BookRaymond H.W. Lam, Weiqiang Chen.
Summary: This textbook provides essential knowledge for biomedical product development, including material properties, fabrication processes and design techniques for different applications, as well as process design and optimization. This book is multidisciplinary and readers can learn techniques to apply acquired knowledge for various applications of biomedical design. Further, this book encourages readers to discover and convert newly reported technologies into products and services for the future development of biomedical applications. This is an ideal book for upper-level undergraduate and graduate students, engineers, technologists, and researchers working in the area of biomedical engineering and manufacturing. This book also: Provides a comprehensive set of fundamental knowledge for engineering students and entry level engineers to design biomedical devices. Offers a unique approach to manufacturing of biomedical devices by integrating and formulating different considerations in process design tasks into optimization problems. Provides a broad range of application examples to guide readers through the thinking process of designing and manufacturing biomedical devices, from basic understanding about the requirements and regulations to a set of manufacturing parameters.
Contents:
Intro; Preface; Acknowledgments; Contents; About the Authors;
Chapter 1: Introduction to Biomedical Devices; 1.1 Overview of Biomedical Devices; 1.2 Biomedical Device Industry; 1.3 Regulatory Issues; 1.4 The Demands for Biomedical Engineers; 1.5 Human System Basics; 1.6 Surgical Tools; 1.6.1 Surgical Scalpel; 1.6.2 Surgical Sutures; 1.7 Devices for Sensory Organs; 1.7.1 Skin Devices; 1.7.2 Contact Lenses; 1.8 Cardiovascular Devices; 1.8.1 Artificial Heart Valve; 1.8.2 Pacemaker; 1.8.3 Vascular Stent; 1.9 Skeleton Devices; 1.10 Tissue Grafts; 1.11 Summary; References and Further Reading Part I: Biomaterials
Chapter 2: Basic Material Properties; 2.1 Introduction; 2.2 Solid Properties; 2.2.1 Direct Stress and Strain; 2.2.2 Stress-Strain Diagram; 2.2.3 Shear Stress and Strain; 2.2.4 Poissonś Ratio; 2.3 Thermal Properties; 2.3.1 Thermal Strain and Deformation; 2.3.2 Specific Heat Capacity; 2.3.3 Changes of Moduli of Elasticity and Rigidity with Temperature; 2.4 Fluidic Properties; 2.4.1 Viscosity; 2.4.2 Types of Flows; 2.5 Surface and Interfacial Properties; 2.5.1 Surface Roughness; 2.5.2 Friction and Lubrication at the Tool-Workpiece Interface; 2.5.3 Adhesion/Binding Strength Problem 3.4Problem 3.5; Problem 3.6; Problem 3.7; Problem 3.8; Problem 3.9; Problem 3.10; References and Further Reading;
Chapter 4: Polymers; 4.1 Overview; 4.2 Basic Characteristics; 4.3 Polymeric Synthesis; 4.3.1 Overview; 4.3.2 Addition; 4.3.3 Condensation; 4.3.4 Number- and Weight-Average Molecular Weights; 4.4 Physical Properties; 4.4.1 Relaxation, Transition, and Melt Viscosity; 4.4.2 Theory of Melting Point Depression; 4.4.3 Glass Transition as an Iso-Free-Volume State; 4.4.4 Rubbery Elasticity; 4.4.5 Relationships of Tm and Tg with Molecular Weight; 4.5 Common Polymeric Biomaterials ProblemsProblem 2.1; Problem 2.2; Problem 2.3; Problem 2.4; Problem 2.5; Problem 2.6; Problem 2.7; Problem 2.8; Problem 2.9; References and Further Reading;
Chapter 3: Metals and Alloys; 3.1 Overview; 3.2 Crystalline Characteristic of Metals; 3.2.1 Crystal Direction and Planes; 3.2.2 Line Defects and Grains; 3.3 Common Physical Properties; 3.3.1 Interatomic Attraction and Repulsion; 3.3.2 Corrosion; 3.3.3 Biocompatibility; 3.4 Metal Strengthening; 3.4.1 Work Hardening; 3.4.2 Grain Size Control; 3.4.3 Alloying; 3.5 Common Metallic Biomaterials; Problems; Problem 3.1; Problem 3.2; Problem 3.3 ProblemsProblem 4.1; Problem 4.2; Problem 4.3; Problem 4.4; Problem 4.5; Problem 4.6; Problem 4.7; Problem 4.8; Problem 4.9; Problem 4.10; References and Further Reading;
Chapter 5: Ceramics; 5.1 Overview; 5.2 General Characteristics; 5.2.1 Basic Physical Properties; 5.2.2 Porosity; 5.2.3 Fracture and Bridging Contribution; 5.2.4 Slip Dislocation; 5.2.5 Biocompatibility; 5.3 Common Bioceramics; 5.3.1 Basic Bioceramics; 5.3.2 Resorbable Ceramics; Problems; Problem 5.1; Problem 5.2; Problem 5.3; Problem 5.4; Problem 5.5; Problem 5.6; Problem 5.7; Problem 5.8; References and Further Reading