary alveolar microlithiasis -- Emphysema -- Diseases of the pleura -- Recurrent or persistent lower respiratory tract symptoms -- The common cold -- Paranasal sinusitis -- Orofacial infections -- Pharyngitis -- Deep neck abscesses -- Otitis externa -- Otitis media -- Mastoiditis -- Uvulitis -- Life-threatening upper airway obstruction -- Croup -- Cervical lymphadenitis -- Herpangina -- Pharyngoconjunctival fever -- Parotitis -- Echocardiography and electrocardiography -- Hypertension -- Transposition of the great arteries -- Truncus arteriosus -- Tricuspid atresia -- Tetralogy of Fallot -- Double-outlet right ventricle -- Eisenmenger syndrome -- Single ventricle -- Hypoplastic left heart syndrome -- Cardiac malposition and heterotaxy -- Defects of the atrial septum, including the atrioventricular canal -- Ventricular septal defect -- Patent ductus arteriosus -- Pulmonary stenosis -- Pulmonary valve atresia with intact ventricular septum -- Coarctation of the aorta -- Anomalous pulmonary venous connections -- Congenital mitral valve disease -- Mitral valve prolapse -- Aortic arch and pulmonary artery abnormalities -- congenital coronary artery abnormalities -- Myocarditis -- Cardiomyopathy -- Infective endocarditis -- Rheumatic fever -- Rheumatic heart disease -- Abnormalities of rate and rhythm -- Therapeutic cardiac catheterization. Nutritional anemias -- Hemoglobinopathies and thalassemias -- Hemolytic anemias -- Hypoplastic and aplastic anemias -- Polycythemia -- Quantitative granulocyte disorders -- The spleen and lymph nodes -- General approaches to coagulopathies -- Disorders of platelets -- Disorders of coagulation factors -- General considerations of neoplastic diseases -- Acute lymphoblastic leukemia -- Acute myeloid leukemia -- Chronic myeloproliferative disorders -- Hematopoietic stem cell transplantation for childhood leukemias -- Hodgkin disease -- Non-Hodgkin lymphoma -- Malignant brain tumors -- Wilms tumor -- Neuroblastoma -- Soft-tissue sarcomas -- Retinoblastoma -- Malignant bone tumors -- Malignant tumors of the gastrointestinal tract, liver, and endocrine system -- Gonadal and germ cell neoplasms -- Histiocytic proliferative diseases -- Vascular malformations -- Hemangiomas and other vascular tumors of infancy -- Thymomas -- Splenic cysts -- Morphologic development of the kidney -- Disorders of renal development and anomalies of the collecting system, bladder, penis, and scrotum -- Urinary tract infection -- Chronic renal failure -- End-stage renal disease -- Renal malformations -- Glomerulonephritis and nephrotic syndrome -- Progressive hereditary nephritis. Benign familial hematuria -- Familial juvenile nephronophthisis -- Nephropathy of diabetes mellitus -- Sickle cell nephropathy -- Primary hyperoxaluria (oxalosis) -- Nail-patella syndrome (hereditary onychoosteodysplasia) -- Renal tubular acidosis -- Panproximal tubular dysfunction (Fanconi syndrome) -- Disorders of renal glucose transport -- Disorders of renal phosphate transport -- Nephrogenic diabetes insipidus -- Bartter syndrome -- Renal hypertension -- Renal vascular thrombosis -- Urolithiasis -- Normal gastrointestnal function -- Functional constipation and encopresis -- Chronic nonspecific diarrhea of childhood -- Inguinal hernia -- Gastrointestinal bleeding -- Peptic ulcer disease -- Intussusception -- Motility disorders -- Oral rehydration therapy -- Anorectal malformations -- Ulcerative colitis -- Crohn disease -- Antibiotic-associated diarrhea and colitis -- Chronic recurrent abdominal pain -- Protein-losing enteropathy -- Protein intolerance -- Eosinophilic gastrointestinal diseases -- Short bowel syndrome -- Small bowel bacterial overgrowth -- Celiac disease -- Immunodeficiency states -- Enzyme and transport defects -- Appendicitis -- Ascites -- Pancreatitis -- Disorders of the liver and biliary system -- Liver abscess -- Cholecystitis -- Cirrhosis -- Portal hypertension -- Hepatic steatosis -- Parathyroid glands. Puberty and gonadal disorders -- Growth, growth hormone, and pituitary disorders -- Childhood obesity -- Neuroendocrine disorders -- Type 1 (insulin-dependent) diabetes mellitus -- Type 2 diabetes mellitus -- Thyroid gland -- Adrenal cortex -- Adrenal medulla -- Introduction to inborn errors of metabolism -- Disorders of transport -- Disorders of amino acid and organic acid metabolism -- Disorders of mitochondrial fatty acid oxidation -- Disorders of carbohydrate metabolism -- Disorders of lipoproteins -- Lysosomal storage disorders -- Peroxisomal disorders -- Disorders of purine and pyrimidine metabolism -- Heritable disorders of connective tissue -- Inborn errors associated with faulty bone mineralization -- Evaluation of the child with neurologic disease -- Developmental defects -- Cerebral palsy -- Acute encephalopathies -- Static encephalopathy -- Idiopathic intracranial hypertension -- Cerebrovascular disease in childhood -- Epilepsy -- Status epilepticus -- Febrile seizures -- The comatose child -- Reye syndrome -- Disorders of the anterior horn cell -- Peripheral neuropathies -- Diseases of the neuromuscular junction. Hereditary and acquired types of myopathy -- Slow virus infections and transmissible spongiform encephalopathies of the central nervous system -- Leukodystrophies -- Metabolic encephalopathies -- Rett syndrome -- Basal ganglia and neurotransmitter disorders -- Diseases with astrocyte abnormalities -- Phakomatoses and other neurocutaneous syndromes -- Headache -- Unclassified nervous system disorders: Alpers disease -- General considerations of allergies in childhood -- Asthma -- Urticaria and angioedema -- Food allergies -- Atopic dermatitis -- Allergic rhinitis and associated disorders -- Insect sting allergy -- The immune system -- Clinical presentation of primary immunodeficiency diseases -- Disorders of humoral immunity -- Complement deficiencies -- Functional disorders of granulocytes -- Combined immunodeficiency diseases -- Bone, joint, and muscle problems -- Skeletal dysplasias. Rheumatic diseases of childhood -- Amyloidosis -- Henoch-Schönlein syndrome -- Intensive care: physical environment -- Electrocardiographic and respiratory monitors -- Infusion devices -- Temperature-controlling and temperature-sensing devices -- Vascular catheters -- Measurement of cardiac output -- Echocardiography -- Intracranial pressure measurements -- Intubation -- Extubation -- Tracheostomy -- Abdominal paracentesis -- Acute peritoneal dialysis -- Acute hemodialysis -- Continuous renal replacement therapy -- ontinuous drip feeding -- Shock -- Acute respiratory distress syndrome -- Acute hepatic failure -- Acute renal failure -- Hemolytic-uremic syndrome -- Syndrome of inappropriate secretion of antidiuretic hormone -- Care of children with solid-organ transplants -- Multiple trauma.
  • 2007From: ScienceDirect
    edited by Dieter Häussinger, Helmut Sies.
    Water compartments in cells / G. D. Fullerton ... [et al.] -- Yeast osmoregulation / S. Hohmann ... [et al.] -- Physiological analysis of bacterial mechanosensitive channels / I. R. Booth ... [et al.] -- Control of cell cycle in response to osmostress: Lessons from yeast / J. Clotet ... [et al.] -- Bacterial osmosensing transporters / J. M. Wood -- Plant gene networks in osmotic stress response: From genes to regulatory networks / L. S. Tran ... [et al.] -- Osmosensing by integrins in rat liver / F. Schliess ... [et al.] -- Hyperosmotic activation of the CD95 system / R. Reinehr ... [et al.] -- New approaches for determining apoptotic volume decrease in cells / C. D. Bortner ... [et al.] -- Transient receptor potential channels in mechanosensing and cell volume regulation / S. F. Pedersen ... [et al.] -- Cell volume regulatory ion channels in cell proliferation and cell death / F. Lang ... [et al.] -- Actin cytoskeleton architecture and signaling in osmosensing / E. A. Papakonstanti ... [et al.] -- Osmotic stress and DNA damage / N. I. Dmitrieva ... [et al.] -- Transcriptional activator tone-binding protein in cellular protection and differentiation / J. A. Kim ... [et al.] -- Desiccation response of mammalian cells: Anhydrosignaling / Z. Huang ... [et al.] -- Tonicity-regulated gene expression / J. D. Ferraris ... [et al.] -- Hyperosmotic induction of mitogen-activated protein kinase scaffolding / T. L. Hilder ... [et al.] -- Osmoregulation of bile formation / R. Kubitz ... [et al.] -- Osmosignaling and volume regulation in intestinal epithelial cells / C. H. Lim ... [et al.] -- Osmotic regulation of cellular glucose uptake / P. Gual ... [et al.] -- Effects of osmolytes on protein folding and aggregation in cells / Z. Ignatova ... [et al.] -- Simulations of macromolecules in protective and denaturing osmolytes: Properties of mixed solvent systems and their effects on water and protein structure and dynamics / D. A. Beck ... [et al.] -- Application of the transfer model to understand how naturally occurring osmolytes affect protein stability / M. Auton ... [et al.] -- Mechanisms of high salinity tolerance in plants / N. Tuteja -- Phenotype of the taurine transporter knockout mouse / U. Warskulat ... [et al.] -- Molecular basis of osmolyte effects on protein and metabolites / J. Rosgen -- Methods of changing biopolymer volume fraction and cytoplasmic solute concentrations for in vivo biophysical studies / M. C. Konopka ... [et al.] -- Characterization of plant aquaporins / R. Kaldenhoff ... [et al.].
    Also available: Print – 2007
  • Kravkov, Nikolaĭ Pavlovich.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2008From: NICE
    The summary of the published clinical guideline on Osteoarthritis. It links to the published guidance and key documents.
  • 2015From: Springer
    Mohit Kapoor, Nizar N. Mahomed, editors.
    1. Pathogenesis of Osteoarthritis -- 2. Hip and Knee Osteoarthritis -- 3. Shoulder and Elbow Osteoarthritis -- 4. Lumbar Spine Osteoarthritis -- 5. Ankle Osteoarthritis -- 6. Hand and Wrist Osteoarthritis -- 7. Imaging in Osteoarthritis -- 8. Osteoarthritis : Joint Conservation Strategies -- 9. Osteoarthritis Biomarkers -- 10. Drug/Agent Treatments for Osteoarthritis : Present and Future -- 11. Safety Profile of Current OA Therapies : Evidence from Clinical Trials -- 12. Regenerative Medicine Approaches for Treatment of Osteoarthritis -- 13. Precision Medicine for Osteoarthritis.
  • 2007From: Ovid
    Roland W. Moskowitz ... [et al.].
  • 2007From: Springer
    edited by Yongwon Choi.
    Also available: Print – 2007
  • 2010From: Springer
    Yongwon Choi, editor.
    The role of bone marrow edema and lymphangiogenesis in inflammatory-erosive arthritis / Edward M. Schwarz ... [et al.] -- Activation of [gamma][delta] T cells by bisphosphonates / Keith Thompson ... [et al.] -- Identification of cell cycle-arrested quiescent osteoclast precursors in vivo / Naoyuki Takahashi ... [et al.] -- Megakaryocyte-bone cell interactions / Melissa A. Kacena and Wendy A. Ciovacco -- Regulation of osteoblast differentiation by Runx2 / Toshihisa Komori -- Communication between ephrinB2 and ephB4 within the osteoblast lineage / T.J. Martin ... [et al.] -- The unexpected link between osteoclasts and the immune system / Hiroshi Takayanagi -- NFATc1 in inflammatory and musculoskeletal conditions / Antonios O. Aliprantis and Laurie H. Glimcher -- Novel functions of RANK(L) signaling in the immune system / Andreas Leibbrandt and Josef M. Penninger -- Eph and ephrin interactions in bone / Koichi Matsuo -- How do bone cells secret proteins? / Haibo Zhao ... [et al.] -- Regulation of osteoclast apoptosis by Bcl-2 family protein Bim and caspase-3 / Sakae Tanaka ... [et al.] -- Regulation of bone formation and immune cell development by Schnurri proteins / Dallas C. Jones and Laurie H. Glimcher.
    Also available: Print – 2010
  • 2013From: Springer
    edited by Yongwon Choi.
    Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. It has become increasingly clear that critical interactions between these two organ systems frequently occur. This is particularly true for the development of immune cells in the bone marrow and for the function of bone cells in health and disease. However, because these two disciplines developed independently, investigators in each don't always fully appreciate the significance of the other. This book is meant to provide a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. Approximately half the book will focus on the role that osteoimmunology plays in the development of human diseases.
  • 2011From: ScienceDirect
    edited by Joseph Lorenzo ... [et al.].
    1. Overview: The Developing Field of Osteoimmunology / Joseph Lorenzo, Yongwon Choi, Mark Horowitz, Hiroshi Takayanagi -- 2. Origins of Osteoclasts / Deborah L. Galson, G. David Roodman -- 3. The Adaptive Immune Response / David G. Hesslein, Hector L. Aguila, Mark C. Horowitz -- 4. The Role of Bone Cells in Establishing the Hematopoietic Stem Cell Niche / Joy Y. Wu, Henry M. Kronenberg -- 5. Osteoblasts and their Signaling Pathways: New Frontiers for Linkage to the Immune System / Jane B. Lian, Ellen M. Gravallese, Gary S. Stein -- 6. The Osteoclast: The Pioneer of Osteoimmunology / Roberta Faccio, Yongwon Choi, Steven L. Teitelbaum, Hiroshi Takayanagi -- 7. The Effects of Immune Cell Products (Cytokines and Hematopoietic Cell Growth Factors) on Bone Cells / Joseph Lorenzo -- 8. Interactions Among Osteoblasts, Osteoclasts, and Other Cells in Bone / T. John Martin, Natalie A. Sims, Julian M.W. Quinn -- 9. The Role of the Immune System in the Development of Osteoporosis / Ulrike I. Mödder, B. Lawrence Riggs, Sundeep Khosla -- 10. The Role of the Immune System in the Bone Loss of Inflammatory Arthritis / Steven R. Goldring, Georg Schett -- 11. Inflammatory Bowel Disease and Bone / Francisco A. Sylvester, Anthony T. Vella -- 12. The Role of the Immune System in Fracture Healing / Brandon M. Steen, Louis C. Gerstenfeld, Thomas A. Einhorn -- 13. The Role of the Immune System and Bone Cells in Acute and Chronic Osteomyelitis / Brendan F. Boyce, Lianping Xing, Edward M. Schwarz -- 14. The Role of the Immune System in Hematologic Malignancies that Affect Bone / Jessica A. Fowler, Claire M. Edwards, Gregory R. Mundy -- 15. Osteoimmunology in the Oral Cavity (Periodontal Disease, Lesions of Endodontic Origin and Orthodontic Tooth Movement) / Dana T. Graves, Rayyan A. Kayal, Thomas Oates, Gustavo P. Garlet.
  • 2011From: Springer
    Francesco Chiappelli.
  • 2015From: Springer
    Troy J. Boffeli, editor.
  • 2009From: Springer
    Marc M. Baltensperger, Gerold K.H. Eyrich (eds.) ; foreword by Robert E. Marx.
  • 2014From: Springer
    Kyung-Hoi Koo, Michael A. Mont, Lynne C Jones, editors.
    Part I. History -- 1. Osteonecrosis: Historical Perspective / Marvin E. Steinberg and David R. Steinberg -- Part II. Anatomy and Blood Flow -- 2. Vascular Anatomy and Blood Supply to the Femoral Head / Marcin Zlotorowicz and Jaroslaw Czubak -- 3. Ischemia and Reperfusion Injury in Bone / Howard Winet -- Part III. Epidemiology -- 4. The Prevalence of Osteonecrosis in Different Parts of the World / A.C. Gosling-Gardeniers, W.H.C. Rijnen, and J.W.M. Gardeniers -- 5. Epidemiology of Osteonecrosis in the USA / Sameer M. Naranje and Edward Y. Cheng -- 6. The Epidemiology of Osteonecrosis in Japan / Takuaki Yamamoto, Ryosuke Yamaguchi, and Yukihide Iwamoto -- 7. Epidemiology of Osteonecrosis of the Femoral Head in South Korea / Joon Soon Kang and Kee Hyung Rhyu --8. Current Trends of Osteonecrosis of the Femoral Head in Taiwan and China / Fang-Tsai Lee, Tso-Chiang Ma, and Mel S. Lee -- Part IV. Etiology -- 9. Genetic Studies in Osteonecrosis of the Femoral Head / Shin-Yoon Kim and Tae-Ho Kim -- 10. Osteonecrosis and Intravascular Coagulation Revisited / Lynne C. Jones and Deborah McK. Ciombor -- 11. Glucocorticoids (as an Etiologic Factor) / Eun Young Lee and Yun Jong Lee -- 12. Corticosteroid Usage and Osteonecrosis of the Hip / Jeffrey J. Cherian, Bhaveen H. Kapadia, Samik Banerjee, Julio J. Jauregui, and Michael A. Mont -- 13. Alcohol / Wakaba Fukushima and Yoshio Hirota -- 14. Traumatic Avascular Necrosis of the Femoral Head / Simon Damian Steppacher, Pascal Cyrill Haefeli, Helen Anwander, Klaus Arno Siebenrock, and Moritz Tannast -- 15. Posttraumatic Osteonecrosis of the Femoral Head / Taek Rim Yoon and Ha Sung Kim -- 16. Osteonecrosis in Sickle-Cell Disease / Philippe Hernigou and Gildasio Daltro -- 17. Autoimmune Disease (SLE, Antiphospholipid Syndrome), Posttransplantation (Kidney, Liver, Heart, Bone Marrow), and Other Risk Factors (Chemotherapy, Caisson Disease, Radiation, Pancreatitis, Gaucher's Disease) / Jeong Joon Yoo -- Part V. Pathology -- 18. Pathophysiology of Ischemic Diseases of the Hip: Osteonecrosis, Borderline Necrosis, and Bone Marrow Edema Syndrome / Kyung-Hoi Koo, Young-Kyun Lee, and Yun Jong Lee -- 19. The Pathology of Osteonecrosis of the Femoral Head / Takuaki Yamamoto -- Part VI. Clinical Manifestation -- 20. Natural History of Osteonecrosis / Samik Banerjee, Bhaveen H. Kapadia, Julio J. Jauregui, Jeffrey J. Cherian, and Michael A. Mont -- 21. Causes of Pain in Early and Advanced Stage Osteonecrosis / Vivek S. Jagadale and Edward Y. Cheng -- 22. Accumulation of Necrotic Fatty Marrow in Osteonecrotic Hips Mimicking Septic Arthritis / Tae-Young Kim, Kyung-Hoi Koo, and Javad Parvizi -- Part VII. Imaging Diagnosis -- 23. Radiography, MRI, CT, Bone Scan, and PET-CT / Kyung Nam Ryu, Wook Jin, and Ji Seon Park -- Part VIII. Staging and Classification -- 24. Ficat Staging System / Kyung-Hoi Koo -- 25. The University of Pennsylvania Classification of Osteonecrosis / David R. Steinberg and Marvin E. Steinberg -- 26. Natural Course and the JIC Classification of Osteonecrosis of the Femoral Head / Nobuhiko Sugano and Kenji Ohzono -- 27. Modified Kerboul Classification System of Necrotic Extent Using MRI / Yong-Chan Ha, Young-Kyun Lee, and Kyung-Hoi Koo -- 28. The ARCO Staging System: Generation and Evolution Since 1991 / J.W.M. Gardeniers, A.C. Gosling-Gardeniers, and W.H.C. Rijnen -- Part IX. Differential Diagnosis -- 29. Subchondral Stress Fracture of the Femoral Head / Hee Joong Kim, Jeong Joon Yoo, and Pil Whan Yoon -- 30. Bone Marrow Edema Syndrome of the Hip / Young-Kyun Lee and Kyung-Hoi Koo -- 31. Distinguishing Bone Marrow Edema Syndrome from Osteonecrosis / Marc W. Hungerford and Kyung-Hoi Koo -- Part X. Non-surgical Treatments -- 32. Treatment of Osteonecrosis of the Hip and Knee with Enoxaparin / Charles J. Glueck, Richard A. Freiberg, and Ping Wang -- 33. The Role of Coagulopathy in the Pathogenesis and Prevention of Corticosteroid-Induced Osteonecrosis / Takuaki Yamamoto, Goro Motomura, Ryosuke Yamaguchi, and Yukihide Iwamoto -- 34. Lipid-Lowering Agents and Their Effects on Osteonecrosis: Pros and Cons / Abdurrahman Kandil and Quanjun Cui -- 35. Is There a Role for BMPs in the Treatment of Osteonecrosis? / Philipp Leucht and Stuart B. Goodman -- 36. Alendronate in the Prevention of Collapse of the Femoral Head in Nontraumatic Osteonecrosis / Chung-Hwan Chen and Gwo-Jaw Wang -- 37. New Therapies of Bone Necrosis / Wolf Drescher, Matthias Knobe, Wolfgang Wagner, and Thomas Pufe -- Part XI. Surgical Treatments -- 38. Principles of Core Decompression for Osteonecrosis of the Hip / Bhaveen H. Kapadia, Samik Banerjee, Jeffrey J. Cherian, Julio J. Jauregui and Michael A. Mont -- 39. Stem Cells in Osteonecrosis: Cons / Anjan P. Kaushik, Anusuya Das, and Quanjun Cui -- 40. Cement Techniques in Hip Osteonecrosis with Collapse: From Traditional Methyl Methacrylate to Bone Substitutes and Stem Cells / Philippe Hernigou and Gildasio Daltro -- 41. Impaction Bone Grafting / Seung-Hoon Baek and Shin-Yoon Kim -- 42. Principles of Bone Grafting for Osteonecrosis of the Hip / Julio J. Jauregui, Samik Banerjee, Bhaveen H. Kapadia, Jeffrey J. Cherian, Kimona Issa, and Michael A. Mont -- 43. Vascularized Pedicle Iliac Bone Grafting for Osteonecrosis of the Femoral Head / Mel S. Lee -- 44. The Vascularized Fibular Graft in the Treatment of Osteonecrosis: Data, Dogma, and Controversies / Will Eward -- 45. Transtrochanteric Rotational Osteotomy for Femoral Head Osteonecrosis / Yong-Chan Ha, Jae-Hwi Nho, and Kyung-Hoi Koo -- 46. Posterior Rotational Osteotomy for Severe Femoral Head Osteonecrosis / Takashi Atsumi -- 47. Transtrochanteric Curved Varus Osteotomy for the Treatment of Osteonecrosis of the Femoral Head / Takuaki Yamamoto, Satoshi Ikemura, and Yukihide Iwamoto -- 48. Total Hip Arthroplasty Using Ceramic-on- Ceramic Articulation / Young-Kyun Lee, Ki-Choul Kim, Bun Jung Kang, and Kyung-Hoi Koo -- 49. Highly Crosslinked -Polyethylene Liners in Patients with Osteonecrosis of the Femoral Head in the United States and Europe / Patrick O'Toole and Javad Parvizi -- 50. Alumina Ceramic-on-Highly Cross- Linked Polyethylene Bearing in Cementless Total Hip Arthroplasty in Young Patients with Osteonecrosis of Femoral Head / Young-Hoo Kim -- 51. Hip Arthroplasty for Osteonecrosis of the Femoral Head / Harlan C. Amstutz, Michel J. Le Duff, and Mariam Al-Hamad -- 52. Resurfacing Arthroplasty for Osteonecrosis of the Femoral Head / Bernard N. Stulberg and Jayson D. Zadzilka -- Part XII. Osteonecrosis in Bones Other than the Hip -- 53. Multifocal Osteonecrosis / Samik Banerjee, Bhaveen H. Kapadia, Jeffrey J. Cherian, Julio J. Jauregui, and Michael A. Mont -- 54. Osteonecrosis of the Humeral Head / Nobuhiko Sugano -- 55. Knee Osteonecrosis / Karthik E. Ponnusamy, Savyasachi Thakkar, and Harpal S. Khanuja -- 56. Osteonecrosis of the Talus / Kyoung Min Lee, Sung Hun Won, and Moon Seok Park -- 57. Kienböck's Disease of the Lunate / Dawn M. LaPorte and Thomas J. Kim -- Part XIII. Legg-Calvé-Perthes Disease -- 58. The Epidemiology and Etiology of Perthes' Disease / Daniel C. Perry -- 59. Legg-Calvé-Perthes Disease: Pathology, Pathophysiology, and Pathogenesis of Deformity / Harry K.W. Kim -- 60. Legg-Calvé-Perthes Disease: Diagnosis, Imaging, and Classifications / Benjamin Shore and Harry K.W. Kim -- 61. Legg-Calvé-Perthes Disease: Treatments / Benjamin D. Martin and Harry K.W. Kim -- 62. Developing Medical Therapy for Legg-Calvé-Perthes' Disease / Harry K.W. Kim and David G. Little -- 63. Corticosteroid-Associated Osteonecrosis in Children / Scott Rosenfeld and Harry K.W. Kim -- Part XIV. Animal Models -- 64. Animal Models of Corticosteroid- Associated Bone Diseases / Lynne C. Jones, Michelle A. Tucci, Azeb Haile, and Dongqing Wang -- 65. Animal Models of Bone Necrosis: An Overview / Wagner Drescher, Matthias Knobe, Wolfgang Wagner, and Thomas Pufe.
  • 2000From: NLM
    prepared by Martha Glock, Kathleen A. Shanahan, Joan A. McGowan.
  • 2007From: Ovid
    Pauline M. Camacho, Paul D. Miller.
    Diagnosis -- Pathogenesis -- Assessment of fracture risk -- Bone densitometry: using dual-energy x-ray absorptiometry for monitoring -- Biochemical evaluation -- Secondary causes of osteoporosis -- Acquired vitamin D deficiency -- Treatment options -- Tailoring therapy to individual patients -- Determining success of therapy and what to do when therapy fails -- Future therapeutic options -- Case studies.
  • 2009From: Springer
    Reiner Bartl, Bertha Frisch ; in collaboration with Christoph Bartl.
  • 2013From: Springer
    Giuseppe Guglielmi, editors ; foreword by Maximilian F. Reiser.
    Osteoporosis is a serious problem worldwide, and its significance is continuing to increase as the world population grows and ages. Osteoporosis and Bone Densitometry Measurements provides a comprehensive review of the latest research on this potentially devastating condition. The book encompasses prevention, diagnosis, and therapy, providing state of the art information on each aspect. A wide range of topics are discussed, including differentiation between acute and chronic, benign and malignant vertebral fractures; the value of the WHO FRAX tool in patient evaluation; the roles of dual-energy X-ray absorptiometry, quantitative computed tomography, quantitative ultrasound, and high-resolution imaging; and the use of kyphoplasty and vertebroplasty to treat vertebral compression fractures. All chapters are written by acknowledged experts in the field.
  • 2015From: Springer Protocols
    edited by Jennifer J. Westendorf and Andre J. van Wijnen, Mayo Clinic, Rochester, MN, USA .
    Isolation of osteocytes from mature and aged murine bone / Amber Rath Stern and Lynda F. Bonewald -- Primary murine rowth plate and articular chondrocyte isolation and cell culture / Jennifer H. Jonason, Donna Hoak, and Regis J. O'Keefe -- Isolating endosteal mesenchymal progenitors from rodent long bones / Ji Zhu, Valerie A. Siclari, and Ling Qin -- Engineering cartilage tissue by pellet coculture of chondrocytes and mesenchymal stromal cells / Ling Wu, Janine N. Post, and Marcel Karperien -- Generation of induced pluripotent stem cells / David R. Deyle -- Profiling histone modifications by chromatin immunoprecipitation coupled to deep sequencing in skeletal cells / Mark B. Meyer, Nancy A. Benkusky, and J. Wesley Pike -- Identification of microRNAs in human plasma / Bram C. van der Eerden ... [and 7 others] -- Immunohistochemistry of skeletal tissues / Crystal Idleburg, Elizabeth N. DeLassus, and Deborah V. Novack -- In vivo axial loading of the mouse tibia / Katherine M. Melville, Alexander G. Robling, and Marjolein C.H. van der Meulen -- Four-point bending protocols to study the effects of dynamic strain in osteoblastic cells in vitro / Gabriel L. Galea and Joanna S. Price -- EPIC-[mu]CT imaging of articular cartilage / Angela S.P. Lin, Giuliana E. Salazar-Noratto, and Robert E. Guldberg -- Mouse models of osteoarthrits : surgical model of posttraumatic osteoarthritis induced by destabilization of the medial meniscus / Kirsty L. Culley ... [and 7 others] -- Assessment of knee joint pain in experimental rodent models of osteoarthritis / Margaret J. Piel, Jeffrey S. Kroin, and Hee-Jeong Im -- Induction of fully stabilized cortical bone defects to study intramembranous bone regeneration / Meghan E. McGee-Lawrence and David F. Razidlo -- Surgical procedures and experimental outcomes of closed fractures in rodent models / Hicham Drissi and David N. Paglia.
  • 2012From: NICE
    The summary of the published clinical guideline on Osteoporosis fragility fracture. It links to the published guidance and key documents.
  • 2010From: ScienceDirect
    2010From: ClinicalKey
    [edited by] Eric S. Orwoll, John P. Bilezikian, Dirk Vanderschueren.
    Section 1. Essentials of bone biology -- The biochemistry of bone : composition and organization / Adele L. Boskey -- Bone remodeling : cellular activities in bone / David W. Dempster, Hua Zhou, Shi Shou Lu -- Assessment of bone turnover in men using biochemical markers / Patrick Garnero, Pawel Szulc -- Fundamentals of mineral homeostasis / David A. Hanley, K. Shawn Davison -- The mechanical properties of bone / David P. Fyhrie -- Essentials of bone biology : assessment of bone architecture / Thomas F. Lang -- Section 2. Development and growth of the male skeleton -- Skeletal growth in males / Qingju Wang, Ego Seeman -- Pubertal growth of the male skeleton / Vincent Gilsanz, Stefano Mora -- The effects of sex steroids on bone growth / Giampiero I. Baroncelli, Silvano Bertelloni -- Nutritional basis of skeletal growth / Connie M. Weaver, Elizabeth Haney -- Physical activity and skeletal growth / Heather M. Macdonald, Heather A. McKay, Melonie Burrows -- Section 3. Skeletal genetics -- The genetics of peak bone mass / Luigi Gennari, Robert F. Klein, Serge Ferrari -- Section 4. Aging and the male skeleton -- Age-related changes in bone remodeling and microarchitecture / Roger Zebaze, Ego Seeman -- Markers of bone remodeling and the aging skeleton / Serge Cremers, Christian Meier, Markus J. Seibel -- Alterations in mineral metabolism in the aging male / Shonni J. Silverberg, Bismruta Misra -- Changes in bone size and geometry with aging / Pawel Szulc -- Aging and bone loss / Steven Boonen ... [et al.] -- The effect of age on material properties / Charles H. Turner, Matthew R. Allen, David B. -- Section 5. Nutritional issues -- Calcium, bone strength and fractures / Laura A.G. Armas, Robert P. Heaney, Joan M. Lappe -- Vitamin D and bone / Roger Bouillon ... [et al.] -- Role of dietary protein in bone growth and bone loss / Rene Rizzoli -- Section 6. Sex steroids and the skeleton in men -- Section 7. Fractures in men -- Section 8. Metabolic bone disease in men -- Section 9. Diagnostic approach -- Section 10. Therapy.
  • 2009From: Springer
    Gustavo Duque, Douglas P. Kiel, editors.
    Also available: Print – 2008
  • 2016From: Springer
    Yoichi Shimada, Naohisa Miyakoshi, editors.
    Part I Basic Research and Assessments -- Chapter 1 Skeletal Adaptation to Mechanical Strain: A Key Role in Osteoporosis -- Chapter 2 Osteoclast -- Mediated Pain in Osteoporosis -- Chapter 3 Collagen Crosslinks as a Determinant of Bone Quality -- Chapter 4 Assessment of Femoral Geometric Strength in Osteoporosis Using Hip Structure Analysis -- Chapter 5 Vertebral Strength Changes as Assessed by Finite Element Analysis -- Part II Factors Affecting Osteoporosis -- Chapter 6 The Geometry of Lower Extremity and Atypical Femoral Fractures -- Chapter 7 Spondylosis and Osteoporotic Vertebral Fractures -- Chapter 8 Sarcopenia and Osteoporosis -- Part III Clinical Applications of Antiosteoporotic Agents -- Chapter 9 Effects of Vitamin D on Bone and Skeletal Muscle -- Chapter 10 Applications of Teriparatide for Fracture Repair and Osteosynthetic Surgery in Osteoporosis -- Part IV Exercise and Osteoporosis -- Chapter 11 Exercise and Fall Prevention -- Chapter 12 Back Extensor Strengthening Exercise and Osteoporosis.
  • v. 1-2, 2008From: ScienceDirect
    edited by Robert Marcus, David Feldman, Dorothy A. Nelson, Clifford J. Rosen.
    Also available: Print – v. 1-2, 2008.
  • 2011From: Springer
    Gustavo Duque, Ken Watanabe (editors).
    How to Select Your Animal Model for Osteoporosis Research / A. Simon Turner -- Skeletal Phenotyping in Rodents: Tissue Isolation and Manipulation / Janet E. Henderson, Chan Gao and Edward J. Harvey -- Methods in Bone Biology in Animals: Biomechanics / José B. Volpon and Antonio C. Shimano -- Methods in Bone Histomorphometry for Animal Models / Natalie Dion, Audray Fortin and Louis-Georges Ste-Marie -- Methods in Bone Biology in Animals: Imaging / Blaine A. Christiansen and Mary L. Bouxsein -- Methods in Bone Biology in Animals: Biochemical Markers / Markus Herrmann -- Methods in Bone Biology: Cancer and Bone / Yu Zheng, Markus J. Seibel and Hong Zhou -- How to Test Osteoporosis Treatments in Experimental Animals / Robert J. van ʻt Hof -- The Ovariectomized Mice and Rats / Jameela Banu -- Classical Models of Senile Osteoporosis / Ken Watanabe -- Animal Models of Premature Aging / Wei Li and Gustavo Duque -- Nonhuman Primate Models of Osteoporosis / Susan Y. Smith, Aurore Varela and Jacquelin Jolette -- Other Large Animal Models / Susan Reinwald and David B. Burr -- Mouse models for the Study of Fracture Healing and Bone Regeneration / Joerg H. Holstein, Patric Garcia, Tina Histing, Moritz Klein and Steven C. Becker, et al.
  • 2008From: Springer Protocols
    [edited by] Jennifer J. Westendorf.
  • v.1-2, 2013From: ScienceDirect
    2013From: ClinicalKey
    edited by Robert Marcus, David Feldman, David W. Dempster, Marjorie Luckey, Jane A. Cauley.
    Volume 1. I. Introduction: The bone organ system : form and function / Elise F. Morgan, George L. Barnes, Thomas A. Einhorn ; The nature of osteoporosis / Robert Marcus, David W. Dempster, Mary L. Bouxsein ; Reflections on osteoporosis / B.E. Christopher Nordin ; Reflections on development of concepts of intercellular communication in bone / T. John Martin ; Osteo-odyssey : a memoir / Paula H. Stern -- II. Cellular, molecular, and develomental biology of bone: Development of the skeleton / Sylvain Provot [and 3 others] ; The skeletal stem cell / Dongsu Park [and 3 others] ; Osteoclast biology / Timothy R. Arnett ; Osteoblast biology / Johannes P.T.M. van Leeuwen [and 4 others] ; Osteocyte biology / Lynda F. Bonewald ; The regulatory role of matrix protein in mineralization of bone / Adele L. Boskey, Pamela Gehron Robey -- III. Skeletal hormones and regulatory factors: Parathyroid hormone and parathyroid hormone-related protein / Robert A. Nissenson ; Vitamin D : biology, actions, and clinical implications / David Feldman, Aruna V. Krishnan, Srilatha Swami ; Regulation of bone cell function by estrogens / Suzanne E. Wardell, Donald P. McDonnell, Erik R. Nelson ; Androgens and skeletal biology : basic mechanisms / Kristine M. Wiren ; Phosphatonins / Peter J. Tebben, Theresa J. Berndt, Rajiv Kumar ; Skeletal growth factors / Ernesto Canalis ; Wnt signaling in skeletal homeostasis and diseases / Francesca Gori, Roland Baron -- IV. Skeletal structure and biomechanics: The mechanical behavior of bone / Lamya Karim [and 3 others] ; Cellular and molecular mechanotransduction in bone / Julia C. Chen, Alesha B. Castillo, Christopher R. Jacobs ; Adaptation of skeletal structure to mechanical loading / Marjolein C.H. van der Meulen, Christopher J. Hernandez ; Biomechanics of hip and vertebral fractures / Denise E. Anderson, Alexander G. Bruno, Mary L. Bouxsein ; Prevention of osteoporosis by physical signals : defining a potential role for nondrug strategies in the treatment of musculoskeletal injury and disease / Clinton T. Rubin [and and 3 others] -- V. Epidemiology of osteoporosis: Epidemiologic methods in studies of osteoporosis / Kristine E. Ensrud, Brent C. Taylor ; Genetic determinants of osteoporosis / André G. Uitterlinden, M. Carola Zillikens, Fernando Rivadeneira ; Race, ethnicity, and osteoporosis / Jane A. Cauley, Dorothy A. Nelson ; Geographic variability in hip and vertebral fractures / Ghada Ballane [and 3 others] ; Nutrition and risk for osteoporosis / Robert P. Heaney ; Physical activity and exercise in the maintenance of the adult skeleton and the prevention of osteoporotic fractures / Dennis R. Taaffe [and 4 others] ; Premenopausal reproductive and hormonal characteristics and the risk for osteoporosis / John F. Randolph Jr., Maryfran R. Sowers ; Clinical and epidemiological studies : skeletal changes across menopause / Jane A. Cauley, Michelle E. Danielson, Gail A. Greendale ; Osteoporosis in men: epidemiology, pathophysiology, and clinical characterization / Eric S. Orwoll, Dirk Vanderschueren, Steven Boonen ; Falls as risk factors for fracture / Sarah D. Berry, Douglas P. Kiel ; Nonskeletal risk factors for osteoporosis and fractures / Jeri W. Nieves ; Outcomes following osteoporotic fractures / Jacqueline R. Center -- VI. General pathophysiology of osteoporosis: Skeletal heterogeneity and the purposes of bone remodeling : implications for the understanding of osteoporosis /A. Michael Parfitt ; On the evolution and contemporary roles of bone remodeling / Paul Kostenuik ; Cytokines and the pathogenesis of osteoporosis / Joseph Lorenzo ; Animal models for osteoporosis / Urszula T. Iwaniec, Russell T. Turner ; Bone and fat / Francisco J.A. de Paula [and 3 others] ; Bone mineral acquisition in utero and during infancy and childhood / Linda A. DiMeglio, Mary B. Leonard ; Bone acquisition in adolescence / Heather M. MacDonald, Christa L. Hoy, Heather A. McKay -- Volume 2. Osteoporosis in childhood and adolescence / Leanne Ward, M. Zulf Mughal, Laura K. Bachrach ; Osteoporosis associated with pregnancy / Rachel B. Wagman, Robert Marcus ; Osteoporosis in premenopausal women / Adi Cohen ; Estrogen deficiency, postmenopausal osteoporosis, and age-related bone loss / Sundeep Khosla, Roberto Pacifici --VII. Spectrum of secondary osteoporosis: Immobilization osteoporosis / William A. Bauman, Christopher P. Cardozo ; Osteoporosis associated with illnesses and medications / Elizabeth Shane, Robert Marcus ; Glucocorticoid-induced osteoporosis / Robert A. Adler, Robert S. Weinstein, Kenneth G. Saag ; Anticonvulsant-related bone disease / Alison M. Pack ; Thyroid hormone and the skeleton / Daniel Baran ; The skeletal actions of parathyroid hormone in primary hyperparathyroidism and in osteoporosis / John P. Bilezikian, Lorraine A. Fitzpatrick, Shonni J. Silverberg ; Osteogenesis imperfecta and other defects of bone development as occasional causes of adult osteoporosis / Jay R. Shapiro ; HIV and osteoporosis / Todd T. Brown, Michael T. Yin ; Obesity, diabetes, and fractures / Melissa Premaor, Juliet Compston ; Osteoporosis in organ transplant patients / Emily Stein, Elizabeth Shane ; Osteoporosis associated with rheumatologic disorders / Steven R. Goldring ; Osteoporosis associated with chronic kidney disease / Susan M. Ott, Grahame Elder ; Oral bone loss and systemic osteoporosis : weighing the risk benefit ratio of treatment / Marjorie K. Jeffcoat -- VIII. Cancer and osteoporosis: Cancer treatment-induced bone loss in patients with breast cancer : pathophysiology and clinical perspectives / Allan Lipton, Roger Dansey, Robert Coleman ; Pathophysiology-prostate cancer / Philip J. Saylor, matthew R. Smith ; Mechanisms of bone destruction in myeloma / Rebecca Silbermann, G. David Roodman --IX. Diagnosis and evaluation: Evaluation of the patient at risk for osteoporosis / E. Michael Lewiecki ; Imaging of osteoporosis / James F. Griffith, Harry K. Genant ; Osteoporosis : who should be treated? Who should be screened? / Cynthia A. Stuenkel, Bruce Ettinger ; Clinical use of bone densitometry / Sydney Lou Bonnick, Paul Miller ; Biochemical markers of bone turnover in osteoporosis / Pawel Szulc, Douglas C. Bauer ; Fracture risk assessment : the development and application of FRAX® / John A. Kanis [and 3 others] -- X. Patient management: Orthopedic aspects of osteoporosis / Susan V. Bukata ; Falls prevention interventions / Kim Delbaere, Catherine Sherrington, Stephen R. Lord ; Physical therapy, physical modalities, and exercise regimens in the management of osteoporosis / Susan B. Broy, Karen L. Kemmis ; Calcium in the treatment of osteoporosis / Robert P. Heaney ; Vitamin D and its metabolites and analogs in the management of osteoporosis / Roger Bouillon, Ian R. Reid ; Alternative therapy through nutrients and nutraceuticals / Jeri W. Nieves -- XI. Pharmacotherapeutics: Design considerations for clinical investigations of osteoporosis / Robert P. Heaney ; Lessons from bone histomorphometry on the mechanisms of action of osteoporosis drugs / Hua Zhou, David W. Dempster ; -- Estrogen and estrogen analogs for prevention and treatment of osteoporosis / Margery L.S. Gass, Sobia Khan ; Androgens / Mona Al Mukaddam, Peter J. Snyder ; Calcitonin in osteoporosis / Roberto Civitelli ; Bisphosphonates : pharmacology and use in the treatment of osteoporosis / Dima L. Diab, Nelson B. Watts, Paul D. Miller ; Osteonecrosis of the jaw and atypical femoral fractures / Elizabeth Shane, Sundeep Khosla, David Burr ; Condition critical : compliance and persistence with osteoporosis medications / Deborah T. Gold ; Denosumab for the treatment of osteoporosis / Michael R. McClung ; Strontium ranelate in the prevention of osteoporotic fractures / René Rizzoli ; Parathyroid hormone treatment for osteoporosis / Felicia Cosman, Robert Lindsay ; New approaches to osteoporosis therapeutics /Aline Costa [and 3 others] ; The past, present, and uncertain future of therapeutic innovation in osteoporosis /Hunter Heath III.
    Also available: Print – v. 1-2, 2013.
  • 2000From: ScienceDirect
    edited by Louis V. Avioli.
    Ch. 1. The necessity of a managed care approach for osteoporosis -- Ch. 2. Effects of aging on bone structure and metabolism -- Ch. 3. The genetics of osteoporosis -- Ch. 4. Bone mass measurement techniques in clinical practice -- Ch. 5. Biochemical markers of bone turnover -- Ch. 6. Calcium, vitamin D, and bone metabolism -- Ch. 7. Estrogens and selective estrogen receptor modulators for prevention and treatment of osteoporosis -- Ch. 8. Bisphosphonate treatment for osteoporosis -- Ch. 9. Calcitonin treatment in postmenopausal osteoporosis -- Ch. 10. Therapy with vitamin D metabolites, sodium fluoride, thiazides, and isoflavones -- Ch. 11. Orthopedics and the osteoporotic syndrome -- Ch. 12. Glucocorticoid-related osteoporosis -- Ch. 13. Osteoporosis and the bone biopsy.
    Also available: Print – 2000
  • 2016From: Springer
    Takafumi Ueda, Akira Kawai, editors.
    Part I: Basic Research and Experimental Therapy -- Chapter 1. Genetics of Osteosarcoma -- Chapter 2. Basic Research for Osteosarcoma Lung Metastasis (LM8) -- Chapter 3. Immunotherapy for Osteosarcoma -- Part II: Clinical Features -- Chapter 4. Outcome of Treatment for Osteosarcoma of the Extremities over the Last 20 Years: Report from 11 Referral Centers in Japan -- Chapter 5. Osteosarcoma in the Elderly: Clinical Features and Outcome -- Chapter 6. Prognosti c Factors for Osteosarcoma Patients -- Part III: Chemotherapy -- Chapter 7. Neoadjuvant Chemotherapy Developed in Japan -- Chapter 8. Neoadjuvant Chemotherapy (OOS-A, B, C, D regimens) -- Chapter 9. Caffeine-Potentiated Chemotherapy for Osteosarcoma -- Part IV: Surgery -- Chapter 10. Endoprosthetic Reconstruction for Extremity Osteosarcoma -- Chapter 11. Limb-Salvage Surgery and Reconstruction for Skeletally Immatur Childhood Osteosarcoma: Extendible Endoprostheses -- Chapter 12. Limb-Salvage Surgery for Pelvic Osteosarcoma -- Chapter 13. Management of Postoperative Infection after Limb Salvage Surgery in Osteosarcoma Patients -- Part V: Surgery : Biological Reconstruction -- Chapter 14. Biological Reconstruction for Extremity Osteosarcoma: Long Term Results and Current Concept of Intraoperative Extracorporeal Irradiated Bone Graft (IORBG) -- Chapter 15. Biological Reconstruction for Extremity Osteosarcoma: Pasteurized Autogenous Bone Graft -- Chapter 16. Biological Reconstruction for Extremity Osteosarcoma: Liquid Nitrogen Treated Tumor-Bearing Bone Graft -- Chapter 17. Biological Reconstruction for Extremity Osteosarcoma: Distraction Osteogenesis Technique -- Chapter 18. Limb-Saving Surgery Using In Situ Preparation (ISP) Method -- Part VI: Unresectable / Metastatic Disease -- Chapter 19. Carbon Ion Radiotherapy for Un resectable Osteosarcoma of the Trunk -- Chapter 20. Treatment of Osteosarcoma Patients with Pulmonary Metastasis -- Chapter 21. Long-Term Outcomes and Quality of Life (QOL) in Survivors of Pediatric and Adolescent Osteosarcoma.
  • 2017From: Thieme-Connect
    Hartmut Förstner.
    Biology of fracture healing -- Nonoperative fracture management -- Surgical fracture management -- Differential indication -- Principles of surgical management of hand fractures -- Postoperative treatment -- Implants and instruments -- Surgical approaches -- Surgical procedures.
  • 2015From: Springer
    Diego Preciado, editor.
    Otitis media (OM) is the most common diagnosis at medical visits in preschool-age children, and the literature suggests that as many as 80% of children will suffer from at least one episode. Written by acknowledged experts, this is a state of the art reference on the disesase and controversies in the field. Recent important advances in our understanding of predisposition to the disease and vaccine development are described and diagnostic best practices are presented. Otitis Media: State of the Art Concepts and Treatment is for any health care provider who works with children, and their abilit.
  • Charles D. Bluestone, Jerome O. Klein.
    PrintStatus: Not Checked OutLane Catalog Record
    Definitions, terminology, and classification. -- Anatomy. -- Physiology, pathophysiology, and pathogenesis. -- Epidemiology. -- Microbiology. -- Immunology. -- Diagnosis. -- Management. -- Complications and sequelae: intratemporal. -- Complications and sequelae: intracranial.
  • Šercer, Ante.
    PrintStatus: Not Checked OutLane Catalog Record
  • edited by George Morrison Coates, Harry P. Schenck, M. Valentine Miller.
  • 2015From: Thieme-Connect
    American Academy of Otolaryngology, Head and Neck Surgery Foundation.
  • 2001From: Karger
    volume editors, P. Tran Ba Huy, M. Toupet.
    Also available: Print – 2001
  • 2016From: ClinicalKey
    [edited by] Derald E. Brackmann, Clough Shelton, Moisés A. Arriaga.
    Otologic instrumentation -- Canalplasty for exostoses of the external auditory canal and miscellaneous auditory canal problems -- Malignancies of the temporal bone : limited and radical temporal bone resection -- Congenital malformation of the external auditory canal and middle ear -- Surgery of ventilation and mucosal disease -- Diagnosis and management of the patulous eustachian tube -- Office management of tympanic membrane perforation and the draining ear -- Tympanoplasty : outer surface grafting technique -- Cartilage tympanoplasty -- Tympanoplasty, undersurface graft technique : transcanal approach -- Tympanoplasty, undersurface graft technique : postauricular approach -- Ossicular reconstruction -- Canal wall reconstruction tympanomastoidectomy -- Surgery of acute infections and their complications -- Mastoidectomy : intact canal wall procedure -- Mastoidectomy : canal wall down procedure -- Tympanoplasty : staging and use of plastic -- Complications of surgery for chronic otitis media -- Dural herniation and cerebrospinal fluid leaks -- Total stapedectomy -- Laser stapedotomy -- Partial stapedectomy -- Laser revision stapedectomy -- Special problems of otosclerosis surgery -- Avoidance and management of complications of otosclerosis surgery -- Perilymph fistula : otic capsule defects not seen with imaging -- Management of Bell's palsy and Ramsay Hunt syndrome -- Traumatic facial paralysis -- Facial nerve tumors -- Surgery for cochlear implantation -- Pediatric auditory brainstem implantation -- Implantable hearing devices -- Bone-anchored cochlea stimulator -- Surgery of the endolymphatic sac -- Middle fossa vestibular neurectomy -- Retrolabyrinthine and retrosigmoid vestibular neurectomy -- Translabyrinthine vestibular neurectomy -- Transmastoid semicircular canal occlusion for benign paroxysmal positional vertigo and other disorders -- Cochleosacculotomy -- Transcanal labyrinthectomy -- Chemical treatment of the labyrinth -- Superior semicircular canal dehiscence syndrome -- Overview of transtemporal skull base surgery -- Operations for vascular compressive syndromes -- Drainage procedures for petrous apex lesions -- Surgery for glomus tumors and other lesions of the jugular foramen -- Rehabilitation of lower cranial nerve deficits after neurotologic skull base surgery -- Middle fossa approach -- Translabyrinthine approach -- Retrosigmoid approach to tumors of the cerebellopontine angle -- Transotic approach -- Transcochlear approach to cerebellopontine angle lesions -- Extended middle cranial fossa approach -- Anterior and subtemporal approaches to the infratemporal fossa -- Endoscopic endonasal approaches to the skull base and paranasal sinuses -- Petrosal approach -- Neurofibromatosis 2 -- Auditory implants for the central nervous system -- Extreme lateral infrajugular transcondylar approach for resection of skull base tumors -- Management of postoperative cerebrospinal fluid leak -- Care of the eye in facial paralysis and facial reanimation techniques -- Hypoglossal facial anastomosis -- Intraoperative neurophysiological monitoring -- Stereotactic radiosurgery of skull base tumors -- Vascular considerations in neurotologic surgery.
  • 2011From: Thieme eNeurosurgery
    [edited by] Oliver F. Adunka, Craig A. Buchman.
    "Expanding developments in the field have prompted a welcome increase among interested students. Interventions that were once considered somewhat esoteric by some might now be considered part of the medical mainstream. Cochlear implantation is certainly an example of such an intervention. As a consequence of these developments, a need to convey the core fund of knowledge to a larger more diverse group of trainees has arisen. With this in mind, this book was created to provide the basic concepts of otology, neurotology, and lateral skull base surgery in a rather simple, illustrated format for the new student interested in the field. While not intended to replace the more comprehensive, authoritative works in the field, this manual is meant only to create a "jumping on" point for continued study"--Provided by publisher.
  • 2007From: Karger
    volume editors, Wolfgang Arnold, Rudolf Häusler.
    Also available: Print – 2007
  • 2012From: ScienceDirect
    David Goldman.
    Neurogenetic origins of behavior -- Jinn in the genome -- 2B or not 2B? -- Stephen Mobley and his X-chromosome -- Dial multifactorial for murder : the intersection of genes and culture -- Distorted capacity I : the measure of the impaired will -- Distorted capacity II: neuropsychiatric diseases and the impaired will -- Inheritance of behavior and genes for behavior : gene wars -- Scientific and historic bases of genethics: who watches the geneticists and by what principles? -- World is double helical -- DNA, RNA, and proteins in a few easy pieces -- Stochastic brain : from DNA blueprint to behavior -- Reintroducing genes and behavior -- Warriors and worriers -- How many genes does it take to make a behavior? -- Genesis and genetics of sexual behavior -- Gene by environment interaction -- Epigenetic revolution : finding the imprint of the environment on the genome -- DNA on trial -- Parents and children : neurogenetic determinism and neurogenetic individuality -- Summing up genetic predictors of behavior.
  • Frederick M. Barken.
    PrintStatus: Not Checked OutLane Catalog Record
    The author uses his own experiences as a primary care physician to describe the state of his profession and argues that the health care system will collapse without a strong physician-patient relationship and that the role of the primary care physician must change to survive.
  • Jeffrey Levi, Laura M. Segal, Dara Alpert Lieberman, Kendra May, Rebecca St. Laurent.
    The Outbreaks report provides the public, policymakers and a broad and diverse set of groups involved in public health and the healthcare system with an objective, nonpartisan, independent analysis of the status of infectious disease policies; encourages greater transparency and accountability of the system; and recommends ways to assure the public health and healthcare systems meet today's needs and work across borders to accomplish their goals.
  • editors, Azzam F.G. Taktak and Anthony C. Fisher.
    PrintStatus: Not Checked OutLane Catalog Record
    The predictive value of detailed histological staging of surgical resection specimens in oral cancer -- Survival after treatment of intraocular melanoma -- Recent developments in relative survival analysis -- Environmental and genetic risk factors of lung cancer -- Chaos, cancer, the cellular operating system and the prediction of survival in head and neck cancer -- Flexible hazard modelling for outcome prediction in cancer: perspectives for the use of bioinformatics knowledge -- Information geometry for survival analysis and feature selection by neural networks -- Artificial neural networks used in the survival analysis of breast cancer patients: a node-negative study -- The use of artificial neural networks for the diagnosis and estimation of prognosis in cancer patients -- Machine learning contribution to solve prognostic medical problems -- Classification of brain tumors by pattern recognition of magnetic resonance imaging and spectroscopic data -- Towards automatic risk analysis for hereditary non-polyposis colorectal cancer based on pedigree data -- The impact of microarray technology in brain cancer -- The web and the new generation of medical information systems -- Geoconda: a web environment for multi-centre research -- The development and execution of medical prediction models.
  • 2012From: Springer
    S.N. Chatterjee, Keya Chaudhuri.
    Discovery of the Outer Membrane Vesicles: Revisiting Contemporary Works -- Gram-Negative Bacteria: The cell Membranes -- Factors Affecting Production of Outer Membrane Vesicles -- Outer Membrane Vesicles as Carriers of Biomaterials -- Outer Membrane Vesicles and the Biofilm Formation -- Outer Membrane Vesicles: Interaction with Prokaryotes and Eukaryotes -- Biogenesis of Outer Membrane Vesicles -- Release of Outer Membrane Vesicles: Is it a Novel Secretion Mechanism? --Outer Membrane Vesicles: Physiological Medical Applications -- Concluding Notes.
  • Gérard Battail.
    A brief overview of molecular genetics -- An overview of information theory -- More on molecular genetics -- More on information theory -- An outline of error-correcting codes -- DNA is an ephemeral memory -- A toy living world -- Subsidiary hypothesis, nested system -- Soft codes -- Biological reality conforms to the hypotheses -- Identification of genomic codes.
  • 2015From: Springer
    Robert Miller, John Dennison, editors ; translated by John Dennison and Robert Miller.
  • 1906, 1911.From: Google Books
    Fulltext (1911)From: Google Books
    Prepared for the use of students, at the Harvard medical school, Boston, 1901-02-.
    Also available: Print – 1906, 1911.
  • v. 1-3.From: Google Books
    Fulltext (v.2)From: Google Books
    Fulltext (v.3)From: Google Books
    by J.H. Wythe ... [v. 1].
    pt. 1. General histology. I. Living matter in health and disease. II. Normal and pathological histology of nutrient fluids.
    Also available: Print – v. 1-3.
  • 2015From: Springer
    editor, Alfonso M. Pluchinotta.
    The Breast Clinic -- The Asymptomatic Woman -- Anatomy, Congenital Aberrations, and Physiological Changes -- Clinical Examination of the Breast -- Imaging in Breast Related Diseases -- Breast Tissue Diagnosis -- Breast Pain -- Inflammatory Diseases of the Breast -- Benign Lesions of the Breast -- Nipple Discharge -- Miscellaneous Minor Disorders of the Breast -- Staging and Work Up of the Non Invasive Breast Cancer -- Staging and Work Up of Invasive Breast Cancer -- Breast Cancer Special Issues -- Breast Cancer in General Population -- The Role of Surgery -- The Role of Adjuvant Radiation Therapy -- The role of Adjuvant Systemic Therapy -- Male Breast Diseases -- Loco-Regional Breast Cancer Recurrences -- Follow Up.
  • 2010From: ClinicalKey
    edited by Robert E. Bristow, Deborah K. Armstrong.
    Practical, authoritative, and highly-illustrated, this volume in the brand new Early Detection and Treatment of Cancer series covers current protocols and the latest advances in diagnostic imaging and molecular and serologic markers for ovarian cancer. Apply expert advice on the best next-step plan for different presentations and tips for less invasive protocols. Get clinical, hands-on tools to help you make informed decisions on precisely what tests and imaging studies are needed for accurate diagnosis and staging. Clear figures, tables, and boxes illustrate step-by-step care of the full range of problems encountered.
  • 2013From: Springer Protocols
    edited by Anastasia Malek, Oleg Tchernitsa.
    Ovarian cancer genome / Evgeny N. Imyanitov -- Identifying associations between genomic alterations in tumors / Joshy George ... [et al.] -- Analysis of genome-wide DNA methylation profiles by BeadChip technology / Qiong Lin, Wolfgang Wagner, and Martin Zenke -- Integrative prediction of gene function and platinum-free survival from genomic and epigenetic features in ovarian cancer / Kazimierz O. Wrzeszczynski ... [et al.] -- Survival prediction based on inherited gene variation analysis / Mine S. Cicek, Matthew J. Maurer, and Ellen L. Goode -- Main principles and outcomes of DNA methylation analysis / Susan K. Murphy, Christopher F. Bassil, and Zhiqing Huang -- Methylation-specific PCR / Zhiqing Huang, Christopher F. Bassil, and Susan K. Murphy -- Bisulfite sequencing of cloned alleles / Zhiqing Huang, Christopher F. Bassil, and Susan K. Murphy -- Bisulfite pyrosequencing / Christopher F. Bassil, Zhiqing Huang, and Susan K. Murphy -- RNA networks in ovarian cancer / Anastasia Malek -- Microarray-based transcriptome profiling of ovarian cancer cells / Juan Cui, Ying Xu, and David Puett -- Deep transcriptome profiling of ovarian cancer cells using next-generation sequencing approach / Lisha Li ... [et al.] -- Assessment of mRNA splice variants by qRT-PCR / Ileabett M. Echevarria Vargas and Pablo E. Vivas-Mejía -- MicroRNA profiling in ovarian cancer / Marilena V. Iorio and Carlo M. Croce -- Detailed analysis of promoter-associated RNA / Sara Napoli -- Integrating Multiple Types of Data to Identify MicroRNA-Gene Co-modules / Shihua Zhang -- Energy metabolism and changes in cellular composition in ovarian cancer / Anastasia Malek -- Metabolomic profiling of ovarian carcinomas using mass spectrometry / Miranda Y. Fong, Jonathan McDunn, and Sham S. Kakar -- Choline metabolic profiling by magnetic resonance spectroscopy / Egidio Iorio ... [et al.] -- Proteomic Profiling of ovarian cancer models using TMT-LC- MS/MS / John Sinclair and John F. Timms -- Characterization of signalling pathways by reverse phase protein arrays / Katharina Malinowsky ... [et al.] -- N-glycosylation analysis by HPAEC-PAD and mass spectrometry / Sebastian Kandzia and Júlia Costa -- In vivo and in vitro properties of ovarian cancer cells / Anastasia Malek -- Establishment of primary cultures from ovarian tumor tissue and ascites fluid / Brigitte L. Thériault ... [et al.] -- Ovarian cancer stem cells enrichment / Lijuan Yang and Dongmei Lai -- Assessment of resistance to anoikis in ovarian cancer / Xiaoping He, Jeremy Chien, and Viji Shridhar -- Analysis of EMT by flow cytometry and immunohistochemistry / Robert Strauss, Jiri Bartek, and André Lieber -- Challenges in experimental modeling of ovarian cancerogenesis / Jim J. Petrik -- Transformation of the human ovarian surface epithelium with genetically defined elements / Weiwei Shan and Jinsong Liu -- In vitro model of spontaneous mouse OSE transformation / Paul C. Roberts and Eva M. Schmelz -- Orthotopic, syngeneic mouse model to study the effects of epithelial-stromal interaction / James B. Greenaway and Jim J. Petrik -- Immunocompetent mouse model of ovarian cancer for in vivo imaging / Selene Nunez-Cruz and Nathalie Scholler -- Drug delivery approaches for ovarian cancer therapy / Anastasia Malek -- Polymer-based delivery of RNA-based therapeutics in ovarian cancer / Ulrike Weirauch ... [et al.] -- Ligand-coupled lipoprotein for ovarian cancer-specific drug delivery / Ian R. Corbin -- Mesoporous silicon particles for sustained gene Silencing / Nafis Hasan ... [et al.] -- Exosomes as a potential tool for a specific delivery of functional molecules / Irina Nazarenko, Anne-Kathleen Rupp, and Peter Altevogt.
  • 2008From: Springer
    George Coukos, Andrew Berchuck, Robert Ozols, editors.
    Also available: Print – 2008
  • 2016From: Springer
    Gilles Freyer, editor.
    1. Systemic treatment of cancer in the older-aged persons -- 2. Cognitive function during and after treatment in elderly ovarian cancer patients -- 3. Histopathology of ovarian cancers in elderly patients -- 4. Care of the elderly ovarian cancer patient: the surgical challenge -- 5. Chemotherapy: first-line strategy -- 6. Chemotherapy for recurrent ovarian cancer in the elderly patients -- 7. Management of antiangiogenic agents -- 8. How to design clinical trials? -- 9. Biological research: current directions.
  • 2009From: Springer
    edited by M. Sharon Stack, David A. Fishman.
    Also available: Print – 2009
  • 2010From: Springer
    edited by M.A. Hayat.
  • 2016From: Springer
    Gautam N. Allahbadia, Yoshiharu Morimoto, editors.
  • 2014From: CRCnetBASE
    edited by Patricia B. Hoyer, The University of Arizona, College of Medicine, Tucson, USA.
    "Today, we are exposed to an ever-growing number of chemicals in the environment and there is an increasing awareness of the effects of these chemicals on the ovaries. As such, the potential for xenobiotic-induced infertility needs to be better understood. Additionally, menopause-associated disorders are of growing health concern in view of the fact that by the year 2025, 19.5% of the population of the U.S. will be menopause-aged women. Exploring research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles, this book is an essential resource for researchers in academia, regulatory agencies, and industry"--Provided by publisher.
  • edited by Karl Kreder, Roger Dmochowski ; foreword by Paul Abrams.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2012From: Springer
    Alan J. Wein, Christopher Chapple.
    Overactive Bladder in Clinical Practice provides a timely and comprehensive update on the overactive bladder (OAB) syndrome. The symptoms of urgency, with or without urge incontinence, usually with frequency or nocturia, now defined as the overactive bladder syndrome, have become a hot topic in urology, gynecology and urogynecology. Epidemiological data show very high disease prevalence (19%), particularly when compared with other chronic conditions such as diabetes (2%) and asthma (7%). OAB symptoms impact severely on patient's quality of life, causing significant impairment of patient vitality and limiting their physical role, similar to diabetes. The OAB syndrome involves all age groups, both sexes and is frequently found in neurogenic patients. This book will cover all aspects of OAB epidemiology, economics, pathophysiology, conservative, pharmaceutical and surgical and is invaluable reading for residents and trainees in urology, gynecology and urogynecology.
  • 2016From: Springer
    Anna Padoa, Talli Y. Rosenbaum, editors.
    Definitions and Basic Etiology of the Overactive Pelvic Floor -- Overactive Pelvic Floor: Female Sexual Functioning -- The Pelvic Floor and Male Sexual Function -- Female Genital Pain and Penetration Disorders -- Bladder Pain Syndromes/Interstitial Cystitis and the Overactive Pelvic Floor -- Chronic Pelvic Pain Syndromes in Males -- Musculoskeletal Conditions Related to Pelvic Floor Muscle Overactivity -- Female Voiding Dysfunction -- Overactive Pelvic Floor: Gastrointestinal Morbidities -- Subjective Assessment -- Objective Assessment of the Overactive Pelvic Floor -- Electromyography -- Female pelvic floor imaging with emphasis on the overactive pelvic floor -- Urodynamic assessment -- Medical Therapies for the Treatment of Overactive Pelvic Floor -- Treatment Only: A Classical Physical Therapy Approach to an Overactive Pelvic Floor -- An Alternative Physical Therapy Approach to the Overactive Pelvic Floor -- A Tale of Two Pain States- The Integrative Physical Therapy Approach to the Overactive Pelvic Floor -- Complementary and Alternative Therapies for the Overactive Pelvic Floor -- Psychosocial Management.
  • Jessica H. McCoy.
    The "last mile" of a supply chain is the final step of that supply chain before the product reaches the end consumer. In humanitarian and health delivery supply chains, the last mile represents the final leg of the journey for health care or other assistance to reach beneficiaries, and is a critical bottleneck contributing to the acutely inadequate health care access in resource-limited regions. Operations research methodology can be used to evaluate, lessen, and ultimately overcome this bottleneck. In this dissertation, we present four models developed for this context. First, we develop an inventory model to analyze the interaction between a stockpile and a downstream relief operation for large humanitarian organizations such as the United Nations High Commissioner for Refugees. Second, we present an optimization model that explicitly includes treatment adherence when integrating a clinic's capacity decisions with population health outcomes. Our final two models investigate the effectiveness, then the efficiency and equity, of fleet management programs for health worker vehicles (e.g., nonprofit Riders for Health) in places like rural sub-Saharan Africa. Health access challenges are fundamentally supply chain problems, and these models are a first step in using operations research tools to improve health delivery in resource-limited regions. Humanitarian organizations must use their financial resources wisely to carry out their mandates, and models such as these can help organizations make the best use of their limited response resources.
  • Namrata K. Uberoi, Annie L. Mach, and Bernadette Fernandez.
    The Patient Protection and Affordable Care Act (ACA; P.L. 111-148, as amended) requires health insurance exchanges to be established in every state. Exchanges are marketplaces where individuals and small businesses can shop for and purchase private health insurance coverage. States must have two types of exchanges: an individual exchange and a small business health options program (SHOP) exchange. Exchanges may be established either by the state itself as a state-based exchange (SBE) or by the Secretary of Health and Human Services (HHS) as a federally-facilitated exchange (FFE). In states with FFEs, the exchange may be operated solely by the federal government or in conjunction with the state. Persons who obtain coverage through the individual exchange may be eligible for financial assistance from the federal government. The financial assistance in the individual exchanges is available in two forms: premium tax credits and cost-sharing subsidies. Small businesses that use the SHOP exchange may be eligible for small business health insurance tax credits. The tax credits assist small businesses with the cost of providing health insurance coverage to employees. The ACA generally requires that health insurance plans offered through an exchange are Qualified Health Plans (QHPs). Typically in order to be a certified as a QHP, a plan must offer the essential health benefits, comply with cost-sharing limits, and meet certain market reforms. Exchanges may also offer other types of health insurance plans such as catastrophic and dental-only plans. This report provides an overview of the various components of the health insurance exchanges. The report includes summary information about how exchanges are structured, the intended consumers for health insurance exchange plans, and consumer assistance available in the exchanges, as specified in the ACA. The report also describes the availability of financial assistance for certain exchange consumers and small businesses and outlines the range of plans offered through exchanges. Moreover, the report provides a brief summary of the implementation and operation of exchanges since 2014.
  • 2006From: Springer
    edited by George A. Bray, Donna H. Ryan.
  • 2014From: Springer
    Roy Homburg.
    The second edition of this highly successful book updates the reader on progress and developments in the field of ovulation induction and controlled ovarian stimulation. Furthermore, it provides the busy clinician with a reliable overview of the principles involved and the management needed. As with the previous edition, the emphasis throughout this book is on logical evidence and evidence-based solutions, supplemented with Professor Roy Homburgs extensive clinical experience gleaned from more than forty years working in the field. A number of highly useful algorithms and explanatory tables reinforce this approach, ensuring that the reader is presented with easy-to-grasp, well-presented information that maximizes clarity and understanding. Ovulation Induction and Controlled Ovarian Stimulation: A Practical Guide offers a concise, no-nonsense, practical guide to ovulation induction and controlled ovarian stimulation and will be an essential resource for general gynaecologists, fertility specialists and trainees, health workers and students.
  • 2015From: Springer
    Jean-Claude Emperaire ; foreword by Bruno Lunenfeld.
  • 2016From: Oxford Medicine Online
    Dr. Sanja Thompson, Dr. Nicolsa Lovett, Professor John Grimley Evans, Professor Sarah Pendlebury.
    Based around the specialist training curriculum for geriatrics, this volume covers the presentation, management, and treatment of illness in older people and relevant social and ethical issues.
  • From: OxfordTRIAL ENDS June 30, 2017
    "Oxford Clinical Psychology provides full-text access to over 300 titles in Oxford's global clinical psychology publishing program in an integrated online service. Covering a broad range of specialty areas, disorders, and treatment modalities, Oxford Clinical Psychology enables users to search and browse high-quality research and practice information."--Website.
  • 2016From: Oxford Medicine Online
    edited by Richard Leach, Derek Bell, Kevin Moore.
  • 2006From: MyiLibrary
    Managing editor, R. Cammack ; General editors, T.K. Attwood ... [et al.].
    Also available: Print – 2006
  • edited by H.C.G. Matthew and Brian Harrison.
  • A complete text of the 2nd. ed. of the Oxford English dictionary with quarterly updates, including revisions not available in any other form.
  • edited by Greg McLatchie, Neil Borley, Joanna Chikwe.
    PrintStatus: Not Checked OutLane Catalog Record
    Good surgical practice -- Principles of surgery -- Surgical pathology -- Practical procedures -- Head and neck surgery -- Breast and endocrine surgery -- Upper gastrointestinal surgery -- Liver, pancreatic, and biliary surgery -- Abdominal wall -- Urology -- Colorectal surgery -- Paediatric surgery -- Major trauma -- Orthopaedic surgery -- Plastic surgery -- Cardiothoracic surgery -- Peripheral vascular disease -- Transplantation -- Surgery in tropical diseases -- Eponymous terms and rarities.
  • 2016From: Oxford Medicine Online
    Heather Baid, Fiona Creed, and Jessica Hargreaves.
    A practical, concise, easily accessible and evidence-based guide for all levels of nursing staff working in critical care environments.
  • 2017From: Oxford Medicine Online
    edited by Robert Crouch, Alan Charters, Mary Dawood, and Paula Bennett.
    General principles of emergency nursing -- First principles -- Investigations -- Emergency care of the infant and child -- Obstetric emergencies -- Neurological emergencies -- Respiratory emergencies -- Cardiovascular emergencies -- Musculoskeletal injuries -- Gastrointestinal emergencies -- Genitourinary emergencies -- Skin emergencies -- Ophthalmological emergencies -- ENT emergencies -- Major trauma -- Endocrine and metabolic emergencies -- Haematological emergencies -- Overdose and poisoning -- Mental health emergencies -- Emergencies in older patients -- Skills reminder.
  • edited by Michael R. Nash, Amanda J. Barnier.
    PrintStatus: Not Checked OutLane Catalog Record
  • 2016From: Oxford Medicine Online
    Mark Radford, Maria Kisiel, Alison Smith, editors.
    1. Introduction to the surgical patient -- 2. Managing the surgical ward -- 3. Surgical Care models -- 4. Pre-operative assessment and preparation -- 5. Pre-operative optimization -- 6. Transfer to other departments or theatre -- 7. Intraoperative care -- 8. Ward post-operative care -- 9. Pain management -- 10. Nutrition and hydration -- 11. Transfusion of blood products -- 12. Wound care -- 13. Skin assessment -- 14. Infection: prevention, control, and treatment -- 15. Post-operative complications -- 16. Surgical Nursing Procedures -- 17. Opthalmology -- 18. Upper gastrointestinal and hepatobiliary surgery -- 19. Colorectal and lower gastrointestinal surgery -- 20. Trauma and orthopaedics -- 21. Vascular surgery -- 22. Urology and renal -- 23. Neurological and spinal surgery -- 24. Burns and plastic surgery -- 25. Thoracic surgery -- 26. Cardiac surgery -- 27. Breast surgery -- 28. Gynaecological surgery.
  • 2008From: Ovid
    Michael Eddleston ... [et al.], editors.
  • Includes all of words, phrases, and translations, in French, German, Spanish and Italian from the print dictionaries. Users can search the full A-Z from both sides of the dictionary in Oxford's unabridged bilingual dictionaries: French, German, Spanish, and Italian.
  • 2010<Updated Feb. 2016>From: Oxford Medicine Online
    edited by David A. Warrell, Timothy M. Cox, John D. Firth ; sub-editor immunological mechanisms and disorders of the skin, Graham S. Ogg.
    v. 1. -- section 1. On being a patient -- section 2. Modern medicine: foundations, achievements, and limitations -- section 3. Global patterns of disease and medical practice -- section 4. Cell biology -- section 5. Immunological mechanisms -- section 6. Principles of clinical oncology -- section 7. Infection -- section 8. Sexually transmitted diseases and sexual health -- section 9. Chemical and physical injuries and environmental factors and disease -- section 10. Clinical pharmacology -- section 11. Nutrition -- section 12. Metabolic disorders -- v. 2. -- section 13. Endocrine disorders -- section 14. Medical disorders in pregnancy -- section 15. Gastroenterological disorders -- section 16. Cardiovascular disorders -- section 17. Critical care medicine -- section 18. Respiratory disorders -- section 19. Rheumatological disorders -- v. 3. -- section 20. Disorders of the skeleton -- section 21. Disorders of the kidney and urinary tract -- section 22. Disorders of the blood -- section 23. Disorders of the skin -- section 24. Neurological disorders -- section 25. The eye -- section 26. Psychiatry and drug related problems -- section 27. Forensic medicine -- section 28. Sports medicine -- section 29. Geratology -- section 30. Pain -- section 31. Palliative medicine -- section 32. Biochemistry in medicine -- section 33. Acute medicine.
    Also available: Print – v. 1-3, 2010.
  • edited by Betty R. Ferrell, RN, PhD, MA, FAAN, FPCN, CHPN, Professor and Director, Department of Nursing Research and Education, City of Hope Comprehensive Cancer Center, Duarte, California, Nessa Coyle, ACHPN, PhD, FAAN, Consultant, Palliative Care and Clinical Ethics in Oncology, New York, New York, Judith A. Paice, PhD, RN, FAAN, Director of Cancer Pain Program, Division of Hematology-Oncology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
    Preface -- Acknowledgments -- Contributors -- SECTION I: GENERAL PRINCIPLES: Introduction to palliative nursing care / Nessa Coyle -- National consensus project for quality palliative care: promoting excellence in palliative nursing / Constance M. Dahlin -- Hospital-based palliative care / Patricia Maani-Fogelman and Marie A. Bakitas -- Principles of patient and family assessment / John D. Chovan, Douglas Cluxton and Patrice Rancour -- Communication in palliative care: an essential competency for nurses / Constance M. Dahlin and Elaine Wittenberg -- SECTION II: SYMPTOM ASSESSMENT AND MANAGEMENT: Pain assessment / Regina M. Fink, Rose A. Gates, and Robert K. Montgomery -- Pain at the end of life / Judith A. Paice -- Fatigue / Edith O'Neil-Page, Paula R. Anderson, and Grace E. Dean -- Anorexia and Cachexia / Dorothy Wholihan -- Nausea and vomiting / Kimberly Chow, Daniel Cogan and Sonni Mun -- Dysphagia, xerostomia, and hiccups / Constance M. Dahlin and Audrey Kurash Cohen -- Bowel management: constipation, diarrhea, obstruction, and ascites / Denice Caraccia Economou -- Artificial nutrition and hydration / Michelle S. Gabriel and Jennifer A. Tschanz -- Dyspnea terminal secretions, and cough / Deborah Dudgeon -- Urinary tract disorders / Mikel Gray and Terran Sims -- Lymphedema management / Mei R. Fu and Bonnie B. Lasinski -- Skin disorders: pressure ulcers: prevention and management / Barbara M. Bates-Jensen and Sirin Petch -- Skin disorders: malignant wounds, fistulas, and stomas / Susie Seaman and Barbara M. Bates-Jensen -- Pruritis, fever, and sweats / Philip J. Larkin -- Neurological disorders / Margaret A. Schwartz -- Anxiety and depression / Jeannie V. Pasacreta, Pamela A. Minarik, Leslie Nield-Anderson and Judith A. Paice -- Delirium, confusion, agitation, and restlessness / Debra E. Heidrich and Nancy K. English -- Insomnia / Laura Bourdeanu, Marjorie J. Hein, and Ellen A. Liu -- Sexuality / Marianne Matzo -- Urgent syndromes at the end of life / Barton T. Bobb -- Sedation for refractory symptoms / Patti Knight, Laura A. Espinosa, and Bonnie Freeman -- Complementary and alternative therapies in palliative care / Kate Kravits -- Withdrawal of life-sustaining therapies: mechanical ventilation, dialysis, and cardiac devices / Margaret L. Campbell and Linda M. Gorman -- SECTION III: PSYCHOSOCIAL SUPPORT: The meaning of hope in the dying / Valerie T. Cotter and Anessa M. Foxwell -- Bereavement / Inge B.Corless -- Supporting families in palliative care / Rose Steele and Betty Davies -- Planning for the actual death / Patricia Berry and Julie Griffie -- Spiritual assessment / Elizabeth Johnston Taylor -- Spiritual care intervention / Rev. Pamela Baird -- Meaning in illness / Tami Borneman and Katherine Brown-Saltzman -- SECTION IV: SPECIAL PATIENT POPULATIONS: Caring for those with chronic illness / Terri L. Maxwell -- Cultural considerations in palliative care / Polly Mazanec and Joan T. Panke -- Elderly patients / Susan Derby, Roma Tickoo, and Reggie-Saldivar -- Poor, homeless, and underserved populations / Anne Hughes -- End-of-life care for patients with mental illness and personality disorders / Betty D. Morgan -- Patients with acquired immunodeficiency syndrome / Carl A. Kirton and Deborah Witt Sherman -- Caring for the patient with substance use disorder at the end of life / Kenneth L. Kirsh, Peggy Compton, Kathy Egan-City, and Steven D. Passik -- Palliative care of cancer survivors / Mary S. McCabe and Stacie Corcoran -- Veterans / Deborah Grassman -- SECTION V: END-OF-LIFE CARE ACROSS SETTINGS: Improving the quality of care across all settings / Marilyn Bookbinder and Romina Arceo -- Long-term care: focus on nursing homes / Joan G. Carpenter and Mary Ersek -- Home care and hospice home care / Paula Milone-Nuzzo, Elizabeth Ercolano, and Ruth McCorkle -- The intensive care unit / Jennifer McAdam and Kathleen Puntillo -- Palliative care nursing in the outpatient setting / Pamela Stitzlein Davies -- Rehabilitation and palliative care / Donna J. Wilson and Kathleen Michael -- The emergency department / Mary Bowman -- The role of nursing in caring for patients undergoing palliative surgery for advanced disease / Anna Cathy Williams, Betty R. Ferrell, Gloria Juarez, and Tami Borneman -- Palliative chemotherapy and clinical trials in advanced cancer: the nurse's role / Virginia Sun -- Rural palliative care / Marie A. Bakitas, Kathleen N. Clifford, J. Nicholas Dionne-Odom, and Elizabeth Kvale -- Palliative care in mass casualty events with scarce resources / Anne Wilkinson and Marianne Matzo -- SECTION VI: PEDIATRIC PALLIATIVE CARE: Symptom management in pediatric palliative care / Melody Brown-Hellsten and Stacey Berg -- Pediatric hospice and palliative care / Vanessa Battista and Gwenn LaRagione -- Pediatric care: transitioning goals of care in the emergency department, intensive care unit, and in between / Barbara Jones, Marcia Levetown and Melody Brown Hellsten -- End-of-life decision-making in pediatric oncology / Pamela S. Hinds, Linda L. Oakes, and Wayne L. Furman -- Palliative care in the neonatal intensive care unit / Cheryl Thaxton, Brigit Carter, and Chi Dang Hornik -- Grief and bereavement in pediatric palliative care / Rana Limbo and Betty Davies -- Pediatric pain: knowing the child before you / Mary Layman-Goldstein and Dane Kramer -- SECTION VII: SPECIAL ISSUES FOR THE NURSE IN END-OF-LIFE CARE: The advanced practice registered nurse / Clareen Wiencek -- Reflections on occupational stress in palliative care nursing: is it changing? / Mary L.S. Vachon, Peter K. Huggard, and Jayne Huggard -- Ethical considerations in palliative care / Maryjo Prince-Paul and Barbara J. Daly -- Palliative care and requests for assistance in dying / Deborah L. Volker -- Nursing education / Pamela Malloy -- Nursing research / Betty R. Ferrell, Marcia Grant, and Virginia Sun -- Enhancing team effectiveness / Shirley Otis-Green and Iris Cohen Fineberg -- Clinical intervention, economic impact, and palliative care / Patrick L. Coyne, Thomas J. Smith, and Laurel J. Lyckholm -- International palliative care initiatives / Stephen R. Connor -- Palliative care in Canada / Doris Howell and Ann Syme -- Palliative care in Australia and New Zealand / Margaret O'Connor -- Palliative care in the UK / Nancy Preston and Katherine Froggatt -- Palliative care in Europe / Marianne Jensen Hjermstad and Stein Kaasa -- Palliative care in Latin America / Tania Pastrana, Denisse Ruth Parra Giordano, Miguel Antonio Sánchez Cárdenas, Xiomara Carmona Montoya, and Beatriz Montes de Oca -- Palliative care in Africa / Faith N. Mwangi-Powell, Julia Downing, Richard A. Powell, Fatia Kiyange, and Henry Ddungu -- Palliative care in Japan / Sayaka Takenouchi and Keiko Tamura -- Palliative care in South Korea / Hyun Sook Kim and Boon Han Kim -- Palliative care in Eastern Europe / Nicoleta Mitrea and Daniela Mosoiu -- Palliative care in the Philippines / Ayda G. Nambayan and Henry U. Lu -- Palliative care in situations of conflict / Nathan I. Cherny -- Palliative care as a human right / Frank Brennan, Liz Gwyther, Diederik Lohman, Fatia Kiyange, Tamar Ezer, and Faith N. Mwangi-Powell -- A good death / Gay Walker -- APPENDIX: Palliative care resource list / Rose Virani and Licet Garcia.
  • edited by Paul H. Blaney & Theodore Millon.
    PrintStatus: Not Checked OutLane Catalog Record
    Part I: Foundations -- A brief history of psychopathology / Theodore Millon -- Classification / Roger K. Blashfield, Jared W. Keeley, and Danny R. Burgess -- Developmental pathogenesis / Theodore Millon -- Studying psychopathology / Michael L. Raulin and Scott O. Lilienfeld -- Part II: Major Axis I syndromes -- Anxiety disorders: panic and phobias / Steven Taylor, Brian J. Cox, and Gordon J. G. Asmundson -- Generalized anxiety disorder and obsessive-compulsive disorder / Timothy A. Brown and Amy E. Lawrence -- Posttraumatic stress disorder / Richard J. McNally -- Mood disorders: biological bases / Sheri L. Johnson ... [et al.] -- Depression: social and cognitive aspects / Rick E. Ingram, Walter D. Scott, and Sarah Hamill -- Substance abuse: etiological considerations / Robert O. Pihl -- Substance abuse: diagnosis, comorbidity, and psychopathology / Susan R. Tate, Michelle L. Drapkin, and Sandra A. Brown -- Schizophrenia: etiology and neurocognition / Barbara A. Cornblatt ... [et al.] -- Schizophrenia: interpersonal functioning / Jill M. Hooley -- Paranoid and delusional disorders / Paul H. Blaney -- Part III: Other Axis I syndromes -- Sexual dysfunctions / Donald S. Strassberg and Michael A. Perelman -- Eating disorders / Howard Steiger and Kenneth R. Bruce -- Dissociative disorders / Onno van der Hart and Ellert R. S. Nijenhuis -- Somatoform disorders / Theo K. Bouman and Georg H. Eifert -- Sleep/wake disorders / Charles M. Morin and Jack D. Edinger -- Sexual disorders / James M. Cantor, Roy Blanchard, and Howard Barbaree -- Part IV: Axis II disorders -- Personality and its disorders: structural models, mathematical methods, and theoretical conceptions / Theodore Millon -- Schizoid and avoidant personality disorders / David P. Bernstein, Arnoud Arntz, and Laura Travaglini -- Dependent and histrionic personality disorders / Robert F. Bornstein and Iris L. Malka -- Psychopathy / Robert D. Hare and Craig S. Neumann -- Sadistic personality disorder / Michael H. Stone, Jeremy R. Butler, and Kathleen M. Young -- Obsessive-compulsive and negativistic personality disorders / Joseph T. McCann -- Schizotypic psychopathology: theory, evidence, and future directions / Mark F. Lenzenweger -- Borderline personality disorder / Joel Paris -- Depressive personality disorder / Daniel N. Klein and Melissa L. Bessaha -- Narcissistic personality disorder / Elsa Ronningstam.
  • 2001From: Karger
    volume editors, Jens Thiele, Peter Elsner.
    Also available: Print – 2001
  • pt. A-B, 1999.From: ScienceDirect
    pt. BFrom: ScienceDirect
    edited by Lester Packer.
    Also available: Print – pt. A-B, 1999.
  • 2008From: Springer
    Giuseppe Valacchi, editor ; Paul A. Davis, co-editor.
  • 2008From: Springer
    John C. Stavridis.
  • 1967From: ScienceDirect
    edited by Ronald W. Estabrook and Maynard E. Pullman.
    Also available: Print – 1967
  • 2007From: Springer
    [edited by] Mark D. Evans, Marcus S. Cooke.
    Oxidatively generated damage to cellular DNA : mechanistic aspects / Jean Cadet ... [et al.] -- Chlorination and nitration of DNA and nucleic acid components / Clare L. Hawkins ... [et al.] -- Prevention of the mutagenicity and cytotoxicity of oxidized purine nucleotides / Yusaku Nakabeppu ... [et al.] -- Nucleotide incision repair : an alternative and ubiquitous pathway to handle oxidative DNA damage / Sophie Couvé-Privat ... [et al.] -- OGG1 : from structural analysis to the knockout mouse / Arne Klungland, Jon K. Laerdahl, and Torbjörn Rognes -- Processing of 3'-end modified DNA strand breaks induced by oxidative damage / Jason L. Parsons, Emma Boswell, and Grigory L. Dianov -- Oxidative damage and promoter function / David Mitchell and Rita Ghosh -- Oxidative DNA damage and telomere shortening / Torsten Richter and Thomas von Zglinicki -- Oxidative damage and repair in the mitochondrial genome / Lene Juel Rasmussen and Keshav K. Singh -- The role of oxidative damage to nucleic acids in the pathogenesis of neurological disease / V. Prakash Reddy ... [et al.] -- Nucleic acid oxidation and the pathogenesis of cardiovascular diseases / Maria Grazia Andreassi -- Oxidative DNA damage and carcinogenesis / Ryszard Olinski, Marek Foksinski, and Barbara Tudek -- The physiological and pathological roles of oxidative damage to DNA in relation to life stage / Alberto Izzotti -- Analysis of 8-hydroxy-2'-deoxyguanosine as a marker of oxidatively damaged DNA in relation to carcinogenesis and aging / H. Kasai ... [et al.] -- Oxidatively damaged DNA and inflammation / Peter C. Dedon and Marita C. Barth -- The role of antioxidants in the prevention of oxidative damage to nucleic acids / Peter Muller and Steffen Loft.
  • edited by Johannes Buchner, Luis Moroder.
  • 2009From: Springer
    Sigrid C. Veasey, editor.
  • 2006From: CRCnetBASE
    edited by Yuan Luo, Lester Packer.
  • 2015From: Springer
    edited by Mieczyslaw Pokorski.
    Cardiorespiratory function is prominently affected by oxidative stress. Cigarette smoking is the archetype of oxidative and nitrative stress and free radical formation. New adverse effects of smoking keep on ppopping up in research. The chapters provide the comprehensive view of new developments in this area regarding cardiovascular and lung function and muscle catabolism. Alterations in inflammatory cytokines and proteins as well as degradation of muscle proteins due to smoking, by far unrecognized, caused by oxidative stress also are presented. Much less is known about the effect of cognitive stress on vagally-mediated cardiorespiratory function and surprisingly, on vagal immune pathway. The experimental studies also show that clinically important meconium aspiration syndrome contains an oxidative trait which is amenable to antioxidative treatment. This volume creates a source of information on the damaging role of oxidative stress in cardiorespiratory function that has by far not been available.
    Also available: Print – 2015
  • Cadenas, Enrique; Packer, Lester.
    Also available: Print – v. 15, 2005.
  • 2011From: Springer
    Natan Gadoth, Hans Hilmar Göebel, editors.
    Chapter 1: The Role of Free Radicals in the Nervous System -- Chapter 2: Why Is the Nervous System Vulnerable to Oxidative Stress? -- Chapter 3: Perinatal Hypoxic-Ischemic Neural Injury and Free Radical Injury: A Fine Balance -- Chapter 4: Oxidative Stress in Neonatal Hypoxic-Ischemic Encephalopathy -- Chapter 5: Oxidative Stress in Multiple Sclerosis Pathology and Therapeutic Potential of Nrf2 Activation -- Chapter 6: Free Radicals in Central Nervous System Inflammation.
  • 2014From: Springer
    Jordi Camps, editor.
    Introduction: Oxidation and inflammation, a molecular link between non-communicable diseases -- Oxidative stress and DNA damage in obesity-related tumorigenesis -- High density lipoproteins and ischemia reperfusion injury: the therapeutic potential of HDL to modulate cell survival pathways -- The DING family of phosphate binding proteins in inflammatory diseases -- Inflammation, infection, cancer and all that...the role of paraoxonases -- Autophagy is an inflammation-related defensive mechanism against disease -- Delta-5 and delta-6 desaturases: crucial enzymes in polyunsaturated fatty acid-related pathways with pleiotropic influences in health and disease -- Systemic inflammation, intestine and paraoxonase-1 -- Serotonin modulation of macrophage polarization: inflammation and beyond -- Energy metabolism and metabolic sensors in stem cells: the metabostem crossroads of aging and cancer -- Molecular promiscuity of plant polyphenols in the management of age-related diseases: far beyond their antioxidant properties -- Postprandial inflammation: targeting glucose and lipids -- Dynamic interplay between metabolic syndrome and immunity -- The axis AGE-RAGE-soluble RAGE and oxidative stress in chronic kidney disease -- The chemokine (C-C motif) ligand 2 in neuroinflammation and neurodegeneration.
    Also available: Print – 2014
  • 2013From: Springer Protocols
    edited by Donald Armstrong, Dhruba J. Bharali.
    Nanoscale biosensor for detection of reactive oxygen species / Tarl W. Prow, Daniel Sundh, and Gerard A. Lutty -- Nanoparticles : toxicity, radicals, electron transfer, and antioxidants / Peter Kovacic and Ratnasamy Somanathan -- Encapsulation of antioxidants in gastrointestinal-resistant nanoparticulate carriers / Eliana B. Souto ... [et al.] -- Toxicity of novel nanosized rormulations used in medicine / Afaf El-Ansary ... [e tal.] -- Fullerenol nanoparticles : toxicity and antioxidant activity / Rade Injac, Matevz Prijatelj, and Borut Strukelj -- Hydrogen peroxide (H2O2) detection with nanoprobes for biological applications : a mini-review / Gwangseong Kim, Yong-Eun Koo Lee, and Raoul Kopelman -- Studying the oxidative stress paradigm in vitro : a theoretical and practical perspective / Martin J.D. Clift and Barbara Rothen-Rutishauser -- Evaluation of the effect of acute and subacute exposure to TiO2 nanoparticles on oxidative stress / Shichang Liu and Zhuo Yang -- Biomedical applications of nano-antioxidant / Geeta Watal ... [et al.] -- Lipid peroxidation due to in vitro and in vivo exposure of biological samples to nanoparticles / Anca Dinischiotu ... [et al.] -- Testing nanomaterial toxicity in unicellular eukaryotic algae and fish cell lines / Alexandra Kroll, Dana Kühnel, and Kristin Schirmer -- Gold nanoparticles and oxidative stress in the blue mussel, mytilus edulis / Sara Tedesco ... [et al.] -- Oxidative biomarkers to assess the nanoparticle-induced oxidative stress / Rama Narsimha Reddy Anreddy, Narsimha Reddy Yellu, and Krishna R. Devarakonda -- Vesicular antioxidants : role in age-related cerebral oxidative injury / Sibani Sarkar, Ardhendu Kumar Mandal, and Nirmalendu Das -- Methods for detection of oxidative stress and genotoxicity of engineered nanoparticles / Ashutosh Kumar, Vyom Sharma, and Alok Dhawan -- Size-dependent study of pulmonary responses to nano- sized iron and copper oxide nanoparticles / Rajiv Kumar and Dattatri K. Nagesha -- In vitro techniques to investigate the oxidative effects of quantum dots / Ridhima Juneja and Indrajit Roy -- Hybrid polymeric nanoparticles : potential candidate for ophthalmic delivery / Dhruba J. Bharali, Donald Armstrong, and Shaker A. Mousa -- Relevance of nanotechnology in modulating oxidative stress : an overview / Dhruba J. Bharali and Shaker A. Mousa.
  • 2006From: Springer
    H. Parvez, P. Riederer (eds.).
  • 2013From: Springer
    Ursula Jakob, Dana Reichmann, editors.
    Many physiological conditions such as host defense or aging and pathological conditions such as neurodegenerative diseases, and diabetes are associated with the accumulation of high levels of reactive oxygen species and reactive nitrogen species. This generates a condition called oxidative stress. Low levels of reactive oxygen species, however, which are continuously produced during aerobic metabolism, function as important signaling molecules, setting the metabolic pace of cells and regulating processes ranging from gene expression to apoptosis. For this book we would like to recruit the experts in the field of redox chemistry, bioinformatics and proteomics, redox signaling and oxidative stress biology to discuss how organisms achieve the appropriate redox balance, the mechanisms that lead to oxidative stress conditions and the physiological consequences that contribute to aging and disease.
  • 2008From: Springer
    edited by Satomi Miwa, Kenneth B. Beckman, Florian L. Muller.
  • 2012From: Springer
    Douglas R. Spitz, Kenneth J. Dornfeld, Koyamangalath Krishnan, David Guis, editors.
    This volume details how oxidative stress in cancer biology can be utilized to more effectively design interventions to enhance therapeutic responses while causing fewer treatment limiting complications.
  • 2012From: Wiley
    edited by Tahira Farooqui, Akhlaq A. Farooqui.
  • 2009From: Springer
    edited by Raquel Soares and Carla Costa.
  • 2007From: ScienceDirect
    edited by Helmut Sies and Bernard Brüne.
    Also available: Print – 2007
  • 1984From: ScienceDirect
    edited by Lester Packer.
    Also available: Print – 1984
  • 1990From: ScienceDirect
    edited by Lester Packer, Alexander N. Glazer.
    Also available: Print – 1990
  • 1994From: ScienceDirect
    edited by Lester Packer.
    Also available: Print – 1994
  • 1994From: ScienceDirect
    edited by Lester Packer.
    Also available: Print – 1994
  • 2016From: WHO
    Also available: Print – 2016
  • Kyung A. Kang, David K. Harrison, Duane F. Bruley, editors.
  • 2005From: Springer
    edited by Paul Okunieff, Jacqueline Williams, Yuhchyau Chen.
    Also available: Print – 2005
  • 2006From: Springer
    edited by Giuseppe Cicco... [et al.].
    Also available: Print – 2006
  • 2007From: Springer
    David J. Maguire, Duane F. Bruley, David K. Harrison (eds.).
    Also available: Print – 2007
  • 2009From: Springer
    Per Liss, Peter Hansell, Duane F. Bruley, David K. Harrison, editors.
    Air and fire : Carl Wilhelm Scheele, Torbern Bergman, the Royal Society of Sciences and the discovery of oxygen in Uppsala in 1772 / Lars-Olof Sundelöf -- Mathematical modeling of the interactiion betwen oxygen, nitric oxide and superoxide / Donald G. Buerk -- Haemoglobin saturation controls the red blood cell mediated hypoxic vasorelaxation / Andrew G. Pinder ... [et al.] -- Blood vessel specific vaso-activity to nitrite under normoxic and hypoxic conditions / Thomas E. Ingram ... [et al.] -- Nitrite-induced improved blood circulation associated with an increase in a pool of RBN-NO with NO bioactivity / Joseph M. Rifkind ... [et al.] -- The control of oxidative phosphorylation in the adrenal gland (Y1) cell line / James E.J. Murphy and Richard K. Porter -- Replication of murine mitochondrial DNA following irradiation / Hengshan Zhang ... [et al.] -- Effects of anesthesia on brain mitochondrial function, blood flow, ionic and electrical activity monitored in vivo / Nava Dekel ... [et al.] -- The influence of flow redistribution on working rat muscle oxygenation / Louis Hoofd and Hans Degens -- Heterogeneity of capillary spacing in the hypertrophied plantaris muscle from young-adult and old rats / Hans Degens, Christopher I. Morse, and Maria T.E. Hopman -- Microvascularity of the lumbar erector spinae muscle during sustained prone trunk extension test / Rammohan V. Maikala and Yagesh N. Bhambhani -- Fiber capillary supply related to fiber size and oxidative capacity in human and rat skeletal muscle / Rob C.I. Wüst, Sarah L. Gibbings, and Hans Degens -- Novel therapeutic approach targeting the HIF-HRE system in the kidney / Masaomi Nangaku -- Carotid body sensory discharge and glomus cell HIF-1[alpha] are regulated by a common oxygen sensor / S. Lahiri ... [et al.] -- Impact of reactive oxygen species on the expression of adhesion molecules in vivo / Oliver Thews ... [et al.] -- Mini sensing chip for point-of-care acute myocardial infarction diagnosis utilizing micro-electro-mechanical system and nano-technology / Jianting Wang ... [et al.] -- A chemical biosynthesis design for an antiatherosclerosis drug by acyclic tocopherol intermediate analogue based on "isoprenomics" / Yoshihiro Uto ... [et al.] -- Zymogen protein C concentrate for safer heterozygote surgery, "I am a guinea pig!" / Duane F. Bruley -- Steady state redox levels in cytochrome oxidase : relevance for in vivo near infrared spectroscopy (NIRS) / Chris E. Cooper ... [et al.] -- Bicuculline-induced seizures : a challenge for optical and biochemical modeling of the cytochrome oxidase CUa NIRS signal / Chris E. Cooper ... [et al.] -- A method to calculate arterial and venous saturation from near infrared spectroscopy (NIRS) / Jan Menssen ... [et al.] -- Development of a dynamic test phantom for optical topography / Peck H. Koh, Clare E. Elwell, and David T. Delpy -- Numerical simulation of oxygen transport in cerebral tissue / Toshihiro Kondo ... [et al.] -- Non-invasive estimation of metabolic flux and blood flow in working muscle : effect of blood-tissue distribution / Nicola Lai ... [et al.] -- Oxygen extraction index measured by near infrared spectroscopy : a parameter for monitoring tissue oxygenation? / Oskar Baenziger ... [et al.] -- Non-invasive measurement of the superficial cortical oxygen partial pressure / Chris Woertgen ... [et al.] -- One sensor fits all : a new approach in monitoring brain physiology / H. Doll ... [et al.] -- Evaluation of NIRS data based on theoretical analysis of oxygen transport to cerebral tissue / Kazunori Oyama ... [et al.] -- Myocardial capillary net and blood constituents in streptozotocin (STZ-)-induced diabetic rats / Tomiyasu Koyama and Akira Taka -- Effects of proinsulin C-peptide on oxygen transport uptake and utilization in insulinopenic diabetic subjects : a review / Lina Nordquist and Sara Stridh -- Reduced oxygenation in diabetic rat kidneys measured by T2* weighted magnetic resonance micro-imaging / Jenny Edlund ... [et al.] -- Identification and distribution of uncoupling protein isoforms in the normal and diabetic rat kidney / Malou Friederich ... [et al.] -- Iodinated contrast media decrease renomedullary blood flow : a possible cause of contrast media-induced nephropathy / Per Liss ... [et al.] -- C-peptide normalizes glomerular filtration rate in hyperfiltrating conscious diabetic rats / Sara Stridh ... [et al.] -- Lipoprotein nanoplatform for targeted delivery of diagnostic and therapeutic agents / Jerry D. Glickson ... [et al.] -- Prognostic potential of the pre-therapeutic tumor oxygenation status / Peter Vaupel -- Histological basis of MR/optical imaging of human melanoma mouse xenografts spanning a range of metastatic potentials / He N. Xu ... [et al.] -- The relationship between vascular oxygen distribution and tissue oxygenation / Alexandru Daşu and Iuliana Toma-Daşu -- Intraoperative measurement of colonic oxygenation during bowel resection / Daya B. Singh ... [et al.] -- Quantifying tumour hypoxia by PET imaging : a theoretical analysis / Iuliana Toma-Daşu, Alexandru Da̧su, and Anders Brahme -- New measurements for assessment of impaired cerebral autoregulation using near-infrared spectroscopy / Dominique De Smet ... [et al.] -- Single shot T1p magnetic resonance imaging of metabolically generated water in vivo / Eric A. Mellon ... [et al.] -- Brain tissue oxygen consumption and supply induced by neural activation : determined under suppressed hemodynamic response conditions in the anesthetized rat cerebral cortex / Kazuto Masamoto ... [et al.] -- Brain oxygen balance under various experimental pathophysiological conditions / Michal Schechter, Judith Sonn, and Avraham Mayevsky -- Ketones suppress brain glucose consumption / Joseph C. LaManna ... [et al.] -- False positives in functional near-infrared topography / Ilias Tachtsidis ... [et al.] -- Relationship between brain tissue haemodynamics, oxygenation, and metabolism in the healthy human adult brain during hyperoxia and hypercapnea / Ilias Tachtsidis ... [et al.] -- Use of a Codman microsensor intracranial pressure probe : effects on near infrared spectroscopy measurements and cerebral hemodynamics in rats / Helga Blockx, Willem Flameng, and Geofrey De Visscher -- Effect of severe hypoxia on prefrontal cortex and muscle oxygenation responses at rest and during exhaustive exercise / Thomas Rupp and Stéphane Perrey.
    Also available: Print – 2009
  • 2010From: Springer
    Duane F. Bruley, Eiji Takahashi, editors.
    Part 1. Physiology and pathophysiology of O2 transport -- Part 2. In vivo measurement of O2 -- Part 3. Exercise and O2 transport -- Part 4. O2 microenvironment in cancer -- Part 5. Clinical aspects of O2 transport.
    Also available: Print – 2010
  • 2011From: Springer
    Joseph C. LaManna ... [et al.], editors.
    Also available: Print – 2011
  • 2012From: Springer
    Martin Wolf ... [et al.], editors.
    Also available: Print – 2012
  • 2013From: Springer
    William J. Welch ... [et al.], editors.
    Also available: Print – 2013
  • 2013From: Springer
    Sabine Van Huffel, Gunnar Naulaers, Alexander Caicedo, Duane F. Bruley, David K. Harrison, editors.
    Part 1. Hypoxia -- Increased kidney metabolism as a pathway to kidney tissue hypoxia and damage: effects of triiodothyronine and dinitrophenol in normoglycemic rats -- Hypoxia-induced cerebral angiogenesis in mouse cortex with two-photon microscopy -- Reduction of cytochrome c oxidase during vasovagal hypoxia-ischaemia in human adult brain: a case study -- Increased HIF-1[alpha] and HIF-2[alpha] accumulation, but decreased microvascular density, in chronic hyperoxia and hypercapnia in the mouse cerebral cortex -- Oxygen delivery: the principal role of the circulation -- Heart rate variability in newborns with hypoxic brain injury -- Part 2. Brain oxygenation -- Simultaneous monitoring of brain and skin oxygenation during haemorrhagic shock in piglets -- Hemispheric differences of motor execution: a near-infrared spectroscopy study -- Acute stress exposure preceding global brain ischemia accelerates decreased doublecortin expression in the rat retrosplenial cortex -- Effects of transcranial direct current stimulation of the motor cortex on prefrontal cortex activation during a neuromuscular fatigue task: an fNIRS study -- Effect of inner speech on arterial CO2, cerebral hemodynamics and oxygenation: a functional NIRS study -- Investigation of frontal lobe activation with fNIRS and systemic changes during video gaming -- Effect of valsalva maneuver-induced hemodynamic changes on brain near-infrared spectroscopy measurements -- Cerebral autoregulation in premature infants -- Brain tissue oxygen saturation increases during sleep in adolescents -- Changes of cerebral oxygen metabolism and hemodynamics during ECPR with hypothermia measured by near infrared spectroscopy: a pilot study -- Part 3. Muscle oxygenation -- Analysis of NIRS-based muscle oxygenation parameters by inclusion of adipose tissue thickness -- Statistical treatment of oxygenation-related data in muscle tissue -- O2 saturation in the intercostal space during moderate and heavy constant-load exercise -- Muscle, prefrontal and motor cortex oxygenation profiles during prolonged fatiguing exercise -- Aging affects spatial distribution of leg muscle oxygen saturation during ramp cycling exercise -- Which is the best indicator of muscle oxygen extraction during exercise using NIRS?: evidence that HHb is not the candidate -- Tissue oxygenation during exercise measured with NIRS: reproducibility and influence of wavelengths -- Using portable NIRS to compare arm and leg muscle oxygenation during roller-skiing in bi-athletes: a case study -- Use of portable NIRS to measure muscle oxygenation and haemodynamics during a repeated sprint running test -- Part 4. Tumor oxygenation -- Amifostine acts upon mitochondria to stimulate growth of bone marrow and regulate cytokines -- Hypoxia, lactate accumulation and acidosis: siblings or accomplices driving tumor progression and resistance to therapy? -- Breast cancer detection of large size to DCIS by hypoxia and angiogenesis using NIRS -- Impact of extracellular acidosis on intracellular pH control and cell signaling in tumor cells -- Tumor oxygenation: an appraisal of past and present concepts, and a look into the future -- In vivo metabolic evaluation of breast tumor mouse xenografts for predicting aggressiveness using the hyperpolarized 13C-NMR technique -- Mapping the redox state of chop-treated non-Hodgkin's lymphoma xenografts in mice -- Maternal bias in mouse radiosensitivity. the role of the mitochondrial PTP -- Interleukin 11 protects bone marrow mitochondria from radiation damage -- Tumor reoxygenation following administration of the EGFR inhibitor, gefitinib, in experimental tumors -- radiation affects the responsiveness of bone marrow to G-CSF -- Application of MOBILE (mapping of oxygen by imaging lipids relaxation enhancement) to study variations in tumor oxygenation -- Primo vascular system and its potential role in cancer metastasis -- Part 5. Cell metabolism -- Pancreaticoduodenectomy using perioperative zymogen protein C to help prevent blood clotting: a trilogy on increased patient safety -- Inhibition of mammalian target of rapamycin induces renal mitochondrial uncoupling in rats -- Molecular hydrogen consumption in the human body during the inhalation of hydrogen gas -- Oxidative metabolism: glucose vs ketones -- Part 6. System modelling -- Modelling blood flow and metabolism in the piglet brain during hypoxia-ischaemia. simulating pH changes -- Modelling blood flow and metabolism in the piglet brain during hypoxic-ischaemia. simulating brain energetics -- Mathematical modelling of near infrared spectroscopy signals and intracranial pressure in brain injured patients -- Dependence on NIRS source-detector spacing of cytochrome C oxidase response to hypoxia and hypercapnia in the adult brain -- Modeling hemoglobin nitrite reductase activity as a mechanism of hypoxic vasodilation? -- Part 7. Measurement technologies -- Development of a hybrid microwave-optical tissue oxygenation probe to measure thermal response in the deep tissue -- Oxygen sensitive quantum dots for possible nano-scale oxygen imaging in cultured cells -- Boron tracedrug design for neutron dynamic therapeutics for LDL -- New method of analysing NIRS data from prefrontal cortex at rest -- Radiation oxygen biology with pulse electron paramagnetic resonance imaging in animal tumors -- Wavelength selection for the improvement of the signal to noise ratio for imaging of haemoglobin oxygenation with RGB reflectometry -- Improving pulse oximetry accuracy by removing motion artifacts from photoplethysmograms using relative sensor motion: a preliminary study -- Measuring the vascular diameter of brain surface and parenchymal arteries in awake mouse -- Simultaneous imaging of cortical blood flow and haemoglobin concentration with LASCA and RGB reflectometry -- Quality evaluation method for rat brain cryofixation based on NADH fluorescence -- Cerebral cortex activation mapping upon electrical muscle stimulation by 32-channel time domain functional near infrared spectroscopy -- NIRS-based neurofeedback learning systems for controlling activity of the prefrontal cortex -- Cortical mapping of 3D optical topography in infants -- Monitoring of hemodynamic change in patients with carotid artery stenosis during the tilt test using wearable near-infrared spectroscopy.
    Also available: Print – 2013
  • 2014From: Springer
    Harold M. Swartz, David K. Harrison, Duane F. Bruley, editors.
    Mitochondrial genetic abnormalities after radiation exposure -- Crediting six discoverers of oxygen -- Hypoxia in tumors: pathogenesis-related classifi cation, characterization of hypoxia subtypes, and associated biological and clinical implications -- Heterogeneity in tissue oxygenation: from physiological variability in normal tissues to pathophysiological chaos in malignant tumours -- Oxygen diffusion: an enzyme-controlled variable parameter -- Role of microvascular shunts in the loss of cerebral blood flow autoregulation -- Impact of hypoxia-related tumor acidosis on cytotoxicity of different chemotherapeutic drugs in vitro and in vivo -- The founding of ISOTT: the Shamattawa of engineering science and medical science -- A tale of two methods: combining near- infrared spectroscopy with MRI for studies of brain oxygenation and metabolism -- Advances in probes and methods for clinical EPR oximetry -- Real-time, in vivo determination of dynamic changes In lung and heart tissue oxygenation using EPR oximetry -- Modulation of hypoxia by magnetic nanoparticle hyperthermia to augment therapeutic index -- Skeletal muscle and glioma oxygenation by carbogen inhalation in rats: a longitudinal study by EPR oximetry using single-probe implantable oxygen sensors -- Recurrent low-dose chemotherapy to inhibit and oxygenate head and neck tumors -- How in vivo EPR measures and images oxygen -- What we learn from in vivo EPR oxygen images -- EPR image based oxygen movies for transient hypoxia -- Repetitive measurements of intrarenal oxygenation in vivo using L band electron paramagnetic resonance -- Quantitative hypoxia imaging for treatment planning of radiotherapy -- A new flavonoid regulates angiogenesis and reactive oxygen species production -- Angiotensin II reduces transport-dependent oxygen consumption but increases transport-independent oxygen consumption in immortalized mouse proximal tubular cells -- Investigation of cerebral autoregulation In the newborn piglet during anaesthesia and surgery -- Influence of the maternal use of labetalol on the neurogenic mechanism for cerebral autoregulation assessed by means of NIRS -- Development of a near infrared multi- wavelength, multi-channel, time-resolved spectrometer for measuring brain tissue haemodynamics and metabolism -- Simulating NIRS and MRS measurements during cerebral hypoxia-ischaemia in piglets using a computational model -- Analysis of slow wave oscillations in cerebral haemodynamics and metabolism following subarachnoid haemorrhage -- Effects of enriched environment on hippocampal neuronal cell death and neurogenesis in rat global ischemia -- Automated image analysis for diameters and branching points of cerebral penetrating arteries and veins captured with two-photon microscopy -- Cerebral hemodynamic change and metabolic alteration in severe hemorrhagic shock -- Physiological mechanism of increase In deoxy-hemoglobin concentration during neuronal activation in patients with cerebral ischemia: a simulation study with the balloon model -- Effect of blood in the cerebrospinal fluid on the accuracy of cerebral oxygenation measured by near infrared spectroscopy -- Vessel specifi c imaging of glucose transfer with fluorescent glucose analogue in anesthetized mouse cortex -- Ischemic pretreatment delays ischemic brain vasospasm Injury in gerbils -- Changes in cerebral blood oxygenation induced by active standing test in children with POTS and NMS -- Optical imaging of brain activation in Gambian infants -- Asymmetrical changes in cerebral blood oxygenation induced by an active standing test in children with postural tachycardia syndrome -- Changes of cerebral tissue oxygen saturation at sleep transitions in adolescents -- Influence of subjective happiness on the prefrontal brain activity: an fNIRS study -- Ginkobiloba extract improves working memory performance in middle-aged women: role of asymmetry of prefrontal cortex activity during a working memory task -- Bayesian prediction of anxiety level in aged people at rest using 2-channel NIRS data from prefrontal cortex -- Short-term hypoxic preconditioning improved survival following cardiac arrest and resuscitation in rats -- Venular valves and retrograde perfusion -- Monitoring of filter patency during carotid artery stenting using near-infrared spectroscopy with high time-resolution -- Use of NIRS to assess effect of training on peripheral muscle oxygenation changes in elite rugby players performing repeated supramaximal cycling tests -- Skeletal muscle deoxygenation responses during treadmill exercise in children -- Development of a hybrid microwave-optical thermoregulation monitor for the muscle -- Evaluation of a textile-based near infrared spectroscopy system in calf muscle oxygenation measurements -- Skin temperature in lower hind limb subjected to distal vein arterialization in rats.
    Also available: Print – 2014
  • 2016From: Springer
    Clare E. Elwell, Terence S. Leung, David K. Harrison, editors.
    This book contains the refereed contributions from the 42nd annual meeting of ISOTT. The annual meetings of ISOTT bring together scientists from various fields (medicine, physiology, mathematics, biology, chemistry, physics, engineering, etc.) in a unique international forum. ISOTT conferences are a place where an atmosphere of interaction is created, where many questions are asked after each presentation and lively discussions occur at a high scientific level. This vivid interaction is the main motivation for members to participate and gain new ideas and knowledge in the broad field of oxygen transport to tissue. The papers in this volume summarize some of the outstanding contributions from the 42nd annual meeting, which included sessions on: cellular hypoxia and mitochondria; blood substitutes and oxygen therapeutics; oxygen transport in critical care medicine and disease; muscle oxygenation; multi modal imaging techniques; brain oxygenation and imaging; optical techniques for oxygen measurement; microcirculation; mathematical modelling of oxygen transport; and cancer metabolism.
    Also available: Print – 2016
  • 2016From: Springer
    Qingming Luo, Lin Z. Li, David K. Harrison, Hua Shi, Duane F. Bruley, editors.
    Also available: Print – 2016
  • Sigrid Nachtergaele.
    The Hedgehog pathway is a highly conserved signaling cascade that coordinates embryonic development. Loss of function and aberrant activation of Hedgehog signaling have also been implicated in a variety of pathologies. The membrane protein Smoothened is a central signal transducer in this pathway, but how it is regulated is a longstanding mystery. It has been proposed that Smoothened has an endogenous small molecule ligand that could be regulated by the upstream regulator, Patched. Oxysterols are a class of endogenous cholesterol metabolites that can activate Hedgehog signaling, but their mechanism of action was a mystery. I focused on 20(S)-hydroxycholesterol (20(S)-OHC), the most potent activator out of the panel of oxysterols initially tested. Through pharmacological and biochemical analysis, I found that oxysterols target Smoothened through a site that is distinct from the one most other Smoothened drugs occupy. I went on to map the oxysterol binding site to the extracellular Smoothened cysteine rich domain (CRD). These studies revealed that the Smoothened CRD represents a crucial regulatory module of Smoothened in the context of endogenous signaling through Patched. Through the work presented here, I developed novel chemical tools that have allowed me to identify the mechanism by which oxysterols activate Hedgehog signaling through Smoothened. Most importantly, however, this work has revealed a conserved role for the Smoothened CRD in the regulation of Hedgehog signaling. It remains to be determined whether the Smoothened CRD directly receives a signal from Patched, or whether it plays a more indirect role in regulating signaling levels. Understanding this has important implications for the broader question of how Smoothened is regulated by Patched.
  • Scott Fraser Owen.
    Neural circuits throughout the brain are under the continuous influence of neuromodulators which shape network activity in accordance with behavioral context. Oxytocin is a key neuromodulator that has been linked to social memory and maternal behavior in animals, as well as to autism spectrum disorders, trust, emotion recognition and parenting in humans. Here we show that activation of oxytocin receptors sharpens the responses of the hippocampal circuit, increasing the signal of spike transmission through the network while simultaneously suppressing the noise of background spontaneous activity. Both of these actions are mediated through a depolarization of the fast-spiking interneurons. The resulting increase in inhibitory tone serves to silence spontaneous activity in the CA1 pyramidal cells, while a use-dependent depression of the inhibitory synapses permits enhanced feed-forward spike transmission. Furthermore, we show that oxytocin potently modulates spontaneous hippocampal Sharp-Wave Ripple oscillations in a slice preparation. These results elucidate the action of oxytocin in the hippocampus, while simultaneously shedding light on a novel mechanism by which modulation of fast-spiking interneurons can modify hippocampal circuit activity.
  • 2011From: Springer
    Velio Bocci.
    Physical-chemical properties of ozone: natural production of ozone: the toxicology of ozone -- How ozone is generated and its concentrations measured? -- Preparation of ozonated water and oil for the topical therapy: ozone as a drinking water disinfectant: ozone disinfection to prevent nosocomial infections -- How does ozone act?: how and why can we avoid ozone toxicity? -- How is ozone administered? -- The actual six therapeutic modalities -- The potential toxicity of ozone: side effects and contraindications of ozonetherapy -- Is ozone really a "wonder drug"? -- The clinical applications of ozonetherapy -- The dilemma between hyperbaric oxygen therapy (HOT) and ozone therapy -- The still uncertain future of ozone therapy in medicine.

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