BookStephen K. Tyring, Stephen Andrew Moore, Angela Yen Moore, Omar Lupi, editors.
Summary: This book is a thorough, practical review of the challenges facing clinicians treating skin microbes and how to combat these therapeutic dilemmas. It expresses the critical public health concern of antimicrobial resistance and shows how microorganisms are developing the ability to halt the progress of antimicrobials like antibiotics, antivirals, and antifungals. Chapters are grouped together in five sections for ease of use. The first three sections of the book convey foundational information on the mechanisms of antibiotics, antivirals, and antifungals resistance, as well as the implications of lack of vaccination. The fourth section then turns to the specifics of drug resistance for protozoan and helminth infections focusing primarily on initial and subsequent resistance to treatment. The book closes with a discussion on the potential solutions of innovative therapy including new delivery mechanisms, broad-spectrum antibiotics, phytocompounds, and biofilms. Chapters feature magnified, microscopic photos for identifying structures as they appear on the skin. Part of the Updates in Clinical Dermatology series, Overcoming Antimicrobial Resistance of the Skin is an important resource relevant during the COVID-19 pandemic, and is written for all medical healthcare professionals.
Contents:
Section I: Emerging Bacterial Resistance to Antibiotics
Ch 1: Mechanisms of Bacterial Resistance
Ch 2: Emerging Bacterial Infections
Ch 3: Re-Emerging Bacterial Infections of the Skin
Section II: Emerging Resistance to Antivirals
Ch 4: Mechanisms of Nonretroviral Resistance
Ch 5: Mechanisms of Retroviral Resistance
Ch 6: Emerging Viral Infections
Ch 7: Re-Emerging Viral Infections - Implications of Lack of Vaccination
Section III: Emerging Resistance to Antifungals
Ch 8: Mechanisms of Antifungal Resistance
Ch 9: Emerging and Re-Emerging Fungal Infections
Section IV: Emerging Resistance to Drugs for Protozoan and Helminth Infections
Ch 10: Mechanisms of Anti-Protozoan/Helminth Drug Resistance
Ch 11: Emerging and Re-Emerging Protozoan/Helminth Infections
Section V: Innovative Therapies on the Forefront
Ch 12: Phage Therapy
Ch 13: The Role of Biofilms and the Microbiome
Ch 14: New Classes of Broad-Spectrum Antibiotics and New Mechanisms of Delivery
Ch 15: Phytocompounds
Ch 16: Summary: Overcoming Antimicrobial Resistance of the Skin.