Books

Contents:
1. History of Botulinum Toxin for medical and aesthetic use
2. Anatomy and aesthetic principles
3. Botulinum Toxin: from molecule to medicine
4. Myobloc
5. Abobotulinumtoxin: development and aesthetic usage
6. IncobotulinumtoxinA (Xeomin/Bocouture)
7. Future injectable toxins
8. Reconstitution, dilution, diffusion, and migration of Botulinum Toxin
9. Patient selection
10. Treatment of the glabella
11. Treatment of the forehead
12. Treatment of the periocular area - Crow's feet, brow and bunny lines
13. Contouring of the lower face and of the lower leg and calf
14. Treatment of the perioral area
15. Neck rejuvenation
16. Correction of facial asymmetry
17. Complications and diffusion
18. Combination therapy of Botuliinum Toxin with other nonsurgical procedures
19. Peri-procedure Botulinum Toxin for skin cancer patients and scars
20. Achieving a natural look
21. Special considerations in darker skin
22. Axillary hyperhidrosis
23. Primary focal palm, sole, craniofacial, and compensatory hyperhidrosis
24. Topical Botulinum Toxin
25. Exciting new uses of Botulinum Toxin Type A: dermatology/dermatologic surgery and beyond
26. Modulating affect and mood with Botulinum Toxin injections: psychosocial implications of neuromodulators
27. Onabotulinumtoxin A (Botox) in dermatology
Index.

Contents:
A century of brachytherapy (from the prostate's perspective) / Jesse N. Aronowitz
Radiobiologic concepts for brachytherapy / Alexandra J. Stewart, Robert A. Cormack, and Kathryn D. Held
Technical aspects of brachytherapy / Mandar S. Bhagwat, Ivan M. Buzurovic, Antonio L. Damato, Scott A. Friesen, Jorgen L. Hansen, Desmond A. O'Farrell, Emily Sugar, and Robert A. Cormack
Genitourinary brachytherapy / Paul L. Nguyen, André-Guy Martin, and Peter F. Orio
Gynecologic brachytherapy / Larissa J. Lee, Antonio L. Damato, and Akila N. Viswanathan
Breast brachytherapy / Simona M. Shaitelman, Chirag Shah, Leonard H. Kim, Frank A. Vicini, Douglas W. Arthur, and Atif J. Khan
Thoracic brachytherapy / Keyur J. Mehta, Nitika Thawani, and Subhakar Mutyala
Skin brachytherapy / Phillip M. Devlin and Anna O. Likhacheva
Head and neck brachytherapy / J. Nicholas Lukens, Kenneth S. Hu, Peter C. Levendag, David Teguh, Paul Busse, and Louis B. Harrison
Central nervous system brachytherapy / Abigail L. Stockham and Nils D. Arvold
Gastrointestinal brachytherapy / Alexandra J. Stewart, Nikolaos Tselis, Michele Albert, Nitika Thawani, and Arthur Sun Myint
Soft tissue sarcoma brachytherapy / Caroline L. Holloway and Chandrajit P. Raut
Pediatric brachytherapy / Lara Hathout, Suzanne L. Wolden, and Gilad N. Cohen
Vascular brachytherapy / Chien Peter Chen, Ray Lin, and Prabhakar Tripuraneni
Foundations of a brachytherapy practice / D. Jeffrey Demanes, Ron DiGiaimo, Casilda Menchaca-Garcia, and Tamara Syverson.

Summary: "Thoroughly updated to reflect the latest advances and technologies, Braddom's Physical Medicine and Rehabilitation, 6th Edition, remains the market leader in the field of PM&R. For more than 20 years, this bestselling reference has been the go-to resource for the entire rehabilitation team, providing in-depth coverage of essential core principles along with the latest research, technologies, and procedures that enhance patient care and facilitate optimal return to function. In this edition, lead editor Dr. David X. Cifu and his team of expert associate editors and contributing authors employ a more succinct format that emphasizes need-to-know material, incorporating new key summary features, including high-yield information and study sheets for problem-based learning"--Publisher's description.

Contents:
The physiatric history and physical examination
Examination of the pediatric patient
Rehabilitation of swallowing disorders
Psychological assessment and intervention in rehabilitation
Practical aspects of impairment rating and disability determination
Occupational medicine and vocational rehabilitation
Quality and outcome measures for medical rehabilitation
Electrodiagnostic medicine
Rehabilitation and prosthetic restoration in upper limb amputation
Lower limb amputation and gait
Upper limb orthotic devices
Lower limb orthoses
Spinal orthoses
Wheelchairs and seating systems
Therapeutic exercise
Manipulation, traction, and massage
Physical agent modalities
Integrative medicine in rehabilitation
Assistive technology and environmental control devices
Neurogenic lower urinary tract dysfunction
Neurogenic bowel : dysfunction and rehabilitation
Sexual dysfunction and disability
Spasticity
Prevention and management of chronic wounds
Vascular diseases
Burns
Acute medical conditions: cardiopulmonary disease, medical frailty, and renal failure
Chronic medical conditions: : pulmonary disease, organ transplantation, and diabetes
Cancer rehabilitation
Geriatrics
Rheumatologic rehabilitation
Common neck problems
Low back disorders
Osteoporosis
Upper limb pain and dysfunction
Lower limb pain and dysfunction a
Chronic pain
Pelvic floor disorders
Sports medicine and adaptive sports
Motor neuron diseases
Neuropathies
Myopathic disorders
Traumatic brain injury
Stroke rehabilitation
Degenerative movement disorders of the central nervous system
Multiple sclerosis
Cerebral palsy
Myelomeningocele and other spinal dysraphisms
Spinal cord injury
Auditory, vestibular, and visual impairments.

Summary: Concise and portable, Braddom's Clinical Handbook of Physical Medicine and Rehabilitation, by Drs. David X. Cifu and Henry L. Lew, gives you dependable, up-to-date content in a handbook format ideally suited for use at the bedside or in outpatient clinics. This quick reference covers the everyday topics you need - assistive devices and orthoses, spasticity, pediatric, adult, and geriatric care, pain management, outcome measures, and much more - all derived from the most trusted name in the field of PM&R.

Summary: "Although musculoskeletal injuries are by far the most common injuries seen in sports, neurological injuries are often the most serious and potentially devastating. The Brain, Spine and Nerves in Sports is a comprehensive textbook edited by neurosurgeons Nicholas Theodore and Russell R. Lonser, internationally renowned experts in sports-related brain and spine trauma. The book covers intricacies associated with the diagnosis and treatment of sports-related neurological injuries, with firsthand, collaborative insights from a who's who of multidisciplinary neurological experts in sports injury medicine. The book is organized into three sections and 40 thoughtfully curated chapters covering diagnosis, surgical and nonsurgical approaches, and management of traumatic brain injuries, concussions, spinal cord injuries, and peripheral nerve injuries. The final chapter focuses on leveraging concussion data to improve the safety of American football. Each chapter blends theoretical knowledge, evidence-based practices, case studies, and practical insights derived from the authors' extensive clinical experience"-- Provided by publisher.

Summary: This book analyzes and discusses in detail art therapy, a specific tool used to sustain health in affective developments, rehabilitation, motor skills and cognitive functions. Art therapy is based on the assumption that the process of making art (music, dance, painting) sparks emotions and enhances brain activity. Art therapy is used to encourage personal growth, facilitate particular brain areas or activity patterns, and improve neural connectivity. Treating neurological diseases using artistic strategies offers us a unique option for engaging brain structural networks that enhance the brain's ability to form new connections. Based on brain plasticity, art therapy has the potential to increase our repertoire for treating neurological diseases. Neural substrates are the basis of complex emotions relative to art experiences, and involve a widespread activation of cognitive and motor systems. Accordingly, art therapy has the capacity to modulate behavior, cognition, attention and movement. In this context, art therapy can offer effective tools for improving general well-being, quality of life and motivation in connection with neurological diseases. The book discusses art therapy as a potential group of techniques for the treatment of neurological disturbances and approaches the relationship between humanistic disciplines and neurology from a holistic perspective, reflecting the growing interest in this interconnection.

Contents:
Foreword
Preface
Introduction
Is there an artistic treatment for neurological diseases?
Biology of art
The beauty and the brain: Neuroaesthetics
Neurodegenerative diseases and changes in artistic expression
Painting in neurology
Illusions in neurology: from phantoms to mirror therapies
Music and Mirror Neurons
Opera and Neurology
Cinema and Neurology, from history to therapy
Dance therapy: a clinical approach
Literature and neurology: Marcel Proust and Hermann Von Helmholtz
Ceroplastic and neurology
The significance of art therapy.

Summary: "Now in its fourth edition, The Brain and Behavior introduces the field of neurobiology of human behavior to a wide audience, from graduate students to professionals in the fields of psychology, psychiatry and neurology. This comprehensive resource focuses on locating human behaviors to specific regions of the brain, aiming to make a complex topic visually accessible through the inclusion of clear and focused illustrations. This important new edition emphasises recent developments in our understanding of the human brain which have emerged from imaging studies. The text also features patient case histories with documented anatomical evidence, tying the science with actual clinical examples, making it the most accessible book for medical practitioners of all levels. The collaboration between a neuropsychiatrist, a behavioral neurologist and a neuroanatomist has resulted in a book which synthesizes the complex and evolving information on the neurobiology of human behavior, and presents it in an eminently readable volume"--Publisher's description.

Contents:
Introduction
Anatomy of the gross brain
Histology
Occipital and parietal lobes
Temporal lobe: neocortical structures
Frontal lobe
Basal ganglia
Diencephalon: hypothalamus and epithalamus
Diencephalon: thalamus
Brainstem
Limbic system: temporal lobe
Limbic system: cingulate cortex
Asymmetry and interhemispheric connections.

Summary: This book discusses the underlying mechanisms connecting the brain and heart. The physiology of the brain is such that it is easily affected by any altered physiology of other systems, which in turn may compromise cerebral blood flow and oxygenation. Together, the brain and heart control our body systems, allowing them to function automatically. This interaction between the brain and other systems makes it important for us to understand how any kind of injury to the brain can produce complications in remote organs or systems, such as the heart. The central nervous system is responsible for vegetative function and is central to homeostasis. Further, central nervous system responses are linked to the ongoing function of other organ systems e.g. feeding, thermoregulation, reproduction and muscle activity. It is therefore logical that neural control of the cardiovascular system must also interact with the neural control of other organ systems. This book explains in detail stressed cardiac conditions, discussing the pathophysiology and proposed treatment, and also describing lesser-known crosstalks between the acutely or chronically affected brain and heart.

Contents:
Intro
Preface
Acknowledgement
Contents
About the Editors
Chapter 1: Neurophysiology of Heart
1.1 Basic Architecture of Cardiac Control
1.2 Neural Substrate for Control of Heart
1.2.1 C1 Neurons of Ventrolateral Medulla (VLM)
1.2.2 Nucleus Ambiguus (NA)
1.2.3 Nucleus Tractus Solitarius (NTS)
1.3 Innervation of the Human Heart
1.3.1 Afferents from the Heart
1.3.2 Efferents to the Heart
1.3.3 Cardiac Plexus
1.3.4 Intrinsic Cardiac Nervous System
1.4 Effect of Sympathetic and Parasympathetic Drive on Heart 1.4.1 Laterality in the Autonomic Control of the Heart
1.4.2 Reciprocal Antagonism
1.4.3 Synergistic Co-activation
1.4.4 Sequential Activation
1.4.5 Context Specific Co-activation
1.5 Neural Organization for Cardiovascular Control
References
Chapter 2: Physiology of Cardiovascular System
2.1 Haemodynamics of Cardiovascular System
2.1.1 Evolutionary Origins of Design of Cardiovascular System
2.1.1.1 Teleology
2.1.2 Pressures and Volumes of Heart and Vasculature
2.1.2.1 Mean Circulatory Filling Pressure
2.1.2.2 Stressed and Unstressed Blood Volume 2.1.2.3 Factors Affecting Mean Circulatory Filling Pressure
2.1.2.4 Effect of Pulsatile Activity of Heart
2.1.3 Heart as a Pump
2.1.3.1 Heterometric Autoregulation (Frank-Starling's Law of Heart)
2.1.3.2 Homeometric Autoregulation
2.1.3.2.1 Anrep Effect (Effect of Sudden Changes in the Aortic Pressure)
2.1.3.2.2 Bowditch Effect (Effect of Sudden Change in the Heart Rate)
2.1.3.3 Importance of Heterometric and Homeometric Autoregulation
2.1.3.4 Effect of Neural Stimulation on Heart
2.1.3.5 Cardiac Cycle
2.1.3.5.1 Left Ventricular Systole 2.1.3.5.2 Left Ventricular Diastole
2.1.3.6 Ventricular Function Curve
2.1.3.7 Pressure-Volume Curves of Ventricles
2.1.3.8 Cardiac Energetics
2.1.4 Vasculature
2.1.4.1 Effect of Resistance on Pressure Gradient in Vasculature
2.1.4.2 Distribution of Cardiac Output
2.1.5 Cardiac Output
2.1.5.1 Effect of Change in Resistance on Cardiac Output
2.1.5.2 Matching Cardiac Output with Oxygen Demand
2.1.5.3 Cardiac Output as Point of Circulatory Equilibrium
2.1.5.3.1 Venous Return Curve
2.1.5.3.2 Cardiac Response Curve
2.1.5.3.3 Circulatory Equilibrium 2.1.6 Assessment of Pump Function of Heart
2.2 Cardiac Reflexes
2.2.1 Afferent and Efferent Pathways for Cardiac Reflexes
2.2.2 Reflexes Originating from the Baroreceptors
2.2.2.1 Neural Mechanism of Baroreflex
2.2.2.2 Quantification of Baroreflex Sensitivity
2.2.2.3 Normal Values of Baroreflex Sensitivity
2.2.2.4 Factors Affecting Baroreflex Sensitivity
2.2.2.5 Baroreflex Sensitivity in Diseases
2.2.2.6 Role of Baroreflex in Short-Term and Long-Term Regulation of the Blood Pressure
2.2.3 Reflexes from Atria
2.2.3.1 Neural Mechanism of Atria Reflexes

Summary: Back Cover Text. This ambitious and comprehensive manual represents an essential contribution to our current understanding of interactions between heart and brain, a research topic generating growing interest. Despite the increasing awareness that neural mechanisms are the primary cause of cardiac disease and its progression, therapy continues to focus on end-organ protection and does not approach the neural core of the problem. Growing public health problems such as heart failure are still treated with autonomic drugs that are 30-40 years old and simply act on cardiac receptors. However, it has now been shown that the progression of ischemic heart disease to heart failure is mainly due to abnormal central responses to incipient cardiac disease, with neural activation the primary cause rather than the consequence of cardiac remodeling. Written by leading international experts in their respective research areas, it presents a variety of perspectives on the core topic: from social and philosophical to gender-related aspects. Designed for a broad readership, it includes dedicated sections for cardiologists, psychiatrists, neurologists and psychotherapists looking for a more insightful and targeted approach to neuro-cardiovascular disease.

Contents:
Intro
Preface
Acknowledgments
Contents
About the Editors
About the Section Ediotrs
Contributors
Part I: Functional Anatomy and Molecular Basis of the Cardiac-Brain Axis
1 Brain-Heart Afferent-Efferent Traffic
Introduction: Overview of Cardiac Neuronal Control
Structural and Functional Organization of the Cardiac Nervous System: Peripheral Signaling
Cardiac Afferent Neurons
Nodose Ganglion Cardiac Afferent Neurons
Dorsal Root Ganglion Cardiac Afferent Neurons Cardiovascular Afferent Neurons in Intrathoracic Extracardiac Ganglia and in Ganglionated Plexi
Cardiac Motor Neurons
Cardiac Sympathetic Efferent Neurons
Cardiac Parasympathetic Efferent Neurons
Local Circuit Neurons
Structural and Functional Organization of the Cardiac Nervous System: Central Signaling
Neuraxial Transduction of Cardiac Pathology
Neuraxial Transduction of Myocardial Ischemia and Infarction
Neuraxial Transduction in Heart Failure
Concluding Summary
Cross-References
References
2 Brain-Heart Communication
Introduction Evidence of Heart-Brain Interactions: The Hardware
The Signaling Pathways: The Software
Reflexes and Modulators: A Complex Network Affecting Cardiac Function
The Baroreceptor Reflex
Adrenaline
Angiotensin II
Natriuretic Peptides
Neurotrophins
Conclusions
Cross-References
References
3 The Cardiorenal Cross Talk
Introduction
Measurements of Autonomic Nervous System Activity
Sympathetic Innervation of the Kidney
The Sympathorenal Axis in Heart Failure Consequences of Neurohormonal Axis Activation and Fluid Retention in the Circulatory System, in the Kidney Function, and in th...
Conclusion
References
4 Genetic Determinants Affecting the Relationship Between the Autonomic Nervous System and Sudden Death
Introduction
Neurocardiac Interactions and Ventricular Arrhythmogenesis
Anatomy
Physiology
Role in Ventricular Arrhythmogenesis
Genetic Determinants of Autonomic Nervous System Remodeling
Altered Innervation
Variants in Human Adrenergic Receptors
Altered Autonomic Nervous System in Neuronal Disease Sudden Infant Death Syndrome
Sudden Unexpected Death in Epilepsy
Small Fiber Neuropathy
Genetic Determinants of Inherited Arrhythmia Syndromes Susceptible to Autonomic Nervous System Triggering
Long QT Syndrome
Catecholaminergic Polymorphic Ventricular Tachycardia
Brugada Syndrome
Takotsubo Cardiomyopathy
Sudden Cardiac Death in General Population
Conclusion
References
5 Cognitive Decline in Elderly Patients with Hypertensive Heart Disease
Introduction
Hypertension and Hypertensive Heart Disease in the Elderly

Summary: The 41st Annual International Conference of the IEEE EMBS, took place between July 23 and 27, 2019, in Berlin, Germany. The focus was on "Biomedical engineering ranging from wellness to intensive care." This conference provided an opportunity for researchers from academia and industry to discuss a variety of topics relevant to EMBS and hosted the 4th Annual Invited Session on Computational Human Models. At this session, a bevy of research related to the development of human phantoms was presented, together with a substantial variety of practical applications explored through simulation.

Contents:
Introduction
Tumor Treating Fields Dosimetry and Treatment Planning
A Theory of Mechanisms Underlying 200 kHz AC Electric Fields Effects on Tumor Cell Structures
A thermal study of Tumor Treating Fields for glioblastoma therapy
Improving Tumor Treating Fields with Skull Remodeling Surgery. Surgery Planning and Treatment Evaluation with Finite Element Methods
A Computational FEM Parcelled-Brain Model for Electric Field Analysis in Transcranial Direct Current Stimulation
Computer Model of Electroconvulsive Therapy with Tractography Analysis
Personalization of multi-electrode setups in tCS: methods and advantages
Solving High-Resolution Forward Problems for Extra- and Intracranial Neurophysiological Recordings Using Boundary Element Fast Multipole Method
Modeling Primary Fields of TMS Coils with the Fast Multipole Method
Functional Requirements of Small- and Large-Scale Neural Circuitry Connectome Models
A miniaturized ultra-focal magnetic stimulator and its preliminary application to the peripheral nervous system
Modelling studies of non-invasive electric and magnetic stimulation of the spinal cord
Simplifying the Numerical Human Model with k-means Clustering Method
Using Anatomical Human Body Model for FEM SAR Simulation of a 3T MRI System
RF-Induced Unintended Stimulation for Implantable Medical Devices in MRI.

Summary: This book discusses normal brain physiology and renal physiology, as well as the interactions between the two. The physiology of the brain can easily be affected by any changes to the physiology of other systems, which in turn may compromise cerebral blood flow and oxygenation. Together the brain and the renal system help our body systems to function automatically. The book addresses the basic aspects of neurophysiology and renal physiology in three broad sections, the first of which covers the basic principles of cerebral physiology and neural regulation of the renal system. The second part reviews the normal physiology of the renal system, including the mechanism of action, while the last section summarizes the correlation between the brain and kidney. Highly informative and clearly structured, the book provides essential insights for anyone with an interest in physiology and medicine.

Contents:
Intro
Preface
Acknowledgement
Contents
About the Editors
1: Neurophysiology and Renal System
1.1 Basics of Cerebral Physiology
1.1.1 Cerebral Blood Flow and Autoregulation
1.1.1.1 Cerebral Blood Flow
1.1.1.2 Cerebral Autoregulation
1.1.2 Blood Cerebrospinal Fluid and Blood-Brain Barrier
1.1.3 Role of Brain in Body Fluid Dynamics
1.2 Neural Regulation of Renal System
1.2.1 Efferent Signals from Central Nervous System to Kidneys
1.2.1.1 Neural Control of the Renal Circulation
1.2.1.2 Neural Control of Renal Tubular Function 1.2.1.3 Neural Control of Renal Hormonal Secretion
1.2.2 Afferent Signals from Kidneys to Central Nervous System
1.2.2.1 Renorenal Reflex Control of Renal Function
1.2.2.2 Mechanisms of Activation of Renal Sensory Nerves
1.3 Role of Renal Sympathetic Nerves in Pathophysiological States
1.3.1 Hypertension
1.3.2 Chronic Sodium-Retaining Edema-Forming States
1.4 Brain-Gut-Kidney Axis
1.5 Conclusion
References
2: Normal Physiology of Renal System
2.1 Structure and Function of Kidney
2.1.1 Gross Structure
2.1.1.1 Location 2.1.1.2 Cortex and Medulla
2.1.2 Functional Unit: The Nephron
2.1.2.1 Renal Corpuscle
2.1.2.2 Renal Tubule
2.1.3 Types of Nephrons
2.1.4 Juxtaglomerular Apparatus
2.1.5 Vascular Supply and Innervation of Kidney
2.1.5.1 Vascular Supply
2.1.5.2 Innervation of Kidney
2.1.6 Functions of Kidney
2.1.7 Recent Advances
2.2 Glomerular Filtration Rate (GFR)
2.2.1 Mechanism of Generation of GFR
2.2.1.1 Pressure Gradients
2.2.1.2 Filtration Coefficient
2.2.2 Factors Effecting Glomerular Filtration Rate: (Bhaskar and Oommen 2018) 2.2.3 Regulation of Glomerular Filtration Rate
2.2.4 Effect of Vasoconstrictors and Vasodilators (Hall and Brands 2012)
2.2.5 Measurement of GFR (Gaspari et al. 1997)
2.2.5.1 Filtration Markers
2.2.5.2 Renal Clearance
2.2.5.3 Creatinine Clearance Test
Estimated Creatinine Clearance
2.2.5.4 SNGFR Estimation Technique (Moore 1984)
2.3 Transport of Solute Across Kidneys
2.3.1 Active Transport
2.3.2 Passive Transport
2.3.3 Proximal Tubule (Curthoys and Moe 2014)
2.3.3.1 Sodium Reabsorption
2.3.3.2 Water Reabsorption 2.3.3.3 Glucose Reabsorption (Mather and Pollock 2011)
2.3.4 Loop of Henle
2.3.5 Distal Convoluted Tubule
2.3.6 Collecting Duct
2.3.6.1 Reabsorption of Solutes
2.3.6.2 Reabsorption of Water
2.4 Urine Concentration and Dilution
2.4.1 Why Is There a Need for Urine Concentration?
2.4.1.1 How Is Urine Concentration Achieved?
The Solute and Water Permeability Characteristics of Each Tubule Segment (Table 2.4)
The Osmotic Gradient Between the Tubule Lumen and Its Surrounding Interstitium (Knepper and Stephenson 1986)

Summary: The central nervous system, which includes the brain and spinal cord, has a high metabolic demand. The physiology of the brain is such that it is easily affected by alterations in other systems, which in turn can compromise cerebral blood flow and oxygenation. Together the brain and spinal cord control the automatic function of our body systems. While other systems of body controls individual functions, central nervous system at the same time does many different functions, especially, controlling the function of other systems. This interaction between the brain and other systems is important when it comes to understanding how injuries to the brain can, at times, produce complications in remote organs or systems of the body, such as the lungs. This book explains the lesser-known crosstalks between acutely or chronically affected brain and lung, describing the pathophysiology of the lung following brain injury and discussing in detail the conflicts between the brain and lungs in relation to the tidal volumes, positive end-expiratory pressures, arterial carbon dioxide and oxygen levels, recruitment maneuvers and positioning, as well as potential therapeutic targets. .

Contents:
Intro
Preface
Acknowledgement
Contents
About the Editors
1: Neurophysiology of Respiratory System
1.1 Introduction
1.2 Historical Perspective
1.3 Phases of Respiration
1.4 Basic Architecture of Neural Network for Control of Respiration
1.5 Neural Substrate for Control of Respiration
1.5.1 Pre-Bötzinger Complex (Pre-BotC)
1.5.2 Post-Inspiratory Complex (PICO)
1.5.3 Parafacial Respiratory Group (pFRG)
1.5.3.1 Lateral Parafacial Respiratory Group (Lateral pFRG)
1.5.3.2 Retrotrapezoid Nucleus (RTN)/Ventral Parafacial Respiratory Group 1.5.3.3 Botzinger Complex (BotC)
1.5.3.4 Kölliker-Fuse (KF)
1.6 Afferents
1.6.1 Peripheral Chemoreceptor
1.6.1.1 Carotid Body
1.6.1.2 Aortic Bodies
1.6.2 Central Chemoreceptor
1.6.2.1 Mechanism of CO2/H+ Sensing
1.6.3 Mechanoreceptors and Chemosensitive Receptors in Lungs
1.6.3.1 Mechanoreceptors
1.6.3.2 Chemosensitive Receptors
1.6.4 Metabotropic Receptors in Muscles
1.6.5 Central Pathways and NTS
1.7 Neural Network for the Respiratory Rhythm
1.7.1 Neural Substrate for Inspiratory Rhythm
1.7.1.1 Pacemaker Model 1.7.1.2 Burstlet Model (Modification of Group Pacemaker Model)
1.7.1.3 Network Ring Model
1.7.2 Neural Substrate for Post-Inspiratory Phase
1.7.3 Neural Network for Active Expiration
1.7.4 Neural Network for Sighs
1.8 Neural Network for Respiratory Pattern
1.8.1 Phase Switching
1.8.2 Proposed Operation of the Model
References
2: Physiological Modulation of Respiration and Respiratory Reflexes
2.1 Introduction
2.2 Ventilatory Response to Changes in PaO2 and PaCO2 and Exercise
2.2.1 Hypoxic Ventilatory Response 2.2.1.1 Effect of Intensity of Hypoxia on HVR
2.2.1.2 Effect of Duration of Hypoxia on HVR
2.2.1.3 Effect of Intermittent Hypoxia on HVR, Long-Term Facilitation
2.2.2 Hypercapnic Ventilatory Response and Effect of pH
2.2.3 Mechanism of Hypoxic Ventilatory Response and Hypercapneic Ventilatory Response
2.2.4 Arousal in Hypoxia and Hypercapnia
2.2.5 Exercise Hyperpnea
2.2.5.1 Ventilatory Changes During Exercise
2.2.5.2 Mechanism of Exercise Hyperpnea
2.2.5.3 Plasticity of the Exercise Hyperpnea
2.3 Respiratory Reflexes 2.3.1 Reflexes for Protection and Clearing of Airways
2.3.1.1 Nasotrigeminal Reflex
2.3.1.2 Sneeze Reflex
2.3.1.3 Aspiration Reflex
2.3.1.4 Expiration Reflex
2.3.1.5 Tracheo-bronchial Cough Reflex
2.3.2 Reflexes for Modulation of Respiration
2.3.2.1 Reflexes Originating from Mechanoreceptors
2.3.2.2 Reflexes from C-type Unmyelinated Fibres
2.3.2.3 Upper Airway Negative Pressure Reflex
2.3.2.4 Sigh and Gasps
2.3.3 Modulation of Breathing in Behavioural States and Non-respiratory Motor Activities

Contents:
CHAPTER 1
I CONSCIOUSNESS
The Problem of Consciousness
Neurobiology of Consciousness Models of Consciousness
The Global Workspace Model
The Dynamic Core Model
Epilogue
Conscious Perception
The Embodied Mind
Understanding the Human Brain by Studying Large Scale Networks
Challenges
II CLINICAL VIEW OF CONSCIOUSNESS
Introduction
The Pathophysiology of Reduced Consciousness
The Construction of the Conscious Brain
The Hierarchy of Consciousness
When Consciousness Fades
Anesthesia
Minimally Conscious State
Altered Consciousness in Neurological Disorders
Disconnection and Neglect
Epilepsy
Narcolepsy
Alzheimer's disease
CHAPTER 2
I MEMORY
Introduction
Different Types of Memory
The Dynamics of Memory Traces
The Molecular Biology of Memory
Neurogenesis: Links to Memory and Behavior
II CLINICAL VIEW OF MEMORY
The Memory Machinery
Infantile Amnesia
Mind, Time and Memory
Mind and Time in Childhood and Adolescence
Re-transcription of Memory
Emotions and Memory
Amnesias and Memory Disorders
Transient Global Amnesia
Chronic or Progressive Amnestic Disorders
CHAPTER 3
I EMOTIONS
Evolving Concept of the Limbic System
Emotion and Behavior
Emotional Systems
The Role of the Frontal Lobe
Social Emotion and Social Norm
II THE DEVELOPMENT OF SELF
Brain Development and the Self
Psychological and Self
Development
True and False Self
Early Parent
Child Relationship
Parenthood
Early Relationship Disorders
CHAPTER 4
I LANGUAGE
The Evolutionary Origin of Language
The Classical Language Regions
The Language Network
The Neural Basis of Speech Perception and Language
Language Learning Disorders
II COMMUNICATION
Introduction
Gestural Communication
Social Interactions or Proto-Conversations
Speech and Language
III MUSIC
Introduction
Music and the Brain
Music in Early Human Development
The Emotional Power of Music
CHAPTER 5
STRESS AND TRAUMA
Stress and the Brain
Neurobiological Responses to Stress
Stress and Mental Disorders
New Avenues for Treatment
Psychic Trauma
Concepts
Psychic Trauma in Children
Psychobiological Aspects
Psychodynamic Aspects
Symptoms and Phases of Psychic Trauma
Familial Aspects
Post-Traumatic Consequences
Post-Traumatic Stress Disorders
Risk for Psychic Traumatization
Children of Mentally or Somatically Ill Parents
Psychotherapeutic Interventions
Adoption
CHAPTER 6
I PAIN AND MIND-BODY
Introduction
Pain Mechanisms and Functions
The Affective Pain System
Notes on Chronic Pain
II SOMATIZATION
PSYCHOSOMATICS
The Mind
Body Dilemma
Psychosomatics
Speaking Body, Speechless Mind
Somatization in Children and Adolescents
CHAPTER 7
RESILIENCE
A Dynamic Concept
Gene
Environment
Interactions
Adoption
Development
Temperament
Stress
Depression
Attachment
Resilience promotion
CHAPTER 8
GRIEF
Introduction
Prolonged Grief Disorder or Complicated Grief
Grief in Children and Adolescents
Pathological Grief and Secret
Transgenerational Transmission of Traumatic Events
Neurobiology of Grief and Depression
New Treatments for Depression
CHAPTER 9
DREAMS AND THE DREAMING BRAIN
History
The 24-Hour Brain
Neurophysiology of Dreams
Transition States of Sleep
Functions of Dreams
Lucid Dreaming
Daydreaming
Nightmares
Music in Dreams
Dream Work in Psychotherapy
CHAPTER 10
NOTES TO PSYCHOTHERAPY
Introduction
Dialogue between Psychoanalysis and Neuroscience
Transference and Intersubjective Relationship
Interpretation / Intervention
Psychoanalytical Therapy for Patients with Adverse Childhood Experiences
Psychotherapy in Children and Adolescents
Indication for Psychoanalytical Therapy
Psychoanalytical Psychotherapy
Play
Psychoanalytical Therapeutic Group Psychodrama
Psychopharmacological Treatment
Narratives
Introduction
Narratives in Psychotherapy.

Summary: This unique and richly illustrated volume presents the state of the art in the comprehensive management of major neurosurgical diseases in the elderly (aged 65 and over). It explores all of the common neurosurgical pathologies affecting elderly patients, and emphasizes the paramount importance of tailored management strategies for quality of life. It highlights updated techniques for anaesthesia and critical care, as well as minimally invasive neurosurgical methods intended for this specific group of patients. Radiosurgery treatment is also discussed, in particular for brain tumours. In western societies, the proportion of elderly citizens has nearly reached 20%, and shows no signs of slowing down. The management of neurosurgical conditions in this particular population requires specific multidisciplinary strategies. To address this situation, a team of internationally respected contributors accurately describe degenerative and traumatic spinal diseases, which account for the majority of admissions among the elderly, as well as brain tumours and intracranial haemorrhages, aspects that are raising new ethical issues. The book mainly addresses the needs of neurosurgeons and geriatric neurologists, but also neuro-oncologists and neuro-anaesthesists working with elderly patients, as well as students in these disciplines.

Contents:
Part 1. Generalities. 1. Rapid growth in the elderly population of the world / Louis G. Pol
2. A brief physiology of the aging / Moncef Berhouma
3. Neurological assessment and neurocognitive evaluation of the elderly / Pierre Krolak-Salmon
Part 2. Neuroanesthesia and critical care. 4. Neurosurgical anesthesia for the elderly: Is age really just a number? / David A. Wyler, Elizabeth M. Gabrielli, W. Andrew Kofke
5. Perioperative neurotoxicity in the elderly; / Elizabeth M. Gabrielli, Roderic G. Eckenhoff
6. Central nervous system infections in the elderly / Rodrigo Hasbun, Allan R. Tunkel
Part 3. Intracranial tumors. 7. Intracranial meningiomas in the elderly / David B. Schul, Chochlidakis Nikos, Chirstianto B. Lumento
8. Brain gliomas in the elderly / Cristina Izquierdo Gracia, Francois Ducray
9. Pituitary adenomas / Paolo Cappabianca, Chiara Caggiano, Domenico Solari, Karol Migliorati, Waleed A. Azab, Elia Guadagno, Marialaura del Basso de Caro, Emmanuel Jouanneau, Luigi M. Cavallo
10. Vestibular schwannoma surgery in the elderly / Philip Y. Sun, Marina L. Castner, Kathryn M. van Abel, Colin L.W. Driscoll, Michael J. Link
11. Management of primary CNS lymphoma in elderly patients / Andreas F. Hottinger, Bianca Moura, Francesco Grandoni, Rita de Micheli
12. Management of brain metastases: Distinctive features in the elderly / Moncef Berhouma
Part 4. Spinal diseases. 13. Degenerative spine disease / Christian Ewald, Albrecht Waschke
14. Spinal injuries of the elderly / Christopher D. Witiw, Laureen D. Hachem, Michael G. Fehlings
15. Extradural vertebral tumors in the elderly / Ryan J. Filler, Timothy T. Roberts, Edward C. Benzel
16. Intramedullary spinal cord tumors / Rajiv R. Iyer, George I. Jallo
17. Intradural extramedullary spoinal tumors / Owoicho Adogwa, Richard G. Fessler
18. Spinal infections / Hideki Nagashima
Part 5. Head injury. 19. Traumatic brain injury in the elderly / Verena Röckelein, Michael Buchfelder, Andrea Kleindienst
20. Chronic subdural haematoma in the elderly / Ellie Edlmann, Peter J. Hutchinson, Angelos G. Kolias
Part 6. Neurovascular. 21. Subarachnoid hemorrhage in the elderly / Mats Ryttlefors, Per Enblad
22. Spontaneous intracerebral hemorrhage in the elderly / Moncef Berhouma, Timothée Jacquesson, Emmanuel Jouanneau
23. Swollen middle cerebral artery stroke in the elderly / Desmond A. Briown, Eelco F.M. Wijdicks
Part 7. Miscellaneous. 24. Trigeminal neuralgia in the elderly / Jonathan Cohen, Hossein Mousavi, Raymond F. Sekula Jr.
25. Hydrocephalus in the elderly: Diagnosis of idiopathic normal / Albert M. Isaacs, Mark G. Hamilton, Michael A. Williams
26. Hydrocephalus in the elderly: Surgical management of idiopathic normal pressure hydrocephalus / Albert M. Isaacs, Michael A. Williams, Mark G. Hamilton
27. Ethics in neurosurgery for the elderly / Farshad Nassiri, Mark Bernstein
Appendix
Index.

Contents:
Introduction
Motivation to this study
AVM definition and angioarchitecture
Feeding arteries
Associated aneurysms
Nidus component
Draining veins
Genetics of arteriovenous malformations
Epidemiology of AVM
Physiology of arteriovenous malformations
Arterial side
Steal phenomenon
Normal perfusion pressure breakthrough
Venous side
Occlusive hyperemia
Compartmental model of AVM nidus
AVM presentation
Hemorrhagic presentation
Morbidity and mortality of AVM related intracranial haemorrhage
Epilepsy presentation
Focal neurologic deficit (FND)
Natural course
AVM grading
Surgical AVM grading
Radiosurgical AVM grading
Imaging
Catheter angiography
Magnetic resonance imaging
Computed tomography
Treatment for brain AVMs
Literature series
Surgery
Endovascular embolization
Stereotactic radiosurgery
Combined treatment
ARUBA study comments.

Summary: "Brain Banking, Volume 150, serves as the only book on the market offering comprehensive coverage of the functional realities of brain banking. It focuses on brain donor recruitment strategies, brain bank networks, ethical issues, brain dissection/tissue processing/tissue dissemination, neuropathological diagnosis, brain donor data, and techniques in brain tissue analysis. In accordance with massive initiatives, such as BRAIN and the EU Human Brain Project, abnormalities and potential therapeutic targets of neurological and psychiatric disorders need to be validated in human brain tissue, thus requiring substantial numbers of well characterized human brains of high tissue quality with neurological and psychiatric diseases"--Publisher's description.

Contents:
Section I. Brain donor recruitment strategies. The Netherlands Brain Bank for Psychiatry
Brain donation procedures in the sudden death brain bank in Edinburgh
Section II. Brain bank networks. Autism BrainNet
The NIH NeuroBioBank: Creating opportunities for human brain research
Section III. Ethical Aspects of Brain Banking and Management of Brain Banks
Design of a European code of conduct for brain banking
A review of brain biorepository management and operations
A new viewpoint: running a non-profit brain bank as a business
Section IV. Brain dissection, tissue processing and tissue dissemination. The New York Brain Bank of Columbia University: Practical highlights of 35 years of experience
Neurochemical markers as potential indicators of post-mortem tissue quality
Section V. Neuropathological diagnosis. Minimal neuropathological diagnosis for brain banking in the normal middle aged and aged brain and in neurodegenerative disorders
Brain donation at autopsy: Clinical characterization and toxicological analyses
Section VI. Brain donor data: clinical, genetic, radiologic and research data storage and mining. Information technology for brain banking
Collecting, storing and mining research data in a brain bank
What can we learn about brain donors? Use of clinical information in human postmortem brain research
The art of matching brain tissue from patients and controls for postmortem research
Section VII. Human brain tissue analyses: old and new techniques. Considerations for optimal use of postmortem human brains for molecular psychiatry: Lessons from schizophrenia
Epigenetic analysis of human brain tissue
Laser microdissection and gene expression profiling in the human postmortem brain
Purification of cells from fresh human brain tissue: Primary human glial cells
Proteomics and lipidomics in the human brain
3-D imaging in the post-mortem human brain with CLARITY and CUBIC
Neuronal life after death: Electrophysiological recordings from neurons in adult human brain tissue obtained through surgical resection or post-mortem
Post-mortem magnetic resonance imaging
Cyto- and receptorarchitectonic mapping of the human brain
Mapping pathological circuitry in schizophrenia

Contents:
Brain computation
Brain overview
Neurons and circuits
Cortical memory
Programs via reinforcement
Sensory-motor routines
Motor routines
Operating system
Decision making
Emotions
Consciousness.

Summary: This book is about the field of brain-computer interfaces (BCI) and the unique and special environment of active implants that electrically interface with the brain, spinal cord, peripheral nerves, and organs. At the heart of the book is the matter of repairing and rehabilitating patients suffering from severe neurologic impairments, from paralysis to movement disorders and epilepsy, that often requires an invasive solution based on an implanted device. Past achievements, current work, and future perspectives of BCI and other interactions between medical devices and the human nervous system are described in detail from a pragmatic point of view. Reviews the Active Implantable Medical Devices (AIMDs) industry and how it is moving from cardiac to neuro applications Clear, easy to read, presentation of the field of neuro-technologies for human benefit Provides easy to understand explanations about the technical limitations, the physics of implants in the human body, and realistic long terms perspectives.

Contents:
Intro; Preface; Contents; About the Author; Abbreviations and Acronyms;
Chapter 1: Introduction; 1.1 Brain-Computer Interface (BCI); 1.2 Technology Versus Science; 1.3 This Is Not Science Fiction; 1.3.1 Cochlear Implants (CI); 1.3.2 Deep Brain Stimulation (DBS); 1.3.3 Spinal Cord Stimulation (SCS); 1.3.4 Sacral Nerve Stimulation (SNS); 1.3.5 Vagal Nerve Stimulation (VNS); 1.3.6 Various Devices; 1.4 Pioneers, Doers, and Dreamers; 1.4.1 Pioneers; 1.4.1.1 Pacemakers; 1.4.1.2 Implantable Cardiac Defibrillators (ICDs); 1.4.1.3 Cochlear Implants; 1.4.1.4 Deep Brain Stimulation 1.4.1.5 Spinal Cord Stimulation1.4.2 Doers; 1.4.2.1 Spinal Cord Stimulation; 1.4.2.2 Sacral Nerve Stimulation; 1.4.2.3 Vagal Nerve Stimulation; 1.4.2.4 Retinal Implants; 1.4.2.5 Peripheral Nerve Stimulation (PNS); 1.4.2.6 Intelligent Prosthesis for Amputees; 1.4.2.7 Diagnostic and Monitoring of Epileptic Patients; 1.4.2.8 BCI for Sensing Motor Areas of the Cortex; 1.4.2.9 Others; 1.4.3 Dreamers; 1.5 The Age of Neuro-Technologies; 1.5.1 Convergence of Technologies; 1.5.2 Limitations of the Pharma- and Bio-Industries; 1.5.3 Unmet Medical Needs; References;
Chapter 2: From Concept to Patient 2.1 Translational Medicine2.1.1 From Ideas to Products; 2.1.2 Valley of Death; 2.1.3 Multicultural Approach; 2.1.4 Setting Priorities; 2.1.5 Prepare a Plan; 2.1.6 Think About Costs; 2.2 Understanding Our Environment; 2.2.1 Regulated Environment; 2.2.2 Users' Needs; 2.2.3 Human Factors; 2.2.4 Implantology; 2.2.5 Think About Patients and Healthcare Players; 2.2.6 Do Not Listen to Engineers; 2.2.7 Check What Others Are Doing; 2.2.8 Search Reasons of Successes and Failures; 2.2.9 Cumulated Cash-Flow; 2.2.10 Reimbursement; 2.2.11 Global Social Costs; 2.2.12 Intellectual Property (IP); References 3.4.5 Retinal Implants (RI)3.4.6 Urinary Incontinence (UI); 3.4.7 NeuroPace; 3.4.8 Various; 3.5 Long-Term Clinical Perspectives; References;
Chapter 4: The Human Body: A Special Environment; 4.1 Active Implantable Medical Devices (AIMDs); 4.2 A Special Environment; 4.2.1 Not Negotiable; 4.2.2 Laws of Physics; 4.2.3 Surgical Aspects; 4.2.4 Reaction of Body Tissues; 4.3 Biocompatibility; 4.4 Biostability; 4.5 Corrosion; 4.5.1 Generalities on Corrosion of AIMDs; 4.5.2 Specificities of Corrosion in the Human Body; 4.6 Cleanliness; 4.7 Sterility; 4.8 Accelerated Aging
Chapter 3: Targets of Neuro-Technologies3.1 Interfacing with the Nervous System; 3.2 Invasiveness; 3.2.1 Noninvasive; 3.2.2 Not So Invasive; 3.2.3 Invasive; 3.3 Invasive Interfaces; 3.3.1 Interfacing with the Brain; 3.3.2 Interfacing with the Spinal Cord; 3.3.3 Interfacing with the Vagal Nerve; 3.3.4 Interfacing with Peripheral Nerves; 3.3.5 Interfacing with Organs; 3.4 Achievements; 3.4.1 Cochlear Implants (CI); 3.4.2 Deep Brain Stimulation (DBS), Parkinson's Disease (PD); 3.4.3 Spinal Cord Stimulation (SCS) for Chronic Back Pain (CBP); 3.4.4 Vagal Nerve Stimulation (VNS)

Contents:
1. Human brain function and brain-computer interfaces
2. Brain-computer interfaces: definitions and principles
3. Stroke and potential benefits of brain to computer interface
4. Brain-computer interfaces for people with amyotrophic lateral sclerosis
5. Brain damage by trauma
6. Spinal cord lesions
7. Brain:computer interfaces for communication
8. Applications of brain-computer interfaces to the control of robotic and prosthetic arms
9. BCI for rehab ('not control')
10. Video games as rich environments to foster brain plasticity
11. Consciousness and communication brain-computer interfaces in severely brain-injured patients
12. Smart neuromodulation in movement disorders
13. Bidirectional brain computer interfaces
14. Brain-computer interfaces and virtual reality for neurorehabilitation
15. Monitoring performance of professional and occupational operators
16. Self-Health Monitoring and wearable neurotechnologies
17. Brain-computer interfaces for basic neuroscience
18. Electroencephalography
19. iEEG: dura-lining electrodes
20. Local field potentials for BCI control
21. Real-time fMRI for brain-computer interfacing
22. Merging brain-computer interface and functional electrical stimulation technologies for movement restoration
23. General principles of machine learning for brain-computer interfacing
24. Ethics and the emergence of brain-computer interface medicine
25. Industrial perspectives on brain-computer interface technology
26. Hearing the needs of clinical users.

Contents:
Part I: User training. Advances in user-training for mental-imagery-based BCI control: Psychological and cognitive factors and their neural correlates / C. Jeunet, B. N?Kaoua, F. Lotte
Part II: Non-invasive decoding of 3D hand and arm movements. From classic motor imagery to complex movement intention decoding: The noninvasive Graz-BCI approach / G.R. Müller-Putz, A. Schwarz, J. Pereira, P. Ofner
3D hand motion trajectory prediction from EEG mu and beta bandpower / A. Korik, R. Sosnik, N. Siddique, D. Coyle
Multisession, noninvasive closed-loop neuroprosthetic control of grasping by upper limb amputees / H.A. Agashe, A.Y. Paek, J.L. Contreras-Vidal
Part III: Patients studies and clinical applications. Brain?computer interfaces in the completely locked-in state and chronic stroke / U. Chaudhary, N. Birbaumer, A. Ramos-Murguialday
Brain?machine interfaces for rehabilitation of poststroke hemiplegia / J. Ushiba, S.R. Soekadar
Neural and cortical analysis of swallowing and detection of motor imagery of swallow for dysphagia rehabilitation?A review / H. Yang, K.K. Ang, C. Wang, K.S. Phua, C. Guan
A cognitive brain?computer interface for patients with amyotrophic lateral sclerosis / M.R. Hohmann, T. Fomina, V. Jayaram, N. Widmann, C. Förster, J. Just, M. Synofzik, B. Schölkopf, L. Schöls, M. Grosse-Wentrup
Brain?computer interfaces for patients with disorders of consciousness / R.M. Gibson, A.M. Owen, D. Cruse
Part IV: Non-medical applications. A passive brain?computer interface application for the mental workload assessment on professional air traffic controllers during realistic air traffic control tasks / P. Aricò, G. Borghini, G. Di Flumeri, A. Colosimo, S. Pozzi, F. Babiloni
3D graphics, virtual reality, and motion-onset visual evoked potentials in neurogaming / R. Beveridge, S. Wilson, D. Coyle
Part V: BCI in practice and usability considerations. Interfacing brain with computer to improve communication and rehabilitation after brain damage / A. Riccio, F. Pichiorri, F. Schettini, J. Toppi, M. Risetti, R. Formisano, M. Molinari, L. Astolfi, F. Cincotti, D. Mattia
BCI in practice / D.J. McFarland, T.M. Vaughan.

Contents:
Anatomy of the nervous system
Functional neuroimaging
Cerebral electrogenesis
Physiological markers for controlling active and reactive BCIs
Neurophysiological markers for passive brain-computer interfaces
Electroencephalography data preprocessing
EEG feature extraction
Analysis of extracellular recordings
Statistical learning for BCIs
Adaptive methods in machine learning
Human learning for brain-computer interfaces
Brain-computer interfaces for human-computer interaction
Brain training with neurofeedback.

Summary: This volume summarizes the ethical, social and cultural contexts of interfacing brains and computers. It is intended for the interdisciplinary community of BCI stakeholders. Insofar, engineers, neuroscientists, psychologists, physicians, care-givers and also users and their relatives are concerned. For about the last twenty years brain-computer-interfaces (BCIs) have been investigated with increasing intensity and have in principle shown their potential to be useful tools in diagnostics, rehabilitation and assistive technology. The central promise of BCI technology is enabling severely impaired people in mobility, grasping, communication, and entertainment. Successful applications are for instance communication devices enabling locked-in patients in staying in contact with their environment, or prostheses enabling paralysed people in reaching and grasping. In addition to this, it serves as an introduction to the whole field of BCI for any interested reader. -- Provided by publisher.

Summary: This book is intended for frontline doctors the world over to take away the myth surrounding the emergency CT brain scan and to empower them to serve their patients better. It presents and elucidates the basic, almost foolproof steps in their interpretation.

Contents:
Introduction to the basics of brain CT scan
Head injury
Brain haemorrhage and infarction : stroke
Hydrocephalus
Tumours and infections (SOL)
Advanced uses of brain CT scan.

Contents:
History of brain death
Neurology of brain death
International criteria of brain death
Beliefs about brain death
Critics and brain death
Procurement after brain death
Clinical problems in brain death and organ donation.

Contents:
Immunostaining of the Developing Embryonic and Larval Drosophila Brain
Non-Fluorescent RNA In Situ-Hybridization Combined with Antibody Staining to Visualize Multiple Gene Expression Patterns in the Embryonic Brain of Drosophila
Analysis of Complete Neuroblast Cell Lineages in the Drosophila Embryonic Brain via DiI-Labeling
Flybow to Dissect Circuit Assembly in the Drosophila Brain
Immunofluorescent Labeling of Neural Stem Cells in the Drosophila Optic Lobe
Using MARCM to Study Drosophila Brain Development
Dye Coupling and Immunostaining of Astrocyte-Like Glia Following Intracellular Injection of Fluorochromes in Brain Slices of the Grasshopper, Schistocerca gregaria
Methods in Brain Development of Molluscs
In Situ Hybridization and Immunostaining of Xenopus Brain
Microinjection Manipulations in the Elucidation of Xenopus Brain Development
Morpholino Studies in Xenopus Brain Development
Sensitive Whole-Mount Fluorescent In Situ Hybridization in Zebrafish Using Enhanced Tyramide Signal Amplification
Dynamic Neuroanatomy at Subcellular Resolution in the Zebrafish
Anatomical Dissection of Zebrafish Brain Development
Immunohistochemistry and In Situ Hybridization in the Developing Chicken Brain
Transplantation of Neural Tissue: Quail-Chick Chimeras
RNAi-Based Gene Silencing in Chicken Brain Development
Immunohistochemistry and RNA In Situ Hybridization in Mouse Brain Development
In Utero Electroporation to Study Mouse Brain Development
The Cre/Lox System to Assess the Development of the Mouse Brain.

Contents:
Physiology of cerebral blood vessels / Ute Lindauer
Blood-brain interfaces organization in relation to inorganic ion transport, CDF secretion, and circulation / Jean-Franc̦ois Chersi-Egea and Helle Damkier
Noninvasive imaging techniques for brain edema / Andre Obenaus and Jérôme Badaut
Experiemental techniques to investigate the formation of brain edema in vivo / Nikolaus Plesnila
In vitro models of the blood-brain barrier to better understand the pathophysiology of brain edema / Abraham J. Al-Ahmad
The extracellular and perivascular spaces of the brain / Mchelle E. Pizzo and Robert G. Thorne
Blood-brain barrier mechanisms of edema formation / Martha E. O'Donnell, Heike Wulff and Yi-Je Chen
Mechanisms of cell-volume regulation in the central nervous system / Nikolaus Plesnila and Oliver Kempski
Role of aquaporins in the formation and resolution of brain edema / Beatriz Rodriguez-Grande, Jan-Pieter Konsman and Jérôme Badaut
Sur1-Tirpm4-promising target for brain edema treatment in brain edema / Sebastian Urday, Kevin N. Sheth and J. Marc Simard
Role of matrix metalloproteinsases in brain edema / Changjun Yang an Eduardo Candelario-Jalil
Edema and BBB beakdown in stroke / Kathleen E. Salmeron, Danielle N. Edwards, Justin F. Fraser and Gregory J. Bix
Brain edema formation in traumatic brain injury / Sighild Lemarchant and Jérôme Badaut
Spinal cord edema after spinal cord injury / Newton Cho, Laureen D. Hachem and Michael G. Fehlings
Brain edema in acute liver failure / Roger F. Butterworth
Blood-brain barrier and edema in brain tumors / Andreas F. Mack, Hartwig Wolburg and Petra Fallier-Becker
Water homeostasis dysfunction in epilepsy / Devin K. Binder
Water homeostasis dysfunctions and edema in neuroinflammatory disease / Klaus G. Petry and Andreas Bikfalvi
Experimental therapies for brain edema and intracranial hypertension / Katrin Rauen and Nikolaus Plesnila
Clinical monitoring of brain edema / Sandro M. Krieg and Sebastian Ille
Brain edema in developing brain diseases / Raffaella Moretti, Vibol Chhor, Luigi Titomanlio, Bobbi Fleiss
Cerebral edema in cerebrovascular diseases / Stephane Olindo and Igor Sibon
Traumatic brain injury and edema treatment / Klaus Zweckberger
Treatment of edema formation in oncology / Oliver Schnell and Jörg-Christian Tonn
Perspectives on future translational research on brain edema / J. Marc Simard, Jérôme Badaut and Nikolaus Plesnila.

Contents:
Brain Edema and Anesthesia
Clinical Management of brain edema
Neural ICU and edema management updates
Preconditioning symposium for edema and cellular injury
Microglia in edema and cell death
Opioid receptor and brain injury
Energy metabolism after brain injury
Metal ion in brain edema and tissue injury
Vascular biology of brain edema
Brain edema in pediatric neurological disorders
Hemorrhage or stroke edema section
CNS trauma section
Neuroimaging of brain edema: advances and biomarkers
Neurobehavioral testing for brain edema assessment
Brain edema and cellular treatment
HBO, NBO and other medical gas for edema and tissue protection
New treatments and/or technologies for edema and cell death.

Contents:
Determination of CO2 Production in Subcellular Preparations like Synaptosomes and Isolated Mitochondria Using 14C-Labeled Substrates and Radioactive CO2 Measurements
Transport of Lactate: Characterization of the Transporters Involved in Transport at the Plasma Membrane by Heterologous Protein Expression in Xenopus Oocytes
Primary Cultures of Astrocytes and Neurons as Model Systems to Study the Metabolism and Metabolite Export from Brain Cells
Metabolic Mapping of Astrocytes and Neurons in Culture Using Stable Isotopes and Gas Chromatography-Mass Spectrometry (GC-MS)
Metabolic Flux Analysis Tools to Investigate Brain Metabolism In Vitro
Fluorescent Nanosensor Based Flux Analysis: Overview and the Example of Glucose
Mitochondrial Bioenergetics Assessed by Functional Fluorescence Dyes
RNA Interference as a Tool to Selectively Down-Modulate Protein Function
Localizing and Quantifying Metabolites In Situ with Luminometry: Induced Metabolic Bioluminescence Imaging (imBI)
A Chip Off the Old Block: The Brain Slice as a Model for Metabolic Studies of Brain Compartmentation and Neuropharmacology
Integrated Measurements of Electrical Activity, Oxygen Tension, Blood Flow, and Ca2+-Signaling in Rodents In Vivo
Measuring Cerebral Hemodynamics and Energy Metabolism by Near-Infrared Spectroscopy
Compartmental Analysis of Metabolism by 13C Magnetic Resonance Spectroscopy
Positron Emission Tomography of Brain Glucose Metabolism with [18F]Fluorodeoxyglucose in Humans.

Summary: "In Sapiens, Yuval Noah Harari argues that humankind's greatest invention is our ability to create and believe fictions. While all other animals communicate realities with which they interact, humans create a separate layer of subjective, interpretative realities. The fiction most universally embraced today is money. "Dollar bills have absolutely no value except in our collective imagination, but everybody believes in the dollar bill," says Harari. Harari goes on to state that humans have been living in a dual reality. "On the one hand, the objective reality of rivers, trees, and lions; and on the other hand, the imagined reality of gods, nations, and corporations." In medicine, humans have also created two realities. Clinicians describe what they see, an objective reality, but the medical community then tries to explain and give meaning to what they see, creating a second,"-- Provided by publisher.

Summary: This book aims to provide a state-of-the-art summary of what is currently known about brain glycogen metabolism, detailing the recent advances in our understanding of why glycogen is so critical for normal brain function. The role of glycogen in cellular neurophysiology remains largely unclear and its specific contribution to the energy demand of brain cells is still elusive. Glycogen is the sole cerebral glucose reserve and is emerging as a fundamental component of brain energy metabolism. Pharmacological or genetic manipulation of glycogen metabolism in the brain impairs memory formation and increases susceptibility to epileptic seizures and cortical spreading depression. Glycogen is also directly implicated in abnormal neuronal excitability and mental retardation that characterize brain disorders like Lafora disease and Pompe disease.

Contents:
1. Introduction or Preface
2. Structure and regulation of glycogen synthase in the brain
3. Structure and regulation of glycogen phosphorylase in the brain
4. Regional distribution of glycogen in the brain
5. Metabolism of glycogen in the brain white matter
6. Metabolism of glycogen in the brain gray matter
7. Contribution of glycogen to brain energy metabolism
8. Brain glycogen, compartmentation and ion/transmitter homeostasis
9. Role of brain glycogen in learning and memory
10. Brain glycogen content and turnover during sleep-wake cycle
11. Brain glycogen metabolism in response to exercise
12. Brain glycogen metabolism in neuronal excitability and epilepsy
13. Brain glycogen metabolism in hypoglycemia and diabetes.

Summary: This is a single-authored book written by a world-class neuroradiologist with extensive experience in traumatic brain injury (TBI). It features six graphic-intense chapters depicting and expounding upon the complexity of TBI. Culled from nearly three decades of studying civilian TBI and five years of intensive study of TBI sustained from combat, terrorism, and natural disasters, this work is an exhaustive and innovative authority on the current approaches and applications of civilian and combat TBI. The text is sectored into six chapters based on pathophysiology, each augmented with numerous images and illustrations. The book gives special attention to neuroimaging, but is reinforced with relevant clinical correlation. This monograph is unique because it is first in class as an omnibus for the radiologist, neurologist, neurosurgeon, maxillofacial surgeon, emergency physician, pediatrician, ophthalmologist, and the rehabilitation team.

Contents:
In comparison to prior wars, more troops are surviving
Blast injury basics
The weapons of war and terrorism
How does combat TBI differ from civilian TBI? 12 lessons
Transferring lessons to the home front.

Summary: "The only review book currently available in this complex field, Brain Injury Medicine: Board Review focuses on the prevention, diagnosis, treatment, and management of individuals with varying severity levels of brain injury. Focused, high-yield content prepares you for success on exams and in practice, with up-to-date coverage of traumatic brain injury (TBI), stroke, CNS neoplasms, anoxic brain injury, and other brain disorders. This unique review tool is ideal for residents, fellows, and practitioners studying or working in the field and preparing to take the brain injury medicine exam"--Publisher's description.

Contents:
Section 1: Brain anatomy and physiology. Neuroanatomy correlates
Pathophysiology and basic sciences
Section 2: Traumatic brain injury severity & patterns. Mild TBI (concussion), moderate to severe TBI
TBI by pattern: penetrating, non- penetrating, blast injury
Brain death criteria
Section 3: Epidemiology and risk factors. Epidemiology and public health & prevention
Proteomic, genetic, and epigenetic biomarkers in TBI
Prognosis and recovery patterns
Section 4: Emergency Room and intensive care management. Prehospital care
Acute emergency management (non-surgical care & surgical care)
Critical care management
Complications
Section 5: Evaluation and diagnosis. Physical examination, signs and symptoms
Diagnostic procedures and electrophysiology
Neuroimaging (structural and functional)
Functional evaluation
Intensity of services, specialized rehabilitation therapies, interdisciplinary team management
Section 6: Complications and management. Cardiovascular and pulmonary
GI and nutrition
Genitourinary
Soft tissue and orthopedic condition
Pain
Neuroendocrine/ metabolic/ hormonal
Paroxysmal sympathetic hyperactivity
Spasticity & contractures
Post-traumatic hydrocephalus
Cranial nerve disorders
Seizure disorder
Movement disorder
Pressure injuries, bed rest and deconditioning
Dysphagia and aspiration
Speech and language
Cognitive dysfunction
Neurosensory dysfunction
Emotional dyscontrol
Agitation and restlessness
Sleep dysfunction and fatigue
Mood disorders
PTSD
Suicide, personality d/o, anxiety
Substance abuse
Sexuality and intimacy
Section 7: Rehabilitation concepts. Therapeutic exercise/rehabilitation
Assistive technology
Community re-entry
Involving family in rehabilitation: role of physiatry
Section 8: Special topics. Pediatric TBI
Geriatric TBI
Military TBI
Sports concussion
Gender specific issues in TBI
Post-concussion syndrome assessment, management and Rx
Nontraumatic brain injury
Dual diagnosis: TBI and SCI
Anoxic brain injury
Doc and rehabilitation
Complementary alternative therapies
Neuromodulation & neuroprosthetics
Neuropharmacology
Neurodegeneration and dementia
Basic statistics/research methods
Ethics and law.

Summary: This work offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images.

Contents:
Volume 1. Acquisition methods, methods and modeling
Volume 2. Anatomy and physiology, systems
Volume 3. Social cognitive neuroscience, cognitive neuroscience, clinical brain mapping.

Summary: "Despite advances in imaging techniques to identify eloquent cortical brain regions and subcortical white matter, brain mapping is the only method for obtaining real-time information with high sensitivity and specificity. This groundbreaking technology greatly enhances the neurosurgeon's ability to safely resect challenging lesions located in eloquent areas of the brain. The book starts with discussion of preoperative aspects, including the history of brain mapping and anatomy of eloquent cortical and eloquent white matter tracts. Subsequent chapters cover perioperative aspects of brain mapping including indirect and direct functional mapping, the role of neurophysiology, awake craniotomy operating room set-up and surgical instruments, and anesthetic considerations. Diverse awake and asleep brain mapping techniques are described for various intracranial pathologies, as well as advances in postoperative recovery of neurological function including physical and speech therapy"-- Provided by publisher.

Contents:
The Early History of Intra-Operative Brain Mapping / Courtney Pendleton, Kaisorn L. Chaichana, and Alfredo Quinones-Hinojosa
Anatomy of Eloquent Cortical Brain Regions / Antonio Cesar de Melo Mussi and Evandro Pinto da Luz de Oliveira
Anatomy of Eloquent White Matter Tracts / Vicent Quilis-Quesada and Shao-Ching Chen
Direct Functional Mapping Using Radiographic Methods (fMRI and DTI) / Erik H. Middlebrooks, Vivek Gupta, and Prasanna Vibhute
Indirect Functional Mapping Using Radiographic Methods / Vivek Gupta, Erik H. Middlebrooks, and Prasanna Vibhute
Neurophysiology of Identifying Eloquent Regions / Tasneem F. Hasan and William O. Tatum IV
Extraoperative Mapping for Epilepsy Surgery : Epilepsy Monitoring, Wada, and Electrocorticography / Emily L. Johnson and Eva K. Ritzl
Neuropsychologist's Role in the Management of Brain Tumor Patients / David S. Sabsevitz, Kathleen H. Elverman, Kyle Nol, and Jeffrey Wefel
Awake Craniotomy Operating Room Setup and Surgical Instruments / Karim ReFaey, Shashwat Tripathi, Sanjeet S. Grewal, Kaisorn L. Chaichana, and Alfredo Quinones-Hinojosa
Anesthetic Considerations for Intraoperative Cerebral Brain Mapping / Elird Bojaxhi and Perry Bechtle
Speech Mapping / Shawn Hervey-Jumper and Mitchel Berger
Motor Mapping (Rolandic, Pre-Rolandic, Insular Cortex) / N.U. Farrukh Hameed, Peng Wang, Geng Xu, Jie Zhang, and Jin-song Wu
Awake Subcortical Mapping of the Ventral and Dorsal Streams for Language / Hugues Duffau Surgery Around the Command and Control Axis : The Default Mode, Control, and Frontal Aslant Systems / Michael E. Sughrue
Mapping and Surgery of Insular Tumours / Matthew A. Kirkman and George Samandouras
Mapping of the Visual Pathway / Lina Marenco-Hillembrand and Kaisorn L. Chaichana
Seizure Mapping Surgery / TBD
Asleep Motor Mapping / Deependra Mahato, Alison Ho, and Javed Siddiqi
Brainstem and Spinal Cord Mapping Mohammad / Hassan A. Noureldine, Nir Shimony, Rechdi Ahdab, and George I. Jallo
Importance of Rehabilitation After Eloquent Brain Surgery / Kenneth Ngo, Andrea Davis, Russell Addeo, Jodi Morgan, Jennifer Walworth, and Sarah Chamberlain
Emergence of Deep Learning Methods for DBS-Evoked Functional Connectomics / Christine Edwards, Abbas Kouzani, Kendall Lee, and Erika Ross
Neuroplasticity and Rewiring of the Brain / Juan A. Barcia, Maria Perez-Garoz, and Cristina Nombela
Radiating in Eloquent Regions / Henry Ruiz-Garcia, Jennifer Peterson, and Daniel M. Trifiletti.

Summary: With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. This volume fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types -- lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection.

Contents:
Brain metastases
Epidemiology of central nervous system metastases
Involvement of the CXCL12/CXCR4/CXCR7 axis in brain metastases
Non-uniform distribution of metastatic intracranial tumors in cancer patients
Targeting angiogenesis, enhancing radiosensitization and crossing the blood-brain barrier for brain metastases
Second malignancies in children following treatment for neuroblastoma
The role of chemotherapy in metastatic brain tumors
Multiple metastases to the brain from primary cancers : whole brain radiotherapy
Synovial sarcoma metastasized to the brain
Multiple small brain metastases with limited focal brain edema from non-small cell lung cancer with epidermal growth factor receptor mutations
Brain metastasis of patients with lung adenocarcinoma : epidermal growth factor receptor mutations and response to whole-brain radiation therapy
Metastatic spread of lung cancer to brain and liver : role of CX3CR1
Solitary brain metastasis from non-small cell lung cancer : treatment with linac-based stereotactic radiosurgery
Brain metastases from non-small cell lung cancer : clinical benefits of erlotinib and gefitinib
Bispecific targeted toxin DTATEGF against metastatic NSCLC brain tumors
Intracranial disease in patients with non-small cell lung cancer : treatment with erlotinib
Radiation management of synchronous brain metastases from non-small cell lung cancer
Brain metastasis after prophylactic cranial irradiation in patients with small cell lung cancer
Brain metastasis from small-cell lung cancer with high levels of placental growth factor
Brain metastases from lung cancer
Lambert-Eaton myesthenic syndrome and brain metastasis from occult small cell lung carcinoma : a clinician's perspective.

Summary: Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors fills that gap, serving as the first two-part reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types - lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age- and gender-related trends are also discussed, as is the use of biomarkers for early detection.

Contents:
Brain metastasis from solid tumors
The role of surgical resection for metastatic brain tumors
Whole-brain radiotherapy for brain metastases: is the therapeutic window enlarging?
Brain metastasis in patients with non-small cell lung cancer: response to epidermal growth factor receptor tyrosine kinase inhibitors
Brain metastasis from non-small cell lung cancer: use of epidermal growth factor receptor and HER2 status for targeted therapy
Brain metastases from non-small cell lung cancer: current evidence in management using tyrosine kinase inhibitor and whole-brain radiation therapy
Brain metastasis in patients with non-small cell lung cancer: immunohistochemical markers
Brain metastasis from breast cancer: molecular mechanisms
New targeted therapies for brain metastases from breast and lung cancer and melanoma
Breast cancers with brain metastases
Brain metastases in melanoma patients: treatment with adjuvant postoperative whole-brain radiotherapy
Melanoma progression in the brain: role of pericytes, the basal lamina, and endothelial cells in tumor vascularization
Brain metastases from esophageal cancer in the presence of HER-2 overexpression
Brain metastasis from renal carcinoma: locoregional and systemic treatments
Gastrointestinal cancer and brain metastasis outcomes and management
Brain metastasis of colorectal cancer: microenvironment and molecular mechanism
Brain metastasis from nasopharyngeal carcinoma.

Contents:
1. Introduction
2. The management and biology of metastatic cancers to the brain
3. Melanoma metastases are underrepresented in cerebellum compared with metastases from colorectal cancers
4. Risk reductions of recurrence and mortality in melanoma patients using IFN-α
5. Brain metastases from melanoma
6. Pathobiology of brain metastases: molecular mechanisms
7. Role of CDKN₂A mutations and other relevant genes in melanoma predisposition
8. The role of the receptor for advanced glycation end products in malignant melanoma
9. Hydrogen sulfide pathway and cancer
10. Brain metastasis from esophageal cancer
11. Treatment of metastatic melanoma patients bearing c-kit mutation using imatinib mesylate
12. Optimal selection of targeted therapies for melanoma patients: role of the mitogen-activated protein kinase pathway
13. Patients with brain metastases from melanoma: treatment with surgery and radiotherapy
14. The risks and advantages of whole brain radiation therapy in patients with brain metastases
15. Gastrointestinal stromal tumors with intracranial metastasis: treatment strategy and review of the literature
16. Brain metastases from breast cancer in patients receiving trastuzumab
17. Brain metastases from cutaneous melanoma: biology and its implications for more rational therapeutic approaches
18. Treatment of brain metastases from ovarian and endometrial carcinomas using stereotactic radiosurgery
19. Prognostic factors for survival in melanoma patients with brain metastases
20. Management of melanoma therapy-associated toxicities
21. Brain metastases from breast cancer: focus on risk factors, treatment, and clinical outcome.

Summary: This volume elucidates the pivotal ethical and legal issues arising from the use of brain organoids for research, therapeutic and enhancement purposes. The function of the human brain is still a mystery. Until recently, only post-mortem tissue was available for a structural examination of the brain. Consequently, the examination results could only reflect the state at the end of life. However, in order to better understand the development and function of the human brain, dynamic and functional investigations of different human brain cells are necessary. This is where brain organoids, artificially grown in vitro miniature brains, provide the opportunity for more flexible research scenarios. At the same time, however, the use of brain organoids in research and therapy raises the question of how these new entities are to be treated from an ethical and legal point of view. Against this background, this volume aims at clarifying the normative implications of the use of brain organoids in research and therapy. The ethical reflections on the status of brain organoids, informed consent, human-to-animal chimeras and neuro-enhancement are mirrored by corresponding legal analyses. The ethical and legal assessments are preceded by an introduction to the scientific and medical background of the brain organoid technology. A final chapter will be devoted to the issue of whether international harmonization of normative standards for brain organoid research and therapy is feasible and advisable.

Contents:
Chapter 1) Introductory Remarks
Part I) Scientific Background
Chapter 2) Development of Brain Organoids on the Basis of Genome-Edited iPSC-Derived Brain Cells
Chapter 3) Cell-Based Therapy and Genome Editing in Parkinson's Disease: Quo Vadis
Part II) The Status Debate
Chapter 4) Human Cerebral Organoids: Evolving Entities and Their Moral Status
Chapter 5). Legal perspective: What is, or Should Be, the Legal Status of Brain Organoids?
Part III) The Informed Consent Challenge
Chapter 6) Ethical Perspective: Ethics Considerations Regarding Donors and Patients Consent
Chapter 7) The Legal Perspective: The Legal Requirements forand Limits tothe Donors and the Patients Consent
Part IV) The Chimera Issue
Chapter 8) Moral Permissibility of Transplantation of Human Brain Organoids into Animals
Chapter 9) Transplantation of Human Brain Organoids into Animals - The Legal Issues
Part V) The Enhancement Conundrum
Chapter 10) Building a Better Beast: Enhancing the Minds of Animals
Chapter 11) Legal Arguments in Favour of and Against Neuroenhancement by Means of Brain Organoids
Part VI) The Harmonization Problem
Chapter 12) Legal Perspective: A Global Harmonisation of Legal Standards for Brain Organoid Research and Therapy?. .

Contents:
Intro
Progress in Brain Research
Copyright
Contributors
Contents
Acknowledgments
Preface
References
Chapter 1: Histamine H3 and H4 receptors modulate Parkinson's disease induced brain pathology. Neuroprotective effects of ...
1. Introduction
1.1. Histaminergic system in the brain
1.2. Histaminergic receptors in the brain
1.3. Histamine in brain diseases
1.3.1. Cognitive dysfunction and Alzheimer's disease
1.3.2. Motor disorders and Parkinson's disease
1.3.3. Schizophrenia
1.3.4. Multiple sclerosis
1.3.5. Sleep disorders 1.3.6. Addictive disorders
2. Histaminergic system alterations in Parkinson's disease
2.1. Histamine concentration in PD
2.2. Histaminergic nerve fibers in PD
2.3. Histaminergic gene and receptors in PD
2.3.1. HMT and HDC gene expression are altered in PD brain
2.3.2. Histamine H3 and H4 receptor expression are altered in PD brain
3. Our own investigations on histamine modulation of Parkinson's disease
3.1. Methodological consideration
3.1.1. Animals
3.2. Animal model of PD
3.3. Modulation of histaminergic agents 3.3.1. Histamine H3 receptor inverse agonist BF2649
3.3.2. Histamine H3 receptor antagonist and partial H4 receptor agonist clobenpropit
3.3.3. Anti-histamine mouse monoclonal antibody
3.3.4. TiO2 nanodelivery of pharmacological agents
3.4. Parameters measured
3.4.1. Physiological parameters
3.4.2. Physiological variables
3.4.3. Blood-brain barrier permeability
3.4.3.1. Albumin immunohistochemistry
3.4.4. Cerebral blood flow
3.4.5. Brain edema formation
3.5. Behavioral functions
3.5.1. Rota Rod treadmill
3.5.2. Immobility during forced swimming 4.1.2. Physiological variables in MPTP model of PD
4.1.2.1. Mean arterial blood pressure
4.1.2.2. Arterial pH
4.1.2.3. Arterial PaCO2
4.1.2.4. Arterial PaO2
4.1.2.5. Heart rate
4.1.2.6. Respiration rate
4.1.3. Behavioral parameters in MPTP model of PD
4.1.3.1. Rota-Rod performance
4.1.3.2. Forced swimming immobility
4.1.4. Biochemical parameters of MPTP model of PD
4.1.4.1. Tyrosine hydroxylase enzyme
4.1.4.2. Dopamine
4.1.4.3. DOPAC
4.1.5. Hallmarks of biomarkers in MPTP model of PD
4.1.5.1. ASNC
4.1.5.2. p-tau

Contents:
1. The extended evolutionary synthesis and addiction: the price we pay for adaptability
2. Cross-talk between the epigenome and neural circuits in drug addiction
3. Addiction: a dysregulation of satiety and inflammatory processes
4. Corticostriatal plasticity, neuronal ensembles, and regulation of drug-seeking behavior
5. Paraventricular thalamus: gateway to feeding, appetitive motivation, and drug addiction
6. Functional roles of orexin/hypocretin receptors in reward circuit
7. Differential modularity effects of cocaine on marmoset monkey recognition memory
8. Using the research domain criteria (RDoC) to conceptualize impulsivity and compulsivity in relation to addiction
9. Addictive behaviors: why and how impaired mental time matters?
10. Neuroscience-informed psychoeducation for addiction medicine: a neurocognitive perspective
Index.

Contents:
Conventional morphologic imaging : MRI remains the workhorse
Benjamin Cohen, Inna Nutanson, and Girish M. Fatterpekar
Response assessment in neuro-oncology / Tom Mikkelsen and Tobias Walbert
Going beyond the conventional morphologic imaging : an overview of functional imaging techniques / Marco Essig and Cem Calli
Perfusion imaging : DSC MR perfusion / Marco Essig, Joseph Puig Alcantara, and Cem Cali
Perfusion imaging : dynamic contrast enhanced T1-weighted MRI (DCE-MRI) perfusion / David Fussell and Robert J. Young
Perfusion imaging : arterial spin labeling / S. Ali Nabavizadeh, Suyash Mohan, Jeffrey M. Pollock
Perfusion imaging : CT perfusion / Brent Griffith and Rajan Jain
Diffusion weighted imaging for gliomas / Benjamin M. Ellingson, Bryan Yoo, and Whitney B. Pope
Diffusion tensor imaging / Bram Stieltjes and Peter Neher
Functional MRI and diffusion tensor imaging with tractography / Anna Knobel and Robert J. Young
Metabolic imaging : MR spectroscopy / Isabella Björkman-Burtscher and Pia C. Sundgren
Molecular imaging : PET and SPECT / Asim K. Bag and Samuel E. Almodóvar
It's not just the tumor : treatment effects / Brent Griffith and Rajan Jain
It's not just the tumor : CNS paraneoplastic syndromes and cerebrovascular complications of cancers / Prashant Nagpal and Rajan Jain
Image guided neurosurgery : intraoperative MRI / Ian Y. Lee
On the horizon : ultra-high-field MR / Steffen Sammet and Alexander Radbruch
On the horizon : tumor genomics / Rivka R. Colen, Faisal Tai, and Pascal O. Zinn
On the horizon : going beyond the conventional MR contrast agents / Josep Puig and Wilson B. Chwang
On the horizon : molecular imaging / Sanath Kumar, Meser M. Ali, and Ali Syed Arbab.

Contents:
Brain tumor imaging
MR imaging of brain tumors
MR spectroscopic imaging
MR perfusion imaging
Diffusion-weighted methods
Advanced MR methods in differential diagnosis of brain tumors
PET imaging of brain tumors
Advanced imaging modalities and treatment of gliomas: radiation therapy
Advanced imaging modalities and treatment of gliomas: neurosurgery
Future methods in tumor imaging.

Summary: This book is a comprehensive and up-to-date compendium of all aspects of brain tumors in children. After introductory chapters on the epidemiology of brain tumors, the book will provide readers with state-of-the art chapters on the principals of radiation therapy, neurosurgery and neuroimaging. Subsequent chapters discuss the biology and treatment of specific types of brain tumors. The concluding chapters present critical information relevant to survivorship, neurocognitive and other late effects, and the global challenges to better diagnosis and treatment of brain tumors in children. This book is co-authored by experts in the treatment of pediatric brain tumors. All of the authors are internationally recognized authorities and they offer an evidence-based consensus on the biology and treatment of brain tumors. This handbook has far-reaching applicability to the clinical diagnosis and management of brain tumors in children and will prove valuable to specialists, generalists and trainees alike.

Summary: "Topics addressed at the Symposium included the cellular basis of neurodegeneration, memory systems and aging, neural circuits of anxiety, addiction circuits and treatment frontiers, sleep and sleep disorders,hormonal regulation and mood disorders, cortico-striatal circuits in perception and action, deep brain stimulation for psychiatry, computational psychiatry, development of social cognition, restoration of vision, brainmachine interfaces, and new techniques for human brain manipulation."--Foreword.

Summary: This illuminating and comprehensive work offers readers a thorough and detailed perspective of brainstem surgery as well as state-of-the-art discussion on the diagnosis and management of related pathologies. Hailing from around the globe and currently practicing in various countries in Asia, Europe, and North America, the expert authors of this work represent a wide range of disciplines and experiences, providing a comprehensive, interdisciplinary overview of brainstem surgery. Indeed, brainstem pathologies remain the most challenging to manage surgically due to the high eloquence and the deep and hidden location of the brainstem, turning surgical treatment of brainstem pathologies into one of the most complex and demanding fields in neurosurgery. This vital book guides readers through this very complex anatomical territory in which any pathology leads to grave consequences. Taking readers through the depth of the complex architecture of the brainstem in the clinical context, and emphasizing the evidence-based treatment of different brainstem pathologies while also reviewing what the future holds for the management of these pathologies, the book presents a review of state-of-the-art preoperative assessment modalities and surgical. The book covers brainstem-related pathologies from infancy to adulthood, and the text is enriched with diagnostic and surgical images that cover almost all types of brainstem lesions. The book is written in a way that neurosurgery specialists and fellows will feel comfortable navigating throughout its contents, and the enthusiastic neurosurgery resident will find this book to be a valuable guide. A major contribution to the clinical literature, Brainstem Tumors: Diagnosis and Management will also serve as a reference for anyone involved in the treatment of patients suffering from brainstem pathologies, including medical team members such as adult and pediatric neurosurgeons, neurologists, neurooncologists, residents and fellows, clinical neuropsychologists, electrophysiologists, neuroradiologists, and medical students who have a passion to learn about the assessment and surgical management of patients with brainstem diseases.

Contents:
Chapter 1: History of Brainstem Glioma Surgery
Chapter 2: Anatomy of the Brainstem
Chapter 3: Imaging for Brainstem Lesions
Chapter 4: Clinical Presentation and Assessment for Brainstem Tumors
Chapter 5: Intraoperative Neurophysiological Monitoring during Brainstem Surgery
Chapter 6: Low-grade Pediatric Brainstem Gliomas
Chapter 7: High-grade Tumors of the Brainstem (Except DIPG)
Chapter 8: Diffuse Midline Gliomas
Diffuse Intrinsic Pontine Glioma
Chapter 9: Surgery for Vascular Lesions of the Brainstem
Chapter 10: Inflammatory and Infectious Lesions of the Brainstem
Chapter 11: Surgical Approach to Mesencephalic (Midbrain) Tumors
Chapter 12: Surgical Approach to Pontine Tumors
Chapter 13: Surgical Approach to Medullary Tumors
Chapter 14: Radiation and Chemotherapy for Brainstem Tumors
Chapter 15: Future Therapies for Malignant Brainstem Tumors.

Summary: This is the first volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, especially those with certain disease conditions. Over 150 well recognized and respected contributors have come together to compile these up-to-date and well-referenced works. The volumes will serve the reader as the benchmarks in this complex area of interrelationships between dietary protein intakes and individual amino acid supplementation, the unique role of the branched chain amino acids in the synthesis of brain neurotransmitters, collagen formation, insulin and glucose modulation and the functioning of all organ systems that are involved in the maintenance of the body's metabolic integrity. Moreover, the physiological, genetic and pathological interactions between plasma levels of branched chain amino acids and aromatic amino acids are clearly delineated so that students as well as practitioners can better understand the complexities of these interactions. Branched Chain Amino Acids in Clinical Nutrition: Volume 1 covers basic processes at the cellular level, inherited defects in branched chain amino acid metabolism, and experimental models of growth and disease states.

Contents:
Part I. Basic Processes at the Cellular Level
1. Impact of dietary essential amino acids in man
2. Metabolism of BCAAs
3. The cytosolic and mitochondrial branched chain aminotransferase
4. Isoleucine, PPAR and uncoupling proteins
5. Leucine as a stimulant of insulin
6. Effects of leucine and isoleucine on glucose metabolism
7. Hypothalamic leucine metabolism in the regulation of liver glucose metabolism
8. Leucine and resveratrol: experimental model of sirtuin pathway activation
9. Branched chain amino acids and blood ammonia
10. Use of 2H3-leucine to monitor apoproteins
Part II. Inherited Defects in Branched Chain Amino Acid Metabolism
11. Branched chain amino acid oxidation disorders
12. Branched chain amino acids and maple syrup urine disease
13. Mental retardation and isoleucine metabolism
14. Anorexia and valine-deficient diets
Part III. Experimental models of growth and disease states: Role of Branched Chain Amino Acids
15. Leucine and fetal growth
16. Enteral leucine and protein synthesis in skeletal and cardiac muscles
17. Use of branched chain amino acids granules in experimental models of diet-induced obesity
18. Experimental models of high fat obesity and leucine supplementation
19. Branched chain amino acids in experimental models of amyotrophic lateral sclerosis
20. Leucine and ethanol oxidation
21. Isoleucine, leucine and their role in experimental models of bladder carcinogenesis.

Summary: This is the second volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, especially those with certain disease conditions. Over 150 well recognized and respected contributors have come together to compile these up-to-date and well-referenced works. The volumes will serve the reader as the benchmarks in this complex area of interrelationships between dietary protein intakes and individual amino acid supplementation, the unique role of the branched chain amino acids in the synthesis of brain neurotransmitters, collagen formation, insulin and glucose modulation and the functioning of all organ systems that are involved in the maintenance of the body?s metabolic integrity. Moreover, the physiological, genetic and pathological interactions between plasma levels of branched chain amino acids and aromatic amino acids are clearly delineated so that students as well as practitioners can better understand the complexities of these interactions. Branched Chain Amino Acids in Clinical Nutrition: Volume 2 covers the role of branched chain amino acids in healthy individuals, and branched chain amino acid status in disease states, liver diseases, and supplementation studies in certain patient populations.

Contents:
Part I. Role of Branched Chain Amino Acids in Healthy Individuals
1. Tolerability of leucine
2. Leucine-protein supplemented recovery and exercise
3. Use of whey and leucine on muscle
4. Branched chain amino acids and muscle atrophy protection
5. Role of branched chain amino acids in cellular and organ damage: the prognostic significance of the preoperative branched chain amino acid to tyrosine ratio
Part II. Branched Chain Amino Acids: Status in Disease States
6. Branched chain amino acids in heart failure
7. Mitochondrial tRNA valine in cardiomyopathies
8. Branched chain amino acids on psychomotor performance
9. The branch chain amino acids in the context of other amino acids in traumatic brain injury
10. Branched chain amino acids in chronic obstructive pulmonary disease
Part III. Branched Chain Amino Acids and Liver Diseases
11. Identification of branched chain amino acids; underlying molecular pathways using transcriptomic analysis: application to cirrhosis
12. Branched chain amino acids supplementation and plasma albumin
13. Late evening snack, branched chain amino acids and cirrhosis
14. Branched chain amino acids and organ transplantation
15. Basic aspects in prevention of post-transplant bacteremia by branched chain amino acids
16. Branched chain amino acids and postoperative quality of life
Part IV. Branched Chain Amino Acid Supplementation Studies in Certain Patient Populations
17. Leucine-protein functional adaptation in the clinical setting
18. Branched chain amino acids supplementation and glycemic control
19. Leucine supplementation and insulin resistance
20. Weight loss and branched chain amino acids and their metabolites
21. Branched chain amino acid cocktails and skin
22. Branched chain amino acids in inherited muscle disease: the case of Duchhene muscular dystrophy
23. Use of branched chain amino acids (BCAA) during radiotherapy
24. Oral branch chain amino acids and encephalopathy
25. Web based resources, and suggested readings.

Summary: "Those familiar with previous editions will recognize editors and authors Drs. William Brant and Clyde Helms, who developed the concept of Fundamentals of Diagnostic Radiology 30 years ago. For this fifth edition, Bill has updated his introductory chapter on diagnostic imaging methods and contributed updated material on gastrointestinal and genitourinary radiology and ultrasound. Clyde has updated his section on Musculoskeletal Imaging along with Dr. Emily Vinson, Division Chief of Musculoskeletal Imaging at Duke University Medical Center, who now joins as an editor of Fundamentals. Drs. Erik Gaensler and Jerome Barakos have returned to edit the revised Neuroradiology section. Dr. Jeffrey Klein, along with colleagues from the University of Vermont Medical Center, provides an updated section on Chest Radiology and is now a senior editor of Fundamentals of Diagnostic Radiology"--Provided by publisher.

Contents:
Sect. I: Basic principles
Sect. II: Neuroradiology
Sect. III: Chest
Sect. IV: Breast radiology
Sect. V: Cardiac radiology
Sect. Vi: Vascular and interventional radiology
Sect. VII: Gastrointestinal tract
Sect. VIII: Genitourinary tract
Sect. IX: Ultrasonograpy
Sect. X: Musculoskeletal radiology
Sect. XI: Pediatric radiology
Sec.t XII: Nuclear radiology.

Summary: Global population is mounting at an alarming stride to surpass 9.3 billion by 2050, whereas simultaneously the agricultural productivity is gravely affected by climate changes resulting in increased biotic and abiotic stresses. The genus Brassica belongs to the mustard family whose members are known as cruciferous vegetables, cabbages or mustard plants. Rapeseed-mustard is world's third most important source of edible oil after soybean and oil palm. It has worldwide acceptance owing to its rare combination of health promoting factors. It has very low levels of saturated fatty acids which make it the healthiest edible oil that is commonly available. Apart from this, it is rich in antioxidants by virtue of tocopherols and phytosterols presence in the oil. The high omega 3 content reduces the risk of atherosclerosis/heart attack. Conventional breeding methods have met with limited success in Brassica because yield and stress resilience are polygenic traits and are greatly influenced by environment. Therefore, it is imperative to accelerate the efforts to unravel the biochemical, physiological and molecular mechanisms underlying yield, quality and tolerance towards biotic and abiotic stresses in Brassica. To exploit its fullest potential, systematic efforts are needed to unlock the genetic information for new germplasms that tolerate initial and terminal state heat coupled with moisture stress. For instance, wild relatives may be exploited in developing introgressed and resynthesized lines with desirable attributes. Exploitation of heterosis is another important area which can be achieved by introducing transgenics to raise stable CMS lines. Doubled haploid breeding and marker assisted selection should be employed along with conventional breeding. Breeding programmes aim at enhancing resource use efficiency, especially nutrient and water as well as adoption to aberrant environmental changes should also be considered. Biotechnological interventions are essential for altering the biosynthetic pathways for developing high oleic and low linolenic lines. Accordingly, tools such as microspore and ovule culture, embryo rescue, isolation of trait specific genes especially for aphid, Sclerotinia and alternaria blight resistance, etc. along with identification of potential lines based on genetic diversity can assist ongoing breeding programmes. In this book, we highlight the recent molecular, genetic and genomic interventions made to achieve crop improvement in terms of yield increase, quality and stress tolerance in Brassica, with a special emphasis in Rapeseed-mustard.

Contents:
1 Utilization of rapeseed-mustard genetic resources for Brassica improvement
2 Recent advances in cytoplasmic male sterility (CMS) in crop Brassicas
3 Ancient and recent Polyploid evolution in Brassicas
4 Production and application of doubled haploid in Brassica improvement.-5 Tissue culture-mediated biotechnological advancements in genus Brassica
6 Genomics for Brassica quality improvement
7 Biofortification of Brassica for quality improvement.-8 Genetics and Genomic Approaches for Disease Resistance in Brassicas
9 Arsenic toxicity and molecular mechanism of arsenic tolerance in different members of Brassicaceae
10 Transgenic approaches for Brassica improvement
11 Genetic diversity studies in Indian mustard using molecular markers.

Summary: This book presents comprehensive information on genetics, genomics and breeding in Brassica oleracea, an agriculturally important species that includes popular vegetable crops such as cabbage, cauliflower, broccoli, Brussels sprouts, kale, collard greens, savoy, kohlrabi, and gai lan. The content spans whole genome sequencing, assembly and gene annotation for this global vegetable species, along with molecular mapping and cloning of genes, physical genome mapping and analyses of the structure and composition of centromeres in the B. oleracea genome. The book also elaborates on asymmetrical genome evolution and transposable elements in the B. oleracea describes gene family differentiation in comparison to other Brassica species and structural and functional genomic resources and data bases developed for B. oleracea. Useful discussions on the impact of genome sequencing on genetic improvement in the species are also included.

Contents:
Economic/Academic importance
Background of the sequencing initiatives
Molecular mapping and cloning of genes and QTLs
Physical mapping of the genome
Whole genome sequencing and assembling
Structure and composition of centromere in Brassica genome
Genome annotation
Gene loss
Alternative splicing
Gene conversion
Gene family differentiation in Brassica species
Glucosinates
R genes variations after triplication
Structural & functional genomic resources developed
Impact on plant breeding and crop improvement
Data bases
Future prospects.

Summary: The entire range of the developmental process in plants is regulated by a shift in the hormonal concentration, tissue sensitivity and their interaction with the factors operating around the plants. Phytohormones play a crucial role in regulating the direction of plant in a coordinated fashion in association with metabolism that provides energy and the building blocks to generate the form that we recognize as a plant. Out of the recognized hormones, attention has largely been focused on Auxins, Gibberellins, Cytokinins, Abscisic acid, Ethylene and more recently on Brassinosteroids. In this book we are providing the information about a brassinosteroids that again confirm its status as phytohormones because it has significant impact on various aspects of the plant life and its ubiquitous distribution throughout the plant kingdom. Brassinosteroids are generating a significant impact on plant growth and development, photosynthesis, transpiration, ion uptake and transport, induces specific changes in leaf anatomy and chloroplast structure. This book is not an encyclopedia of reviews but includes a selected collection of newly written, integrated, illustrated reviews describing our knowledge of brassinosteroids. The aim of this book is to tell all about brassinosteroids, by the present time. The various chapters incorporate both theoretical and practical aspects and may serve as baseline information for future researches through which significant development is possible. It is intended that this book will be useful to the students, teachers and researchers, both in universities and research institutes, especially in relation to biological and agricultural sciences.

Summary: Prepare for your ABFM boards - find your weak spots and eliminate them now! Handy in print and as an eBook, Bratton's Family Medicine Board Review is the essential practice test for those facing the ABFM exams. Opening with the basic requirements of the ABFM Board certification process, it provides crucial background information on all three AFBM exams and their formats, describes a typical exam day, and offers excellent test-taking advice{u2014}taking the mystery out of the exam process.

Contents:
Care of the adult patient
Care of children & adolescents
Care of the female patient (including maternity care)
Mental health/community health
Emergent and surgical care
Care of the elderly patient
Pictorial atlas.

Summary: The "skin" classic in a completely updated new edition. "Braun-Falco's Dermatology " has been extensively revised for the 4th edition and offers an impressive overview of the complete specialist field for the clinically active dermatologist . With an internationally renowned team of authors, the editors have succeeded in presenting dermatology in its clinical breadth and groundbreaking further developments in a comprehensive, precise and practical manner. The unique wealth of excellent illustrations and the clear, concise structure of the chapters are particularly noteworthy. In addition to the printed version, the new edition is also available for the first time in an electronic, continuously updated version. New in the 4th edition: - Current clinical classifications, guidelines and therapeutic concepts for inflammatory dermatoses and skin tumours This book is a must-read for dermatologists, doctors in continuing education and clinicians in general.

Contents:
Basic Principles
Diagnostic Tools
Infectious Diseases: Viruses
Infectious Diseases: Bacteria
Infectious Diseases: Fungi
Infectious Diseases: Sexually Transmitted Diseases
Infectious Diseases: Parasitic Infections
Allergy and Intolerance Reactions
Drug Hypersensitivity
Inflammatory Diseases
Environmental Diseases
Bullous Disorders
Connective Tissue Diseases
Hereditary Disorders
Vascular Diseases
Pigmentary Diseases
Diseases of Adnexal Structures
Regional and Special Disorders
Metabolic Diseases
Tumors
Therapy.

Summary: The standard textbook of Dermatology and Allergy in new edition! The 4th edition of the "Braun-Falco Textbook", an international standard text of dermatology, allergy and sexually transmitted disorders has been thoroughly rewritten and reedited and offers a comprehensive state-of-the-art review of the entire field for clinicians in hospital and private practice. The editors assembled an expert team of authors with outstanding international reputation who present a concise overview of the complete spectrum of dermatology and its groundbreaking progress with particular emphasis on aspects of practical care within the specialty. The treatment recommendations are based on current international guidelines and standards of care, and pay special attention to latest therapeutic progress as well as recent pathophysiological concepts. A special emphasis has been put on a unique array of high quality figures and a clear, easily understandable structure of the respective chapters. Besides the printed version, the new edition is available as a digital version. New aspects of the 4th edition that reflect the tremendous and rapid progress of dermatology include an up to date clinical classification of dermatoses, current guidelines and therapeutic concepts in inflammatory and neoplastic diseases, and dermatological aspects of the new Covid-19 infection. "Braun-Falcos̀ Dermatology" is a must for specialists and trainees in dermatology, and of great value for all physicians who encounter skin diseases in general.

Contents:
Basic Principles
Diagnostic Tools
Infectious Diseases: Viruses
Infectious Diseases: Bacteria
Infectious Diseases: Fungi
Infectious Diseases: Sexually Transmitted Diseases
Infectious Diseases: Parasitic Infections
Allergy and Intolerance Reactions
Drug Hypersensitivity
Inflammatory Diseases
Environmental Diseases
Bullous Disorders
Connective Tissue Diseases
Hereditary Disorders
Vascular Diseases
Pigmentary Diseases
Diseases of Adnexal Structures
Regional and Special Disorders
Metabolic Diseases
Tumors
Therapy.

Contents:
Section 1. Fundamentals of Cardiovascular Disease : Genetics and Personalized Medicine : Evaluation of the Patient.
Section 2. Heart Failure Arrhythmias, Sudden Death, and Syncope.
Section 3. Preventive Cardiology Atherosclerotic Cardiovascular Disease.
Section 4. Diseases of the Heart, Pericardium, and Pulmonary Vascular Bed.
Section 5. Cardiovascular Disease in Special Populations Cardiovascular Disease and Disorders of Other Organs.

Summary: Brave leadership is the essential guide for leaders in today's ever-shifting world. Wherever you are in your leadership journey or if you aspire to be the best leader you can be , then this book is for you. It will help you uncover your barriers to brave, escape overwhelm and frustration and learn to manage stress and anxiety, prepare for high-stakes meetings and conversations, have the influence you want to have, set the direction of your career, connect powerfully, feel more confident, courageous, satisfied, and purposeful, and tap into the want of the people you lead to get the results you need.

Contents:
Part I: What is brave? Who are you as a leader?
A whole new world
Dealing with real
Redefining leadership
Unlocking the want
Barriers to brave. Disappearing genius
What do you see?
Step out of the box
Where are you...really?
Part III. Pushing through to brave. A matter of focus
Bull's eye
Goals are not enough
Action from the inside out
For the sake of what?-- What's your intention?
The magic if
Own your power
Connection is the game
Six steps to prepare for impact
Presenting bravely
Part IV: A brave new world. Own your mess
Cultivating brave
A brave legacy
The brave leadership manifesto
Be a work in progress.

Summary: "From the founder of Khan Academy, the first book written for general audiences on the AI revolution in education, its implications for parenting, and how we can best harness its power for good"-- Provided by publisher.

Contents:
Introduction Let's write a new story together
Part I Rise of the AI tutor. Throwing away the bottle
How to teach everything to everyone
Rise of the AI tutor
Part II Giving voice to the social sciences. Why students write
The future of reading comprehension, where literature comes alive!
AI and creativity
Conversing with history
Part III Empowering the next innovators. Using science to study science
1 + 1 = closing the math gap
Accessing courses that students otherwise would not
The most important subject-matter domain to master
Part IV Better together. Bolstering collaborative learning
AI meets student mental health coaching
The place for parents in AI-based education
Increasing points of connection between parents and their kids
Part V Keeping kids safe. Delivering the facts : the state of bias and misinformation
What about data collection?
AI and the gift of transparency
AI as "guardian angel"
Part VI Teaching in the age of AI. How AI will supercharge teachers and teaching
Dawn of the AI teaching assistant
Helping build alternative education models
Fixing cheating in college
Part VII The global classroom. The global classroom
Economics of AI in education
Part VIII AI, assessments, and admissions. The future of K-12 assessments
The AI of college admissions
Part IX Work and what comes next. Employment in an AI world
How to prepare kids to thrive in the AI-future workplace
Matchmaking between job seekers and employers
Where this leaves us and where it will take us : a call for educated bravery.

Summary: "From the founder of Khan Academy, the first book written for general audiences on the AI revolution in education, its implications for parenting, and how we can best harness its power for good"-- Provided by publisher.

Contents:
Introduction. Let's write a new story together ; Part I. Rise of the AI tutor. Throwing away the bottle ; How to teach everything to everyone ; Rise of the AI tutor
Part II. Giving voice to the social sciences. Why students write ; The future of reading comprehension, where literature comes alive! ; AI and creativity ; Conversing with history
Part III. Empowering the next innovators. Using science to study science ; 1 + 1 = closing the math gap ; Accessing courses that students otherwise would not ; The most important subject-matter domain to master
Part IV. Better together. Bolstering collaborative learning ; AI meets student mental health coaching ; The place for parents in AI-based education ; Increasing points of connection between parents and their kids
Part V. Keeping kids safe. Delivering the facts : the state of bias and misinformation ; What about data collection? ; AI and the gift of transparency ; AI as "guardian angel"
Part VI. Teaching in the age of AI. How AI will supercharge teachers and teaching ; Dawn of the AI teaching assistant ; Helping build alternative education models ; Fixing cheating in college
Part VII. The global classroom. The global classroom ; Economics of AI in education
Part VIII. AI, assessments, and admissions. The future of K-12 assessments ; The AI of college admissions
Part IX. Work and what comes next. Employment in the AI world ; How to prepare kids to thrive in the AI-future workplace ; Matchmaking between job seekers and employers ; Where this leaves us and where it will take us : a call for educated bravery.

Summary: This is the first English-language book dedicated to Brazilian sand flies and their medical importance. No other country has so many species of these haematophagous insects as Brazil and their diversity has reached an astonishing level. The book contains comprehensive chapters, written by Brazilian experts on their regional distribution, their ecology and their importance as vectors of pathogens and parasites. Methods for sampling, processing and preserving phlebotomines are reviewed as are perspectives on surveillance and leishmaniasis vector control. A novel classification is presented whose aim is to help investigators identify the species that they are working with more efficiently.

Contents:
Sand flies : medical importance / Wagner Alexandre Costa and Nataly A. Souza
Phlebotominae (Diptera, Psychodidae) : classification, morphology and terminology of adults and identification of American taxa / Eunice A.B. Galati
Molecular and biochemical markers for investigating the vectorial roles of Brazilian sand flies / Paul D. Ready, Felipe M. Vigoder, and Elizabeth F. Rangel
Regional distribution and habitats of Brazilian phlebotomine species / Gustavo M. de Aguiar and Vanessa R. Vieira
Bionomy : biology of neotropical phlebotomine sand flies / Reginaldo P. Brazil and Beatriz G. Brazil
Biology of the Leishmania-sand fly interaction / Paulo F.P. Pimenta, Vanessa C. de Freitas, Carolina C. Monteiro, Ana Clara M.A. Pires, and Nágila Francinete C. Secundino
Sand fly vectors of American cutaneous leishmaniasis in Brazil / Elizabeth F. Rangel, Ralph Lainson, Bruno M. Carvalho, Simone M. Costa, and Jeffrey J. Shaw
Eco-epidemiology of American visceral leishmaniasis with particular reference to Brazil / Elizabeth F. Rangel, Ralph Lainson, Margarete M.S. Afonso, and Jeffrey J. Shaw
Brazilian phlebotomines as hosts and vectors of viruses, bacteria, fungi, protozoa (excluding those belonging to the genus Leishmania) and nematodes / Jeffrey J. Shaw, Amélia T. de Rosa, Ana Cecilia Cruz, and Pedro Fernando da C. Vasconcelos
Methods for capturing, processing and preserving Phlebotominae / Mauricio Luiz Vilela, Adriana Zwetsch, and Júlia dos S. Silva
Leishmaniasis-vector surveillance and control in Brazil : a challenge to control programs / Ana Nilce S. Maia-Elkhoury, Rafaella Albuquerque, and Oscar D. Salomón.

Contents:
Introduction
Schema therapy: toward a science of relationships
Past tense, present tense: understanding family patterns
Attractions, romance, and schema chemistry
Back to the future
Modes: in the present tense
Mode awareness
Managing the modes
Past tense: managing the parent modes
The "great escape": understanding the coping modes
Meeting the needs of your "inner child"
Mode change
Putting "healthy" back in your adult
A clear path: dealing with conflicts, communication, and decision making
Looking at sex through the eyes of the modes
Affairs
Emotional learning
Epilogue.

Summary: "For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold? As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses--tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it. In THE BREAKTHROUGH, Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step--harnessing the wealth of new information to create modern and more effective patient therapies--is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease. Groundbreaking, riveting, and expertly told, THE BREAKTHROUGH is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history"--Jacket.

Contents:
Patient 101006 JDS
A simple idea
Glimmers in the darkness
Eureka, Texas
The three E's
Tempting fate
The chimera
After the gold rush
It's time
Appendix A: Types of immunotherapies now and upcoming
Appendix B: The breakthrough, in brief
Appendix C: A brief anecdotal history of disease, civilization, and the quest for immunity.

Contents:
Imaging the Symptomatic Breast in the Pediatric, Young, Pregnant, Lactating, and transgender patient
Imaging of the symptomatic breast
Imaging of the symptomatic Male breast
Imaging in the management of women with an elevated risk for Breast cancer
Multidisciplinary approach in the management of a breast cancer patient
Screening for Breast cancer
Emerging Technologies in Breast cancer screening and Diagnosis
Non-Obstetric Complications in Pregnancy: Role of Imaging
Pelvic Mass: Role of Imaging in the diagnosis and Management
Post-menopausal bleeding: Role of Imaging in the diagnosis and Management
Pelvic Floor Dysfunction: Role of imaging in diagnosis and management
Female Infertility: Role of Imaging in the diagnosis and Management
Recurrent Urinary Tract infections: Role of Imaging
Health Economics in Women's Imaging.

Summary: Written by internationally acclaimed specialists, Breast, Endocrine and Surgical Oncology provides pertinent and concise procedure descriptions spanning benign and malignant problems and minimally invasive procedures. Complications are reviewed when appropriate for the organ system and problem, creating a book that is both comprehensive and accessible. Stages of operative approaches with relevant technical considerations are outlined in an easily understandable manner. The text is illustrated throughout by photographs that depict anatomic or technical principles. Forming part of the series, Surgery: Complications, Risks and Consequences, this volume Breast, Endocrine and Surgical Oncology provides a valuable resource for all general surgeons and residents in training. Other healthcare providers will also find this a useful resource.

Contents:
Breast Surgery
Thyroid and Parathyroid Surgery
Adrenal Gland Surgery
Lymphatic Surgery
Splenic Surgery
Specialised Cancer Procedures and Surgery.

Contents:
The process of breast augmentation / William P. Adams Jr
Patient education / William P. Adams Jr. and Christy Aguilar
Tissue-based planning / William P. Adams Jr
Three-dimensional imaging / Kevin H. Small and Jason Roostaeian
Shaped versus round implants / Patrick Mallucci and Paulo Montemurro
Biofilms and breast implants : how science guides us to do the best for our patients / W. Louis F. Wessels, Karen Vickery, and Anand K. Deva
Dual-plane breast augmentation / William P. Adams Jr
The inframammary approach and the dual-plane pocket / William P. Adams Jr
The transaxillary approach / Louis L. Strock
Periareolar mastopexy augmentation / Ruth Graf, Maria Cecília Closs Ono, and Priscilla Balbinot
Infra-areolar zigzag augmentation mammaplasty / Ruth Graf, Priscilla Balbinot, and Daniele Tanuri Pace
Breast augmentation with large volume fat grafting / Ran Y. Stark, Louis P. Bucky, and Daniel A. Del Vecchio
Revision breast augmentation / Bradley P. Bengtson and Steven Teitelbaum
Postoperative management / William P. Adams Jr. and Louis L. Strock.

Summary: Breast Cancer: A New Era in Management provides a compendium of succinct analysis of the many facets involved in the present day management of the breast cancer patient. The text provides the clinician or student with basic foundational knowledge in the rapidly expanding areas of expertise that are required for both the diagnosis and treatment of the breast cancer patient. Each topic, whether diagnostic or therapeutic, is presented in a straightforward fashion incorporating as part of each topic a description of the historical clinical landmarks leading to the present day, their present day position in the care of the breast patient, and finally, an assessment of possible future application and adaptation in clinical practice. Emphasis is placed on clear and concise explanations of each topic presented in stepwise fashion from fundamental elements to the more complex. Breast Cancer: A New Era in Management will act as a ready reference for the practicing surgeon and students seeking practical information on a particular clinical topic or scenario.

Contents:
Risk Assessment
The impact of mammography screening on the diagnosis and management of early phase breast cancer
The Sick Lobe Syndrome
Lobar Ultrasonic Breast Anatomy
The Surgical Approach to the Sick Lobe
Ultrasound Guided Breast Biopsy Tissue Sampling: Technique And Breast Ultrasound Characteristics Of Benign And Malignant Lesions
Role of Stereotaxis in Diagnosis and Treatment of Breast Tumors
Breast MR for Treatment Planning
Digital Breast Tomosynthesis
Interstitial Laser Therapy (Ilt) Of Breast Tumors
Cryoablation For Breast Cancer
RF Therapy
HiFrequency Ultrasound
High Risk Lesions
Ductal Carcinoma In Situ of the Breast
The Surgical Management of Invasive Breast Cancer
Surgical Management of the Axilla
Radiotherapy of the Breast
Systemic Therapy.

Contents:

v. 1. Procedures.

Summary: The book provides detailed information on breast cancer and covers all the aspects of this rapidly spreading disease, such as applied anatomy and physiology, causative factors, various Investigations to reach a concise, definitive and complete diagnosis. The management of breast cancer involves multi-modality treatment and the book describes all the modalities in a very clear manner. It also discusses in a very lucid and practical way. the multi-prong treatment that the patient requires. Additionally, the book covers lesser-known areas of the subject like rehabilitation, management of lymphoedema, Extravasation of chemo-Infusion, organization of breast cancer management group, breast cancer awareness and patient education, follow up of the patient, and psychological support to these patients who have undergone mutilation of their organ. Edited by experts the chapters are contributed by renowned onco-sugeons from high volume and reputed centers in India such as, PGIMER, Chandigarh, AIIMS, New Delhi, and TMH, Mumbai among others. The book serves as a useful resource for surgeons, medical oncologists, radiotherapists, pathologists, radiologists and many other specialists interested in the field of breast cancer and actively working in this area. It is useful for practitioners and residents as well as for those who want to learn the different aspects of this disease.

Contents:
Current scenario of breast cancer in India
Applied anatomy for breast cancer
Applied physiology for breast cancer
Aetiopathogenesis and prevention of breast cancer
Classification of breast cancer
Approach to a new suspected patient of of breast cancer, including diagnostic evaluation and staging work up
Cytology for breast cancer
Pathological evaluation of breast cancer
Radiological imaging for breast cancer
PET-CT and total body bone scan for breast cancer
Tumour markers, prognostic factors and their interpretation in breast cancer
Management of early breast cancer surgical aspect
Breast cancer surgery under local anaesthesia
Management of locally advanced breast cancer - surgical aspect
Management of late breast cancer (metastatic and recurrent - surgery)
Management of hereditary breast cancer
Role of radiotherapy in breast cancer
Role of chemotherapy in breast cancer
Hormonal and target therapy for breast cancer
Oncoplastic and reconstruction for breast cancer
Management of metastatic breast cancer and palliative care
Management of breast cancer with associated problems
Management of lymphoedema in breast cancer
Management of chemotherapy infusion extravasation in breast cancer
Psychological and psychiatric support to breast cancer patients
Follow up and rehabilitation in breast cancer
Screening, self-examination and awareness in breast cancer
Organization of breast cancer management group.

Contents:
Development, anatomy and physiology of the mammary gland / F. Baum
Tumor formation / F. Baum
Pathology of benign and malignant changes in the breast / J. R'schoff
Non-imaging diagnostics / U. Fischer
Mammography / U. Fischer
Breast ultrasonography / S. Luftner-Nagel
Magnetic resonance imaging (MRI) of the breast / U. Fischer
Imaging of breast lesions / U. Fischer, S. Luftner-Nagel
Breast intervention / F. Baum
Examination concepts / U. Fischer
Surgical treatment of breast cancer / Th. Kahn
Medical treatment of breast cancer / M. Hellriegel, G. Emons
Radiotherapy of breast cancer / C.F. Hess
Management of a diagnostic breast center / F. Baum
Logistics in an interdisciplinary breast center / G. Emons
Counselling techniques and psychosocial support / H. Lorch, A. K'chemann, J. R'schoff.

Summary: This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art therapies and techniques. Further topics to receive detailed consideration include particular conditions requiring multidisciplinary approaches, the investigation of new drugs and immunological agents, lifestyle and psychological aspects, and biostatistics and informatics. The book will be an excellent reference for practitioners, interns and residents in medical oncology, oncologic surgery, radiotherapy, pathology, and human genetics, researchers, and advanced medical students.

Summary: "Because most cancer care is delivered in the community setting, Breast Cancer, edited by Dr. James L. Weese, looks at the management of breast cancer through the lens of multidisciplinary pathways focused on evidence-based, real-world care of breast cancer patients in the community. A multidisciplinary team of expert authors provides state-of-the-art guidance from the perspective of community practitioners using an evidence-based model, clearly showing the thought processes used to make treatment decisions in today's breast cancer management"-- publisher's description.

Contents:
Breast Cancer in the Community
Multidisciplinary Team Approach to the Management of Breast Cancer
Oncology Nurse Navigation in the Care of Breast Cancer
Breast Cancer Screening
Outcomes and Quality Indicators
Evaluation and Treatment in the Underserved Community
Contemporary Surgical Approaches to Breast Cancer
Radiation Therapy
Systemic Therapy for Breast Cancer
Breast Cancer Pathology for Precision Oncology
Physical Therapy for Patients With Breast Cancer
Nutrition
Breast Cancer Survivorship in Community Oncology Practice
Breast Cancer Palliative Care
Genetics and Prevention
Coping With the High Cost of Cancer
Expectations for the Future.

Contents:
Epidemiology.- Managing breast cancer in young women
Impact of breast cancer treatment on fertility.- Fertility preservation and ART
Breast cancer during pregnancy.- Pregnancy after breast cancer
Reproductive issues in BRCA mutation carriers.

Contents:
Cascade of disability in breast and gynecologic cancer
Practice implementation, clinical assessment, and outcomes measurement
Exercise while living with breast and gynecological cancers
Cancer-related fatigue in breast and gynecologic cancers
Nutritional rehabilitation of breast and gynecologic cancer patients
A comprehensive approach to psychosocial distress and anxiety in breast and gynecological cancers
Prehabilitation in breast and gynecologic oncology
Systemic therapy for the treatment of breast cancer
Principles of radiation therapy in breast cancer
Breast cancer surgery
Reconstructive surgery and postoperative care for breast cancer
Rehabilitation of the cancer patient with skeletal metastasis
Shoulder dysfunction in breast cancer
Role of interventional pain management in breast cancer
Aromatase inhibitor musculoskeletal syndrome
Systemic therapy for gynecologic malignancies
Principles of radiation therapy in gynecologic cancer
Surgical gynecologic oncology
Pelvic floor dysfunction in gynecologic cancer
Cancer-related cognitive impairment: diagnosis, pathogenesis, and management
Lymphedema in breast and gynecologic oncology
Peripheral nervous system involvement in breast and gynecologic cancers
Inpatient rehabilitation for breast and gynecologic cancer patients
Palliative care and symptom management in breast and gynecological cancers
Fertility preservation in the setting of breast and gynecologic cancers and cancer treatment
Oncology massage therapy in breast and gynecologic cancers.

Summary: Breast Cancer Biology for the Radiation Oncologist is the first textbook of its kind devoted to describing the biological complexities of breast cancer in a way that is relevant to the radiation oncologist. Radiation Oncology has long treated breast cancer as a single biological entity, with all treatment decisions being based on clinical and pathologic risk factors. We are now beginning to understand that biological subtypes of breast cancer may have different risks of recurrence as well as different intrinsic sensitivity to radiotherapy. Multi-gene arrays that have for years been used to predict the risk of distant recurrence and the value of systemic chemotherapy may also have utility in predicting the risk of local recurrence. Additionally, the targeted agents used to treat breast cancer may interact with radiotherapy in ways that can be beneficial or undesirable. All of these emerging issues of central importance to radiation oncologists are extensively discussed in this book, and practical treatment recommendations based on available clinical evidence are presented whenever possible.

Contents:
Biological subtypes of breast cancer
Oncogene amplification and Herceptin
Current clinical use of genetic profiling
Biology of DCIS and progression to invasive disease
Cancer Stem Cells and Radiotherapy
Genetic basis of normal tissue radiosensitivity and late toxicity
Genetic syndromes and radiotherapy in breast cancer
Experimental therapies in breast cancer.

Summary: Breast cancer is a disease requiring multidisciplinary management including surgery, medical and radiation oncology, radiology, pathology, nuclear medicine, genetic counseling, and psychological support. Each member of the team needs to be updated continuously on breast cancer treatment because of its rapidly changing nature. From the diagnostic procedures to operations and even in metastatic stages of breast cancer, surgeons play an essential part in multidisciplinary teams. After standard surgical options, oncoplastic breast surgery is rapidly becoming one of the most important surgical topics that should be learned by attending surgeons. The idea of writing this book stemmed from a collaboration between the European Academy of Senology (EAoS), European Institute of Oncology (IEO), Euro-Asian Society of Mastology (ESOMA), and SENATURK (Turkish Academy of Senology), which have been working together to promote better training in breast care for professionals. The book offers invaluable support for breast surgeons by covering critical and essential information in senology. It will also greatly benefit the other members of multidisciplinary teams, surgery residents, gynecologists, and plastic and reconstructive surgeons.

Contents:
I INTRODUCTION
1 History of the Breast Surgery
2 Milestone Studies in the Breast Surgery
3 Essential Anatomy
4 Breast Cancer Genetics
5 Molecular Classification of the Breast Cancer
6 Basic Pathology
7 Risk & Management Strategies
8 Quality Issues & Physician Awareness
II BEFORE SURGERy
9 Patient Assessment, Documentation and Clinical Staging
10 Imaging
11 Interventional Radiology
12 Treatment-Directive Pathology
13 Multidisciplinary Meeting
14 Primary / Neoadjuvant Treatments
15 Decision-Making / Operative Planning
16 Breast
17 Axilla
18 Loco-Regional Recurrences.-19 Distant metastases
III OPERATING ROOM & SURGERY
20 Situation awareness, communication and teamwork in the Operating Room
21 Breast conserving and oncoplastic surgery targeting oncoplastic in breast cancer
22 Standard breast conserving surgery
23 Level I therapeutic mammoplasty
24 Level II therapeutic mammoplasty: Round block, Batwing (Omega), Racquet techniques
25 Inferior pedicle mammoplasty
26 Superior pedicle mammoplasty
27 Le-Jour, Vertical Scar & Grisotti techniques
28 L-plasty, J-plasty, V-mammoplasty
29 Latissimus dorsi flap reconstruction
30 Mastectomy-Standard/Skin Sparing/Smiley type
31 Whole breast reconstruction
32 Implant-based reconstruction
33 Autologous tissue-based
34 Symmetrisation
35 Augmentation Mastopexy
36 Reduction mammoplasty
37 Fat grafting in breast reconstruction
38 Technical details, purification, the contraindications, complications and cosmetic results of the technique
39 Nipple-areola reconstruction
40 Lymphatic surgery
41 Level I-II (+) III axillary dissection
42 Sentinel lymph node biopsy
43 Sentinel lymph node biopsy in special conditions
44 Lympho-venous bypass & Lymphoid tissue transfer
IV AFTER SURGERY
45 Immediate Patient Care
46 Short-Term Complications & Management
47 Planning Adjuvant Treatment
48 Radiation Treatment
49 Systemic Treatments
50 Follow-up & Long-Term Patient Care
51 Long-Term Complications & Management
52 Judicial Issues
V ORPHAN ISSUES
53 Inflammatory breast cancer
54 Male breast cancer
55 Occult Breast Cancer
56 Breast Cancer in older women.

Summary: This contributed book covers all aspects concerning the clinical scenario of breast cancer in young women, providing physicians with the latest information on the topic. Young women are a special subset of patients whose care requires dedicated expertise. The book, written and edited by internationally recognized experts who have been directly involved in the international consensus guidelines for breast cancer in young women, pays particular attention to how the disease and its planned treatment can be effectively communicated to young patients. Highly informative and carefully structured, it provides both theoretical and practice-oriented insight for practitioners and professionals involved in the different phases of treatment, from diagnosis to intervention, to follow-up - without neglecting the important role played by prevention.

Contents:
Epidemiology
Age and tumour biology
Imaging to improve diagnosis of breast cancer in young women
Establishing a program for young women at high risk for breast cancer
Loco-regional management of hereditary breast cancer
Systemic therapies of young breast cancer patients at high genetic risk
SURGICAL MANAGEMENT OF BREAST CANCER IN YOUNG WOMEN
Radiation therapy: special issues when treating young women with breast cancer
Timing and type of breast reconstruction in young breast cancer patients
Tailoring chemotherapy and biological treatment in young patients with EBC
Endocrine treatment of young patients with EBC
Management of ABC in young women: what's new on endocrine treatment
Breast cancer during pregnancy
Sexual Health & Body Image after Breast Cancer
Fertility preservation and pregnancy after breast cancer
Lifestyle changes and prevention- unique issues for young women
Supportive care and Psycho-oncology issues during and beyond diagnosis and treatment.

Summary: ​This volume covers recent progress in breast cancer research. It explores breast cancer, the factors that make it lethal and current research progress, including stem cells, microRNAs, epigenetics, genomics and some novel signaling pathways​.

Contents:
1. Introduction to breast cancer: The Magnitude of the problem
2. Risk Factors for Breast Cancer
3. Defining the population at elevated risk for Breast Cancer: Risk Models
4. Genetic predisposition and Genetic screening
5. The BRCA patient population
6. Women with benign proliferative breast disease
7. Approach to Imaging
8. Chemoprevention
9. Lifestyle and Breast Cancer
10. Obesity and Inflammation
11. Conclusion/the Future/ Komen Tissue Bank/Clinical Trials.

Summary: The book provides, in a comprehensive yet concise way, essential information to improve the knowledge and skills of all healthcare providers involved in the treatment of patients with breast cancer. The content does not focus on general information that is widely available via different sources, but on technical aspects "hands-on" daily practices and principles of radiation oncology that are not included in other books. Drawing on information taught in courses at e.g. the ESTRO School, as well as the authors broad clinical experience, the respective contributions reflect and share the expertise of leading experts in breast cancer radiation therapy, supported by sound data and evidence. Each chapter includes a short introduction summarizing the evidence in the literature and "pearls" (a short bullet-point summary), and is enriched by tables, figures and illustrations to provide a concise, easy-to-follow and appealing overview. The book, containing also useful electronic supplementary material, will be of interest to a wide range of readers, including radiation oncologists, radiation technicians, medical physicists, and others involved in breast cancer care.

Contents:
Introduction
Quality Management
Management and workflow
Part 1 general
Part 2 radiation therapy preparation
Part 3 radiation therapy delivery
Part 4 after completion of radiation therapy
Part 5 specific technical topics
Part 6 specific disease topics
Part 7 risk assessment and radiation quality assurance.

Contents:
Breast cancer screening : balancing evidence with culture, politics, money, and media
Estimates of screening benefit : the randomized trials of breast cancer screening
Weighing the benefits and harms : screening mammography in the balance
The importance of observational evidence to estimate and monitor mortality reduction from current breast cancer screening
The role of microsimulation modeling in evaluating the outcomes and effect of screening
Challenges in understanding and quantifying overdiagnosis and overtreatment
Challenges and opportunities in the implementation of risk-based screening for breast cancer
Breast cancer screening in the older woman
Screening women in their 40s
Screening for breast cancer in women with dense breasts
Screening women with known or suspected cancer gene mutations
Imaging surveillance of women with a personal history of breast cancer
Evolution of mammography screening : from film screen to digital breast tomosynthesis
Ethical and societal considerations in breast cancer screening
Treatment of screen-detected breast cancer: can we avoid or minimize overtreatment?
Informed and shared decision making in breast screening.

Summary: This book presents the current trends and practices in breast imaging. Topics include mammographic interpretation; breast ultrasound; breast MRI; management of the symptomatic breast in young, pregnant, and lactating women; breast intervention with imaging pathological correlation; the postoperative breast; and current and emerging technologies in breast imaging. It emphasizes the importance of fostering a multidisciplinary approach in the diagnosis and treatment of breast diseases. Featuring more than 800 high-resolution images and showcasing contributions from leading authorities in the screening, diagnosis, and management of the breast cancer patient, Breast Cancer Screening and Diagnosis is a valuable resource for radiologists, oncologists, and surgeons. Mahesh K. Shetty is a Clinical Professor of Radiology at Baylor College of Medicine and the chief physician at the Woman?s Center for Breast Care & MRI at The Woman?s Hospital of Texas.

Contents:
Breast Cancer Genetics and Risk Assessment
Screening for Breast Cancer
Mammography Techniques, Positioning, and Optimizing Image Quality
Digital Mammography and Digital Breast Tomosynthesis
Mammographic Signs of Breast Cancer
Probably Benign Abnormalities of the Breast
Breast Ultrasound
The Basics of Breast MRI
Breast MRI for Diagnosis and Staging of Breast Cancer
Optimizing Mammographic Screening and Diagnosis of Breast Cancer
Imaging of the Symptomatic Breast in the Young, Pregnant, or Lactating Woman
Breast Intervention
Imaging Pathologic Correlation in Breast Imaging
Challenges in Breast Imaging
Staging of Breast Cancer
The Post-Operative Breast
The Multidisciplinary Approach to Breast Cancer Management
Design and Operation of a Comprehensive Breast Care Center
Emerging Technologies in Breast Imaging.

Contents:
1. Introduction
2. Predicting risk of disease recurrence
3. Detection of recurrence: clinical follow-up
4. Detection of recurrence: imaging strategies
5. Follow up of patients with germline mutations in high risk predisposition genes
6. Endocrine therapy
7. Systemic therapies to reduce the risk of recurrence in early breast cancer: new strategies
8. Exercise in breast cancer survivors
9. Dietary components and breast cancer survivorship
10. Identifiying and managing the consequences of treatment for early breast cancer
11. Managing loco-regional complications of breast cancer
12. The role of surgery in breast cancer survivors
13. Management of menopausal symptoms in breast cancer survivors
14. Bone health
15. Fertility
16. Cardiotoxicity in breast cancer survivors
17. Second primary neoplasms following a diagnosis of breast cancer
18. The effects of breast cancer treatments on cognition
19. Psychological issues in breast cancer survivorship
20. Fatigue in breast cancer survivors
Index.

Summary: "Breast Care Certification Review, Second Edition is the ultimate learning package designed to help prepare oncology nurses to become certified in caring for patients with breast cancer. Thoroughly updated to address the 2018 updates to the Certified Breast Care Nurse (CBCN) examination, it provides numerous practice questions with comprehensive answer rationales making it the essential guide for nurses planning to sit for the CBCN examination"--Provided by publisher.

Contents:
Coordination of care
Diagnosis and staging
Treatment modalities : local and systemic
Nursing practice
Psychosocial and spiritual.

Contents:
Fine-needle aspiration cytology : sampling and preparation technique, fixation, and staining
Principles of interpretation
Normal breast
Cytology of inflammatory and reactive changes
Cystic lesions
Epithelial proliferative lesions
Fibroepithelial lesions
Invasive carcinoma
Other breast neoplasms
Assessment of the lymph node status
Ancillary techniques.

Summary: Breast Disease: Comprehensive Management provides a clear, concise source of information in order to make real-life, evidence-based decisions for all aspects of breast disease, both benign and malignant. The volume provides the latest breakthroughs in breast cancer research, ranging from paradigm shifts in the surgical management of the axilla, the changing role of adjuvant and neoadjuvant chemotherapy, the impact of molecular medicine in decision-making and the controversial role of prophylactic mastectomy in our era. Within select chapters, ℓ́ℓHow I do itℓ́ℓ clinical scenarios are supplied and described in very practical terms. Also included at the end of each chapter are synoptic questions with detailed answers, akin to the self-assessment (SESAP) format questions and answers. These questions provide a basis for continuous medical education (CME) for the practicing physician and surgeon, further in surgical oncology and breast surgery, medical oncologists, radiation oncologists, and breast radiologists enhancing a focused approach to the management of breast disease in preparation for the American Board of Surgery certification and re-certification for the general surgeon. This title is of great value to general surgeons, breast surgeons, surgical oncologists, general surgery residents, and fellows

Summary: This first of two fully updated volumes provides an in-depth account of breast disease characteristics, imaging and diagnosis. Covering from breast anatomy and tumor biology to benign and malignant lesions this is an indispensable companion for breast specialists, medical oncologists, radiologists and pathologists. The new edition contains chapters covering nuclear medicine and a chapter explaining biostatistical and epidemiological terms and has been updated to reflect the latest changes in biomarkers and cancer staging. The book explores topics such as epidemiology, risk factors, pathological evaluation of tumors and biopsy techniques. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into pathological and epidemiological aspects of breast disease. Covering both theoretical and practical aspects of breast cancer this is a highly informative and carefully presented book which will appeal to an international audience of breast cancer practitioners.

Contents:
Breast anatomy and physiology
2. Benign diseases of the breast
3. Benign breast tumors
4. Epidemiology, risk factors, and prevention
5. Breast imaging and image-guided biopsy techniques
6. Lobular carcinoma in situ
8. Biology and genetics of breast cancer
9. Clinical aspects of estrogen and progesterone receptros and ERBB2 testing
10. Prognostic and predictive factors of invasive breast cancer
11. Gene arrays, prognosis, and therapeutic interventions
12. Bone marrow micrometastases and circulating tumor cells
13. Pathology of breast cancer
14. Intraoperative pathological examination of breast lesions
15. Fibroepithelial tumors of the breast
16. Mesenchymal tumors of the breast
Index.

Contents:
1. Biopsy techniques in non-palpable or palpable breast lesions
2. Evaluation of patients for metastases prior to primary therapy
3. Staging of breast cancer
4. Surgical treatment of early-stage breast cancer
5. Evaluation of axillary nodes
6. Breast reconstruction
7. Adjuvant systemic therapy: endocrine therapy
8. Adjuvant systemic chemotherapy for HER2-negative disease
9. Adjuvant therapy for HER2-positive early breast cancer
10. Post-mastectomy adjuvant radiotherapy (PMRT)
11. Adjuvant radiation therapy after peroperative chemotherapy
12. Breast-conserving therapy: hypofractionated and conventional whole-breast irradiation and accelerated partial-breast irradiation
13. Preoperative therapy for operable breast cancer
14. Neoadjuvant hormonal therapy in breast cancer
15. Systermic therapy for locally advanced breast cancer
16. Systemic therapy for inflammatory breast cancer
17. Surgical management of operable breast cancer after neoadjuvant systemic therapy
18. Surgical management of locally advanced breast cancer
19. Surgical management of inflammatory breast cancer
20. Occult primary breast cancer with axillary metastases
21. Breast cancer in older women
22. Breast cancer in young women (premenopausal breast cacner)
23. Male breast cancer
24. Breast cancer in pregnancy
25. Paget's disease of the breast
26. Phyllodes tumors of the breast
27. Nonepithelial malignancies of the breast
28. Surveillance of patients following primary therapy
29. Surgery for the primary tumor in patients with de novo stage IV breast cancer
30. Local-regional recurrence after breast-conservation treatment or mastectomy
31. Treatment of metastic breast cancer: chemotherapy
32. Treatment of metastatic breast cancer: chemotherapy
33. Treatment of HER2-overexpressing metastatic breast cancer
34. End-of-life considerations in patients with breast cancer
35. Angiogenesis inhibition in breast cancer
36. Tyrosine kinase inhibitors
37. Neurological metastases
38. Ocular metastases
39. Management of malignant pleural effusions in breast cancer
40. Management of discrete pulmonary nodules
41. Management of isolated liver metastasis
42. Bone-directed therapy and breast cancer: bisphosphonates, monoclonal antibodies, and radionuclides
43. The local management of bone metastases
44. A review of local and systemic therapy in breast cancer
45. Decision pathways in breast cancer management
46. Nursing care and management
47. Psychosocial adaptation during and after breast cancer
48. Breast cancer-related lymphedema (BCRL)
49. Reproductive issues in breast cancer
50. Onco-cardiology for breast cancer
Index.

Summary: This second updated volume on breast cancer provides a comprehensive overview of its clinical management and current therapies. Updated to reflect the changes in breast cancer staging, the progress in immunotherapy approaches, as well as the latest guidelines for therapies, this book brings readers up to speed with the latest therapeutic regimens in breast cancer and provides an in-depth account of current and new therapeutic approaches. The most important phase III trials, high quality meta-analysis, consensus reports and guidelines are extensively discussed in this new edition and provide the reader with the most up-to-date information. Divided in themed parts, the book examines invasive breast cancer, pre-operative systemic therapy surgical management and recurrence among others, thus providing an in-depth account of breast cancer at the clinical stage. Among the themed parts are a section dedicated to special therapeutic problems, such as breast cancer in older women, Paget's disease and phyllodes tumors and a section on supportive and follow-up care. By adopting a multidisciplinary approach to breast cancer, this book is a must-have for breast cancer practitioners. With a high number of colored illustrations and edited by highly experienced clinicians, this work enables readers to gain an interdisciplinary perspective on breast diseases. Contributions from an international team of experts present invaluable insight into clinical practice across different settings. Covering both theoretical and practical aspects of breast cancer, this is a highly informative and carefully presented book which will appeal to an international audience of medical, radiation and surgical oncologists.

Contents:
Part I Invasive Breast Cancer- 1. Biopsy Techniques in Non- palpable or Palpable Breast Lesions
2. Evaluations of Patients for Metastases Prior to Primary Therapy
3. Staging of Breast Cancer
4. Surgical Treatment of Early-Stage Breast Cancer
5. Evaluations of Axillary Nodes
6. Breast Reconstruction
7. Adjuvant Systemic Therapy: Endocrine Therapy
8. Adjuvant Systemic Chemotherapy for HER2-Negative Disease
9. Adjuvant Therapy for HER2-Positive Early Breast Cancer
10. Post-mastectomy Adjuvant Radiotherapy (PMRT)
11. Adjuvant Radiation Therapy After Preoperative Chemotherapy
12. Breast-Conserving Therapy: Hypo fractionated and Conventional Whole-Breast Irradiation and Accelerated Partial-Breast Irradiation
Part II Preoperative Systemic Therapy
13 Preoperative Therapies for Operable Breast Cancer
14 Neoadjuvant Hormonal Therapies in Breast Cancer
15 Systemic Therapies for Locally Advanced Breast Cancer
16 Systemic Therapies for Inflammatory Breast Cancer
Part III Surgical Management of Patient with Preoperative Systemic Therapy- 17 Surgical Management of Operable Breast Cancer After Neoadjuvant Systemic Therapy
18 Surgical Management of Locally Advanced Breast Cancer
19 Surgical Management of Inflammatory Breast Cancer
Part IV Special Therapeutic Problems- 20 Occult Primary Breast Cancer with Axillary Metastases
21 Breast Cancer in Older Women
22 Breast Cancer in Young Women (Premenopausal Breast Cancer)
23 Male Breast Cancer
24 Breast Cancer in Pregnancy
25 Paget's disease of the Breast
26 Phyllodes Tumors of the Breast
27 Nonepithelial Malignancies of the Breast
Part V Evaluation After Primary Therapy and Management of Recurrent Breast Cancer
28 Surveillance of Patients Following Primary Therapy
29 Surgeries for the Primary Tumor in Patients with De Novo Stage IV Breast Cancer
30 Local-Regional Recurrences After Breast-Conservation Treatment or Mastectomy
31 Treatment of Metastatic Breast Cancer: Endocrine Therapy
32 Treatment of Metastatic Breast Cancer: Chemotherapy
33 Treatment of HER2- Overexpressing Metastatic Breast Cancer
34 End-of-Life Considerations in Patients with Breast Cancer
Part VI New Breast Cancer Therapeutic Approaches
35 Angiogenesis Inhibition in Breast Cancer
36 Tyrosine Kinase Inhibitors
37 Immunotherapy
Part VII Site-Specific Therapy of Metastatic Breast Cancer
38 Neurological Metastases
39 Ocular Metastases. Nergiz Dagoglu and Anand Mahadevan
40 Management of Malignant Pleural Effusions in Breast Cancer
41 Management of Discrete Pulmonary Nodules
42 Management of Isolated Liver Metastasis. Abdullah çIægci and Enver èOzkurt
43 Bone-Directed Therapy and Breast Cancer: Bisphosphonates, Monoclonal Antibodies, and Radionuclides Bulent Erdogan and Irfan Cicin
44 The Local Management of Bone Metastases. Levent Eralp and Halil Buldu
Part VIII Review of the Breast Cancer Management
45 A Review of Local and Systemic Therapy in Breast Cancer
46 Decision Pathways in Breast Cancer Management
Part IX Supportive Care in Breast Cancer
47 Nursing Care and Management
48 Psychosocial Adaptation During and After Breast Cancer
49 Breast Cancer-Related Lymphedema (BCRL)
50 Reproductive Issues in Breast Cancer
51 Onco-cardiology for Breast Cancer.

Summary: Designed in a small-format for practical reading and point-of-care setting use, this work presents the most up-to-date concepts on breast diseases. The main objective of this book is to propagate current knowledge of the most frequent breast diseases, being a quick reference, evidence-based manual covering the major clinical scenarios in mastology. The essence of the work can be summarized in the following sentence: "access to maximum content in the least amount of time." The book contains data that will allow readers to understand and treat patients with different complaints and diseases. Each chapter presents a flow chart and a summary of the five major publications on the subject. This is unique in comparison with other books in this medical specialty. Developed by a team of international expert specialists who deal with breast pathologies on a daily basis, the book also includes additional contributions from experienced, renowned professionals in interdisciplinary specialties related to the main area. This book will be of interest to physicians who deal with breast diseases and wish to improve their knowledge through exposure to state-of-the-art data and best practices advice. It is also directed to medical students and residents in training within mastology. -- Provided by publisher.

Contents:
BI-RADS® Classification
Mammography
Ultrasound
Magnetic Resonance Scanning
Nuclear Medicine: PET Scan, Breast Scintigraphy and MBI
Other Imaging Methods
Mammographic Screening
Special Screening Situations
Percutaneous Biopsies
Clinical and Radiological Aspects
Percutaneous Biopsies
Histopathological Aspects
Histopathological Classification of Benign Lesions
Breast Lump
Mastalgia
Nipple Discharge
Gynecomastia
Infectious Breast Diseases
Classification of Proliferative Breast Lesions
Treatment of Proliferative Breast Lesions
Ductal Carcinoma in situ
Identifying High-Risk Patients
Practical Aspects of Genetic Counselling
Prevention: Habits and Behavior
Chemoprevention
Risk Reducing Surgeries
Carcinogenesis and Natural History of Breast Cancer
Histopathological and Immunohistochemical Classification of Breast Cancer
Staging and Prognostic Factors
Epidemiology of Breast Cancer
^Predictive and Prognostic Factors: Genetic Signatures, Adjuvant! and PREDICT
Mastectomy
Conservative Breast Surgery
Surgery of Axillary and Regional Lymph Nodes
Surgery of Non-Palpable Breast Lesions
Handling the Surgical Specimen
Principles of Oncoplastic Breast Surgery
Partial Breast Reconstruction
Pedicles
Breast Reconstruction with Implants
Breast Reconstruction with Myocutaneous Flaps
Lipofilling
Aesthetic Breast Surgery
Early Breast Cancer
Locally Advanced Breast Surgery
Influence of Histologic, Immunohistochemical and Molecular Types on Therapeutics
Inflammatory Carcinoma
Invasive Lobular Carcinoma
Occult Breast Cancer
Paget's Disease
Nonepithelial Breast Cancer
Pregnancy-Associated Breast Cancer
Breast Cancer in Young Patients
Breast Cancer in Elderly Patients
Multifocal, Multicentric and Bilateral Carcinoma
Breast Cancer in Men
Local Relapses
^Breast Cancer in Patients with Previous Aesthetic Surgery
Radiotherapy
Hormonal Therapy
Adjuvant Chemotherapy
Therapy Anti-Her-2
Neoadjuvant Therapy
Other Systemic Treatments
Follow-up
Survivorship
Physical Rehabilitation after Breast Cancer Treatment
Contraception and Infertility
Climateric Treatment after Breast Cancer
Metastatic Breast Cancer
Therapies and Palliative Care.

Summary: It is challenging enough to be able to make a diagnosis in mammography, but the newer standards of care demand more than just providing a diagnosis. This book is an excellent resource to improve the understanding of breast diseases, recognize and manage problems encountered in breast imaging and clinical management of the breast diseases. With forty four chapters, this volume is divided into six sections on screening of breast cancer, imaging modalities, benign breast disorders, interventional procedures, pathological considerations and breast cancer. Breast Diseases: Imaging and Clinical Management is a crisp volume on clinical and multimodality breast imaging with emphasis on interventional procedures, pathology and the entire spectrum of breast cancers.

Summary: "Elastography is a noninvasive imaging technique that detects tumors based on their stiffness compared to normal tissue. It uses ultrasound technology and can be performed during an ultrasound examination of the breast. It can dramatically reduce the number of breast biopsies performed. This book introduces the techniques of breast elastography followed by a detailed description for each of the techniques, highlighting their pros and cons. This is followed by a section on how to perform each of the techniques. The third section discusses the methods of interpretation for each technique, and the final section presents cases studies highlighting the pros and cons of each technique and how to avoid pitfalls in interpretation. It is written to appeal to the beginner as well as the experienced user"--Provided by publisher.

Contents:
Introduction to breast elastography
Principles of elastography
Strain elastography
Shear wave elastography
Combination of shear wave and strain elastography
Clinical cases : benign lesions
Clinical cases : malignant lesions
Clinical cases : other lesions
Future perspective and conclusions.

Contents:
Regulatory/standards of care
Breast cancer screening
Diagnostic breast imaging, breast pathology, and breast imaging findings
Breast intervention
Breast imaging physics and safety.

Contents:
Regulatory/standards of care
Breast cancer screening
Diagnostic breast imaging, breast pathology, and breast imaging findings
Breast intervention
Breast imaging physics and safety.

Summary: This superbly illustrated book provides a thorough, up-to-date overview of diagnostic breast imaging and therapy. Drs. Elizabeth Morris, Michael Fuchsjäger, and Thomas Helbich, three experts in the field, have collaborated with colleagues from their institutions and selected medical centers to share their expertise. The coverage ranges from basic information on imaging technologies and interventional equipment and how to use them optimally to the application of advanced high-end techniques for screening and assessment in any given professional environment. Readers will find clear instruction on the various breast interventional procedures guided by stereotaxis, ultrasound, and magnetic resonance imaging in wide clinical use. The management of patients with ductal carcinoma in situ and high-risk breast cancer is considered separately. Furthermore, the role of minimally invasive therapy is examined, and advice is provided on post-therapy evaluation, including breast implants. A comprehensive diagnostic atlas with hundreds of images completes this volume and addresses the spectrum of various clinical situations.

Contents:
Mammography and Digital Breast Tomosynthesis:Technique
Contrast Enhanced Mammography
Mammography Screening
Stereotactic Guided Breast Interventions
How to Use Breast Ultrasound
Breast Ultrasound: Advanced Techniques
Automated Breast Ultrasound
Ultrasound-Guided Interventions
Breast MRI: Techniques and Indications
Abbreviated Breast MRI: Short and Sweet?
Breast MRI: Multiparametric and Advanced Techniques
MRI-Guided Breast Interventions
Imaging the Axilla
Imaging of Ductal Carcinoma In Situ (DCIS)
Cystic and Complex Cystic and Solid Lesions
High-Risk Lesions of the Breast - Diagnosis and Management
Minimal Invasive Therapy
Post Therapy Evaluation (Including Breast Implants)
Impact and Assessment of Breast Density
Artificial Intelligence in Breast Imaging.

Contents:
Screening mammography
Diagnostic mammography and problem solving
Breast ultrasound
Magnetic resonance imaging of the breast
Skin
Nipple-areolar complex
Major subareolar ducts
Terminal ducts
Lobules
Stroma
The altered breast
The breast in men
Interventional procedures.

Summary: This book covers all the essential aspects of breast imaging necessary for the preparation of MMed, MD, FRCR and FRANZCR exams. The main focus is on mammogram and breast ultrasound along with basics of breast MRI and breast interventions. With the increasing popularity of these qualifying exams among radiology residents in Asia, Great Britain as well as Australia and dearth of relevant resources on the topic, this book will serve as a valuable resource for the candidates. The book is also aligned with preparations required for the FRCPC (Canada) and the American Board of Radiology. The book is divided into two sections - first section includes chapters on basics of breast imaging along with a chapter on emerging technologies while the second section includes 50 exam-relevant cases covering imaging findings utilizing appropriate BI-RADS lexicon, possible differentials, next recommended investigation and appropriate management in accordance with American College of Radiology lexicon, BI-RADS system and MRI correlation, whenever available. Readers also get familiar with the indications for breast MRI. The book is written by experts in breast imaging with relevant teaching experience. Written by an experts with strong teaching experience, this book is not only suitable for exams but is also useful for practicing breast and non-breast radiologists as well as breast care clinicians, keen to learn fundamentals of breast imaging.

Contents:
Intro
Preface
Acknowledgments
Contents
About the Authors
Abbreviations
Part I: Basics of Breast Imaging
1: General Considerations in Breast Imaging
1.1 Anatomy
1.2 Anatomy of Axillary Nodes (Figs. 1.2 and 1.3)
1.3 Scheduling
1.4 Patient History and Clinical Details
Suggested Readings
2: Mammography
2.1 Mammographicy Technique
2.2 Quality Assurance in Mammography
2.3 Positioning
2.4 Breast Compression
2.5 Labeling
2.6 Breast Composition
2.7 Assessing the Adequacy of Mammographic Views
2.8 Approach to Reading a Mammogram Suggested Readings
3: Additional Views
Suggested Readings
4: Breast Ultrasound
Suggested Readings
5: Breast MRI
5.1 Screening
High-Risk Screening
Foreign Body Injections
Surveillance
5.2 Diagnostic
Suggested Readings
6: Screening
6.1 Average-Risk Population Screening Guidelines
6.2 High-Risk Population Screening Guidelines
Suggested Readings
7: Digital Breast Tomosynthesis
7.1 Performance of DBT for Screening
7.2 DBT and Calcifications
7.3 DBT and Radiation Dose
7.4 DBT and Synthetic View
7.5 DBT and Time 7.6 DBT for Diagnostic Workup
7.7 DBT Biopsy and Contrast-Enhanced DBT
Suggested Readings
8: BI-RADS Lexicon
Suggested Reading
9: Organization of Breast Imaging Reports
9.1 Indication for Examination
9.2 Breast Composition Description
9.3 Clear Description of any Important Findings
Mammograms
Ultrasound
MRI
9.4 Comparison with Prior Study
9.5 Assessment Category
9.6 Management
Suggested Reading
10: Emerging Technologies
10.1 Contrast Enhanced Mammogram (Fig. 10.1)
10.2 Elastography (Fig. 10.2) Static Ultrasound Elastography: Strain Imaging
Dynamic Ultrasound Elastography: Shear Wave Imaging
Automated Breast Ultrasound (ABUS) (Fig. 10.3)
Suggested Readings
Part II: Case Based Review
11: Calcifications
11.1 Case 11.1
Questions
Answers
Notes
Breast Calcifications
Morphology
Distribution
11.2 Case 11.2
Questions
Answers
Notes
Ductal and Lobular Proliferations
Atypical Ductal Hyperplasia (ADH)
Lobular Neoplasia (LN)
Management
11.3 Case 11.3
Questions
Answers
Notes
Fibrocystic Change (FCC)
11.4 Case 11.4 Questions
Answers
Notes
Secretory Calcifications (Plasma Cell Mastitis)
11.5 Case 11.5
Questions
Answers
Notes
Ductal Carcinoma In Situ (DCIS)
Management
11.6 Case 11.6
Questions
Answers
Notes
Paget's Disease
11.7 Case 11.7
Questions
Answers
Notes
Recurrent DCIS
Radiological-Pathological (Rad-Path) Concordance
Category 1: Concordant Malignancy
Category 2: Discordant Malignancy
Category 3: Concordant Benign
Category 4: Discordant Benign
Category 5: Borderline or High Risk
Suggested Readings

Summary: This book provides a concise review of essential radiology findings for interpreting multimodality images of the breast. It includes over 90 cases that present patient history, radiologic findings, common diagnoses, and discussion points, accompanied by over 360 high-quality digital images derived from mammography, ultrasound, MRI, and PET modalities. It also presents concise pearls covering the basics of interventional breast procedures; high-yield facts vital to the practice of breast imaging; and a quick reference to the fifth edition of the American College of Radiology Breast Imaging-Reporting and Data System (BI-RADS) Atlas for mammography, ultrasound, and breast MRI. Breast Imaging Review: A Quick Guide to Essential Diagnoses, 2nd Edition, is a valuable resource for radiology residents preparing to take the core and certifying exams as well as for fellows and practicing radiologists interested in reviewing the basics of breast imaging interpretation and interventional procedures.

Contents:
Mammography and Ultrasound Review
MRI Case Review
Interventional Breast Procedures
High-Yield Facts. BI-RADS Key Facts.

Summary: Breast MRI is a comprehensive, practical resource entirely devoted to this state-of-the-art technique, which has emerged as a valuable adjunct to the conventional imaging modalities in the detection of primary and recurrent breast cancer. This brand-new medical reference book utilizes an atlas-type format that showcases numerous examples of each aspect of breast MRI, equipping you with the latest knowledge on effective breast image interpretation. Compare your breast imaging findings to a wealth of breast MRI examples that capture the characteristic clinical presentation of both normal and diseased patients. Apply the most up-to-date information available on all aspects of breast MRI, including MRI-guided biopsy, breast cancer screening with MRI, MRI features of benign and malignant lesions, and MRI in the evaluation of newly diagnosed breast cancer.Take advantage of an image-rich, atlas-type format that offers the visual clarity you need for accurate interpretation.Access the full text and images online at Expert Consult.

Contents:
Setting up and optimizing a breast MRI practice
Optimizing the breast MRI protocol
Computer-aided detection for breast MRI
Screening for breast cancer with breast MRI
MRI features of ductal carcinoma in situ
MRI features of invasive disease
Benign findings in breast MRI
MRI of high-risk breast lesions
MRI evaluation of the patient with breast cancer
MRI of the postoperative breast
MRI for breast implant evaluation
MRI-guided breast biopsy.

Summary: This book offers a comprehensive overview of the use of breast MRI for screening high-risk women, including those with familial-genetic hereditary predisposition and previous chest radiation therapy, typically lymphoma survivors. It discusses the historical background of studies and research that provided the body of evidence in favor of MRI screening of these women. Technical and clinical topics are treated in dedicated chapters, including models for individualized risk estimation, radiogenomics of breast cancer in high-risk women, computer-aided detection/diagnosis and machine learning systems applied to breast MRI, and psycho-oncology issues. Alternatives to breast MRI screening such as pharmaco-prevention and prophylactic mastectomy are also discussed, taking into account the public debate on the "Angelina Jolie" effect. The high breast cancer risk model is proposed as a paradigm for personalized medicine. This book will be of interest to radiologists, surgeons, oncologists and to all professionals devoted to female healthcare.

Contents:
Introduction
Thirty years of contrast enhanced breast MRI
The mantra about low specificity breast MRI
BRCA and other genes conferring hereditary breast cancer predisposition
Screening mammography: One size fits all?
MRI protocols for breast cancer screening
Contrast materials for screening MRI and concerns about tissue deposition
Applying MRI BI-RADS in a high-risk population
CAD systems for breast MRI screening
Phenotype presentation and radiogenomics of breast cancer with special focus on high-risk women
The body of primary evidence about MRI for high risk screening: retrospective and prospective studies
High-risk screening: MRI alone?
Secondary evidence from systematic reviews and meta-analyses
Radioprotection issues for women with hereditary predisposition for breast cancer
Impact of MRI screening on high-risk patient outcome
The special case of previous chest radiation therapy
IT infrastructure for data managing in multicenter high-risk screening
Guidelines and recommendations all over the world: agreements and differences
Medical options: Pharmacopreventio- Surgical options: Prophylactic mastectomy and oophorectomy
Psychosocial aspects of high-risk of breast cancer
Calculating, using and improving individual breast cancer risk estimates
MRI for screening women with a personal history of breast cancer
Screening MRI for the intermediate risk: an open issue
Looking at the future: Personalized breast cancer screening
Acknowledgments. .

Contents:
Overview of breast MRI / Gillian M. Newstead
Who should be screened? / Gillian M. Newstead
Screening MRI : DCE-MRI methods / Gregory S. Karczmar, Frederico D. Pinedo, and Naoko Mori
Screening MRI : clinical implementation / Gillian M. Newstead
Diagnostic MRI : imaging protocols and technical considerations / Gillian M. Newstead
Diagnostic MRI interpretation / Gillian M. Newstead and Michael Middleton
Image interpretation : non-invasive cancer / Gillian M. Newstead
Image interpretation : invasive cancer / Gillian M. Newstead
Management of findings initially detected at MRI / Hiroyuki Abe
Diagnostic MRI : breast cancer applications / Gillian M. Newstead
Advanced breast MRI techniques / Milicia Medved
Semi-quantitative and quantitative analysis of breast DCE-MRI / Gregory S. Karczmar and Frederico D. Pineda
Future applications : radiomics and deep learning on breast MRI / Maryellen L. Giger.

Summary: This atlas serves as a basic introduction to breast MRI. Organized by case, it emphasizes pertinent breast MRI findings and common indications for breast MRI. Topics include breast MRI basics, benign findings, breast malignancy, high-risk conditions, interesting cases, and breast implants. Brief teaching points accompany each case and highlight the importance of the findings. Breast MRI Teaching Atlas is an ideal resource for diagnostic radiologists, residents, fellows, and clinicians involved in the care of breast cancer patients, including surgeons, oncologists, and obstetricians/gynecologists.

Contents:
Breast MRI basics
Benign findings
Breast malignancy
High risk
Interesting cases
Breast implants.

Contents:
Section 1. Techniques
1. Breast MRI Technique
2. Breast MRI: Standing Terminologies and Reporting
Section 2. Indications
3. MRI and Screening
4. MRI and Preoperative Staging in Women Newly Diagnosed with Breast Cancer
5. Magnetic Resonance Imaging and Noeadjuvent Chemotherapy
6. Breast MRI and Implants
7. Problem Solving Breast MRI for Mammographic, Sonographic, or Clinical Findings
8. Post-Operative findings/recurrent disease
Section 3. MRI Findings, Interpretation and Management
9. In Situ Disease on Breast MRI
10. MRI appearance of Invasive Breast Cancer
11. Targeted Ultrasound after MRI
12. Breast Biopsy and Breast MRI Wire Localization
13. Breast MRI and the Benign Breast Biopsy
14. BI-RADS 3 Lesions on MRI
15. Multiparametric Imaging: Cutting-Edge Sequences and Techniques including Diffusion-Weighted Imaging, Magnetic Resonance Spectroscopy, and PET/CT or PET/MRI
16. Abbreviated Breast MRI
17. Personalized Medicine, Biomarkers of Risk and Breast MRI.

Summary: "Written with useful practicality in mind, Breast Pathology, 3rd Edition, provides surgical pathologists with authoritative guidance on the selection and best use of proper diagnostic techniques when reporting on breast specimens. Dr. David J. Dabbs and a team of internationally acclaimed pathologists incorporate genomic and molecular information, gross and microscopic findings, radiologic and laboratory diagnosis, theranostics, and immunohistochemistry to cover every aspect of benign and malignant lesions of the breast, helping you minimize diagnostic variation and error in the sign-out room"-- Provided by publisher.

Contents:
Breast Development, Physiology, and Histology
Reactive and Inflammatory Conditions of the Breast
Infections of the Breast
Epidemiology of Breast Cancer
Patient Safety in Breast Pathology
Gross Examination of Breast Specimens
Sentinel Lymph Node Biopsy
Breast Imaging Modalities for Pathologists
Predictive and Prognostic Marker Testing in Breast Pathology: Immunophenotypic Subclasses of Disease
Molecular-Based Testing in Breast Disease for Therapeutic Decisions
Diagnostic Immunohistology of the Breast
Fibroepithelial Lesions
Papilloma and Papillary Lesions
Adenosis and Microglandular Adenosis
Nipple Adenoma (Florid Papillomatosis of the Nipple)
Radial Scar
Myoepithelial Lesions of the Breast
Fibrocystic Change and Usual Epithelial Hyperplasia of Ductal Type Fibrocystic Change
Columnar Cell Change, Flat Epithelial Atypia, and Atypical Ductal Epithelial Hyperplasia
Molecular Classification of Breast Carcinoma
Lobular Neoplasia and Invasive Lobular Carcinoma
Ductal Carcinoma In Situ
Invasive Ductal Carcinoma of No Special Type and Histological Grade
Triple-Negative and Basal-like Carcinoma
Metaplastic Breast Carcinoma
Apocrine Carcinoma of the Breast
Paget's Disease of the Breast
Pathology of Neoadjuvant Therapeutic Response of Breast Carcinoma
Special Types of Invasive Breast Carcinoma: Tubular Carcinoma, Cribriform Carcinoma, Mucinous Carcinoma, Micropapillary Carcinoma
Rare Breast Carcinomas: Adenoid Cystic Carcinoma, Neuroendocrine Carcinoma, Secretory Carcinoma, Carcinoma With Osteoclast-like Giant Cells, Lipid-Rich Carcinoma, and Glycogen-Rich Clear Cell Carcinoma
Mesenchymal Tumors of the Breast
Neoplasia of the Male Breast
Breast Tumors in Children and Adolescents
Hematolymphoid Tumors of the Breast
Metastatic Tumors in the Breast
Next-Generation Sequencing and the Management of Patients With Clinically Advanced Breast Cancer.

Contents:
1. Normal breast and developmental disorders
2. Reactive and inflammatory conditions of the breast
3. Infections of the breast
4. Epidemiology of breast cancer and pathology of heritable breast cancer
5. Patient safety in breast pathology
6. Gross examination of breast pathology
7. Sentinel lymph node biopsy
8. Breast imaging modalities for pathologists
9. Predictive and prognostic marker testing in breast pathology: immunophenotypic subclasses of disease
10. Molecular-based testing in breast disease for therapeutic decisions
11. Diagnostic immunohistology of the breast
12. Fibroepithelial lesions
13. Papilloma and papillary lesions
14. Adenosis and microglandular adenosis
15. Nipple adenoma (florid papillomatosis of the nipple)
16. Radial scar
17. Myoepithelial lesions of the breast
18. Fibrocystic change and usual epithelial hyperplasia of ductal type
19. Columnar cell alterations, flat epithelial atypia, and atypical ductal epithelial hyperplasia
20. Molecular classification of breast carcinoma
21. Lobular neoplasia and invasive lobular carcinoma
22. Ductal carcinoma in situ
23. Invasive ductal carcinoma of no special type and histologic grade
24. Triple-negative and basal-like carcinoma
25. Metaplastic breast carcinoma
26. Apocrine carcinoma of the breast
27. Paget disease of the breast
28. Pathology of neoadjuvant therapeutic response of breast carcinoma
29. Special types of invasive breast: tubular carcinoma, mucinous carcinoma, cribriform carcinoma, micropapillary carcinoma, carcinoma with medullary features
30. Rare breast carcinomas: adenoid cystic carcinoma, neuroendocrine carcinoma, secretory carcinoma, carcinoma with osteoclast-like giant cells, lipid-rich carcinoma, and glycogen-rich clear cell carcinoma
31. Mesenchymal neoplasms of the breast
32. Neoplasia of the male breast
33. Breast tumors in children and adolescents
34. Tumors of the mammary skin
35. Hematopoietic tumors of the breast
36. Metastatic tumors in the breast
37. Next-generation DNA sequencing and the management of patients with clinically advanced breast cancer.

Summary: This book covers the complete field of breast pathology - from Acinic cell carcinoma to Usual Epithelial Hyperplasia. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.

Contents:
Abscess
Acinic cell carcinoma
Adenoid cystic carcinoma
Adenomyoepithelioma
Adenomyoepithelioma with carcinom
Adenosis
Angiomatosis
Angiosarcoma of the breast
Apocrine adenoma
Apocrine adenosis
Apocrine Carcinoma
Atypical Ductal Hyperplasia
Atypical vascular proliferations
Benign peripheral nerve sheath tumor
Breast implant associated malignant lymphoma
Collageous spherulosis
Atypical Ductal Hyperplasia
Columnar cell lesions
Complex Sclerosing Lesion
Congenital abnormalities
Diabetic Fibrous Mastopathy
Duct ectasia and periductal mastitis
Ductal adenoma
Ductal carcinoma in situ
Encapsulated papillary carcinoma
Fat necrosis
Fibrocystic Changes
Fibroadenoma
Glycogen rich clear cell carcinoma
Granulomatous mastitits
Gynecomastia
Hamatoma
Hemangioma
Hormone receptors in breast cancer
Granular Cell Tumor
HER2 in breast cancer
Infarct
Inflammatory myofibroblastic tumor
Intraductal papilloma
Intraductal papillary carcinoma
Invasive adenosquamous carcinoma
Invasive Cririform Carcinoma
Invasive Carcinoma NST
Invasive Carcinoma with medullary features
Invasive lipid-rich carcinoma
Invasive Carcinoma with neuroendocrine features
Invasive Lobular Carcinoma
Invasive Metaplastic carcinoma
Invasive Micropapillary carcinoma
Invasive Mucinous carcinoma
Invasive oncocytic carcinoma
Invasive papillary carcinoma
Invasive Tubular Carcinoma
Invasive sebaceous carcinoma
Invasive Secretory carcinoma
Invasive carcinoma with signet ring cell differentiation
Juvenile papillomatosis
Lipoma
Liposarcoma
Lobular in situ neoplasia
Male breast cancer
Microglandular adenosis
Microinvasive carcinoma
Mucoepidemoid carcinoma
Mucocele-like lesion
Myoepithelial carcinoma
Myoepithelial hyperplasia
Myofibroblastoma
Paget disease of the nipple
Pleomorphic adenoma
Pleomorphic lobular carcinoma
Phyllodes tumor
Polymorphous Carcinoma
Pseudoangiomatous Stromal Hyperplasia
Radial Scar
Sentinel node
Sclerosing Adenosis
Syringomatous adenoma of the nipple
Tall cell variant of papillary breast carcinoma
Tubular adenoma
Usual Epithelial Hyperplasia.

Summary: This book covers practical diagnostic issues in breast pathology, with special emphasis on areas which pose diagnostic difficulties. These include dealing with the gross specimens derived from patients treated with conservative surgery and those who had neo-adjuvant therapy before surgery. It also discusses how to deal with axillary lymph nodes, proliferative breast lesions, including DCIS, and problematic core biopsies, as well as fibro-epithelial, spindle cell, lobular, mucinous, metaplastic and papillary lesions, molecular classification of breast cancers, breast lesions in male patients and breast immunohistochemistry. There is a focus on unusual benign and malignant breast lesions and a large number of high-quality images help the reader diagnose difficult cases. Breast Pathology: Problematic Issues is aimed at histopathology consultants and senior trainees who deal with breast pathology.

Contents:
Dealing with the gross specimen
Handling Neo-Adjuvant therapy Specimens
Proliferative Breast Lesions
Problematic Core Biopsies
Ductal Carcinoma in Situ
Lobular neoplasia
Grading of invasive carcinoma
Fibroepithelial Lesions
Mucinous Lesions of the breast and expression of WT1
Spindle cell lesions
Papillary carcinomas
Metaplastic breast carcinomas
Metastatic lesions in the breast
Axillary Lymph node biopsies
A Practical Approach to the use of Immunohistochemistry in the Diagnosis and Management of Breast Disease
Molecular classification and testing of breast carcinoma
Uncommon benign breast lesions
Uncommon malignant lesions
Male breast lesions.

Summary: This book provides a concise, step-by-step guide to accurate microscopic diagnosis for clinicians who deal with patients with breast lesions. The emphasis is on a practical approach to dealing with breast biopsies and reaching a diagnosis. It outlines the procedures used for the microscopic diagnosis of various breast lesions and the significance of the nomenclature and terms used in pathology reports, including those dealing with uncommon or rare lesions. Ample illustrations of the lesions discussed are included, particularly those dealing with uncommon and border-line lesions. There is a special emphasis on breast cancer and on the fact that not all breast cancers are the same. The different ways by which breast cancers are classified are discussed including recent classifications which lead to personalized therapy. The book is aimed at pathologists of all grades who deal with breast biopsies including those in training. It would be also useful for practicing and trainee surgeons and oncologists as well as other health professionals dealing with patients with breast diseases and scientists carrying out research on breast problems.

Contents:
Intro
Contents
1: Introduction
References
2: Core Biopsy
The Patient
The Lesion
The Doctor
The Needle
Type of Biopsies
The Sample
The Request Form
The Laboratory
The Pathologist
The Multi-disciplinary Team Meeting (MDT)
References
3: Reporting Core Biopsies: Benign (B2) Lesions
Introduction: Is the Lesion Benign or Malignant?
Benign Lesions That Do Not Usually Need Further Intervention (B2 Lesions)
Fibroadenoma
Special Types of Fibroadenomas
Hamartoma
Fibrocystic Change
Ductal Hyperplasia Differentiating Regular Hyperplasia (B2) from Atypical Hyperplasia (B3) and Low Grade DCIS (B5a)
Columnar Cell Change and Columnar Cell Hyperplasia
Sclerosing Adenosis and Apocrine Adenosis
Duct Ectasia
Granulomatous Mastitis
Other Inflammatory Conditions
Other Less Common Benign Conditions
References
4: Reporting Core Biopsies: Benign Lesions That Usually Need Further Intervention (B3 Lesions)
Introduction
Atypical Epithelial Hyperplasia (ADH)
Flat Epithelial Atypia (FEA)
In Situ Lobular Neoplasia
Radial Scar/Complex Sclerosing Lesions Intraduct Papillomas
Cellular Fibro-Epithelial Lesions
Spindle Cell Lesions
Mucocele Like Lesions
Microglandular Adenosis
Benign and Atypical Vascular Lesions
Granular Cell Tumour
Collagenous Spherulosis
Epithelial Myoepithelial Benign Lesions
General Remark: Risk of Malignancy in Benign Breast Lesions Discovered During Mammography
References
5: Reporting Core Biopsies: Lesions That Are Highly Suspicious of Malignancy (B4) or Definitely Malignant (B5)
B4 Lesions
B5 Lesions
B5a (Non-invasive Lesions)
In Situ Carcinoma
Ductal Carcinoma In Situ (DCIS) Incidence of Metastasis and Death After Diagnosing DCIS
Lobular Carcinoma In Situ (LCIS)
Paget's Disease of the Nipple
Intracystic and Solid Papillary Carcinomas
Invasive Lesions (B5b)
Primary Invasive Breast Carcinoma
Morphological Types
Invasive Ductal Carcinoma
Pleomorphic Invasive Ductal Carcinoma
Invasive Lobular Carcinoma
Invasive Tubular Carcinoma
Invasive Cribriform Carcinoma
Invasive Mucinous Carcinoma
Lympho-Epithelioma-Like Carcinoma
Invasive Apocrine Carcinoma
Invasive Papillary Carcinoma
Invasive Micropapillary Carcinoma Neuroendocrine Tumours of the Breast
Glycogen-Rich Clear Cell Carcinoma
Lipid-Rich Carcinoma
Triple Negative Invasive Breast Carcinoma
Grading of Primary Invasive Breast Carcinoma
Other Additional Features That Should Be Mentioned in the Core Biopsy Report
ER and PR Assessment
HER2 Assessment [75]
Other Immunohistological Studies
Molecular Classification of Breast Carcinoma
Complete Removal of Lesions
Primary Sarcomas of the Breast
Angiosarcoma
Mammary Sarcoma with CD10 Expression (Fig. 5.60)
Stromal Sarcoma
Primary Osteogenic Sarcoma

Summary: This book examines distinct innovative and modern techniques for breast reconstruction after a mastectomy necessitated by breast cancer. It serves as not only an entry point in learning about the most modern and promising surgical techniques available, but as a pragmatic guide as well. Beginning with an introduction to the history of the subject, the opening chapter offers a lesson in the evolution of the development and improvement of breast reconstruction techniques. Following this, chapters examine anatomic landmarks, including vascular anatomy, design and markings and best indications depending on the type of breast to be reconstructed. Subsequent chapters then present a multitude of surgery methods, including the progression from large open surgical procedures, to endoscopic approaches, and robotic assisted minimally invasive surgery. Finally, scaffold-based tissue engineering that offers a promising future for breast reconstruction surgeries without donor site morbidity is also reviewed. Additionally, the book's expertly written text is supplemented by high-quality illustrations and videos that provide vital surgical guidance for improved surgical outcomes. Comprised of contributions from world-renowned plastic surgeons, Breast Reconstruction: Modern and Promising Surgical Techniques is an invaluable reference for residents, fellows, practicing and highly experienced plastic surgeons, breast surgeons, and those in surgical sub-specialties.

Contents:
1. History of Breast Reconstruction
2. Partial breast reconstruction
3. Breast reconstruction with the permanent tissue expander
4. Synthetic meshes in breast reconstruction
5. Biologic meshes in breast reconstruction
6. Prepectoral breast reconstruction
7. Breast reconstruction with fat grafting alone
8. Hybrid Breast Reconstruction
9. Breast Reconstruction with intratissular expansion and fat grafting
10. Breast Reconstruction with external expansion and fat grafting
11. Breast Reconstruction with the latissimus dorsi flap and fat grafting
12. Breast Reconstruction with the endoscopically harvested latissimus dorsi flap
13. Breast Reconstruction with the robotic-assisted latissimus dorsi harvest
14. Total breast reconstruction using the thoracodorsal artery perforator flap TDAP
15. Breast reconstruction using the muscle sparing lattisimus dorsi flap with alloplastic devices
16. Free and Muscle Sparing TRAM flap in breast reconstruction
17. DIEP flap in breast reconstruction
18. Breast Reconstruction with the neurotized Deep Inferior Epigastric Perforator Flap
19. Breast Reconstruction with Simultaneous Lymphatic Transfers
20. SIEA flap in breast reconstruction
21. Breast Reconstruction with the laparoscopically harvested Omental Free Flap
22. Lumbar artery perforator flap for breast reconstruction
23. Superior Gluteal Artery Perforator flap in breast reconstruction
24. Inferior Gluteal Artery Perforator flap in breast reconstruction
25. Lateral thigh flap in breast reconstruction
26. Transverse upper gracilis flap in breast reconstruction
27. Profunda artery perforator flaps for breast reconstruction
28. Breast reconstruction with perforator flap transplants from identical twins
29. Breast reconstruction using scaffold-based tissue engineering.

Summary: This book describes the various techniques available for autologous breast reconstruction, be it breast conserving therapy (BCT) or reconstruction following total mastectomy with local and distant flaps. Divided into two parts, the first presents the anatomy of the breast and the general requirements with regard to this kind of surgery. In turn, the second addresses reconstructive breast surgery management. The authors present oncoplastic procedures for reconstructing the breast following small defects due to cancer or other conditions (BCT), as well as the use of microvascular free flaps, such as abdominal, thigh or gluteal-based flaps, for a complete reconstruction. Preventive reconstructive surgery and cutting-edge techniques, such as lipofilling or breast reconstruction together with lymph node transplantation, are also included. Written by leading international plastic surgeons and combining step-by-step explanations and detailed illustrations, this book clearly demonstrates that reconstructive procedures can have aesthetic outcomes.

Contents:
Introduction: Breast Anatomy
General. Reconstructive Surgery: General Remarks on Breast Cancer
Tumor Excision
Breast Conserving Therapy (BCT)
Oncoloplastc Surgery
Mastectomy
Autologous Reconstruction
Lipofilling
Reconstruction of nipple and Areola
Index.

Summary: "Breast cancer represents the most common cancer that affects women of the industrial and impoverished nations of the world; this neoplasm has a lifetime risk to affect one in every eight women of the industrialized countries with various presentations and stages of disease. Surgical therapy remains one of the principal modalities utilized to treat this organ -centric cancer. Surgical treatment of breast cancer has evolved over the past century from radical debilitating surgeries to minimally- invasive approaches that have advanced with earlier diagnosis and highly- effective neoadjuvant therapies. These more plausible and highly acceptable minimally -invasive techniques have progressed from disfiguring procedures to reconstruction excellence. Moreover, the entire field of breast cancer surgery is advancing very rapidly globally, thus, many of the procedures illustrated in this text are not readily applied in community surgical practice and certainly not in such an eclectic textural format"--Provided by publisher.

Contents:
Machine generated contents note: pt. I Breast and Axillary Imaging
ch. 1 Topographical Surgical Anatomy of the Breast, Axilla, Chest Wall, and Metastatic Sites / Kirby I. Bland
ch. 2 Breast and Axillary Imaging for the Surgeon / Edgar D. Staren
pt. II Breast Biopsy
ch. 3 Drainage of Breast Cysts and Abscesses / Amy C. Degnim
ch. 4 Ultrasound-Cuided Breast Percutaneous Needle Biopsy / V. Suzanne Klimberg
ch. 5 Stereotactically Guided Breast Percutaneous Needle Biopsy / Arthur G. Lerner
ch. 6 Breast Ductoscopy / William C. Dooley
ch. 7 Excisional Breast Biopsy of Palpable Lesions / Edward M. Copeland
ch. 8 Needle Localization Biopsy of Nonpalpable Breast Lesions / Virginia M. Herrmann
ch. 9 Intraoperative Ultrasound-Guided Excision of Nonpalpable Lesions / Amy E. Rivere
ch. 10 Breast Surgery After Radioactive Seed Localization / Barbara A. Pockaj Note continued: ch. 11 Fluoroscopic Intraoperative Node or Neoplasia Detection (FIND) Procedure / V. Suzanne Klimberg
pt. III Lymph Node Mapping, Dissection and Reconstruction
ch. 12 Axillary Sentinel Lymph Node Biopsy / Julie A. Margenthaler
ch. 13 Internal Mammary Sentinel Lymph Node Biopsy / Virgilio Sacchini
ch. 14 Axillary Lymph Node Dissection / Kirby I. Bland
ch. 15 Axillary Reverse Mapping / H. Colleen Silva
ch. 16 Surgical Techniques for Prevention and Treatment of Breast Cancer Related Lymphedema; Multiple Lymphatic Venous Anastomoses (MLVAs)
Including LYMPHA / Sheldon Marc Feldman
ch. 17 Lymphatic Reconstruction With Vascularized Lymph Node Transfer / Cristiano Boneti
pt. IV Partial Mastectomy
ch. 18 Partial Mastectomy / Sarah P. Cate
ch. 19 Excision Followed by Radiofrequency Ablation / Amy E. Rivere
ch. 20 Breast Brachytherapy Device Placement / Peter D. Beitsch
ch. 21 Intraoperative Radiotherapy / Stephen R. Grobmyer Note continued: pt. V Mastectomy
ch. 22 Simple Mastectomy / Kirby I. Bland
ch. 23 Modified Radical Mastectomy and Total (Simple) Mastectomy / Kirby I. Bland
ch. 24 Radical Mastectomy / Kirby I. Bland
pt. VI Oncoplastic Breast Surgery
ch. 25 Oncoplastic Breast Conservation Techniques in Upper Pole Lesions / Russell J. Bramhall
ch. 26 Oncoplastic Breast Conservation Techniques in Lower-Pole Lesions / Abby K. Geletzke
ch. 27 Oncoplastic Breast Conservation Techniques in Subareolar Lesions / Nicolas Ajkay
ch. 28 Reduction Mammaplasty/Mastopexy and Therapeutic Mammaplasty (Oncoplastic Mammaplasty): Principles and Mark Up / Shadi Ghali
ch. 29 Oncoplastic Breast Reconstruction: Extreme Oncoplasty and Split Reduction Techniques / Melvin J. Silverstein
ch. 30 Total Skin-Sparing Mastectomy/Nipple Skin-Sparing Mastectomy / Linda Philips
ch. 31 Skin-Sparing Mastectomy for the Pendulous Breast / Jill R. Dietz Note continued: ch. 32 The Goldilocks Mastectomy / Grace Y. Ma
ch. 33 Alternatives to Tissue Rearrangement: Suture Lattice Technique Combined With Absorbable Radiographic 3D Tissue Marker for Cavity Marking and Cosmesis / Anthony Lucci
pt. VII Extensive Resections
ch. 34 Chest Wall Resection and Reconstruction for Advanced/Recurrent Carcinoma of the Breast / Robert J. Cerfolio
ch. 35 Skin Flaps for Extensive Soft Tissue and Skin Resection / Luis O. Vasconez
ch. 36 Forequarter Amputation / Keila E. Torres
pt. VIII Breast Reconstruction
ch. 37 Implant-Based Reconstruction / James C. Yuen
ch. 38 Autologous Fat Grafting for Correction of Residual Contour Deformities After Breast Reconstruction / Lee L.Q. Pu
ch. 39 Autologous Reconstruction: TRAM Flap / Luis O. Vasconez
ch. 40 Autologous Reconstruction: Microvascular MS-TRAM and DIEP Flaps / David W. Chang
ch. 41 Autologous Reconstruction: Latissimus Dorsi Flap / Steven J. Kronowitz Note continued: ch. 42 Autologous Reconstruction: Gluteal Flap Breast Reconstruction / Michael R. Zenn
ch. 43 Secondary Reconstruction: Reduction Mammoplasty, Mastopexy, and Breast Augmentation / Nolan S. Karp
ch. 44 Secondary Reconstruction: Nipple-Areolar Reconstruction / Victor Chien.

Summary: Breast Surgery meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of this sub-specialty that is relevant to their general surgical practice. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance.

Contents:
The role of imaging in breast diagnosis including screening and excision of impalpable lesions / A. Robin M. Wilson and R. Douglas Macmillan
Pathology and biology of breast cancer / Rajendra S. Rampaul [and others]
Nipple discharge and the role of ductoscopy in breast diseases / Sarah Tang and Gerald Gui
Breast-conserving surgery : the balance between good cosmesis and local control / J. Michael Dixon
Techniques of mastectomy : tips and pitfalls / R. Douglas Macmillan
Oncoplastic procedures to allow breast conservation and a satisfactory cosmetic outcome / Richard M. Rainsbury [and others]
The axilla : current management including sentinel node and lymphedema / Anees B. Chagpar
The genetics of breast cancer, risk-reducing surgery, and prevention / D. Gareth, R. Evans and Ava Kwong
Breast reconstruction / Mark Schaverien and Cameron Raine
Breast cancer treatments of uncommon diseases / Daniel Xavier Choi and Monica Morrow
Treatment of ductal carcinoma in situ / Nicola L.P. Barnes and Nigel J. Bundred
The role of adjuvant systemic therapy in patients with operable breast cancer / Rosalie Fisher and Ian Smith
Locally advanced breast cancer / Douglas J.A. Adamson and Alastair M. Thompson
Metastatic disease and palliative care / John Dewar and Pamela Levack
The role of adjuvant radiotherapy in the management of breast cancer / Ian Kunkler
Psychosocial issues in breast cancer / Lesley Fallowfield and Valerie Jenkins
Benign breast disease / Steven Thrush and J. Michael Dixon
Litigation in breast surgery / Tim Davidson and Tom Bates.

Summary: "Breast Surgery provides a short, up-to-date and practical reference guide for general surgical trainees and established consultants needing a refresher. The seventh edition has been edited and fully revised by respected experts in their fields, and provides a full list of current references and relevant resources. It includes recent developments in breast surgery, including axillary surgery, primary medical therapy, risk reducing surgery, gender affirmation surgery and complications of breast surgery."--Provided by publisher.

Contents:
Anatomy and physiology of the breast
Assessment of patient, breast and common clinical presentations including image-guided intervention
Benign breast conditions
Breast pathology
Epidemiology, risk factors and prevention strategies
Breast screening
Breast-conserving surgery : the balance between good cosmesis and local control
Oncoplastic breast-conserving surgery
Mastectomy
Management of the axilla
Uncommon presentations of cancer affecting the breast and recurrent breast cancer
Breast reconstruction
Treatment of ductal carcinoma in situ
The role of adjuvant systemic therapy in patients with operable breast cancer
Neoadjuvant therapy for breast cancer, including surgical considerations
Adjuvant radiotherapy for breast cancer
Metastatic breast cancer and palliative care
Top surgery for gender affirmation
Psychosocial issues in breast cancer
Avoidance and management of complications of breast surgery.

Contents:
Physics and development of breast tomosynthesis / Loren Niklason
The technologist's perspective / Regina J. Hooley, Amanda Albarella, Liane E. Philpotts
Implementation of digital breast tomosynthesis into clinical practice / Stamatia Destounis, Andrea Arieno, Renee Morgan, Liane E. Philpotts
Tomosynthesis in screening mammography / Melissa Durand, Liane E. Philpotts
Tomosynthesis in diagnostic mammography / Reni Butler, Regina J. Hooley
Tomosynthesis interpretation tips and pitfalls / Liane E. Philpotts, Regina J. Hooley
Benign findings / Laura Sheiman, Liane E. Philpotts
Malignant findings / Paul H. Levesque, Regina J. Hooley
Architectural distortion / Madhavi Raghu, Regina J. Hooley
Integrating tomosynthesis with multimodality imaging / Liva Andrejeva, Jaime Geisel, Liane E. Philpotts
The postoperative breast / Laura J. Horvath, Liane E. Philpotts
Tomosynthesis in the male breast / Liane E. Philpotts
Interventional procedures / Margarita Zuley, Ernestine Thomas, Jules H. Sumkin.

Contents:
Breastfeeding, ninth edition
previous version available until may previous version
-- Breastfeeding in a new era
Anatomy of the breast
Physiology of lactation
Biochemistry of human milk
Host-resistance factors and immunologic significance of human milk
Population health and informed feeding decisions
Practical management of the nursing “dyad”
Maternal nutrition and supplements for mother and infant
Weaning
Normal growth, growth faltering, and obesity in breastfed infants
Medications, herbal preparations, and natural products in breast milk
Transmission of infectious diseases through breast milk and breastfeeding
Breastfeeding infants with problems
Premature infants and breastfeeding
Medical complications of mothers
Breast conditions in the breastfeeding mother
Human milk and atopic disease
Breastfeeding and return to work or school
Induced lactation and relactation (including nursing an adopted baby) and cross-nursing
Chestfeeding and lactation care for LGBTQ+ families (lesbian, gay, bisexual, transgender, queer, plus)
Reproductive function during lactation
The collection and storage of human milk and human milk banking
Infant feeding after a disaster
Establishing a breastfeeding medicine practice or academic department
Breastfeeding support groups and community resources
Educating and training medical professionals
Appendices.

Summary: "Breastfeeding and Human Lactation, Sixth Edition is the ultimate reference for the latest clinical techniques and research findings that direct evidence-based clinical practice for lactation consultants and specialists. Topics include placing breastfeeding in its historical context, workplace-related issues, anatomical and biological imperatives of lactation, the prenatal and perinatal periods and concerns during the postpartum period, the mother's health, and sociocultural issues.Completely updated and revised, the new edition includes new case studies, expanded cultural content, new regulations and guidelines, more information on alternative medicine, and gender inclusive language"--Provided by publisher.

Contents:
Introduction
Infant states and infant assessment
Infant orofacial assessment and feeding reflexes
Infant stools, urine, and vaginal discharge
Appearances of human milk
Positioning and latch
Flat and inverted nipples
Sore nipples
Unusual presentations of the breast and nipple
Anatomic variability
Engorgement, oversupply, and mastitis
Breast cancer: issues for lactation
Twins, triplets, and tandem nursing
Alternative feeding methods
Breastfeeding in emergencies
Breastfeeding in special circumstances
Ankyloglossia (tongue-tie)
Cleft lip and cleft palate.

Contents:
The scope of breastfeeding
Rationale for breastfeeding : benefits to infants, mothers, and society
Composition of human milk
Anatomy and physiology of lactation
Breastfeeding : management before and after conception
Peripartum care : the transition to lactation
Breastfeeding in the hospital : the postpartum period
Maintenance of breastfeeding-the infant
Maintenance of breastfeeding-the mother
Supporting breastfeeding during mother-infant separation
Lactation support technology
Medications and breastfeeding
Contraception and the breastfeeding mother
Breastfeeding and human milk for preterm infants
Breastfeeding in special circumstances
Who can and who cannot breastfeed?
The breastfeeding-friendly medical office
Breastfeeding issues during disasters
Appendix A. Breastfeeding resources
Appendix B. American Academy of Pediatrics policy statement : breastfeeding and the use of human milk
Appendix C. American Academy of Pediatrics : the transfer of drugs and therapeutics into human breast milk
Appendix D. ACOG committee opinion #361 : breastfeeding : material
Appendix E. ACOG clinical review : breastfeeding : material and infant aspects
Appendix F. ACOG committee opinion # 570 : breastfeeding in underserved women : increasing initiation and continuation of breastfeeding.

Summary: The definitive resource for physicians and other health care professionals to be able to counsel expectant and nursing mothers and other caregivers on the most up-do-date developments in breastfeeding practice, research, policies, and outreach. Contains a wealth of information on supporting breastfeeding mothers and infants and meeting their unique physical and emotional needs.

Contents:
Front Matter
1. Evidence for Breastfeeding: Importance for Newborns and Infants, Mothers, and Society
2. The Scope of Breastfeeding
3. Composition of Human Milk
4. Nonnutritive Components in Human Milk
5. Anatomy and Physiology of Lactation
6. Breastfeeding: Management Before and After Conception
7. Breastfeeding Initiation
8. Breastfeeding in the Hospital
9. Maintenance of Breastfeeding: The Newborn and Infant
10. Maintenance of Breastfeeding: The Mother
11. The Breastfeeding-Friendly Medical Office 12. Breastfeeding and Human Milk for Preterm Newborns and Infants
13. Breastfeeding in Special Circumstances
14. Lactation Support Technology
15. Supporting Breastfeeding During Mother-Infant Separation
16. Medications and Breastfeeding
17. Contraception and the Breastfeeding Mother
18. Contraception and the Breastfeeding Mother
19. Breastfeeding Issues During Disasters
Appendix A
Appendix B
Appendix C
Appendix D
Appendix E
Appendix F
Appendix G
Appendix H
Index

Contents:
Influence of the biospecificity of human milk
Influence of the maternal anatomy and physiology on lactation
Influence of the infant's anatomy and physiology
Influence of peripartum factors, birthing practices, and early caretaking behaviors
First 24-48 hours : common challenges
Beyond the initial 48-72 hours : infant challenges
Physical, medical, and environmental problems and issues
Maternal pathology : breast and nipple issues
Physical, medical, emotional, and environmental challenges to the breastfeeding mother.

Summary: "Created by a leading breastfeeding and phone care practitioner, this newly revised problem-solver helps nurses, lactation professionals, and other medical staff confidently advise breastfeeding mothers"--Publisher's description.

Summary: Created by a leading breastfeeding and phone care practitioner, this newly revised 4th edition is a problem-solver that helps nurses, lactation professionals, and other medical staff confidently advise breastfeeding mothers. It is ideal for use with the acclaimed Pediatric Telephone Protocols. -- Provided by publisher.

Summary: One-fifth of adults suffer from bad breath, and it can be a tell-tale disease indicator. Yet most health professionals remain ill-informed about the condition. This illustrated text combines basic research with clinical approaches to diagnosis and treatment.

Contents:
Intro
Contents
1: Introduction
2: Breath Odors of Oral Origin (Oral Malodor)
2.1 Oral Malodor and the Tongue
2.2 Oral Malodor, Gingival Health, and Periodontal Disease
2.3 Oral Malodor and Dental Restorations
2.4 Oral Malodor and Oral Dryness
References
3: Biochemical and Microbial Aspects of Oral Malodor Production
3.1 The General Role of Bacteria in Breath Odors
3.2 The Bacterial Origin of Oral Odors
3.3 Metabolic Factors Affecting Malodor Production
3.4 Biochemical Aspects
3.4.1 Metabolism 3.4.2 Malodorous Volatile Organic Compounds (VOCs) in the Oral Cavity
3.5 Microbial Aspects
3.5.1 Malodor-Producing Microorganisms
References
4: Odor Perception
4.1 Olfactory Psychophysics
4.2 Odor Mixtures
4.3 Odor Perception and Odor Evaluation Panels
References
5: Breath Odors of Nasal and Pharyngeal Origin
5.1 Chronic Sinusitis
5.2 Chronic Caseous Tonsillitis
5.3 Foreign Bodies
5.4 Craniofacial Anomalies
References
6: Breath Odors and the Gastrointestinal Tract
6.1 Gastroesophageal Reflux Disease (GERD) 9.1 Pre-appointment Instructions
9.2 Patient Interview
9.3 Examination
9.3.1 Organoleptic Measurements
9.3.2 Oral VSC Quantification
9.3.3 Examination of the Oral Cavity
9.3.4 Biochemical and Microbial Assays
References
10: Self-Assessment of Breath Odors
References
11: Breath Odors, Prevalence, Gender, and Age
11.1 Prevalence
11.2 Gender
11.3 Age
References
12: Psychological Aspects of Breath Odors
12.1 Halitophobia
12.2 Olfactory Reference Syndrome (ORS)
12.3 Back to Halitophobia
References
13: Oral Malodor Management 13.1 Mechanical Therapy
13.2 Chemical Therapy
13.3 Professional Treatment
References
14: History of Breath Odors
14.1 Culture and Folklore
14.2 Early Scientific and Medical Literature
14.3 Modern History
References
15: Future Prospects
References

Summary: This book offers up-to-date information on the recording and analysis of respiratory sounds that will assist in clinical routine. The opening sections deliver basic knowledge on aspects such as the physics of sound and sound transmission in the body, a clear understanding of which is key to good clinical practice. Current techniques of breath sound analysis are described, and the diagnostic impact of advances in the processing of lung sound signals is carefully explained. With the aid of audio files that are available online, detailed guidance is then provided on differentiation of normal and abnormal breath sounds and identification of the various sounds, including crackles, wheezes, other lung sounds, cough sounds, and sounds of extrathoracic origin. The book is of high educational value and represents an excellent learning tool at pre- and postgraduate levels. It will also appeal to researchers as it provides comprehensive summaries of knowledge in particular research fields. The editors bring high-level expertise to the subject, including membership of the European Respiratory Society Task Force on the standardization of categories and nomenclature for breath sounds.

Summary: This book systematically focuses on central sleep apneas, analyzing their relationship especially with heart failure and discussing recent research results and emerging treatment strategies based on feedback modulation. The opening chapters present historical background information on Cheyne-Stokes respiration (CSR), clarify terminology, and explain the mechanics and chemistry of respiration. Following a description of the physiology of respiration, the pathophysiology underlying central apneas in different disorders and particularly in heart failure is discussed. The similarities and differences of obstructive and central apneas are then considered. The book looks beyond the concept of sleep apnea to daytime CSR and periodic breathing during effort and contrasts the opposing views of CSR as a compensatory phenomenon or as detrimental to the failing heart. The diagnostic tools currently in use for the detection of CSR are thoroughly reviewed, with guidance on interpretation of findings. The book concludes by describing the various forms of treatment that are available for CSR and by explaining how to select patients for treatment.

Contents:
1. Historical background and glossary of the apnea phenomenon.-- 2. Mechanics and chemistry of respiration in health
3. Hypopneas and apneas as physiological and pathological phenomena throughout life
4. Pathophysiology of central apneas in heart failure
5. The importance of visceral feedbacks: focus on chemoreceptors
6. The apneas before and after heart failure
7. Not only sleep apnea: the "awake" apneas of the failing heart
8. Periodic breathing during effort and central apneas in heart failure: siblings, cousins or what else?
9. To breath or not to breath- that is the question
10. Diagnostic tools: the easier, the better
11. Diagnostic tools: messages from implanted devices
12. Targeting and treating apneas
13. Final remarks.

Summary: More than 20 million childhood deaths occur every year due to the micronutrient deficiency and diet-related non-communicable diseases (cardiovascular diseases, cancers, chronic respiratory diseases and diabetes). The United Nations (UN) recently announced that the increase in chronic, non-communicable diseases has resulted in 36 million deaths around the world annually, claiming more lives than all other causes combined. These chronic diseases are not isolated to developed countries and are even more pronounced in the developing world. Such chronic illnesses have caused far more deaths than infectious diseases throughout the world (except Africa) in recent years. Therefore, enrichment of micronutrients in staple food crops is of paramount importance for the nutritional security in our world. Biofortification is the development of micronutrient- and/or vitamin-rich crops using traditional crop improvement practices as well as modern biotechnology tools. It is a more sustainable and cost effective method than food supplementation, fortification and diet diversification. This work consolidates available information on the different aspects of breeding for improved nutrition of pulses. An overview of entire pulses based on their nutritional profile is given so that audience can find the desired information easily. Food legumes are the active ingredients in many gluten-free food products and there is a continuous rise of the use of pulses flour in milling and baking processes. Our book sheds light on recent efforts and the underlying constraints of meeting the public demand. We believe this work provides the basic information for anyone interested in biofortification and stimulate further research to meet this unique challenge.

Contents:
Breeding for enhanced nutritional status: Retrospect and Prospect
Quality improvement in chickpea
Breeding for quality improvement in pigeon pea
Bio-fortification in lentil
Breeding for low phytates and oligosaccharides in mung bean and black gram
Common bean quality improvement
Breeding for reduced trypsin inhibitor in peas
Breeding for low ODAP content in Lathyrus
Breeding for high protein content in cowpea
Role of animal models in nutrition resource in food legumes
Pulses for improved milling and baking
Bio-actives and nutraceuticals in lentil.

Summary: The genomic revolution has opened many opportunities to explore relationships between genetic and phenotypic diversity of plants as never before. The joint meeting addresses challenges of combining genetic resources and advanced omics technologies for enhancing development of next generation breeding strategies that will move plant breeding a step forward. Selection based on genomic technologies allows simultaneous marker discovery and validation, however high- throughput and precise phenotyping remains a major bottleneck limiting the power and resolution of genetic analysis. Additionally, novel sequencing technologies and automated phenotyping approaches generate big data sets requiring efficient data analysis and decision support tools that help breeders to select the superior material for their breeding programs.

Contents:
Intro; Preface; Contents; Utilization of Genetic Resources and Pre-breeding; Utilization of Genebank Accessions to Improve Northern Adaptation of Perennial Ryegrass (Lolium perenne L.); Abstract; 1 Introduction; 2 Materials and Methods; 2.1 Plant Material, Phenotyping and Pre-breeding; 2.2 Genotyping, Ploidy Testing; 3 Results and Discussion; Acknowledgements; References; Wild and Primitive Common Bean Populations in the Germplasm Collection at the MBG-CSIC; Abstract; 1 Introduction; 2 Material and Methods; 3 Results and Discussion; 4 Conclusions; Acknowledgments; References. 4 Conclusion Acknowledgments; References; Domesticating Shrubby Native Legumes for Pastures and Natural Grasslands; Abstract; 1 Introduction; 2 Materials and Methods; 2.1 Plant Material Collection and Phenotyping; 2.2 Agronomic Characterization; 2.3 Commercialization; 3 Conclusion; References; Effects of Temperature on Growth During in vitro Embryo Culture of Field Bean (Vicia faba var. minor L.); Abstract; 1 Introduction; 2 Materials and Methods; 3 Results and Discussion; 4 Conclusions; Acknowledgements; References; Ecological and Agronomic Evaluation of Dactylis glomerata subsp. lobata. Abstract1 Introduction; 2 Material and Methods; 3 Results and Discussion; 4 Conclusion; Acknowledgements; References; Tetraploid Festuca apennina is Prone to Produce Triploid Hybrid Progeny When Crossed with Diploid Festuca pratensis; Abstract; 1 Introduction; 2 Material and Methods; 2.1 Plant material; 2.2 Cross pollination; 2.3 Germination trials and ploidy determination of progeny; 3 Results and Discussion; 4 Conclusion; References; Comparing Mitotic and Meiotic Tetraploid Red Clover Plants for Seed Yield; Abstract; 1 Introduction; 2 Materials and Methods; 3 Results and Discussion. Abstract1 Introduction; 2 Materials and Methods; 3 Results and Discussion; 3.1 Geographical and Ecological Characteristics of Dactylis glomerata subsp. lobata; 3.2 Agronomic Characteristics of Dactylis glomerata subsp. lobata; 4 Conclusion; Acknowledgments; References; Yield and Genetic Composition of Latvian Festulolium Cultivars and Breeding Material; Abstract; 1 Introduction; 2 Materials and Methods; 3 Results and Discussion; 4 Conclusion; References; Genetic Variability of the Most Important Traits in Alfalfa Cultivars Under Lithuanian Conditions; Abstract; 1 Introduction. Patterns of Spring Growth and Phenology in Natural Populations of Lolium perenne Under Contrasting Field ConditionsAbstract; 1 Introduction; 2 Material and Methods; 2.1 Plant Material and Phenotyping; 2.2 Data Analysis; 3 Results; 4 Discussion and Conclusion; Acknowledgments; References; Population Structure of Red Clover Ecotypes Collected from Europe and Asia; Abstract; 1 Introduction; 2 Materials and Methods; 3 Results and Discussion; 4 Conclusion; Acknowledgements; References; Enhancing the Sustainable Use of Lolium perenne Genetic Resources from Genebanks in Plant Breeding and Research.

Summary: "This highly illustrated introductory text helps you learn and retain key information in pharmacology--taking you from course exams and the USMLE Step 1 right through to clinical practice"-- publisher's description.

Summary: In our complex, fast changing society, health is strongly influenced by the continuously changing interactions between organisations and their employees. Three major fields contribute to health-oriented improvements of these interactions: occupational health, organizational health and public health. As currently only partial links exist amongst these fields, the book aims to explore potential synergies more systematically. Considering the high mental and social demands in a service and knowledge sector economy, the first part of the book focuses on work-related psychosocial factors. As a large proportion of inequalities in health in developed countries can be explained by inequalities in working conditions, those psychosocial factors with a particularly high public health impact are highlighted. As addressing these psychosocial factors requires to involve the organization as the key change agent, the second part covers approaches to improve public health through organizational level health interventions. The last section takes a look into the future of occupational, organizational and public health: what are the future challenges regarding occupational health and how can they be tackled within and beyond the organizational level. Overall, this integrating book will help to broaden the evidence-base, legitimacy and efficacy of occupational- and organizational-level health interventions and thus increase their public health impact.

Contents:
Part I: Psychosocial Factors in Occupational and Organizational Health: A Key Public Health Issue
Social Inequalities in Work and Health in a Globalized Economy
Towards Organizational Health: Stress, Positive Organizational Behavior, and Employee Well-Being
A Critical Review of the Job Demands-Resources Model: Implications for Improving Work and Health
The Role of Psychosocial Factors in Musculoskeletal Disorders
The Impact of Social Capital on the Health and Performance of Organizations
Part II: Improving Public and Organizational Health
Capacity Building as a Key Mechanism of Organizational Health Development
Systemic Consulting for Organizational Health Development: Theory and Practice
Improving Organizational Health: The Case of Health Promoting Hospitals
Integration of Work and Personal Life as a Key Factor for Individual, Organizational and Public Health
Part III: Beyond Organizational Health: Social and Political Issues
Mental Health as a Complete State: How the Salutogenic Perspective Completes the Picture
Recovery from Work During Off-Job Time
Beyond Paid Work: Voluntary Work and its Salutogenic Implications for Society
Policy Approaches to Occupational and Organizational Health.

Summary: "Brief dynamic therapy is a time-efficient treatment in which the therapist maintains a focus on specific client issues and goals, all within a basic psychodynamic framework. Common characteristics of these approaches include time management, defined focus, circumscribed goals, active therapist participation, rapid assessment, prompt intervention, an awareness of unconscious processes, and techniques that quickly foster a strong alliance with the client. This concise volume focuses largely on one popular model in particular: time-limited dynamic psychotherapy (TLDP). TLDP is an integrative approach that uses techniques from attachment theory, interpersonal neurobiology, affective-experiential learning, and systems orientations to help clients with long-standing, dysfunctional ways of relating to others. The author explores this integrative, culturally-sensitive approach, its theory, history, the therapy process, primary change mechanisms, empirical basis, and future developments. This revised edition includes updated case examples, as well as a wealth of new research findings -- including process-outcome studies -- that affirm treatment effectiveness, explain how alliance ruptures are repaired, and new research on the "reconsolidation process" that demonstrates how sudden, dramatic change happens in brief dynamic therapy"--The publisher.

Contents:
History
Theory
The therapy process
Evaluation
Future developments.

Summary: Targets of bullying are often the most vulnerable members of the scientific workforce -- they may be low-paid graduate students or postdocs, living in a foreign country, navigating a foreign language and culture, and whose immigration status is tied directly to their employment. They may also have young families, be living paycheck-to-paycheck, and have health insurance and other benefits that depend on a contract position that can be revoked with little to no notice or cause. Finally, targets on the low end of a power differential are not likely to be supported by their institutions, particularly institutions that rely on the big grant earnings brought in by senior "bullies." The main focus of this book is to provide a brief guide regarding the cause and solution to academic bullying.

Contents:
Foreword
Chapter 1: You Are a Target, Not a Victim
Chapter 2: A Sample Target Story
Chapter 3: Causes of Abusive Supervision: The Case of Bullying in Academic Science
Chapter 4: Targets’ Responses to Abusive Supervision
Chapter 5: Mobbing in Academia
Chapter 6: What to Expect After Speaking Up?
Chapter 7: Possible Solutions to Academic Bullying in Higher Education
Chapter 8: Epilogue
Index.

Summary: Brief Integrated Motivational Intervention provides clinicians and specialist practitioners with a brief, evidence-based treatment approach for motivating clients, who have comorbid mental health and alcohol and drug misuse. -Combines CBT, motivational interviewing, and the authors' own cognitive- behavioural integrated treatment (C-BIT) to engage clients in meaningful dialogue for change -Utilizes the short 'window of opportunity' when clients are admitted to psychiatric hospital or have recently relapsed, and helps clinicians to maximize the potential of this 'teachable moment' -Helpful tools such as session-specific content, illustrative case material and easy-to-use worksheets facilitate implementation of the approach across a range of settings including inpatient, community, and residential -Developed by an expert team with many years of experience in both research and practice in the fields of psychosis and addiction.

Contents:
Brief Interventions for Psychosis: Overview and Future Directions
Integrated Pathways of Care for Psychosis: An Overview
Brief Cognitive Behavior Therapy for Psychosis
Avatar Therapy for Rrefractory Auditory Hallucinations
Yoga and Mindfulness Based Cognitive Therapy for Psychosis (Y- MBCTp©): A Pilot Study on its Efficacy as Brief Therapy
Brief Treatment of Psychosis from a Developmentally Informed Psychoanalytic Perspective
Application of Motivational Interviewing in Working with Psychotic Disorders
Brief Family nterventions in Psychosis: A Collaborative, Resource-Oriented Approach to Working with Families and Wider Support Networks
Recovery Related Brief Interventions for Psychosis
Employment support for people with psychosis
Cultural Factors in the Treatment of Psychosis
Brief Intervention Models in Psychosis for Developing Countries (Asia & Africa)
Policy Implications in Psychosis.

Summary: This book offers an introduction to aquaculture sciences and fisheries, discussing the concepts and basic characteristics of fisheries, fishery resources and the related industries, as well as the status of fisheries in various countries around the globe. The book also examines aquaculture, aquatic product processing and utilization, fishery information technology, and fishery economics and management, in addition to hot topics such as blue growth in fisheries, carbon sink fisheries, and global environmental changes in the context of fisheries. Given its scope, it is a valuable resource for undergraduate students in the field as well professional requiring a basic understanding of fisheries.

Contents:
Chapter I Preface
Section 1 Definition and Characteristics of Fisheries
1,Definition and classification of fisheries
2,Characteristics of fishery resources
3,Characteristics of the fisheries industry
Section 2 About this book
1,Aim and scope
2,Research content of this book
3, Curriculum and Related Contents
Section 3 Purpose of Introduction to Fisheries and its Role in Fisheries
1,Purpose and Significance of Learning Introduction to Fisheries 2,Role and position of fisheries in the national economy and society
Section 4 The Role of Fisheries in the National Economy and Society
1,Fisheries provide people with a rich source of protein
2,Direct contribution of fisheries to national economic development
3,Increasing National Fiscal and Foreign Exchange Income from Fisheries
4,Fisheries are conducive to arranging the rural labour force and providing social employment rate
5,Contribution of fisheries to global sustainable development and aquatic ecosystems
6,Contribution of fisheries to the development of other industries
Chapter II World Fisheries
Section 1 Overview of the State of World Fisheries Development
1, Overview of World Fisheries
2, Overview of the world fishing industry
3, Overview of the world aquaculture industry
4, Overview of world fisheries employment and fleets
5, State of the world's marine fishery resources
6, Overview of World Processing and Utilization of Aquatic Products
7, Overview of World Trade in aquatic products
8, Overview of world fisheries management
Section 2 Distribution of Major Fishery Resources and Fishery Areas in the World
1, Classification of major habitats of fishery resources such as fish
2, Division of the world's fishing areas
3, Resources of the world's inland waters and types of fisheries
Section 3 Evolution and Structural Changes in World Fisheries Production
1, Evolution of world fisheries production
2, Changes in the production structure of the world's fisheries
Section 4 World Ocean Fishing
1, Main target groups of the world's marine fisheries
2, Development and utilization of fishery resources in various sea areas of the world
Section 5 World Aquaculture
1, Main target groups for world aquaculture 2, World Aquaculture Development
Section 6 World Aquatic Processing and Utilization Industry
1, World Status of Aquatic Products Processing and Utilization
2, Status of by-product use of fisheries
3, World Trends in the Processing and Utilization of Aquatic Products
Section 7 Modern Leisure Fisheries
1, Concepts and Forms of Leisure Fisheries
2, Overview of leisure fisheries development
3, International Management and Development of Leisure Fisheries
Section 8 World Trade in Fishery Products
1, Status and status of World Trade in fishery products in international trade
2, Countries that trade in the world's major fish products
3, World consumption of fish products
4, Major fisheries products in world trade
5, Trends in world trade in fish products
Section 9 Status and trends in international fisheries management
1, Overview of the international fisheries management development process
2, Analysis of trends in international fisheries management
3, Nature, categories and functions of major international fisheries organizations
Section 10 Major problems and trends in world fisheries
1, Main Problems in the World's Fisheries
2, Future trends in international fisheries
Chapter III Overview of the world's major fishing nations
Section 1 China Fisheries and
Section 2 Japan Fisheries
Section 3 The United States Fisheries
Section 4 Indonesia Fisheries
Section 5 India Fisheries
Chapter V Overview of Major Fisheries Studies
Section 1 Overview of Fishing Science
1, The concept and research content of fishing science
2, Research Status and Development Trend of Fishing Science
Section 2 Overview of Fisheries Resources
1, The Concept and Research Content of Fisheries Resources
2, Research Status and Development Trend of Fisheries Resources
Section 3 Aquatic Growth and Culture
1, The Concept and Research Content of Aquatic Cultivation 2, Research Status and Development Trend of Aquatic Growth and Breeding
Section 4 An Overview of the Processing and Utilization of Aquatic Products
1, The concept of processing and utilization of aquatic products and its research content
2, Research status and development trend of aquatic products processing and utilization
Section 5 Overview of Fisheries Information Technology
1, The Concept of Fisheries Information Technology and its Research Contents
2, Research Status and Development Trend of Fisheries Information Technology
Section 6 Overview of fisheries economics
1, The Concept of Fisheries Economics and Its Research Contents 2, Research Status and Development Trend of Fisheries Economics
Section 7 Overview of Fisheries Resources Economics
1, The Concept of the Economics of Fishery Resources and Its Research Contents
2, Research Status and Development Trend of Fisheries Resources Economics
Chapter VI Sustainable Development of Fisheries
Section 1 Overview of Sustainable Development Theory
1, From economic growth to sustainable development
2, The concept of sustainable development
Section 2 The Sustainable Use of Fishery Resources
1, The basic reason and model of change of fishery resources
2, The general process of exploitation and utilization of fishery resources and the reason of decline based on economics
3, The concept and connotation of sustainable utilization of fishery resources
Section 3 International Action for Sustainable Development of Fisheries- Blue Growth
1, Overview of the 2030 Agenda for Sustainable Development
2, Agenda 2030 and sustainable fisheries development
3, Progress in international action for the sustainable development of fisheries
4, Blue Growth
Section 4 Assessment of the sustainable use of fishery resources in global marine areas
1, Changes in the average trophic level of global catches
2, Potential change mechanisms of MTL
3, Impact of Fisheries Development Process on the Effectiveness of 3.25 MTL Indicators
Section 5 Carbon Sink Fisheries
1, The concept of carbon sink fisheries and its role
2, Carbon sinks in marine fisheries and their development strategies
Chapter VII Global environmental change and fisheries
Section 1 Overview of Global Environmental Change
1, Eutrophication
2. Global warming
3, Destruction of the ozone layer
4, Ocean acidification
Section 2 Impact of major global environmental change events on fisheries
1, the effects of eutrophication on fisheries
2, Impact of global warming on fisheries
3, Effects of ozone layer destruction on fisheries
4, Ocean acidification and its impacts on fisheries
Section 3 Global Climate Change and Marine Ecosystems
1, Changes in fisheries in different marine ecosystems
2, High latitude spring water bloom system
3, Coastal boundary systems
4, Upstream System on the Western Boundary
5, Equatorial upwelling system
6, semi-enclosed sea
7, Sub-tropical circulation
Section 4 Impact of Global Climate Change on Aquaculture
1, Overview of global climate change impacts on aquaculture
2, Vulnerability of climate change to aquaculture by region, country and species
3, International actions to reduce the impact of climate change on aquaculture
Section 5 Vulnerability assessment of food security under the impacts of climate change on marine fisheries
References.

Contents:
1. The psychoanalytic background
2. Themes and variations in brief psychodynamic psychotherapy
3. A first case history
4. A second case history
5. The Treatment Manual
6. Therapeutic dialogues I
7. The Adherence Manual
8. Therapeutic dialogues II
9. Is Brief Psychoanalytic Therapy distinctive? A research study
10. The course of treatment
11. The place of Brief Psychoanalytic Therapy.

Summary: Bright Futures is a set of principles, strategies, and tools for use in improving the health and well-being of all children (newborn-21) through culturally appropriate interventions addressing current and emerging health promotion needs.

Contents:
What is Bright Futures? An introduction to the fourth edition of Bright Futures: guidelines for health supervision of infants, children, and adolescents
Who can use Bright Futures?
How is Bright Futures organized?
Implementing Bright Futures
Using Bright Futures to improve the quality of care
Bright futures health promotion themes
An introduction to the Bright Futures health promotion themes
Promoting lifelong health for families and communities
Promoting family support
Promoting health for children and youth with special health care needs
Promoting healthy development
Promoting mental health
Promoting healthy weight
Promoting healthy nutrition
Promoting physical activity
Promoting oral health
Promoting healthy sexual development and sexuality
Promoting the healthy and safe use of social media
Promoting safety and injury prevention
Bright futures health supervision visits
Introduction to the Bright Futures health supervision visits
Evidence and rationale
Infancy visits (prenatal through 11 months)
Early childhood visits (1 through 4 years)
Middle childhood visits (5 through 10 years)
Adolescence visits (11 through 21 years)
Appendix A: World Health Organization growth charts
Appendix B: Centers for Disease Control and Prevention growth charts
Appendix C: Bright Futures/American Academy of Pediatrics recommendations for preventive pediatric health care (periodicity schedule).

Summary: This essential resource developed by multidisciplinary panels of experts in infancy, early childhood, middle childhood, and adolescent health (i.e., pediatricians, family physicians, nurse practitioners, nutritionists, mental health specialists, pediatric dentists and families), covers 12 health promotion themes including: Promoting Family Support, Promoting Healthy Weight, and more! The guidelines reflect updated AAP Recommendations for Preventive Pediatric Health Care, updates to content reflected in the 32 health supervision visits (prenatal and 31 well-child care visits). New themes include: Promoting Lifelong Health for Families and Communities; Promoting Health for Children and Youth with Special Health Care Needs; Promoting the Healthy and Safe Use of Social Media. -- Provided by publisher.

Contents:
How to use this guide
Supporting families successfully
Bright futures health promotion themes
Bright futures health supervision visits
Introduction to the bright futures health supervision visits
Prenatal visit
Newborn visit
First week visit (3 to 5 days)
1 month visit
2 month visit
4 month visit
6 month visit
9 month visit
12 month visit
15 month visit
18 month visit
2 year visit
2½ year visit
3 year visit
4 year visit
5 and 6 year visits
7 and 8 year visits
9 and 10 year visits
Early adolescence visits (11 through 14 year visits)
Middle adolescence visits (15 through 17 year visits)
Late adolescence visits (18 through 21 year visits)
Appendices. List of abbreviations
Developmental milestones for developmental surveillance at preventive care visits
Social and emotional development in middle childhood
Domains of adolescent development
Tooth eruption chart
Sexual maturity ratings.

Summary: The indispensable companion to the most current edition of the Bright Futures Guidelines for Health Supervision of Infants, Children and Adolescents, the national standard for well-child care. These updated forms and materials relate to preventive health supervision and health screening for infants, children, and adolescents.

Summary: Patient empowerment as a key component in the future of healthcare systems is the focus of this concise in-depth analysis. It begins by defining patient empowerment as a collaborative partnership linking patients, providers, and systems, and examines the roles of health literacy, provider-patient and system-patient communication, and patient-centered care in the empowerment process. Models of positive and negative empowerment identify optimum conditions when patient and provider participate in service design and delivery as well as pitfalls and risks to patient and system when goals and input are mismatched. The book also translates concepts into practice with guidelines for empowerment strategies at the provider and organization levels to improve patient outcomes and system sustainability. Included in the coverage: · Empowering healthcare organizations to empower patients · A re-design of the patient-provider partnership · Patient empowerment: a requisite for sustainability · The risks of value co-destruction in service systems · The need for enlightening and managing the dark side of patient empowerment · Disentangling the relationship between individual health literacy and patient empowerment Straightforwardly written as a call for proactive change, The Bright Side and the Dark Side of Patient Empowerment is an illuminating text for scholars interested in patient empowerment and patient engagement, policymakers and managers operating in the healthcare field, and healthcare and social care providers.

Contents:
Contextualizing Patient Empowerment
The Bright Side of Patient Empowerment
The Dark Side of Patient Empowerment.

Summary: Like other international jurisdictions, the Canadian health sector faces significant demands for change and improvement to meet the needs of the 21st Century. To achieve that goal, highly sophisticated and capable leaders are required across all dimensions of the health system. Bringing Leadership to Life in Health: LEADS in a Caring Environment examines the essence of leadership itself and what it means to be a leader in today's world. The authors describe key challenges that demand reform in the health sector, examine why better leadership is the source code for better system performance, and look at the issues that stand in the way of getting that leadership. This book describes the five domains of the Caring Environment capabilities framework: Lead Self, Engage Others, Achieve Results, Develop Coalitions, and Systems Transformation. Bringing Leadership to Life in Health: LEADS in a Caring Environment is a simple, easily accessible, and research informed book which will explain the LEADS in a Caring Environment capabilities framework that has been adopted across Canada as the foundation for health leadership talent management. This book will illustrate this framework through supportive research, relevant stories solicited from health leaders at all levels as well as the inclusion of "learning moments" to help the readers reflect on their own experiences.

Contents:
1. LEADS: A New Perspective on Leadership in Health
2. Putting LEADS in Context
3. The LEADS in a Caring Environment Capabilities Framework: The Source Code for Health Leadership
4. Learning LEADS: A Lifelong Journey
5. The LEADS in a Caring Environment framework: Lead Self
6. The LEADS in a Caring Environment framework: Engage Others
7. The LEADS in a Caring Environment framework :Achieve Results
8. The LEADS in a Caring Environment framework: Develop Coalitions
9. The LEADS in a Caring Environment framework: Systems Transformation
10. The LEADS in a Caring Environment framework as an operating system for change
11. LEADS Learning: Epilogue.

Summary: This book shows why better leadership helps meet the challenges facing health care. The focus is on the Canadian-developed LEADS in a Caring Environment framework: what it does, how it was developed and how LEADS can be a model to envision and plan change.

Contents:
Intro
Foreword
Preface
Acknowledgments
Contents
1: From Concept to Reality: Putting LEADS to Work
Introduction
Bringing Leadership to Life in Health: A Primer on LEADS
Putting LEADS to Work: A Retrospective on a New Perspective
What has Changed: Key Ideas
What Hasn't Changed: Enduring Ideas
Summary
References
2: Illuminating Leadership and LEADS
The Foundations of Modern Leadership
The Foundations of Leadership
Leadership and Context
The Democratic Context
The Organizational Context: Leadership and Culture
The Need for More Courage Defining Leadership in Health
What Leadership Isn't
Self, Interpersonal and Strategic Leadership
Distributed Leadership
Summary
Appendix: Leadership Theories
Category: Established Leadership Theories
Category: Emerging Leadership Theories
References
3: The LEADS in a Caring Environment Capabilities Framework: The Source Code for Health Leadership
LEADS in a Caring Environment
Caring
Environment
Capabilities
Framework
The Validity of LEADS: Can You Depend on It?
Construct Validity of LEADS
Face Validity of LEADS
The Ongoing Appeal of LEADS LEADS and Other National Frameworks
The United Kingdom (England)
Australia
Summary
References
4: Learning LEADS: Developing Leadership in Individuals and Organizations
Learning Leadership: Why It's Different from Learning Anything Else
Learning Leadership Means Learning Followership
Leaders Learn from Emotional Experience as Well as Practical Experience
Learning Includes Unlearning
Leadership and Learning are Indispensable to Each Other
Learning Individual Leadership: The Hero's Journey
The Hero's Journey and Experiential Learning The Ten Commandments of Individual Leadership Learning
A Disciplined Approach to Learning Organizational Leadership
Leading Practices for Developing Leadership in Organizations
Effective Features for Maximum Leadership Program Impact
Summary
References
5: The LEADS in a Caring Environment Framework: Lead Self
Introduction
Are-Self-Aware
Components of Self-Awareness
Manage Themselves
Demonstrating Emotional Intelligence
Build a Productive Leadership Mindset
Productively Balance the Demands of Personal Responsibility and Accountability
Develop Themselves Personal Mastery: A Discipline for Self-Development
A Strengths-Based Approach
Demonstrates Character
Building Character, Building Resilience
Summary
Lead Self Self-Assessment (For on-line access to self assessment tool, please visit www.LEADSglobal.ca.)
References
6: The LEADS in a Caring Environment Framework: Engage Others
Engagement in Context
Engagement and Diversity
Foster the Development of Others
Contribute to the Creation of Healthy Organizations
Health Workplaces Demand Equity, Diversity and Inclusion (Dr. Ivy Bourgeault)
Communicate Effectively

Summary: This book discusses theories that link functions to specific anatomical brain regions. The best known of these are the Broca and Wernicke regions, and these have become synonyms for the location of productive and receptive language functions respectively. This Broca-Wernicke model has proved to be such a powerful concept that is remains the predominant view in modern clinical practice. What is fascinating, however, is that there is little evidence for this strictly localist view on language functions. Modern neuroscience and numerous clinical observations in individual patients show that language functions are represented in complex and ever-changing neural networks. It is fair to say that the model is wrong, and that Broca's and Wernicke's areas in their classic forms do not exist. This is a fascinating paradox: why do neurologists and neurosurgeons continue to use these iconic language models in everyday decision-making? In this book, the author uses his background as a neurosurgeon and a neuroscientist to provide some answers to this question. The book acquaints clinicians and researchers with the many different aspects of language representation in the brain. It provides a historical overview of functional localisation, as well as insights into the misjudgements that have kept the localist doctrine alive. It creates an awareness of the need to integrate clinical observations and neuroscientific theories if we want to progress further in clinical language research and patient care.

Summary: Brody's Human Pharmacology is a well-established and much-loved textbook that guides students of medicine, pharmacology and other health professions through pharmacology from both basic and clinical perspectives. What can be a very difficult and complex topic is divided into easily digestible chapters, each of which is clearly structured from a therapeutic overview to mechanisms of action, relationships to clinical responses, pharmacokinetics, pharmacovigilance, new developments, and clinical relevance for all health professionals.

Contents:
Sect. 1: Mechanisms of drug action and therapeutic principles
Sect. 2: Chemical mediators and drugs affecting autonomic and neuromuscular synapses
Sect. 3: Drug treatment for disorders affecting the central nervous system
Sect. 4: Drug therapy for pain management
Sect. 5: Treatment of inflammatory, allergic and immunological disorders
Sect. 6: Drug treatment for cardiovascular diseases
Sect. 7: Endocrine pharmacology
Sect. 8: Chemotherapy
Sect. 9: Speical considerations.