- Wages and hours in private hospitals, California, 1958 — White matter injury in stroke and CNS disease (100)
- WHO application of ICD-10 to deaths during pregnancy, childbirth and puerperium : IDC MM. — World malaria report 2015 (100)
- World malaria report 2008 — Wyllie's Treatment of epilepsy : principles and practice. Sixth edition [6th ed.]. (30)
- Wharton, Marianna.Also available: Print – 1959
- Also available: Print – 1959
- 2009by Tom Harbin.
- 2012Pete B. Shull.Haptic feedback stimulates the skin and is useful for conveying information across the human body. Combining haptic feedback with movement sensing and computation in real-time can create a rich and diverse system for characterizing and retraining human movement. This thesis presents haptic gait retraining as a conservative treatment for individuals with medial compartment knee osteoarthritis. Wearable haptic feedback devices, which either vibrate or stretch the skin, are worn on the body and used to inform kinematic changes during walking. The focus of gait retraining is to shift loading away from the arthritic medial compartment of the knee by reducing the knee adduction moment - a clinically relevant measure that has been linked to pain, incidence, severity, and progression of medial compartment knee osteoathritis. Thus, training individuals with knee osteoarthritis to walk in a way that reduces the knee adduction moment has the potential to reduce knee pain, improve function, and slow osteoarthritis progression. Four experiments were conducted to explore the viability of haptic gait retraining. During all experiments, subjects walked on an instrumented treadmill while motion capture data was streamed in real-time and wearable haptic feedback was used to inform gait changes. In the first experiment, subjects received feedback of the knee adduction moment measurement and were given freedom to make kinematic changes to lower the knee adduction moment. All subjects demonstrated the ability to make gait modifications to acheive this goal, though some chose awkward gait patterns. In the second experiment, haptic feedback was used to inform changes to the foot progression angle as subjects were trained to ``toe-in'' more than they normally did. Toe-in gait proved to be an easy-to-learn gait pattern which reduced the knee adduction moment and looked natural. The purpose of the third experiment was to train simultaneous changes to multiple kinematic gait parameters. Subjects received haptic feedback for trunk sway, tibia, and foot progression angles to inform new gait patterns based on correlations between the knee adduction moment and each kinematic parameter. Subjects demonstrated large reductions in the knee adduction moment comparable to more invasive surgical interventions such as high tibial osteotomy. In the final experiment individuals with persistent knee pain and clinically diagnosed knee osteoarthritis participated in a six week gait retraining program to assess learning retention and symptom changes. Subjects demonstrated learning retention and at the end of the six weeks reported improvements in knee pain and function, which were significantly greater than from the expected placebo effect. This thesis shows that haptic gait retraining is a promising conservative treatment option for individuals suffering from medial compartment knee osteoarthritis. Haptic gait retraining has the potential to alter walking patterns which could over time reduce knee pain, slow osteoarthritis progression, and ultimately improve quality of life.
- v. 1-2, 2008.editors, Ronald E. Kleinman ... [et al.].
- 2013 ClinicalKeyedited by Stephen B. McMahon, Martin Koltzenburg, Irene Tracey, Dennis C. Turk.Also available: Print – 2013
- 2008editor, Robert B. Wallace ; associate editor, Neal Kohatsu ; editor emeritus, John M. Last ; section editors, Ross Brownson ... [et al.].Environmental justice: from global to local -- The health of hired farmworkers -- Women workers -- Health hazards of child labor -- Occupational safety and health standards -- Ensuring food safety -- Water quality management and water-borne disease trends -- Hazardous waste: assessing, detecting, and remediation -- Aerospace medicine -- Housing and health -- Human health in a changing world -- Health behavior research and intervention -- Tobacco: health effects and control -- Alcohol-related health problems -- Prevention of drug use and drug use disorders -- Community health promotion and disease prevention -- Risk communication-an overlooked tool for improving public health -- Health literacy -- Screening for early and asymptomatic conditions -- Cancer -- Heart disease -- Renal and urinary tract disease -- Diabetes -- Respiratory disease prevention -- Musculoskeletal disorders -- Neurological disorders -- Disabling visual disorders -- Psychiatric disorders -- Childhood cognitive disability -- Prevention of disability in older persons -- Nutrition in public health and preventive medicine -- Postmarketing medication safety surveillance: a current public health issue -- The American health-care system: structure and function -- Structure and function of the public health system in the United States -- International and global health -- Public health law -- Public health management tools -- Categorical public health sciences -- Injury control: the public health approach -- Violence in the family as a public health concern. Public health and preventive medicine: trends and guideposts -- Epidemiology and public health -- Ethics and public health policy -- Public health and population -- Public health informatics -- Health disparities and community-based participatory research: issues and illustrations -- Genetic determinants of disease and genetics in public health -- Control of communicable diseases -- Diseases controlled primarily by vaccination -- Epidemiology and trends in sexually transmitted diseases -- The epidemiology and prevention of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome (AIDS) -- Infection spread by close personal contact -- Diseases spread by food and water -- Control of infections in institutions: healthcare-associated infections -- Viral diseases transmitted primarily by arthropod vectors -- Diseases transmitted primarily from animals to humans (zoonoses) -- Opportunistic fungal infections -- Other infection-related diseases of public health import -- The status of environmental health -- Toxicology -- Environmental and ecological risk assessment -- Biomarkers -- Asbestos and other fibers -- Coal worker's lung diseases -- Silicosis -- Health significance of metal exposures -- Diseases associated with exposure to chemical substances: organic compounds -- Polychlorinated biphenyls -- Polychlorinated dioxins and polychlorinated dibenzofurans -- Brominated flame retardants -- Multiple chemical sensitivities -- Pulmonary responses to gases and particles -- Pesticides -- Temperature and health -- Ionizing radiation -- Nonionizing radiation -- Effects of the physical environment: noise as a health hazard -- Ergonomics and work-related musculoskeletal disorders -- Industrial hygiene -- Surveillance and health screening in occupational health -- Workers with disabilities --
- Wallach's Interpretation of diagnostic tests : pathways to arriving at a clnical diagnosis. Tenth edition [10th ed.]2015 Ovidedited by, Mary A. Williamson, MT (ASCP), PhD, Vice President, Scientific Affairs & Laboratory Operations, ACM Medical Laboratory, Rochester, New York, Former Assistant Professor, Department of Pathology, University of Massachusetts Medical School, Worcester, Massachusetts, L. Michael Snyder, MD, Professor, Department of Medicine and Pathology, University of oMassachusetts Medical School, UMass Memorial Medical Center, Worcester, Massachusetts, Cheif Medical Officer, Quest Diagnostics MA, LLC, Marlborough, Massachusetts."Wallach's Interpretation of Diagnostic Tests, 10th Edition serves as a practical guide to the use of laboratory tests which aids physicians in using tests more effectively and efficiently by offering test outcomes, possible meanings, differential diagnosis, and summaries of tests available. The book is organized into 2 sections. The first section is devoted to disease states. Where appropriate, a patient's chief complaint and/or physical findings are initially presented with subsequent discussions focused on discrete disease states as they relate to a patient's chief complaint. The second section is devoted to an alphabetical listing of laboratory tests while stressing the integration of the clinical laboratory in the clinical decision making process. Test sensitivity, specific and possible and negative probabilities are included whenever appropriate. Microbiology tests are listed in a separate chapter"--Provided by publisher.
- 2011 Ovidedited by Mary A. Williamson with L. Michael Snyder.Introduction to laboratory medicine / Rao -- Laboratory tests -- Laboratory cultures -- Cardiovascular diseases / Vallaro & Pechet -- Central nervous system disorders / Szakacs -- Digestive diseases / Snyder -- Endocrine diseases / Yu -- Genitourinary diseases / Pechet & Kiefer -- Gynecologic and obstetric disorders / Pechet -- Hematologic diseases / Pechet -- Hereditary and genetic diseases -- Immune and autoimmune disorders / Pechet -- Infectious diseases / Mitchell -- Miscellaneous / Snyder -- Respiratory, metabolic, and acid-base disorders / Rao -- Toxicology and therapeutic drug monitoring / Jenkins.
- 2005 Ovid[editors] Neil R. Miller, Nancy J. Newman, Valérie Biousse, John B. Kerrison.V. 1 -- Sect. I Visual sensory system -- Sect. II The Autonomic nervous system -- Sect. III The Ocular motor system -- Sect. IV The Eyelid -- Sect. V Facial pain and headache -- Sect. VI Nonorganic disease -- V. II -- Sect. VII Tumors -- Sect. VIII The Phacomatoses -- Sect. IX Vascular disease -- V. III -- Sect. X Degenerative and metabolic diseases -- Sect. XI Infectious, inflammatory, and demyelinating diseases.Also available: Print – v. 1-3, 2005.
- 2008editors, Neil R. Miller, Nancy J. Newman, Valérie Biousse, John B. Kerrison.Examination of the visual sensory system -- Anatomy and physiology of the retina and optic nerve: distinguishing retinal from optic nerve disease -- Congenital anomalies of the optic disc -- Topical diagnosis of acquired optic nerve disorders -- Papilledema -- Optic neuritis -- Ischemic optic neuropathies -- Compressive and infiltrative optic neuropathies -- Traumatic optic neuropathies -- Toxic and deficiency optic neuropathies -- Hereditary optic neuropathies -- Topical diagnosis of chiasmal and retrochiasmal lesions -- Central disorders of visual function -- Examination of the pupils, accommodation, and lacrimation -- Disorders of pupillary function, accommodation, and lacrimation -- Examination of ocular motility and alignment -- Supranuclear and internuclear ocular motor disorders -- Nuclear and infranuclear ocular motility disorders -- Disorders of neuromuscular transmission -- Myopathies affecting the extraocular muscles -- Nystagmus and related ocular motility disorders -- Normal and abnormal eyelid function -- Neuro-ophthalmologic manifestations of nonorganic disease.
- editors, Neil R. Miller [and others].Examination of the visual sensory system -- Anatomy and physiology of the retina and optic nerve -- Congenital anomalies of the optic disc -- Topical diagnosis of acquired optic nerve disorders -- Papilledema -- Optic neuritis -- Ischemic optic neuropathies -- Compressive and infiltrative optic neuropathies -- Traumatic optic neuropathies -- Toxic and deficiency optic neuropathies -- Hereditary optic neuropathies -- Topical diagnosis of chiasmal and retrochiasmal lesions -- Central disorders of visual function -- Examination of the pupils and accommodation -- Disorders of pupillary function and accommodation -- Examination of ocular motility and alignment -- Supranuclear and internuclear ocular motor disorders -- Nuclear and infranuclear ocular motility disorders -- Disorders of neuromuscular transmission -- Myopathies of neuro-ophthalmologic significance -- Nystagmus and related ocular motility disorders -- Normal and abnormal eyelid function -- Neuro-ophthalmologic manifestations of nonorganic disease.
- 2011Barbara Newborg ; with Florence Nash.Ricers -- Family and early childhood -- Education : Heidelberg and Berlin -- Crisis and diaspora -- A new home -- Neu Dahlem -- Development of the rice diet -- Results -- Kudos and controversy -- The rice houses -- In the laboratory -- Building the financial foundations -- The gadfly.
- 2008edited by Barry S. Levy, Victor W. Sidel ; [foreword by Jimmy Carter].War and public health: an overview -- The epidemiology of war -- War and human rights -- The impact of war on mental health -- The impact of war on the environment -- Conventional weapons -- Landmines -- Chemical weapons -- Biological weapons -- Nuclear weapons -- The impact of war on children -- The impact of war on women -- Displaced persons and war -- Detainees and the new face of torture -- The Iraq war -- The war in Chechnya -- War in the Democratic Republic of Congo -- Wars in Latin America -- The Vietnam War -- A public health approach to preventing the health consequences of armed conflict -- International law -- The roles of humanitarian assistance organizations -- The roles of nongovernmental organizations -- The roles and ethical dilemmas for military medical care workers -- The roles of health professionals in postconflict situations -- Peacemaking in the aftermath of disasters -- Educating health professionals on peace and human rights -- Toward a culture of peace.
- War in the body : the evolutionary arms race between HIV and the human immune system and the implications for vaccines2013 SpringerW. David Wick, Otto O. Yang.In the relatively few decades since the introduction of HIV into the human population, variants of the virus have diverged to such an extent that, were the discussion about something other than viruses, said variants could easily be classified as different species. This book will consider these evolutionary variations, as well as the different and, at times, opposing theories attempting to explain them. It will compare and contrast the ways in which the immune system and drugs affect the virus's evolution, and the implications of these for vaccine development. The issue will be explored and explained through "ecological genetics," which postulates that all living organisms have, besides rivals, enemies. This is divergent from the more traditional school of "population genetics," which emphasizes that evolution occurs among rival species (or variants thereof) that compete for niches or resources in a fixed, unreactive environment. Both models will be formulated using mathematical models, which will be included in the book. Finally, it will consider the possibilities for designing a vaccine that blocks HIV from escaping the immune system.
- 2016 Kargervolume editors, L. Tatu, J. Bogousslavsky.Neurology and war : from antiquity to modern times / Paciaroni, M., Arnao, V. -- Neurosurgical work during the Napoleonic wars : George James Guthrie's experience / Roux, F.-E -- Impact of 20th century wars on the development of neurosurgery / Dowdy, J., Pait, T.G. -- Elaboration of the visual pathways from the study of war-related cranial injuries : the period from the Russo-Japanese War to World War I / Lanska, D.J. -- Publications on peripheral nerve injuries during World War I : a dramatic increase in knowledge / Koehler, P.J. -- The influence of the two world wars on the development of rehabilitation for spinal cord injuries in the United States and Great Britain / Lanska, D.J. -- Traumatic brain injury studies in Britain during World War II / Lanska, D.J. -- Neurology and neurologists during the Franco-Prussian War (1870-1871) / Walusinski, O. -- Silas Weir Mitchell : neurologists and neurology during the American Civil War / Boller, F., Birnbaum, .D -- Fench neurologists during World War I / Walusinski, O., Tatu, L., Bogousslavsky, J. -- Nostalgia in the army (17th-19th centuries) / Battesti, M. -- Neuropsychiatric disturbances, self-mutilation and malingering in the French armies during World War I : war strain or cowardice? / Tatu, L., Bogousslavsky, J. -- Neurological impact of World War I on the artistic avant-garde : the examples of André Breton, Guillaume Apollinaire and Blaise Cendrars / Bogousslavsky, J., Tatu, L. -- The central role of neuroscientists under National Socialism / Zeidman, L.A. -- What's in a name? : neurological eponyms of the Nazi era / Kondziella, D., Zeidman, L.A -- Neurology in the vietnam war / Gunderson, C.H., Daroff, R.B -- Neurotoxic weapons and syndromes / Carota, A., Calabrese, P., Bogousslavsky, J. -- Post-traumatic stress disorder among French armed forces members in Afghanistan : a new approach / Paul, F., Marimoutou, C., Pommier de Santi, Clervoy, P.
- 2012 ClinicalKeyedited by Andrew J. Davey, Ali Diba.The supply of anaesthetic and other medical gasses -- Measurement of pressure and gas flow -- Vaporizers -- The anaesthetic workstation -- Breathing systems and their components -- Airway management equipment -- Equipment for the inhalation of oxygen and other gasses -- Manual resuscitators -- Automatic ventilators -- Ventilation in the intensive care unit -- Breathing filters, humidifiers and nebulizers -- Equipment for paediatric anaesthesia -- Equipment for regional anaesthesia -- Physiological monitoring : Principles and non-invasive monitoring -- Physiological monitoring : Gasses -- Cardiac output monitoring -- Depth of anaesthesia and neurophysiological monitoring -- Atmospheric pollution -- Infusion equipment and intravenous anaesthesia -- Medical suction apparatus -- Cleaning, disinfection and sterilization -- Information technology and the anaesthetic workstation -- Electrical hazards and their prevention -- Surgical diathermy -- Pacemakers and defibrillators -- Lasers -- Provision of anaesthesia in difficult situations and the developing world -- The anaesthetist and the Medicines and Healthcare products Regulatory Agency -- Error, Man and Machine -- Warming devices -- Physics and technology of ultrasound -- Appendix SI units and conversion tables.
- 2016 Ovideditor, James Matthew Freer.1. Central venous cannulation -- 2. Radial arterial line placement -- 3. Endotracheal intubation -- 4. Lumbar puncture -- 5. Abdominal paracentesis -- 6. Thoracentesis -- 7. Knee arthrocenetesis.
- 2012[edited by] Marin H. Kollef, Warren Isakow.
- 2008[edited by] Marin H. Kollef ... [et al.].
- 2016[edited by] M. Laurin Council, David M. Sheinbein, Lynn A. Cornelius.The skin exam / Rebecca Chibnall and Arthur Eisen -- Basic science of the skin / Karl Staser and Shadmehr Demehri -- Inflammatory disorders / Emily Beck and Sena Lee -- Infections and infestations / Heather Jones and Kara Sternhell-Blackwell -- Reactive disorders and drug eruptions / Shivani Tripathi and Milan Anadkat -- Disorders of pigmentation / Shaanan Shetty and Caroline Mann -- Benign skin lesions / Shayna Gordon and M. Laurin Council -- Malignant skin lesions / David Chen and Lynn Cornelius -- Disorders of the hair and nails / Katherine Moritz and Ann Martin -- Cutaneous manifestations of systemic disease / Urvi Patel and Amy Musiek -- Dermatologic surgery / Christopher Urban and Eva Hurst -- Pediatric dermatology / Kara Sternhell-Blackwell, Monique Kumar, and Susan Bayliss -- Geriatric dermatology / Kathleen Nemer and David Sheinbein -- Sun safety / Rachel Braden and Kimberly Brady -- Dermatologic therapies / Kyle Eash and Ian Hornstra -- Differential diagnoses appendices / Jamie Mull and M. Laurin Council.
- 2017 Ovideditor, Nishath Quader ; associate editors, Majesh Makan, Julio E. Pérez.1.Introduction to Echocardiographic Principles / Suzanne V. Arnold -- 2.The Comprehensive Transthoracic Echocardiographic Examination / David S. Raymer -- 3.The Role of Contrast in Echocardiography / Majesh Makan -- 4.Quantification of Left Ventricular Systolic and Diastolic Function / Christopher L. Holley -- 5.Right Ventricular Function and Pulmonary Hemodynamics / Nishath Quader -- 6.Stress Testing for Ischemia and Viability / Daniel H. Cooper -- 7.Ischemic Heart Disease and Complications of Myocardial Infarction / Michael Yeung -- 8.Cardiomyopathies / Christopher L. Holley -- 9.Hypertrophic Cardiomyopathy / Sharon Cresci -- 10.Aortic Valve Disease / Jacob S. Goldstein -- 11.Mitral Valve Disease / Nishath Quader -- 12.Pulmonic Valve / Julio E. Perez -- 13.Tricuspid Valve Disorders / Julio E. Perez -- 14.Evaluation of Prosthetic Valves / Jose A. Madrazo -- 15.Infective Endocarditis / Nishath Quader -- 16.Pericardial Disease and Cardiac Tamponade / Michael Yeung -- 17.Diseases of the Great Vessels: Aorta and Pulmonary Artery / Nishath Quader -- 18.Congenital Heart Disease / Majesh Makan -- 19.Cardiac Masses / Justin S. Sadhu -- 20.Cardiac Manifestations of Systemic Illness / Justin M. Vader -- 21.Transesophageal Echocardiography / Nishath Quader -- 22.Cardiac Devices in Heart Failure / Justin M. Vader.Also available: Print – 2017
- 2013editor, Ravi Rasalingam ; associate editors, Majesh Makan, Julio E. Pérez.
- 2010, 2014, 2016 Ovid2014 (34th ed.) Ovid2010 (33rd ed.) OvidAlso available: Print – 1998-2004, 2010, <2016>
- 2008editor, Ramaswamy Govindan.
- 2015 Ovid[edited by] Ramaswamy Govindan and Daniel Morgensztern.Also available: Print – 2015
- executive editor, Thomas M. De Fer ; editor, Heather Sateia.Also available: Print – 2015
- 2016editors, Emily Fondahn, Michael Lane, Andrea Vannucci.
- 2009editors, Susan M. Dusenbery, Andrew J. White.Patient care / by Susan Dusenbery and Andrew White -- Nutritional problems / by William Bennett and James Keating -- Fluid and electrolyte management / by Susan Dusenbery and James Keating -- Emergencies / by Marcella Donaruma-Kwoh and Robert Kennedy -- Poisonings / by Marcella Donaruma-Kwoh -- Orthopedics / by Marcella Donaruma-Kwoh and Robert Kennedy -- Newborn medicine / by Akshaya Vachharajani and Amit Mathur -- Critical care / by Nathan Dean and Nikoleta Kolovos -- Surgery / by Li Ern Chen and Brad Warner -- Adolescent medicine / by Sarah Tycast and Katie Plax -- Allergic diseases / by Leonard Bacharier ... [et al.] -- Cardiac concerns / by Mark Johnson and Edward K. Rhee -- Dermatologic diseases / by Kara Sternhell Nunley and Susan J. Bayliss -- Endocrine diseases / by Ana Maria Arbelaez, Arpita Kalla, and Stacie P. Shepherd -- Gastroenterologic diseases / by William Bennett and James Keating -- Genetic diseases / by Tracy McGregor and Tyler Reimschisel -- Hematology-oncology / by Aarati Rao and David B. Wilson -- Infectious diseases / by Stephanie A. Fritz and David A. Hunstad -- Neurologic diseases / by Amit Malhotra and Christina A. Gurnett -- Pulmonary diseases / by Katherine Rivera-Spoljaric and Leonard Bacharier -- Radiologic concerns / by Keith A. Kronemer and William H. McAlister -- Renal diseases / by Sweety Srivastava and Anne Beck -- Rheumatologic diseases / by Megan A. Cooper and Andrew White -- Sedation / by Lynne Strauser Sterni ... [et al.] -- Formulary / by Kristina N. Bryowsky.
- 2016 Ovideditor, Andrew J. White.Also available: Print – 2016
- 2016 Ovideditors, Mary E. Klingensmith, Chandu Vemuri, Oluwadamilola M. Fayanju, Pamela P. Samson, Jason O. Robertson, Dominic E. Sanford ; foreword by Timothy J. Eberlein.Also available: Print – 2016
- 2008 OvidDepartment of Surgery, Washington University School of Medicine, St. Louis, Missouri ; [edited by] Mary E. Klingensmith ... [et al.] ; foreword by Timothy J. Eberlein.Also available: Print – 2008
- 2012editors, Mary E. Klingensmith ... [et al.] ; foreword by Timothy J. Eberlein.
- 2008editors, Peter A. Humphrey, Louis P. Dehner, John D. Pfeifer.
- 2012editors, Peter A. Humphrey, Louis P. Dehner, John D. Pfeifer.
- 2006 Ovideditor, Adrian Shifren.
- 2015European Monitoring Centre for Drugs and Drug Addiction.Wastewater analysis is a rapidly developing scientific discipline with the potential for monitoring real-time population-level trends in illicit drug use. Originally used in the 1990s to monitor the environmental impact of liquid household waste, the method has since been used to estimate illicit drug consumption in different cities (Daughton, 2001; Zuccato et al., 2008; van Nuijs et al., 2011). It involves sampling a source of wastewater, such as a sewage influent to a wastewater treatment plant. This allows scientists to estimate the quantity of drugs consumed in a community by measuring the levels of illicit drugs and their metabolites excreted in urine (Zuccato et al., 2008).
- 2011 Springerby Iván Francisco García-Tejero, Víctor Hugo Durán-Zuazo, José Luis Muriel-Fernández, Carmen Rocío Rodríguez-Pleguezuelo.Irrigated agriculture, a vital component of general agriculture, supplies fruits, vegetables, and cereals consumed by humans and grains fed to animals. Consequently, agriculture is the largest user of fresh water globally, and irrigation practices in many parts of the world are biologically, economically, and socially unsustainable. Water management should balance the need for agricultural water and the need for a sustainable environment. Water-use efficiency is the prime challenge in worldwide farming practices where problems of water shortages are widespread. Currently, agriculture is undergoing significant changes in innovative irrigation, fertilizer technology, and agronomic expertise. These elements constitute a vital platform for sustainable agricultural success and for preventing environmental damage. This review presents several processes linked to environmental irrigation, balancing environmental protection with improved agricultural production.
- 2006 Springeredited by Gerald H. Pollack, Ivan L. Cameron, Denys N. Wheatley.
- 2007 CRCnetBASEeditors, Pedro Fierro, Jr. and Evan K. Nyer.
- 2011 WHOedited by David Cunliffe ... [et al.]."This document provides guidance for managing water supplies in buildings where people may drink water; use water for food preparation; wash, shower, swim or use water for other recreational activities; or be exposed to aerosols produced by water-using devices, such as cooling towers. These uses occur in a variety of buildings, such as hospitals, schools, child and aged care, medical and dental facilities, hotels, apartment blocks, sport centers, commercial buildings and transport terminals"--Publisher's description.Also available: Print – 2011
- 2009[contributions by J. Bartram ... [et al.]].
- Water safety planning for small community water supplies : step-by-step risk management guidance for drinking-water supplies in small communities2012 WHO[Robert Bos, coordinator].Also available: Print – 2012
- 2009 WHOedited by John Adams, Jamie Bartram, Yves Chartier, Jackie Sims."Diseases related to inadequate water, sanitation and hygiene are a huge burden in developing countries. It is estimated that 88% of diarrhoeal disease is caused by unsafe water supply, and inadequate sanitation and hygiene (WHO, 2004c). Many schools serve communities that have a high prevalence of diseases related to inadequate water supply, sanitation and hygiene, and where child malnutrition and other underlying health problems are common. Schools, particularly those in rural areas, often completely lack drinking-water and sanitation and handwashing facilities; alternatively, where such facilities do exist they are often inadequate in both quality and quantity. Schools with poor water, sanitation and hygiene conditions, and intense levels of person-to-person contact, are high-risk environments for children and staff, and exacerbate children's particular susceptibility to environmental health hazards. Children's ability to learn may be affected by inadequate water, sanitation and hygiene conditions in several ways. These include helminth infections (which affect hundreds of millions of school-age children), long-term exposure to chemical contaminants in water (e.g. lead and arsenic), diarrhoeal diseases and malaria infections, all of which force many schoolchildren to be absent from school. Poor environmental conditions in the classroom can also make both teaching and learning very difficult. Girls and boys are likely to be affected in different ways by inadequate water, sanitation and hygiene conditions in schools, and this may contribute to unequal learning opportunities. Sometimes, girls and female teachers are more affected than boys because the lack of sanitary facilities means that they cannot attend school during menstruation. The international policy environment increasingly reflects these issues. Providing adequate levels of water supply, sanitation and hygiene in schools is of direct relevance to the United Nations (UN) Millennium Development Goals of achieving universal primary education, promoting gender equality and reducing child mortality. It is also supportive of other goals, especially those on major diseases and infant mortality." - p. iiiAlso available: Print – 2009
- 2012 SpringerOlaf Stanger, editor.Biotin: biochemical, physiological and clinical aspects -- Niacin status and genomic instability in bone marrow cells: mechanisms favoring the progression of leukemogenesis -- Niacin: vitamin and antidyslipidemic drug -- Beyond the antioxidant: the double life of vitamin C -- Vitamin C in sepsis -- Vitamin C transport and its role in the cental nervous system -- Genetic aspects of folate metabolism -- Enzymatic and non-enzymatic antioxidative effects of folic acid and its reduced derivates -- Folate-linked drugs for the treatment of cancer and inflammatory diseases -- Folate in skin cancer prevention -- Thiamin(e): the spark of life -- Riboflavin in development and cell fate -- Vitamins B6 and cancer -- Vitamin B6 and cardiovascular disease -- Vitamin B6: beyond coenzyme functions -- Cobalamin deficiency -- Biochemistry of B12-cofactors in human metabolism -- Physiological and molecular aspects of cobalamin transport.
- 2014 ScienceDirectedited by Helen Bridle.1.Introduction / Helen Bridle -- References -- 2.Overview of Waterborne Pathogens / Helen Bridle -- 2.1.Viruses -- 2.2.Bacteria -- 2.3.Protozoa -- 2.4.Helminths -- 2.5.Summary -- Acknowledgment -- References -- 3.Existing Methods of Waterborne Pathogen Detection / James Green -- 3.1.World health organisation guidelines -- 3.2.Types of monitoring -- 3.3.Fecal indicator monitoring -- 3.4.Direct detection of pathogens -- 3.5.Summary -- References -- 4.Sample Processing / Anna C. Schultz -- 4.1.Background -- 4.2.Sampling -- 4.3.Concentration techniques -- 4.4.Secondary concentration techniques -- 4.5.Nuclei acid extraction for molecular detection -- 4.6.Analytical controls -- 4.7.Summary -- References -- 5.Optical Detection Technologies for Waterborne Pathogens / Helen Bridle -- 5.1.Techniques using labeling -- 5.2.Spectroscopy -- 5.3.Summary -- References -- 6.Electrochemical Detection / Vincent Senez -- 6.1.Introduction -- 6.2.Potentiometry -- 6.3.Voltammetry -- 6.4.Coulometry -- 6.5.Impedance spectroscopy -- 6.6.Dielectrophoresis -- 6.7.Scaling effect -- 6.8.Miniaturized detection of waterborne pathogens -- 6.9.Summary and future outlook -- References -- 7.Biosensors for the Detection of Waterborne Pathogens / Marc Desmulliez -- 7.1.Performance characteristics -- 7.2.Recognition elements -- 7.3.Transduction methods -- 7.4.Biosensors for waterborne viruses -- 7.5.Biosensors for waterborne bacteria -- 7.6.Biosensors for waterborne protozoa -- 7.7.Biosensors for the detection of waterborne parasites -- 7.8.Summary and future outlook -- References -- 8.Molecular Methods for the Detection of Waterborne Pathogens / Kimberley Gilbride -- 8.1.Why molecular methods? -- 8.2.Molecular methods -- 8.3.Current state of pathogen detection in water sources -- 8.4.Fecal source tracking -- 8.5.Summary and future outlook -- References -- 9.Nanotechnology for Detection of Waterborne Pathogens / Helen Bridle -- 9.1.Introduction -- 9.2.Background -- 9.3.Nanotechnology in sample processing -- 9.4.Nanotechnology in pathogen detection -- 9.5.Summary -- References -- 10.Miniaturized Detection Systems / Helen Bridle -- 10.1.Microfluidics -- 10.2.Applications -- 10.3.Summary -- References -- 11.Applications of Emerging Technologies in the Drinking Water Sector / Graham Sprigg -- 11.1.Current position of the UK water industry -- 11.2.Application of WSPs and WSF in the rest of the world -- 11.3.The legislative framework -- 11.4.Pathogens of major concern to the market -- 11.5.Public health policy implications for detection and treatment -- 11.6.Detection and treatment from a market perspective -- 11.7.Market adoption of emerging technologies -- 11.8.Conclusions -- References -- 12.Conclusions / Helen Bridle -- 12.1.Summary -- 12.2.The future of waterborne pathogen monitoring.
- Wave length and action potentials : history of the International Federation of Clinical Neurophysiology2010Marc R. Nuwer, Carl H. Lücking.
- We are our brains : a neurobiography of the brain, from the womb to Alzheimer's. First U.S. Edition. [1st U.S. ed.]2014D. F. Swaab ; translated by Jane Hedley-Prôle."The culmination of renowned neuroscientist D.F. Swaab's life's work, We Are Our Brains unlocks the mysteries of the most complex organism in the human body, providing a fascinating overview of the brain's role in nearly every aspect of human existence. In short, engaging chapters, Swaab explains what is going on in our brains at every stage of life, including how a fetus's brain develops and the role that pregnancy plays in solidifying certain aspects of our identity; the radical neurological changes that occur during adolescence; what happens when we fall in love; and the neurological basis for a host of different disorders and personality traits."-- Publisher information.
- 2006 ProQuest SafariDoug Addison.
- 2007by Michael Schrenk.
- 2017 ClinicalKeyRonald B. Johnston.
- 2012 ScienceDirectRonald B. Johnston.The basics -- Diagnostic clues and "need to know" items -- Lichenoid reaction pattern -- Psoriasiform reaction pattern -- Spongiotic reaction pattern -- Vesiculobullous reaction pattern -- Granulomatous reaction pattern -- Vasculopathic reaction pattern -- Disorders of epidermal maturation and keratinization -- Disorders of pigmentation -- Disorders ofcollagen -- Disorders of elastic tissue -- Cutaneous mucinoses -- Cutaneous deposits -- Diseases of cutaneous appendages -- Cysts, sinuses, and pits -- Panniculitis -- Metabolic and storage diseases -- Miscellaneous conditions -- Cutaneous drug reactions -- Reactions to physical agents -- Cutaneous infections and infestations -- Bacterial and rickettsial infections -- Spirochetal infections -- Mycoses and algal infections -- Viral diseases -- Protozoal infections -- Marine injuries -- Helminth infestations -- Arthropod-induced diseases -- Tumors of the epidermis -- Lentigines, nevi, and melanomas -- Tumors of cutaneous appendages -- Fibrous tumors and tumor-like proliferations -- Tumors of fat -- Tumors of muscle, cartilage, and bone -- Neural and neuroendocrine tumors -- Vascular tumors -- Cutaneous metastases -- Cutaneous non-lymphoid infiltrates -- Cutaneous lymphomatous and leukemic infiltrates.
- 2016 ClinicalKeyJames W. Patterson ; contributor, Gregory A. Hosler.An approach to the interpretation of skin biopsies -- Diagnostic clues -- The lichenoid reaction pattern ('interface dermatitis') -- The psoriasiform reaction pattern -- The spongiotic reaction pattern -- The vesiculobullous reaction pattern -- The granulomatous reaction pattern -- The vasculopathic reaction pattern -- Disorders of epidermal maturation and keratinization -- Disorders of pigmentation -- Disorders of collagen -- Disorders of elastic tissue -- Cutaneous mucinoses -- Cutaneous deposits -- Diseases of cutaneous appendages -- Cysts, sinuses, and pits -- Panniculitis -- Metabolic and storage diseases -- Miscellaneous conditions -- Cutaneous drug reactions -- Reactions to physical agents -- Cutaneous infections and infestations: histological patterns -- Bacterial and rickettsial infections -- Spirochetal infections -- Mycoses and algal infections -- Viral diseases -- Protozoal infections -- Marine injuries -- Helminth infestations -- Arthropod-induced diseases -- Tumors of the epidermis -- Lentigines, nevi, and melanomas -- Tumors of cutaneous appendages -- Tumors and tumor-like proliferations of fibrous and related tissues -- Tumors of fat -- Tumors of muscle, cartilage, and bone -- Neural and neuroendocrine tumors -- Vascular tumors -- Cutaneous metastases -- Cutaneous infiltrates: nonlymphoid -- Cutaneous infiltrates: lymphomatous and leukemic.
- 2010David Weedon ; contributors, Geoffrey Strutton, Adam I. Rubin.An approach to the interpretation of skin biopsies -- Diagnostic clues -- The lichenoid reaction pattern ('interface dermatitis') -- The psoriasiform reaction pattern -- The spongiotic reaction pattern -- The vesiculobullous reaction pattern -- The granulomatous reaction pattern -- The vasculopathic reaction pattern -- Disorders of epidermal maturation and keratinization -- Disorders of pigmentation -- Disorders of collagen -- Disorders of elastic tissue -- Cutaneous mucinoses -- Cutaneous deposits -- Diseases of cutaneous appendages -- Cysts, sinuses, and pits -- Panniculitis -- Metabolic and storage diseases -- Miscellaneous conditions -- Cutaneous drug reactions -- Reactions to physical agents -- Cutaneous infections and infestations - histological patterns -- Bacterial and rickettsial infections -- Spirochetal infections -- Mycoses and algal infections -- Viral diseases -- Protozoal infections -- Marine injuries -- Helminth infestations -- Arthropod-induced diseases -- Tumors of the epidermis -- Lentigines, nevi, and melanomas -- Tumors of cutaneous appendages -- Tumors and tumor-like proliferations of fibrous and related tissues -- Tumors of fat -- Tumors of muscle, cartilage, and bone -- Neural and neuroendocrine tumors -- Vascular tumors -- Cutaneous metastases -- Cutaneous infiltrates - non-lymphoid -- Cutaneous infiltrates - lymphomatous and leukemic.
- 2009. NAPKathleen M. Rasmussen and Ann L. Yaktine, editors ; Committee to Reexamine IOM Pregnancy Weight Guidelines, Food and Nutrition Board and Board on Children, Youth, and Families."As women of childbearing age have become heavier, the trade-off between maternal and child health created by variation in gestational weight gain has become more difficult to reconcile. Weight Gain During Pregnancy responds to the need for a reexamination of the 1990 Institute of Medicine guidelines for weight gain during pregnancy. It builds on the conceptual framework that underscored the 1990 weight gain guidelines and addresses the need to update them through a comprehensive review of the literature and independent analyses of existing databases. The book explores relationships between weight gain during pregnancy and a variety of factors (e.g., the mother's weight and height before pregnancy) and places this in the context of the health of the infant and the mother, presenting specific, updated target ranges for weight gain during pregnancy and guidelines for proper measurement. New features of this book include a specific range of recommended gain for obese women. Weight Gain During Pregnancy is intended to assist practitioners who care for women of childbearing age, policy makers, educators, researchers, and the pregnant women themselves to understand the role of gestational weight gain and to provide them with the tools needed to promote optimal pregnancy outcomes."--Back cover.
- 2012 SpringerCathy Banwell, Dorothy Broom, Anna Davies, Jane Dixon.The Big Australian: Obesity in the Modern World -- An Intergenerational Study Design -- From Habit to Choice: Transformations in Family Dining Over Three Generations -- How Convenience Is Shaping Australian Diets: The Disappearing Dessert -- From Sociable Leisure to Exhaustion: A Tale of Two Revolutions -- Fitness Marginalises Fun and Friendship -- The Rise of Automobility -- The Weight of Time: From Full to Fragmented in 50 Years -- Social Forces Shaping Life Chances and Life Choices -- Restoring Coherence to a Stressed Social System / Cathy Banwell, Dorothy Broom, Anna Davies, Jane Dixon.
- 2011 SpringerSteve Horvath.Networks and fundamental concepts -- Approximately factorizable networks -- Different types of network concepts -- Adjacency functions and their topological effects -- Correlation and gene co-expression networks -- Geometric interpretation of correlation networks using the singular value decomposition -- Constructing networks from matrices -- Clustering procedures and module detection -- Evaluating whether a module is preserved in another network -- Association measures and statistical significance measures -- Structural equation models and directed networks -- Integrated weighted correlation network analysis of mouse liver gene expression data -- Networks based on regression models and prediction methods -- Networks between categorical or discretized numeric variables -- Network based on the joint probability distribution of random varaibles.
- 2017Neil S. Prose, Leonard Kristal.
- 2008Alexander Rae-Grant.
- 2017 ClinicalKeyeditors, Jonathan D. Spratt, Lonie R. Salkowski, Marios Loukas, Tom Turmezei ; consultant editors, Jamie Weir, Peter H. Abrahams.Brain and cranial nerves -- Skull, orbits, paranasal sinuses and face -- Neck -- Vertebral column and spinal cord -- Upper limb -- Breast and axilla -- Thorax: non cardiac -- Thorax: cardiac -- Abdomen and pelvis: cross-sectional -- Abdomen and pelvis: non cross-sectional -- Lower limb -- Functional imaging.
- 2014 ProQuest Ebook CentralRobert C. Hubrecht.The use of legislative and other controls on animal research to meet public expectations and improve animal welfare -- Animal rights and animal welfare : philosophy and science -- Species choice and animal welfare -- The harm/benefit judgement -- Improving the welfare of animals used in research : the 3Rs -- Science and animal welfare : a partnership.
- 2007 Springeredited by Irene Rochlitz.Cat behaviour : social organization, communication, and development / by Sharon L. Crowell-Davis -- The assessment of welfare / by Rachel A. Casey and John W.S. Bradshaw -- The human-cat relationship / by Penny L. Bernstein --Behaviour problems and welfare / by Sarah E. Heath -- Cat overpopulation in the United States / by Philip H. Kass -- The welfare of feral cats / by Margaret R. Slater -- Housing and welfare / by Irene Rochlitz -- Disease and welfare / by Kit Sturgess -- Nutrition and welfare / by Kit Sturgess and Karyl J. Hurley -- Breeding and welfare / by Andreas Steiger.
- 2008 SpringerJeffrey Rushen ... [et al.].Introduction: what is animal welfare? -- Health, disease, and productivity -- Stress and physiological indicators of animal welfare -- Animal behaviour -- Acute or short-term challenges to animal welfare -- Housing for adult cattle -- Housing for growing animals -- Feeding and nutrition -- Stockmanship and the interactions between people and cattle -- Conclusions.
- 2008 Springer[edited by] Cathy M. Dwyer.
- 2015 SpringerXichun Sun.This book represents a daring and rarely attempted endeavor to bridge the gap between histopathology and molecular medicine in that cutting-edge molecular findings are seamlessly integrated into the key morphological features. This volume also includes discussions of short lists of organ-based benign lesions with concerning morphological features. Presented in the differential diagnosis section, they will not only serve as useful checklists for the surgical pathologist who is seriously contemplating a diagnosis of malignancy due to the observation of some cytological or histological atypia, but also help hone the key features of each malignant atypia. Well-Differentiated Malignancies: New Perspectives provides an innovative resource on the difficult topic of well-differentiated malignancies for pathology residents, fellows and for those already in clinical practice.
- Wer Ist's? : Unsere Zeitgenossen : Zeitgenossenlexikon enthaltend Biographien nebst Bibliographien : Angaben über Herkunft, Familie, Lebenslauf, Werke, Lieblingbeschäftigungen, Parteiangehörigkeit, Mitgliedschaft bei Gesselschaften, Adresse. 10 Ausg.1912-35.andere Mitteilungen von allgemeinem Interesse, zusammengestellt und herausgegeben von Herrmann A.L. Degener.
- 2005 Ovideditors, Lewis E. Braverman, Robert D. Utiger.Also available: Print – 2005
- 2013 Ovideditors, Lewis E. Braverman, David S. Cooper."The most comprehensive textbook on the thyroid appears in an extensively revised 10th edition. This classic text provides comprehensive coverage of every aspect of thyroid anatomy, development, biochemistry, physiology, pathophysiology, and treatment of all thyroid disorders. This edition has a more international group of contributors and new chapters on surgical management of thyroid cancer, thyroid disrupters and thyroid hormone analogs. Chapters address clinical controversies regarding subclinical hypothyroidism and hyperthyroidism"--Provided by publisher.
- 2015 Springer Protocolsedited by Biji T. Kurien, R. Hal Scofield.Early days of blotting / Edwin Southern -- Origins of protein blotting / Harry Towbin -- Western blotting : remembrance of things past / W. Neal Burnette -- Simian virus 40 and protein transfer / Jaime Renart -- Western blotting : an introduction / Biji T. Kurien and R. Hal Scofield -- From little helpers to automation / Biji T. Kurien and Harry Towbin -- Spectrophotometric methods to determine protein concentration / J. P. Dean Goldring -- Solubilization of proteins : the importance of lysis buffer choice / Mandy Peach [and three others] -- Simultaneous immunoblotting analysis with activity gel electrophoresis and 2-D gel electrophoresis / Der-Yen Lee and Geen-Dong Chang -- Diffusion blotting : a rapid and simple method for production of multiple blots from a single gel / Ingrid Olsen and Harald G. Wiker -- Multiple immunoblots by passive diffusion of proteins from a single SDS-PAGE gel / Biji T. Kurien and R. Hal Scofield -- Slice blotting / Graeme Lowe -- Localizing proteins by tissue printing / Rafael F. Pont-Lezica -- Dot-immunobinding assay (Dot-Iba) / Sumi Surendran, Annamma Mathai, and Vishnampet Venkataraman Radhakrishnan -- Analysis of antibody clonotype by affinity immunoblotting / Biji T. Kurien and R. Hal Scofield -- Glycosaminoglycan blotting and detection after electrophoresis separation / Nicola Volpi and Francesca Maccari -- Well-based reverse-phase protein array of formalin- fixed paraffin-embedded tissue / Joon-Yong Chung and Stephen M. Hewitt -- Quantitative computerized western blotting in detail / Dalit Talmi-Frank, Charles L. Jaffe, and Gad Baneth -- Cationic electrophoresis and eastern blotting / Engelbert Buxbaum -- Miniaturized blotting system for simultaneous detection of different autoantibodies / Ulrich Canzler [and eight others] -- Proteomic expressional profiling of a paraffin-embedded tissue by multiplex tissue immunoblotting / Joon-Yong Chungand Stephen M. Hewitt -- Post-staining electroblotting for efficient and reliable peptide blotting / Der-Yen Lee and Geen-Dong Chang -- Multistrip western blotting : a tool for comparative quantitative analysis of multiple proteins / Edita Aksamitiene, Jan B. Hoek, and Anatoly Kiyatkin -- Western blotting using PVDF membranes and its downstream applications / Setsuko Komatsu -- Blotting from phastGel to membranes by ultrasound / Joseph Kost and Aharon Azagury -- Western blotting of high and low molecular weight proteins using heat / Biji T. Kurien and R. Hal Scofield -- Membrane strip affinity purification of autoantibodies / Biji T. Kurien -- Strip immunoblotting of multiple antigenic peptides / Biji T. Kurien -- Double-blotting : a solution to the problem of nonspecific binding of secondary antibodies in immunoblotting procedures / Françoise Lasne -- Method for resolution and western blotting of very large proteins using agarose electrophoresis / Marion L. Greaser and Chad M. Warren -- Immunodetection of P-selectin using an antibody to its C-terminal tag / Padmaja Mehta-D'souza -- Improvements and variants of the multiple antigen blot assay-MABA : an immunoenzymatic technique for simultaneous antigen and antibody screening / Oscar Noya [and six others] -- Blotting from immobilized pH gradient gels : application to total cell lysates / Harry Towbin -- Immunoprecipitation : western blot for proteins of low abundance / Edward P. Trieu and Ira N. Targoff -- Native electrophoresis and western blot analysis (NEWeB) : methods and applications / Ioannis N. Manoussopoulos and Mina Tsagris -- Shift-western blotting : separate analysis of protein and DNA from protein-DNA complexes / Matthias Harbers -- Grid-immunoblotting / Olga Yeliosof and R. Hal Scofield -- Detection and quantification of protein-protein interactions by far-western blotting / Joshua A. Jadwin, Bruce J. Mayer, and Kazuya Machida -- Western blot analysis of adhesive interactions under fluid shear conditions : the blot rolling assay / Robert Sackstein and Robert Fuhlbrigge -- Centrifuge blotting / Jinny Paul -- Blotting of coomassie blue-stained proteins from PAGE gels to transparencies / Jinny Paul -- B-cell ELISPOT : for the identification of antigen-specific antibody-secreting cells / Hemangi B. Shah and Kristi A. Koelsch -- T cell ELISPOT : for the identification of specific cytokine-secreting T cells / Kerry M. Leehan and Kristi A. Koelsch -- Membrane microplates for one- and two-color ELISPOT and FLUOROSPOT assays / Alexander E. Kalyuzhny -- SDS-PAGE to immunoblot in one hour / Biji T. Kurien [and three others] -- Single-cell western blotting / Syed M. S. Quadri -- Protein detection by simple western analysis / Valerie M. Harris -- Western blotting using microfluidics / Pothur R. Srinivas -- Two-dimensional gel-based protein standardization verified by western blot analysis / Hisao Haniu [and three others] -- Fingerprint deposition on nitrocellulose and polyvinylidene difluoride membranes using alkaline phosphatase / Biji T. Kurien, Debashish Danda, and R. Hal Scofield -- Other notable protein blotting methods : a brief review / Biji T. Kurien and R. Hal Scofield.
- 2013edited by Janet Greenlees and Linda Bryder.
- 2016John B. West, M.D., Ph.D., D.Sc., Professor of Medicine and Physiology, University of California, San Diego, School of Medicine, La Jolia, California, Andrew M. Luks, M.D., Associate Professor of Medicine, University of Washington, School of Medicine, Seattle, Washington.Structure and function -- Ventilation -- Diffusion -- Blood flow and metabolism -- Ventilation-perfusion relationships -- Gas transport by the blood -- Mechanics of breathing -- Control of ventilation -- Respiratory system under stress -- Tests of pulmonary function.
- 2013Danielle Ofri."By shedding light on how doctors cope with the stresses and responsibilities of patients, colleagues, lawyers, and their personal lives, she explains why it is important that patients know how emotions influence the way physicians treat their patients both medically and interpersonally. Exploring the full range of human emotion--from the fear of making a fatal mistake to the pride and elation of triumphing over death, What Doctors Feel allows patients at the other end of the stethoscope to have a good listen to the beat of the emotional life behind the white coat."--Beacon Press.
- 2015 SpringerRobert B. Taylor.About Medical Writers and Writing -- Getting Started in Medical Writing -- The Process of Medical Writing -- Medical Writing Pointers and Pitfalls -- Getting Your Work in Print -- Ethical Issues in Medical Writing -- Remarkable Medical Writing -- Backstories of Medical Writers and Writing -- What Writers Say about Writing -- A Writer?s Attic -- Web Sites: The Medical Writer?s Guide to the Internet -- Recommended Reading for the Serious Medical Writer.
- 2008 SpringerNenad Markovic, Olivera Markovic.
- Seelig, Tina.
- 2014Jack Tzu-Chieh Wang.Axonal degeneration is a pivotal pathological event in most CNS and PNS diseases, but the molecular mechanisms that control this process remain unclear. Expression of the Wallerian degeneration slow (WldS) transgene robustly delays axon degeneration in various injury models and attenuate disease progression in many neurodegenerative conditions, indicating a common mechanism of axonal self-destruction in traumatic injuries and chronic degenerative events. In this thesis, I examined the mechanism of WldS axon protection as a window to understand the molecular events that orchestrate this axonal self-destruction program. In the first part of my thesis, I demonstrated that continuous, local WldS enzymatic activity in the axon, independent of nuclear gene transcription, is required to confer axonal protection. Furthermore, I showed that injured axons are not immediately committed to degeneration, but rather there is a critical period of 4-5hrs after injury in which the course of degeneration can be reversed. The presence of this latency period before the injured axons irreversibly commit to degeneration suggest that axonal degeneration can be attenuated or halted altogether even long after an injury has occurred. In the second part of the thesis, I investigated the signaling events and mechanisms that are responsible for translating WldS activity into axonal protection. I showed that NAD+, a metabolite of WldS enzymatic activity and a known redox cofactor in the mitochondria, is sufficient and specific to confer WldS-like axon protection. However, WldS axonal protection does not require the axonal mitochondria or involve changes in the bioenergy levels of the axon. I further demonstrated that independently increasing expression of Ca2+ buffering proteins in subcellular compartments is sufficient to delay axonal degeneration, suggesting that enhancement of Ca2+ buffering capacity in axonal subcellular compartments may be one mechanism by which WldS activity or NAD+ confers axonal protection. Finally, comparing the metabolomics profile of WT vs. WldS neurons reveals candidates in mediating NAD+ dependent regulation of intra-axonal Ca2+, and presents potential therapeutic targets to delay axon degeneration. In the third part of my thesis, I investigated the relationship between developmental axonal outgrowth, synaptic targeting and axon regeneration. Using retinal ganglion cells (RGCs) as a model system, I profiled the developmental expression of RGC genes from early embryonic to early postnatal development, a period that was previously shown to trigger a genetic switch to significantly slow the axonal growth rate. In particular, I showed that cyp1b1, a gene implicated in congenital glaucoma, is a potent source of retinoic acid during early RGC development and enhances RGC survival by sustaining retinoic acid production. In addition, several other genes from the expression profiling have been found by others to be involved in axonal regeneration after injury. Together, the findings provide a rich database for understanding the molecular signatures that control the development of retinal ganglion cells, and help uncover genetic factors that regulate axonal growth, targeting and regeneration.
- 2013David Loxterkamp, MD."Primary care has come into the limelight with the passage of the Patient Protection and Affordable Care Act, the unchecked and unsustainable rise in American health care expenditures, and the crest of Baby Boomers who are now Medicare-eligible and entering the most health care-intensive period of their lives. Yet how much is really known about primary care? What Matters in Medicine: Lessons from a Life in Primary Care is a look at the past, present, and future of general practice, which is not only the predecessor to the modern primary care movement, but its foundation. Through memoir and conversation, Dr. David Loxterkamp reflects on the heroes and role models who drew him to family medicine and on his many years in family practice in a rural Maine community, and provides a prescription for change in the way that doctors and patients approach their shared contract for good health and a happy life. This book will be useful to those on both sides of primary care, doctors and patients alike." -- [Publisher-supplied data]
- 2013 ProQuest Ebook CentralLarry R. Churchill, Joseph B. Fanning, and David Schenck.Being a patient is a unique interpersonal experience but it is also a universal human experience. The relationships formed when we are patients can also teach some of life's most important lessons, and these relationships provide a special window into ethics, especially the ethics of healthcare professionals. This book answers two basic questions: As patients see it, what things allow relationships with healthcare providers to become therapeutic? What can this teach us about healthcare ethics? This volume presents detailed descriptions and analyses of 50 interviews with 58 patients, representing a wide spectrum of illnesses and clinician specialties. The authors argue that the structure, rhythm, and horizon of routine patient care are ultimately grounded in patient vulnerability and clinician responsiveness. From the short interview segments, the longer vignettes and the full patient stories presented here emerge the neglected dimensions of healthcare and healthcare ethics. What becomes visible is an ethics of everyday interdependence, with mutual responsibilities that follow from this moral symbiosis. Both professional expressions of healthcare ethics and the field of bioethics need to be informed and reformed by this distinctive, more patient-centered, turn in how we understand both patient care as a whole and the ethics of care more specifically. The final chapters present revised codes of ethics for health professionals, as well as the implications for medical and health professions education.
- 2006 SpringerDan W. Urry.What sustains life? an overview -- The pilgrimage: highlights in our understanding of products and components of living organisms -- Likelihood of life's protein machines: extravagant in construction yet efficient in function -- Consilient mechanisms for diverse protein-based machines: the efficient comprehensive hydrophobic effect -- On the evolution of protein-based machines: toward complexity of structure and diversity of function -- Biology thrives near a movable cusp of insolubility -- Consilient mechanisms for the protein-based machines of biology -- Advanced materials for the future: protein-based materials with potential to sustain individual health and societal development -- Appendix 1. Mechanics of elastin: molecular mechanism of biological elasticity and its relationship to contraction / Dan W. Urry and Timothy M. Parker -- Appendix 2. Development of elastic protein-based polymers as materials for acoustic absorption / Dan W. Urry... [et al.]
- 2007 SpringerAlan V. Parbhoo.
- What's new in surgical oncology : a guide for surgeons in training and medical/radiation oncologists2013 SpringerAndrea Valeri, Carlo Bergamini, Ferdinando Agresta, Jacopo Martellucci, editors.The purpose of this book is twofold: First, it provides an up-to-date overview of the field of surgical oncology for surgeons in training. Particular attention is devoted to the principles of surgery, but important aspects of radiation and medical oncology are also discussed. Furthermore, diagnostic, staging, and treatment algorithms are presented that will offer invaluable assistance in management decision making. The second aim of the book is to offer a comprehensive reference source on the role of surgery in curative and palliative management for medical and radiation oncologists (in practice and in training) and other healthcare professionals involved in the care of cancer patients. The full range of cancer types is covered in a practical, multidisciplinary approach, and additional chapters are devoted to pediatric malignancies, the role of new surgical technologies, and surgical emergencies.
- 2013 OSOAbigail Saguy.This study presents each of the various ways in which fat is understood in America today, examining the implications of understanding fatness as a health risk, disease, and epidemic, and revealing why we have come to understand the issue in these terms, despite considerable scientific uncertainty and debate.
- 2011 ClinicalKey[edited by] Barbara Young, William Stewart, and Geraldine O'Dowd.Cellular responses to injury -- Acute inflammation, healing and repair -- Chronic inflammation -- Infections of histological importance -- Amyloidosis -- Disorders of growth -- Dysplasia and neoplasia -- Atherosclerosis -- Thrombosis and embolism -- Infarction -- Cardiovascular system -- Respiratory system -- Gastrointestinal system -- Liver and pancreaticobiliary system -- Urinary system -- Lymphoid and haematopoietic systems -- Female reproductive system -- Breast -- Male reproductive system -- Endocrine system -- Skin -- Bone and soft tissues -- Nervous system.Also available: Print – 2011
- 2014 ClinicalKeyBarbara Young, Geraldine O'Dowd, Phillip Woodford.Take a simple approach to understanding the fundamentals with Wheater's Functional Histology. Offering concise text accompanied by hundreds of captions and images of histology slides, this best-selling textbook will equip you with all the must-know histology information you need to complete your courses and ace your exams. Recognize the microscopic structure of normal human tissues and how it relates to function with the help of over 900 high-quality histology images and illustrations.Master how to apply histology in a clinical context through coverage of common clinical conditions in each chapter.Access the entire contents online at Student Consult, including all of the images, a virtual histolab, and USMLE-style self-assessment questions and rationales.
- 2016Paul Kalanithi ; foreword by Abraham Verghese.On the verge of completing a decade's worth of training as a neurosurgeon, Kalanithi was diagnosed with stage IV lung cancer. Just like that, the future he and his wife had imagined evaporated. Kalanithi chronicles his transformation from a naïve medical student into a neurosurgeon at Stanford working in the brain, the most critical place for human identity, and finally into a patient and new father confronting his own mortality.
- 2008Robert Klitzman."Magic white coats": forms of denial and other internal obstacles to becoming a patient -- "The medical self": self-doctoring and choosing doctors -- "Screw-ups" in the system and in care: external obstacles faced in becoming patients -- "They treated me as if I were dead": peripheralization and discrimination -- "Coming out" as patients: disclosures of illness -- Double lens: contrasting views and uses of medical knowledge -- "Being 'strong'": workaholism, burnout, and coping -- "Once a doctor, always a doctor?": retirement -- "Touched by the light": spiritual beliefs and their obstacles -- Us vs. them: treating patients differently -- Improving education: can empathy be taught? -- Conclusions: the professional self. "Magic white coats": forms of denial and other internal obstacles to becoming a patient -- "The medical self": self-doctoring and choosing doctors -- "Screw-ups": external obstacles faced in becoming patients -- "They treated me as if I were dead": peripheralization and discrimination -- "Coming out" as patients: disclosures of illness -- Double lens: contrasting views and uses of medical knowledge -- "Being 'strong'": workaholism, burnout, and coping -- "Once a doctor, always a doctor?": retirement -- "Touched by the light": spiritual beliefs and their obstacles -- Us vs. them: treating patients differently -- Improving education: can empathy be taught? -- Conclusions: the professional self.
- 2010 SpringerJoshua A. Perper, Stephen J. Cina.Part 1. Ethics and the Physician -- In the Beginning -- Perfect Intentions, Imperfect People -- Part 2. When Doctors Kill -- The Alpha Killers: Three Prolific Murderous Doctors -- America's Contribution to Medical Mayhem -- International Men of Mystery: Other Medical Murderers -- To Catch a Killer: Investigating Serial Murders -- The Nazi Murders -- Part 3. In the Name of Science -- Hitler's “Scientists” -- Made in Japan: Unethical Experiments -- Good Old Fashioned American Ingenuity - and Evil -- Physician Kill Thyself: The Story of Dr. Gwinn E. Puig -- Part 4. Politics and Medicine -- Libel Plots Against Physicians (Who Killed Dr. Zhivago?) -- Judge, Jury, Executioner, and Doctor -- Trading Treatment for Terror -- Guilty Until Proven Innocent -- Part 5. What Now? -- Euthanasia, and Assisted Suicide: What Would Hippocrates Do? -- Malpractice or Murder? -- It's All Natural! -- Contagious Caregivers -- Fictitious Physicians: Where Has Marcus Welby Gone? -- Doctors to the Stars.
- 2011Manwai Candy Ku.In this dissertation, I investigate when and why gender segregation occurs in the professions of medicine, law and teaching. Drawing on social psychological perspectives on gender and theories on career development, I posit that segregation patterns differ across these three occupational contexts due to differences in gender valence of jobs and structures of career process. Specifically, I argue that early career choices are more gender-segregated in the highly gendered context of medicine and teaching, while the extent of gender segregation may vary (and increase) more substantially over time in the less structured contexts of teaching and law. Using data from professional organizations and government sources, I analyzed careers of a cohort of doctors, lawyers and teachers from their entry into their professions in 1991-1994 to 10-17 years after entry. Consistent with my hypotheses, doctors and teachers displayed highly gender-different aspirations than lawyers, and whereas the level of gender segregation remained fairly constant for doctors, it fluctuated somewhat for teachers and increased substantially for lawyers, particularly after the first six years of work. Analysis of 39 in-depth interviews further suggests that job choices among doctors and teachers reflect deeply held gendered ideas about people and work, whereas job choices among lawyers are seen as series of adjustments to organizational contexts, adjustments that usually differ for women and men. In total, these findings make the case for a more detailed view of intra-occupational gender segregation, one that places gender processes within the occupational context. In proposing a context-driven paradigm for studying gender inequality, this study brings the occupation to the center of the investigation, and argues for a more expansive view of gender segregation that takes into account the meanings and structures that delineate career decision-making and the constraints on the process.
- 2007 SpringerLola Romanucci-Ross and Laurence Tancredi.
- 2013Everaldo Montealegre.In this dissertation I provide an empirically based account of the trajectory of right-to-health litigation in Colombia during the past twenty years (1991-2012). Focusing on several critical junctures of this trajectory and drawing from the results of multi sited fieldwork, I reconstruct how a set of stakeholders (policymakers, judges, litigants, activists and pharmaceutical companies) spurred the surge of right-to-health litigation in Colombia, which according to recent estimates is the highest among middle-income countries. Additionally, I explore how a set of structural judicial remedies handed down by the Colombian Constitutional Court in 2008--ruling T-760/08--addressed the institutional determinants of the surge of right-to-health litigation and nudged policymakers in the direction of health-care reform.
- 2007 Springeredited by Ora H. Pescovitz, Emily C. Walvoord.
- 2010by David Werner ; with Carol Thuman, Jane Maxwell, and Andrew Pearson ; with drawings by the author and by Felicity Cary.
- 1992/2010by David Werner with Carol Thuman and Jane Maxwell ; with drawings by David Werner.
- 2012 ScienceDirectMeridel I. Gatterman.Providing a balanced, evidence-based discussion of whiplash and its associated disorders, Whiplash: A Patient Centered Approach to Management compiles information from many sources into a single, definitive reference. It clearly delineates rationales and procedures, covering cervical spine anatomy, neurology, kinesiology, epidemiology, patient history and assessment, imaging, soft tissue injuries, articular lesions, rehabilitation, and prognosis. Using numerous full-color photos and illustrations, an expert author team led by Dr. Meridel Gatterman offers concrete guidelines for a patient-centered approach to care of whiplash and whiplash-related conditions -- one that recommends minimally invasive procedures and therapies whenever possible. A companion Evolve website includes video clips showing stretching exercises, printable patient handouts, and narrated PowerPoint slides. A patient-centered approach to care emphasizes working with patients as partners, with both preferring minimally invasive procedures and therapies where appropriate, in a way that promotes self-healing, a holistic approach to the patient, and a humanistic attitude with regard to the patient/practitioner relationship. An easy-to-follow organization helps you to clearly identify whiplash and plan a course of treatment, beginning with an in-depth description of whiplash and the various approaches to treatment and moving on to cover the anatomy of the cervical spine, the mechanism of injury, physical examination, and imaging, then continuing with the management of whiplash injuries and complications such as headaches and joint injuries. Full-color photos and illustrations clarify concepts and procedures. Evidence-based content is based on findings in current literature, and cited in chapter references. Coverage of both typical and less common types of whiplash injuries helps you accurately assess varied symptoms and avoid overlooking any related signs and symptoms. Detailed coverage of the relationship between the cervical spine and the cervical distribution of the autonomic nervous system helps you recognize the potential complications of whiplash and how nerve anatomy informs these complications. More than 20 tables and charts provide a quick reference to facilitate review of the material. A glossary provides definitions and pronunciations of terms related to whiplash. Expert author Meridel Gatterman, MA, DC, MEd, is one of the leading chiropractic academics in the U.S., has written several other chiropractic textbooks and many peer-reviewed journal articles, has served as both a Dean and Director for two different chiropractic schools, and currently acts as a Consultant to the Oregon Board of Chiropractic Examiners. A companion Evolve website includes video clips of a chiropractor performing stretching exercises, plus an image collection, narrated PowerPoint slides, and printable patient handouts.
- 2014 SpringerDario Carlo Alpini, Guido Brugnoni, Antonio Cesarani, editors.The new edition of this book provides an up-to-date and comprehensive overview of whiplash-associated disorders, focusing in particular on a functional approach to clinical and instrumental diagnosis and rehabilitative treatment. It fully reflects the changes in our understanding of whiplash injuries since the first edition, and in particular the increased awareness that whiplash is a whole-body trauma in which forces act progressively from the lumbar region to the brain, through the cervical spine. Detailed attention is paid to the functional connections between the sense organs of the inner ear, the sympathetic system, and the spine with a view to optimizing diagnosis and treatment. It is explained how various treatment options can be employed to best effect in patients with different symptoms, following, but updating, the well-known Quebec Task Force guidelines. Underestimated aspects such as positional vertigo, somatic tinnitus, temporomandibular disorders, and back pain are also considered. This book will be an invaluable tool in everyday clinical practice for all who are involved in the diagnosis and treatment of whiplash injury.
- 2012 SpringerAndreas Otte.In the past two decades much has been published on whiplash injury, yet both the confusion regarding the condition and the medicolegal discussion surrounding it have increased. In this scenario, a guide to recent and current international research in the field is more necessary than ever. Especially functional imaging methods â" such as single-photon emission tomography, positron emission tomography, functional MRI, and hybrid techniques â" have demonstrated a variety of significant brain alterations. This book accordingly offers a critical approach to the challenging interpretation of the new research data obtained using functional neuroimaging in whiplash injury. It covers all aspects, including the imaging tools themselves and the different methods of image analysis. Whiplash Injury: New Methods of Functional Neuroimaging will hopefully help patients, their relatives and friends, physicians, and others to understand this condition as a disease.
- 2015 SpringerGiuseppe Mancia, Guido Grassi, Gianfranco Parati, Alberto Zanchetti.This book addresses all aspects of white coat hypertension? the phenomenon of raised blood pressure in a medical setting yet not elsewhere? from its history to its pathophysiology, diagnosis and treatment. White coat hypertension is a common condition, accounting for 30?40% of the overall hypertensive population. While many studies have addressed this condition, controversy still exists over whether it causes an increased risk to sufferers and should be treated. In the volume neurogenic and non-neurogenic mechanisms are discussed and the significance of various predictive factors, evaluated. The association of white coat hypertension with dysmetabolic risk factors, new-onset diabetes and other conditions is carefully reviewed. Further chapters consider the occurrence of asymptomatic organ damage and cardiovascular outcomes in affected patients, and helpful guidance is also provided on the controversial issue of when to treat and when not to treat. White Coat Hypertension is based largely on work done during the past 30 years by renowned researchers working in Milan, who have made key contributions in improving knowledge of the condition and whose work is well known across the world.
- 2008 SpringerRobert B. Taylor.Pt. 1. Heroes, diseases and remedies. Heroes in medical history -- Diseases that changed history -- Drugs and other remedies -- pt. 2. The heritage and culture of medicine. Medical words and phrases -- Whose syndrome? Stories of medical eponyms -- Medical abbreviations, acronyms, euphemisms, jargon, and slang -- Medical aphorisms -- Memorable medical quotations -- pt. 3. Clinical notes and medical misadventures. Famous persons as patients -- Misadventures: myths, misinformation, blunders, and wrongdoing -- Now and future practice.
- 2014 SpringerSelva Baltan, S. Thomas Carmichael, Carlos Matute, Guohua Xi, John H Zhang, editors.The first book to provide a systematic expert summary of normal white matter morphology as well as white matter injury following stroke and other CNS injuries. White matter injury can result from both ischemic and hemorrhagic stroke as well as a host of other CNS diseases and conditions such as neonatal injuries, neurodegenerative disorders including Alzheimer's disease, traumatic brain injuries, carbon monoxide poisoning, and drug or alcohol overdoses. The extent of white matter injury is extremely important to patient outcomes. Several recent technological developments including advanced neuroimaging and the breeding of new rodent models of white matter injury have provided growing insight into initial damage and repair after a stroke or other damaging event.
- Wages and hours in private hospitals, California, 1958 — White matter injury in stroke and CNS disease (100)
- WHO application of ICD-10 to deaths during pregnancy, childbirth and puerperium : IDC MM. — World malaria report 2015 (100)
- World malaria report 2008 — Wyllie's Treatment of epilepsy : principles and practice. Sixth edition [6th ed.]. (30)
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