Books

Summary: An engaging introduction to human and animal movement seen through the lens of mechanics. How do Olympic sprinters run so fast' Why do astronauts adopt a bounding gait on the moon' How do running shoes improve performance while preventing injuries' This engaging and generously illustrated book answers these questions by examining human and animal movement through the lens of mechanics. The authors present simple conceptual models to study walking and running and apply mechanical principles to a range of interesting examples. They explore the biology of how movement is produced, examining the structure of a muscle down to its microscopic force-generating motors. Drawing on their deep expertise, the authors describe how to create simulations that provide insight into muscle coordination during walking and running, suggest treatments to improve function following injury, and help design devices that enhance human performance.

Contents:
First steps
Walking
Running
Muscle biology and force
Muscle architecture and dynamics
Musculoskeletal geometry
Quantifying movement
Inverse dynamics
Muscle force optimization
Muscle-driven simulation
Muscle-driven walking
Muscle-driven running
Moving forward.

Contents:
Chapter 1. Biomechanics of the musculoskeletal system
Chapter 2. Modeling of biomedical data uncertainty
Chapter 3. Knowledge modeling in biomechanics of the musculoskeletal system
Chapter 4. Clinical applications of biomechanical and knowledge-based models
Chapter 5. Software and tools for knowledge modeling and reasoning/interference.

Summary: This book presents an account of innovative methods and, for most of them, gives direct and practical insights into how practitioners can benefit from their use in their everyday practice. It also explains how to interpret the data measured, and the underlying neuromechanical and biomechanical factors related to sports performance. Written and edited by the same researchers who proposed and validated these methods, this book not only presents innovative methods for an efficient training and testing process (most of which are based on very simple technology and data processing methods), but also discusses the associated background information. Although it is a young scientific discipline, sport biomechanics has taken on an important role in routine sports training, medicine and rehabilitation. It allows both a better understanding of human locomotion and performance and better design of training and injury prevention. In those processes, the testing of athletes is crucial, and the quality and quantity of the variables analysed directly influences the efficiency of physicians', coaches', physiotherapists' and other practitioners' interventions.

Contents:
Intro; Acknowledgements; Contents; 1 Introduction; 1.1 Optimizing Sport Performance Is like Cooking; 1.2 See the Big Picture First; 1.3 Simple Models, Simple Methods; References; Cycling; 2 Maximal Force-Velocity and Power-Velocity Characteristics in Cycling: Assessment and Relevance; Abstract; 2.1 Introduction; 2.2 Measurement of Mechanical Output (Force, Velocity and Power) During Sprint Pedaling; 2.3 Maximal Force- and Power-Velocity Relationships in Cycling; 2.3.1 Testing and Processing; 2.3.2 Meaning of the Indexes Extracted from the Relationships. 2.4 Methodological Consideration and Practical Advices2.4.1 Period of Averaging to Draw F-V or P-V Relationships and Duration of the Sprint; 2.4.2 Quality of the F-V and P-V Models: â#x80;#x9C;Calculatedâ#x80;#x9D; Versus â#x80;#x9C;Trueâ#x80;#x9D; Data; 2.4.3 Main Factors to Control that may influence Maximal Power Output; 2.5 Field Measurement in Ecological Condition; 2.5.1 Mathematical Model of Sprint Cycling; 2.5.2 Direct Measurement with Portable System; 2.6 Conclusion; References; 3 Mechanical Effectiveness and Coordination: New Insights into Sprint Cycling Performance; Abstract; 3.1 Introduction. 3.2 Torque Profile and Concept of Mechanical Effectiveness3.2.1 Production of Power over the Pedaling Cycle; 3.2.2 Mechanical Effectiveness: The Orientation of Pedal Force; 3.3 Joint-Specific Power and Interest in Inverse Dynamics; 3.3.1 Approach and Principle; 3.3.2 Information Regarding Force and Power Capabilities in Cycling; 3.4 Muscle Activity and Muscle Coordination; 3.4.1 The Specificity of Muscle Coordination in Sprint Cycling; 3.4.2 Coordination of Monoarticular and Biarticular Muscles; 3.4.3 Muscle Coordination and Torqueâ#x80;#x93;Velocity Relationship. 3.5 Practical Implications and Perspectives for Testing and Performance3.5.1 Pedaling Effectiveness, Muscle Coordination and Performance: Whatâ#x80;#x99;s the Link?; 3.5.2 Outcomes Regarding the Meaning of Forceâ#x80;#x93;Velocity and Powerâ#x80;#x93;Velocity Relationships in Cycling and Perspectives for Testing and Training; 3.6 Conclusion; References; Ballistic Movements of Upper and Lower Limbs; 4 A Simple Method for Measuring Lower Limb Force, Velocity and Power Capabilities During Jumping; Abstract; 4.1 Introduction; 4.2 Force, Velocity, Power Mechanical Profile. 4.2.1 Force-Velocity and Power-Velocity Relationships in Jumping4.2.2 Force-Velocity Mechanical Profile in Jumping; 4.3 Reference Testing Methods; 4.3.1 Methodological Considerations; 4.3.2 Laboratory Methods; 4.3.3 Field Methods; 4.3.4 Limitations of the Reference Methods; 4.4 A Simple Method for Measuring Force, Velocity and Power During Jumping; 4.4.1 Theoretical Bases and Equations; 4.4.2 Limits of the Method; 4.4.3 Validation of the Method; 4.5 Technologies and Input Measurements; 4.5.1 Jump Height; 4.5.2 Push-off Distance; 4.6 Practical Applications; 4.7 Conclusion; References.

Summary: Three decades into the epidemic, a great deal is known about HIV and its transmission, more people are living with the disease, and the virus is no longer seen as a death sentence. But new people continue to be infected with HIV each year, making prevention strategies that are medically effective and behaviorally engaging as urgent a priority as ever. Biomedical Advances in HIV Prevention: Social and Behavioral Perspectives assembles the latest improvements, barriers to implementation, and possibilities for--and challenges to--future progress. Innovations such as pre-exposure prophylaxis (antiretroviral regimens for the high-risk uninfected) and treatment as prevention (early use of ART to reduce infectiousness of new patients) are examined, as are current findings on ongoing prevention and treatment concerns. Contributors illuminate the complex realities entailing adherence, pointing out technological, behavioral, and cultural roadblocks as well as opportunities to significantly reduce infection rates.

Contents:
Part I: Advances in HIV Prevention Technologies
Advances, Promises, and Challenges in HIV Prevention
Translating Pre-Exposure Prophylaxis Evidence into Practice and Public Health Impact
Prevention Services with Persons Living with HIV
Advocating for Rectal Microbicides and Safe Lubricants
Part II: Behavioral Challenges and Opportunities
Adherence to HIV Treatment as Prevention and Preexposure Prophylaxis
Risk Compensation in Response to HIV Prevention
Mental Health and Substance Use in the Scale-Up of HIV Prevention
Substance Use Treatment in the Era of New HIV Prevention Technologies
Part III: Global Perspectives
Revolution or Evolution? What Can Approaches Based on the Use of Antiretroviral Drugs Contribute to HIV Prevention in Gay Communities in High-Income Countries?
Implementing Biomedical HIV Prevention Advances in Uganda
Implementing Biomedical HIV Prevention Advances in Thailand
Implementing Biomedical HIV Prevention Advances in Ecuador and Peru.

Summary: Focused more specifically on the recent advances in applications of various metals and their complexes used in biomedicine, particularly in the diagnosis and treatment of chronic diseases. The editors give equal importance to other key aspects such as toxicological issues and safety concerns. The application of metals in the biomedical field is highly interdisciplinary and has a broad appeal across all biomedical specialties. Biomedical Applications of Metals is particularly focused on covering the role of metals in medicine and the development of novel therapeutic products and solutions in the form of alternative medicines, and some topics on Indian traditional medicine i.e., "Ayurveda." In Section I, the book discusses the role of metals in medicines and include chapters on nanoparticles, noble metals, medical devices, copper. selenium, silver, and microbial pathogens; while Section II includes topics on metals toxicity including heavy metals, carcinogens, cancer therapy, Bhasma's and chelating agents used in Ayurveda, and biochemical and molecular targets including actions of metals. These new and emerging concepts of applications of metals in medicine, their crucial role in management of microbial resistance, and their use in the treatment of various chronic diseases is essential information for toxicologists, and clinical and biomedical researchers.

Contents:
Part 1: Applications of Metals in Medicine
Noble Metals in Pharmaceuticals: Applications and Limitations
The Intriguing Potential of "Minor" Noble Metals: Emerging Trends and New Applications
Metal-on-Metal Hip Total Hip Arthroplasty: Progress and Problems
Copper in Medicine: Perspectives and Toxicity
Silver: Biomedical Applications and Adverse Effects
The Potential of Metals in Combating Bacterial Pathogens
Platinum in Biomedical Applications
Metal-Based Drugs for Treatment of Malaria
Metal Based Therapy in Traditional and Modern Medicine System and Cancer Therapy: Implications and Limitations
Mechanism of Action of Anticancer Metallodrugs
Part 2: Toxicity of Metals
Toxicity of Bhasmas and Chelating Agents of Ayurveda
The Flop Side of Using Heavy Metal (oids)s in the Traditional Medicine: Toxic Insults and Injury to Human Health
Impact of Heavy Metal Carcinogens on Human Health
Biochemical and Molecular Targets of Heavy Metals and Their Actions.

Summary: This textbook provides essential knowledge for biomedical product development, including material properties, fabrication processes and design techniques for different applications, as well as process design and optimization. This book is multidisciplinary and readers can learn techniques to apply acquired knowledge for various applications of biomedical design. Further, this book encourages readers to discover and convert newly reported technologies into products and services for the future development of biomedical applications. This is an ideal book for upper-level undergraduate and graduate students, engineers, technologists, and researchers working in the area of biomedical engineering and manufacturing. This book also: Provides a comprehensive set of fundamental knowledge for engineering students and entry level engineers to design biomedical devices. Offers a unique approach to manufacturing of biomedical devices by integrating and formulating different considerations in process design tasks into optimization problems. Provides a broad range of application examples to guide readers through the thinking process of designing and manufacturing biomedical devices, from basic understanding about the requirements and regulations to a set of manufacturing parameters.

Contents:
Intro; Preface; Acknowledgments; Contents; About the Authors;
Chapter 1: Introduction to Biomedical Devices; 1.1 Overview of Biomedical Devices; 1.2 Biomedical Device Industry; 1.3 Regulatory Issues; 1.4 The Demands for Biomedical Engineers; 1.5 Human System Basics; 1.6 Surgical Tools; 1.6.1 Surgical Scalpel; 1.6.2 Surgical Sutures; 1.7 Devices for Sensory Organs; 1.7.1 Skin Devices; 1.7.2 Contact Lenses; 1.8 Cardiovascular Devices; 1.8.1 Artificial Heart Valve; 1.8.2 Pacemaker; 1.8.3 Vascular Stent; 1.9 Skeleton Devices; 1.10 Tissue Grafts; 1.11 Summary; References and Further Reading Part I: Biomaterials
Chapter 2: Basic Material Properties; 2.1 Introduction; 2.2 Solid Properties; 2.2.1 Direct Stress and Strain; 2.2.2 Stress-Strain Diagram; 2.2.3 Shear Stress and Strain; 2.2.4 Poissonś Ratio; 2.3 Thermal Properties; 2.3.1 Thermal Strain and Deformation; 2.3.2 Specific Heat Capacity; 2.3.3 Changes of Moduli of Elasticity and Rigidity with Temperature; 2.4 Fluidic Properties; 2.4.1 Viscosity; 2.4.2 Types of Flows; 2.5 Surface and Interfacial Properties; 2.5.1 Surface Roughness; 2.5.2 Friction and Lubrication at the Tool-Workpiece Interface; 2.5.3 Adhesion/Binding Strength Problem 3.4Problem 3.5; Problem 3.6; Problem 3.7; Problem 3.8; Problem 3.9; Problem 3.10; References and Further Reading;
Chapter 4: Polymers; 4.1 Overview; 4.2 Basic Characteristics; 4.3 Polymeric Synthesis; 4.3.1 Overview; 4.3.2 Addition; 4.3.3 Condensation; 4.3.4 Number- and Weight-Average Molecular Weights; 4.4 Physical Properties; 4.4.1 Relaxation, Transition, and Melt Viscosity; 4.4.2 Theory of Melting Point Depression; 4.4.3 Glass Transition as an Iso-Free-Volume State; 4.4.4 Rubbery Elasticity; 4.4.5 Relationships of Tm and Tg with Molecular Weight; 4.5 Common Polymeric Biomaterials ProblemsProblem 2.1; Problem 2.2; Problem 2.3; Problem 2.4; Problem 2.5; Problem 2.6; Problem 2.7; Problem 2.8; Problem 2.9; References and Further Reading;
Chapter 3: Metals and Alloys; 3.1 Overview; 3.2 Crystalline Characteristic of Metals; 3.2.1 Crystal Direction and Planes; 3.2.2 Line Defects and Grains; 3.3 Common Physical Properties; 3.3.1 Interatomic Attraction and Repulsion; 3.3.2 Corrosion; 3.3.3 Biocompatibility; 3.4 Metal Strengthening; 3.4.1 Work Hardening; 3.4.2 Grain Size Control; 3.4.3 Alloying; 3.5 Common Metallic Biomaterials; Problems; Problem 3.1; Problem 3.2; Problem 3.3 ProblemsProblem 4.1; Problem 4.2; Problem 4.3; Problem 4.4; Problem 4.5; Problem 4.6; Problem 4.7; Problem 4.8; Problem 4.9; Problem 4.10; References and Further Reading;
Chapter 5: Ceramics; 5.1 Overview; 5.2 General Characteristics; 5.2.1 Basic Physical Properties; 5.2.2 Porosity; 5.2.3 Fracture and Bridging Contribution; 5.2.4 Slip Dislocation; 5.2.5 Biocompatibility; 5.3 Common Bioceramics; 5.3.1 Basic Bioceramics; 5.3.2 Resorbable Ceramics; Problems; Problem 5.1; Problem 5.2; Problem 5.3; Problem 5.4; Problem 5.5; Problem 5.6; Problem 5.7; Problem 5.8; References and Further Reading

Summary: This book illustrates the significance of biomedical engineering in modern healthcare systems. Biomedical engineering plays an important role in a range of areas, from diagnosis and analysis to treatment and recovery and has entered the public consciousness through the proliferation of implantable medical devices, such as pacemakers and artificial hips, as well as the more futuristic technologies such as stem cell engineering and 3-D printing of biological organs. Starting with an introduction to biomedical engineering, the book then discusses various tools and techniques for medical diagnostics and treatment and recent advances. It also provides comprehensive and integrated information on rehabilitation engineering, including the design of artificial body parts, and the underlying principles, and standards. It also presents a conceptual framework to clarify the relationship between ethical policies in medical practice and philosophical moral reasoning. Lastly, the book highlights a number of challenges associated with modern healthcare technologies.

Contents:
Chapter 1. Basic Overview of Human Physiology
Chapter 2. Basics of Bioelectronics. Collection methods
Chapter 3. Overview of Medical Physics
Chapter 4. Biosensors and Transducers
Chapter 5. Biomaterials and its medical applications
Chapter 6. Bioinstrumentation and its design aspects
Chapter 7. Techniques related to disease diagnosis and therapeutics
Chapter 8. Biosignals and its significance
Chapter 9. Medical imaging and image processing
Chapter 10. Pathophysiology of diseases causing physical disability
Chapter 11. Rehabilitation engineering
Chapter 12. Robotics and its applications
Chapter 13. Calibration, repair and safety aspects
Chapter 14. Medical ethics and policies
Chapter 15. Modern diagnostics tools.

Summary: As its title suggests, this innovative book has been written for life scientists needing to analyse their data sets, and programmers, wanting a better understanding of the types of experimental images life scientists investigate on a regular basis. Each chapter presents one self-contained biomedical experiment to be analysed. Part I of the book presents its two basic ingredients: essential concepts of image analysis and Matlab. In Part II, algorithms and techniques are shown as series of 'recipes' or solved examples that show how specific techniques are applied to a biomedical experiments like Western Blots, Histology, Scratch Wound Assays and Fluoresence. Each recipe begins with simple techniques that gradually advance in complexity. Part III presents some advanced techniques for the generation of publication quality figures. The book does not assume any computational or mathematical expertise.

Contents:
The basic ingredients
Introduction to images
Introduction to color
Western blots
Scratch wound assays
Microscopy
Analysing fluorescent cells
Creating publication quality figures from MATLAB.

Contents:
Overview of biomedical image understanding methods / Wei Xiong, Jierong Cheng, Ying Gu, Shimiao Li and Joo Hwee Lim
Medical image segmentation and its application in cardiac MRI / Dong Wei, Chao Li and Ying Sun
Retinal vascular measurements with VAMPIRE / Emanuele Trucco, Andrea Giachetti, Lucia Ballerini, Devanjali Relan, Alessandro Cavinato and Tom MacGillivray
Analyzing cell and tissue morphologies using pattern recognition algorithms / Hwee Kuan Lee, Yan Nei Law, ChaoHui Huang and Choon Kong Yap
3D nonrigid image registration by Parzenwindow based normalized mutual information / Rui Xu, YenWei Chen, Shigehiro Morikawa and Yoshimasa Kurumi
2D/3D image registration for endovascular abdominal aortic aneurysm (AAA) repair / Shun Miao and Rui Liao
Motion tracking in medical images / Chuqing Cao, Chao Li and Ying Sun
Blood smear analysis and malaria infection detection from blood cell images / Wei Xiong, SimHeng Ong, Joo Hwee Lim, Jierong Cheng and Ying Gu
Liver tumor segmentation using SVM framework and pathology characterization / Jiayin Zhou, Yanling Chi, Weimin Huang, Wei Xiong, Wenyu Chen, Jimin Liu and Sudhakar K. Venkatesh
Benchmarking lymph node metastasis classification for gastric cancer staging / Su Zhang, Chao Li, Shuheng Zhang, Lifang Pang and Huan Zhang
The use of knowledge in biomedical image analysis / Florence Cloppet
Active shape model for contour detection of anatomical structure / Huiqi Li and Qing Nie.

Summary: This 5th edition of this essential textbook continues to meet the growing demand of practitioners, researchers, educators, and students for a comprehensive introduction to key topics in biomedical informatics and the underlying scientific issues that sit at the intersection of biomedical science, patient care, public health and information technology (IT). Emphasizing the conceptual basis of the field rather than technical details, it provides the tools for study required for readers to comprehend, assess, and utilize biomedical informatics and health IT. It focuses on practical examples, a guide to additional literature, chapter summaries and a comprehensive glossary with concise definitions of recurring terms for self-study or classroom use. Biomedical Informatics: Computer Applications in Health Care and Biomedicine reflects the remarkable changes in both computing and health care that continue to occur and the exploding interest in the role that IT must play in care coordination and the melding of genomics with innovations in clinical practice and treatment. New and heavily revised chapters have been introduced on human-computer interaction, mHealth, personal health informatics and precision medicine, while the structure of the other chapters has undergone extensive revisions to reflect the developments in the area. The organization and philosophy remain unchanged, focusing on the science of information and knowledge management, and the role of computers and communications in modern biomedical research, health and health care.

Contents:
Biomedical Informatics: The Science and the Pragmatics
Biomedical Data: Their Acquisition, Storage, and Use
Biomedical Decision Making: Probabilistic Clinical Reasoning
Cognitive Science and Biomedical Informatics
Computer Architectures for Health Care and Biomedicine
Software Engineering for Health Care and Biomedicine
Standards in Biomedical Informatics
Natural Language Processing in Health Care and Biomedicine
Biomedical Imaging Informatics
Ethics and Biomedical and Health Informatics: Users, Standards, and Outcomes
Evaluation of Biomedical and Health Information Resources
Electronic Health Record Systems
The Health Information Infrastructure
Management of Information in Health Care Organizations
Patient-Centered Care Systems
Public Health Informatics
Consumer Health Informatics and Personal Health Records
Telehealth
Patient Monitoring Systems
Imaging Systems in Radiology
Information Retrieval and Digital Libraries
Clinical Decision-Support Systems
Computers in Health Care Education
Bioinformatics
Translational Bioinformatics
Clinical Research Informatics
Health Information Technology Policy
The Future of Informatics in Biomedicine.

Summary: Biomedical Natural Language Processing" is a comprehensive tour through the classic and current work in the field. It discusses all subjects from both a rule-based and a machine learning approach, and also describes each subject from the perspective of both biological science and clinical medicine. The intended audience is readers who already have a background in natural language processing, but a clear introduction makes it accessible to readers from the fields of bioinformatics and computational biology, as well. The book is suitable as a reference, as well as a text for advanced courses in biomedical natural language processing and text mining.

Contents:
1. Introduction to natural language processing
2. Historical background
3. Named entity recognition
4. Relation extraction
5. Information retrieval/document classification
6. Concept normalization
7. Ontologies and computational lexical semantics
8. Summarization
9. Question-answering
10. Software engineering
11. Corpus construction and annotation
References
Index.

Contents:
Contemporary laser surgical procedures in the head and neck
Advanced therapeutic concepts of light therapy
Photodynamic therapy
Optical diagnostics: introduction.

Summary: This textbook covers all the steps in manufacturing a biomedical product from bench to bedside. It specifically focuses on quality assurance and management and explains the different good practice principles in the various phases of product development as well as how to fulfill them: Good laboratory practice, good manufacturing practice and good clinical practice. It provides readers with the know-how to design biomedical experiments to ensure quality and integrity, to plan and conduct standard preclinical studies and to assure the quality of the final manufactured biomedical products. Importantly, it also addresses ethical concerns and considerations. The book discusses the guidelines and ethical considerations for preclinical and clinical studies, to allow readers to identify safety concerns regarding biomedical products and to improve pre-clinical studies for the development of better products. This textbook is a valuable guide for biomedical students (B.Sc., M.S., and Ph.D. students) in the field of molecular medicine, medical biotechnology, stem cell research and related areas, as well as for professionals such as quality control staff, tissue bankers, policy-makers and health professionals.

Contents:
1. An Introduction to Biomedical Product Development
2. Basic Essentials and Applications of Quality Management System (QMS) in Biomedical Sciences
3. Principles of Good Laboratory Practice (GLP)
4. Design of Experimental Studies in Biomedical Sciences
5. Preclinical Studies for Development of Biomedical Products
6. Principles of Good Manufacturing Practice (GMP)
7.The importance of Cleanroom facility in manufacturing of biomedical products
8. Safety concerns and requirement of cell based products for clinical application
9. Standards and regulatory frameworks (for cell and tissue based products)
10. Principles of Good clinical Practice (GCP)
11. Design, performance and monitoring of clinical trials
12. Good Clinical Practice: Guidelines and Requirement
13. Ethical Considerations of Biomedical Products Development.

Contents:
Foreword
PART 1: Basic considerations
1. So do you really want to pursue research?
2. What's in store: The brighter side of medical research
3. What's in store: The darker side of medical research
4. One degree of separation
5. Choosing and working with a mentor
6. Identifying a research niche you can call your own
7. Useful Definitions
PART 2: Research Foundations and Structures
8. The Institutional Review Board: Do's, Don'ts, and Nevers...
9. Animal Care and Use Committees
10. Research beyond humans and vertebrates
11. Hiring Research Staff
12. Strategy and Tactics: Running a Successful Laboratory
13. Everything you ever wanted to know about collaboration Part 3: Successful Paper and Grant Writing
14. Writing a successful research paper. I
Up to the point of submission
15. Writing a successful research paper. II
Revising, resubmitting, and post-acceptance tasks
16. Funding: An overview
17. Where to apply for funding: making the right choices
18. Writing a winning grant application
19. Grant budgeting
20. Grant writing: Pearls and lumps of coal
21. Research Training, Fellowship, and Career grants
22. Grant review from the inside
23. Interpreting your reviews
24. To resubmit or not resubmit and how to do it
Part 4: Good presentations, conferencing, networking, and other useful tools
25. The art of good presentation
26. Effective conferencing
27. Networking in the 21st century
28. Conflicts of interest
29. Scientific conduct and misconduct: what is right and proper, what is not, and what is somewhere in the middle
30. Article review and reading: being efficient and as thorough as you need to be
31. Patents
32. Working with industry
Part 5: Career choices and life lessons
33. Jobs in biomedical science: seeking, landing, and changing
34. Academic Promotion and Titles
35. On being a mentor
36. Yardsticks of success
37. Research Life Lesson #1: Everything takes longer than you think, so plan for it
38. Research life lesson #2: A person's research is endlessly important to them
39. Research Life lesson #3: Balance, timing, cycles and seeing the big picture
40. Research Life Lesson #4: Your career is an ultramarathon, not a sprint
41. Conclusion: Nothing satisfies like meaningful work
Acknowledgements.

Summary: "Biomedical research is the first step towards the creation of new medications and treatments that help to manage different types of health conditions and diseases. The prevention and cure of diseases would be practically impossible without such type of research. Although, the drug discovery and development process are far too costly, time-consuming, prone to failure and low success rate, now-a-days the term "translational research or medicine" seems to have become trendy, yet it is insufficient. The present book is a sincere attempt by dedicated researchers with an ideology to cover the importance of translational biomedical research, medicine, and disease, most importantly, basic, and clinical difficulties in the translation of diagnostic measures, pharmaceutical advances, biomarkers, diagnostics, and therapeutics. This book is meant for researchers, scientists, healthcare professionals, industry, innovators, and students of biomedical sciences, as well as basic sciences, biochemistry, biotechnology, biophysics, and life sciences in general. The volume is comprehensively covers emerging technologies for health care, various aspects of biomedical research towards understanding of pathophysiology of the diseases, advances in improvement in diagnostic procedures and therapeutic tools, the fundamental role of biomedical research in the development of new medicinal products"-- Provided by publisher.

Summary: This book provides an interdisciplinary look at emerging trends in signal processing and biomedicine found at the intersection of healthcare, engineering, and computer science. It examines the vital role signal processing plays in enabling a new generation of technology based on big data, and looks at applications ranging from medical electronics to data mining of electronic medical records. Topics covered include analysis of medical images, machine learning, biomedical nanosensors, wireless technologies, and instrumentation and electrical stimulation. Biomedical Signal Processing: Innovation and Applications presents tutorials and examples of successful applications, and will appeal to a wide range of professionals, researchers, and students interested in applications of signal processing, medicine, and biology. Presents an interdisciplinary look at research trends in signal processing and biomedicine; Promotes collaboration between healthcare practitioners and signal processing researchers; Includes tutorials and examples of successful applications.

Contents:
Chapter 1. Multi-class fNIRS Classification of Motor Execution Tasks with Application to Brain Computer Interfaces
Chapter 2. A Comparative Study of End-to-End Discriminative Deep Learning Models for Knee Joint Kinematic Time Series Classification
Chapter 3. Nonlinear Smoothing of Data with Random Gaps and Outliers (DRAGO) Improves Estimation of Circadian Rhythm
Chapter 4. Wearable Smart Garment Devices for Passive Biomedical Monitoring
Chapter 5. Spatial Distribution of Seismocardiographic Signals
Chapter 6. Noninvasive Vascular Blood Sound Monitoring Through Flexible Pvdf Microphone
Chapter 7. Fast Automatic Artifact Annotator for EEG Signals Using Deep Learning
Chapter 8. Objective evaluation metrics for automatic classification of EEG events.

Summary: This book is written in a very easy-to-follow format, and explains the key concepts of biomedical statistics in a lucid yet straightforward manner. It explains how mathematical and statistical tools can be used to find answers to common research questions. In addition, the main text is supplemented by a wealth of solved exercises and illustrative examples to aid in comprehension. Given its content, the book offers an invaluable quick reference guide for graduating students and can be very helpful in their examination process. At the same time, it represents a handy guide for medical and paramedical teachers, post-graduate medical students, research personnel, biomedical scientists and epidemiologists.

Contents:
Chapter 1. Applications of Statistics
Chapter 2. Statistical Terms
Chapter 3. Data Types
Chapter 4. Data Classification
Chapter 5. Data Presentation
Chapter 6. Measures of Central Tendency
Chapter 7. Measures of Location
Chapter 8. Measures of Dispersion
Chapter 9. Sampling Methods
Chapter 10. Statistical Distribution-Continuous
Chapter 11. Sampling Distribution and Hypothesis testing
Chapter 12. Test of Inference- one sample or two sample mean
Chapter 13. Test for Inference- Multiple sample comparisons
Chapter 14. Test for Inference- Categorical Data I
Chapter 15. Test for Inference- Categorical Data II
Chapter 16. Test for Inference- Correlation and Regression
Chapter 17. Non Parametric Tests
Chapter 18. Sample Size Estimation
Chapter 19. Epidemiological Studies
Chapter 20. Analysis of Diagnostic Test
Chapter 21. Demography
Chapter 22. Measures of Demography
Chapter 23. Infectious Disease Epidemiology
Chapter 24. Life Tables
Chapter 25. Introduction to Probability
Chapter 26. Random Variable and Mathematical Expectation
Chapter 27. Statistical Distribution- Discrete
Chapter 28. Univariate logistic regression- Theoretical aspects
Chapter 29. Use of Computer software for basic statistics.

Summary: "Writing today is a task that most researchers delegate to the least-seasoned member of their unit. These junior members of teams are, if anything, even more in the dark about the entire cycle of writing, submission, and revision than the rest of the team. Perversely, we treat the most challenging aspect of research as gruntwork best passed off to the individuals who cannot refuse to do it. Perhaps, if researchers knew the logistics of good writing and the gauntlets we all pass through in getting work published or funded, they would spend more time mentoring their teammates and even less time delegating"--Provided by publisher.

Contents:
Writing : the most vital and neglected skill
Writing for your reader's brain
Before you begin : getting to so what? and who cares?
Getting published : manuscripts, journals, and submissions
Getting funded : applying for grants
Collaborative writing : pass the baton
Communicating with the public.

Contents:
Biometals and Alzheimer's disease / Alexandra I. Mot, Peter J. Crouch
Copper in Alzheimer's disease / Rosanna Squitti, Maricarla Ventriglia, Mariacristina Siotto, Carlo Salustri
The role of selenium in neurodegenerative diseases / Bárbara R. Cardoso, Dominic J. Hare, Ashley I. Bush
Does HFE genotype impact macrophage phenotype in disease process and therapeutic response? / Anne M. Nixon, James R. Connor
Chemical elements and oxidative status in neuroinflammation / Michela Ferraldeschi, Silvia Romano, Maria C. Buscarinu, Arianna Fornasiero, Rosella Mechelli, Benedetta Cerasoli, Anna Pino, Sonia Brescianini, Carlo Mattei, Maria A. Stazi, Alessandro Alimonti, Marco Salvetti, Giovanni Ristori
Metals and neuroinflammation / Stephen C. Bondy
Metals and prions / David R. Brown
Manganese and neurodegeneration / Dinamene Marques Dos Santos, Michael Aschner, Ana P. Marrielha Dos Santos
Zinc in autism / Stefanie Grabrucker, Andreas M. Grabrucker
Metals and motor neuron disease / Per M. Roos
Metals and Lysosomal storage disorders / Henna Kontinnen, Katarína Lejavová, Tarja Malm, Katja M Kanninen
Developmental exposure to metals and its contribution to age-related neurodegeneration / Lucio G. Costa
Metal biology associated with Huntington's disease / Terry Jo V. Bichell, Timothy C. Halbesma, K. Grace Tipps, Aaron B. Bowman
Metal-binding to Amyloid-ss peptide / Melisa Del Barrio, Valentina Borghesani, Christelle Hureau, Peter Faller
Metals and mitochondria in neurodegeneration / Germán Plascencia-Villa, Miguel José- Yacamán, George Perry
Metal transporters in neurodegeneration / Hong Jiang
Metal imaging in the brain / David C. Dorman
Metalloregulation of protein clearance / Alejandra Ramírez Muñoz, Mark A. Greenough, Ashley I. Bush, Carlos M. Opazo
Metals and autophagy in neurotoxicitiy / Peng Su, Michael Aschner, Jingyuan Chen, Wenjing Luo
An overview of multifunctonal metal chelators as potential treatments for neurodegenerative diseases / Frank W. Lewis, David Tétard
Abnormal function of metalloprotein underlies most neurodegenerative diseases / Katja M. Kanninen, Anthony R. White.

Summary: "This volume outlines the current status in the field of biomimetic medical materials and illustrates research into their applications in tissue engineering. The book is divided into six parts, focusing on nano biomaterials, stem cells, tissue engineering, 3D printing, immune responses and intellectual property. Each chapter has its own introduction and outlines current research trends in a variety of applications of biomimetic medical materials. The biomimetic medical materials that are covered include functional hydrogels, nanoparticles for drug delivery and medicine, the 3D bioprinting of biomaterials, sensor materials, stem cell interactions with biomaterials, immune responses to biomaterials, biodegradable hard scaffolds for tissue engineering, as well as other important topics, like intellectual property. Each chapter is written by a team of experts. This volume attempts to introduce the biomimetic properties of biomedical materials within the context of our current understanding of the nanotechnology of nanoparticles and fibres and the macroscopic aspects of 3D bioprinting"--Publisher's description.

Contents:
Introduction. Overviews of biomimetic medical materials / Dipankar Das, Insup Noh
Nanomaterials as an emerging biomimetic materials. Protein cage nanoparticles as delivery nanoplatforms / Bongseo Choi, Hansol Kim, Hyukjun Choi, Sebyung Kang
Cell membrane coated nanoparticles: an emerging biomimetic nanoplatform for targeted bioimaging and therapy / Veena Vijayan, Saji Uthaman, In-Kyu Park
Graphene-based nanomaterials and their applications in biosensors / Young Jun Kim, Bongjin Jeong
Graphene-functionalized biomimetic scaffolds for tissue regeneration / Yong Cheol Shin, Su-Jin Song, Suck Won Hong, Jin-Woo Oh, Yu-Shik Hwang, Yu Suk Choi [and others]
Biomimetic materials in tissue engineering. influence of biomimetic materials on cell migration / Min Sung Kim [and others]
Biomimetic scaffolds for bone tissue engineering / Joon Yeong Park [and others]
Recent progress in vascular tissue-engineered blood vessels / Jun Chen, Grant C. Alexander, Pratheek S. Bobba, Ho-Wook Jun
Biomimetic medical materials and stem cells. microenvironmental regulation of stem cell behavior through biochemical and biophysical stimulation / Bogyu Choi, Deogil Kim, Inbo Han, Soo-Hong Lee
Decellularized tissue matrix for stem cell and tissue engineering / Jung Seung Lee, Yi Sun Choi, Seung-Woo Cho
Biomaterials for stem cell therapy for cardiac disease / Hyunbum Kim, Seung-Hyun L. Kim, Young-Hwan Choi, Young-Hyun Ahn, Nathaniel S. Hwang
Immunoresponses of biomimetic medical materials. immunomodulation of biomaterials by controlling macrophage polarization / Hyeong-Cheol Yang, Hee Chul Park, Hongxuan Quan, Yongjoon Kim
Artificial methods for t cell activation: critical tools in T cell biology and T cell immunotherapy / Kyung-Ho Roh
Regulatory T cell-mediated tissue repair / Jihye Hong, Byung-Soo Kim
Functional biomaterials. ROS-responsive biomaterial design for medical applications / Jung Bok Lee [and others]
Fibrin-based biomaterial applications in tissue engineering and regenerative medicine / Chan Ho Park, Kyung Mi Woo
Fabrication of electrochemical-based bioelectronic device and biosensor composed of biomaterial-nanomaterial hybrid / Mohsen Mohammadniaei, Chulhwan Park, Junhong Min, Hiesang Sohn, Taek Lee
Biomimetic self-assembling peptide hydrogels for tissue engineering applications / Jiaju Lu, Xiumei Wang
Bioartificial esophagus: where are we now? / Eun-Jae Chung
3-D bioprinting biomaterials. ECM based bioink for tissue mimetic 3D bioprinting / Seung Yun Nam, Sang-Hyug Park
3D bioprinting for artificial pancreas organ / Seon Jae Lee, Jae Bin Lee, Young-Woo Park, Dong Yun Lee
Intellectual properties in applications of biomimetic medical materials. current status of development and intellectual properties of biomimetic medical materials / Janarthanan Gopinathan, Insup Noh.

Contents:
Derivation and network formation of vascular cells from human pluripotent stem cells
High-throughput cell aggregate culture for stem cell chondrogenesis
Microfluidic device to culture 3D in vitro human capillary networks
Multifunction co-culture model for evaluating cell-cell interactions
Multiwell plate tools for controlling cellular alignment with grooved topography
Bioreactor cultivation of anatomically shaped human bone grafts
Determining the role of matrix compliance in the differentiation of mammary stem cells
Conjugation of proteins to polymer chains to create multivalent molecules
An assay to quantify chemotactic properties of degradation products from extracellular matrix
Biomimetic strategies incorporating enzymes into CaP coatings mimicking the in vivo environment
Fabrication of biofunctionalized, cell-laden macroporous 3D PEG hydrogels as bone marrow analogs for the cultivation of human hematopoietic stem and progenitor cells
Extracellular matrix mimetic peptide scaffolds for neural stem cell culture and differentiation
The delivery and evaluation of RNAi therapeutics for heterotopic ossification pathologies
Mimicking bone microenvironment for directing adipose tissue-derived mesenchymal stem cells into osteogenic differentiation
Cultivation of human bone-like tissue from pluripotent stem cell-derived osteogenic progenitors in perfusion bioreactors.

Summary: This open access book is the proceedings of the 14th International Symposium on Biomineralization (BIOMIN XIV) held in 2017 at Tsukuba. Over the past 45 years, biomineralization research has unveiled details of the characteristics of the nano-structure of various biominerals; the formation mechanism of this nano-structure, including the initial stage of crystallization; and the function of organic matrices in biominerals, and this knowledge has been applied to dental, medical, pharmaceutical, materials, agricultural and environmental sciences and paleontology. As such, biomineralization is an important interdisciplinary research area, and further advances are expected in both fundamental and applied research.

Contents:
Preface
Part I. Structure and analysis of biominerals
1 On the transition temperature to calcite and cell lengths for various biogenic aragonite
2 TEM study of the radular teeth of the chiton Acanthopleura japonica
3 Experimental cremation of bone
crystallite size and lattice parameter evolution
4 Effect of carbonic anhydrase immobilized on eggshell membranes on calcium carbonate crystallization in vitro
5 Proteomic Analysis of Venomous Fang Matrix Proteins of Protobothrops flavoviridis (Habu) Snake
6 Characterization of goldfish scales by vibrational spectroscopic analyses
7 Relationship between Bone Morphology and Bone Quality in Female Femurs: Implication for Additive Risk of Alternative Forced Molting
8 Spectroscopic investigation of shell pigments from the family Neritidae (Mollusca: Gastropoda)
9 3D visualization of calcified and non-calcified molluscan tissues using computed tomography
Part II Molecular and cellular regulation of biomineralization
10 Calcium Ion and Mineral Pathways in Biomineralization: a Perspective
11 Identification of barnacle shell proteins by transcriptome and proteomic approaches
12 The optical characteristics of cultured Akoya pearl are influenced by both donor and recipient oysters
13 Influence of B vitamins on proliferation and differentiation of osteoblastic bovine cell cultures; an in vitro study
14 Rice plant biomineralization: Electron microscopic study on plant opals and exploration of organic matrices involved in biosilica formation
15 DMP1 binds specifically to type I collagen and regulates mineral nucleation and growth
16 Exploration of genes associated with sponge silicon biomineralization in the whole genome sequence of the hexactinellid Euplectella curvistellata
Part III Genome-based analysis of biomineralization
17 The origin and early evolution of SCPP genes and tissue mineralization in vertebrates
Part IV Evolution in biomineralization
18 Immunolocalization of enamel matrix protein-like proteins in the tooth enameloid of actinopterygian bony fish
19 Geographical and seasonal variations of the shell microstructures in the bivalve Scapharca broughtonii
Part V Biomineralization in medical and dental sciences
20 Enhancement of bone tissue repair by octacalcium phosphate crystallizing into hydroxyapatite in situ
21 The relationship between the structure and calcification of dentin and the role of melatonin
22 Fabrication of hydroxyapatite nanofibers with high aspect ratio vialow-temperature wet precipitation methods under acidic conditions
23 Physico-chemical characterisation of the processes involved in enamel remineralisation by CPP-ACP
24 Molecular Interactions of Peptide Encapsulated Calcium Phosphate Delivery Vehicle at Enamel Surfaces
25 Preparation of random and aligned polycaprolactone fiber as template for classical calcium oxalate through electrocrystallization
Part VI Bio-inspired materials science and engineering
26 Dysprosium biomineralization by acidophilic fungus Penidiella sp. strain T9 and its application for metal recovery
27 Various shapes of gold nanoparticles synthesized by glycolipids extracted from Lactobacillus casei
28 Octacalcium phosphate overgrowth on b-tricalcium phosphate substrate in metastable calcium phosphate solution
Part VII Biominerals for environmental and paleoenvironmental sciences
29 Coral-based approaches to paleoclimate studies, future ocean environment assessment, and disaster research
30 An elemental fractionation mechanism common to biogenic calcium carbonate
31 Biomineralization of metallic tellurium by bacteria isolated from deep marine sediment in Niigata Bay Japan
32 Calcium oxalate crystals in plant communities of the southeast of the Pampean Plain, Argentina
33 Iron and calcium biomineralizations in the Pampean coastal plains, Argentina: their role in the environmental reconstruction of the Holocene
Part VIII Mollusk shell formation
34 Skeletal organic matrices in molluscs: origin, evolution, diagenesis
35 Functional Analysis on Shelk2 of Pacific Oyster
36 Mollusk shells: Does the nacro-prismatic "model" exist?
37 The Marsh's membrane: a key-role for a forgotten structure
38 Pearl production by implantation of outer epithelial cells isolated from the mantle of Pinctada fucata and the effects of blending of epithelial cells with different genetic backgrounds on pearl quality
39 Functional analyses of MMP genes in the ligament of Pinctada fucata
40 Chitin degraded by chitinolytic enzymes induces crystal defects of calcites
41 Screening for genes participating in the formation of prismatic and nacreous layers of the Japanese pearl oyster Pincatada fucata by RNA interference knockdown
42 Gene expression patterns in the mantle and pearl sac tissues of the pearl oyster Pinctada fucata
Part IX Appendix
43 Selected SEM and TEM images.

Summary: Biomolecular Interactions: Part A, Volume 166, the latest release in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics in cell biology. Each chapter is written by an international board of authors.

Contents:
What Are Bionanocomposites? / Agathe Urvoas, Marie Valerio-Lepiniec, Philippe Minard, Cordt Zollfrank
Molecular Architecture of Living Matter. Nucleic Acids / Enora Prado, Mónika Ádok-Sipiczki, Corinne Nardin
Lipids / Carole Aimé, Thibaud Coradin
Carbohydrates / Mirjam Czjzek
Proteins / Stéphane Romero, François-Xavier Campbell-Valois
Functional Biomolecular Engineering. Nucleic Acid Engineering / Enora Prado, Mónika Ádok-Sipiczki, Corinne Nardin
Protein Engineering / Agathe Urvoas, Marie Valerio-Lepiniec, Philippe Minard
The Composite Approach. Inorganic Nanoparticles / Carole Aimé, Thibaud Coradin
Hybrid Particles / Nikola Ž Knežević, Laurence Raehm, Jean-Olivier Durand
Biocomposites from Nanoparticles / Carole Aimé, Thibaud Coradin
Applications. Optical Properties / Cordt Zollfrank, Daniel Opdenbosch
Magnetic Bionanocomposites / Wei Li, Yuehan Wu, Xiaogang Luo, Shilin Liu
Mechanical Properties of Natural Biopolymer Nanocomposites / Biqiong Chen
Bionanocomposite Materials for Biocatalytic Applications / Sarah Christoph, Francisco M Fernandes
Nanocomposite Biomaterials / Gisela Solange Alvarez, Martín Federico Desimone
A Combination of Characterization Techniques / Carole Aimé, Thibaud Coradin.

Summary: This book presents the latest techniques in amputation rehabilitation and summarizes the most recent research findings in the field of bionic limb reconstruction. Divided into seven parts written by experts in the field, it provides valuable information on e.g. upper extremity injuries, psychological considerations, prosthetic engineering, and surgical and rehabilitation strategies. Illustrative figures and photos of real-life settings further assist understanding. This book is of interest not only for plastic surgeons, but also for hand surgeons, orthopedic and trauma surgeons as well as therapists, prosthetists and engineers.

Contents:
Introduction
Part I. Severe injuries of the upper extremity
Chapter 1. General Considerations on Upper Limb Amputation and its Levels
Chapter 2. Psychosocial importance of the hand, consequences of severe hand trauma, amputation and complete brachial plexus injury
Chapter 3. Inner amputations of the upper extremity
Part II. Functional restoration in upper limb amputees
Chapter 4. Body-powered prosthetic systems
Chapter 5. Mechatronic Design of Functional Prosthetic Systems
Chapter 6. Osseointegrated amputation prostheses and implanted electrodes
Chapter 7. Outcome Measures
Chapter 8. Biologic alternatives to prosthetic hand replacement
Part III . Selective nerve transfers in upper limb amputees
Chapter 9. Motor unit characteristics after selective nerve transfers
Chapter 10. Targeted muscle reinnervation in upper limb amputees
Part IV. Phantom pain in limb amputees
Chapter 11. Epidemiology and mechanisms of phantom limb pain
Chapter 12. Treatment strategies for phantom limb pain
Part V. Man-machine interfaces in prosthetics
Chapter 13. Control Strategies for Functional Upper Limb Prostheses
Chapter 14. Implantable myoelectric sensors for prosthetic control
Chapter 15. Prosthetic feedback systems
Part VI. Prosthetic replacement in patients with inner amputations
Chapter 16. Deafferentation pain following brachial plexus avulsion injuries
Chapter 17. Treatment algorithm for bionic hand reconstruction in patients with global brachial plexopathies
Chapter 18. Functional and psychosocial outcomes of bionic reconstruction and impact on quality of life, body image perception and deafferentation pain
Chapter 19. Ethical considerations and psychological evaluation in elective amputation for Brachial Plexus Injuries
Part VII. Rehabilitation in upper limb prosthetics
Chapter 20. Principles of Occupational and Physical Therapy in Upper Limb Amputations
Chapter 21. Novel technologies in upper extremity rehabilitation
Chapter 22. Conclusions and Future Outlook.

Summary: This book provides an overview on new insights in glaucoma, the latest technological developments, scientific achievements, and novel research leading to new paradigms in glaucoma diagnosis. Readers will discover a broad picture starting from theoretical perspectives in diagnostic criteria followed by practical examination and clinical interpretations while highlighting potential pitfalls and limitations in analysis. Non-invasive, modern technologies allowing visualization and quantification of various parts of the human eye are fast evolving and improving interpretation of modern diagnostic possibilities are essential to fill the gap between sophisticated equipment, complex clinical data, and the need for precision-medicine based interpretation. Issues such as the importance of intraocular, intracranial, and ocular perfusion pressures (IOP, ICP, OPP) in the pathogenesis of glaucoma; and imaging modalities for examination of the optic nerve head, retinal fiber layer, and visual field assessment in glaucoma are explored in these chapters. The problem-based learning approach presented herein offers a succinct go-to-guide to read and discover answers.

Summary: The book does not aim to constitute definite edges of the sixth sense, but it is to say here that the sixth sense is the result of a break in our present property. The present property is produced from integration of five common senses by the neuro-immuno-endocrine system. Thereby, mental representations of multisensory integration that primarily occur in the brain can reach throughout the body, including the heart and gut. Unconscious thought through synchronization between spatially distant brain networks would help break our present property. It would be a felicific calculus for society people to peek around the forgotten, but real life, corners through which the book "Biophysics and Neurophysiology of the Sixth Sense" seeks to explore.

Contents:
Intro; Preface; Contents; Chapter 1: What Would Happen If Humans Live Beyond Time?; Introduction; That Which Is Not Seen; The Unconscious-Thought Theory; The Default-Mode Network; The Information-Integration Theory; The Hypothesis of Conscious
Unconscious Prospection (CUP); An Integrated Approach to the Hypothesis of Conscious
Unconscious Prospection (CUP); Belief in the Present Time: That Which Generates the Background Noise While Thinking to About the Future; Being Out of Time: A Solution to See That Which Is Not Seen at the Present Time Distinguishing Self-Stimuli from Non-self, Role of Corollary DischargeThe Vestibular System; Proprioception as the Sixth Sense; Conclusions; References; Chapter 7: Extrasensory Perception: Concept and History; Introduction; Sense and Extra-Sense (the Sixth Sense); Proximate Origin of the Research in Extrasensory Perception; Types of Extrasensory Perception; Conclusions; References; Chapter 8: A Psychological Perspective on Extrasensory Perception; Introduction; Elementary Hallucinations; Deranged Hallucinations; Complete Hallucinations; Conclusions Interoceptive Hub and Visceromotor PredictionsModel for Interoceptive Inference Within Visceral Sensorimotor System; Conclusions; References; Chapter 5: Interoceptive Dysfunction; Interoception; Mood Disturbance; Anxiety Disorders; Depression; Autism; Addiction; Chronic Pain and Fibromyalgia; Delusional Body Border Disorders; Eating Disorders; Conclusions; References; Chapter 6: The Proprioceptive System; Introduction; The Proprioceptive System; Muscle Spindles; Golgi Tendon Organs; Joint Receptors; Free Nerve Endings; Skin Mechanoreceptors Neural Coding and PerceptionComputer Vision and Future Directions; Conclusions; References; Chapter 3: Biophysics of Vision; Image Forming Function of Visual System; Cornea; Lens; Accommodation; Pupil; Retina; Non-image Forming Functions of Visual System; Perception of Magnetic Field; Visual System and Circadian Rhythm; Pineal Gland; Melatonin: The Main Product of Pineal Gland; Other Sources of Melatonin; Other Modulators of Melatonin Secretion; Conclusions; References; Chapter 4: Cortex, Insula, and Interoception; Introduction; Insula; Amygdala; Neocortex Resonance: That Which Occurs If Being Out of TimeHow Would Entropy Change Relative to Resonance If Being Out of Time?; Conclusions; References; Chapter 2: Neurophysiology of Visual Perception; Introduction; Neuroanatomical Properties of Visual System; The Eye; The Retina; The Optic Pathways; Brain Regions and Pathways Involved in Perception; The Microstructure of the Primary Visual Cortex; Object Recognition; Perception of Form; Perception of Space; Motion Perception; Eye Movements and Perception; Adaptation; Human Gaze Control; Face Perception; The Constructive Nature of Visual Perception

Contents:
The biophysics of infection / Mark C. Leake
Single-molecule observation of DNA replication repair pathways in E. coli / Adam J.M. Wollman, Aisha H. Syeda, Peter McGlynn and Mark C. Leake
Investigating the swimming of microbial pathogens using digital holography / K.L. Thornton, R.C. Findlay, P.B. Walrad and L.G. Wilson
What is the 'minimum inhibitory concentration' (mic) of pexiganan acting on escherichia coli?--a cautionary case study / Alys K. Jepson, Jana Schwarz-Linek, Lloyd Ryan, Maxim G. Ryadnov and Wilson C.K. Poon
Evolution of drug resistance in bacteria / B. Waclaw
Using biophysics to monitor the essential protonmotive force in bacteria / Mei-Ting Chen and Chien-Jung Lo
The Type I restriction enzymes as barriers to horizontal gene transfer: determination of the DNA target sequences recognised by livestock-associated methicillin-resistant Staphylococcus aureus clonal complexes 133/ST771 and 398 / Kai Chen, Augoustinos S. Stephanou, Gareth A. Roberts, John H. White, Laurie P. Cooper, Patrick J. Houston, Jodi A. Lindsay and David T.F. Dryden
Biomechanical analysis of infectious biofilms / David Head
Designing a single-molecule biophysics tool for characterising DNA damage for techniques that kill infectious pathogens through DNA damage effects / Helen Miller, Adam J.M. Wollman and Mark C. Leake
Bacterial surfaces: front lines in host-pathogen interaction / Jane E. King and Ian S. Roberts
Biophysical approaches to bacterial gene regulation by riboswitches / Cibran Perez-Gonzalez, Jonathan P. Grondin, Daniel A. Lafontaine and J. Carlos Penedo
Bugs on a slippery plane / Dmitri O. Pushkin and Martin A. Bees
Transcription regulation and membrane stress management in enterobacterial pathogens / Nan Zhang, Goran Jovanovic, Christopher McDonald, Oscar Ces, Xiaodong Zhang and Martin Buck
How biophysics may help us understand the flagellar motor of bacteria which cause infections / Matthew A.B. Baker
Mechanics of bacterial cells and initial surface colonization / Sebastian Aguayo and Laurent Bozec
Neutron reflectivity as a tool for physics-based studies of model bacterial membranes / Robert D. Barker, Laura E. McKinley and Simon Titmuss
Mechanisms of Salmonella typhi host restriction / Stefania Spanò --Insights into biological complexity from simple foundations / L. Albergante, D. Liu, S. Palmer and T.J. Newman
Force spectroscopy in studying infection / Zhaokun Zhou and Mark C. Leake
Imaging immunity in lymph nodes: past, present and future / James Butler, Amy Sawtell, Simon Jarrett, Jason Cosgrove, Roger Leigh, Jon Timmis and Mark Coles
Novel approaches to manipulating bacterial pathogen biofilms: whole-systems design philosophy and steering microbial evolution / Alexandra S. Penn
Index.

Summary: In this monograph, the author--Head researcher at the Institute of Cell Biophysics of Russian Academy of Sciences--discusses the results of his own long-term studies of mitochondria as well as alternative points of view and experiments of other important researchers in the field. The monograph contains the main aspects of mitochondrial research by a number of physical methods: fluorescence spectroscopy, UV-vis spectrophotometry, IR spectroscopy, light-scattering, optical microscopy, fluorescence microscopy, colorimetry, photobleaching, polarography, among others. The monograph is very useful for researchers and graduate students specializing in mitochondrial biophysics, biochemistry, molecular biology and cytology. The book was published in Russian in 2019 by Photon Publishers (Pushchino, Moscow region).

Contents:
The mitochondria in the cell
Early studies
Structural features
Are there giant mitochondria and reticulum
Evolutionary origins
Reproduction of mitochondria in cell
Mitochondrial DNA
Membrane and matrix proteins
Bioenergetics
The respiratory chain
NADH-dehydrogenase
Succinate dehydrogenase
Cytochrome oxidase
Interactions in enzyme-substrate complexes
Mechanisms of electron transfer
Membrane synthesis of ATP
Proton transport and the chemiosmotic hypothesis
On the measurement of transmembrane potential
The conformational hypothesis
Thermal coupling model
Photo-respiration and photo-induced synthesis of ATP
Surface photodesorption
Flavin and ubiquinone of NADH-dehydrogenases are not involved in the transfer of electrons to artificial acceptors
The lag-period and the pseudo-oscillations in redox-reactions of NADH with DHPIP
Electron-conformational properties of the flavoprotein fragment of NADH-dehydrogenase
Resonant energy transfer from mitochondrial proteins to NADH
Flavin loss from NADH-dehydrogenase complex
Stabilization of NADH-dehydrogenase by adenosine phosphates
Dehydrogenase mitochondrial activity in the touch, determined by the decrease in tryptophan fluorescence by formosan
Rotenone-insensitive NADH oxidation by respiratory chain fragments
Cytochrome-C shunts oxidation of NADH
NADH-oxidasation mitochondrial activity in hypotension when you block the respiratory chain
Do mitochondria swell much?
Some properties of protomitochondria
Protomitochondria in liver cells
Germinal protomitochondria
Fluorimetric comparison of protomitochondria and mitochondria
Photometry and fluorimetry of protomitochondria from liver of young and adult rats.-Degradation of mitochondria to lipofuscin during heating and lighting
Production of superoxide and lipofuscin after the loss of flavin by NADH-dehydrogenase
Some properties of mitochondrial lipofuscin.

Summary: "The volume is intended as an introduction to the physical principles governing the main processes that occur in photosynthesis, with emphasis on the light reactions and electron transport chain. A unique feature of the photosynthetic apparatus is the fact that the molecular structures are known in detail for essentially all of its major components. The availability of this data has allowed their functions to be probed at a very fundamental level to discover the design principles that have guided evolution. Other volumes on photosynthesis have tended to focus on single components or on a specific set of biophysical techniques, and the authors' goal is to provide new researchers with an introduction to the overall field of photosynthesis. The book is divided into sections, each dealing with one of the main physical processes in photosynthetic energy conversion. Each section has several chapters each describing the role that a basic physical property, such as charge or spin, plays in governing the process being discussed. The chapters proceed in an orderly fashion from a quantum mechanical description of early processes on an ultrafast timescale to a classical treatment of electron transfer and catalysis on a biochemical timescale culminating in evolutionary principles on a geological timescale."--Publisher's website.

Contents:
Part I. Light Energy Capture and Energy Transfer
1. Structure-Based Calculation of Pigment-Protein and Excitonic Pigment-Pigment Coupling in Photosynthetic Light-Harvesting Complexes / Frank Müh and Thomas Renger
2. Electron-Phonon and Exciton-Phonon Coupling in Light Harvesting, Insights from Line-Narrowing Spectroscopies / Jörg Pieper and Arvi Freiberg
3. Photosynthetic Energy Transfer and Charge Separation in Higher Plants / Tjaart P.J. Krüger, Vladimir I. Novoderezhkin, Elisabet Romero, and Rienk van Grondelle
Part II. Underlying Principles of Electron Transport
4. Tunneling in Electron Transport / Christopher C. Moser
5. Spin in Photosynthetic Electron Transport / Isaac F. Céspedes-Camacho and Jörg Matysik
6. Energy Changes in Photosynthetic Electron Transport: Probing Photosynthesis by Pulsed Photoacoustics / David Mauzerall and Steven P. Mielke
Part III. Separation and Stabilization of Charge
7. Mechanism of Primary Charge Separation in Photosynthetic Reaction Centers / Sergei Savikhin and Ryszard Jankowiak
8. Effects of Quasi-Equilibrium States on the Kinetics of Electron Transfer and Radical Pair Stabilisation in Photosystem I / Stefano Santabarbara, Robert Jennings, and Giuseppe Zucchelli
9. Energetics of Cofactors in Photosynthetic Complexes: Relationship Between Protein-Cofactor Interactions and Midpoint Potentials / James P. Allen and JoAnn C. Williams
Part IV. Donor Side Intermediates and Water Splitting
10. The Radical Intermediates of Photosystem II / K.V. Lakshmi, Christopher S. Coates, Stuart Smith, and Ruchira Chatterjee
11. Structure-Function Relationships in the Mn₄CaO₅ Water-Splitting Cluster / Jian-Ren Shen
12. Water and Oxygen Diffusion Pathways Within Photosystem II. Computational Studies of Controlled Substrate Access and Product Release / Serguei Vassiliev and Doug Bruce
Part V. Evolution of the Photosynthetic Apparatus
13. From Ionizing Radiation to Photosynthesis / Alexander N. Melkozernov
14. Origin of Oxygenic Photosynthesis from Anoxygenic Type I and Type II Reaction Centers / John F. Allen.

Summary: Innovation is added value to a known process. Bioprinting: Techniques and Risks for Regenerative Medicine aims to stimulate a scientifically grounded, interdisciplinary, multiscale debate and exchange of ideas using the techniques described in the book. 3D printing and additive manufacturing evolved from within the field of Cell Biology will have the ability to recreate cells queried from large amounts of phenotypic and molecular data. Stem Cell biologists, biotechnologists and material engineers, as well as graduate students will greatly benefit from the practical knowledge and case examples provided throughout this book.

Summary: Converting biomass to biofuels involves hydrolyzing cellulose to sugars using cost-intensive commercial enzymes an expensive step that makes large-scale production economically non-viable. As such, there is a need for low-cost bioprocessing. This book critically evaluates the available bioprocessing technologies for various biofuels, and presents the latest research in the field. It also highlights the recent developments, current challenges and viable alternative approaches to reduce the overall cost of producing biofuels.

Contents:
Chapter 1. Impact of fermentation types on enzymes used for biofuels production
Chapter 2. Downstream Processing; Applications and Recent Updates
Chapter 3. Role of bioreactors in bio-fuel generations
Chapter 4. Bioprocess for Algal Biofuels Production
Chapter 5. Effect of Bioprocess Parameters on Biofuel Production
Chapter 6. Role of substrate to improve biomass to bio fuel production technologies
Chapter 7. Techno-economic analysis of second-generation bio-fuel technologies
Chapter 8. Recent advances in metabolic engineering and synthetic biology for microbial production of isoprenoid-based biofuels: an overview
Chapter 9. Applications of biosensors for metabolic engineering of microorganisms and its impact on biofuel production
Chapter 10. Recent progress in CRISPR-based technologies applications for biofuels production.

Contents:
Bioprocessing for cell based therapies
Structured methodology for process development in scalable stirred tank bioreactors platforms
The effect of scale-up on cell phenotype : compatibility testing to optimize bioreactor usage and manufacturing strategies
The scale-up of human mesenchymal stem cell expansion and recovery
Challenges of scale-up of cell separation and purification techniques
Fundamental points to consider in the cryopreservation and shipment of cells for human application
Short-term storage of cells for application in cell-based therapies
Cell therapy in practice.

Summary: This book focuses on cell culture-produced viral vaccines to meet the needs of the rapidly expanding research and development in academia and industry in the field. This book introduces the basic principles of vaccination and the manufacturing of viral vaccines. Bioprocessing of Viral Vaccines, will provide an overview of the advanced strategies needed to respond to the challenges of new and established viral infection diseases. The first few chapters cover the basics of virology and immunology as essential concepts to understand the function and design of viral vaccines. The core of the content is dedicated to process development, including upstream processing and cell culture of viral vaccines, downstream processing, and extensive analytical technologies specific to viral vaccines. Advanced process analytical technologies (PAT) and Quality by Design (QbD) concepts are also introduced in the context of vaccine manufacturing. The case studies included cover inactivated, attenuated vaccines exemplified by influenza vaccines, sub-unit vaccines exemplified by Virus Like Particles (VLPs: HPV vaccines) and sub-unit vaccines (Flublock), vectored vaccines: adenoviruses and Vesicular stomatitis Virus (VSV) vectored vaccines, genomic vaccines (DNA and mRNA) vaccines as developed for COVID-19 response in particular and a review of COVID-19 vaccines approved or in advanced clinical trials. This book is aimed at graduate engineers and professionals in the fields of vaccinology, bioprocessing, and biomanufacturing of viral vaccines.

Contents:
Bioprocessing of viral vaccines, introduction / Amine Kamen, Laura Cervera
Introduction to virology / Shantoshini Dash
Introduction to basic immunology and vaccine design / Alaka Mullick, Shantoshini Dash
Cell lines for vaccine production / Isabelle Knott [and others]
Upstream processing for viral vaccines-General aspects / Lars Pelz [and others]
Upstream processing for viral vaccines, process intensification / Sven Göbel [and others]
Downstream processing of viral-based vaccines / Rita P. Fernandes [and others]
Analytics and virus production processes / Emma Petiot
Manufacturing of seasonal and pandemic influenza vaccines, a case study / Cristina A. T. Silva [and others]
Recombinant vaccines: gag-based VLPs / Laura Cervera [and others]
Vectored vaccines / Zeyu Yang [and others]
Design and production of vaccines against COVID-19 using established vaccine platforms / Ryan Kligman [and others].

Summary: The rapid urbanization and industrialization of developing countries across the globe have necessitated for substantial resource utilization and development in the areas of Healthcare, Environment, and Renewable energy. In this context ,this resourceful book serves as a definitive source of information for the recent developments in application of microbial enzymes in various sectors. It covers applications in fermentation processes and their products, extraction and utilisation of enzymes from various sources and their application in health and biomass conversion for production of value added products. Different chapters discuss various areas of bioprospecting in enzyme technology, and describe why these are the mainstays for industrial production of value added products. The rich compilation of the cutting-edge advances and applications of the modern industrial based techniques hold feasible solutions for a range of current issues in enzyme technology. This book will be of particular interest for scientists, academicians, technical resource persons, engineers and members of industry. Undergraduate and graduate students pursuing courses in the area of industrial biotechnology will find the information in the book valuable. General readers having interest towards biofuels, enzyme technology, fermented food and value added products, phytochemicals and phytopharmaceutical products will also find the book appealing. Readers will discover modern concepts of enzymatic bioprocess technology for production of therapeutics and industrial value added products.

Contents:
Chapter 1: Application of enzymes in bioremediation of contaminated hydrosphere and soil environment
Chapter 2: Bioremediation Of Highly Toxic Hexavalent Chromium By Bacterial Chromate Reductases Family: An Structural And Functional Overview
Chapter 3: An Overview Of Raw Starch Digesting Enzymes And Their Applications In Biofuel Development
Chapter 4: Bamboo Valorization By Fermentation And Enzyme Treatment
Chapter 5: Recent Developments In Pretreatment And Enzymatic Hydrolysis For Cellulosic Bioethanol Production
Chapter 6: Production Of Biofuel From Disposed Food And Dairy Waste
Chapter 7: Role of enzymes in synthesis of nanoparticles
Chapter 8: Protein-Nanoparticle Interaction And Its Potential Biological Implications
Chapter 9: Enzyme-Nanoparticle Corona: A Novel Approach, Their Plausible Applications And Challenges
Chapter 10: Enzymes In Fuel Biotechnology
Chapter 11: Role Of Enzymes In Deconstruction Of Waste Biomass For Sustainable Generation Of Value-Added Products
Chapter 12: Thermostable Enzymes From Clostridium thermocellum
Chapter 13: Hot And Cold Bacteria Of Sikkim: Biodiversity And Enzymology
Chapter 14: Enzymes In Health Care: Cost Effective Production And Applications Of Therapeutic Enzymes In Health Care Sector
Chapter 15: Significance Of Enzymes In Modern Healthcare: From Diagnosis To Therapy
Chapter 16: L-Asparaginase And Methioninase As Prospective Anticancer Enzymes: Currentapplications And Production Approaches
Chapter 17: Production Of Thrombolytic And Fibrinolytic Proteases: Current Advances And Future Prospective
Chapter 18: Enzymes In Textile Industries
Chapter 19: Role of Enzymes in Textile Processing.

Summary: Peripheral nerve analysis is a challenging task for pathologists, given the advent of new diagnoses and techniques of analysis and the impact of molecular genetics. This book presents a simple, logical method for constructing a differential diagnosis based on pathology and clinical presentation. It also provides advice on the selection of ancillary molecular, immunohistochemical and genetic techniques to establish a definitive diagnosis. Clear, authoritative guidance is offered on diagnosis of the full range of neuropathies with the aid of a wealth of high-quality color photomicrographs and electron micrographs. The pathologist will benefit greatly from the identification of a variety of artifacts and normal structures occasionally encountered in nerve biopsies that need to be distinguished from specific pathologic alterations. This user-friendly, practical text will be an invaluable aid in achieving the most specific diagnosis possible.

Contents:
Introduction and Clinical Correlation
Normal Peripheral Nerve Structure
Basic Pathological Mechanisms
Vasculitic Neuropathy
Diabetic neuropathies
Skin Biopsies
Metabolic Neuropathies
Inflammatory and Immune-Mediated Neuropathies
Neuropathies Associated with Infectious Diseases
Amyloid neuropathy
Genetic Neuropathies
Dysproteinemias
Toxin-induced neuropathies
Miscellaneous neuropathies.

Contents:
Biopsy techniques, diagnostic methods, and reporting
Benign and intermediate fibrosing lesions
Cellular benign and intermediate lesions of fibroblasts and myofibroblasts
Cutaneous spindle cell lesions
Intra-abdominal spindle cell lesions
Smooth muscle tumors
Myofibroma, myopericytic tumors, myoepithelioma, and myofibroblastoma
Tumors of specialized lower genital tract mesenchyme
Benign nerve sheath tumors
Spindle cell sarcomas
Epithelioid tumors of soft tissue
Soft tissue lesions with clear or granular cells
Pleomorphic soft tissue tumors
Small round cell tumors
Benign adipose tissue lesions
Liposarcoma
Superficial vascular lesions and mimics of vascular lesions
Deep vascular lesions
Osteochondroid lesions of soft tissue
Superficial myxoid lesions
Deep myxoid lesions
Plexiform soft tissue tumors
Soft tissue tumors with giant cells.

Summary: "Part of the highly regarded Biopsy Interpretation Series, Biopsy Interpretation of the Bladder, 4th Edition, provides practical, highly illustrated information on the diagnosis and prognosis of the full range of biopsies of the urothelial tract. Practical, well-organized, and highly readable, this fully revised volume by Drs. Jonathan I. Epstein, Victor E. Reuter, and Mahul B. Amin addresses both common and unusual issues that arise in the day-to-day interpretation of bladder biopsies, teaching the best diagnostic practices as well as how to avoid the most common pitfalls. Helps you accurately identify all lesions, tumors, and tumor-like lesions for the bladder-from normal anatomy and histology to a wide range of both common and unusual findings Frames each diagnosis in its most common clinical context, explaining how the pathology can be used to make key clinical management decisions Presents key differential features of tumors, organized according to diagnostic category Features high-quality photomicrographs and illustrations throughout, including updated images both in print and online-nearly 500 images in all Provides access to interactive questions and answers online for self-assessment and review Incorporates the latest World Health Organization and Genitourinary Pathology Society (GUPS) classifications Enrich Your eBook Reading Experience Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech. "-- Provided by publisher.

Contents:
Normal Bladder Anatomy and Variants of Normal Histology
Flat Urothelial Lesions
Papillary Urothelial Neoplasms and Their Precursors
Urothelial Neoplasms with Inverted Growth Patterns
Invasive Urothelial Carcinoma
Histologic Variants of Urothelial Carcinoma
Morphologic, Prognostic, and Predictive Factors and Reporting of Bladder Cancer
Glandular Lesions
Squamous Lesions
Cystitis
Mesenchymal Tumors and Tumor-Like Lesions
Miscellaneous Nontumors and Tumors
Secondary Tumors of the Bladder
Biopsy of the Renal Pelvis and Ureter
Urinary Tract Cytopathology.

Contents:
Normal bladder anatomy and variants of normal histology
Flat urothelial lesions
Papillary urothelial neoplasms and their precursors
Urothelial neoplasms with inverted growth patterns
Invasive urothelial carcinoma
Histologic variants of urothelial carcinoma
Conventional morphologic, prognostic, and predictive factors and reporting of bladder cancer
Glandular lesions
Squamous lesions
Cystitis
Mesenchymal tumors and tumor-like lesions
Miscellaneous non-tumors & tumors
Secondary tumors of the bladder
Urinary tract cytopathology.

Summary: Part of the highly regarded Biopsy Interpretation Series, this new volume by Drs. Laura M. Wake, Genevieve Crane, and Michael Borowitz presents a concise, pattern-based approach to bone marrow pathology. Biopsy Interpretation of the Bone Marrow provides superbly illustrated guidance from top experts in the field, covering all aspects of bone marrow aspirates and biopsies: procurement and processing, ancillary techniques, formulation of a final diagnosis, and reporting to the clinical team. Hundreds of full-color illustrations depict the full range of benign and neoplastic processes involving the bone marrow. -- Provided by publisher.

Contents:
Normal anatomy and histology
Reactive, inflammatory, and nonproliferative lesions
Intraductal proliferative lesions : usual ductal hyperplasia, atypical ductalhyperplasia, and ductal carcinoma in situ
Columnar cell lesions and flat epithelial atypia
Lobular carcinoma in situ and atypical lobular hyperplasia
Fibroepithelial lesions
Adenosis and sclerosing lesions
Papillary lesions
Microinvasive carcinoma
Invasive breast cancer
Spindle cell lesions
Vascular lesions
Other mesenchymal lesions
Miscellaneous rare lesions
Nipple disorders
Male breast lesions
Breast lesions in children and adolescents
Axillary lymph nodes
Treatment effects
Specimen processing, evaluation, and reporting.

Contents:
Benign cysts and selected developmental anomalies
Inflammatory and infectious lesions
Diffuse gliomas
Other astrocytomas
Ependymal tumors
Other gliomas
Neuronal and mixed glioneuronal tumors
Sellar and suprasellar lesions
Meningeal lesions
Embryonal tumors
Choroid plexus tumors
Pineal region tumors
Cranial and spinal nerve tumors
Vascular malformations
Germ cell tumors
Hematolymphoid neoplasms
Select tumors of indeterminate or mesenchymal differentiation
Metastases
Intraoperative consultation
General approach and differential diagnosis.

Summary: "Part of the highly regarded Biopsy Interpretation Series, this fully revised volume provides practical, highly illustrated information on the diagnosis and prognosis of the full range of biopsies of the various tissues of the head and neck region, including the ear. Biopsy Interpretation of the Head and Neck, 3rd Edition, addresses both common and unusual issues that arise in day-to-day practice, with an emphasis on the complex area of the upper aerodigestive tract and ear. Discusses both neoplastic and non-neoplastic entities to help you arrive at an accurate diagnosis and guide patient management. Provides new information about emerging diagnostic entities and ancillary testing. Covers squamous cell carcinomas, HPV-related tumors, bony lesions, odontogenic lesions, and more"-- Provided by publisher.

Contents:
Normal Anatomy and Histology
Benign Squamous Proliferations and Neoplasms
Precursor Lesions of Squamous Cell Carcinoma
Conventional Squamous Cell Carcinoma
Histologic and Etiologic Variants of Squamous Cell Carcinoma
Salivary Gland-Type Neoplasms
Adenocarcinomas, Other Than Those That Can Be Classified as Salivary Gland-Type
Neural, Neuroectodermal, and Neuroendocrine Neoplasms
Hematopoietic and Lymphoid Disorders
Germ Cell Tumors
Soft Tissue Tumors
Bone, Cartilaginous, and Jaw Lesions That May Be Sampled With Upper Aerodigestive Tract Biopsies
Nonneoplastic Lesions of the Nasal Cavity, Paranasal Sinuses, and Nasopharynx
Nonneoplastic Lesions of the Oral Cavity
Nonneoplastic Lesions of the Larynx
Pathology of the Ear.

Contents:
General approach to biopsy assessment
General approach to biopsy reports
The almost normal liver biopsy
Liver injury patterns
Acute and chronic viral hepatitis
Other infections of the liver
Granulomatous disease
Drug effects
Fatty liver disease
Autoimmune hepatitis
Biliary tract disease and cholestatic liver disease
Pediatric cholestatic liver disease
Vascular disease
Transplant pathology
Iron overload disease
Wilson disease and other genetic diseases
Liver disease in systemic conditions
Pediatric benign and malignant tumors
Adult benign and malignant mesenchymal tumors
Benign and malignant hepatocellular tumors
Benign and malignant biliary tumors
Other tumors of the liver.

Summary: "Part of the highly regarded Biopsy Interpretation Series, Biopsy Interpretation of the Liver, 4th Edition, provides practical, highly illustrated information on the diagnosis and prognosis of the full range of biopsies of the liver. Practical, well-organized, and highly readable, this fully revised volume by Dr. Michael S. Torbenson addresses both common and unusual issues that arise in the day-to-day interpretation of liver biopsies, teaching the best diagnostic practices as well as how to avoid the most common pitfalls. Frames each diagnosis in its most common clinical context, explaining how the pathology can be used to make key clinical management decisions. Presents key differential features of tumors, organized according to diagnostic category"-- Provided by publisher.

Contents:
General Approach to Biopsy Specimens
Liver Injury Patterns
Immunohistochemistry and Special Stains in Liver Pathology
The Almost Normal Liver Biopsy
Acute and Chronic Viral Hepatitis
Other Infections of the Liver
Granulomatous Disease
Drug-Induced Liver Injury
Fatty Liver Disease
Autoimmune Hepatitis
Biliary Tract Disease and Cholestatic Liver Disease
Pediatric Cholestatic Liver Disease
Vascular Disease
Transplant Pathology
Iron Overload in the Liver
Genetic Diseases of the Liver
Liver Disease in Systemic Conditions
Cryptogenic Cirrhosis
Benign and Malignant Pediatric Tumors
Adult Benign and Malignant Mesenchymal Tumors
Hepatocellular Pseudotumors and Tumors
Benign and Malignant Biliary Tumors
Lymphoma and Metastatic Disease.

Summary: "Biopsy Interpretation of the Lung aids pathologists in accurately evaluating disease processes. It includes detailed chapters on interstitial lung disease, lung cancer, and neuroendocrine tumors. Organized by traditional disease groups, Biopsy Interpretation of the Lung provides a solid approach to formulating surgical and medical decisions."-- Provided by publisher.

Contents:
Methods for Obtaining Lung Biopsies
Inflammatory Lung Conditions
Pulmonary Noninfectious Granulomas
Lung Vasculitis and Hemorrhagic Disorders
Bacterial Lung Infections
Fungal Lung Infections
Parasitic Lung Infections
Viral Lung Infections
Interstitial Lung Disease
Lung Transplant Pathology
Lymphoid Lesions of the Lung
Epithelial Lung Neoplasms
Neuroendocrine Lung Neoplasms
Unusual Lung Tumors and Tumor-Like Conditions
Metastatic Tumors to the Lung.

Summary: "A new volume in the highly regarded Biopsy Interpretation Series, Biopsy Interpretation of the Lymph Node provides concise, abundantly illustrated information on the pathologic approach to diagnosis for these frequently encountered biopsies. Practical and well organized, this highly readable volume edited by Drs. Rebecca L. King, Anamarija M. Perry, and Lauren B. Smith, addresses both common and unusual issues that arise in the day-to-day interpretation of non-neoplastic and neoplastic lymph node biopsies, teaching the best diagnostic practices as well as how to avoid the most common pitfalls. Focusing on the daily tasks and needs of the general pathologist, it provides a solid foundation for clinical diagnostic decision making. Frames each diagnosis in its most common clinical context, explaining how the pathology can be used to make key clinical management decisions Features high-quality photomicrographs and illustrations throughout-more than 400 images in all Covers the pattern-based approach to lymph node evaluation, giving special emphasis to differential diagnosis and limitations of small biopsies Addresses diagnostic methods and ancillary studies used in lymph node pathology such as immunohistochemistry, flow cytometry, FISH, and molecular studies Provides eBook access to questions and answers for self-assessment and exam review Enrich Your eBook Reading ExperienceRead directly on your preferred device(s),such as computer, tablet, or smartphone. Easily convert to audiobook,powering your content with natural language text-to-speech. "-- Provided by publisher.

Contents:
Lymph Node Evaluation
Diagnostic Methods and Ancillary Studies
Benign Diseases Involving Lymph Node
Precursor Lymphoid Neoplasms, Myeloid Sarcoma, and Blastic Plasmacytoid Dendritic Cell Neoplasm
Mature B-cell Neoplasms
Mature T-cell Neoplasms
Classic Hodgkin Lymphoma and Nodular Lymphocyte Predominant B-cell Lymphoma
Lymphoproliferative Disorders Associated With Immunodeficiency
Histiocytic and Dendritic Cell Neoplasms.

Contents:
The normal thyroid
The classification of thyroid pathology
The cytologic approach to diagnosis of thyroid pathology : technical aspects
The histologic biopsy of thyroid : technical aspects
Ancillary tools in thyroid diagnosis
Cystic lesions
Inflammatory and lymphoid lesions
Papillary lesions
Follicular lesions
Solid and trabecular lesions
Squamoid, spindle, and giant-cell lesions
Small cell lesions.

Summary: This book summarizes recent advances in the processing of waste biomass resources to produce biofuels and biochemicals. Worldwide interest in clean energy sources, environmental protection, and mitigating global warming is rapidly gaining momentum and spurring on the search for alternative energy sources, especially for the transportation and industrial sectors. This book reviews the opportunities presented by low-cost organic waste materials, discussing their suitability for alternative fuel and fine chemical production, physicochemical characterization, conversion technologies, feedstock and fuel chemistry, refining technologies, fuel upgrading, residue management, and the circular economy. In addition, it explores applied aspects of biomass conversion by highlighting several significant thermochemical, hydrothermal and biological technologies. In summary, the book offers comprehensive and representative descriptions of key fuel processing technologies, energy conversion and management, waste valorization, eco-friendly waste remediation, biomass supply chain, lifecycle assessment, techno-economic analysis and the circular bioeconomy.

Contents:
Intro
Preface
Contents
Editors and Contributors
About the Editors
Contributors
1: Growth of Biofuels Sector: Opportunities, Challenges, and Outlook
1.1 Introduction
1.2 Biofuel Scenario in Canada and the World
1.3 Policies and Their Impacts on the Success of Advanced Biofuels: Scenario in Canada and the World
1.4 Outlook for a Sustainable Future
1.5 Conclusions
References
2: Bioconversion of Agro-industrial Residues to Second-Generation Bioethanol
2.1 Introduction
2.2 Composition of Lignocellulosic Biomass 2.3 Commonly Available Agricultural Crop Residues in the World
2.3.1 Barley and Coffee Residues
2.3.2 Sugarcane, Maize, Rice, and Wheat Residues
2.3.3 Cotton
2.3.4 Oil Palm Residues
2.3.5 Potato Residues
2.3.6 Soybean Residues
2.4 Enzymatic Saccharification of Lignocellulosic Residues
2.4.1 Cellulases
2.4.2 Auxiliary Activity 9 Enzyme and Swollenin Protein
2.4.3 Hemicellulases
2.4.4 Pectin-Degrading Enzyme System
2.4.5 Delignifying Enzymes
2.5 Bioconversion of Biomass to Second-Generation Bioethanol 2.6 Pretreatment of Lignocellulosic Biomass
2.7 Obtaining an Enzymatic Consortium
2.8 Fermentation for the Production of Second-Generation Bioethanol
2.9 Conclusions
References
3: Catalytic Transformation of Ethanol to Industrially Relevant Fine Chemicals
3.1 Introduction
3.2 Conversion of Ethanol to Small Oxygenates
3.2.1 Acetaldehyde
3.2.2 Acetic Acid and Ethyl Acetate
3.2.3 Acetone
3.3 Conversion of Ethanol to Hydrocarbons
3.3.1 Ethylene
3.3.2 Propylene
3.3.3 Butanol
3.3.4 1,3-Butadiene
3.4 Conclusions
References 4: Selective Bioethanol Conversion to Chemicals and Fuels via Advanced Catalytic Approaches
4.1 Introduction
4.2 Dehydration of Ethanol
4.2.1 Diethyl Ether Production
4.2.2 Ethylene Production
4.2.3 Propylene Production
4.3 Oxidation of Ethanol
4.3.1 Ethylene Oxide Production
4.3.2 Acetic Acid Production
4.4 Steam Reforming of Ethanol and Dehydrogenation
4.4.1 Steam Reforming of Ethanol to Hydrogen
4.4.2 Dehydrogenation of Ethanol
4.4.2.1 Acetaldehyde
4.4.2.2 Ethyl Acetate
4.5 Guerbet Reaction of Ethanol
4.6 Conclusions
References 5: A Spotlight on Butanol and Propanol as Next-Generation Synthetic Fuels
5.1 Introduction
5.2 Divergent Fuel Properties of Ethanol, Propanol, and Butanol
5.3 Petrochemical Routes for Butanol Production
5.4 Biological Route for Butanol Production
5.5 Petrochemical Routes for Propanol Production
5.6 Biological Routes for Propanol Production
5.7 Challenges and Future Perspectives
5.8 Conclusions
References
6: Technological Advancements in the Production and Application of Biomethanol
6.1 Introduction
6.2 Industrial Applications of Methanol

Summary: Toxic substances threatens aquatic and terrestrial ecosystems and ultimately human health. The book is a thoughtful effort in bringing forth the role of biotechnology for bioremediation and restoration of the ecosystems degraded by toxic and heavy metal pollution. The introductory chapters of the book deal with the understanding of the issues concerned with the pollution caused by toxic elements and heavy metals and their impacts on the different ecosystems followed by the techniques involved in monitoring of the pollution. These techniques include use of bio-indicators as well as modern techniques for the assessment and monitoring of toxicants in the environment. Detailed chapters discussing the role of microbial biota, aquatic plants, terrestrial plants to enhance the accumulation efficiency of these toxic and heavy metals are followed by remediation techniques involving myco-remediation, bio-pesticides, bio-fertilizers, phyto-remediation and rhizo-filtration. A sizable portion of the book has been dedicated to the advanced bio-remediation techniques which are finding their way from the laboratory to the field for revival of the degraded ecosystems. These involve bio-films, micro-algae, genetically modified plants and filter feeders. Furthermore, the book is a detailed comprehensive account for the treatment technologies from unsustainable to sustainable. We believe academicians, researchers and students will find this book informative as a complete reference for biotechnological intervention for sustainable treatment of pollution.

Contents:
Preface
Foreword
1. Concerns and Threats of Contamination on Aquatic Ecosystems
2. Effect of Pesticides on Fish Fauna: Threats, Challenges and Possible Remedies
3. Impact of Invasive Plants in Aquatic Ecosystems
4. Role of Modern Innovative Techniques for Assessing and Monitoring Environmental Pollution
5. Global Scenario of Remediation Techniques to Combat Environmental Pollution
6. Biopesticides: clean and viable technology for healthy environment
7. Inoculum addition in the presence of plant rhizosphere for petroleum polluted soil remediation
8. Vermicomposting: An Eco-friendly Approach for Recycling /Management of Organic Wastes
9. Bio-Fertilizers: Ecofriendly Approach for Plant and Soil Environment
10. Phytoremediation of heavy metals: an ecofriendly and sustainable approach
11. Credibility of in situ Phytoremediation for Restoration of Disturbed Environments
12. Role of White Willow (Salix alba L.) for Cleaning up the Toxic Metal Pollution
13. Mycoremediation: a Sustainable Tool for Abating Environmental Pollution
14. Microbial Biofilm Cell Systems for Remediation of Wastewaters
15. Pollution remediation by way of using genetically modified plants (GMP)
Index.

Summary: This book addresses the grave concerns stemming out due to conventional treatment techniques. The main focus of this book revolves round the central kernel of novel technology (bioremediation and biotechnology) which has emerged as an independent warrior to clean up and restore the disturbed environs. Furthermore, this book is a coherent assortment of diverse chapters relevant to the role of biotechnology and bioremediation for restoration of the ecosystems degraded by pesticide and heavy metal pollution. The inaugural chapters deal with the quantification of problem and its magnitude due to pesticides and heavy metals, followed by innovative modern biotechnological and bioremediation treatment technologies and sustainable techniques to remediate the persistent pollutants. It is a detailed comprehensive account for the treatment technologies from unsustainable to sustainable. Academicians, researchers and students shall find it as a complete wrap up regarding biotechnological intervention for sustainable treatment of pollution and shall suffice for the diverse needs of teaching and research.

Contents:
Preface
1. Causes and Effects of Pesticide and Metal Pollution on Different Ecosystems
2. Ecotoxicology of Heavy Metals: Sources, Effects and Toxicity
3. Role of Modern Innovative Techniques for Assessing and Monitoring Heavy Metal and Pesticide Pollution in Different Environments
4. Global Scenario of Remediation Techniques to Combat Pesticide Pollution
5. Mycoremediation: A Sustainable Approach for Pesticide Pollution Abatement
6. Bio-pesticides: Application and Possible Mechanism of Action
7. Values of Biofertilizers for Sustainable Management in Agricultural Industries
8.Role of Macrophytes in Spontaneous Lacustrine Phytofiltration
9. Phytoremediation of Heavy Metals Using Salix (Willows)
10. Photo catalysis: An Effective Tool for Treatment of Dyes Contaminated Wastewater
11. Removal of dyes from waste water by Micellar Enhanced Ultrafiltration
12. Biofilm: an innovative modern technology for aquatic pollution remediation
13. Heavy Metal Soil Contamination and Bioremediation
14. Environmental Biotechnology: For Sustainable Future
15. Global Environmental Regulations for Management of Pesticides
Index.

Summary: Plastic is one of the widely used polymers around the globe since its discovery. It is highly impossible to think the ease of life without the aid of plastic. Every year billion tons of plastic waste gets accumulated in the environment and leads to death of both marine and terrestrial animals. Plastic is very durable and needs around 1000 years to degrade under the natural environment. The present book illustrates the importance and significance of the bioremediation to tackle the problem of plastic waste. Previously, we have reported elite rhizobacterial isolates (Lysinibacillus fusiformis strain VASB14/WL and Bacillus cereus strain VASB1/TS) of Avicennia marina Vierh (Forsk.) from the West Coast of India with the potential to degrade plastic (polythene). The present book attempted to address the bioremediation scenario of plastic waste (including micro plastic) using microbes with bacteria in particular. Various strategies used to tackle with the plastic waste were highlighted with case studies of plastic waste management, including in vitro, in situ and ex situ with a special reference to biodegradation technology. After the biodegradation of the plastic using microbes, the generated plastic (polythene) degradation products (PE-DPs) were also documented using GC-MS technique followed by their deleterious effect on both animal and plant systems. The book also enhances the awareness of the plastic-free society and also suggests some alternative materials to be used instead of plastic. Lastly, the book suggests/recommends the strategies to be followed by the lawmakers in the government organizations/non-government organizations/social organizations to frame the regulations and guidelines to implement at mass level to reduce the generation of plastic waste.

Contents:
Module 1_Introduction
Module 2_Microplastic
Module 3_Plastic waste disposal and re-use of plastic waste
Module 4_Case studies and recent update of plastic waste degradation
module 5_Bacteria as key players of Plastic Bioremediation
Module 6_In situ remediation technology for plastic degradation
Module 7_Ex-situ remediation technology for plastic degradation
Module 8­_Social awareness of plastic waste threat
Module 9_Analysis of the plastic degradation products
Module 10_Toxicity testing of plastic degrading products
Module 11_Policy and legislation/regulations of plastic waste around the globe
Module 12_Conclusions and future needs.

Contents:
General introduction to biosensors and recognition receptors
Biomarkers in health care
The use of nanomaterials and microfluidics in medical diagnostics
SPR-based biosensor technologies in disease detection and diagnostics
Piezoelectric-based biosensor technologies in disease detection and diagnostics
Electrochemical-based biosensor technologies in disease detection and diagnostics
MEMS-based cell counting methods
Lab-on-a-chip platforms for disease detection and diagnosis
Applications of quantum dots in biosensors and diagnostics
Applications of molecularly imprinted nanostructures in biosensors and diagnostics
Smart nanomaterial's : applications in biosensors and diagnostics
Applications of magnetic nanomaterial's in biosensors and diagnostics
Graphene applications in biosensors and diagnostics
Optical biosensors and applications to drug discovery for cancer cases
Biosensors for detection of anticancer drug-DNA interactions.

Summary: This book reviews the application of nanosensors in food and agriculture. Nanotechnology has the potential to become transformative technology that will impact almost all sectors. Tools like nanosensors, which detect specific molecular interactions, can be used for on-site, in-situ and online measurements of various parameters in clinical diagnostics, environmental and food monitoring, and quality control. Due to their unprecedented performance and sensitivity, nanobiosensors are gaining importance in precision farming. The book examines the use of nanobiosensors in the monitoring of food additives, toxins and mycotoxins, microbial contamination, food allergens, nutritional constituents, pesticides, environmental parameters, plant diseases and genetically modified organisms. It also discusses the role of biosensors in increasing crop productivity in sustainable agriculture, and nanosensor-based smart delivery systems to optimize the use of natural resources such as water, nutrients and agrochemicals in precision farming.

Contents:
Recent trends, prospects, and challenges of nanobiosensors in agriculture
Nanostructured platforms integrated to biosensors: Recent applications in agriculture. Advances in nanotechnology for bio-sensing in agriculture and food
Nanomaterial based gas sensor for agriculture sector
Volatile organic compounds (VOCs) sensors for stress management in crops
Current trends of plasmonic nanosensors use in agriculture
Relevance of biosensor in climate smart organic agriculture and their role in environmental sustainability: What has been done and what we need to do?
New trends in biosensors for pesticide detection
Application of biosensor for the identification of various pathogens and pests mitigating against the agricultural production: recent advances
Gold nanoparticles-based point-of-care colorimetric diagnostic for plant diseases
Advancements in biosensors for fungal pathogen detection in plants
Journey of Agricultural sensors From conventional to ultra-modern
PART II: Biosensors in food science, Advances in biosensors based on electrospun micro/nanomaterials for food quality control and safety
Current trend of electrochemical sensing for mytoxins
Biosensor for fruit quality monitoring
Lateral flow assays for food authentication
Nanobiosensors in agriculture and foods: a scientometric review
PART III: Biosensors in animal and fishery Sciences, Biosensors: Modern tools for disease diagnosis and animal health monitoring
Nano-biosensing devices detecting biomarkers of communicable and non-communicable diseases of animals
Recent advances in biosensor development for poultry industry
Smart aquaculture: Integration of sensors, biosensors, and artificial intelligence
Biosensor as potential tool for on-site detection of insect pathogens.

Summary: "This book provides detailed review chapters on a range of nanostructures such as nanoparticles, nanowires, nanotubes, nanoribbons, nanorods, nanobelts and nanosheets in the construction of biosensors with set applications of biosensors nanotechnology for biological and chemical analyses, food safety industry, biomedical diagnostics, clinical detection, and environmental monitoring. The authors provide a comprehensive view of cutting-edge research on advanced materials for healthcare technology and applications. The book is written for scientists, researchers, and clinicians from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering"--Provided by publisher.

Contents:
1. Biosimilars for drug development : the time is now! / Bo Jin, Sandeep M. Menon, Kerry B. Barker, and Ralph B. D'Agostino
2. From isolation to integration : a systems biology approach for the discovery of therapeutic targets and biomarkers / Attila Seyhan and Claudio Carini
3. Immunogenicity of biological products : current perspectives and future implications / Candida Fratazzi, Attila Seyhan, and Claudio Carini
4. Interchangeability between biosimilar and innovator drug products / Bo Jin, Sandeep M. Menon, Kerry B. Barker, and Steven Ye Hua
5. Bridging a new biological product with its reference product / Jianfun (David) Li and Jin Xu
6. Accounting for covariate effect to show noninferiority in biosimilars / Siyan Xu, Kerry B. Barker, Sandeep M. Menon, and Ralph B. D'Agostino
7. Novel method in inference of equivalence in biosimilars / Siyan Xu, Steven Ye Hua, Ronald Menton, Kerry B. Barker, Sandeep M. Menon, and Ralph B. D'Agostino
8. Multiplicity adjustments in testing for bioequivalence / Steven Ye Hua, Siyan Xu, and Ralph B. D'Agostino
9. Bayesian methods to assess bioequivalence and biosimilarity with case studies / Steven Ye Hua, Siyan Xu, Kerry B. Barker, Shan Mei Liao, and Shujie Li
10. Average inferiority measure and standardized margins to address the issues in biosimilar trials / Gang Li and Weichung Joe Shih
11. Bayesian methods for design and analysis of noninferiority trials / Mani Lakshminarayanan and Fanni Natanegara.

Contents:
The history of therapeutic monoclonal antibodies / Regis Sodoyer
Structure, classification and naming of therapeutic monoclonal antibodies / Zhinan Xia
Mechanism of action for therapeutic antibodies / Yu Zhou and James D. Marks
Therapeutic monoclonal antibodies and their targets / Maurizio Chiriva-Internati, et al
Antibody post-translational modifications / Roy Jefferis
The pharmacology, pharmacokinetics, and pharmacodynamics of antibodies / Ningning Xu, Meimei Liu, Margaret Liu
Monoclonal antibodies : applications in clinical oncology / Jeanene ("Gigi") Robison
Development of biosimilar rituximab and clinical experience / Reena Nair
Monoclonal antibodies for infectious diseases / Steven J. Projan
Monoclonal antibodies for musculoskeletal, CNS, and other diseases / Junming Yie and Tao Wu
Manufacture of recombinant therapeutic proteins using chinese hamster ovary cells in large-scale bioreactors : history, methods and perspectives / Florian M. Wurm and Maria De Jesus
Process development / Samuel D. Stimple and David W. Wood
Biosimilars and biobetters : impact on biopharmaceutical manufacturing and CMOs / Ronald A. Rader
Cell line and cell culture development for biosimilar antibody drug manufacturing / Jianguo Yang
Product analysis of biosimilar antibodies / Weidong Jiang, Scott Liu and Ziyang Zhong
Bioanalytical development / Rafiq Islam
Preclinical and clinical development of biosimilar antibodies / João Eurico Fonseca and João Gonçalves
Regulatory issues / Clarinda Islam
Legal considerations / K. Lance Anderson, Jennifer R. Moore Meline, and Jonathan D. Ball
ADCC enhancement technologies for next generation therapeutic antibodies / Cheng Liu and Su Yan
Biosimilar antibody half-life : engineering for optimal performance / K. John Morrow, Jr
Technologies for antibody drug conjugation / Patrick G. Holder and David Rabuka.

Contents:
1. Biosonar of Bats and Toothed Whales: An Overview / Annemarie Surlykke and Paul E. Nachtigall
2. Sonar Signals of Bats and Toothed Whales / Brock (M. B.) Fenton, Frants H. Jensen, Elisabeth K. V. Kalko, and Peter L. Tyack
3. Production of Biosonar Signals: Structure and Form / Whitlow W. L. Au and Roderick A. Suthers
4. Sound Intensities of Biosonar Signals from Bats and Toothed Whales / Magnus Wahlberg and Annemarie Surlykke
5. Hearing During Echolocation in Whales and Bats / Paul E. Nachtigall and Gerd Schuller
6. Localization and Classification of Targets by Echolocating Bats and Dolphins / James A. Simmons, Dorian Houser, and Laura Kloepper
7. On-Animal Methods for Studying Echolocation in Free-Ranging Animals / Mark Johnson
8. Analysis of Natural Scenes by Echolocation in Bats and Dolphins / Cynthia F. Moss, Chen Chiu, and Patrick W. Moore
9. Echolocation in Air and Water / Peter Teglberg Madsen and Annemarie Surlykke.

Summary: "New for 2014, Biostatistics: The Bare Essentials, 4th Edition, includes updated information on robust estimators of the mean, the problems of multiple hypothesis testing, bootstrapping and resampling and non-parametric stats. In addition, an entirely new chapter title Measures of Impact discusses measures of incidence and prevalence, risk, morbidity and fatality rates, and more."

Contents:
The nature of data and statistics: the basics
Looking at the data
Describing the data with numbers
The normal distribution
Probability
Elements of Statistical inference
Analysis of variance: Comparing two groups the T-test
More than two groups one way ANOVA
Factorial ANOVA
Two repeated observations the paired T-test and alternatives
Repaeted-measures ANOVA
Multivariate ANOVA (MANOVA)
C.R.A.P. detectors
Regression and correlation: Simple regression and correlation
Multiple regression
Logistic and poisson regression
Advanced topis in regression and ANOVA
Measuring change
Analysis of Longitudinal data: Hierarchical linear modeling
Non-parametric statistics: Tests of significance for categorical frequency data
Measures of association for categorical data
tests of significance for ranked data
Measures of association for ranked data
Survival analysis
Measures of impact introductory side bar
Reprise: Equivalence and Non-inferiority testing
Screwups, oddballs, and other vagaries of science
Putting it all together
gettting started with SPSS.

Contents:
1. Language elements
2. Simple descriptive statistics
3. Measures of association, comparison of means or proportions
4. Correlation, linear regression
5. Logistic regression
6. Survival curves, cox regression
Appendix A. Introduction to SAS studio
Appendix B. Introduction to SAS Macro
Appendix C. Introduction to SAS IML.

Summary: "Biostatistics for Human Genetic Epidemiology provides statistical methodologies and R recipes for human genetic epidemiologic problems. It begins by introducing all the necessary probabilistic and statistical foundations, before moving on to topics related human genetic epidemiology, with R codes illustrations for various examples. This clear and concise book covers human genetic epidemiology, using R in data analysis, including multivariate data analysis. It examines probabilistic and statistical theories for modeling human genetic epidemiology – leading the readers through an effective epidemiologic model, from simple to advanced levels. Classical mathematical, probabilistic, and statistical theory are thoroughly discussed and presented. This book also presents R as a calculator and using R in data analysis. Additionally, it covers Advanced Human Genetic Data Concepts, the Study of Human Genetic Variation, Manhattan Plots, as well as the Procedures for Multiple Comparison. Numerous Worked Examples are provided for illustrations of concepts and real-life applications"--Publisher's description.

Contents:
Introduction to human genetic epidemiology / Bertram K. C. Chan
Data analysis using R programming / Bertram K. C. Chan
Applied statistics for human genetics using R / Bertram K. C. Chan
Applied human genetic epidemiology / Bertram K. C. Chan
Human genetic epidemiology using R.

Summary: This book discusses the natural classification and biosystematics of Triticeae, and presents the most significant findings of comprehensive studies on the Triticeae, an important tribe in the grass family (Poaceae) that includes major crops such as wheat, barley, rye and triticale, as well as various forage crops found in different genera. The five-volume Chinese version of Biosystematics of Triticeae was published in 1998, 2004, 2006, 2011, and 2013, and included the 30 genera, 2 subgenera, 464 species, 9 subspecies, and 186 varieties of Triticeae identified to date. This completely revised English edition features up-to-date international research and the latest advances in the field. The book is divided into five volumes, covering a wide range of disciplines from traditional taxonomy and cytogenetics, to molecular phylogeny. Volume I, Triticum-Aegilops complex focuses on the taxonomy and generic relationships of Triticum and Aegilops, discussing the origin of common wheat as a crop. Volume II highlights the taxonomy and systematics of Secale, Tritiosecale, Pseudosecale, Eremopyrum, Henrardia, Taeniantherum, Heteranthelium, Crithopsis, and Hordeum. Volume III describes perennial genera and species including Kengyilia, Douglasdeweya, Agropyron, Australopyrum, and Anthosachne. Volume IV addresses perennial genera and species including Stenostachys, Psathyrostachys, Leymus, Pseudoroegneria, and Roegeneria. Volume V presents perennial genera and species such as Campeiostachys, Elymus,Pascopyrum, Lophopyrum, Trichopyrum, Hordelymus, Festucopsis, Peridictyon, and Psammopyrum.

Contents:
Chapter 1. Classical morphological taxonomy
Chapter 2. Systematical survey of the genus Aegilops
Chapter 3. Discovery of wild Triticum species
Chapter 4. Reihe system of genus Triticum
Chapter 5. Triticum taxon of British School and Soviet School in the 20 century
Chapter 6. Cytogenetic relationship of Triticum and Aegilops species
Chapter 7. Development of Triticum taxonomy
Chapter 8. Taxonomy of the genus Triticum
Chapter 9. Taxon within a Triticum species
Chapter 10. Geographic and historical origin of wheat
Chapter 11. Artificially synthesized species and genera.

Summary: Plants have always occupied a prominent position in the life of every living being. Plants are the primary source of food, shelter and medicines. The global inclination toward herbal medicine has advanced the expansion of plant-based pharmaceutical industries to a vast extent. The production of traditional medicine at global market has been estimated to touch US trillion by 2050. Some of the useful plant-based drugs include vinblastine, vincristine, taxol, podophyllotoxin, camptothecin, digoxigenin, morphine, codeine, aspirin, atropine, capscicine, allicin, curcumin, artemesinin and ephedrine. Genus Sapindus is an important economical and medicinal trees, distributed over the world. Soap nuts contain higher amount of saponin, a natural detergent which can be used to clean clothes and hairs. Sapindus species possesses various pharmacological properties including antimicrobial, antioxidant, anti-inflammatory, anticancer, hepatoprotective, anti-trichomonas activity. Extracts of this plant are rich in various phytochemicals and polyphenolic compounds. All the pharmacological properties are due to presence of saponins. Biotechnological techniques can improve the saponin content; thus this chemical content can be produced at large scale and can be used as phytomedicine. We hope that this book would be of great use to under graduates, postgraduates, scientists, researchers and faculty members who are studying, teaching or working in the field of Biotechnology, Phytochemistry and Ethnopharmacology. The techniques explained in this book could be of immense use for the researchers working in this area. We shall deeply appreciate receiving any critical comments and suggestions from the readers from the different parts of globe which would help us improve the first edition of this publication.

Contents:
Intro; Preface; Contents; About the Authors; Abbreviations/Acronyms; List of Figures; List of Tables;
1: Introduction; Further Readings;
2: Morphological Characteristics of Sapindus Species; 2.1 Botanical Classification of Sapindus; 2.2 Sapindus mukorossi; 2.3 Sapindus trifoliatus; 2.4 Sapindus saponaria; 2.5 Sapindus rarak; 2.6 Traditional Uses of Sapindus Species; Further Readings;
3: Traditional Uses and Ethnomedicinal Values of Sapindus spp.; 3.1 History of Traditional Medicine; 3.2 Resources of Medicinal Materials; 3.3 Current Status at National and International Levels 3.4 Validation of Traditional Medicinal Values Through Scientific Experiments3.5 Herbal Shampoo Preparation; 3.6 Traditional Medicinal Uses of Sapindus spp.; Further Readings;
4: Biotechnological Advances in Sapindus sps.; 4.1 Introduction of Biotechnology; 4.2 In Vitro Regeneration of Woody Trees; 4.3 Regeneration via Organogenesis; 4.4 Regeneration via Somatic Embryogenesis; 4.5 Advantages and Limitations of Micropropagation Techniques; 4.6 Propagation of Sapindus Species; 4.6.1 Conventional Propagation of Sapindus; 4.6.2 Micropropagation Studies; 4.7 Mass Propagation of Sapindus mukorossi 4.7.1 Organogenesis4.7.2 Somatic Embryogenesis; 4.7.2.1 Seedling-Derived Leaf Explants; 4.7.2.2 In Vivo Leaf Explants; 4.7.2.3 Rachis Explants; 4.7.2.4 In Vitro Leaf Explants; 4.8 In Vitro Regeneration in Sapindus trifoliatus; 4.8.1 Organogenesis; 4.8.2 Somatic Embryogenesis; 4.8.2.1 Leaf Explant; 4.8.2.2 Development of Somatic Embryos in Saline Media; 4.8.2.3 Sepal Explant; 4.9 Genetic Fidelity Appraisal; 4.9.1 Genetic Fidelity in Sapindus mukorossi; 4.9.1.1 In Vitro Raised Plantlets from Leaf Explants; 4.9.1.2 In Vitro Raised Plantlets from Rachis Explants 4.9.1.3 In Vitro Raised Plantlets from Leaf Explants4.9.2 Genetic Fidelity in Sapindus trifoliatus; 4.10 Solubilizing Property; 4.11 Biodiesel Production; Further Readings;
5: Phytochemical Analysis and Pharmaceutical Development from Sapindus spp.; 5.1 Phytochemistry of Sapindus; 5.2 Phytochemistry of S. trifoliatus, S. saponaria and S. rarak; 5.3 Saponins; 5.3.1 Biosynthesis of Saponins; 5.3.2 Development of Sapogenin Diversity; 5.4 Evaluation of Phytochemical Activity from S. mukorossi; 5.4.1 Experimental Setup; 5.4.1.1 Material Collection and Preparation of Extracts 5.4.1.2 Preparation of Stock Sample of Extracts5.4.1.3 Antioxidant Activity; 5.4.1.4 Estimation of Reducing Potential; 5.4.1.5 Thiobarbituric Acid Reactive Substance (TBARS) Assay; 5.4.1.6 Hydrogen Peroxide (H2O2) Scavenging Assay; 5.4.1.7 Estimation of Total Phenolic Content; 5.4.1.8 Estimation of Total Flavonoid Content; 5.5 Observations; 5.5.1 Antioxidant Activity Through TLC and DPPH Assay; 5.5.2 [beta]-Carotene/Linoleic Antioxidant Assay; 5.5.3 Hydrogen Peroxide Scavenging Activity; 5.5.4 Reducing Potential from Leaf and Fruitś Extracts

Summary: This book compiles selected articles presented at the International Conference on Biotechnology & Biological Sciences, BIOSPECTRUM 2017, organized by the Department of Biotechnology, University of Engineering & Management, Kolkata. Focusing on biotechnology-based analysis and intervention to address certain human diseases, the book includes a holistic discourse on disease profiling, molecular level analysis of diseases, and non-invasive medical interventions. It features articles on non-invasive treatment of iron deficiency anemia with iron nanoparticles; novel diagnosis methods based on microarray data; analysis using machine learning techniques like artificial neural network for early detection and treatment of cancer; and drug discovery for preventing the growth of human leukemic cells. Further, the book sheds light on in silico drug design using lipopeptides, and identifying the binding sites for their corresponding ligands. Presenting the concepts of the design of potent and safe antimicrobial compounds to fight multi drug resistant pathogens, it also includes interesting reviews on the design and development of various non-invasive methods, such as multi NIR wavelength probes to identify the risk areas in the diabetic foot at an early stage; and a low-cost cochlear implant prototype designed and developed from commercial off the-shelf components to empower the hearing impaired. The book appeals to students, academics and researchers in a wide range of subject areas, including biotechnology, life sciences, medicine and cancer research.

Contents:
Foreword
Chapter 1: Design of Multi-wavelength Near Infra-Red probe to detect risk areas in diabetic foot
Chapter 2: Cellular and molecular response for sensitising cancer cells and protecting the normal cells from radiation-induced damages
Chapter 3: A Novel Approach for Production and Study of Medical Ultrasound from Low Cost Electromagnetic Transducers
Chapter 4: Altered profile of regulatory T cells and NKT cells are characteristics of Chikungunya associated polyarthralgia
Chapter 5: Cytotoxicity and Apoptosis of Human Colon Carcinoma Cell (HT 29 Cells), Treated with Methanolic Extract of Chlorococcum humicola
Chapter 6: Universal primer design for the detection of diverged CTX-M Beta Lactamases (ESBL) that give penicillin and cephalosporin resistance during superbug infections
Chapter 7: Lipopeptides as therapeutics: Molecular docking and drug design
Chapter 8: Design and Simulation of Geometrical Shape and Size Variations of Micro-electrode for Cochlear Implant
Chapter 9: Molecular and Protein Interaction Studies for Inhibiting Growth of Human Leukemic Cells: An In silico Structural Approach to Instigate Drug Discovery
Chapter 10
Laccase Mediated Synthesis of Bio-material using Agro-residues
Chapter 11: Extraction of Fungal Xylanase using ATPS-PEG/sulphate and its Application in Hydrolysis of Agricultural Residues
Chapter 12: Thyme (Thymus vulgaris) essential oil based antimicrobial nanoemulsion formulation for fruit juice preservation.

Summary: This book offers an overview of the diverse fields application of proteases (also termed proteolytic enzymes or proteinases), including food science and technology, pharmaceutical industries, and detergent manufacturing, reviewing the advances in the biotechnological application plant proteolytic enzymes over the last decade. In recent years, they have been the focus of renewed attention from the pharmaceutical and biotechnology industries, not only because of their activity on a wide variety of proteins but also because they are active over a range of temperatures and pHs. The main audience of this book are researchers working with plant proteases but also professionals from several industry segments such as food production and pharmaceutical companies.

Contents:
An overview of plant proteolytic enzymes
Milk-clotting plant proteases for cheesemaking
Use of plant proteolytic enzymes for meat processing
Peptide synthesis using proteases as catalyst
Plant proteolytic enzymes: their role as natural pharmacophores
Potential use of plant proteolytic enzymes in hemostasis.

Summary: This book presents the latest research on the uses of polyhydroxyalkanoates (PHA), introducing readers to these natural, biodegradable polyesters produced by microorganisms, their functions and applications. The individual chapters discuss the various potentials of these bioplastics, which offer an attractive alternative to non-biodegradable plastics. The book also describes the diverse medical and biomedical applications of PHAs, including their use as drug carriers, memory enhancers, and biocontrol agents, and examines their role in creating a more sustainable economy which is the need of the hour.

Contents:
Intro; Dedication; Preface; Contents; About the Editor;
1: The Dawn of Novel Biotechnological Applications of Polyhydroxyalkanoates; 1.1 Introduction; 1.2 Antimicrobials, Biocontrol and Anticancer Agents; 1.3 Drug Carriers; 1.4 Engineering Tissues; 1.5 Medical Implants and Devices; 1.6 Anti-osteoporosis Agent; 1.7 Memory Enhancer; 1.8 Packaging; 1.9 Agriculture; 1.10 Challenges in Customizing PHAs; 1.11 The Future; References;
2: Strategy for Biosynthesis of Polyhydroxyalkonates Polymers/Copolymers and Their Application in Drug Delivery; 2.1 Introduction 2.2 Strategy for Biosynthesis of Polyhydroxyalkonates2.2.1 Enhancement of PHA Accumulation and Production; 2.2.2 Approaches to Produce Copolymers; 2.2.2.1 Precursor Feeding; 2.2.2.2 Metabolic Engineering to Synthesize Copolymer Precursors; 2.3 Biodegradability and Biocompatibility of PHA; 2.4 PHA in Drug Delivery; 2.4.1 Intrinsic PHA in Drug Delivery; 2.4.1.1 Nanoparticles; 2.4.1.2 Microsphere; 2.4.1.3 Scaffolds; 2.4.1.4 Nanofibers; 2.4.2 Functionalized PHA in Drug Delivery; 2.4.2.1 Functionalization of PHA Granule Associated Proteins; 2.4.2.2 Functionalized PHA Graft Polymer 2.4.2.3 Functionalized PHA Block Copolymer2.5 Route for Drug Delivery; 2.5.1 Oral Route; 2.5.2 Intravenous Route; 2.5.3 Subcutaneous Route; 2.6 Drug Release Mechanism; 2.7 Factors Affect Drug Release; 2.8 Conclusion; 2.9 Opinion; References;
3: Applications of Polyhydroxyalkanoates and Their Metabolites as Drug Carriers; 3.1 Introduction; 3.2 Applications of PHA as Drug Carriers; 3.3 Anticancer Carriers; 3.4 Antibacterial Carriers; 3.5 Wound Dressers; 3.6 Conclusion; References;
4: Polyhydroxyalkanoates Applications in Antimicrobial Agents Delivery and Wound Healing 4.1 Introduction4.2 Bacterial Infections; 4.3 PHAs as Antimicrobial Agents; 4.4 PHAs as Delivery System of Antimicrobial Agents; 4.4.1 PHB; 4.4.2 PHAs, Their Derivatives and Copolymers; 4.5 Antibacterial Activity Against Biofilms; 4.6 PHAs Applications; 4.6.1 PHAs as Delivery Systems for Oral Use; 4.6.2 PHAs in Wound Healing; 4.6.3 PHAs as Bacteriostatic Agents in Animal Production; 4.7 Conclusions: Opinion; References;
5: Polyhydroxyalkanoates Applications in Drug Carriers; 5.1 Introduction; 5.2 Anticancer; 5.3 PHB Microspheres; 5.4 Encapsulation; 5.4.1 Synthesis of Capsules 5.4.2 Characterization Techniques for PHA Capsules5.4.3 Factors Affecting PHA Capsules Properties; 5.4.4 Properties of PHA Capsules; 5.5 Pharmacokinetics and Biodegradation of PHAs; 5.6 Bio-distribution and Toxicity Studies in Animals; 5.7 Nanoparticles; 5.8 Hydrogels; 5.9 Non-woven Membrane; 5.10 Micelles; 5.11 Bone Repair; 5.12 Anti-proliferative Activity; 5.13 Hemolytic Properties; 5.14 Conclusions; 5.15 Opinion; References;
6: Applications of Polyhydroxyalkanoates Based Nanovehicles as Drug Carriers; 6.1 Introduction; 6.2 Structure of PHA; 6.3 Bacterial PHA

Summary: This book discusses the practical applications of quorum sensing inhibitors for both human and plant health. Quorum sensing inhibitors that disrupt microbial biofilms can be employed to treat bacterial infections. The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors. Quorum sensing is the mechanism through which bacteria develop antibiotic resistance. Intended to provide a clearer understanding of the practical applications of quorum sensing inhibitors, the book details how the problem of antibiotic resistance can be countered through the intelligent application of quorum sensing inhibitors.

Contents:
A. Human Health
Inhibition of Quorum-sensing: a new paradigm in controlling bacterial virulence and biofilm formation
Targeting Quorum Sensing Mediated Staphylococcus aureus Biofilms: A Proteolytic Approach
Alternative strategies for control of quorum sensing and biofilm formation of pathogenic Pseudomonas aeruginosa by plant, marine and synthetic based quorum sensing inhibitors
Quorum Quenching and Biofilm Inhibition: Alternative imminent strategies to control the disease Cholera
Anti-biofilm peptides: A new class of quorum quenchers and their prospective therapeutic applications
Quorum sensing inhibition: A target for treating chronic wounds
Efflux pump-mediated quorum sensing--new avenues for modulation of antimicrobial resistance and bacterial virulence
CRISPR-Cas systems regulate quorum sensing genes and alter virulence in bacteria
Developing Anti-virulence Chemotherapies by Exploiting the Diversity of Microbial Quorum Sensing Systems
Synergism between quorum sensing inhibitors and antibiotics: Combating the antibiotic resistance crisis
Nanoparticles as quorum sensing inhibitor: Prospects and limitations
Nanotechnological Approaches in Quorum sensing Inhibition
Bacterial-mediated biofouling: Fundamentals and control techniques
Technological developments in quorum sensing and its inhibition for medical applications
Combating Staphylococcal Infections Through Quorum Sensing Inhibitors. B. Plant Health
Marine biodiversity as a resource for bioactive molecules as inhibitors of microbial quorum sensing phenotypes
Quorum Sensing in plant pathogenic bacteria and its relevance in plant health
Scope of pathogenesis-related proteins produced by plants in interrupting quorum sensing signaling
Bioactive phytochemicals targeting microbial activities mediated by quorum sensing
Quorum sensing interference by natural products from medicinal plants: Significance in combating bacterial infection
Enzymatic Quorum Quenching for Virulence Attenuation of Phytopathogenic Bacteria.

Summary: For the majority of the world's population, medicinal and aromatic plants are the most important source of life-saving drugs. Biotechnological tools represent important resources for selecting, multiplying and conserving the critical genotypes of medicinal plants. In this regard, in-vitro regeneration holds tremendous potential for the production of high-quality plant-based medicines, while cryopreservation - a long-term conservation method using liquid nitrogen - provides an opportunity to conserve endangered medicinal and aromatic plants. In-vitro production of secondary metabolites in plant cell suspension cultures has been reported for various medicinal plants, and bioreactors represent a key step toward the commercial production of secondary metabolites by means of plant biotechnology. Addressing these key aspects, the book contains 29 chapters, divided into three sections. Section 1: In-vitro production of secondary metabolites Section 2: In-vitro propagation, genetic transformation and germplasm conservation Section 3: Conventional and molecular approaches.

Contents:
Intro; Preface; Contents; About the Editor; Part I: In Vitro Production of Secondary Metabolite;
Chapter 1: Production ofPlant Secondary Metabolites: Current Status andFuture Prospects; 1.1 Introduction; 1.1.1 Plant Secondary Metabolites; 1.1.2 Terpenes; 1.1.3 Phenolic Compounds; 1.1.4 Nitrogen-Containing Compounds; 1.2 Production ofPlant Secondary Metabolites; 1.2.1 Callus Culture; 1.2.2 Hairy Root Culture; 1.2.3 Organ Culture; 1.2.4 Elicitation; 1.2.5 Endophytes; 1.2.6 Nitric Oxide; 1.2.7 Abiotic Stress; 1.2.8 Bioreactor; 1.2.9 Metabolic Engineering; 1.2.10 Immobilization 1.3 Production ofValuable Pharmaceutical Compounds ThroughIn Vitro Culture Techniques1.3.1 Taxol; 1.3.2 Morphine andCodeine; 1.3.3 Ginsenosides; 1.3.4 L-DOPA; 1.3.5 Diosgenin; 1.3.6 Capsaicin; 1.3.7 Berberine; 1.3.8 Camptothecin; 1.3.9 Vincristine andVinblastine; 1.4 Conclusions; References;
Chapter 2: The Effects ofrol Genes ofAgrobacterium rhizogenes onMorphogenesis andSecondary Metabolite Accumulation inMedicinal Plants; 2.1 Introduction; 2.2 Effect ofrolA Gene onMorphogenesis; 2.3 Effect ofrolB Gene onMorphogenesis; 2.4 Effect ofrolC Gene onMorphogenesis 2.5 Effect ofrolD Gene onMorphogenesis2.6 Effect ofrolABC Gene onMorphogenesis; 2.7 The 'rol Effect' onSecondary Metabolites inPlants; 2.8 Effect ofrolA Gene onPlant Secondary Metabolite Accumulation; 2.9 Effect ofrolB Gene onPlant Secondary Metabolite Accumulation; 2.10 Effect ofrolC Gene onPlant Secondary Metabolite Accumulation; 2.11 Synergistic Effect ofrol ABC Gene onPlant Secondary Metabolite Accumulation; 2.12 Conclusion; References;
Chapter 3: Conventional andBiotechnological Approaches toEnhance Steviol Glycosides (SGs) inStevia rebaudiana Bertoni; 3.1 Introduction 3.2 Conventional Approaches3.2.1 Enhancement by Physical Factors; 3.2.2 Enhancement by Chemical Factors; 3.3 Biotechnological Interventions; 3.3.1 Micropropagation; 3.3.2 Enhancement by Biological Factors; 3.3.3 Hairy Root Culture andMetabolic Engineering; 3.4 Conclusion; References;
Chapter 4: Effect ofChemical Elicitors onPentacyclic Triterpenoid Production inInVitro Cultures ofAchyranthes aspera L.; 4.1 Introduction; 4.1.1 Taxonomy ofthePlant; 4.1.2 Ethnobotanical Significance; 4.1.3 Pharmacology; 4.1.4 Chemical Properties; 4.2 Methodology; 4.2.1 Sampling andCollection 4.2.2 Sample Authentication4.2.3 Sample Processing; 4.2.4 Effect ofPlant Growth Regulators onShoot Induction andRate ofMultiplication; 4.2.5 Effect ofElicitors withandWithout PGRs forProduction ofTriterpenoids; 4.2.6 Culturing Conditions; 4.2.7 Extraction; 4.2.8 RP-UFLC Analysis ofSelected Triterpenoids; 4.3 Results andDiscussion; 4.3.1 RP-UFLC Analysis ofSelected Triterpenoids; 4.3.2 Use ofSalicylic Acid (SA), Methyl Jasmonate (MeJA), Jasmonic Acid (JA), andChitosan (CH) inMedia Fortified withandWithout PGRs forProduction ofTriterpenoids

Summary: This book presents a comprehensive collection of various in situ and ex-situ soil remediation regimes that employ natural or genetically modified microbes, plants, and animals for the biodegradation of toxic compounds or hazardous waste into simpler non-toxic products. These techniques are demonstrated to be functionally effective in connection with physical, chemical, and biological strategies. Soil and water contamination through heavy metals, hydrocarbons and radioactive wastes is of global concern, as these factors have cumulative effects on the environment and human health through food-chain contamination. The book discusses the utilization of algae, plants, plant-associated bacteria, fungi (endophytic or rhizospheric) and certain lower animals for the sustainable bioremediation of organic and inorganic pollutants. In addition, it explores a number of more recent techniques like biochar and biofilms for carbon sequestration, soil conditioning and remediation, and water remediation. It highlights a number of recent advances in nanobioremediation, an emerging technology based on biosynthetic nanoparticles. Lastly, it presents illustrative case studies and highlights the successful treatment of polluted soils by means of these strategies.

Contents:
Intro; Preface; Contents; About the Authors; Abbreviations;
Chapter 1: Soil Pollution: Causes and Consequences; 1.1 Introduction; 1.2 Causes of Soil Pollution; 1.2.1 Natural Sources; 1.2.1.1 Volcanic Eruptions; 1.2.1.2 Earthquakes; 1.2.1.3 Alterations in Rainfall Patterns; 1.2.1.4 Geographical Changes; 1.2.1.5 Tsunamis; 1.2.2 Anthropogenic Sources; 1.2.2.1 Solid Wastes; Municipal Solid Wastes (MSW); Hospital Wastes; Industrial Wastes; 1.2.2.2 Agricultural Practices; Herbicides; Insecticides; Fungicides; 1.2.2.3 Radioactive Wastes; 1.2.2.4 Chemical Wastes; 1.2.2.5 Mining and Smelting. 1.3 Harmful Effects of Soil Pollution1.4 Remedies to Cope with Soil Pollution; 1.5 Conclusions; References;
Chapter 2: Ex situ Soil Remediation Strategies; 2.1 Introduction; 2.2 Land Farming; 2.3 Biopile; 2.4 Windrow; 2.5 Composting; 2.6 Soil Washing; 2.7 Bioreactor; 2.8 Absorption/Adsorption; 2.9 Ion Exchange; 2.10 Pyrolysis; 2.11 Ultrasonic Technology; 2.12 Conclusions; References;
Chapter 3: In Situ Soil Remediation Strategies; 3.1 Introduction; 3.2 Physical Methods of Soil Remediation; 3.2.1 Physical Separation; 3.2.2 Soil Flushing; 3.2.3 Volatilization; 3.2.4 Froth Flotation. 3.2.5 Thermal Remediation3.2.5.1 Electrical Resistance Heating (ERH); 3.2.5.2 Steam Injection and Extraction; 3.2.5.3 Conductive Heating; 3.2.5.4 Radio-Frequency Heating (RFH); 3.2.5.5 In situ Vitrification (ISV); 3.3 Conclusions; References;
Chapter 4: Chemical Methods of Soil Remediation; 4.1 Introduction; 4.2 Chemical Leaching; 4.3 Chemical Fixation; 4.4 Chemical Oxidation; 4.5 Electrokinetic Remediation; 4.6 Conclusions; References;
Chapter 5: Biochar and Soil Remediation; 5.1 Introduction; 5.2 Carbon Sequestration; 5.3 Nutrient Exchange; 5.4 Water Holding; 5.5 Adsorption/Absorption. 5.6 Oxidation/Reduction5.7 Biochar-Microbe Interaction in Soil; 5.8 Remediation of Organic and Inorganic Contaminants from Soils; 5.9 Conclusions; References;
Chapter 6: Soil Remediation Through Microbes; 6.1 Introduction; 6.2 Microbial Degradation of Petroleum Hydrocarbons; 6.3 Bioventing; 6.4 Bioleaching; 6.5 Bioaugmentation; 6.6 Mycoremediation; 6.7 Conclusions; References;
Chapter 7: Soil Remediation Through Algae, Plants and Animals; 7.1 Introduction; 7.2 Phycoremediation; 7.3 Phytoremediation; 7.3.1 Rhizofiltration; 7.3.2 Phytotransformation; 7.3.2.1 Degradation; 7.3.2.2 Volatilization. 7.3.2.3 Stabilization7.3.3 Phytoextraction/Phytoaccumulation; 7.3.4 Phytomining; 7.3.5 Phytostimulation; 7.4 Genetic Engineering Approaches for Phytoremediation; 7.5 Animal-Mediated Soil Remediation; 7.6 Conclusions; References;
Chapter 8: Nanobioremediation; 8.1 Introduction; 8.2 Properties of Nanoparticles; 8.3 Types of Nanoparticles; 8.3.1 TiO2 (Titanium Dioxide) Based Nanoparticles; 8.3.2 Iron Based Nanoparticles; 8.3.3 Bimetallic Nanoparticles; 8.3.4 Nanoclays; 8.3.5 Nanotubes; 8.3.6 Dendrimers and Nanosponges; 8.3.7 Magnetic Nanoparticles.

Summary: During the past 15 years, cellular and molecular approaches have emerged as valuable adjuncts to supplement and complement conventional breeding methods for a wide variety of crop plants. Biotechnology increasingly plays a role in the creation, conservation, characterization and utilization of genetic variability for germplasm enhancement. For instance, anther/microspore culture, somaclonal variation, embryo culture and somatic hybridization are being exploited for obtaining incremental improvement in the existing cultivars. In addition, genes that confer insect- and disease-resistance, abiotic stress tolerance, herbicide tolerance and quality traits have been isolated and re-introduced into otherwise sensitive or susceptible species by a variety of transgenic techniques. Together these transformative methodologies grant access to a greater repertoire of genetic diversity as the gene(s) may come from viruses, bacteria, fungi, insects, animals, human beings, unrelated plants or even be artificially derived. Remarkable achievements have been made in the production, characterization, field evaluation and commercialization of transgenic crop varieties worldwide. Likewise, significant advances have been made towards increasing crop yields, improving nutritional quality, enabling crops to be raised under adverse conditions and developing resistance to pests and diseases for sustaining global food and nutritional security. The overarching purpose of this 3-volume work is to summarize the history of crop improvement from a technological perspective but to do so with a forward outlook on further advancement and adaptability to a changing world. Our carefully chosen "case studies of important plant crops" intend to serve a diverse spectrum of audience looking for the right tools to tackle complicated local and global issues.

Contents:
Intro; Dedication; Foreword; Preface; Contents; Contributors; About the Editors; Cell andTissue Culture Approaches inRelation toCrop Improvement; 1 Introduction; 2 Micropropagation; 2.1 Significance ofMicropropagation; 3 Meristem Culture; 4 Micrografting; 5 Somatic Embryogenesis; 6 Somaclonal Variation; 6.1 Induction ofSomaclonal Variation; 6.2 Causes ofSomaclonal Variation; 6.2.1 Chromosomal Changes; 6.2.2 Mitotic Crossing Over; 6.2.3 Apparent 'Point' Mutations; 6.2.4 Cytoplasmic Genetic Changes; 6.2.5 Amplifications andDeamplifications; 6.2.6 Transposable Element Activation. 2.4.1 Establishment ofAseptic Cultures ofExplants InVitro (Stage 1)Collection ofTops andExcision ofSpindles; Sterilization ofSpindles andPreparation ofExplants; Inoculation andIncubation ofSpindle Leaf Segments; 2.4.2 Shoot Multiplication (Stage 2); 2.4.3 Induction ofRoots andHardening ofPlantlets InVitro (Stage 3); 2.4.4 Transfer ofPlantlets toSoil (Stage 4); 2.5 Transplanting ofMicropropagated Plants intheField; 2.6 Production ofCommercial Seed; 2.7 Precautions toBeTaken During Micropropagation; 2.8 Scenario ofSugarcane Micropropagation. 2.9 Significance ofMicropropagation2.10 Problems Associated withMicropropagation; 3 Somatic Embryogenesis; 3.1 Regulation ofSomatic Embryogenesis; 3.2 Effect ofSource ofExplant onSomatic Embryogenesis; 3.3 Evidence forSomatic Embryogenesis andProteins Produced fromCallus; 3.4 Somatic Embryogenesis fromCell Suspension Cultures; 3.5 Somatic Embryogenesis andCryopreservation; 3.6 Somatic Embryogenesis andSynthetic Seeds; 3.7 Somatic Embryogenesis andPlant Regeneration; References; Production ofSuperelite Planting Material Through InVitro Culturing inBanana; 1 Introduction. 6.2.7 Methylation/Demethylation ofDNA6.2.8 Altered Expression ofMultigene Families; 6.3 Nature ofSomaclonal Variation; 6.4 Significance ofSomaclonal Variation inCrop Improvement; 7 In Vitro Production ofHaploids; 7.1 Anther Culture; 7.1.1 Significance ofAnther Culture; 7.2 Isolated Microspore/Pollen Culture; 7.3 Unpollinated Ovary Culture; 7.4 Embryo Rescue fromWide Crosses; 7.4.1 Bulbosum Method; 7.4.2 Wheat Haploids fromWheat × Maize Crosses; 8 Embryo/Ovule/Ovary Culture forWide Hybridization; 9 Somatic Hybridization; 9.1 Protoplast Culture andSomatic Hybridization. 9.2 Significance inCrop Improvement10 In Vitro Production ofSecondary Metabolites; 11 Cryopreservation andInVitro Germplasm Storage; 12 Genetic Transformation forDeveloping Transgenic Crop Varieties; References; Micropropagation andSomatic Embryogenesis inSugarcane; 1 Micropropagation: AnIntroduction; 2 Micropropagation ofSugarcane: Historical Perspective; 2.1 Micropropagation Through Shoot-Tip Culture; 2.2 Micropropagation Through Apical/Axillary Bud Culture; 2.3 Micropropagation Through Spindle Leaf Segment Culture; 2.4 Micropropagation ofSugarcane forCommercial Plant Production.

Summary: During the past 15 years, cellular and molecular approaches have emerged as valuable adjuncts to supplement and complement conventional breeding methods for a wide variety of crop plants. Biotechnology increasingly plays a role in the creation, conservation, characterization and utilization of genetic variability for germplasm enhancement. For instance, anther/microspore culture, somaclonal variation, embryo culture and somatic hybridization are being exploited for obtaining incremental improvement in the existing cultivars. In addition, genes that confer insect- and disease-resistance, abiotic stress tolerance, herbicide tolerance and quality traits have been isolated and re-introduced into otherwise sensitive or susceptible species by a variety of transgenic techniques. Together these transformative methodologies grant access to a greater repertoire of genetic diversity as the gene(s) may come from viruses, bacteria, fungi, insects, animals, human beings, unrelated plants or even be artificially derived. Remarkable achievements have been made in the production, characterization, field evaluation and commercialization of transgenic crop varieties worldwide. Likewise, significant advances have been made towards increasing crop yields, improving nutritional quality, enabling crops to be raised under adverse conditions and developing resistance to pests and diseases for sustaining global food and nutritional security. The overarching purpose of this 3-volume work is to summarize the history of crop improvement from a technological perspective but to do so with a forward outlook on further advancement and adaptability to a changing world. Our carefully chosen "case studies of important plant crops" intend to serve a diverse spectrum of audience looking for the right tools to tackle complicated local and global issues.

Contents:
Intro; Dedication; Foreword; Preface; Contents; Contributors; About the Editors;
Chapter 1: Plant Genetic Transformation andTransgenic Crops: Methods andApplications; 1.1 Introduction; 1.2 Making Transgenic Plants; 1.2.1 Gene Transfer Methods inPlants; 1.2.2 Characterization ofPutative Transgenic Plants; 1.2.2.1 Phenotypic Assay; 1.2.2.2 Enzyme Assays; 1.2.2.3 PCR Analysis; 1.2.2.4 Southern Blot Analysis; 1.2.2.5 Western Blot Analysis; 1.2.2.6 Next-Generation Sequencing (NGS) Technologies; 1.2.2.7 Progeny Analysis; 1.2.2.8 Bioassay; 1.3 Engineering Crops forAgronomic Traits. 1.3.1 Development ofInsect-Resistant Plants1.3.1.1 Introduction ofBacterial Gene(s); 1.3.1.2 Introduction ofPlant Gene(s) forInsecticidal Proteins; 1.3.2 Development ofDisease-Resistant Plants; 1.3.2.1 Virus Resistance; Coat Protein-Mediated Resistance (CP-MR); Satellite RNA-Mediated Resistance; Antisense-Mediated Protection; Development ofResistance Using CRISPR/Cas9 Technology; 1.3.2.2 Fungal Resistance; Antifungal Protein-Mediated Resistance; Antifungal Compound-Mediated Resistance; 1.3.2.3 Bacterial Resistance; 1.3.3 Development ofHerbicide-Resistant Plants. 1.3.3.1 Transfer ofGene Whose Enzyme Product Detoxifies theHerbicide (Detoxification)1.3.3.2 Transfer ofGene Whose Enzyme Product Becomes Insensitive toHerbicide (Target Modification); 1.3.4 Development ofPlants Resistant toVarious Abiotic Stresses; 1.3.5 Development ofMale Sterile andRestorer Lines forHybrid Seed Production; 1.3.6 Improvement in Nutritional Quality andMolecular Farming/Pharming; 1.3.7 Biosafety Concerns ofTransgenic Plants; References. 2.5 Conclusion andFuture PerspectivesReferences;
Chapter 3: RNA Interference: APromising Approach forCrop Improvement; 3.1 Introduction; 3.2 RNA Interference (RNAi): siRNAs andmiRNAs; 3.3 RNAi forCrop Improvement; 3.3.1 Biotic Stress Resistance; 3.3.2 Abiotic Stress Tolerance; 3.3.3 Increasing Nutritional Value; 3.3.4 Increase inShelf Life ofFruits; 3.3.5 Production ofSeedless Fruits; 3.3.6 Modification ofFlower Color; 3.3.7 Development ofMale Sterile Lines; 3.3.8 Production ofSecondary Metabolites; 3.3.9 Removal ofAllergens fromFood Crops; 3.3.10 Change inPlant Architecture.
Chapter 2: Virus Induced Gene Silencing Approach: APotential Functional Genomics Tool forRapid Validation ofFunction ofGenes Associated withAbiotic Stress Tolerance inCrop Plants2.1 Introduction; 2.2 Application ofVIGS Technology to Study Function ofGenes Responsive toVarious Abiotic Stresses; 2.2.1 Drought, Salinity, andOsmotic Stress Tolerance; 2.3 Advantages ofUsing VIGS to Study Abiotic Stress Tolerance Mechanisms inCrop Plants; 2.4 Limitations ofVIGS inStudying Abiotic Stress Tolerance Mechanisms andPossible Approaches toOvercome theLimitations.

Summary: During the past 15 years, cellular and molecular approaches have emerged as valuable adjuncts to supplement and complement conventional breeding methods for a wide variety of crop plants. Biotechnology increasingly plays a role in the creation, conservation, characterization and utilization of genetic variability for germplasm enhancement. For instance, anther/microspore culture, somaclonal variation, embryo culture and somatic hybridization are being exploited for obtaining incremental improvement in the existing cultivars. In addition, genes that confer insect- and disease-resistance, abiotic stress tolerance, herbicide tolerance and quality traits have been isolated and re-introduced into otherwise sensitive or susceptible species by a variety of transgenic techniques. Together these transformative methodologies grant access to a greater repertoire of genetic diversity as the gene(s) may come from viruses, bacteria, fungi, insects, animals, human beings, unrelated plants or even be artificially derived. Remarkable achievements have been made in the production, characterization, field evaluation and commercialization of transgenic crop varieties worldwide. Likewise, significant advances have been made towards increasing crop yields, improving nutritional quality, enabling crops to be raised under adverse conditions and developing resistance to pests and diseases for sustaining global food and nutritional security. The overarching purpose of this 3-volume work is to summarize the history of crop improvement from a technological perspective but to do so with a forward outlook on further advancement and adaptability to a changing world. Our carefully chosen "case studies of important plant crops" intend to serve a diverse spectrum of audience looking for the right tools to tackle complicated local and global issues.

Contents:
Intro; Dedication; Foreword; Preface; Contents; Contributors; About the Editors;
Chapter 1: Marker-Assisted Breeding for Abiotic Stress Tolerance in Crop Plants; 1.1 Introduction; 1.2 Steps in Marker-Assisted Selection (MAS); 1.2.1 Selection of Plants with Desired Morphological Traits; 1.2.2 Development of Breeding Population; 1.2.3 Marker-Assisted Selection of Plants with Desired Traits; 1.2.4 Marker Validation; 1.2.5 Correlation with Morphological Traits; 1.3 MAB for Abiotic Stress Tolerance in Major Crop Plants; 1.3.1 Rice; 1.3.2 Wheat; 1.3.3 Maize; 1.3.4 Chickpea; 1.3.5 Common Bean. 1.3.6 Soybean Al Tolerance1.3.7 Pea; 1.4 Conclusion; References;
Chapter 2: Dynamics of Salt Tolerance: Molecular Perspectives; 2.1 Introduction; 2.2 Effect of Salinity on Plants; 2.2.1 Germination and Growth; 2.2.2 Effect of Salinity on Photosynthesis and Photosynthetic Pigments; 2.2.3 Water Relation; 2.3 Mechanism of Salt Tolerance; 2.3.1 Tissue Na+ Accumulation as an Indicator of Salt Tolerance; 2.3.2 Na+ Exclusion from Roots; 2.3.3 Sequestration of Na+ into Vacuoles; 2.3.4 Enhanced Tissue Tolerance to High Na+ Concentrations; 2.3.5 Cl ̄Toxicity During Salt Stress. 2.4 Conclusions and Future PerspectivesReferences;
Chapter 3: Marker-Assisted Breeding for Disease Resistance in Crop Plants; 3.1 Introduction; 3.2 Benefits of MAS; 3.3 Limits of MAS; 3.4 Case Study of MAS; 3.4.1 SCN Resistance Breeding; 3.5 Marker Discovery; 3.6 Confirmation of Parental Polymorphism; 3.7 High-Throughput Marker Screening; 3.8 Using Marker Data to Inform Selections; 3.9 MAS Considerations; 3.10 Genomic Selection in Crop Breeding; 3.11 Statistics of Prediction Models; 3.12 Factors Affecting Prediction Accuracy; 3.12.1 Training Population Size. 3.12.2 The Extent of LD Between the Markers and the QTL3.12.3 Trait Heritability; 3.12.4 Number of QTL and the Corresponding Effects; 3.13 Conclusions; References;
Chapter 4: Morpho-Physiological Traits and Molecular Intricacies Associated with Tolerance to Combined Drought and Pathogen Stress in Plants; 4.1 Introduction; 4.2 Morpho-Physiological Traits that Likely Govern Plant Response to Combined Stress; 4.2.1 Cell Membrane Stability; 4.2.2 Leaf Water Potential; 4.2.3 Stomatal Movement; 4.2.4 Root Length; 4.3 Impact of Combined Stress on Other Morpho-Physiological Parameters. 4.3.1 Leaf Area4.3.2 Leaf Greenness; 4.3.3 Canopy Temperature; 4.3.4 Time to Anthesis; 4.4 More Potential Traits: Analysis from Individual Stress Studies; 4.4.1 Trichome Type and Density; 4.4.2 Cuticular Wax Composition; 4.5 Molecular Mechanism Governing Traits Imparting Combined Stress Tolerance in Plants; 4.6 Future Perspectives; References;
Chapter 5: Genome Editing for Crop Improvement: Status and Prospects; 5.1 Introduction; 5.1.1 Zinc-Finger Nucleases (ZFNs); 5.1.2 Transcription Activator-Like Effector Nucleases (TALENs); 5.1.3 CRISPR/Cas System.

Summary: The depletion of petroleum-derived fuel and environmental concerns have prompted many millennials to consider biofuels as alternative fuel sources. But completely replacing petroleum-derived fuels with biofuels is currently impossible in terms of production capacity and engine compatibility. Nevertheless, the marginal replacement of diesel with biofuel could delay the depletion of petroleum resources and abate the radical climate change caused by automotive pollutants. Energy security and climate change are the two major driving forces for worldwide biofuel development, and also have the potential to stimulate the agro-industry. The development of biofuels as alternative and renewable sources of energy has become critical in national efforts towards maximum self-reliance, the cornerstone of our energy security strategy. At the same time, the production of biofuels from various types of biomass such as plants, microbes, algae and fungi is now an ecologically viable and sustainable option. This book describes the biotechnological advances in biofuel production from various sources, while also providing essential information on the genetic improvement of biofuel sources at both the conventional and genomic level. These innovations and the corresponding methodologies are explained in detail.

Contents:
Chapter 1: Biofuels: perspective for sustainable development and climate change mitigation
Chapter 2: Nanoparticles for Sustainable Bioenergy and Biofuel Production
Chapter 3: Bio-hydrogen: technology developments in microbial fuel cells and their future prospects
Chapter 4: Recent Advances in Genetic Improvement of Jatropha curcas: a potent biodiesel plant
Chapter 5: Catalytic approach for production of hydrocarbon rich bio-oil from a red seaweed species
Chapter 6: Seaweed biomass and microbial lipids as a source of biofuel
Chapter 7: Microbial Biofuels: an economic and eco-friendly approach
Chapter 8: Biofuels: sources, modern technology developments and views on bioenergy management
Chapter 9: Integrating omics and microbial biotechnology for the production of Biofuel
Chapter 10: An Overview on Biomass of Bamboo as a Source of Bioenergy
Chapter 11: Advances and challenges in sugarcane biofuel development.

Summary: "This book highlights some of the most important biochemical, physiological and molecular aspects of plant stress, together with the latest updates. It is divided into 14 chapters, written by eminent experts from around the globe and highlighting the effects of plant stress (biotic and abiotic) on the photosynthetic apparatus, metabolites, programmed cell death, germination etc. In turn, the role of beneficial elements, glutathione-S-transferase, phosphite and nitric oxide in the adaptive response of plants under stress and as a stimulator of better plant performance is also discussed. A dedicated chapter addresses research advances in connection with Capsicum, a commercially important plant, and stress tolerance, from classical breeding to the recent use of large-scale transcriptome and genome sequencing technologies. The book also explores the significance of the liliputians of the plant kingdom (Bryophytes) as biomonitors/bioindicators, and general and specialized bioinformatics resources that can benefit anyone working in the field of plant stress biology. Given the information compiled here, the book will offer a valuable guide for students and researchers of plant molecular biology and stress physiology alike"--Print version, page 4 of cover.

Contents:
Plants Stress Responses to Drought: Physiological, Biochemical and Molecular Basis
Photosynthesis and Abiotic Stress in Plants
Ecotoxicological effects of insecticides in plants assessed by germination and other phytotoxicity tools
Variation in Plant Bioactive Compounds and Antioxidant Activities under Salt Stress
Response of plants to salinity stress and the role of salicylic acid in modulating tolerance mechanisms: physiological and proteomic approach
The role of beneficial elements in triggering adaptive responses to environmental stressors and improving plant performance
Plant adaptation to stress conditions: the case of Glutathione S-transferases (GSTs)
Phosphite as an inductor of adaptive responses to stress and stimulator of better plant performance
Nitric oxide and reactive oxygen species interactions in plant tolerance and adaptation to stress factors
Involvement of Reactive Species of Oxygen and Nitrogen in Triggering Programmed Cell Death in Plants
Progress and prospects in Capsicum breeding for biotic and abiotic stresses
MicroRNA (miRNA) and Small interfering RNA (siRNA)
Biogenesis and functions in plants
Bryomonitoring of Environmental Pollution
Bioinformatics resources for the stress biology of plants.

Summary: This volume is a self-contained companion piece to Studying Vibrational Communication, published in 2014 within the same series. The field has expanded considerably since then, and has even acquired a name of its own: biotremology. In this context, the book reports on new concepts in this fascinating discipline, and features chapters on state-of-the art methods for studying behavior tied to substrate-borne vibrations, as well as an entire section on applied biotremology. Also included are a historical contribution by pioneers in the field and several chapters reviewing the advances that have been made regarding specific animal taxa. Other new topics covered are vibrational communication in vertebrates, multimodal communication, and biotremology in the classroom, as well as in art and music. Given its scope, the book will appeal to all those interested in communication and vibrational behavior, but also to those seeking to learn about an ancient mode of communication.

Contents:
Part I. Studying Vibrational Behavior: Ideas, Concepts and History
Quo Vadis, Biotremology?
What is Biotremology?
Biotremology and Sensory Ecology
Body Tremulations and their Transmission as Vibrations for Short Distance Information Transfer between Ephippiger Male and Female
Part II. The State of the Field: Concepts and Frontiers in Vibrational Behavior
Physical Basis of Vibrational Behaviour: Channel Properties, Noise and Excitation Signal
Copulatory Courtship with Vibrational Signals
Stinkbugs: Multisensory Communication with Chemical and Vibratory Signals Transmitted Through Different Media
Part III. Practical Issues in Studying Vibrational Behavior
Practical Issues in Studying Natural Vibroscape and Biotic Noise
Automated Vibrational Signal Recognition and Playback
Part IV. Vibration Detection and Orientation
Mechanisms of Vibration Detection in Mammals
Determining Vibroreceptor Sensitivity in Insects: The Influence of Experimental Parameters and Recording Technique
Directionality in Insect Vibration Sensing: Behavioral Studies of Vibrational Orientation
Part V. Biology and Evolution of Vibrational Behavior in Some Well-Studied Taxa
Vibrational Behavior in Elephants
Seismic Communication in the Amphibia with Special Emphases on the Anura
Vibrational Communication in Heelwalkers (Mantophasmatodea)
Vibrational Behavior in Termites (Isoptera)
Part VI. Applied Biotremology
Mating Disruption by Vibrational Signals: State of the Field and Perspectives
Mating Disruption by Vibrational Signals: Applications for Management of the Glassy-winged Sharpshooter
Can Vibrational Playback Improve Control of an Invasive Stink Bug?
Vibrational Trapping and Interference with Mating of Diaphorina citri
Vibrational Behavior in Bark Beetles: Applied Aspects
Part VII. Outreach and Resources
Shaking it up in the Classroom: Coupling Biotremology and Active Learning Pedagogy to Promote Authentic Discovery
Call for the Establishment of a VibroLibrary at the Animal Sound Archive Berlin
The Arachnid Orchestras: Artistic Research in Vibrational Interspecies Communication
Bioacoustic Music Inspired by Biotremological Research.

Summary: This book examines in detail the diagnostic approach to manic depressive (bipolar) illness, with special reference to the borderline zones with unipolar depression and schizoaffective disorder. Among other diagnostic issues considered are mixed episodes (often misdiagnosed by psychiatrists), rapid cycling, and the confusion with personality disorders. Within the context of diagnosis and understanding of the dynamics of bipolar disorder, temperament, character, and personality are all extensively discussed. Neurocognitive deficit and disability are covered, as are elements of evolutionary biology and behavior. With regard to treatment, the major focus is on evidence-based therapy, with reference to the results of randomized controlled trials and meta-analyses; in addition, contemporary guidelines and future trends are examined. Careful consideration is also given to the psychosocial treatment approach and issues relating to societal and economic costs and burdens.

Contents:
Introduction
Historical perspective
Clinical description
Comorbid conditions
Classification
Epidemiology
Etiopathogenesis (psychodynamic theories, biological models, genetics)
Etiopathogenesis (psychodynamic theories, biological models, genetics)
Assessment (psychometric, neuropsychological, scales)
Therapy
Biological therapies (separate for mania, depression and maintenance)
Randomized Controlled Trials (RCTs)
Meta-analysis
Open trials
Review and opinion papers
Pharmacoepidemiologic data
Psychosocial therapies
Treatment guidelines
Cautions for pharmaceutical treatment in bipolar patients
Switching to the opposite pole
Psychogeriatric issues
Suicidality
Gender issues
Pediatric bipolar disorder
Conclusion.

Summary: Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry. Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously. With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.

Contents:
Intro
Preface
Contents
The Neurobiology of Bipolar Disorder
1 Introduction
2 Neurotransmitters
2.1 Serotoninergic System
2.2 Dopaminergic System
2.3 Norepinephrinergic System
2.4 GABAergic System
2.5 Glutamatergic System
3 Intracellular Signalling
4 Adenylate Cyclase Signalling Pathway
5 Neurotrophins and Neurogenesis
6 Neuroendocrine
7 Conclusion
References
The Role of Stress in Bipolar Disorder
1 Introduction
1.1 Activation of Hormonal Systems After Stress
1.2 Stress Hormone Receptors 2 Stress Hormone Actions on the Brain in Healthy Individuals
2.1 Cellular Effects of Stress Hormones on Brain Circuits
2.2 Neuronal Circuits and Cognitive Function
3 Changes in Stress Responsiveness in Bipolar Disorder
3.1 Imbalance in the Stress System: Importance of Genetic and (Early) Life History
3.2 Changes in the HPA Axis in Bipolar Disorder Patients
4 Changes in Cognitive Function in Bipolar Disorder Related to Stress
4.1 Time-Dependent Changes in Cognitive Processing Following Stress in BD Patients 3.1.2 Creatine Kinase
3.1.3 Calcium
3.1.4 Increased Oxidative Stress
3.1.5 Neurotransmitters
3.1.6 Brain-Derived Neurotrophic Factor (BDNF)
3.1.7 NAA
3.1.8 Bcl-2
3.2 Mitochondrial Genes
4 How Conventional Drugs for Bipolar Disorder Relate to Mitochondrial Functioning
5 Mitochondrial Potential Treatments
5.1 Likely Beneficial
5.1.1 PPAR Agonists
5.1.2 Minocycline
5.1.3 N-Acetyl-Cysteine (NAC)
5.1.4 Co-enzyme Q10
5.1.5 Melatonin
5.2 Theoretically Beneficial, but No Studies Have Been Published
5.2.1 Ebselen
5.2.2 Mangosteen 4.2 Network Function in BP Patients and Individuals at Risk for Psychopathology
5 Concluding Remarks
References
The Role of Genetics in Bipolar Disorder
1 Introduction: Why Genetics Matters in the Susceptibility to Bipolar Disorder?
2 Bipolar Disorder Is Heritable: Twin, Adoption, and Family Studies
3 How Many Genes Modulate the Risk of Bipolar Disorder? Linkage Studies, Candidate Gene Studies, and Genome-Wide Association S...
4 Genetic Overlap Between Bipolar Disorder and Other Brain Disorders: Disorder-Specific or General Genetic Influences? 5 The Role of Rare Genetic Variants
6 Gene x Environment Studies
7 Nongenetic Mechanisms Contributing to the Regulation of Gene Expression: Epigenetics
8 Current and Future Lines of Research
9 Conclusion
References
Targeting Mitochondrial Dysfunction for Bipolar Disorder
1 The Mitochondria
1.1 Mitochondria as an Energy Source
1.2 Other Functions of Mitochondria
2 Reactive Oxygen Species and Oxidative Stress
3 Mitochondria in Bipolar Disorder
3.1 Possible Mechanisms of Mitochondrial Dysfunction in Bipolar Disorder
3.1.1 A Shift from OXPHOS to Glycolysis

Summary: Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness. Highlights diverse translational methodologies, including functional and structural neuroimaging, neuropsychological testing and integrated genomics. Examines molecular trajectories in youth with bipolar disorder and unaffected youth at high risk for developing bipolar disorder. Explores the interaction between genomic and environmental influences that shape behavior

Summary: This book will provide the state-of-the-art research on topics involved in the ecology and conservation of birds of prey. With chapters authored by the most recognized and prestigious researchers on each of the fields, this book will become an authorized reference volume for raptor biologists and researchers around the world.

Contents:
Section 1
General biology
1 Recent advances in raptor taxonomy and phylogeny
2 Breeding and nesting biology
3 Population ecology of birds of prey
4 Behavioural ecology of raptors
5 Raptor migration
6 Dispersal in raptors
Section 2
Raptors in human landscapes
7 Raptors and people: an ancient relationship persisting today
8 Conflicts between raptors and humans
9 Causes and consequences of urban living in raptors
10 Birds of prey in agricultural landscapes, the role of agriculture expansion and intensification
11 Toxicology of birds of prey
12 Lead contamination in birds of prey
13 Raptors electrocutions and power lines collisions
14 Impact of renewable energy sources on birds of prey
15 Use of drone imagery for research and conservation of birds of prey
Section 3
Conservation and status of raptors around the world
16 Distribution models for raptor research and conservation
17 Conservation genetics in birds of prey
18 Conservation status of Neotropical raptors
19 Conservation priorities for raptors across Asia
20 Conservation of African raptors
21 Conservation status and threats of New World vultures
22 Old vultures in a changing environment
23 Past, present and future of raptors on islands
24 Raptor conservation in practice.

Summary: This book presents the epidemiology of birth defects and their public health and social implications in India. As neglected childhood disorders, birth defects remain invisible in global maternal and child health dialogues. Birth defects services are emerging in India. This book approaches birth defects from a public health perspective, identifying the core functions of a birth defects service. Keeping in mind the complex task of providing multidisciplinary services for children with disabilities and complex medical conditions, the book examines the basic public health activities that have been put in place to address these conditions in India. The book describes birth defects surveillance and the challenges of acquiring accurate and timely data on birth defects against the background of India's mixed health system. It discusses opportunities for prevention of birth defects and describes the structure and function of an emergent genetic service. It explores issues related to an integrated service for children with special healthcare needs, such as screening, early intervention, and rehabilitation. Furthermore, it describes the impact of these conditions on caregivers, including birth defects stigma. This book not only addresses a knowledge gap in the field of public health in India, but also explores the broader issues of services for children with disabilities and disabling conditions in low and low-middle income settings where access to health care is not universal. Given the depth and breadth of its coverage, the book offers an essential resource for birth defects researchers, researchers in the field of maternal and child health, public health/ global health, disability researchers, and researchers from the fields of rehabilitation sciences, nursing and anthropology. This book will be a valuable read for social medicine/community medicine departments, global health courses, and public health schools in India and other low middle-income countries.

Contents:
Intro
Preface
Acknowledgements
Introduction: Birth Defects and Public Health in Low and Middle-Income Countries
Contents
Editor and Contributors
Abbreviations
List of Figures
List of Tables
List of Boxes
Part I A Public Health Approach
1 Birth Defects: A Public Health Approach
The Need for Birth Defects Services in LMICs
Individual, Health and Social Welfare System Impact
Magnitude of Congenital Anomalies
Epidemiological Transition
A Public Health Framework
Birth Defect Surveillance
Prevention of Birth Defects Integrated medical and rehabilitation services
Other Public Health Activities
The World Health Assembly Resolution on Birth Defects
India as an Example of a LMIC
Socio-demographic and Health Indicators
Socio-demographic Index and Epidemiological Transition
Health System
Maternal and Child Health Services
References
2 Some Common Birth Defects
Section I : Common Congenital Anomalies/Malformations
Congenital Heart Defects
Orofacial Clefts
Spina Bifida and Neural Tube Defects
Hydrocephalus, Macrocephaly, Microcephaly Clubfoot (Congenital Talipes Equinovarus)
Developmental Dysplasia of the Hip
Congenital Limb Defects
Polydactyly
Section II : Developmental (Neuromotor) Disabilities
Intellectual Disability
Down Syndrome
Attention-Deficit/Hyperactivity Disorder
Autism Spectrum Disorders
Cerebral Palsy
Congenital Hearing Impairment
Vision Impairment/Blindness
Section III : Common Single Gene Disorders
Hemoglobinopathies
Hemophilia
Muscular Dystrophy
Achondroplasia
Conclusion
References 3 Thalidomide: Understanding the Responsibilities of a Birth Defects Service
Thalidomide
Thalidomide Distribution Across the World
Thalidomide Embryopathy/Syndrome
Health and Social Impact of Thalidomide
Clinical Needs of Children
Impact of Disability: Schooling
Impact on Parents
Health and Welfare Needs with Ageing
The Response to the Thalidomide Tragedy
Health and Social Sector Service Response
Birth Defects Surveillance
Drug Regulation
Abortion Legislation
Compensation and Economic Support
Regulated Reintroduction of Thalidomide Thalidomide in Developing Countries
Lessons for a Birth Defects Service
Zika Virus and the Public Health Response
Congenital Zika Virus Syndrome
Public Health Response
Health System Challenges
Impact on Families
References
Part II Surveillance, Registries and Magnitude
4 Birth Defects Surveillance in India
Background
Birth Defects Surveillance
Birth Defects Surveillance: Factors Affecting Reporting of Prevalence Data
Birth Defects Surveillance in LMICs
Birth Defects Surveillance in India
Summary and Conclusion
References

Summary: This book focusing on the bitter gourd genome is the first comprehensive compilation of knowledge on the botany, cytogenetical analysis, genetic resources and diversity, traditional breeding, tissue culture and genetic transformation, whole genome sequencing and comparative genomics in the Cucurbitaceae family. It discusses the biochemical profile of the bioactives present in this horticultural crop, used both as a vegetable and as a medicine, and also addresses sex determination in bitter gourd. Written by respected international experts, the book is useful to students, teachers and scientists in academia, as well as seed companies and pharmaceutical industries.

Contents:
Introduction
Botanical descriptions
Medicinal properties: bioactives and their actions
Genetic resources and genetic diversity
Cytogenetical analysis of bitter gourd genome
Sex determination
Tissue culture, genetic engineering & nanotechnology
Classical genetics and traditional breeding
Molecular linkage mapping: Map construction and mapping of genes/QTLs
Genome sequence and its comparative study with other Cucurbitaceae genome
Functional genomics: metabolomics, transcriptomics (including biochemical study of interaction with parasite)
Future Prospects.

Summary: "Drawing on narratives from hundreds of Black, Latinx, and Indigenous individuals, Ebony Omotola McGee examines the experiences of underrepresented racially minoritized students and faculty members who have succeeded in STEM. Based on this extensive research, McGee advocates for structural and institutional changes to address racial discrimination, stereotyping, and hostile environments in an effort to make the field more inclusive. Black, Brown, Bruised reveals the challenges that underrepresented racially minoritized students confront in order to succeed in these exclusive, usually all-White, academic and professional realms. The book provides searing accounts of racism inscribed on campus, in the lab, and on the job, and portrays learning and work environments as arenas rife with racial stereotyping, conscious and unconscious bias, and micro-aggressions. As a result, many students experience the effects of a racial battle fatigue--physical and mental exhaustion borne of their hostile learning and work environments--leading them to abandon STEM fields entirely. McGee offers policies and practices that must be implemented to ensure that STEM education and employment become more inclusive including internships, mentoring opportunities, and curricular offerings. Such structural changes are imperative if we are to reverse the negative effects of racialized STEM and unlock the potential of all students to drive technological innovation and power the economy."--Amazon.

Contents:
Will white supremacy end America's STEM supremacy?
The plight of the underrepresented in STEM higher education and workforce
The stress of success for the underrepresented and minoritized in STEM
Why justice-oriented STEM is the key to getting and keeping students of color in STEM and, oh yeah, saving our planet, too!
Evaluating efforts to broaden STEM participation
Next steps for STEM leadership: practical suggestions.

Summary: "Black Appetite. White Food. invites educators to explore the nuanced manifestations of white privilege as it exists within and beyond the classroom. Renowned speaker and author Jamila Lyiscott provides ideas and tools that teachers, school leaders, and professors can use for awareness, inspiration, and action around racial injustice and inequity. Part I of the book helps you ask the hard questions, such as whether your pedagogy is more aligned with colonialism than you realize and whether you are really giving students of color a voice. Part II offers a variety of helpful strategies for analysis and reflection. Each chapter includes personal stories, frank discussions of the barriers you may face, and practical ideas that will guide you as you work to confront privilege in your classroom, campus, and beyond."-- Provided by publisher.

Summary: Recent developments in the field of nutrition have led to increased interest in herbs and medicinal plants as phytochemical-rich sources for functional food, nutraceuticals, and drugs. As research sheds light on the therapeutic potential of various bioactive phytochemicals, the demand for plant extracts and oils has increased. Black cumin or black seeds (Nigella sativa) have particularly widespread nutritional and medicinal applications. In traditional medicine, black seeds are used to manage fatigue and chronic headache. Black seed oil is used as an antiseptic and analgesic remedy and for treatment of joint's pain and stiffness and can be mixed with sesame oil to treat dermatosis, abdominal disorders, cough, headache, fever, liver ailments, jaundice, sore eyes, and hemorrhoids. Thymoquinone, the main constituent in black seed volatile oil, has been shown to suppress carcinogenesis. Black cumin (Nigella sativa) seeds: Chemistry, Technology, Functionality, and Applications presents in detail the chemical composition, therapeutic properties, and functionality of high-value oils, phytochemicals, nutrients, and volatiles of the Nigella sativa seed. Organized by formulation (seeds, fixed oil, essential oil, and extracts), chapters break this seed down into its chemical constituents and explore their role in the development of pharmaceuticals, nutraceuticals, novel food, natural drugs, and feed. Following numerous reports on the health-promoting activities of Nigella sativa, this is the first comprehensive presentation of the functional, nutritional, and pharmacological traits of Nigella sativa seeds and seed oil constituents.

Contents:
1. Introduction to black cumin (Nigella sative): Chemistry, Technology, Functionality and Applications
Section 1. Nigella sative seeds: Cultivation, Composition and Applications
2. Effect of cultivation, fertilization and irrigation practices on Nigella sative yield and quality
3. Morphological characters of Nigella sativa
4. Micro and macroscopic characterization of traded Nigella sativa seeds using applied systematics techniques
5. Composition of Nigella sativa seeds
6. Nigella sativa seed peptides (Thionins)
7. Black cumin polysaccharides
8. Thymoquinone: Chemistry and cunctionality
9. Novel Prospective of Nigella sativa Essential Oil Analysis, Culinary and Medicinal Uses
10. Rediscovering Nigella Seeds Bioactives Chemical Composition using Metabolomics Technologies
11. Health promoting activities of Nigella sativa seeds
12. Nigella sativa seed extract in green synthesis and nanocomposite
13. Food applications of Nigella sative seeds
14. Nutraceutical importance and applications of Nigella sativa seed flour
15. Nigella sativa seed cake: nutraceutical significance and applications in the food and cosmetic industry
16. Nigella sative seeds in cosmetic products
17. Nigella sativa supplementation in ruminant diets: production, health, and environmental perspectives
18. Nigella sativa seeds and its derivatives in poultry feed
19. Nigella sative Seeds and Its Derivatives in Fish Feed
Section 2: Nigella sative fixed oil: Chemistry, Technology, Functionality and Applications
20. Composition and Functionality of Nigella sativa Fixed Oil
21. Effect of processing on the composition and quality of Nigella sativa fixed oil
22. Food applications of Nigella sativa Fixed Oil
23. Health-Promoting Activities of Nigella sativa Fixed Oil
24. Micro- and Nano-encapsulation of Nigella sativa Oil
25. Biodiesel Production Potential of Nigella sativa Oil
Section 3: Nigella sative essential oil: Chemistry, Technology, Functionality and Applications
26. Composition and functionality of Nigella sativa essential oil
27. Effect of processing on the composition and quality of Nigella sativa essential oil
28. Food applications of Nigella sativa essential oil
29. Health-promoting activities of Nigella sativa essential oil
Section 4: Nigella sative seed extracts: Chemistry, Technology, Functionality and Applications
30. Composition and Functionality of Nigella sativa Seed Extracts
31. Nigella sativa seed extracts in functional foods and nutraceutical applications
32. Health promoting activities of Nigella sativa seed extracts.

Summary: In these twelve deeply personal, connected essays, Bernard details the experience of growing up black in the south with a family name inherited from a white man, surviving a random stabbing at a New Haven coffee shop while taking graduate studies at Yale, marrying a white man from the north and bring him home to her family, adopting two babies from Ethiopia, and living and teaching in a primarily white New England college town. Each of these essays goes beyond a narrative of black innocence and white guilt and sets out to discover a new way of telling the truth as the author has lived it.

Contents:
Beginnings
Scar tissue
Teaching the N-word
Interstates
Mother on Earth
Black is the body
Skin
White friend
Her glory
Motherland
Going home
People like me
Epilogue: my turn.

Summary: "Tracker is known far and wide for his skills as a hunter: "He has a nose," people say. Engaged to track down a mysterious boy who disappeared three years earlier, Tracker breaks his own rule of always working alone when he finds himself part of a group that comes together to search for the boy. The band is a hodgepodge, full of unusual characters with secrets of their own, including a shape-shifting man-animal known as Leopard. As Tracker follows the boy's scent -- from one ancient city to another; into dense forests and across deep rivers -- he and the band are set upon by creatures intent on destroying them. As he struggles to survive, Tracker starts to wonder: Who, really, is this boy? Why has he been missing for so long? Why do so many people want to keep Tracker from finding him? And perhaps the most important questions of all: Who is telling the truth, and who is lying? Drawing from African history and mythology and his own rich imagination, Marlon James has written a novel unlike anything that's come before it: a saga of breathtaking adventure that's also an ambitious, involving read. Defying categorization and full of unforgettable characters, Black Leopard, Red Wolf is both surprising and profound as it explores the fundamentals of truth, the limits of power, and our need to understand them both."--Publisher's description

Contents:
A dog, a cat, a wolf, and a fox
Malakin
One child more than six
White science and black math
Here is one oriki
Death wolf.

Summary: "In the wake of the murder of George Floyd in Minneapolis, the debate between proponents of Black Lives Matter and All Lives Matter has been reignited. For proponents of Black Lives Matter, the slogan All Lives Matter is not a call for inclusiveness but a criticism of the Black Lives Matter movement. On the other hand, advocates of All Lives Matter insist their slogan is about diversity and colorblindness. The contributors included in Black Lives Matter vs. All Lives Matter: A Multidisciplinary Primer approach the subject from fields as wide ranging as sociology, mathematics, linguistics, business, politics, and psychology, to name a few. This collection adds complexity and international perspectives to the debate, allowing these seemingly simple quarrels over phrasing to be unpacked from many angles. A refreshing variety of looks at one of the defining social movements of the last decade and the reaction to it, this collection will be valuable to those seeking to understand these movements in ways beyond how they are typically framed."-- Provided by publisher

Contents:
General introduction / Abdul Karim Bangura
Religious perspective / Simon Gisege Omare
Literary perspective / Saidu Bangura
Mathematical perspective / Abdul Karim Bangura
Public administration / policy perspective / Rachael M. Rudolph
Linguistic perspective / Lilian Achieng' Magonya and Pamela Anyango Oloo
Sociological perspective / Banson Waiganjo Kanyingi
Gender and sexuality perspective / Cecy Edijala Balogun
Economic perspective / Abdul Amin Kamara
Psychological perspective / Lilian Anyango Olick
Business perspective / Olumuyiwa Adekunle Kehinde
Political perspective / Omosefe Oyekanmi
Juvenile justice perspective / Gerald K. Fosten
General conclusion / Abdul Karim Bangura.

Summary: "When Chad Sanders landed his first job in lily-white Silicon Valley, he quickly concluded that to be successful at work meant playing a certain social game. Each meeting was drenched in white slang and the privileged talk of international travel or folk concerts in San Francisco, which led Chad to believe he needed to emulate whiteness to be successful. So Chad changed. He changed his wardrobe, his behavior, his speech--everything that connected him with his Black identity. And while he finally felt included, he felt awful. So he decided to give up the charade. He reverted back to the methods he learned at the dinner table, or at the Black Baptist church where he'd been raised, or at the concrete basketball courts, barbershops, and summertime cookouts. And it paid off. Chad began to land more exciting projects. He earned the respect of his colleagues. Accounting for this turnaround, Chad believes, was something he calls Black Magic, namely resilience, creativity, and confidence forged in his experience navigating America as a Black man. Black Magic has emboldened his every step since, leading him to wonder: Was he alone in this discovery? Were there others who felt the same? In essays, Chad dives into his formative experiences to see if they might offer the possibility of discovering or honing this skill. He tests his theory by interviewing Black leaders across industries to get their take on Black Magic. Black Magic explores Black experiences in predominantly white environments and demonstrates the risks of self-betrayal and the value of being yourself"--adapted from dust jacket.

Contents:
Home and neighborhood
Grade school : gifted and talented programs, private school, and separation
College : HBCUs, PWIs, and higher learning
Work
Spirit : church, God, and faith.

Summary: When Tweedy began medical school, he envisioned a bright future where his segregated, working-class background would become irrelevant. Instead he found himself grappling with race, bias, and the unique health problems of black Americans, and met a professor who bluntly questioned whether he belonged in medical school. In examining the complex ways in which both black doctors and patients must navigate the difficult and often contradictory terrain of race and medicine, he illustrates the complex social, cultural, and economic factors at the root of most health problems in the black community.

Contents:
Introduction
Disparities. People like us ; Baby mamas ; Charity care ; Inner-city blues
Barriers. Confronting hate ; When doctors discriminate ; The color of HIV/AIDS
Perseverance. Matching ; Doing the right thing ; Beyond race.

Summary: Conogethes is a group of moths distributed in Austral-Asian region from India to New Guinea, the Solomon Islands and Australia. The moths are also found in Hawaii and Great Britain. Conogethes is mostly known for the economic impact of its larvae on agricultural crops. Substantial research has been undertaken in order to understand the biology of these harmful insects and to develop strategies to confine their impact. Research on chemical communication between males and females via sex pheromones is in progress. Recent research has also focused on the acoustic communication of Conogethes. The moths can feed on more than 200 plants in diversified habitats. The borer moths have become major pest on Horticultural, Agricultural, Avenue trees and forest trees. Its a pest of Quarantine importance as it has been found in Exportable commodities. The book contains 22 chapters from a dozen countries. The authors are from China, Vietnam, Australia, Sri Lanka, Malaysia, Norway etc. This is the first book on the pest globally where interesting insights are provided. This is one of the book of its kind on single pest dealing with almost all aspects of its biology and management on cultivated crops.

Contents:
Intro; Foreword; Preface; Acknowledgment; Contents; Editor and Contributors;
1: Moths of the Genus Conogethes: Taxonomy, Systematics, and Similar Species; 1.1 Introduction; 1.2 Host Plant Use; 1.3 Systematics and Delimitation; 1.4 Diagnosis; 1.5 Phylogenetic Relationships; References;
2: Molecular Status of Conogethes spp.: An Overview; 2.1 Introduction; 2.2 Biosystematics; 2.3 Molecular Identification; 2.3.1 Conogethes Barcode; 2.4 Japan; 2.5 India; 2.6 China; 2.7 New Zealand; 2.8 Other Molecular Works; References;
3: Conogethes sahyadriensis: A New Borer on Zingiberaceous Crop Plants from India; 3.1 Introduction; 3.2 Biosystematics; 3.3 Geographical Distribution and Host Range; 3.4 Molecular Characterization; 3.5 Seasonal Incidence and Crop Loss; 3.6 Mating and Feeding Behaviour; 3.7 Sex Pheromone Components; References;
4: Status of Shoot and Fruit Borer, Conogethes spp. (Crambidae: Lepidoptera) in Asia: Central, South, and the Southeast; 4.1 Introduction; 4.2 Afghanistan; 4.3 Bhutan; 4.4 Bangladesh; 4.5 Myanmar; 4.6 Nepal; 4.7 Maldives and Other Islands; 4.8 Networking; 4.9 Future Thrusts; References;
5: Research Progress of Conogethes punctiferalis (Lepidoptera: Crambidae) in China; 5.1 Introduction; 5.2 Distribution and Host Range; 5.3 Morphology; 5.4 Occurrence and Damage; 5.5 Host-Plant Interactions; 5.6 Artificial Diet; 5.7 Overwinter and Diapause; 5.8 Wolbachia Infection; 5.9 Genetic Diversity and Gene Flow; 5.10 Molecular Taxonomy; 5.11 Integrated Management; References;
6: Status of Conogethes punctiferalis (Guenée) in South of Vietnam; 6.1 Introduction; 6.2 Characteristics of C. punctiferalis (Guenée) in South of Vietnam; 6.2.1 Species of Genus Conogethes in South of Vietnam; 6.2.2 Synonyms; 6.2.3 Host Range; 6.2.4 Morphological Characteristics; 6.2.5 Biological Characteristics; 6.2.6 Natural Enemies; 6.3 Status of Conogethes punctiferalis (Guenée) on Crops in South Vietnam; 6.3.1 Durian; 6.3.1.1 Damage Symptoms; 6.3.1.2 Management; 6.3.2 Guava; 6.3.2.1 Damage Symptoms; 6.3.2.2 Management; 6.3.3 Longan; 6.3.3.1 Damage Characteristics; 6.3.3.2 Management; 6.3.4 Rambutan; 6.3.4.1 Damage Symptoms; 6.3.4.2 Management; 6.3.5 Soursop; 6.3.5.1 Damage Symptoms; 6.3.5.2 Management; 6.3.6 Ginger; 6.3.6.1 Damage Symptoms; 6.3.6.2 Management; References;
7: Status of Shoot and Fruit Borer, Conogethes punctiferalis, in Sri Lanka; 7.1 Introduction; 7.2 Life History; 7.3 Host Plant and Nature of Damage; 7.4 Conogethes on Teak; 7.5 Conogethes on Zingiberaceae; 7.6 Conogethes on Fruit Crops; 7.7 Management Practices; References;
8: Status and Management of Conogethes spp. in Malaysia; 8.1 Introduction; 8.2 Key Species; 8.3 Biogeography; 8.4 Host Range; 8.5 Economic Importance; 8.6 Bioecology; 8.7 Seasonality; 8.8 Management; References

Summary: "The classic text in black theology, with a new foreword by Peter J. Paris and a new afterword by Kelly Brown Douglas"-- Provided by publisher.

Summary: This socially conscious, culturally relevant book explores the little-known history and present climate of Black people in the medical field. It reveals the deficiencies in the American healthcare structure that have contributed to the mismanagement of healthcare in the Black population, and examines cross-currents that intersect with the major events in minority medical history. Illustrated across 10 expertly written chapters, this text features a longitudinal timeline with the presentation of evidence-based information drawn from historical, political, and clinical sources. The book begins with an analysis of diseases particularly prevalent in the Black community due to socioeconomic inequalities in available medical care. These diseases include sickle cell anemia, hypertension, heart failure, drug addiction, and HIV/AIDS. Bolstered by profiles of historically well-known Black physicians, stories of success in medical education, and the remarkable impact of Black medical organizations, subsequent chapters address the triumphs and tribulations of the Black medical professional in America. Concluding with an examination of the current health status of Black people in the United States, the book makes a case for future systemic improvements in healthcare delivery to minority communities. A unique, noteworthy reference, Blacks in Medicine: Clinical, Demographic, and Socioeconomic Correlations is written for a broad range of physicians and health providers, as well as professionals in the social sciences and public health.

Contents:
Ancient History as a Backdrop to Black Medical History
Beginning of Transoceanic Slave Transport
Initiation of the Transatlantic Slave Trade Between Africa and America
Poor Medical Treatment of Slaves and Its Consequences
Emergence of the First Black Doctors Trained in Medical Schools
Beginning of Black Medical Autonomy and Self-Determination
Destructive Effects of Discrimination and Institutional Racism
Extreme Medical Hardship Period
Development of Social Welfare
Development of Healthcare Reform.

Contents:
Sect.1: Basics
1. Epidermis in Clinical Dermatology
2. Lesion Description/Terminology
3. Diagnostic Culture and Identification (Bacterial and Fungal)
4. Obtaining a Diagnostic Biopsy
5. Practical Cytology
6. Symptom Checker (Lesional and Regional Dermatoses)
7. Antibiotic Stewardship and Emerging Resistant Bacterial Infections
Sect. 2: Diseases/Disorders
8. Acne (Canine and Feline)
9. Anal Furunculosis/Perianal Fistula
10. Anal Sac Disorders
11. Atopic Disease
12. Autoimmune Blistering Diseases
13. Bacterial Pyoderma
14. Behavioral or Self-Injurious Dermatoses
15. Biting and Stinging Insects
16. Contact Dermatitis
17. Cutaneous Adverse Drug Reaction, Erythema Multiforme, Stevens-Johnson Syndrome, and Toxic Epidermal Necrolysis
18. Cutaneous Adverse Food Reactions
19. Demodicosis (Canine and Feline)
20. Dermatomyositis, Canine Familial
21. Dermatophytosis
22. Endocrinopathies, Atypical
23. Eosinophilic Disease (Granuloma) Complex
24. Epitheliotropic (Cutaneous) Lymphoma
25. Histiocytic Proliferative Disorders
26. Hyperadrenocorticism, Canine
27. Hyperadrenocorticism, Feline Skin Fragility Syndrome
28. Hypothyroidism
29. Keratinization (Cornification) Disorders
30. Leishmaniasis: Protozoan Dermatitis
31. Lupus Erythematosus
32. Malassezia Dermatitis
33. Mast Cell Tumors
34. Mycobacterial Infections
35. Mycoses, Deep
36. Nocardiosis and Actinomycosis
37. Otitis Externa, Media, and Interna
38. Panniculitis
39. Photodermatoses
40. Pododermatitis and Claw Disorders
41. Pre- and Paraneoplastic Syndromes
42. Sarcoptid Mites
43. Sebaceous Adenitis, Granulomatous
44. Sporotrichosis
45. Superficial Necrolytic Dermatitis
46. Tumors, Common Skin and Hair Follicle
47. Uveodermatologic Syndrome
48. Vasculitis
49. Viral Dermatoses
50. Zoonosis 727-730
A. Canine Genodermatoses
B. Drug Formulary.

Summary: This book provides a practical, comprehensive, state-of-the-art review of bladder cancer. A valuable resource for anyone with an interest in urothelial tumors, this text brings together a multidisciplinary team of experts who have distilled their vast years of experience and knowledge into a concise, easy to digest format. Topics covered range from importance of a pattern recognition in diagnosis and pathologic evaluation to How I do it? tips on patient selection for appropriate therapies such as chemotherapy, immunotherapy, surgery and radiation. Bridging the gap between a traditional textbook and hands-on experience, this book provides a practical guide to managing day-to-day issues and challenges and brings an algorithmic approach to avoid common pitfalls. Bladder Cancer: A Practical Guide provides a concise yet comprehensive summary of the current status of the field of bladder cancer treatment, guiding patient management and stimulating investigative efforts.

Contents:
Section 1: Patient Evaluation
Screening
Evaluation for Signs and Symptoms
Cystoscopy Inc
Using Urine Markers
Risk Stratification
Assessment/Management of Frailty
Section 2: TURBT (Tumor Resection)
Indications
Patient Preparation
Surgical Technique
Peri-operative Care
Management of Common Complications
Pathologist Assessment and Report
Oncologic Monitoring
Section 3: Adjvuant Intravesical Therapy
Introduction: Choice of Therapy
BCG
Chemo
Device Assisted
Intravesical Salvage Therapy
Section 4: Radical Cystectomy
Indications
Patient Preparation
Surgical Technique
Peri-operative Care
Management of Common Complications
Pathologist Assessment and Report
Oncologic Monitoring
Section 5: Urinary Diversion
Incontinent
Continent Cutaneous
Orthotopic Neobladder
Section 6: Peri-operative Chemotherapy
Neoadjuvant
Adjuvant
Section 7: Trimodal Therapy (Radiation)
Indications
Patient Preparation
Concomitant Chemo
External Beam Radiation
Management of Recurrence
Section 8: Systemic Therapy for Advanced Bladder Cancer
Chemotherapy
Immunotherapy
Novel Therapies
Section 9: Managing Variant Histology
Squamous/Glandular Differentiation
Micropapillary
Sarcomatoid
Small Cell/Neuroendocrine
Other
Squamous
Adenocarcinoma
Section 10: Clinical Trials in Bladder Cancer: Practical Pearls
Bladder Cancer Disease States
NMIBC
Metastatic.

Summary: Bladder Dysfunction in the Adult: The Basis for Clinical Management succinctly describes all that the healthcare professional needs to know when treating lower urinary tract symptoms. The book describes how to assess and treat every group of patients likely to be affected with bladder problems, and the underlying mechanisms responsible. Women with stress incontinence, men with enlarged prostates, people with neurological disease and the elderly are all discussed in particular detail. For all professionals treating or learning to treat patients with urinary storage or voiding problems, the concise presentation and thorough coverage provides treatment recommendations and clear explanations. Authored by recognized experts in their respective fields, Bladder Dysfunction in the Adult: The Basis for Clinical Management is a comprehensive resource that allows the reader to develop the knowledge, understanding, and confidence to deal with the many clinical challenges of bladder dysfunction.

Contents:
Relevant Anatomy Physiology and Pharmacology
Normal and Abnormal Function: An Overview
The Impact of Neurologic Insult on the Lower Urinary Tract
Dysfunction in Anatomic Outlet Obstruction in Men
Outlet Obstruction in Women
Bladder Pain Syndrome
Other Varieties of Dysfunction
Evaluation: History and Physical Examination; Imaging; Endoscopy
Urodynamics
Special Tests
Behavioral Therapy
Urinary Catheters and Other Devices
Current Pharmacologic Treatment of Lower Urinary Tract Syndromes
Electrical Stimulation and Neuromodulation
Surgery for Bladder Outlet Obstruction in the Male
Surgery for Stress Urinary Incontinence and Pelvic Organ Prolapse
Surgery for Neuropathic Bladder Dysfunction
Urinary Diversion
Tissue Engineering for Neurogenic Bladder
Considerations in Older People
Adolescent Urology and Transitional Care
The Psychological Impact of Lower Urinary Dysfunction.

Contents:
Alpha-1 antitrypsin deficiency
Serpins and serpinopathies
Alpha-1 antitrypsin biology
Alpha-1 antitrypsin gene, genetic heritage, phenotypes, and genotypes
Alpha-1 antitrypsin deficiency
Alpha-1 antitrypsin deficiency
Genetic epidemiology
Laboratory diagnosis
Clinical diagnosis
Liver disease associated with Alpha-1 antitrypsin deficiency
Respiratory manifestations of the Alpha-1 antitrypsin deficiency
Other diseases associated with Alpha-1 antitrypsin deficiency
Clinical management and treatment of lung disease
Registries and patients' associations
Current research and future perspectives.

Summary: Blast is an important foliar disease that infects the majority of cereal crops like rice, finger millet, pearl millet, foxtail millet and wheat, and thus results in a huge economic impact. The pathogen is responsible for causing epidemics in many crops and commonly shifts to new hosts. Magnaporthe spp. is the most prominent cause of blast disease on a broad host range of grasses including rice as well as other species of Poaceae family. To date, 137 members of Poaceae hosting this fungus have been described in fungal databases. This book provides information on all blast diseases of different cereal crops. The pathogen evolves quickly due to its high variability, and thus can quickly adapt to new cultivars and cause an epidemic in a given crop. Some of the topics covered here include historical perspectives, pathogen evolution, host range shift, cross-infectivity, and pathogen isolation, use of chemicals fungicides, genetics and genomics, and management of blast disease in different cereal crops with adoption of suitable methodologies. In the past two decades there have been significant developments in genomics and proteomics approaches and there has been substantial and rapid progress in the cloning and mapping of R genes for blast resistance, as well as in comparative genomics analysis for resolving delineation of Magnaporthe species that infect both cereals and grass species. Blast disease resistance follows a typical gene-for-gene hypothesis. Identification of new Avr genes and effector molecules from Magnaporthe spp. can be useful to understand the molecular mechanisms involved in the fast evolution of different strains of this fungal genus. Advances in these areas may help to reduce the occurrence of blast disease by the identification of potential R genes for effective deployment. Additionally, this book highlights the importance of blast disease that infects different cereal hosts in the context of climate change, and genomics approaches that may potentially help in understanding and applying new concepts and technologies that can make real impact in sustainable management of blast disease in different cereal crops.

Contents:
Preface
Blast Disease: Historical Importance, Its Distribution, and Host Infectivity Across Cereal Crops
Recent Advances in Blast Rice Disease
The Blast-A Major Malady in Neutricereals in Southeast Asia
Utilizing Host-Plant Resistance to Combat Blast Disease in Rice
Microconidia: Understanding Its Role in the Rice Blast Fungus Magnaporthe oryzae
Finger Millet Blast Pathogen Diversity and Management in Uttarakhand
Finger Millet Blast (Magnaporthe grisea): Current Scenario and Its Integrated Disease
Advances in Genetics, Genomics for Management of Blast Diseases in Cereal Crops
Wheat Blast Management: Prospects and Retrospective
Scenario of Blast Diseases in the Eastern Region of India
Chemicals in the Management of Blast Disease of Rice
Magnaporthe Genome: Lessons Learnt and the Way Forward
Bibliography
Index.

Contents:
Part 1. Basic Science and Engineering
1. The fundamentals of blast physics
2. Biomechanics in blast
3. Behaviour of materials
4. Blast Loading of Cells
5. Biological Tissue Response
Part 2. Weapon Effects and the Human
6. Blast Injury Mechanism
Section 3. Principles of Investigating and Modelling Blast and Blast Mitigation
7. The examination of post-blast scenes
8. Clinical Forensic Investigation of the 2005 London Suicide Bombings
9. Modelling the blast environment and relating this to clinical injury- Experience from the 7/7 Inquest
10. The mortality review panel: a report on the deaths on operations of UK Service personnel 2002-2013
11. Physical Models- Tissue Simulants.-12. Physical Models- Organ models for primary blast
13. In Vivo Models of blast injury
14. Modelling Blast brain injury
15. Military wound ballistics base study: Development of a Skull/Brain Model
16. Surrogates of human injury
17. Computational methods in continuum mechanics
18. Energised fragments: bullets and fragment simulating projectiles
Part 4. Applications of blast injury research: Solving clinical problems
19. Coagulopathy and inflammation: an overview of blast effects
20. Foot and Ankle Blast Injuries
21. Traumatic Amputation
22. Testing and development of mitigation systems for tertiary blast
23. Pelvic blast injury
24. Behind Armour blunt trauma (BABT)
25. Blast Injury to the Spine
26. Primary Blast Lung Injury
27. Regional effec ts of explosive devices: The neck
28. Optimising the anatomical coverage provided by military body Armour systems
29. Blast injuries of the Eye
30. Hearing damage through blast
31. Peripheral Nerve Injuries.

Summary: This heavily revised second edition provides a comprehensive multi-disciplinary resource on blast injuries. It features detailed information on the basic science, engineering, and medicine associated with blast injuries. Clear, easy to understand descriptions of the basic science are accompanied by case studies of a variety of clinical problems including heterotopic ossification, hearing damage, and traumatic brain injury, enabling the reader to develop a deep understanding of how to appropriately apply the relevant science into their clinical practice. The use of prosthetics, orthotics and osseointegration in rehabilitation is also covered. Blast Injury Science and Engineering: A Guide for Clinicians and Researchers is a valuable interdisciplinary text primarily focused towards clinical medical professionals and trainees seeking to develop a thorough understanding of injury mechanisms, and the latest treatment techniques. In addition, this resource is of use to individuals in other fields whose work centres around blast injury science such as injury mitigation researchers, military scientists and engineers.

Contents:
Preface: A history of blast injury science and engineering
Part I Basic science and engineering
Part II Weapons effects and forensics
Part III Clinical problems
Part IV Modelling blast and blast mitigation
Part V Application and innovation
Part VI Rehabilitation. .

Summary: Since the publication of the 1/e in 1977, Blaustein's Pathology of the Female Genital Tract has consolidated its position as the leading textbook of gynecological pathology. An essential reference for all pathologists and residents, this thoroughly updated Seventh Edition includes more than 1400 illustrations in color, informative tables and 22 revised chapters written by internationally recognized experts. Discussion of each specific entity is organized to include general information, etiology, and epidemiology followed by clinical features, pathologic findings, differential diagnosis, clinical behavior, and treatment. This clear organization is applied throughout the book and allows the reader to quickly access key information in every chapter. Blaustein's Pathology of the Female Genital Tract remains the gold-standard reference for practicing pathologists and trainees, as well as for obstetric/gynecology practitioners and residents.

Contents:
Benign Diseases of the Vulva
Premalignant and Malignant Tumors of the Vulva
Diseases of the Vagina
Benign Diseases of the Cervix
Precancerous Lesions of the Cervix
Carcinoma and Other Tumors of the Cervix
Benign Diseases of the Endometrium
Precursor Lesions of Endometrial Carcinoma
Endometrial Carcinoma
Mesenchymal Tumors of the Uterus
Diseases of the Fallopian Tube and Paratubal Region
Nonneoplastic Lesions of the Ovary
Diseases of the Peritoneum
Surface Epithelial Tumors of the Ovary
Sex Cord-Stromal, Steroid Cell, and Other Ovarian Tumors with Endocrine, Paraendocrine and Paraneoplastic Manifestations
Germ Cell Tumors of the Ovary
Nonspecific Tumors of the Ovary Including Mesenchymal Tumors
Metastatic Tumors of the Ovary
Diseases of the Placenta
Gestational Trophoblastic Tumors and Related Tumor-like Lesions
Hematologic Neoplasms and Selected Tumor-Like Lesions
Soft Tissue Lesions Involving Female Reproductive Organs. /p>.

Summary: This edited volume is about how unprejudiced approaches to real human cognition can improve the design of AI. It covers many aspects of human cognition and across 12 chapters the reader can explore multiple approaches about the complexities of human cognitive skills and reasoning, always guided by experts from different but complimentary academic fields. A central concept is explained: blended cognition, the natural skill of human beings for combining constantly different heuristics during their several task-solving activities. Something that was sometimes observed like a problem as "bad reasoning", is now the central key for the understanding of the richness, adaptability and creativity of human cognition. The topic of this book connects in a significant way with the disciplines of psychology, neurology, anthropology, philosophy, logics, engineering, logics, and AI. In a nutshell: understanding better humans for designing better machines. Any person with interests on natural and artificial reasoning should read this book as a primary source of inspiration and a way to achieve a critical thinking on these topics.

Contents:
Preface Blended Cognition Vincent C. Müller & Jordi VallverdúPhilosophy 1. Blended cognition. The robotic challenge Jordi Vallverdú2. Manipulative Abduction, External Semiotic Anchors, and Blended Cognition Lorenzo Magnani3. Practical Reasoning in the Deliberations of an Intelligent Autonomous Agent Douglas Walton4. Blended Automation: The Language-Game of Psychoanalytic Automatism and Cybernetic Automata Vassilis GalanosEngineering 5. Can our Robots rely on an Emotionally Charged Vision-for- Action? An Embodied Model for Neurorobotics Gabriele Ferretti & Eris Chinellato6. Modeling psycho-emotional states via neurosimulation of monoamine neuro-Transmitters Max Talanov, Alexey Leukhin, Fail Gafarov & Jordi Vallverdú7. Towards Conversation Envisioning for Cognitive Robots Maryam Sadat Mirzaei, Qiang Zhang, Stef van der Struijk & Toyoaki NishidaPsychology 8. The blending of human and autonomous-machine cognition Robert Earl Patterson and Robert G. Eggleston (USAF)9. Heuristics of Numerical Choice in Economic Contexts Kay-Yut Chen & Daniel S. Levine Anthropology 10. Towards autonomous artificial agents? Proposal for a naturalistic activity-based model of (artificial) life
Corentin Chanet & David Eubelen Logics 11. Toward a Logic of Everyday Reasoning Pei Wang Index.

Summary: This book is a comprehensive overview of blepharitis that covers various the definitions and types of blepharitis. It meets the market need for a comparable book on this topic that recognizes blepharitis as being both a common diagnosis and a challenging condition to treat. Concise and unique, chapters are clinically focused, provide an equal focus on surgical management as well as on medical management of this condition. The book concludes with a look at future directions in the field as they pertain to the diagnosis, clinical treatment, and management of blepharitis. Blepharitis is an invaluable reference written specifically for comprehensive ophthalmologists, cornea and external disease specialists, residents, fellows, and optometrists.

Contents:
1. Anterior Blepharitis
2. Posterior Blepharitis
3. Local and Systemic Associations
4. Diagnostic Tools
5. Sebaceous Carcinoma: Masquerade Syndrome
6. Medical Management of Blepharitis
7. Procedural Management
8. Blepharitis: Future Directions.

Summary: "Antonio Marez is six years old when Ultima comes to stay with his family in New Mexico. Ultima is a curandera, one who cures with herbs and magic. Under her wise wing, Tony will probe the family ties that bind and rend him as he discovers himself in the magical secrets of the pagan past-a mythic legacy as palpable as the Catholicism of Latin America. And at each life turn, there is Ultima, who delivered Tony into the world . . . and will nurture the birth of his soul."-- Provided by publisher.

Summary: "Infection control and concerns about spread of disease date back to ancient times: early Greek, Roman, and Biblical texts outline strict dietary guidelines, quarantines for people with leprosy, and instructions for returning soldiers to burn equipment and clothes. Aristotle instructed Alexander the Great to require his armies to boil their drinking water. Today, concerns about drug resistance (eg: farmed fish as a source of antibiotic resistance; drug-resistant tuberculosis; drug-resistant bacteria on endoscopes) dominate news headlines and command serious research and industry investment.Seymour S Block's Disinfection, Sterilization, and Preservation was first published in 1968, and is considered to be the gold standard for those involved with technologies or products dependent on preservatives, sterilization or disinfection. The various sections and detailed chapters of the book include introductions, fundamental principles of activity, chemical types of disinfectants/sterilants, controls of particular types of microorganisms, physical disinfection/sterilization technologies, medical & health related applications, test methodologies, and miscellaneous other topics. The last edition was published in 2000, and since that time much has changed in our understanding of the risks, the technologies available, and the regulatory environments in the practical applications of these technologies. Additionally, focus has somewhat shifted from "how to kill it" to "how to prevent it" A new edition, discussing new understandings of microbes and how to manage them through disinfection and prevention is necessary. Dr. Block has passed away, but he has several colleagues and previous contributors who are desirous of carrying the mantle of this important title. The proposed editors are well respected in the area, with backgrounds in the antimicrobial control of infection risks; one of the editors has a greater background in the medical application of technologies and the other for industrial applications, offering a nice balance"-- Provided by publisher.

Summary: This is a highly informative and carefully presented book for trainees and postgraduate students of anaesthesiology as well as practicing clinicians. This book aims to help them in selecting and implementing the most suitable regional block in each clinical scenario and successfully use the techniques of ultrasound-guided regional anaesthesia (USRA) in their practice. This book covers basics of ultrasound imaging, anatomical aspects and techniques of all nerve blocks that are commonly used in clinical practice in a lucid and illustrated presentation. Regional anaesthesia can be a safe alternative to general anaesthesia. When combined with general anaesthesia, it can provide excellent postoperative analgesia too. With the advent of ultrasound, the scope, safety and reliability of regional anaesthesia has expanded manifold. However, there is a lack of formal clinical training in regional anaesthesia in most of the anaesthesia postgraduate curricula and this book intends to bridge this gap. The book serves as a useful resource to the anaesthetist; trainee or practitioner who wants to master the nerve blocks.

Contents:
Basics of ultrasound guided regional anaesthesia
Blocks in upper limbs
Blocks for lower limbs
Truncal blocks
Neuraxial blocks
Pediatric Regional Anaesthesia
Recent advances
Safety and ergonomics and education.

Summary: This updated and expanded edition developed by the Blood and Marrow Stem Cell Transplant team at Oregon Health & Science University Knight Cancer Institute features the latest medical management guidelines and standards of care for hematopoietic stem cell transplant and cellular therapy patients. Spanning the timeline from the initial consultation throughout the transplant process, this handbook begins by providing a general overview of stem cell transplantation and goes on to outline disease-specific indications for stem cell transplantation. It then focuses on transplant complications and ongoing care, and finally explores cellular therapies for hematologic malignancies. Comprehensive and easy-to-use, Blood and Marrow Transplant Handbook: Comprehensive Guide for Patient Care, Third Edition presents a multidisciplinary approach to information for physicians and advanced practice medical providers as well as residents, fellows, and other trainees who care for patients who undergo transplant and immune effector cell therapy.

Contents:
Introduction / Bipin N. Savani
Overview : transplant data and increasing numbers of long-term survivors / Jakob R. Passweg and Helen Baldomero
Long-term transplant clinic setup / Andre Tichelli ... [et al.]
Late effects after allogeneic hematopoietic stem cell transplantation / Sairah Ahmed and Yago Nieto
Late effects after autologous hematopoietic stem cell transplantation / Sairah Ahmed and Yago Nieto
Graft-versus-host disease and late effects after hematopoetic stem cell transplantation / Gerard Socie
Prominent role of allied health professionals (nurse practitioners, physician assistants, others) in long term follow-up after hematopoietic stem cell transplantation / Catherine E. Lucid
Screening and prevention guidelines for hematopoietic cell transplant survivors / Navneet S. Majhail and j. Douglas Rizzo
Secondary malignancies : prevalence, screening, prevention, and management guidelines / Paolo F. Caimi and Hillard M. Lazarus
Cutaneous chronic graft-versus-host disease / Attilio Olivieri ... [et al.]
Anti-infective prophylaxis, immunization and prevention of recurrent infectious complications in long-term survivors / John P. Galvin and Jayesh Mehta
Seasonal virus infections : prevention and management guidelines / Gaurav Trikha and John R. Wingard
Exposure to family members : infections and recent live vaccinations / Brian G. Engelhardt and James E. Crowe, Jr.
Late pulmonary complications after allogeneic hematopietic stem cell transplantation : bronchiolitis obliterans syndrome (BOS) and organizing pneumonia (OP) / Lee Gazourian ... [et al.]
Post-transplantation bone disease : prevalence, monitoring, prevention and management guidelines / Andre Tichelli and Alicia Rovo
Ocular complications : prevalence, monitoring, prevention, and management guidelines / Andre Tichelli and Alicia Rovo
Oral complications in hematopoietic stem cell transplantation survivors : monitoring and management / Andrea L. Utz and Shubhada Jagasia
Fertility issues, contraception, and pregnancy outcome in long-term survivors / Alicia Rovo ... [et al.]
Follow-up of children after hematopoietic stem cell transplantation : growth and development / Kristina K. Hardy ... [et al.]
Posttransplant diabetes mellitus : monitoring, prevention, and management guidelines / Prathima Jasti, Shichun Bao, and Shubhada Jagasia
Thyroid disease : monitoring and mangement guidelines / M. Kathleen Figaro ... [et al.]
Special issues related to female long-term survivors / Melissa A. Merideth ... [et al.]
Cardiac and vascular complications in long-term survivors after hematopoietic stem cell transplantation / Alicia Rovo and Andre Tichelli
Hyperlipidemia : prevalence, monitoring, management, interactions with immunosuppressive agents and follow-up / Dara L. Eckerle Mize, Shubhada Jagasia, and Jeffrey B. Boord
Hypertension management in long-term survivors / Imad Abboud
Gastrointestinal complications of hematopoietic cell transplantation / Preet Bagi ... [et al.]
Hepatic complications of hematopoietic stem cell transplantation / Niharika Samala ... [et al.]
Monitoring and management of hepatitis B, hepatitis C, and HIV infection before and after transplantation / Keith Luckett and Stephen Dummer
Prevention and management of renal complications in long-term survivors / Michael Dickenmann and Joerg P. Halter
Immunosuppressive agents and monitoring in long-term survivors / Paul Shaughnessy and Helen Leather
Nutritional assessments and nutritional supplementation for long-term transplant survivors : multivitamins, vitamin D, Calcium, antioxidants, and minerals / Lauren Zatarain ... [et al.]
Daily routines and guidelines : driving, infection isolation, masks, food/diet, activities, exercise, pets, sun exposures, and others / Angela M. Woods
Caregivers of long-term survivors / Elizabeth Wulff-Burchfield
Health-related quality of life in adult and pediatric survivors of hematopoietic stem cell transplantation / Margaret Bevans and Lori Wiener
Prevalent psychosocial adjustment issues nd solutions : lifestyle and social challenges / Katrina M. Stokes
Patient's perspective : concepts of long-term survivor support groups and their roles / Michael W. Brown
Appendix 1 NMDP/Be the match posttransplant guidelines resources / Darlene Haven
Appendix 2 Long-term follow-up calendar / Andre Tichelli ... [et al.]
Appendix 3 Commonly used transplant-related medications in long-term survivors / Melissa Logue.

Summary: "Hematopoietic cell transplantation (HCT) provides curative therapy for a variety of diseases. Over the past several decades, significant advances have been made in the field of HCT and now HCT has become an integral part of treatment modality for a variety of hematologic malignancies and some nonmalignant diseases. HCT remains an important treatment option for a wide variety of hematologic and nonhematologic disorders, despite recent advances in the field of immunologic therapies. Factors driving this growth include expanded disease indications, greater donor options (expanding unrelated donor registries and haploidentical HCT), and accommodation of older and less fit recipients. The development of less toxic pretransplant conditioning regimens, more effective prophylaxis of graft-versus-host disease (GVHD), improved infection control, and other advances in transplant technology have resulted in a rapidly growing number of transplant recipients surviving long-term free of the disease for which they were transplanted. The changes over decades in the transplant recipient population and in the practice of HCT will have almost inevitably altered the composition of the long-term survivor population over time. Apart from an increasingly older transplant recipient cohort, the pattern of transplant indications has shifted from the 1990s when chronic myeloid leukemia made up a significant proportion of allo-HCT indications. Changes in cell source, donor types, conditioning regimens, GVHD prophylaxis, and supportive care have all occurred, with ongoing reductions in both relapse and non-relapse mortality (NRM) have been demonstrated"-- Provided by publisher.

Summary: Within the central nervous system (CNS) the constantly changing blood stream is separated from the CNS parenchyma by the blood brain barrier (BBB) restricting passage to selected immune cells. Under pathological conditions, however, viruses, bacteria, parasites and autoaggressive immune cells can penetrate the barrier and contribute to CNS inflammation. The BBB actively contributes to neuroinflammation by presentation of chemokines, expression of cell adhesion molecules and alteration of barrier properties. As such, understanding the role of the BBB under healthy and pathological conditions is essential for the development of new drugs to efficiently combat inflammatory diseases of the CNS. This book presents a comprehensive collection of reviews that focus on the role of the BBB. Experts in the field share their insight on structural, topological and functional properties of the BBB. They elaborate on pathophysiological changes of the inflamed BBB such as permeability, transporter proteins and alterations in microRNAs and cytokine profile. Additional chapters on multiple sclerosis and bacterial meningitis provide in depth information on significant neuroinflammatory diseases. The selection is complemented by a review on the current understanding of the BBB as signaling hub in tumor pathogenesis in the brain.

Contents:
General Introduction to Barrier Mechanisms in the Central Nervous System
Topological Aspects of the Blood-brain and Blood cerebrospinal Fluid Barriers and their Relevance in Inflammation Research
The Contribution of the Extracellular Matrix to the BBB in Steady State and Inflammatory Conditions
Pathophysiology of the Bloodbrain Barrier in Neuroinflammatory Diseases
Leakage at Blood-neural Barriers
Blood-Brain Barrier Transporters and Neuroinflammation: Partners in Neuroprotection and in Pathology
MicroRNAs in Brain Endothelium and Inflammation
Blood-Brain Barrier Dysfunction during Central Nervous System Autoimmune Diseases
Pathways Across the Blood Brain Barrier
Neuroinflammation in Bacterial Meningitis
Blood Vessels in the Brain: a Signaling Hub in Brain Tumor Inflammation.

Contents:
Part I. Blood Pressure: Basic Concepts of Steady and Pulsatile Arterial Hemodynamics
1. Arterial Stiffness, Wave Reflection, Wave Amplification: Basic Concepts, Principles of Measurement and Analysis in Humans / Michael F. O'Rourke, Caroline O'Brien, and Thomas Weber
2. Large Arteries, Microcirculation, and Mechanisms of Hypertension / Harry A.J. Struijker-Boudier
3. Direct Measurement of Local Arterial Stiffness and Pulse Pressure / Luc M. Van Bortel, Tine De Backer, and Patrick Segers --4. Ventricular-Arterial Coupling and Mechanism of Wave Reflections / Julio A. Chirinos and Patrick Segers
5. Determination of Systemic and Regional Arterial Structure and Function / Pierre Boutouyrie, Laurent Macron, Elie Mousseaux, and Stéphane Laurent
6. Animal Models for Studies of Arterial Stiffness / Patrick Lacolley, Simon N. Thornton, and Yvonnick Bezie
7. Elastin, Calcium and Age-Related Stiffening of the Arterial Wall / Jeffrey Atkinson
8. Genetic and Cellular Aspects of Arterial Stiffness / Athanase Benetos, Abraham Aviv, Patrick Lacolley, Michel E. Safar, and Véronique Regnault
Part II. Blood Pressure and Sodium Balance: Pathophysiological Mechanisms and Cardiovascular Risk
9. Mechanical Stress and the Arterial Wall / Ernesto L. Schiffrin, Alain Tedgui, and Stephanie Lehoux
10. Pulsatile Stress, Arterial Stiffness, and Endothelial Function / Robinson Joannidès, Jérémy Bellien, and Christian Thuillez
11. Hypoxia, Arterial Blood Pressure, and Microcirculation / Jean-Jacques Mourad, Jean-Sébastien Silvestre, and Bernard I. Lévy
12. The Reality of Aging Viewed from the Arterial Wall / Majd AlGhatrif and Edward G. Lakatta
13. Emerging Aspects of Angiotensin Biology and Their Potential Role in the Vasculature / Richard N. Re and Julia L. Cook
14. Arterial Stiffness and the Sympathetic Nervous System / Gianfranco Parati and Paolo Salvi
15. Oxidative Stress and Hypertension / Jing Wu and David G. Harrison
16. Heart Failure with Preserved Ejection Fraction / Scott L. Hummel
17. Structural Alterations in Arterial Stiffness: Role of Arterial Fibrosis / Javier Díez
18. Salt and Multiorgan Damage in Hypertension: Vascular Stiffening and Cardiorenal Structural Dysfunction Responses / Edward D. Frohlich
19. Preventive Lessons from Hypertension and Myocardial Infarction: Treating Asymptomatic Individuals to Lower the Risk for Subsequent Cardiovascular Events / Marc A. Pfeffer
Part III. Hypertension: Evaluation of Cardiovascular Risk and Organ Damage
20. Value of Brachial and Central Blood Pressure for Predicting Cardiovascular Events / Stanley S. Franklin, Carmel M. McEniery, John R. Cockcroft, and Ian B. Wilkinson
21. Predictive Value of Arterial Stiffness for Cardiovascular Events / Stéphane Laurent, Pierre Boutouyrie, and Francesco Mattace Raso
22. Heart Rate, Synchrony and Arterial Hemodynamics / Alberto P. Avolio, Mark Butlin, and Isabella Tan
23. Pulse Pressure Amplification and Arterial Stiffness in Middle Age / Alberto P. Avolio, Mark Butlin, and Athanase D. Protogerou
24. Arterial Stiffness, Central Blood Pressure and Cardiac Remodelling: From Cardiac Hypertrophy to Heart Failure / Mary J. Roman and Richard B. Devereux
25. The Relationship Between Aortic Stiffness, Microvascular Disease in the Brain and Cognitive Decline: Insights into the Emerging Epidemic of Alzheimer's Disease / Angelo Scuteri, Jonathan Stone, and Michael F. O'Rourke
26. Arterial Stiffness and Risk in Various Cardiovascular Diseases / Charalambos Vlachopoulos, Dimitrios Terentes- Printzios, Kenji Takazawa, and Christodoulos Stefanadis
27. Large Artery Remodeling and Chronic Kidney Disease / Marie Briet, Michel Delahousse, Gérard London, Stéphane Laurent, and Pierre Boutouyrie
28. Arterial Changes in Renal Transplantation / Sola Aoun Bahous, Serge Korjian, Yazan Daaboul, Jacques Blacher, and Michel E. Safar
29. Arterial Stiffness, Central Blood Pressure and Coronary Heart Disease / Piotr Jankowski, Jacques Blacher, and Thomas Weber
Part IV. Clinical Involvement: Role of Age, Sex, Inflammatory and Metabolic Alterations
30. Modifications of Blood Pressure Profiles in the Very Old: Role of Frailty and Comorbidities / Athanase Benetos, Sylvie Gautier, and Michel E. Safar
31. Arterial Stiffness and Amplification in the Very Old / Athanase Benetos, Ghassan Watfa, Paolo Salvi, and Patrick Lacolley
32. Hypertension in Men and Women: Is It Different? / Harold Smulyan and Bruno Pannier
33. Obesity, Metabolic Syndrome, Diabetes and Smoking / Isabel Ferreira, Roel J.J. van de Laar, and Coen D.A. Stehouwer
34. Glucose, Insulin and Potential Strategies of Vascular Stiffening / Guanghong Jia, Annayya R. Aroor, Gerald A. Meininger, and James R. Sowers
35. Arterial Stiffness in Chronic Inflammation / Kaisa M. Mäki-Petäjä, Carmel M. McEniery, Stanley S. Franklin, and Ian B. Wilkinson
Part V. Stratifications of Cardiovascular Risk and Therapeutic Consequences on Arterial Stiffness and Wave Reflections
36. Outcome-Driven Thresholds for Pulse Pressure on Office and Out-of-the-Office Blood Pressure Measurement / Yumei Gu, Lucas S. Aparicio, Yanping Liu, Kei Asayama, Tine W. Hansen, Teemu J. Niiranen, José Boggia, Lutgarde Thijs, and Jan A. Staessen
37. Properties of Central Arteries in Populations of Different Ethnicity: Ethnicity and Central Arteries / Augustine Nonso Odili, Yumei Gu, and Jan A. Staessen
38. Changing Concepts on the Role of Blood Pressure Reduction in Stroke Prevention with the Focus on β-Blocking Agents / Ji-Guang Wang, Feng-Hua Ding, Li-Hua Li, and Yan Li
39. Decreasing Arterial Stiffness and/or Wave Reflections Independently of Mean Arterial Pressure: Effect of Antihypertensive Drugs (Part 1) / Hélène Beaussier, Stéphane Laurent, and Pierre Boutouyrie
40. Decreasing Arterial Stiffness and/or Wave Reflections Independently of Mean Arterial Pressure: Effect of Non-antihypertensive Drugs (Part 2) / Hélène Beaussier, Stéphane Laurent, and Pierre Boutouyrie
41. Blood Pressure Variability: Measurements, Influential Factors, Prognosis and Therapy / Yi Zhang, Davide Agnoletti, Alexandra Yannoutsos, Michel E. Safar, and Jacques Blacher
42. Nitrate: The Ideal Drug Action for Isolated Systolic Hypertension in Elderly? / Xiong J. Jiang and Michael F. O'Rourke
43. De-stiffening Strategy, Sodium Balance, and Blockade of the Renin-Angiotensin System / Athanase D. Protogerou, Michel E. Safar, Gerard E. Plante, and Jacques Blacher
44. Long-Term Effects of Calcium Channel Blockers on Central and Peripheral Arteries / Yoshio Matsui and Michael F. O'Rourke
45. Exercise Training for the Modification of Arterial Stiffness and Wave Reflections / Julian W. Sacre and Bronwyn A. Kingwell.

Summary: This book provides an in-depth and up-to-date review of the association between blood pressure disorders and diabetes mellitus. In addition, it discusses the specific role of hemodynamic alterations on the vasculature of various target organs (the retina, kidney, brain, and gravid uterus), topics that are infrequently considered and or acknowledged by clinicians. Covering all aspects of the interaction between metabolic and hemodynamic factors, the book presents the diverse perspectives of the contributing authors and extensive discussions of issues including diabetic kidney disease, diabetic hypertensive phenotypes and postural hypotension.

Contents:
I Introduction
1 Coexistence of Diabetes Mellitus and Hypertension
II Epidemiological Aspects
2 BP disorders in diabetic children/adolescents
3 Hypertension and Type 2 Diabetes Mellitus
4 BP Disorders in Gestational Diabetes (Hypertension / Preeclampsia)
III Screening and Diagnostic Approaches in Diabetic Hypertensive Patients
5 Office / Out-of-Office Blood Pressure Measurements
6 Laboratory Indices / Bioimaging
IV Pathophysiological Mechanisms
7 Genetics
8 Insulin and BP relationships
9 Mechanisms of Diabetic Nephropathy in Experimental Animals
10 Molecular Alterations in Diabetic Chronic Kidney Disease
V Target Organ Damage in Diabetic Hypertensive Patient
11 Endothelial Dysfunction / Arterial Stiffness
12 Heart in Diabetic Hypertensive Patients
13 Cerebrovascular Structural Alterations
14 Diabetic Nephropathy in Type 1 Diabetes Mellitus
15 Diabetic Chronic Kidney Disease in Type 2 Diabetes Mellitus (Albuminuric/ Nonalbuminuric)
16 Diabetic Retinopathy
VI Strategies for Blood Pressure Control
17 Target Blood Pressure Values / Choice of Antihypertensive Drug Classes
VII Benefits of Antihypertensive Treatment
18 Lifestyle modification
19 Blood Pressure Thresholds for Initiation of Drug Treatment / and Effect of Blood Pressure Reduction on Target Organs
VIII Antihypertensive Drugs and Diabetes Mellitus: Special Problems
20 Adverse reactions associated with RAAS Blockers
21 Insulin Resistance and New Onset Diabetes Mellitus
22 Management of Hypertensive Diabetic Patient during Ramadan Fasting
IX Other Therapeutic Modalities
23 Control of Blood Glucose and Cardiovascular Risk Profile
X Hypotensive Disorders
24 Supine / Postural Hypotensive Blood Pressure Levels.

Summary: This book functions as a comprehensive and authoritative reference book in blood transfusion and blood substitutes. It is a collection of the latest developments and the newest investigations, and individual chapters are written by world experts in the arena. The book begins with a historical review on the practice of transfusions as well as the components and physiology of blood. The following chapters cover various topics, including platelet substitutes, hemoglobin-based oxygen carriers, perfluorocarbon based oxygen carriers, and safety issues related to artificial hemoglobin. All chapters provide a bulleted highlights list to facilitate readers in mastering the main points of each individual chapter. Blood Substitutes and Oxygen Biotherapeutics is an invaluable reference book for perioperative care providers, hematologists, anesthesiologists, surgeons, obstetricians and gynecologists.

Contents:
ATP and Oxygen: the Energy Economy of the Cell
Physiological Functions of Blood
Hemoglobin: Physiology and Hemoglobinopathy
The Global Burden of Anemia
Blood Component Therapy: the History, Efficacy, and Adverse Effects in Clinical Practice
Allogeneic Blood Transfusion: Complications and Side Effects
The real-time effects of artificial blood substitutes on the microcirculation
Vascular endothelium and nitric oxide
A Brief History of Development of Nanobiotechnology-based Blood Substitutes
Classification of Blood Substitutes
Hemoglobin-based Oxygen Carriers
Complications of HBOCs including clinical safety issues
Free Hemoglobin Toxicity
Nanotechnology-based oxygen and drug carriers
Perfluorocarbon-based Oxygen Carriers
Platelet Substitutes
Plasma Substitutes
Novel nanobiotherapeutic based blood substitutes
Paradigm Shift
Hemoglobin-Based Blood Substitute
Hemoglobin vesicles as artificial red cells
Low Volume Resuscitation Agents in Prehospital Medicine
ErythroMer: Bio-Inspired Artificial Red Blood Cell
OxyVita-Erythrocruorin
HemAssist: History, clinical trials
Development of Recombinant Hemoglobin
Hemolink-PolyHeme
Safety and Tolerability Study -in Stable Adult Patients with Sickle Cell disease
Oxygent-Sanguinate
M101, the Hemoglobin from the Sea-Hemopure: clinical trials and current status
Perftoran: History-Oxycyte-Hemoximer
Transplantation
Hemorrhagic Shock: HBOCs in Trauma
Use of Oxygen
Regulatory Update.

Contents:
-- Changes in blood volume and plasma proteins after bleeding and immediate substitution with physiologic saline, dog plasma and dog albumin in the splenectomized dog / Å. Rieger
3. Changes in blood volume and plasma proteins after bleeding and immediate substitution with Macrodex. Rheomacrodex and Physiogel in the splenectomized dog / Å. Rieger
4. Importance of thoracic duct lymph in restitution of plasma volume and plasma proteins after bleeding and immediate substitution in the splenectomized dog / S
O. Liljedahl and Å. Rieger.

Summary: "This is the first book to argue in favor of paying people for their blood plasma. It does not merely argue that offering compensation to plasma donors is morally permissible. It argues that prohibiting donor compensation is morally wrong-and that it is morally wrong for all of the reasons that are offered against allowing donor compensation. Opponents of donor compensation claim that it will reduce the amount and quality of plasma obtained, exploit and coerce donors, and undermine social cohesion. James Stacey Taylor argues that empirical evidence demonstrates that compensating plasma donors greatly increases the amount of plasma obtained with no adverse effects on the quality of the pharmaceutical products that are manufactured from it. Prohibiting compensation thus harms patients by reducing their access to the medicines they need. He also argues that it is the prohibition of compensation-not its offer-that exploits donors, fails to respect the moral need to secure a person's authoritative consent to her treatment, and prevents donors from giving their informed consent to donate. Prohibiting compensation thus not only harms patients-it wrongs donors. Bloody Bioethics will appeal to researchers, advanced students, and medical professionals interested in bioethics, moral philosophy, and the moral limits of markets"-- Provided by publisher.

Summary: This book reviews the emerging role of blue laser as a new treatment modality. Laser surgery has revolutionized the treatment of patients with voice disorders. The choice of laser is based primarily on the characteristics of the laser such as wavelength, mode of delivery and spot size, and on the type of pathology that is being treated. Recently, a new laser with hybrid characteristics, namely cutting and hemostatic, has been introduced as the new generation of photoangiolytic lasers. This new laser--the blue laser with a wavelength of 445 nm--is gaining popularity as an alternative to the traditional KTP laser. The book begins with a review of lasers in laryngology, which is followed by a discussion of anesthesia considerations in office-based and OR-based laryngeal surgery. Subsequent chapters detail the surgical steps needed to be able to perform office-based blue laser procedures safely, including the mode of application and the use of adjunctive surgical procedures. These chapters present colored illustrations of various cases of laryngeal pathology before and after treatment. Video-recordings of surgeries performed in-office and in the operating room using the blue laser are included. Finally, the authors cover rare applications of blue laser therapy in laryngology. This is an ideal guide for otolaryngologists and laryngologists, as well as speech-language pathologists, phoniatricians and other voice therapists and trainers.

Contents:
1 Introduction
2 Anesthesia Considerations in Office-Based and OR-Based Laryngeal Surgery
3 Blue Laser Therapy of Vocal Fold Varices and Ectasias
4 Blue Laser Therapy of Exudative Lesions of the Vocal Folds
5 Blue Laser Therapy of Vocal Process Granuloma
6 Blue Laser Therapy of Recurrent Respiratory Papillomatosis
7 Blue Laser Therapy of Vocal Fold Leukoplakia
8 Blue Laser Therapy of Vocal Fold Scars
9 Blue Laser Therapy of Laryngeal Stenosis
10 Rare Applications of Blue Laser Therapy in Laryngology.

Summary: In 2011, Dr. Peter J. Hotez relocated to Houston to launch Baylor's National School of Tropical Medicine. He was shocked to discover that a number of neglected diseases often associated with developing countries were widespread in impoverished Texas communities. Despite the United States' economic prowess and first-world status, an estimated 12 million Americans living at the poverty level currently suffer from at least one neglected tropical disease, or NTD. Hotez concluded that the world's neglected diseases-which include tuberculosis, hookworm infection, lymphatic filariasis, Chagas disease, and leishmaniasis-are born first and foremost of extreme poverty. In this book, Hotez describes a new global paradigm known as "blue marble health," through which he asserts that poor people living in wealthy countries account for most of the world's poverty-related illness. By crafting public policy and relying on global partnerships to control or eliminate some of the world's worst poverty-related illnesses, Hotez believes, it is possible to eliminate life-threatening disease while at the same time creating unprecedented opportunities for science and diplomacy.

Contents:
A changing landscape in global health
The "other diseases": the neglected tropical diseases
Introducing blue marble health
East Asia : China, Indonesia, Japan, and South Korea
India
Sub-Saharan Africa : Nigeria and South Africa
Saudi Arabia and neighboring conflict zones of the Middle East and North African region
The Americas : Argentina, Brazil, and Mexico
Australia, Canada, European Union, Russian Federation, and Turkey
United States of America
The G20 : "a theory of justice"
A framework for science and vaccine diplomacy
Future directions.

Summary: This open access book is an original contribution to the knowledge on fishing and research associated with one of the most enigmatic fish of our seas: bluefin tuna, Thunnus thynnus (L.). Based on available evidence, it reconstructs the possible methods used to catch large spawners in the Strait of Gibraltar thousands of years ago and describes the much more recent overfishing that led to a great reduction in the catches of the trap fishery on the area and the disappearance of the northern European fisheries. It is the first book to relate the overfishing of juvenile fishes in certain areas to the decline of large spawners in other very distant areas, revealing one of the main underlying causes of this decline, which has remained a mystery to the fishing sector and scientists alike for over 50 years. This finding should serve to prevent similar cases from arising in the future.

Contents:
Introduction
Some characteristics of the bluefin tuna its geographical distribution, areas and fishing systems
The bluefin tuna catch in the Strait of Gibraltar, a review of its history
the present state of traps and fisheries research in the Strait of Gibraltar
Bluefin tuna fishing in the Bay of Biscay
Research related to bluefin tuna fishing in the Bay of Biscay
A publication that sheds light on the disappearance of the eastern Atlantic bluefin tuna spawner in the 1960s.

Summary: Blueprints Family Medicine provides a complete, yet succinct review of the key concepts and topics that students need to know for a four- to six-week family medicine clerkship. With its concise, well-organized format, it serves as an ideal rapid reference for day-to-day patient care as well as subject examinations and board review. Updates throughout reflect the most current treatment and management strategies. A new section covers the 25 drugs most commonly prescribed in the primary care setting. Case vignettes demonstrate clinical applications. 100 USMLE-style review questions, with full explanations, facilitate exam preparation. Key Points at the end of each chapter summarize important information. Clinical boxes highlight clinical manifestations, differential diagnoses, and treatment options. A helpful appendix provides easy access to evidence-based resources.

Contents:
Part I. Principles of family medicine
Elements of family medicine
Patient communication and coordination of care – Screening – Immunizations
Preventive care: 19 to 64 Years
Preoperative evaluation
Family violence: awareness and prevention
Part II. Common signs and symptoms
Allergies
Back pain
Chest pain – Constipation – Cough – Diarrhea
Dizziness/Vertigo – Fatigue
Headache – Heartburn – Hematuria
Jaundice in adults
Knee pain – Lymphadenopathy
Nausea and vomiting --Painful joints
Palpitations – Pharyngitis – Proteinuria
Red eye
Respiratory infections
Shortness of breath
Shoulder pain
Somatic symptom disorder – Swelling
Weight loss
Part III. Common medical conditions – Acne
Alcohol and substance abuse – Anemia – Anxiety – Asthma
Atopic dermatitis
Chronic obstructive pulmonary disease
Congestive heart failure – Depression
Diabetes Mellitus Type 2 – Diverticulitis
Human immunodeficiency virus
Hypertension – Hyperthyroidism – Hypothyroidism – Obesity
Oral health – Osteoporosis
Prostate disease
Sexually transmitted diseases
Skin infections
Tobacco abuse
Urinary Tract Infection – Urticaria
Part IV. Women’s health
Abnormal pap smear
Abnormal vaginal bleeding – Amenorrhea
Breast Masses
Contraception – Vaginitis
Part V. Maternity care -Preconception counseling and prenatal care
Common medical problems in pregnancy
Postpartum care
Part VI. Care for infants, children, and adolescents
Preventive care: newborn to 5 years
Preventive care: 5 to 12 years
Adolescent medicine
Common medical problems in children
Behavioral issues in children
Fever in children
Otitis media
Preparticipation evaluation
Part VII. Care for older adults
Preventive care: 65 years and older
Geriatric assessment
Common medical problems in older adults – Dementia
Urinary incontinence
Nursing home and end-of-life care
Part VIII. Common medications
Analgesics: nonsteroidal anti-inflammatory and opioid medications – Antibiotics
Cardiovascular medications
Endocrine medications
Gastrointestinal medications
Psychiatric medications
Other medications.

Summary: One of the best selling and most highly regarded volumes in the Blueprints series, this book provides a concise review of what students need to know in their rotations or the Boards. Each chapter is brief and includes pedagogical features such as bold key words, tables, figures, and key points boxes. This edition has been reorganized to follow the Clerkship Directors in Internal Medicine guidelines, and includes a new section on neurology, case studies, and additional tables and figures. A question-and-answer section at the end of the book includes 100 board-format questions with complete rationales for each answer choice.

Contents:
pt. I, Cardiovascular :
Chest pain
Shock
Coronary heart disease and chronic angina
Acute coronary syndromes
Heart failure
Bradyarrhythmias
Tachyarrhythmias
Hypertension
Valvular heart disease
Vascular disease
Syncope. pt. II, Respiratory :
Dyspnea
Cough
Chronic obstructive pulmonary disease
Asthma
Pulmonary embolism
Interstitial lung disease
Pleural effusions
Lung cancer. pt. III, Renal :
Acid-base disturbances
Fluid and electrolytes
Acute Kidney injury
Chronic kidney disease
Glomerular disease
Nephrolithiasis
Hematuria. pt. IV, Infectious disease :
Fever and rash
Pneumonia
Sexually transmitted infections
Urinary tract infections
Tuberculosis
Gastroenteritis
Infective endocarditis
Meningitis
HIV part I: primary care of the HIV-infected patient
HIV part II: prophylaxis and treatment of opportunistic infections in HIV. pt. V, Gastrointestinal :
Abdominal pain
Diarrhea
Dyspepsia
Inflammatory bowel disease
Hepatitis
Cirrhosis
Cholestatic liver disease
Pancreatitis
Colorectal cancer. pt. VI, Endocrine :
Weight loss
Hyperthyroidism
Hypothyroidism
Diabetes mellitus
Hypercalcemia
Adrenal insufficiency
Cushing Syndrome
Pituitary disease
Nutritional disorders
Dyslipidemia. pt. VII, Rheumatology :
Acute monoarticular arthritis
Low back pain
Rheumatoid arthritis
Seronegative spondyloarthropathies
Connective tissue diseases
Vasculitis
Amyloidosis. pt. VIII, Hematology/Oncology :
Anemia
Hemolytic anemia
Adenopathy
Bleeding disorders
Breast cancer
Prostate cancer
Leukemia
Lymphoma. pt. IX, Neurology
Headache
Delirium
Dizziness
Dementia
Stroke
Seizures.

Contents:
The neurologic examination
Neurologic investigations
The approach to coma and altered consciousness
Neuro-ophthalmology
The approach to weakness
The sensory system
Dizziness, vertigo, and syncope
Ataxia and gait disorders
Urinary and sexual dysfunction
Headache and facial pain
Aphasia and other disorders of higher cortical function
Dementia
Sleep disorders
Vascular disease
Seizures
Movement disorders
Head trauma
Systemic and metabolic disorders
Central nervous system tumors
Demyelinating diseases of the central nervous system
Infections of the nervous system
Disorders of the spinal cord
The peripheral nervous system
Disorders of the neuromuscular junction and skeletal muscle
Pediatric neurology.

Contents:
The neurologic examination
Neurologic investigations
The approach to coma and altered consciousness
Neuro-ophthalmology
The approach to weakness
The sensory system
Dizziness, vertigo, and syncope
Ataxia and gait disorders
Urinary and sexual dysfunction
Headache and facial pain
Aphasia and other disorders of higher cortical function
Dementia
Sleep disorders
Vascular disease
Seizures
Movement disorders
Head trauma
Systemic and metabolic disorders
Central nervous system tumors
Demyelinating diseases of the central nervous system
Infections of the nervous system
Disorders of the spinal cord
Radiculopathy, plexopathy, and peripheral neuropathy
Disorders of the neuromuscular junction and skeletal muscle
Pediatric neurology.

Contents:
Machine generated contents note: pt. I OBSTETRICS
1. Pregnancy and Prenatal Care
2. Early Pregnancy Complications
3. Prenatal Screening, Diagnosis, and Treatment
4. Normal Labor and Delivery
5. Antepartum Hemorrhage
6.Complications of Labor and Delivery
7. Fetal Complications of Pregnancy
8. Hypertension and Pregnancy
9. Diabetes During Pregnancy
10. Infectious Diseases in Pregnancy
11. Other Medical Complications of Pregnancy
12. Postpartum Care and Complications
pt. II GYNECOLOGY
13. Benign Disorders of the Lower Genital Tract
14. Benign Disorders of the Upper Genital Tract
15. Endometriosis and Adenomyosis
16. Infections of the Lower Female Reproductive Tract
17. Infections of the Upper Female Reproductive Tract and Systemic Infections
18. Pelvic Organ Prolapse
19. Urinary Incontinence
20. Puberty, the Menstrual Cycle, and Menopause
21. Amenorrhea
22. Abnormalities of the Menstrual Cycle
23. Hirsutism and Virilism
24. Contraception and Sterilization
25. Termination of Pregnancy
26. Infertility and Assisted Reproductive Technologies
27. Vulvar and Vaginal Neoplasia
28. Cervical Neoplasia and Cervical Cancer
29. Endometrial Cancer
30. Ovarian and Fallopian Tube Tumors
31. Gestational Trophoblastic Disease
32. Benign Breast Disease and Breast Cancer.

Summary: "Among all the WK clerkship series, Blueprints remains the best-known among medical students. While no individual Blueprints title has sold as consistently as Step-Up to Medicine, the series has maintained a consistent following over the years. In the 2016 clerkship market research study conducted through our market research team, the only series that was mentioned as frequently by both students and clerkship directors was McGraw-Hill's Case Files series"--Provided by publisher

Contents:
General pediatrics
Neonatal medicine
Adolescent medicine
Nutrition
Fluid, electrolyte, and pH management
Pulmonology
Infectious disease
Immunology, allergy, and rheumatology
Neurology
Dermatology
Cardiology
Hematology
Oncology
Gastroenterology
Endocrinology
Orthopedics
Nephrology
Urology
Genetic disorders
Emergency medicine: the acutely ill and injured child.

Contents:
Psychotic disorders
Bipolar disorders
Depressive disorders
Anxiety disorders
Trauma- and stressor- related disorders
Obessive-compulsive and related disorders
Eating disorders
Neurodevelopmental disorders and child and adolescent psychiatry
Neurocognitive disorders
Substance-related disorders
Personality disorders
Miscellaneous disorders
Special clinical topics
Legal issues
Antipsychotics
Antidepressants and somatic therapies
Mood stabilizers
Anxiolytics
Miscellaneous medications
Major adverse drug reactions
Psychological theory and psychotherapy.

Contents:
Section 1 Basic science/general pediatric otolaryngology
Section 2 Ear and related structures
Section 3 The Nose, paranasal sinuses, face, and orbit
Section 4 The Mouth, pharynx, and esophagus
Section 5 The Airway
Section 6 The Head and neck
Section 7 Communication disorders.

Summary: This book covers the epidemiology, mechanism, risk, various types of injuries, and practical approaches to treating children who have sustained blunt abdominal trauma. It includes dedicated chapters on each key aspect of pediatric blunt abdominal injuries, and explains in detail primary resuscitation and ancillary care for pediatric abdominal trauma. A separate chapter on imaging and interventional imaging helps pediatric caregivers select the right modality in the management of these patients. In addition, the book covers the management of hollow viscus injury and solid organ injury following blunt abdominal trauma. The content is supplemented with detailed flowcharts wherever required to help familiarize readers with the indications and to assist them in surgical decision-making. The book offers a valuable guide for practicing pediatric surgeons, residents in pediatric surgery and trauma surgeons, as well as for general surgeons, general surgery residents, practicing pediatricians and general physicians.

Contents:
Basic concepts and indications for transplantation
Types of transplants and sources of stem cells
Pretransplant issues
Transplant preparative regimens, cellular infusion, acute complications, and engraftment
Graft-versus-host disease
Post-transplant issues
Survivorship issues
Professional practice.

Summary: Board Review in Preventive Medicine and Public Health prepares physicians for their initial and recertification board exams in the related specialties of preventive, occupational and aerospace medicine. Formatted in a question and answer based style that imitates material on specialty exams, each question is linked to a detailed answer. The book contains over 640 question and answer sets covering areas such as general public health, health management, health law, community health, infectious disease, clinical preventive medicine, occupational medicine, aerospace medicine, environmental medicine, correctional (prison) medicine, emergency preparedness, epidemiology and biostatistics. The book is an essential board preparation for physicians with a background in the fields of preventive medicine, occupational medicine, and aerospace medicine. It is also useful for medical students, public health students and those wishing to gain an understanding of the key points in these fields.

Contents:
Internal medicine
Surgery
Obstetrics and gynecology
Pediatrics
Family medicine
Psychiatry
Neurology
Dermatology
Ophthalmology
Radiology
Emergency medicine
Ethics/law/clinical studies.

Summary: Boards & Beyond from McGraw Hill Medical supports medical students with on-demand video libraries and question banks designed to build a solid foundation of understanding that goes beyond memorization. Students in the US and around the globe use Boards & Beyond subscriptions to supplement their classes and prepare for board exams, core clerkships, and successful careers.

Contents:
Body composition in perspective / Henry Lukaski
Assessment of human body composition : methods and limitations / Hannes Gatterer, Kai Schenk, and Martin Burtscher
Assessment of muscle mass / Donald Dengel, Christiana J Raymond, and Tyler Bosch
Hydration status and performance / Ronald Maughan and Susan Shirreffs
Physical activity on growth and development of youth / Robert Malina and Manuel J. Coelho e Silva
Anthropometry in physical performance and health / Arthur Stewart and Tim Ackland
Physical activity and adipose tissue redistribution in obese adults / Brittany P. Hammond, Andrea M. Brennan, and Robert Ross
Physical activity and body composition changes in overweight and obese children / Scott Going, Jennifer Bea, and Joshua Farr
Body composition changes with training : methodological implications / Luis Sardinha and Diana Santos
Endurance athletes / Jordan Moon and Kristina Kendall
Speed, power and strength athletes / David David Fukuda, Jeffery Stout, and Jay Hoffman
Weight-sensitive sports / Analiza Silva, Diana Santos, and Catarina Matias
Military / Karl Friedl
Body composition and public safety : the industrial athlete / Paul Davis and Mark Abel
Dietary protein and physical training effects on body composition and physical performance / Michaela C Devries, Sara Y Oikawa, and Stuart Phillips
Supplements, body composition and performance / Karl Friedl
Diet and exercise approaches for reversal of exercise-associated amenorrhea / Lynn Cialdella Kam and Melinda Manore.

Contents:
The physics of computed tomography
CT radiation dose and management
Contrast administration
Mediastinum
Lung
Airways
Pleura, diaphragm, and chest wall
Heart and thoracic aorta
Liver and biliary
Pancreas
Kidneys, ureters, and bladder
Adrenal glands
Spleen
Gastrointestinal tract
Peritoneum and peritoneal spaces
Retroperitoneum, vessels, and nodes
Pelvis
Trauma.

Summary: This book equips readers with the knowledge required to improve diagnosis and treatment and to implement integrated prevention programs in patients with eating and weight disorders. It does so by providing a comprehensive, up-to-date review of research findings and theoretical assumptions concerning the interface and interactions between body image and such disorders as anorexia nervosa, bulimia nervosa, binge eating disorder, other specified feeding and eating disorders, orthorexia nervosa, overweight, and obesity. After consideration of issues of definition and classification, the opening part of the book examines the concept of body image from a variety of viewpoints. A series of chapters are then devoted to the assessment of the multidimensional construct “body image”, to dysmorphophobia/body dysmorphic disorder, and to muscle dysmorphia. The third part discusses body image in people suffering from different eating disorders and/or overweight or obesity, and two final chapters focus on body image in the integrated prevention of eating disorders and obesity, and cultural differences regarding body image. The book will be of interest to all health professionals who work in the fields of psychiatry, clinical psychology, eating disorders, obesity, body image, adolescence, public health, and prevention.

Contents:
Imaging of various body regions
Head and neck
Mediastinum
Heart and pericardium
Major vessels
Lung and pleura
Breast
Liver
Gallbladder and biliary tract
Pancreas
Gastrointestinal tract
Spleen and lymphatic system
Adrenal glands
Kidney and urinary tract
Female pelvis
Male pelvis.

Summary: The Body Is Not an Apology The Power of Radical Self-Love Against a global backdrop of war, social upheaval, and personal despair, there is a growing sense of urgency to challenge the systems of oppression that dehumanize bodies and strip us of our shared humanity. Rather than feel helpless in the face of oppression, world-renowned activist, performance poet, and author Sonya Renee Taylor teaches us how to turn to the power of radical self-love in her new book, The Body Is Not an Apology. Radical self-love is the guiding framework that transforms the learned self-hatred of our bodies and the prejudices we have about other people's bodies into a vision of compassion, equity, and justice. In a revolutionary departure from the corporate self-help and body-positivity movement, Taylor forges the inextricable bond between radical self-love and social justice. The first step is recognizing that we have all been indoctrinated into a system of body shame that profits off of our self-hatred. When we ask ourselves, "Who benefits from our collective shame?" we can begin to make the distinction between the messages we are receiving about our bodies or other bodies and the truth. This book moves us beyond our all-too-often hidden lives, where we are easily encouraged to forget that we are whole humans having whole human experiences in our bodies alongside others. Radical self-love encourages us to embark on a personal journey of transformation with thoughtful reflection on the origins of our minds and bodies as a source of strength. In doing this, we not only learn to reject negative messages about ourselves but begin to thwart the very power structures that uphold them. Systems of oppression thrive off of our inability to make peace with bodies and difference. Radical self-love not only dismantles shame and self-loathing in us but has the power to dismantle global systems of injustice-because when we make peace with our bodies, only then do we have the capacity to truly make peace with the bodies of others.

Summary: An expert on traumatic stress outlines an approach to healing, explaining how traumatic stress affects brain processes and how to use innovative treatments to reactivate the mind's abilities to trust, engage others, and experience pleasure. --Publisher's description.

Contents:
Prologue : Facing trauma
Part I. The rediscovery of trauma : Lessons from Vietnam veterans
Revolutions in understanding mind and brain
Looking into the brain: the neuroscience revolution
Part II. This is your brain on trauma : Running for your life: the anatomy of survival
Body-brain connections
Losing your body, losing your self
Part III. The minds of children : Getting on the same wavelength: attachment and attunement
Trapped in relationships: the cost of abuse and neglect
What's love got to do with it?
Developmental trauma: the hidden epidemic
Part IV. The imprint of trauma : Uncovering secrets: the problem of traumatic memory
The unbearable heaviness of remembering
Part V. Paths to recovery : Healing from trauma: owning your self
Language: miracle and tyranny
Letting go of the past: EMDR
Learning to inhabit your body: yoga
Putting the pieces together: self-leadership
Filling in the holes: creating structures
Applied neuroscience : rewiring the brain fear-driven mind with brain/computer interface technology
Finding your voice: communal rhythms and theater
Epilogue : Choices to be made
Appendix : Consensus proposed criteria for developmental trauma disorder.

Summary: The dynamics of body metabolism are changed in the disease process and interact with physical activity. The alteration of metabolism and its consequences raise the need for simple and reliable methods for assessment of body composition. The chapters aim to investigate various interacting components converging on metabolic changes in lung and muscle tissues taking into consideration the drug effects. The effects of exercise and nutritional status are dealt with at a great extent.

Contents:
Body composition in heavy smokers / O. Rom-- Metabolic and immunological consequences of vitamin D deficiency in obese children / B. Pyrz̀ak
Markers of bone metabolism in children with Nephrotic Syndrome treated with corticosteroids / Małgorzata. Pańczyk-Tomaszewska
Endurance training and the risk of bronchial asthma in female cross-country skiers / A. Żebrowska
Effects of inspiratory muscle training on resistance to fatigue of respiratory muscles during exhaustive exercise / M.O. Segizbaeva
Nutritional status in chronic obstructive pulmonary disease and systemic sclerosis / D. Mękal
Gradual versus continuous Increase of load in ergometric tests / A.M. Preisser
Evaluation of volumetric changes in differential diagnosis of brain atrophy and active hydrocephalus / E. Szczepek.

Contents:
Body reshaping for health and beauty
A first look at the meridian system in TCM
Who can benefit from this treatment?
Body posture and homeostasis
Six body types
Anatomical approach type M1, M2, M3
Muscle meridian therapy and skin cutaneous therapy
Treatment methods
Specific clinical cautions and application.

Summary: Improve your technique, treat patients with confidence, and obtain optimal results using today's most advanced body shaping treatments with guidance from Body Shaping: Skin, Fat and Cellulite, a volume in the Procedures in Cosmetic Dermatology Series. Renowned cosmetic dermatologists-Drs. Orringer, Alam, and Dover-provide you with procedural how-to's and step-by-step advice on proper techniques, pitfalls, and tricks of the trade, equipping you to successfully incorporate the very latest for skin tightening, fat reduction, and sculpting procedures into your busy practice!

Contents:
Skin laxity : anatomy, etiology, and treatment indications
Lasers and lights : skin tightening
Radiofrequency treatment : skin tightening
Micro-focused ultrasound : skin tightening
Subcutaneous fat : anatomy, physiology, and treatment indications
Cryolipolysis : fat reduction
Radiofrequency treatment : fat reduction
Ultrasound treatment : fat reduction
Liposuction, ultrasound-assisted and powered : fat reduction
Laser lipolysis : fat reduction
Injectable fat-reducing therapies : fat reduction
Cellulite : anatomy, etiology, treatment indications
Massage/mechanical techniques : cellulite reduction
Lasers and lights : cellulite reduction
Radiofrequency and ultrasound : cellulite reduction
Subcision : cellulite reduction.

Contents:
Microbiology of bone and joint infections
Pharmacokinetics and pharmacodynamics of antibiotics in bone
Preclinical models of infection in bone and joint surgery
Native joint arthritis in children
Native joint arthritis
Septic arthritis of axial joints
Periprosthetic joint infection : general aspects
Periprosthetic joint infection after total hip and knee arthroplasty
Periprosthetic joint infection after shoulder arthroplasty
Periprosthetic joint infection after elbow arthroplasty
Periprosthetic joint infection after ankle arthroplasty
Osteomyelitis : classification
Osteomyelitis in children
Acute osteomyelitis in adults
Subacute osteomyelitis : tuberculous and brucellar vertebral osteomyelitis
Chronic osteomyelitis in adults
Diabetic foot osteomyelitis
Osteomyelitis of the jaws
Implant-associated osteomyelitis of long bones
Implant-associated vertebral osteomyelitis
Postoperative sternum osteomyelitis.

Summary: "The prevalence of most bone and joint infections is steadily increasing, mainly due to the rising life expectancy of the population, and the increasing use of bone fixation devices and prosthetic joints. For frequent infectious diseases, such as respiratory tract, urinary tract and bloodstream infections, many diagnostic and therapeutic aspects have been studied in a controlled fashion [e.g. 1-3]. In contrast, in the field of bone and joint infections, randomized controlled trials are rare. Exceptions are a randomized controlled study on the role of rifampin in patients with orthopedic implant-associated infections, and a controlled trial comparing two different durations of antibiotic treatment in patients with vertebral osteomyelitis [4, 5]. Therefore, diagnostic and therapeutic advice has to be based mainly on individual clinical expert knowledge and observational studies [6-10]. The optimal diagnostic and therapeutic management of bone and joint infections needs a special know-how in different fields of medicine. Many physicians have only limited clinical experience, since arthritis and osteomyelitis are rare infectious diseases. Therefore, a multidisciplinary approach to these infections is desirable. Only for a few topics, internationally accepted guidelines for the management of bone and joint infections are available [11-13]. In addition, publications on the clinical practice comprising different aspects of these infections are scarce. The aim of this book is to close this gap with texts from a multidisciplinary team of experts in the field. Indeed, specialists in Microbiology, Clinical Pharmacology, Preclinical Research, Pediatrics, Pediatric and Adult Orthopedic Surgery, Infectious Diseases, and Cardiovascular Surgery contributed to this book. This broad spectrum of expertise made it possible to cover a wide range of pathophysiological, epidemiological, diagnostic and therapeutic aspects of bone and joint infection. The principal focus of the book is on clinical practice. It should enable clinicians managing patients according to the best available evidence"-- Provided by publisher

Contents:
Diagnostic Approach in Bone and Joint Infections
Unusual Microorganisms in Periprosthetic Joint Infection
Identification of Pathogens in Bone and Joint Infections by Non-Culture Techniques
Bacteriophages for treatment of biofilm infections
Pharmacokinetics and Pharmacodynamics of Antibiotics in Bone
Preclinical Models of Infection in Bone and Joint Surgery
Native Joint Arthritis in Children
Native Joint Arthritis in Adults
Septic Arthritis of Axial Joints
Periprosthetic Joint Infection : General Aspects
Periprosthetic Joint Infection after Total Hip and Knee Arthroplasty
Periprosthetic Joint Infection after Shoulder Arthroplasty
Periprosthetic Joint Infection after Elbow Arthroplasty
Periprosthetic Joint Infection after Ankle Arthroplasty
Osteomyelitis : Classification
Osteomyelitis in Children
Acute Osteomyelitis in Adults
Subacute Osteomyelitis : Tuberculous and Brucellar Vertebral Osteomyelitis
Chronic Osteomyelitis in Adults
Diabetic Foot Osteomyelitis
Osteomyelitis of the Jaws
Fracture-related Infection of Long Bones
Implant-Associated Vertebral Osteomyelitis
Postoperative Sternal Osteomyelitis.

Summary: All European countries, including those that have recently joined the European Union or are candidates for membership, currently show a clear trend towards an increasing number of accidental injuries. This holds true for a range of injuries, including accidents among the elderly, sports injuries, and trauma due to traffic accidents. The increase in the number of injuries is accompanied by rising expectations among patients, who anticipate good functional results even after serious injuries. Despite these developments, trauma surgery is not yet established as an independent field in all European countries. Against this background, there is a clear need for a book that covers the state of the art in trauma surgery. This volume, which focuses on bone and joint injuries orthopedic trauma is intended to help to meet this need. It will also serve to harmonize the practice of trauma surgery within the European Union and to prepare for the UEMS EBSQ trauma surgery.

Contents:
1. Rotator Cuff Tears / Martin Jaeger, Kaywan Izadpanah, and Norbert P. Südkamp
2. Posttraumatic Shoulder Instability / Martin Jaeger, Kaywan Izadpanah, and Norbert P. Südkamp
3. Proximal Humeral Fractures / Martin Jaeger, Kaywan Izadpanah, and Norbert P. Südkamp
4. Treatment of Acromioclavicular Joint Dislocation / Klemens Horst, Thomas Dienstknecht, and Hans- Christoph Pape
5. Clavicle Fractures / Hans-Jörg Oestern
6. Scapula Fractures / Jan Friederichs and Volker Bühren
7. Humeral Shaft Fractures / Pol M. Rommens
8. Distal Humerus Fractures / Klaus J. Burkhart, Pol M. Rommens, and Lars Peter Müller
9. Coronoid Fractures / Klaus J. Burkhart, Pol M. Rommens, and Lars Peter Müller
10. Olecranon Fractures / Tobias E. Nowak and Pol M. Rommens
11. Radial Head Fractures / Klaus J. Burkhart, Pol M. Rommens, and Lars Peter Müller
12. Forearm Shaft Fractures / Hans-Jörg Oestern
13. Distal Radius Fractures / Hans-Jörg Oestern
14. Management of Hand Injuries / Susanne Hellmich and P.M. Vogt
15. Cervical Spine Injuries / Christoph Josten and Jan-Sven Jarvers
16. Spine / Markus Schultheiss, Daniel Gulkin, and Florian Gebhard
17. Pelvic and Acetabular Fractures / Reiner Wirbel and Tim Pohlemann
18. Pipkin Fractures / Vilmos Vécsei
19. Femoral Neck Fractures / Vilmos Vécsei
20. Pertrochanteric Fractures / Vilmos Vécsei
21. Femoral Shaft Fractures / Vilmos Vécsei
22. Distal Femur Fractures / Arne Berner and Michael Schütz
23. Patella Fractures / Hans-Jörg Oestern
24. Knee Ligament Injuries / Phillip Forkel and Wolf Petersen
25. Tibial Plateau Fractures / Philipp Kobbe and Hans-Christoph Pape
26. Tibial Shaft Fractures / Philipp Lichte and Hans-Christoph Pape
27. Fractures of the Tibial Pilon / Richard Martin Sellei and Hans-Christoph Pape
28. Foot and Ankle Injuries / Susanne Rein, Ken Jin Tan, Stefan Rammelt, and Hans Zwipp
29. Pediatric Fractures and Dislocations / Christoph Nau, Dorien Schneidmüller, and Ingo Marzi.

Contents:
1. Approach to bone and soft tissue tumors / Matthew T. Houdek
2. Adjuvant techniques: immunohistochemistry, cytogenetics, and molecular genetics / Gregory W. Charville
3. Fibroblastic and myofibroblastic tumors / Elizabeth G. Demicco
4. Fibrohistiocytic tumors / Elizabeth G. Demicco
5. Adipocytic tumors / David Creytens
6. Smooth muscle tumors / Alexander K. Nobori and Sarah M. Dry
7. Skeletal muscle tumors / Raf Sciot
8. Tumors of perivascular cells / Leona Doyle
9. Gastrointestinal stromal tumor / Adrian Marino-Enriquez
10. Vascular tumors of soft tissue and bone / Yin Pun Hung, G. Petur Nielsen and Andrew L. Folpe
11. Nerve sheath tumors / Karen J. Fritchie
12. Matrix-forming tumors of soft tissue / Jen-Chieh Lee and Hsuan-Ying Huang
13. Tumors of synovial and tenosynovial tissue / Elizabeth G. Demicco and G. Petur Nielsen
14. Undifferentiated small round cell sarcomas of bone and soft tissue / Brendan C. Dickson
15. Mesenchymal tumors of miscellaneous type or uncertain lineage / Andrew L. Folpe
16. Bone-forming tumors / Daniel P. Cassidy and Andrew E. Rosenberg
17. Cartilage-forming tumors / Darcy A. Kerr and G. Petur Nielsen
18. Fibroblastic and fibrohistiocytic tumors / Daniel Baumhoer
19. Hematolymphoid neoplasms of bone / Judith A. Ferry
20. Giant cell tumor of bone / Akihiko Yoshida
21. Notochordal cell tumors / Angela R. Shih and G. Petur Nielsen
22. Osteofibrous dysplasia/adamantinoma / Alyaa Al-Ibraheemi
23. Cystic tumors of bone / Scott E. Kilpatrick and John D. Reith
24. Fibrous dysplasia of bone / Scott E. Kilpatrick and John D. Reith
25. Metastases / John D. Reith and Scott E. Kilpatrick.

Summary: This book is a complete guide to the essentials of orthopedics. Covers the full range of conditions, injuries, and diseases encountered in operating and emergency room settings, including fractures, dislocations, bone/joint infections, and spinal cord injuries.

Contents:
Intro
Foreword
Contents
Chapter 1: Anatomy Essentials
Upper Extremity
Shoulder
Bones
Muscles
Neurovascular Structures
Surgical Approach
Arm
Bones
Muscles
Neurovascular Structures
Surgical Approach
Elbow
Bones
Muscles
Neurovascular Structures
Surgical Approach
Forearm
Bones
Muscles
Neurovascular Structures
Surgical Approach
Wrist
Bones
Muscles
Neurovascular Structures
Surgical Approach
Hand
Bones
Muscles
Neurovascular Structures
Surgical Approach
Lower Extremity
Pelvis
Bones Muscles
Neurovascular Structures
Surgical Approach
Hip
Bones
Muscles
Neurovascular Structures
Surgical Approach
Femur
Bones
Muscles
Neurovascular Structures
Surgical Approach
Knee
Bones
Muscles
Neurovascular Structures
Surgical Approach
Lower Leg
Bones
Muscles
Neurovascular Structures
Surgical Approach
Ankle
Bones
Muscles
Neurovascular Structures
Surgical Approach
Foot
Bones
Muscles
Neurovascular Structures
Surgical Approach
Spine
Cervical Spine
Bones
Neurovascular Structures Surgical Approach (Fig. 1.56)
Thoracic Spine
Bones
Neurovascular Structures
Surgical Approach
Lumbar Spine
Bones
Neurovascular Structures
Surgical Approach
Sacrum
Bones
Neurovascular Structures
Chapter 2: Physical Exam Fundamentals
Definition
Principles
Upper Extremity
Shoulder
Elbow
Hand and Wrist
Lower Extremity
Hip and Pelvis
Knee
Foot and Ankle
Spine
Chapter 3: Managing the Floor
Postoperative Check/Rounding
Lab Abnormalities
Anemia
Hypoglycemia
Hyponatremia
Hyperkalemia
Hypokalemia
Hypotension Hypoxia
Tachycardia
Fever
Low Urine Output (Oliguria)
Delirium
Seizure
Chest Pain
Pain Management
Wound Issues
Erythema
Drainage
Dehiscence
Chapter 4: Orthopedic Emergencies
Definition
Septic Joint
Definition
Why Is this Emergent?
Causes
Diagnosis
Treatment
Suppurative Flexor Tenosynovitis
Definition
Why Is this Emergent?
Causes
Diagnosis
Treatment
Necrotizing Fasciitis
Definition
Why Is this Emergent?
Causes
Diagnosis
Treatment
Compartment Syndrome
Definition
Why Is this Emergent?
Causes Diagnosis
Treatment
Open Fracture
Definition
Why Is this Emergent?
Causes
Diagnosis
Treatment
Cauda Equina Syndrome
Definition
Why Is this Emergent?
Causes
Diagnosis
Treatment
Chapter 5: Emergency Room Consultations
Emergency Room Consults
High-Energy Trauma Patient and Fracture Management
Pediatric Fractures
Dislocations
Spinal Cord Injury (SCI)
Tendon Rupture/Laceration
Fingertip Amputation
Postoperative Complications
Other Common ER Consults:
Chapter 6: Sports Injuries
Definition
Team Physician Responsibilities