BookHideaki E. Takahashi, David B. Burr, Noriaki Yamamoto, editors.
Summary: This edited book describes what fragile bone is, how the condition is assessed, and how it can be treated. It is intended for multi-professional trainees and practitioners in health and social care fields who care for and treat the elderly. Chapters within the book provide the latest advances in cell and molecular biology, morphology, radiology, and the biomechanics of bone in health and disease. The basic concept of Remodeling and Modeling is described for better understanding of the mechanisms of osteoporosis. Methods of identifying and assessing osteoporosis are described, as are risk factors for bone fracture and non-unions. Furthermore, the effects of various drugs used to treat osteoporosis at both material and structural levels of bone and their cost effectiveness are described. Operative treatments for fracture that maintain or improve the quality of life of patients are included Treatment of Osteoporotic Fracture and Systemic Skeletal Disorders attempts to provide a holistic and translational view of the pathogenesis and treatment of osteoporosis and some other musculoskeletal diseases, with an overview of treatment modalities in various clinical settings.
Contents:
Part I. Bone Morphometry, and Radiological Assessment
1. Past, Present and Future of Bone Histomorphometry
2. Effects of aging on bone fragility.-3. Cellular and molecular biology in bone remodeling
4. Modeling and Modeling-based bone formation in trabecular packets
5. A role of canopy and reversal cells in bone remodeling
6. Significance of reversal-resorption phase in cortical porosity
7. A role of focal osteoporosis defects in hip fracture
8. Bone Tissue and its mechanical regulation
9. Minimodeling, modeling-based formation, in human trabeculae and bone
10. Fracture healing and cause of non-union
11. Disturbance of osteonal remodeling in atypical femoral fracture
12. Microcrack and microdamage
13. 3D microstructure of bone tissue 14. 3D bone morphometry
15. DXA and SQ assessment of osteoporosis
16. Assessment of osteoporosis by HR-pQCT, QCT, MRI
17. FRAX (John A. Kanis)
Part II Metabolic and Systemic Disorders and Bone
18. Skeletal disorders on Hypovitamin D
19. Diabetes and bone
20. CKD-MBD
21. Ehlers-Danlos Syndrome, IgG4 related disorders and Hepatitis type C
Part III. Medical and Conservative Treatment
22. Effects of Osteoporosis Drugs BMD and Morphological Assessment.-23. Vibration as an exercise modality to prevent sarcopenia
Part IV Operative Treatment
24. Operative treatment of hip fracture
25. Balloon Kyphoplasty
26. Operative treatment of spinal disorders with consideration of dynamic axis of spinal column and lower extremities
27. Operative treatment of spinal disorders with minimum invasive technique.