Books

E

  • 2008 NAP
    [prepared by] Sally Robinson, Robert Pool, and Robert Giffin ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies.
    1. Introduction -- 2. Investigative Toxicology: The State of the Art -- 3. Screening Technologies I: Human Cell-Based Approaches -- 4. Screening Technologies II: Toxicogenomics -- 5. Screening Technologies III: Metabolomics -- 6. Screening Technologies IV: Pharmacogenetics -- 7. Qualifying Biomarkers -- 8. Pharmacovigilance -- 9. Integration -- 10. The Future of Safety Science.
  • 2009 Karger
    editors, Satish C. Kalhan, Andrew M. Prentice, Chittaranjan S. Yajnik.
    Global changes in diet and activity patterns as drivers of the nutrition transition / Popkin, B.M. -- Regional case studies : India / Reddy, K.S. -- Regional case studies : China / Yin, S. -- Regional case studies : Africa / Prentice, A.M. -- Obesity in emerging nations : evolutionary origins and the impact of a rapid nutrition transition / Prentice, A.M. -- Prenatal origins of undernutrition / Christian, P. -- Postnatal origins of undernutrition / Prost, M.-A. -- Malnutrition, long-term health, and the effect of nutritional recovery / Sawaya, A.L. ... [et al.] -- The role of epigenetics in mediating environmental effects on phenotype / Morgan, D.; Whitelaw, E. -- Metabolism of methionine in vivo : impact of pregnancy, protein restriction, and fatty liver disease / Kalhan, S.C. -- Adiposity and comorbidities : favorable impact of caloric restriction / Ravussin, E.; Redman, L.M. -- Obesity, inflammation, and macrophages / Subramanian, V.; Ferrante, A.W., Jr. -- Obesity, hepatic metabolism and disease / Edmison, J.M.; Kalhan, S.C.; McCullough, A.J. -- Imperative of preventive measures addressing the life-cycle / Yajnik, C.S. -- New approaches to optimizing early diets / Polberger, S. -- Prevention of low birthweight / Alam, D.S. -- Community-based approaches to address childhood undernutrition and obesity in developing countries / Shetty, P.
  • 2007 Springer
    Richard M. Satava, Achille Gaspari, Nicola Di Lorenzo, [editors].
  • 2013 Future Med
    editors, Masao Omata, Tatsuo Kanda.
    Hepatitis C virus infection : from discovery to eradication / Masao Omata & Tatsuo Kanda -- Interferons in clinical trials / Tatsuo Kanda, Osamu Yokosuka & Masao Omata -- Protease inhibitors / Marion Corouge, Philippe Sogni & Stanislas Pol -- NS5A inhibitor : daclatasvir / Kazuaki Chayama & C. Nelson Hayes -- Toll-like receptor agonists for nonresponders to HCV treatment : hope versus promise? / Valérie Martel-Laferrière & Douglas Dieterich -- Treatment options in HIV-HCV-coinfected patients / Philippe Sogni, Marion Corouge & Stanislas Pol -- Treatment options for dual HCV/HBV coinfection / Chun-Jen Liu & Jia-Horng Kao -- HCV treatment in patients with metabolic syndrome / Luigi E. Adinolfi, Rosa Zampino, Luciano Restivo, Amedeo Lonardo & Paola Loria -- Future directions in hepatitis C therapy / Stevan A. Gonzalez -- Index.
  • 2011 Springer
    edited by Stan Kaye, Robert Brown, Hani Gabra, Martin Gore.
    Systemic Therapy for Ovarian Cancer, Current Treatment, Recent Advances, and Unmet Needs / Susana Banerjee, Michael A. Bookman, and Martin Gore -- Discovery of Novel Targets / John Farley and Michael J. Birrer -- Novel Anti-angiogenic Therapies in Ovarian Cancer / Jurjees Hasan and Gordon Jayson -- Targeting the AKT Pathway in Ovarian Cancer / Euan A. Stronach ... [et al.] -- Inhibition of the Src Oncogene : Therapeutic Potential in Ovarian Carcinoma / Liz Y. Han and Anil K. Sood -- Tumour-Specific Synthetic Lethality : Targeting BRCA Dysfunction in Ovarian Cancer / Timothy A. Yap ... [et al.] -- Targeting Inflammatory Pathways in Epithelial Ovarian Cancer / Jermaine Coward and Frances Balkwill -- Epithelial-to-Mesenchymal Transition and Cellular Membrane Receptors in Ovarian Cancer : Moving Forward in the Era of Molecularly Targeted Therapy / Lainie P. Martin, Julia J. Perkins, and Russell J. Schilder -- Epigenetic Therapies / Robert Brown, Nadine Chapman-Rothe, and Ros Glasspool -- Ovarian Cancer Immunology and Immunotherapy / Sadaf Ghaem-Maghami and Martin Gore -- Ovarian Cancer Progenitor/Stem Cells: Therapeutic Potential / Susan K. Murphy and Andrew Berchuck -- Potential for α-Folate Receptor-Targeted Treatment for Ovarian Cancer / Chau H.M. Ng and Ann L. Jackman -- New Insights into Tubulin Binders / Carles Escriu and James D. Brenton.
  • 2012 Future Med
    editors, Francesco M. Marincola, Paolo Ascierto, John M. Kirkwood.
    Emerging therapeutics for melanoma / Francesco M. Marincola, Paolo Ascierto & John M. Kirkwood -- Melanoma pathophysiology and drug targets / Giuseppe Palmieri, Carla Rozzo, Giusy Gentilcore & Paolo Antonio Ascierto -- Melanoma classification, diagnosis and staging / Mohammed Kashani-Sabet -- Melanoma prevention / Pamela B. Cassidy, Douglas Grossman & Sancy A. Leachman -- Surgical treatment of melanoma : from excision to sentinel node biopsy / Nicola Mozzillo & Corrado Caracò -- Adjuvant therapy in melanoma / Diwakar Davar, Ahmad A. Tarhini & John M. Kirkwood -- Immunostimulatory monoclonal antibodies for melanoma treatment / Miguel Fernandez de Sanmamed, Jose L. Perez-Gracia, Salvador Martín-Algarra & Ignacio Melero -- New signal transduction inhibitors / Keith T. Flaherty -- Melanoma vaccines in development / Ruggero Ridolfi, Laura Ridolfi, Stefania V.L. Nicoletti & Massimo Guidoboni -- Melanoma and biomarkers of immunoresponsiveness : predicting the clinical outcome of immunotherapy / Davide Bedognetti, Ena Wang, Mario Roberto Sertoli & Francesco M. Marincola -- Uveal melanoma / Paola Queirolo, Graziano Caltabiano & Francesco Spagnolo -- Management of melanoma brain metastases in the era of targeted therapies / Daniela Gonsalves Shapiro, Michael T. Shapiro & Wolfram E. Samlowski -- Which therapy for which patient? / Antoni Ribas -- Index.
  • 2013 Springer
    Michael K. Danquah, Ram I. Mahato, editors.
  • 2007 Karger
    volume editor, Sunil K. Lal.
    The Singapore contribution in the battle against the severe acute respiratory syndrome / Fielding, B.C., Tan, Y.-J. -- Avian influenza in Thailand / Puthavathana, P. ... [et al.] -- Emerging viral diseases of fish and shrimp / Wang, M. ... [et al.] -- Avian influenza H5N1 virus: an emerging global pandemic / Lal, S.K., Chow, V.T.K. -- Henipaviruses: new threats for Southeast Asia and Australia / McCormack, J., Smith, G. -- Ross River virus: an arthritogenic alphavirus of significant importance in the Asia Pacific / Tupanceska, D. ... [et al.] -- Emerging and re-emerging infectious diseases in our global village / Heymann, D.L. -- Role of a pathology laboratory in SARS and other emerging infections / Nicholls, J., Peiris, J.S.M. -- The fight against emerging viral diseases in Asia / Lam, S.K.
  • 2007 ScienceDirect
    editor: Edward Tabor.
  • v. 1-3, 2007.
    [edited by] David L. Rimoin ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2013 ScienceDirect
    2013 ClinicalKey
    edited by David L. Rimoin, Reed E. Pyeritz and Bruce Korf.
    For decades, Emery & Rimoin's Principles and Practice of Medical Genetics has provided the ultimate source for practicing clinicians to learn how the study of genetics can be integrated into practice. With advances in high-throughput technologies propelling the closer integration of lab and clinical work, this sixth edition bridges the gap between high-level molecular genetics and individual application. This comprehensive yet practical resource emphasizes theory and research fundamentals related to applications of medical genetics across the full spectrum of inherited disorders.
  • 2012 ClinicalKey
    Peter D. Turnpenny, Sian Ellard.
    Master the genetics you need to know with the updated 14th Edition, by Drs. Peter Turnpenny and Sian Ellard. Review the field's latest and most important topics with user-friendly coverage designed to help you better understand and apply the basic principles of genetics to clinical situations. Learning is easy with the aid of clear, full-color illustrative diagrams, a wealth of clinical photographs of genetic diseases, multiple-choice and case-based review questions, end-of-chapter summaries, and convenient.
  • 2007
    Peter Turnpenny, Sian Ellard.
    Status: Not Checked OutLane Catalog Record
    The history and impact of genetics in medicine -- The cellular and molecular basis of inheritance -- Chromosomes and cell division -- DNA technology and applications -- Mapping and identifying genes for monogenic disorders -- Developmental genetics -- Patterns of inheritance -- Mathematical and population genetics -- Polygenic and multifactorial inheritance -- Hemoglobin and the hemoglobinopathies -- Biochemical genetics -- Pharmacogenetics -- Immunogentics -- Cancer genetics -- Genetic factors in common diseases -- Congenital abnormalities and dysmorphic syndromes -- Genetic counseling -- Chromosome disorders -- Single-gene disorders -- Screening for genetic disease -- Prenatal testing and reproductive genetics -- Risk calculation -- Treatment of genetic disease -- Ethical and legal issues in medical genetics.
  • 2005/2006
    Jeffrey Jay Tung.
    Status: Not Checked OutLane Catalog Record
  • 2008 Springer
    Ad J.J.M. Vingerhoets, Ivan Nyklíček, Johan Denollet, editors.
    Introduction: Emotions, emotion regulation, and health / Johan Denollet, Ivan Nyklíček, Ad J.J.M. Vingerhoets -- Coping styles and aggression : a biobehavioral approach / Jaap M. Koolhaas, Sietse F. de Boer -- New avenues in alexithymia research : the creation of alexithymia types / Peter Paul Moormann ... [et al.] -- Current issues in repressive coping and health / Lynn B. Myers ... [et al.] -- Why crying improves our well-being : an attachment-theory perspective on the functions of adult crying / Michelle C.P. Hendriks .. [et al.] -- Emotional intelligence : relationships to stress, health, and well-being / Guus L. van Heck, Brenda L. den Oudsten -- Emotion expression in depression : emerging evidence for emotion context-insensitivity / Jonathan Rottenberg, Christine Vaughan -- Emotion regulation and the anxiety disorders : adopting a self-regulation perspective / Thomas L. Rodebaugh, Richard G. Heimberg -- The clinical assessment and treatment of trauma-related self and affect dysregulation / Annemiek van Dijke -- Emotional inhibition, health, gender, and eating disorders : the role of (over) sensitivity to others / Marrie H.J. Bekker, Sonja T.P. Spoor -- Emotional competence and health in children / Carolien Rieffe, Mark Meerum Terwogt, Francine C. Jellesma -- Crying in psychotherapy : its meaning, assessment, and management based on attachment theory / Judith K. Nelson -- Expressive writing in the clinical context / Joshua M. Smyth, Deborah Nazarian, Danielle Arigo -- Writing for all, for some, or for no one? Some thoughts on the applications and evaluations of the writing technique / Luigi Solano, Maria Bonadies, Michela Di Trani.
  • 2013
    Marian Allsopp.
    "Marion Allsopp maps the emergence of a powerful psycho-social idea out of its historical and social circumstances, as the concept of injury or trauma has moved, over the twentieth century, from the description of a physical, visible lesion to a more abstract, psychic harm -- often thought of as an 'invisible wound'. She looks at examples of this 'inward turn' in different academic, professional and administrative contexts in the Anglophone world: US psychiatry; UK tort law; Child Protection and the psychological/psychotherapeutic world of attachment theory, both of which span the Atlantic. How have 'psy' academics and professionals, with all their varied theories and techniques of intervention, contributed to the making of new ideas about an injured inner space? How have they explored the psychic interior; what are the emerging fields of knowledge and political conditions which facilitated the growth of this problem category of psychic harm, creating new claims to injury and new forms of state and non-state power? This mapping is not a description of a march towards some inexorable truth. On the contrary, by showing the ideas ' historical or contingent nature, it questions the inevitability of our 21st century present, in which the concept of psychological harm is so pervasive and taken for granted." -- [Publisher-supplied data]
  • 2014 Springer
    Giovanni Corona, Emmanuele A. Jannini, Mario Maggi, editors.
    This book describes different kinds of psychological, physical and sexual maltreatment and explains their possible consequences, especially as regards quality of life, psychopathology and sexual life. The focus is specifically on the victims of abuse, who are among the more frail and vulnerable members ofsociety. The book examines the impacts of maltreatment of both children and social minorities, such as homosexuals and gender dysphoric individuals or those affected by disabilities and describes skills that are of value in supporting victims of maltreatment and preventing discrimination. The work will be useful to sexual medicine specialists, medical doctors, psychologists and psychiatrists, as well as graduate students in these disciplines. By fostering a better understanding of discrimination triggers and effects, it will help clinicians to provide improved support through the tailoring of therapies to the needs of maltreated individuals.
  • 2010 Springer
    Sabine Roeser, editor.
    Moral heuristics and risk / Cass R. Sunstein -- Here's how I feel : don't trust your feelings! / Ronald de Sousa -- If I look at the mass I will never act : psychic numbing and genocide / Paul Slovic -- Marketing risk : emotional appeals can promote the mindless acceptance of risk / Ross Buck and Whitney A. Davis -- Emotions as aids and obstacles in thinking about risky technologies / Dylan Evans -- Risk assessment as virtue / Sabine Döring and Fritz Feger -- Emotions and judgments about risk / Robert C. Roberts -- The moral risks of risky technologies / Peter Goldie -- Ethical imagination : broadening laboratory deliberations / Simone van der Burg -- Emotion in risk regulation : competing theories / Dan M. Kahan -- Emotions within the bounds of pure reason : emotionality and rationality in the acceptance of technological risks / Dieter Birnbacher -- Emotions involved in risk perception : from sociological and psychogical risk studies towards a neosentimentalist meta-ethics / Felicitas Kraemer -- Risk emotions and risk judgments : passive bodily experience and active moral reasoning in judgmental constellations / Mark Coecklebergh -- Emotional reflection about risks / Sabine Roeser.
  • 2009 Springer
    Birgitt Rottger-Rossler, Hans J. Markowitsch, editors.
    Prologue -- Concepts and approaches -- Empirical studies: Shame and pride : prototypical emotions between biology and culture.
  • 2010
    Siddhartha Mukherjee.
    Status: Not Checked OutLane Catalog Record
    "Of blacke cholor, without boyling" -- An impatient war -- "Will you turn me out if I can't get better?" -- Prevention is the cure -- "A distorted version of our normal selves" -- The fruits of long endeavors -- Atossa's war.
  • 2010 Kais Fam Found
    The Kaiser Family Foundation, Health Research and Educational Trust, [and the National Opinion Research Center].
    "This annual survey of employers provides a detailed look at trends in employer-sponsored health coverage, including premiums, employee contributions, cost-sharing provisions, and other relevant information. The survey continued to document the prevalence of high-deductible health plans associated with a savings option and included questions on wellness benefits and health risk assessments. The 2010 survey included 3,143 randomly selected public and private firms with three or more employees (2,046 of which responded to the full survey and 1,097 of which responded to an additional question about offering coverage). Researchers at the Kaiser Family Foundation, the National Opinion Research Center at the University of Chicago, and Health Research & Educational Trust designed and analyzed the survey"--Website.
    Also available: Print – 2010
  • 2015 Cambridge
    Andrea Pilkington, MRCOG, PG Dip Med Ed, Trainee in Obstetrics and Gynaecology, North West Deanery, UK, Amitabha Majumdar, MRCOG, Consultant in Obstetrics and Gynaecology, University Hospital South Manchester, UK.
    Introduction -- Obstetrics EMQs -- Gynaecology EMQs -- Miscellaneous EMQs -- Answers.
  • 2012 Future Med
    editors, Steven G. Reed, Christopher B. Fox, Darrick Carter.
    Emulsion-based vaccine adjuvants / Christopher Fox, Darrick Carter & Steven G. Reed -- MF59® : an oil-in-water adjuvant / Jennifer Whitaker, Nadine Rouphael & Mark J. Mulligan -- AS03 adjuvant / Woolf T. Walker & Saul N. Faust -- Innovations in emulsion technology / Christopher B. Fox, Darrick Carter, Susan L. Baldwin, & Steven G. Reed -- Index.
  • 2006 CRCnetBASE
    edited by Johan Sjoblom.
  • 2011
    Ivan S. Ufimtsev.
    The role of atomistic modeling of molecules and organic compounds in biology and pharmaceutical research is constantly increasing, providing insights on chemical and biological phenomena at the highest resolution. To achieve relevant results, however, computational biology has to deal with systems containing at least 1000 atoms. Such big molecules cause large computational demands and impose limitations on the level of theory used to describe molecular interactions. Classical molecular mechanics based on various empirical relationships has become a workhorse of computational biology, as a practical compromise between accuracy and computational cost. Several decades of classical force field development have seen many successes. Nevertheless, more accurate treatment of bio-molecules from first principles is highly desirable. Hartree-Fock (HF) and density functional theory (DFT) are two low-level ab initio methods that provide sufficient accuracy to interpret experimental data. They are therefore the methods of choice to study large biological systems. Recently DFT has been applied to calculate single point energy of a solvated Rubredoxin protein. The system contained 2825 atoms and required more than two hours on a supercomputer with 8196 parallel cores. This study clearly demonstrates the scale of problems one has to tackle in first principles calculations of biologically relevant systems. Dynamical simulations requiring thousands of single point energy and force evaluations therefore appear to be completely out of reach. This fact has essentially prohibited the use of first principles methods for many important biological systems. Fortunately, the computer industry is evolving quickly and novel computing architectures such as graphical processing units (GPUs) are emerging. The GPU is an indispensable part any modern desktop computer. It is special purpose hardware responsible for graphics processing. Most problems in computer graphics are embarrassingly parallel, meaning they can be split into a large number of smaller subproblems that can be solved in parallel. This fact has guided GPU development for more than a decade; and modern GPUs evolved into a massively parallel computing v architecture containing hundreds of basic computational units, which all together can perform trillions of arithmetic operations per second. The large computational performance and low price of consumer graphics cards makes it tempting to consider using them for computationally intensive general purpose computing. This fact was recognized long ago and several groups of enthusiasts attempted to use GPUs for non-graphics computing in the early 2000's. One of the few successes from these attempts is now known as Folding@Home. These early attempts were primarily stymied by three major problems: lack of adequate development frameworks, limited precision available on GPUs, and the difficulty of mapping existing algorithms onto the new architecture. The two former impediments have been recently alleviated by the introduction of efficient GPU programming toolkits such as CUDA and the latest generation of graphics cards supporting full double precision arithmetic operations in hardware. These advances led to an explosion of interest in general purpose GPU computing and led to the development of many GPU-based high performance applications in various fields such as classical molecular dynamics, magnetic resonance imaging, and computational fluid dynamics. Most of the projects, however, lie far outside of quantum chemistry which is likely caused by the complexity of quantum chemistry algorithms and the associated difficulty of mapping them onto the GPU architecture. Various specific features of the hardware require complete redesign of conventional HF and DFT algorithms in order to fully benefit from the large computational performance of GPUs. We have successfully solved this problem and implemented the new algorithms in TeraChem, a high performance general purpose quantum chemistry package designed for graphical processing units from the ground up. Using TeraChem, we performed the first ab initio molecular dynamics simulation of an entire Bovine pancreatic trypsin inhibitor (BPTI) protein for tens of picoseconds on a desktop workstation with eight GPUs operating in parallel. Coincidently, this was also the first protein ever simulated on a computer using the classical molecular mechanics approach. BPTI binds to trypsin with a binding free energy of approximately 20 kcal/mol, making BPTI one of the strongest non-covalent binders. It vi is even more remarkable that a single BPTI amino acid LYS15 contributes half of the binding free energy by forming a salt bridge with one of the trypsin's negatively charged residues inside the binding pocket. In fact, the LYS15's contribution to the overall binding energy is approximately twice as large as what would be expected based on experimental measurements of salt bridge interactions in other proteins. Our simulation of BPTI demonstrated that substantial charge transfer occurs at the proteinwater interface, where between 2.0 and 3.5 electrons are transferred from the interfacial water to the protein. This effect decreases the net protein charge from +6e as observed in gas-phase experiments to +4e or less. We demonstrate how this effect may explain the unusual binding affinity of the LYS15 amino acid.
  • v. 1-2., 1983-
    technical editor, Luigi Parmeggiani.
    Status: Not Checked OutLane Catalog Record
    v. 1. A-K -- v. 2. L-Z.
  • 2008 Springer
    Helaine Selin (ed.).
    v. 1. A-K -- v. 2. L-Z.
  • 2006
    Richard Schulz, editor-in-chief ; Linda S. Noelker, Kenneth Rockwood, Richard L. Sprott.
    Status: Not Checked OutLane Catalog Record
    v. 1. A-K -- v. 2. L-Z.
  • 2008 Springer
    Sana Loue, Martha Sajatovic (eds.) ; core editors, Siran Koroukian ... [et al.].
    Foundation topics. Biology of aging / Teresa Dolinar. The history and demography of aging in the United States / Gail E. Souare, Linda S. Lloyd. Cultural diversity among elders in the US : meeting the challenge of the ethnogeriatric imperative / Gwen Yeo. Legal aspects of aging / Janet L. Lowder ... [et al.] The participation of cognitivelly impaired elderly in research / Sana Loue -- Topics in aging and public health.
  • 2007 Springer
    edited by M.Y. Kao.
  • 2008 ebrary, Limited to 1 simultaneous user
    edited by Paul Keyser and Georgia L. Irby-Massie.
    This is the first comprehensive English language work to assemble information covering all Greek and Latin natural science, from its beginnings with Thales through the end of the Late Antiquity with Isidore of Seville and Paulos of Aigina. A team of over 100 of the world's experts in the field have compiled almost 1600 entries - 244 of those describing figures that are not mentioned in any other reference work - resulting in a unique and hugely ambitious resource which will prove indispensable for anyone seeking the details of the history of ancient science.
  • 2013 Springer
    Marc D. Gellman, editor ; J. Rick Turner, co-editor.
    "This encyclopedia advances the understanding of behavioral medicine principles and clinical applications among researchers and practitioners in medicine, psychology, public health, epidemiology, nursing, and social work. In addition, the encyclopedia provides useful synergies for sociologists, anthropologists, and undergraduates with some interest in the interface of human health and behavior. Areas covered include quality of life and lifespan issues; population, health policy, and advocacy issues; health promotion and disease prevention; behavioral care in all types of settings; biological, psychological, and person factors in health behavior change; professional development and practice-related issues; and much more. This encyclopedia is the first resource to which readers turn for factual, relevant, and comprehensive information to aid in delivering the highest quality services."--Publisher's website.
  • 2010 ScienceDirect
    editors-in-chief, George F. Koob, Michel Le Moal, Richard F. Thompson.
    Subject Classification: -- Addiction -- Animal Models of Behavior -- Behavioral Genetics -- Brain Aging -- Brain Structure and Function -- Cognitive Neuroscience -- Disease and Dysfunction -- Developmental Biology -- Emotion and Emotional Behavior -- Ethology and Neuroethology -- Evolution and Comparative Biology -- History -- Language and Communication -- Learning and Memory -- Molecular Neurobiology -- Motivation and Reward -- Motor Systems and Motor Control -- Neuroplasticity -- Psychoneuroendocrinology -- Reproductive , Parental and Sexual behavior -- Sensation and Perception -- Sleeping, Waking and Arousal -- Social Behavior/Cognition -- Stress.
  • 2005- Wiley
    [editors-in-chief], Peter Armitage, Theodore Colton.
    The Encyclopedia of Biostatistics, 2nd Edition offers a reference to support the development and use of statistical methods for addressing the problems and critical issues that confront scientists, practitioners and policy makers engaged in the life and medical sciences.
  • 2009 Springer
    Manfred Schwab (ed.).
  • 2012 Springer
    Manfred Schwab, editor.
    V. 1. A-B -- v. 2. C -- v. 3. D-G -- v. 4. H-L -- v. 5. M-O -- v. 6. P-R -- v. 7. S-Z.
  • 2011 Springer
    Sam Goldstein, Jack A. Naglieri, (eds.).
    This major reference work will break new ground as an electronic resource for students, educators, researchers and professionals. Encyclopedic in breath Child Behavior and Development will serve as a reference repository of knowledge in the field as well as a frequently updated conduit of new knowledge long before such information trickles down from research to standard textbooks. Child Behavior and Development will consist of three volumes divided by the major conceptual areas of child development: Learning, Behavior, and Emotions. Taking advantage of the techniques offered by the electronic medium, Child Behavior and Development will offer an extensive cross referencing system facilitating search and retrieval of information.
  • 2011 Springer
    Jeffrey S. Kreutzer, John DeLuca, Bruce Caplan, editors.
    v. 1. A-C -- v. 2. D-K -- v. 3. L-P -- v. 4. Q-Z.
  • 1998 Wiley
    editor-in-chief, Paul von Ragué Schleyer.
  • 2008 Springer
    Albert L. Baert (ed.).
    v. 1. A-K -- v. 2. L-Z.
  • 2012 Springer
    Frank C. Mooren, ed.
    The Encyclopedia of Exercise Medicine is intelligently structured, easy accessible and user-friendly: A-Z format, clear, concise language and uniform essay structure as well as extensive cross references between keywords and related articles enables efficient searches in a user-friendly manner both for experts and newcomers. It is intended to be a comprehensive up-to-date data base on the adaptation of the human body to exercise and on the therapeutic use of exercise with up to 2,000 keywords. It covers all aspects within the full range of modern exercise medicine of each particular scientific discipline (cancer, parasitology, aging, etc.). This includes information on methodological approaches to measuring the principle components of motor fitness, and practical aspects of their enhancement by trainings regimes as well as by nutrition and the application of drugs. Such a wide range of entries, all written by leading experts in their respective fields, will therefore address both the basic/clinical scientist as well as the practitioner. Moreover, the Encyclopedia of Exercise Medicine is aimed at people in related fields, health care professionals, physiotherapists, trainers, students, informed athletes and interested laypersons. It is available both in print and as a fully searchable and hyperlinked electronic online edition.
  • 2005 Wiley
    SU Catalog (SearchWorks) Click LINK above for Print location/circulation status.
    editor, Lynn B. Jorde.
    v. 1. Genetics -- v. 2. Genetics -- v. 3. Genomics -- v. 4. Genomics -- v. 5. Proteomics -- v. 6. Proteomics -- v. 7. Bioinformatics -- v. 8. Bioinformatics.
  • 2008 Springer
    George P. Rédei.
    v. 1. A-L -- v. 2. M-Z.
  • v. 1-2, 2007.
    edited by James E. Birren.
    Status: Not Checked OutLane Catalog Record
  • 2011 Springer
    M. Gabriel Khan ; with a foreword by Christopher P. Cannon.
  • 2006 ScienceDirect
    M. Gabriel Khan.
    Aging and the heart -- Alcohol and the heart -- Altitude and pulmonary edema -- Anatomy of the heart and circulation -- Anderson-Fabry disease -- Anemia and the heart -- Aneurysm -- Angina -- Angioplasty/coronary balloon -- Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers -- Antihistamines -- Antioxidants -- Antiphospholipid antibody syndrome -- Antiplatelet agents -- Arginine and the heart -- Arrhythmias/palpitations -- Arteriosclerosis -- Artificial heart -- Aspirin for heart disease -- Atherosclerosis/atheroma -- Athletes and sudden cardiac death -- Atrial fibrillation -- Atrial septal defect -- B-type natriuretic peptide -- Beriberi heart disease -- Beta-blockers -- Blood clots -- Blood pressure -- Brugada syndrome -- Bundle branch block -- Caffeine and the heart -- Calcium antagonists -- Carcinoid heart disease -- Cardiogenic shock -- Cardiomyopathy -- Cardiopulmonary resuscitation (CPR) -- Chagas disease -- Chelation and heart disease -- Chemotherapy-induced heart disease -- Cholesterol -- Coenzyme Q10 -- Congenital heart disease -- Contraception and cardiovascular disease -- Coronary artery bypass surgery -- C-reactive protein and the heart -- Cytochrome P-450 -- Deep vein thrombosis -- Depression and the heart -- Diabetes and cardiovascular disease -- Diets and heart disease -- Diuretics -- Down syndrome -- Dyslipidemia -- Echocardiography -- Effects of smoking and heart disease -- Electrocardiography -- Embryology -- Endocarditis -- Endocrine disorders and the heart -- Erectile dysfunction and the heart -- Exercise and the heart -- Gene therapy -- Heart attacks -- Heart failure -- Hemochromatosis -- Herbal, dietary supplements, and cardiovascular disease -- HIV and the heart -- Homocysteine and cardiovascular disease -- Hypertension -- Hypertrophy of the heart -- Kawasaki heart disease -- Miscellaneous disorders -- Murmurs and heart disease -- Nonsteroidal anti-inflammatory drugs -- Obesity and heart disease -- Pacemakers -- Patent foramen ovale -- Pericarditis and myocarditis -- Pulmonary arterial hypertension -- Pulmonary embolism -- Race and cardiovascular disease -- Sleep and the heart -- Stents -- Stress and heart disease -- Stroke/cerebrovascular accident -- Syncope -- Tests for heart diseases -- Thyroid heart disease -- Valve diseases -- Ventricular fibrillation -- Women and heart disease.
  • 2012 Springer
    Sana Loue and Martha Sajatovic (eds.).
    Part 1. Immigrant Health Overview Chapters -- Immigration in the Global Context / Bettina Rausa, Linda S. Lloyd -- Immigration Processes and Health in the U.S.: A Brief History / Sana Loue -- Alternative and Complementary Medicine / Brenda L. Lovell, Jamileh Daneshnia, Christopher J. Fries -- Culture-Specific Diagnoses / Delaney Smith, Tara Mayes, Riley Smith -- Health Determinants / M. David Low, Barbara J. Low -- Occupational and Environmental Health / Doug Brugge, C. Eduardo Siqueira -- Methodological Issues in Immigrant Health Research / Patrick J. M. Murphy, Irin Rachel Allen , Mo-Kyung Sin -- Ethical Issues in Research with Immigrants and Refugees / Sana Loue -- Ethical Issues in the Clinical Context / Beatrice Gabriela Ioan -- Part 2. Immigrant Health Topics A-Z.
  • 2003 ScienceDirect
    editor-in-chief, Hossein Bidgoli.
  • 2012 Springer
    edited by Jean-Louis Vincent, Jesse B. Hall.
    "The aim of this comprehensive encyclopedia is to provide detailed information on intensive care medicine contributing to the broad field of emergency medicine. Entries A - Z covering the following disciplines: neurologic problems, respiratory disorders, cardiovascular disorders, gastrointestinal disorders, nutrition therapy, metabolic disorders, renal disorders, infectious diseases, hematologic disorders, special populations, emergency medicine, trauma, ICU procedures, special issues."--Publisher.
  • Wiley
    A fully searchable, working editorial site of articles by scientists and scientific historians in the fields of biochemistry and physiology, cell biology, developmental biology, ecology, evolution, genetics, immunology, molecular biology, neuroscience, microbiology and virology, plant science, structural biology, and science and society.
  • 2006, 2010.
    John G. Webster, editor in chief.
  • 2014 Springer
    Ian R Mackay, Noel R Rose, editors-in-chief ; Dennis K Ledford, Richard F. Lockey editors.
  • 2014 Springer
    Ian MacKay, Noel R. Rose, editors-in-chief ; Betty Diamond, Anne Davidson, editors.
  • 2013 Springer
    edited by Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov.
    In biochemistry, a metalloprotein is a generic term for a protein that contains a metal cofactor. The metal may be an isolated ion or may be coordinated with a nonprotein organic compound, such as the porphyrin found in hemoproteins. In some cases, the metal is co-coordinated with a side chain of the protein and an inorganic nonmetallic ion. This kind of protein-metal-nonmetal structure is seen in iron-sulfur clusters Metalloproteins deals with all aspects related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The biological roles of metal cations and metal-binding proteins are endless. They are involved in all crucial cellular activities. Many pathological conditions are related to the problematic metal metabolism. Research in metalloprotein-related topics is therefore rapidly growing, and different aspects of metal-binding proteins progressively enter curricula at Universities and even at the High School level on occasion. However, no key resource providing basic, but comprehensible knowledge on this rapidly expanding field exists. The Encyclopedia of Metalloproteins aims to bridge this gap, and will attempt to cover various aspects of metalloprotein/metalloproteomics and will deal with the different issues related to the intracellular and extracellular metal-binding proteins, including their structures, properties and functions. The goal is to cover exhaustively all catalytically and biologically crucial metal ions and to find at least one interacting protein for other metal ions. The Encyclopedia of Metalloproteins will provide a key resource for advanced undergraduate and graduate students, researchers, instructors, and professors interested in protein science, biochemistry, cell biology, and genetics.
  • 2009 ScienceDirect
    editor-in-chief, Moselio Schaechter.
    Subject Classification: -- Applied Microbiology: Agro/Food -- Applied Microbiology: Industrial -- Archaea -- Bacteria -- Cell Structure Chemical Composition -- Environmental Microbiology and Ecology -- Evolution and Systematics -- Fungi -- Genetics, Genomics -- History and Culture, (and Biographies) -- Mutualism and Commensalism -- Pathogenesis -- Physiology -- Protists -- Public Issues -- Techniques -- Viruses.
  • 2009 Springer
    Florian Lang (ed.).
  • 2009 Springer
    edited by Marc D. Binder, Nobutaka Hirokawa and Uwe Windhorst (eds.).
  • 2009 ScienceDirect
    editor-in-chief, Larry R. Squire
    "Explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, psychiatry and other related areas of neuroscience"--About page.
  • 2006
    Joyce J. Fitzpatrick, editor-in-chief ; Meredith Wallace, associate editor.
    Status: Not Checked OutLane Catalog Record
  • 2013 Springer
    edited by Stilianos E. Kountakis.
    General Otolaryngology -- Pediatric Otolaryngology -- Head and Neck Surgery -- Otology-Neurotology -- Plastic and Reconstructive Surgery.
  • 2013 Springer
    edited by Robert F. Schmidt, Gerald F. Gebhart.
    This is the most comprehensive overview available anywhere on the broad, multi-faceted and complex topic of pain and the rapidly evolving scientific and medical disciplines that seek to understand, assess and treat pain. The second edition of theEncyclopedia of Pain is fully updated andhas been expanded by over 100 new essays. It includes more than 3,000 entries and provides clear, detailed and up-to-date coverage of the current state of research, and treatment of pain. In addition, detailed essays provide in-depth information on all aspects of nociception and pain, including substrates, causes, pathophysiology, symptoms and signs, diagnoses and treatment. More than 600 color figures enhance understanding of this too-little-understood topic. Solidly structured and inclusive, this reference is an invaluable tool for clinical scientists and practitioners in academia, health care and industry, as well as students, teachers and interested laypersons.
  • 2007 Springer
    [Robert F. Schmidt, William D. Willis, editors].
    v. 1. A-G -- v. 2. H-O -- v. 3. P-Z.
  • 2008 Springer
    Heinz Mehlhorn (ed.) ; with contributions by H. Aspö̈ck ... [et al.].
    v. 1. A-M -- v. 2. N-Z.
  • v.1-4, 2014 Springer
    edited by Thomas P. Gullota, Martin Bloom.
    Public Health is one of the fastest growing university programs in the United States today. At the same time, the challenges that face the practitioner continue to grow and become more complex. This Encyclopedia of Primary Prevention and Health Promotion, 2nd ed covers more than 250 topics, taking a lifespan approach to the fields of public health and prevention. The encyclopedia is divided into four volumes: 1. Foundational Topics 2. Early Childhood and Childhood 3. Adolescence 4. Adulthood and Older Adulthood Within each volume, issues of illness prevention and health promotion (sometimes referred to as "positive psychology") are addressed in chapter-length entries arranged alphabetically. An international group of contributors synthesizes research focusing on improving the physical and mental health of the community as a whole. Each entry will have a structured format: Introduction, Definition of Terms, Prevalence, Theories, Empirical Studies, and Strategies (What Works, What Is Promising, What Doesn't Work). Each entry concludes with a look ahead to the coming decades of Public Health - what are the next steps to primary prevention and health promotion - and a "See Also" box recommending books, films, or articles by the editors for further reading. The encyclopedia is designed for practitioners, students, and researchers working in prevention, public health, and psychology. It will also serve as reference for practitioners in sociology, social work, nursing and medicine. The second edition more than doubles the number of entries in the first edition by adding entries focusing on gender, African American and Latino issues, social support, social and emotional learning, and physical health and disease. All entries from the first edition will be rewritten and expanded, reflecting the most up to date thinking in the field.
  • 2010 Springer
    David A. Leeming, Kathryn Madden, Stanton Marlan (eds.).
    Offers a definitive and intellectually rigorous collection of psychological interpretations of the stories, rituals, motifs, symbols, doctrines, dogmas, and experiences of the world's religious and mythological traditions.
  • 2010 Springer
    edited by Ian P. Stolerman.
  • 2008 Springer
    edited by Wilhelm Kirch.
  • 2013 Springer
    Luther W. Brady and Theodore E. Yaeger (eds.).
    SECTION I: SCIENTIFIC FOUNDATIONS OF RADIATION ONCOLOGY -- Part A: Radiobiology -- Part B: Physics -- SECTION II: Techniques and Modalities -- SECTION III: DISEASE SITES -- Part A: Central Nervous System Tumors Overview -- Part B: Head and Neck Tumors Overview -- Part C: Thoracic Neoplams Overview -- Part D: Gastrointestinal Tumors Overview -- Part E: Genitourinary Tumors Overview -- Part F: Gynecologic Tumors Overview -- Part G: Breast Cancer Overview -- Part H: Sarcoma and Benign Disease -- Part I: Childhood Cancers Overview -- Part J: Lymphoma & Hematologic Malignancies Overview.
  • 2011 Springer
    W. Wolfgang Fleischhacker, Ian P. Stolerman (eds.).
    Key Essays: Active Avoidance / Marie-Louise G. Wadenberg -- Aggressive Behavior: Clinical Aspects / Emil F. Coccaro, -- Aminergic Hypothesis for Schizophrenia / Hiroyuki Uchida and Shitij Kapur -- Animal Models for Psychiatric States / Paul Willner -- Antipsychotic Drugs / W. Wolfgang Fleischhacker -- Anti-Parkinson Drugs / Joseph H. Friedman -- Antipsychotic Medication: Future Prospects / Seiya Miyamoto -- Cognitive Behavioral Therapy for People with Schizophrenia / Gillian Haddock -- Cognitive Remediation in Schizophrenia Patients / Alice Medalia and Alice Saperstein -- Delayed Onset of Drug Effects / Stefan Leucht -- Delusional Disorder / Istvan Bitter -- Dissociative Anesthetics / Anthony Absalom and David Menon -- Family Based Approaches for Schizophrenia Patients / Andrea Fiorillo and Silvana Galderisi -- First-Generation Antipsychotics / Cyril Höschl -- Hallucinations / Eileen M. Joyce -- Hallucinogen / Abuse and Dependence / John H. Halpern, Pedro E. Huertas, Joji Suzuki, and Torsten Passie -- Neurotoxicity and Schizophrenia / Heleen B. M. Boos, H. D. Postma, and Wiepke Cahn -- Pediatric Schizophrenia / Christoph U. Correl -- Pharmacogenetics of Antipsychotic Drug Response in Schizophrenia / Eva J. Brandl and Daniel J. Müller -- Pharmacogenetics of Drug Side Effects and Safety / Anil K. Malhotra and Todd Lencz -- Postpsychotic Depressive Disorder of Schizophrenia / Samuel G. Siris -- Pre-psychotic States and Prodromal Symptoms / Patrick D. Mcgorry, Alison R. Yung -- Psychoeducation in the Management of Schizophrenia / Werner Kissing and Gabriele Pitschel-Walz -- Rating Scales and Diagnostic Schemata / David V. Sheehan and Kathy H. Sheehan -- Rehabilitation in Schizophrenia / Wulf Rössler and Andreas Marneros -- Schizophrenia / Alex Hofer -- Second and Third Generation Antipsychotics / Gary Remington.
  • 2012 Springer
    Sangdun Choi, editor.
  • Wiley
    Reference tool covering statistics, probability theory, biostatistics, quality control, and economics with emphasis in applications of statistical methods in sociology, engineering, computer science, biomedicine, psychology, survey methodology, and other client disciplines.
  • v. 1-6, 2011 Springer
    v. 2, 2011 Springer
    v. 3, 2011 Springer
    v. 4, 2011 Springer
    v. 5, 2011 Springer
    v. 6, 2011 Springer
    Jiaju Zhou, Guirong Xie, Xinjian Yan.
    v. 1. Isolated compounds A-C -- v. 2. Isolated compunds D-G -- v. 3. Isolated compunds H-M -- v. 4. Isolated compunds N-S -- v. 4. Isolated compunds N-S -- v. 5. Isolated compunds T-Z, references, TCM plants and congeners -- v. 6. Indexes.
  • 2015 Springer
    Peter J. Papadakos, Mark L. Gestring, editors.
    From the contents: Overview of general trauma care. Injury epidemiology and control. Trauma system development and design. Injury scoring. Trauma outcome measures. Prehospital care of the trauma patient -- Early evaluation and management of the trauma patient. Initial assessment of the injured patient. Airway management in the trauma patient. Blood product utilization and resuscitation strategies following injury. Medications vital to trauma resuscitation. Role of ED thoracotomy -- Organ systems approach: Head. Neck. Chest. Abdomen. Urological. Vascular. Musculoskeletal. Specific considerations in trauma care: Pediatric trauma. Trauma in the elderly. Trauma in pregnancy. Combat casualty care. Burn injury -- Imaging in the trauma patient. Anesthesia management in trauma. Ethical issues in trauma care. Disaster and mass-casualty care. Blast injury. Rehabilitation: Brain injury rehabilitation. Rehabilitation following traumatic injury -- Complications in trauma care -- Critical care for the trauma patient.
  • 2007 CRCnetBASE
    Alan E. Comyns.
  • 2006 Springer
    Detlev Ganten, Klaus Ruckpaul (eds.).
    v. 1. A-L -- v. 2. M-Z.
  • 2005 Springer
    Hans-Werner Vohr (ed.).
  • 2012
    David B. Agus with Kristin Loberg.
    "From one of the world's foremost physicians and researchers, a monumental work that radically redefines our conventional conceptions of health and illness to offer new methods for living a long, healthy life. After considering the discoveries that have led to progress in treating some diseases, Dr. David B. Agus asked an essential question: Why aren't we better at curing illnesses like cancer? Based on his groundbreaking research and the clinical trials he has conducted at the nation's leading medical centers, he came to the realization that we've been approaching medicine from a faulty perspective, and the best way to prevent and combat maladies like cancer, heart disease, autoimmune disorders, and neurodegeneration is to first embrace a totally new view of the human body. What Is Health? asks readers to reconsider everything they think they know about health--and give up believing many myths that may actually be causing them harm and decreasing longevity. These myths revolve around a spectrum of misconceptions, from the benefits of vitamins and supplements to the role of DNA in one's fate. In attempting to reduce our understanding of ailments to a mutation, germ, or deficiency, Dr. Agus proves we have forgotten that the body is a complex system. He presents a systemic picture of the body's vast mechanisms that drive it either toward or away from sickness, empowering readers to take charge of their individual health in very personal, customized ways they've never imagined before. Along the way, Dr. Agus offers insights and access to breathtaking and powerful new technologies that promise to transform medicine in our generation. He also shows that there is no "right" answer in health decisions. This is a radically different approach that will not only change how we care for ourselves, but also how we develop the next generation of treatments and cures. What Is Health? represents a dramatic departure from orthodox thinking that promises to revolutionize our quest for long, healthy lives"-- Provided by publisher.
  • 2013 Springer
    David Oliver, editor.
    People with advancing neurological disease face increasing physical symptoms, along with psychosocial and spiritual issues affecting both themselves and their families and carers. There is increasing awareness that the end of life in neurological disease can be anticipated and recognised, taking into account certain key features of disease progression, and the associated issues can be addressed. The individual can prepare for future changes in their health, and be in a stronger position to influence or direct the care they receive. End of Life Care in Neurological Disease encourages health and social care professionals to become closely involved in the care of these people and their families, to maintain and maximise quality of life and plan ahead. This book addresses the principles and practice of end of life care for neurological disease, is written with a clinical, multidisciplinary focus, and is enriched with detailed case studies. This book is an accessible text for the multidisciplinary team in specialist palliative care, and will also be of interest to healthcare professionals in neurological services, including neurologists and neurology specialist nurses, rehabilitation services, general practitioners and community nurses. As care professionals, we are in a powerful position to help those who are living with advanced neurological disease and improve their quality of life and death.
  • 2006
    Andy Kessler.
    Status: Not Checked OutLane Catalog Record
    Chapter 13. Meeting Gary Glazer.
  • 2013
    John Rhodes.
    "At the turn of the twentieth century, smallpox claimed the lives of two million people per year. By 1979, the disease had been eradicated and victory was declared across the globe. Yet the story of smallpox remains the exception, as today a host of deadly contagions, from polio to AIDS, continue to threaten human health around the world. Spanning three centuries, The End of Plagues weaves together the discovery of vaccination, the birth and growth of immunology, and the fight to eradicate the world's most feared diseases. From Edward Jenner's discovery of vaccination in 1796, to the early nineteenth-century foundling voyages in which chains of orphans, vaccinated one by one, were sent to colonies around the globe, to the development of polio vaccines and the stockpiling of smallpox as a biological weapon in the Cold War, world-renown immunologist John Rhodes charts our fight against these plagues, and shows how vaccinations gave humanity the upper hand. Today, aid groups including the Bill and Melinda Gates Foundation and the World Health Organization have made the eradication of polio a priority, and Rhodes takes us behind the scenes to witness the hard-fought battles of scientist, philanthropists, volunteers, and more, and how soon we may be celebrating the eradication of a second infectious disease, polio"--Provided by publisher.
  • 2011 Springer
    John Dennison, Charles Oxnard, Peter Obendorf.
  • 2009 Springer
    Armin Ernst, Felix J.F. Herth, editors.
  • 2013 Springer
    Elisabeth J. Van Bockstaele, editor.
    Endocannabinoids and monoamines: modulating the modulators -- Endocannabinoid-mediated synaptic plasticity -- Current cannabinoid receptor nomenclature and pharmacological principles -- Cue-elicited craving for cannabis activates the reward neurocircuitry associated with the neuropathology of addiction -- Cannabinoid modulation of dopaminergic circuits in neurodegenerative and neuropsychiatric disorders -- Pathophysiology of mood disorders and mechanisms of action of antidepressants and mood stabilizers -- Anatomical, biochemical and behavioral evidence for cannabinoid modulation of noradrenergic circuits: role of norepinephrine in cannabinoid-induced aversion -- Gender Disparity of Depression: The Role of Endocannabinoids and Noradrenergic Function -- Endocannabinoids, Monoamines and Stress -- Chronic effects of cannabinoid drugs on monoaminergic systems and the role of endocannabinoids and cannabinoid receptors in human brain disorders -- Endocannabinoid Signaling and the Regulation of the Serotonin System -- Modulation of serotonin firing activity through CB1 agonists and FAAH inhibitors -- Involvement of serotonergic system in cannabinoid analgesia -- Cannabinoids, monoamines, COMT and schizophrenia: pathobiological mechanisms in psychosis.
  • 2015 Springer
    Roger G. Pertwee, editor.
    There is currently considerable interest in the development of medicines that would enhance endocannabinoid-induced ℓ́ℓautoprotectionℓ́ℓ, for example through inhibition of endocannabinoid metabolizing enzymes or cellular uptake processes or that would oppose endocannabinoid-induced autoimpairment. This volume describes the physiology, pathophysiology and pharmacology of the endocannabinoid system and potential strategies for targeting this system in the clinic.
  • 2013 Springer
    Mary E. Abood, Roger G. Sorensen, Nephi Stella, editors.
    Part 1. Overview of Non-Cannabinoid Receptors -- Overview of Nonclassical Cannabinoid Receptors / Grzegorz Godlewski and George Kunos -- Overview of Non-CB1/CB2 Cannabinoid Receptors: Chemistry and Modeling / Evangelia Kotsikorou and Patricia Reggio -- Part 2. G-Protein Coupled Receptors -- GPR55 in the CNS / Hui-Chen Lu, Jane E. Lauckner, John W. Huffman and Ken Mackie -- The Role of GPR55 in Bone Biology / Lauren S. Whyte and Ruth A. Ross -- The Role of GPR55 in Cancer / Clara Andradas, María M. Caffarel, Eduardo Pérez-Gómez, Manuel Guzmán and Cristina Sánchez -- GPR18 and NAGly Signaling: New Members of the Endocannabinoid Family or Distant Cousins? / Douglas McHugh and Heather B. Bradshaw -- Cannabinoid Signaling Through Non-CB1R/Non-CB2R Targets in Microglia / Neta Rimmerman, Ewa Kozela, Rivka Levy, Zvi Vogel and Ana Juknat -- Part 3. Ion Channels -- Temperature-Sensitive Transient Receptor Potential Channels as Ionotropic Cannabinoid Receptors / Vincenzo Di Marzo and Luciano De Petrocellis -- Nonpsychoactive Cannabinoid Action on 5-HT3 and Glycine Receptors / Li Zhang and Wei Xiong -- Part 4. Transcription Factors -- Peroxisome Proliferator-Activated Receptors and Inflammation / James Burston and David Kendall -- Peroxisome Proliferator-Activated Nuclear Receptors and Drug Addiction / Paola Mascia, Gianluigi Tanda, Sevil Yasar, Stephen J. Heishman and Steven R. Goldberg -- Part 5. Conclusions/Therapeutic Potential -- Conclusions: Therapeutic Potential of Novel Cannabinoid Receptors / Mary E. Abood, Roger G. Sorensen and Nephi Stella.
  • 2006 CRCnetBASE
    edited by Emmanuel S. Onaivi, Takayuki Sugiura, Vincenzo di Marzo.
  • 2016 Springer
    Kwan-Leung Chan, John M. Embil, editors.
    Perspectives on the History of Endocarditis -- Pathologic Findings: Valvular Destruction, Perivalvular Abnormalities and Extracardiac Findings -- Changing populations: the elderly, injection drug users, health-care associated endocarditis and immunocompromised patients -- Microbiology of Infective Endocarditis and Microbiologic Diagnosis -- Prophylaxis of Endocarditis -- Diagonstic Approach to Endocarditis -- Role of Transthoracic and Transesophageal Echocardiography in the Management of Endocarditis -- Surgical Management: Indications, Timing and Surgical Techniques -- Treatment of Endocarditis -- Blood Culture Negative Endocarditis -- Prosthetic Valve Endocarditis & Cardiovascular Device Related Infections -- Pediatric Infective Endocarditis and Congenital Heart Disease -- Systemic Embolism in Endocarditis: Incidence, Risk Factors, Clinical -- Significance, and Treatment Strategies -- Neurological Complications of Endocarditis: Pathophysiologic -- Mechanisms and Management Issues.
  • 2006 Springer
    Kwan-Leung Chan and John M. Embil (eds.).
  • 2009 CRCnetBASE
    Robert F. Dons and Frank H. Wians Jr.
    This volume updates its classic predecessor in both content and format. Written by two of the respected authorities in diagnostic endocrinology, it includes detailed information on how to perform and interpret those laboratory test procedures used to confirm the clinical diagnosis of the majority of known endocrine disorders. Newly designed, it provides a standardized format that makes it easier to access complete information about the diagnosis, screening, and management of traditional and newly perceived endocrine disorders. It provides sample calculations to assist with complex formulas as well as ICD-9 codes for all procedures.
  • 2013 ClinicalKey
    Bruce A. White, Susan P. Porterfield.
    Introduction to the endocrine system -- Endocrine function of the gastrointestinal tract -- Energy metabolism -- Calcium and phosphate homeostasis -- Hypothalamus-pituitary complex -- The thyroid gland -- The adrenal gland -- Life cycle of the male and female reproductive system -- The male reproductive system -- The female reproductive system -- Fertilization, pregnancy, and lactation.
  • 2009 CRCnetBASE
    edited by James Devillers.
    In silico methods for modeling endocrine disruption / James Devillers -- Mechanisms of endocrine disruptions : a tentative overview / Jean-Marc Porcher, James Devillers, and Nathalie Marchand-Geneste -- Population dynamics modeling : a tool for environmental risk assessment of endocrine disrupting chemicals / Andrew R. Brown ... [et al.] -- Application of pharmacokinetic modeling to understand the mechanism of action of endocrine disrupting chemicals / James Devillers -- Comparative modeling review of nuclear hormone receptor superfamily / Nathalie Marchand-Geneste and James Devillers -- The U.S. Food and Drug Administration's (FDA) Endocrine Disruptor Knowledge Base (EDKB) : lessons learned in QSAR modeling and applications / Hong Fang ... [et al.] -- A structure-activity relationship (SAR) analysis for the identification of environmental estrogens : the categorical-SAR (cat-SAR) approach / Albert R. Cunningham ... [et al.] -- Kohonen and counterpropagation neural networks employed for modeling endocrine disruptors / Marjana Novič and Marjan Vračko -- Quantitative spectrometric data-activity relationships (QSDAR) models of endocrine disruptor binding activities / Richard D. Beger, Dan A. Buzatu, and Jon G. Wilkes -- Mechanism-based modeling of estrogen receptor binding affinity : a Common Reactivity Pattern (COREPA) implementation / Ovanes Mekenyan and Rossitsa Serafimova -- Molecular field analysis methods for modeling endocrine disruptors / Jean-Pierre Doucet and Annick Panaye -- Structure-activity modeling of a diverse set of androgen receptor ligands / James Devillers ... [et al.] -- SAR and QSAR analyses of substituted dibenzoylhydrazines for their mode of action as ecdysone agonists / Toshio Fujita and Yoshiaki Nakagawa -- e-Endocrine disrupting chemical databases for deriving SAR and QSAR models / Nathalie Marchand-Geneste ... [et al.].
  • 2012 Springer
    edited by Evanthia Diamanti-Kandarakis, Andrea C. Gore.
    1. Introduction to Endocrine Disruptors and Puberty / Evanthia Diamanti-Kandarakis and Andrea C. Gore -- pt. I. EDCs, Endocrine Systems, and Puberty -- 2. In Utero Exposure to Environmental Chemicals: Lessons from Maternal Cigarette Smoking and Its Effects on Gonad Development and Puberty / Rebecca McKinlay, Peter O'Shaughnessey, Richard M. Sharpe, and Paul A. Fowler -- 3. Reproductive Neuroendocrine Targets of Developmental Exposure to Endocrine Disruptors / Sarah M. Dickerson, Stephanie L. Cunningham, and Andrea C. Gore -- 4. Endocrine Disruptors and Puberty Disorders from Mice to Men (and Women) / Alberto Mantovani -- 5. Thyroid Hormone Regulation of Mammalian Reproductive Development and the Potential Impact of Endocrine-Disrupting Chemicals / Kara Renee Thoemke, Thomas William Bastian, and Grant Wesley Anderson -- pt. II. Developmental Exposure to Endocrine Disruptors and adverse reproductive outcomes -- 6. Developmental Exposure to Endocrine Disruptors and Ovarian Function / Evanthia Diamanti-Kandarakis, Eleni Palioura, Eleni A. Kandaraki -- 7. Developmental Exposure to Environmental Endocrine Disruptors and Adverse Effects on Mammary Gland Development / Suzanne E. Fenton, Lydia M. Beck, Aditi R. Borde, and Jennifer L. Rayner -- 8. Developmental Exposure to Endocrine Disruptors and Male Urogenital Tract Malformations / Mariana F. Fernandez and Nicolas Olea -- 9. EDC Exposures and the Development of Reproductive and Nonreproductive Behaviors / Craige C. Wrenn, Ashwini Mallappa, and Amy B. Wisniewski -- pt. III. Developmental Exposure to Endocrine Disruptors and Metabolic Disorders -- 10. Adipocytes as Target Cells for Endocrine Disruption / Amanda Janesick and Bruce Blumberg -- 11. Altered Glucose Homeostasis Resulting from Developmental Exposures to Endocrine Disruptors / Alan Schneyer and Melissa Brown -- 12. Developmental Exposure to Endocrine Disrupting Chemicals: Is There a Connection with Birth and Childhood Weights? / Elizabeth E. Hatch, Jessica W. Nelson, Rebecca Troisi, and Linda Titus -- pt. IV. EDCs and Human Health -- 13. The Impact of Endocrine Disruptors on Female Pubertal Timing / Jean-Pierre Bourguignon and Anne-Simone Parent -- 14. The Influence of Endocrine Disruptors on Male Pubertal Timing / Xiufeng Wu, Ningning Zhang, and Mary M. Lee -- 15. Secular Trends in Pubertal Timing: A Role for Environmental Chemical Exposure? / Vincent F. Garry and Peter Truran.
  • 2014 Wiley
    Sushil K. Khetan.
    Environmental endocrine disruptors -- Part I. Mechanisms of hormonal action and putative endocrine disruptors. Mechanisms of endocrine system function -- Environmental chemicals targeting estrogen signaling pathways -- Anti-androgenic chemicals -- Thyroid-disrupting chemicals -- Activators of PPAR, RXR, AhR, and steriodogenic factor 1 -- Effects of EDC mixtures -- Environmentally induced epigenetic modifications and transgenerational effects -- -- Part II. Removal mechanisms of EDCs through biotic and abiotic processes. Biodegradations and biotransformations of selected examples of EDCs -- Abiotic degradations / transformations of EDCs through oxidation processes -- -- Part III. Screening and testiing for potential EDCs, implications for water quality sustainability, policy and regulatory issues, and green chemistry principles in the design of safe chemicals and remediation of EDCs. Screening and testing programs for EDCs -- Trace contaminants : implications for water quality sustainability -- Policy and regulatory considerations for EDCs -- Green chemistry principles in the designing and screening for safe chemicals and remediation of EDCs.
  • 2014 Springer
    Lynn Loriaux, editor.
    Endocrine Emergencies: Recognition and Treatment offers a state-of-the-art update on the management of endocrine, diabetic, and metabolic emergencies. Developed by renowned experts, this comprehensive and easy to read title brings the field fully up to date, setting a high standard for diagnosis and treatment in each category. All chapters begin with a summary that presents, in concentrated form, what the physician needs to know to begin the evaluation and emergency treatment of the known endocrine emergencies. This is followed by an extended discussion of the pathophysiology that can be read after initial treatment has begun. Covering such areas as hypoglycemia, acute adrenal insufficiency, ovarian hyperstimulation syndrome, thyroid storm, and pituitary apoplexy, just to name several, Endocrine Emergencies: Recognition and Treatment is an invaluable, practical resource that will be of great interest to endocrinologists, internal medicine and emergency room physicians, fellows and residents.
  • 2012 Springer
    edited by Makoto Kuro-o.
    The Structural Biology of the FGF19 Subfamily / Andrew Beenken and Moosa Mohammadi -- Klotho and βKlotho / Makoto Kuro-o -- FGF23 and Syndromes of Abnormal Renal Phosphate Handling / Clemens Bergwitz and Harald Jüppner -- Evidence for FGF23 Involvement in a Bone-Kidney Axis Regulating Bone Mineralization and Systemic Phosphate and Vitamin D Homeostasis / Aline Martin and L. Darryl Quarles -- FGF23, Klotho and Vitamin D Interactions: What Have We Learned from In Vivo Mouse Genetics Studies? / M. Shawkat Razzaque -- FGF23 and the Parathyroid / Justin Silver and Tally Naveh-Many -- Regulation of Ion Channels by Secreted Klotho / Chou-Long Huang -- FGF23 in Chronic Kidney Disease / Patricia Wahl and Myles Wolf -- Secreted Klotho and Chronic Kidney Disease / Ming Chang Hu, Makoto Kuro-o and Orson W. Moe -- FGF23 as a Novel Therapeutic Target / Takashi Shimada and Seiji Fukumoto -- Physiology of FGF15/19 / Stacey A. Jones -- FGF19 and Cancer / Benjamin C. Lin and Luc R. Desnoyers -- Understanding the Structure-Function Relationship between FGF19 and Its Mitogenic and Metabolic Activities / Xinle Wu and Yang Li -- FGF21 as a Therapeutic Reagent / Yang Zhao, James D. Dunbar and Alexei Kharitonenkov.
    Also available: Print – 2012
  • 2013 Springer
    Christian A. Koch, George P. Chrousos, editors.
    Machine generated contents note: pt. I Adrenal Hypertension -- 1. Primary Aldosteronism: Progress in Diagnosis, Therapy, and Genetics / Franco Veglio -- 2. Syndromes of Mineralocorticoid Excess / Christian A. Koch -- 3. Hypertension in Patients with Cushing's Syndrome / George P. Chrousos -- 4. Primary Generalized Familial and Sporadic Glucocorticoid Resistance (Chrousos Syndrome) and Hypersensitivity / George P. Chrousos -- 5. Congenital Adrenal Hyperplasia / Deborah P. Merke -- 6. Adrenal Incidentalomas and Arterial Hypertension / George P. Chrousos -- 7. Pheochromocytoma: Unmasking the Chameleon / Karel Pacak -- pt. II Other Potential Causes of Endocrine Hypertension -- 8. Hypertension in Growth Hormone Excess and Deficiency / George R. Merriam -- 9. Primary Hyperparathyroidism and Hypertension / Shonni J. Silverberg -- 10. Hypertension, Vitamin D Deficiency, and Calcium Metabolism / Vin Tangpricha -- 11. Testosterone Deficiency or Male Hypogonadism / Michael Zitzmann -- 12. Insulin Resistance and Hypertension / Helmut O. Steinberg -- 13. Obesity-Associated Hypertension / Gabriel I. Uwaifo -- 14. Central Mineralocorticoid Receptors and Cardiovascular Disease / Elise P. Gomez-Sanchez.
  • 2009 Karger
    volume editors, Marco Cappa, Mohamad Maghnie, Sandro Loche, Gian Franco Bottazzo.
    Inherited and sporadic epimutations at the IGF2-H19 locus in Beckwith-Wiedemann syndrome and Wilms' tumor / Riccio, A. ... [et al.] -- Epigenetic regulation of growth : lessons from Silver-Russell syndrome / Eggermann, T. -- Genetic imprinting : the paradigm of Prader-Willi and Angelman syndromes / Gurrieri, F., Accadia, M. -- Muscle involvement and IGF-1 signaling in genetic disorders : new therapeutic approaches / Barberi, L. ... [et al.] -- Mitochondrial encephalomyopathies and related syndromes : brief review / Bertini, E., D'Amico A. -- Overgrowth syndromes : a classification / Neri, G., Moscarda, M. -- C-type natriuretic peptide and overgrowth / Bocciardi, R., Ravazzolo, R. -- Role of transcription factors in midline central nervous system and pituitary defects / Kelberman, D., Dattani, M.T. -- Developmental abnormalities of the posterior pituitary gland / Di Iorgi, N. ... [et al.] -- Hyperinsulinism in developmental syndromes / Kapoor, R.R., James, C., Hussain, K. -- Developmental syndromes : growth hormone deficiency and treatment / Mazzanti, L. ... [et al.] -- Growth hormone-resistant syndromes : long-term follow-up / Chernausek, S.D. -- Phenotypic aspects of growth hormone- and IGF-I-resistant syndromes / Savage, M.O. ... [et al.] -- Double diabetes : a mixture of type 1 and type 2 diabetes in youth / Pozzilli, P., Guglielmi, C. -- Cryptorchidism as part of the testicular dysgenesis syndrome : the environmental connection / Main, K.M., Skakkebaek, N.E., Toppari, J. -- Disorders of sex development in developmental syndromes / Hiort, O., Gillessen-Kaesbach, G.
  • 2008 ScienceDirect
    edited by Sara E. Walker and Luis J. Jara.
    This book is one of the first to evaluate the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements and focuses on the importance of steroidal hormones in the pathogenesis and therapeutical management of the autoimmune rheumatic diseases. In particular, the chapters analyze the mechanisms of action and the involvement of adrenal steroids (glucocorticoids) in the neuroendocrine immune system, including the effects on elderly. The perturbations of the HPA axis as source of altered steroidal sythesis will be discussed and related to some interesting pathological conditions often complicating the autoimmune rheumatic diseases susch as psychosis or fibromyalgia. Concerning the role of gonadal steroids (sex hormones), several chapters will discuss clinical and epidemiological evidences of their role, as well as their effects as risk factors in autoimmune rheumatic diseases, including a section in Pediatrics. *The premier issue evaluating the role of Steroids in autoimmune rheumatic diseases from the basic mechanisms to the clinical involvements *Documents the latest research and indicate recent and coming new therapeutical-biological approaches to the therapy *The book will present therapeutical perspectives concerning the new glucocorticoids, and the effects of biological drugs on their synthesis.
  • 2010 Springer
    Cord Sturgeon, editor.
    Part. I Thyroid.-- Biology of thyroid oncogenesis / Insoo Suh, Electron Kebebew.-- Evaliation of the thyroid nodule / Dina M. Elaraj.-- Differentiated thyroid cancers of follicular cell origin / Linwah Yip, Sally E. Carty.-- Sporadic medullary thyroid cancer / Adrian Harvey, Janice L. Pasieka.-- Anaplastic thyroid cancer / Alan P.B. Dackiw.-- Part II. Parathyroid.-- Primary hyperparathyroidism / Kaitlyn J. Kelly, Herbert Chen, Rebecca S. Sippel.-- Parathyromatosis and parathyroid cancer / Wen T. Shen.-- Part III. Incidentaloma / Jacob Malem, Insoo Suh, Quan-Yang Duh.-- Pheochromocytoma and paraganglioma / Goswin Y. Meyer-Rochow, Stan B. Sidhu.-- Functional cortical neoplasms / Ali Zarrinpar, Michael W. Yeh.-- Adrenocortical carcinoma / Patsy S.H. Soon, Stan B. Sidhu.-- Part IV. Pnacreatic neuroendocrine tumors.-- Gastrinoma / Anthony J. Chambers, Janice L. Pasieka.-- Insulinoma / Kimberly Vanderveen, Clive Grant.-- Rare neuroendocrine tumors of the pancreas / Shih-Ping Cheng, Gerard M. Doherty.-- Part V. Multiple endocrine neoplasia.-- Menin gene / Hsin-Chieh Jennifer Shen, Steven K. Libutti.-- Multiple endocrine neoplasia type I: clinical manifestations and management / Anathea C. Powell, Steven K. Libutti.-- RET protooncogene / Amber L. Traugott, Jeffrey F. Moley.-- Multiple endocrine neoplasia type 2: clinical manifestations and management / Amber L. Traugott, Jeffrey F. Moely.
    Also available: Print – 2010
  • 2010 Springer
    Ricardo V. Lloyd, editor.
    Methods in cellular and molecular pathology / Paul Komminoth ... [et al.] -- Hypothalamus and neurohypophysis / Kazuhiro Takahashi, Osamu Murakami, and Toraichi Mouri -- Tumors in the adenohypophysis / Fateme Salehi ... [et al.] -- Recent developments in molecular embryogenesis and molecular biology of the pituitary / Robert Y. Osamura and Noboru Egashira -- Recent developments in the molecular biology of pituitary tumors / Ricardo V. Lloyd -- The pineal gland / Katherine M. Lindstrom and M. Beatriz S. Lopes -- The parathyroid / H. Rubén Harach -- Recent developments in the molecular biology of the parathyroid / Vânia Nosé and Ashraf Khan -- Pathology of thyroid gland / Ashraf Khan and Vânia Nosé -- Recent developments in the molecular biology of the thyroid / Yuri E. Nikiforov -- Adrenal cortex / Hironobu Sasano ... [et al.] -- Adrenal medulla and paraganglia / Anne Marie McNicol -- Molecular biology of pheochromocytomas and paragangliomas / Elizabeth E. King and Patricia L.M. Dahia -- Endocrine ovaries / Xavier Matias Guiu -- Endocrine testis / Robert E. Emerson, Liang Cheng, and Thomas M. Ulbright -- Endocrine tumors of the gastrointestinal system / Guido Rindi ... [et al.] -- The endocrine pancreas / Stefano La Rosa ... [et al.] -- Neuroendocrine differentiation patterns in various organs (including lung, breast, skin, and urogenital tract) / Marco Volante ... [et al.] -- Endocrine lung / William D. Travis -- Cutaneous neuroendocrine tumors / Lori A. Erickson -- Neuroendocrine carcinomas of the thymus / Cesar A. Moran and Saul Suster -- Endocrine placenta / Raymond W. Redline -- Fine needle aspiration cytology of endocrine glands / Ema A. Dragoescu and Celeste N. Powers -- Multiple endocrine neoplasia syndrome / Kennichi Kakudo, Yasuhiro Ito, and Masahide Takahashi -- Polyglandular autoimmune diseases / Ricardo V. Lloyd -- Biochemical testing for neuroendocrine tumors / Aaron I. Vinik and Maria P. Silva -- Surgical management of endocrine disorders / Joseph B. Lillegard, Travis J. McKenzie, and Geoffrey B. Thompson -- Medical treatment of neuroendocrine tumors / Timothy J. Hobday -- Radiation treatment of endocrine tumors / Sunil Krishnan, Deepa Suresh, and Robert L. Foote -- Future directions in endocrine pathology / Ricardo V. Lloyd.
  • 2013 AccessMedicine
    Patricia E. Molina.
    This book provides comprehensive coverage of the fundamental concepts of hormone biological action. These concepts provide a solid foundation for understanding the physiologic mechanisms involved in neuroendocrine regulation of organ function. -- Publisher description
  • 2013 ScienceDirect
    2013 ClinicalKey
    [edited by] Michael T. McDermott.
    Continues the tradition of the Secrets Series®, offering fast answers to the most essential clinical endocrinology questions. The Q&A format includes pearls, tips, and memory aids to help you to learn and study efficiently. Provides a concise board review or handy clinical endocrinology resource.
  • 2009 Springer
    Johnathan G.H. Hubbard, William B. Inabnet, and Chung-Yau Lo (eds.).
  • 2014 ClinicalKey
    edited by Tom W.J. Lennard.
    Parathyroid disease / William B. Inabnet III, James A. Lee, and Barnard J.A. Palmer -- The thyroid gland / James C. Lee, Justin S. Gundara, and Stanley B. Sidhu -- The adrenal glands / Sebastian Aspinall -- Familial endocrine disease : genetics, clinical presentation, and management / Paul Brennan, Stephen G. Ball, and T.W.J. Lennard -- Endocrine tumours of the pancreas / Robin M. Cisco and Jeffrey A. Norton -- Gastrointestinal neuroendocrine tumours / Goran Akerstrom, Per Hellman, and Ola Hessman -- Clinical governance, ethics, and medico-legal aspects of endocrine surgery / Peter Angelos and Barnard J. Harrison -- The salivary glands / Paula Bradley, James O'Hara, and Janet Wilson.
  • 2007
    Joy Hinson, Peter Raven, Shern Chew.
    Status: Not Checked OutLane Catalog Record
  • 2010
    Joy Hinson, Peter Raven, Shern Chew ; illustrations by Robert Britton.
    Status: Not Checked OutLane Catalog Record
    Receptors and hormone action -- The hypothalamus and pituitary part I : the hypothalamus and posterior pituitary -- The hypothalamus and pituitary part II : the anterior pituitary -- The adrenal glands part I : the adrenal medulla -- The adrenal glands part II : the adrenal cortex -- The thyroid gland -- Hormonal control of reproduction part I : male reproductive system -- Hormonal control of reproduction part II : female reproductive system -- Hormonal control of reproduction part III : development and fertility -- Insulin and the regulation of plasma glucose -- Hormonal regulation of plasma calcium and calcium metabolism -- Miscellaneous hormones.
  • 2006
    Ben Greenstein, Diana F. Wood.
    Status: Not Checked OutLane Catalog Record
    Chemical transmission -- Mechanisms of hormone action 1. Membrane receptors -- Mechanisms of hormone action 2. Intracellular receptors -- Hypothalamus and pituitary gland -- Gonadotrophin releasing hormone : a peptide hormone -- Principles of feedback control -- Growth 1. Cellular growth factors -- Growth 2. Normal growth -- Growth 3. Growth hormone -- Growth 4. Pathophysiology -- Thyroid 1. Thyroid gland and thyroid hormones -- Thyroid 2. Thyroid hormone secretion and action -- Thyroid 3. Thyroid pathophysiology -- Adrenal gland 1. Adrenal medulla -- Adrenal gland 2. Adrenocortical hormones -- Adrenal gland 3. Adrenocorticotrophic hormone (ACTH) -- Adrenal gland 4. Cortisol and androgens -- Adrenal gland 5. Aldosterone -- Adrenal gland 6. Adrenocortical pathophysiology -- Endocrine autoimmunity -- Sexual differentiation and development 1 -- Sexual differentiation and development 2. Puberty -- Female reproduction 1. Menstrual cycle -- Female reproduction 2. Ovarian steroids -- Female reproduction 3. Pregnancy -- Female reproduction 4. Parturition and lactation -- Female reproduction 5. Pathophysiology -- Female reproduction 6. Contraception -- Male reproduction 1. The testis -- Male reproduction 2. Actions of androgens -- Male reproduction 3. Pathophysiology -- Oxytocin -- Vasopressin -- Renin-angiotensin-aldosterone system -- Endocrine hypertension -- Insulin 1. The pancreas and insulin secretion -- Insulin 2. Insulin action -- Insulin 3. Type I Diabetes mellitus -- Insulin 4. Type 2 Diabetes mellitus -- Glucagon -- Gastrointestinal hormones -- Energy homoeostasis 1. Summary -- Energy homoeostasis 2. Central control -- Obesity 1. Causes of obesity -- Obesity 2. Cardiovascular and respiratory complications -- Obesity 3. Insulin resistance and endocrine complications -- Calcium 1. Parathyroid hormone (PTH) -- Calcium 2. Calcitonin -- Calcium 3. Vitamin D -- Bone remodelling -- Metabolic bone disease 1. Paget's disease -- Metabolic bone disease 2. Primary osteoporosis -- Metabolic bone disease 3. Secondary osteoporosis -- Index.
  • 2013 Karger
    volume editor, Constantine A. Stratakis.
    Multiple endocrine neoplasia type 1 / Agarwal, S.K. -- Multiple endocrine neoplasia type 2 / Lodish, M. -- Von Hippel-Lindau syndrome / Chou, A. ... [et al.] -- Carney complex -- Espiard, S., Bertherat, J. -- Multiple endocrine neoplasia type 4 / Lee, M., Pellegata, N.S. -- Novel hereditary forms of pheochromocytomas and paragangliomas / Dahia, P.L.M. -- Carney triad / Carney, J.A. -- Genetics of pituitary adenomas / Gadelha, M.R. ... [et al.] -- Clinical behavior and genetics of nonsyndromic, familial nonmedullary thyroid cancer / Bauer, A.J. -- Genetic defects associated with familial and sporadic hyperparathyroidism / Hendy, G.N., Cole, D.E.C. -- Endocrine tumors associated with neurofibromatosis type 1, Peutz-Jeghers syndrome, and other familial neoplasia syndromes / Kalkan, E., Waguespack, S.G.
  • v. 25-, 2007- Springer
    Melmed, Shlomo.
  • 2007 Springer
    edited by Andrea C. Gore.
  • v. 1-2, 1952-.
    par P. Sainton, H. Simonnet et L. Brouha.
    Status: Not Checked OutLane Catalog Record
  • v.1-2=, 2016 ClinicalKey
    [edited by] J. Larry Jameson, Leslie J. De Groot, David M. de Kretser, Linda C. Giudice, Ashley B. Grossman, Shlomo Melmed, John T. Potts, Jr., Gordon C. Weir.
  • v. 1-2, 2010.
    senior editors, J. Larry Jameson, Leslie J. De Groot ; section editors, David de Kretser ... [et al.].
    Status: Not Checked OutLane Catalog Record
    V. 1 -- Endocrinology: impact on science and medicine -- Control of hormone gene expression -- Control of hormone secretion -- Insulin and growth factor signaling pathways -- Hormone signaling via G protein-coupled receptors -- Nuclear receptors: structure, function, and coregulators -- Applications of genetics in endocrinology -- Development of the pituitary -- Prolactin -- Adrenocorticotropic hormone -- Endocrine rhythms, the sleep-wake cycle, and biological clocks -- Hypothalamic syndromes -- Hypopituitarism and growth hormone deficiency -- Acromegaly -- Cushing's syndrome -- Clinically nonfunctioning sellar masses -- TSH-producing adenomas -- Disorders of prolactin secretion and prolactinomas -- Pituitary surgery -- Evaluation and management of childhood hypothalamic and pituitary tumors -- Vasopressin, diabetes insipidus, and the syndrome of inappropriate antidiuretic hormone secretion -- The pineal gland and melatonin -- Regulation of growth hormone and action (secretagogues) -- Insulin-like growth factor-1 and its binding proteins -- Somatic growth and maturation -- Growth hormone deficiency in children -- Appetite regulation and thermogenesis -- Obesity: the problem and its management -- Genetic syndromes associated with obesity -- Anorexia nervosa, bulimia nervosa, and other eating disorders -- Development of the endocrine pancreas -- Biosynthesis, processing, and secretion of the islet hormones: insulin, islet amyloid polypeptide (amylin), glucagon, somatostatin, and pancreatic polypeptide -- Insulin secretion -- The mechanisms of insulin action -- Glucagon and the glucagon-like peptides -- Regulation of intermediatory metabolism during fasting and feeding -- Role of the adipocyte in metabolism and endocrine function -- Lipodystrophy syndromes -- Classification and diagnosis of diabetes mellitus -- Type 1 (insulin-dependent) diabetes mellitus: etiology, pathogenesis, prediction, and prevention -- Type 2 diabetes mellitus: etiology, pathogenesis, and natural history -- Lipoprotein metabolism and the treatment of lipid disorders -- Hyperglycemia secondary to nondiabetic conditions and therapies -- The metabolic syndrome -- Treatment of type 1 diabetes mellitus in adults -- Ketoacidosis and hyperosmolar coma -- Hypoglycemia and hypoglycemic syndromes -- Management of type 2 diabetes mellitus -- Management of diabetes mellitus in children -- Pancreatic and islet transplantation -- Diabetes control, long-term complications, and large vessel disease -- Diabetic eye disease -- Diabetes mellitus: neuropathy -- Diabetic nephropathy -- Diabetic foot and vascular complications -- Parathyroid hormone and parathyroid hormone-related peptide in the regulation of calcium homeostasis and bone development -- Calcitonin -- Vitamin D: from photosynthesis, metabolism, and action to clinical applications -- Bone development and remodeling -- Calcium regulation, calcium homeostasis, and genetic disorders of calcium metabolism -- Genetic disorders of phosphate homeostasis -- Primary hyperparathyroidism -- Malignancy-associated hypercalcemia and medical management -- Surgical management of hyperparathyroidism -- Pseudohypoparpathyroidism, Albright's hereditary osteodystrophy, and progressive osseous heteroplasia: disorders caused by inactivating GNAS mutations -- Genetic defects in vitamin D metabolism and action -- Hereditary disorders of the skeleton -- Bone density and imaging of osteoporosis -- Chronic kidney disease mineral and bone disorder -- Disorders of calcification: osteomalacia and rickets -- Paget's disease of bone -- V. 2 -- Anatomy and development of the thyroid -- Thyroid-stimulating hormone: physiology and secretion -- Thyroid regulatory factors -- Thyroid hormone metabolism -- Mechanisms of thyroid hormone action -- Thyroid function testing -- Thyroid imaging -- Autoimmune thyroid disease -- Graves' disease -- Graves' ophthalmopathy -- Autonomously functioning thyroid nodules and other causes of thyrotoxicosis -- Chronic (Hashimoto's) thyroiditis -- Subacute and Riedel's thyroiditis -- Hypothyroidism and myxedema coma -- Nonthyroidal illness syndrome: a form of hypothyroidism -- Multinodular goiter -- Iodine deficiency disorders -- Thyroid neoplasia -- Medullary thyroid carcinoma and multiple endocrine neoplasia type 2 -- Thyroid-stimulating hormone receptor mutations -- Genetic defects in thyroid hormone synthesis and action -- Thyroid hormone binding and variants of transport proteins -- Resistance to thyroid hormone -- Surgery of the thyroid -- The principles, enzymes, and pathways of human steroidogenesis -- Glucocorticoid action: physiology -- Glucocorticoid receptors: their mechanisms of action and glucocorticoid resistance -- Aldosterone: secretion and action -- Glucocorticoid therapy -- Adrenal insufficiency -- Adrenal causes of hypercortisolism -- Defects of adrenal steroidogenesis -- Adrenarche and adrenopause -- Adrenal gland imaging -- Adrenocortical carcinoma -- Primary mineralocorticoid excess syndromes and hypertension -- Mineralocorticoid deficiency -- Pheochromocytoma -- Adrenal surgery -- Hormones of the cardiovascular system -- Hyponatremia and hypernatremia -- Orthostatic hypotension and orthostatic intolerance -- Endocrine aspects of critical care medicine -- Gonadotropin-releasing hormones -- Gonadal peptides: inhibins, activins, follistatin, Müllerian-inhibiting substance (antimüllerian hormone) -- Gonadotropins-regulation of synthesis and secretion -- Genetic basis of gonadal and genital development -- Diagnosis and treatment of disorders of sexual development -- Endocrinology of sexual maturation and puberty -- Precocious puberty -- Delayed puberty -- Hormonal control of breast development -- The endocrinology of sexual behavior and gender identity -- Folliculogenesis, ovulation, and luteogenesis -- Ovarian hormone synthesis -- Estrogen and progesterone action -- Hormonal regulation of the menstrual cycle, mechanisms of ovulation, premenstrual syndromes -- Amenorrhea, anovulation, and dysfunctional uterine bleeding -- Endometriosis -- Female subfertility: evaluation and management -- Hyperandrogenism, hirsutism, and the polycystic ovary syndrome -- Ovulation induction and assisted reproduction -- Contraception -- Menopause -- Functional morphology of the testis -- Androgen physiology, pharmacology, and abuse -- Testicular dysgenesis syndrome, cryptorchidism, hypospadias, and testicular tumors -- Androgen deficiency disorders -- Gynecomastia -- Clinical management of male infertility -- Male contraception -- Endocrinology of the prostate -- The endocrinology of human pregnancy and parturition -- Fetal and neonatal endocrinology -- Diabetes mellitus and pregnancy -- Diagnosis and treatment of thyroid disease during pregnancy -- Hormonal changes and endocrine testing in pregnancy -- Autoimmune polyglandular syndromes -- Multiple endocrine neoplasia type 1 -- Multiple endocrine neoplasia type 2 -- Gastrointestinal hormones and tumor syndromes -- Carcinoid syndrome -- Ectopic hormone syndromes -- Endocrine testing.
  • 2014 Springer
    Francisco Bandeira, Hossein Gharib, Airton Golbert, Luiz Griz, Manuel Faria, editors.
    Endocrinology, and diabetes care in particular, is a dynamic field where clinicians must translate new evidence into clinical practice at a rapid pace. Designed in an engaging, case-based format, Endocrinology and Diabetes: A Problem Oriented Approach offers a wide range of thought-provoking case studies that reflect contemporary, challenging, hands-on clinical care. Further, by providing a list of specific clinical problems, this format offers the reader a more convenient and pointed way to solve precise clinical problems in a timely manner. Developed by a renowned, international group of experts, this comprehensive title covers the most common clinical problems in endocrinology and diabetes and should be of great interest to endocrinologists, diabetologists, internal medicine physicians, family physicians, fellows, and residents.
  • 2015 Springer
    edited by Ramzi Ajjan, Stephen M. Orme.
    Case 1. Difficult-to-treat hyperthyroidism -- Case 2. Hypothyroidism complicated by hypothyroid coma -- Case 3. Hyperthyroidism in pregnancy -- Case 4. Graves' disease associated with a thyroid nodule -- Case 5. A complicated case of thyroid eye disease -- Case 6. Cushing's Syndrome -- Case 7. Prolactinoma presenting with galactorrhoea and secondary amenorrhoea: diagnosis and management -- Case 8. A 25-year-old woman with headache and joint pain -- Case 9. Recent-onset visual field loss and raised prolactin level (non-functioning pituitary tumour ) -- Case 10. Polyuria and polydipsia -- Case 11. Hypertension in the young adult -- Case 12. Weight loss and dizziness: adrenal failure -- Case 13. Diagnosis and management of polycystic ovary syndrome (PCOS) -- Case 14. Salt-wasting crisis in a newborn -- Case 15. Female infertility: diagnosis and management -- Case 16. Diagnosis and management of hypocalcaemia in adults -- Case 17. Hypoglycaemia case study -- Case 18. Spontaneous hypoglycaemia -- Case 19. Thyroid nodule in a child (MEN 2) -- Case 20. What kind of diabetes? -- Case 21. Managing diabetes in pregnancy -- Case 22. Inability to lose weight -- Case 23. Medical problems in obesity -- Case 24. A case of severe hyponatraemia -- Case 25. Medical problems post bariatric surgery -- Index.
  • 2013 Springer
    edited by Naama Constantini, Anthony C. Hackney.
    Understanding the influence and interaction between physical activity and the endocrine system are of paramount importance in dealing with a multitude of health problems. In Endocrinology of Physical Activity and Sport, renowned physicians and researchers provide a comprehensive and expanded update on the scientific, clinical and practical components of endocrinology as related to sport and exercise. The authors thoroughly review what is known about how such activity affects the endocrine system and how in turn these hormonal responses affect many other organs and systems of the body. In addition, aspects of endocrinology in non-glandular tissue which have endocrine actions are addressed; for example, adipocytes and the release of leptin and related adipocytokines. Further, a wide range of clinically related topics such as athletic amenorrhea, osteopenia, sarcopenia, and hypogonadism are included. This new edition critically integrates what is known about the complex interaction of the endocrine system in the sports context and will again prove immensely valuable to all physicians and clinical investigators treating those active in sports today.
  • v. 1-3, 2006.
    senior editors, Leslie J. DeGroot, J. Larry Jameson ; section editors, David de Kretser ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2009 Karger
    volume editors, W.H.B. Wallace, C.J.H. Kelnar.
    Hypopituitarism following radiotherapy revisited / Darzy, K.H., Shalet, S.M. -- Alterations in pubertal timing following therapy for childhood malignancies / Armstrong, G.T., Chow, E.J., Sklar, C.A. -- Obesity during and after treatment for childhood cancer / Reilly, J.J. -- Metabolic disorders / Gregory, J.W. -- Bone and bone turnover / Crofton, P.M. -- Male fertility and strategies for fertility preservation following childhood cancer treatment / Mitchell, R.T. ... [et al.] -- Fertility in female childhood cancer survivors / De Bruin, M.L. ... [et al.] -- Long-term follow-up of survivors of childhood cancer / Edgar, A.B. ... [et al.].
  • 2015 Springer
    Bettina Basrani, editor.
    This book reviews the available information on bacterial disinfection in endodontics, with emphasis on the chemical treatment of root canals based on current understanding of the process of irrigation. It describes recent advances in knowledge of the chemistry associated with irrigants and delivery systems, which is of vital importance given that chemical intervention is now considered one of the most important measures in eliminating planktonic microbes and biofilms from the infected tooth. Recommendations are made regarding concentrations, exposure times, and optimal sequences. Possible complications related to the use of the different solutions are highlighted, with guidance on response. In addition, clinical protocols are suggested on the basis of both clinical experience and the results of past and ongoing research. Throughout, a practical, clinically oriented approach is adopted that will assist the practitioner in ensuring successful endodontic treatment.
  • 2014 Springer
    Paul A. Rosenberg.
    Endodontic pain is a complex symptom that often drives a patient to a dentist in search of relief. In these circumstances, the patient is likely to pose a range of questions: Can you relieve my pain? Will the treatment be painful? How will I feel later? The answers to such questions often form the basis of the patient's assessment of the dentist. The combination of pain and a negative dental experience has physical and psychological sequelae for the patient that may last long after treatment. This book is a concise, well-structured guide to the assessment and treatment of patients who present with endodontic pain, in which step-by-step descriptions are complemented by informative images and flow charts. The advantages, disadvantages, and significance of specific diagnostic and treatment procedures are clearly described, as is a pharmacotherapeutic approach to the prevention and treatment of pain. In addition, the causes and biological basis of endodontic pain are explained and guidance is provided on further strategies for pain prevention. The crisp narrative, efficient design, and visual detail are notable features of this book that will make it an ideal chairside resource for the clinician and a dependable reference for the student.
  • 2014 ScienceDirect
    edited by Kishor Gulabivala, BDS, MSc, FDS RCS (Edin), PhD, FHEA, Yuan-Ling Ng, BDS, MSc, MRD RCS (Eng), PhD, FHEA.
    Tooth development, morphology and physiology / Kishor Gulabivala, Yuan-Ling Ng -- Biological and clinical rationale for vital pulp therapy / Kishor Gulabivala, Yuan-Ling Ng -- Biological and clinical rationale for root canal treatment / Kishor Gulabivala, Yuan-Ling Ng -- Diagnosis of endodontic problems / Kishor Gulabivala, Yuan-Ling Ng -- Treatment planning / Kishor Gulabivala, Yuan-Ling Ng -- Pre-endodontic management / Kishor Gulabivala, Yuan-Ling Ng -- Delivery of endodontic treatment -- Vital pulp therapy / Kishor Gulabivala, Yuan-Ling Ng -- Non-surgical root canal treatment / Kishor Gulabivala, Yuan-Ling Ng -- Management of root canal treatment failure / Yuan-Ling Ng, Kishor Gulabivala -- Management of emergencies and traumatic injuries / Kishor Gulabivala, Yuan-Ling Ng -- Management of root resorption / Yuan-Ling Ng, Kishor Gulabivala -- The perio-endo interface / Kishor Gulabivala, Ulpee Darbar, Yuan-Ling Ng -- The ortho-endo interface / Kishor Gulabivala, Farhad Naini -- The restorative-endo interface / Kishor Gulabivala, Yuan-Ling Ng -- The medical-endo interface / Alexander Mustard, Kishor Gulabivala -- The orofacial pain-endo interface / Rachel Leeson, Kishor Gulabivala, Yuan-Ling Ng -- The oral medicine/oral surgery-endo interface / Rachel Leeson, Kishor Gulabivala.
  • 2015 ClinicalKey
    Mahmoud Torabinejad, DMD, MSD, PhD, Professor and Program Director, Department of Endodontics, School of Dentistry, Loma Linda University, Loma Linda, California, Richard E. Walton, DMD, MS, Professor Emeritus, Department of Endodontics, The University of Iowa, College of Dentistry, Iowa City, Iowa, Ashraf F. Fouad, BDS, DDS, MS, Department of Endodontics, Prosthodontics and Operative Dentistry, School of Dentistry, University of Maryland, Baltimore, Maryland.
    The biology of dental pulp and periradicular tissues / Graham Rex Holland, Mahmoud Torabinejad -- Protecting the pulp and promoting tooth maturation / Ashraf F. Fouad, Anthony J. Smith -- Endodontic microbiology / José F. Siqueira, Jr., Ashraf F. Fouad -- Pulp and periapical pathosis / Mahmoud Torabinejad, Shahrokh Shabahang -- Diagnosis, treatment planning and systemic considerations / Richard E. Walton, Ashraf F. Fouad -- Interaction between the general dentist and the endodontist / Ashraf F. Fouad, Mahmoud Torabinejad -- Endodontic-periodontic interelationship / Mahmoud Torabinejad, Ilan Rotstein -- Longitudinal tooth fractures / Eric M. Rivera, Richard E. Walton -- Local anesthesia / Al Reader, John M. Nusstein, Richard E. Walton -- Endodontic emergencies and therapeutics / Paul D. Eleazer, Paul A. Rosenberg -- Management of traumatic dental injuries / Nestor Cohenca -- Endodontic radiography / Richard E. Walton, Ashraf F. Fouad -- Endodontic instruments / Van T. Himel, Kent A. Sabey -- Internal anatomy / Richard E. Walton, Eric J. Herbranson -- Isolation, endodontic access, and length determination / William T. Johnson, Anne E. Williamson -- Cleaning and shaping / Ove A. Peters, W. Craig Noblett -- Preparation for restoration / Charles J. Goodacre, Harold H. Messer -- Obturation / James C. Kulild, Bekir Karabucak -- Procedural accidents / Mahmoud Torabinejad, James D. Johnson -- Retreatment / George Bogen, Robert Handysides -- Endodontic surgery / Mahmoud Torabinejad, Bradford R. Johnson -- Evaluation of endodontic outcomes / Mahmoud Torabinejad, Shane N. White -- Single implant / Mohammad A. Sabeti, Mahmoud Torabinejad -- Bleaching discolored teeth / Ilan Rotstein, Richard E. Walton -- Geriatric endodontics / Richard E. Walton -- Appendix. Pulpal anatomy and access preparations / Lisa R. Wilcox.
  • 2015 Springer
    Sarah J. Goodlin, Michael W. Rich, editors.
    Cardiovascular (CV) disease is the leading cause of death worldwide. While death rates from many acute CV illnesses have declined in developing countries, a substantial proportion of individuals with CV disease ultimately die from CV causes. As the population ages, the global burden of CV disease will continue to rise. Until recently, the focus of clinicians has been on saving lives and deferring death. Over the past decade there has been growing recognition of the importance of palliative care and end of life care in CV disease. While palliative and supportive care should be provided throughout the course of serious and life-shortening illnesses, this book focuses on issues that clinicians encounter in end-of-life care. This book provides guidance to clinicians working across the breadth of care settings, in chronic progressive disease as well as sudden arrhythmic death andwith advanced technologies. End-of-Life Care in Cardiovascular Disease is designed to assist clinicians, nurses, and other healthcare providers in addressing end of life care for patients with CV disease in a variety of common clinical scenarios. Each chapter is written by expert clinicians and researchers, and concisely reviews current knowledge and recommendations for providing patient- and family-centered end-of-life care.
  • 2008 Springer
    David W. Crippen, editor.
    Introduction -- Chapter 1. Multinational Perspectives on End-of-Life Issues in the Intensive Care Unit -- The United States -- Canada -- New Zealand -- United Kingdom -- Communicating to family: the Israeli perspective -- Maria and the good death: the Latin American view -- The Greek perspective -- The South African perspective -- A perspective from India -- Japan -- Chapter 2. Critical Illness and End-of-Life Issues: A Global View -- An evaluation of international medical ethics at the end of life -- Communication in the Intensive Care Unit -- End-of Life issues in the critically ill: a global perspective -- Chapter 3. Death in a Lonely Place: Pathophysiology of the Dying Patient -- Chapter 4. The History of the Definition(s) of Death: From the 18th Century to the 20th Century -- Chapter 5. What It Feels Like to Live and Die on Prolonged Life Support -- Chapter 6. Who's in Charge in the Intensive Care Unit? -- Chapter 7. Dealing with Difficult Surrogates -- Erring on the side of autonomy -- Erring on the side of reason -- Healthcare providers' contribution to the problem of futility -- Chapter 8. Emotions in the Intensive Care Unit -- Chapter 9. The Role of Ethics Committees in End-of-Life Care -- Chapter 10. Medical Liability Issues in Dealing with Critical Care Patients in the End-of-Life Situation -- Chapter 11. End-of-Life Issues and United States Politics -- Chapter 12. Comments from Ancillary Healthcare Providers -- My experiences with end-of-life as a bedside-nurse -- A Chaplain's perspective -- Pharmacotherapy considerations during end-of-life care of critically ill adults -- Chapter 13. The Intensive Care Unit of the Future -- Afterword.
  • 2013
    Joanna De Souza and Annie Pettifer.
    Status: Not Checked OutLane Catalog Record
  • 2015 Springer
    Friedrich Koch-Nolte, editor.
    Part I. Evolution and detection of endogenous ADP-ribosylation. The natural history of ADP-ribosyltransferases and the ADP-ribosylation system / L. Aravind, Dapeng Zhang, Robson F. de Souza, Swadha Anand and Lakshminarayan M. Iyer -- Identification and analysis of ADP-ribosylated proteins / Friedrich Haag and Friedrich Buck -- Part II. ADP-ribosylation by ARTCs (R-S-E ARTs). Photorhabdus luminescens Toxins TccC3 and TccC5: insecticidal ADP-ribosyltransferases that modify threonine and glutamine / Klaus Aktories, Gudula Schmidt and Alexander E. Lang -- Reaction mechanism of mno-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein / Hideaki Tsuge and Toshiharu Tsurumura -- Regulation of nitrogenase by reversible mono-ADP-ribosylation / Vivian R. Moure, Flavia F. Costa, Leonardo M. Cruz, Fabio O. Pedrosa, Emanuel M. Souza, Xiao-Dan Li, Fritz Winkler and Luciano F. Huergo -- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells / Björn Rissiek, Friedrich Haag, Olivier Boyer, Friedrich Koch-Nolte and Sahil Adriouch -- Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish / Tsuyoshi Nakano, Azusa Takahashi-Nakaguchi, Masafumi Yamamoto and Masahiko Watanabe -- Part III. ADP-ribosylation by ARTDs (H-Y-E ARTs). Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family / Ana Filipa Pinto and Herwig Schüler -- Function and regulation of the mono-ADP-ribosyltransferase ARTD10 / Max Kaufmann, Karla L.H. Feijs and Bernhard Lüscher -- Regulation of nucleocytoplasmic transport by ADP-tibosylation: the emerging role of Karyopherin-[Beta]1 mono-ADP-ribosylation by ARTD15 / Maria Di Girolamo -- Index.
  • 2008 Karger
    Matías Jiménez-Ayala, Beatriz Jiménez-Ayala Portillo ; including contributions by Enrique Iglesias Goy, Mar Rios Vallejo.
    Current status of the prevention and early diagnosis of endometrial adenocarcinoma -- The value of endometrial cytology -- Techniques of endometrial cytology -- Techniques of endometrial histopathology -- New techniques for the diagnosis of endometrial pathology -- Cytology of the normal endometrium - cycling and postmenopausal -- Benign endometrial lesions -- Cytopathology of endometrial hyperplasias -- Cytopathology of endometrial adenocarcinoma -- Cytopathology of the non-epithelial malignant tumors of the uterine corpus.
    Also available: Print – 2008
  • 2009 Springer
    John A. Maksem, Stanley J. Robboy, John W. Bishop, Isabelle Meiers.
  • 2015 Springer
    Sajal Gupta, Avi Harlev, Ashok Agarwal.
    Introduction -- Predisposing and protective factors of endometriosis -- Theories on endometriosis -- Oxidative stress and endometriosis -- Role of iron in the pathogenesis of endometriosis -- Role of environmental pollutants in endometriosis -- Endometriosis and ovarian cancer -- Endometriosis: impact on quality of life -- Diagnosis of endometriosis -- Management of endometriosis -- Concluding remarks.
  • 2014 Springer
    Tasuku Harada, editor.
    Endometriosis is one of the most common gynecological diseases, causingpelvic pain, infertility, and cancer. The condition reduces the quality of life for the estimated 10% of menstruating women who are affected by it. This book provides a clear insight intothe pathogenesis and pathophysiology of endometriosis-essentialinformation forcliniciansintending to successfully treat the condition. The first part covers a range of topics including stem cells, NK cells, macrophages, inflammation, cytokines, epigenetics, prostaglandin, sex steroids, aromatase, apoptosis, nerve fibers, and malignant transformation to aid in understanding the pathogenesis and pathophysiology of the disease. The second part provides useful tools for therapy, specifically, notable recent techniques in prevention, imaging, biomarkers, medical treatments, surgical treatments, prevention of recurrence, and infertility treatments. Each chapter was written by an expert in the field, with nearly 40 researchers and clinicians contributing to the work. This book will be highly useful to clinicians as well as to research scientists who are interested in this enigmatic disease.
  • 2012 Springer
    edited by Patrizia Agostinis, Afshin Samali.
    The Endoplasmic Reticulum (ER) is an organelle with extraordinary signaling and homeostatic functions. It is the organelle responsible for protein folding, maturation, quality control and trafficking of proteins destined for the plasma membrane or for secretion into the extracellular environment. Failure, overloading or malfunctioning of any of the signaling or quality control mechanisms occurring in the ER may provoke a stress condition known as âER stressâ. Accumulating evidence indicates that ER stress may dramatically perturb interactions between the cell and its environment, and contribute to the development of human diseases, ranging from metabolic diseases and cancer to neurodegenerative diseases, or impact therapeutic outcome. This book primarily focuses on the pathophysiology of ER stress. It introduces the molecular bases of ER stress, the emerging relevance of the ER-mitochondria cross-talk, the signaling pathways engaged and cellular responses to ER stress, including the adaptive Unfolded Protein Response (UPR), autophagy as well as cell death. Next the book addresses the role of ER stress in physiology and in the etiology of relevant pathological conditions, like carcinogenesis and inflammation, neurodegeneration and metabolic disease. The last chapter describes how ER stress pathways can be targeted for therapeutic benefit. Altogether, this book will provide the reader with an exhaustive view of ER stress biology and the latest insights in the role of ER stress in relevant human diseases.
  • 2006 Springer
    Wolfgang Seeger ; in collaboration with J.P. Warnke, St. Rosahl, and A. Weyerbrock.
  • 2010 Springer
    Wolfgang Seeger ; in collaboration with Jan Kaminsky and Astrid Weyerbrock.
    Survey -- Cavum nasi and fossa pterygopalatina -- Sinus sphenoidalis and fossa pterygopalatina -- Tuba auditiva (eustachii) -- Pyramis (petrous bone, pars petrosa plus pars tympanica) -- Clivus area and pars condylaris -- Special surgical aspects examples.
  • 2008 Springer
    Wolfgang Seeger ; in collaboration with Jan Kaminsky and Astrid Weyerbrock.
  • 2012 Karger
    volume editors, Amin B. Kassam, Paul A. Gardner.
  • 2016 Springer
    Jeffrey Cheng, John P. Bent, editors.
    External and Middle Ear -- Nasal Cavity and Nasopharynx -- Oral Cavity and Oropharynx -- Airway and Aerodigestive Tract.
  • 2016 Springer
    Tsuneo Oyama, editor.
    This book covers pre-operative diagnosis and new techniques for dissecting early-stage gastric cancer. With abundant color figures and extensive explanations, it covers actual practice scenarios, including difficult-to-treat cases.
  • 2015 Thieme-Connect
    [edited by] Livio Presutti, Daniele Marchioni.
    "Increasingly used as an adjunctive tool in the diagnosis and management of ear disease, middle ear endoscopy has the potential to decrease patient morbidity, prevent disease recurrence, and reduce costs. Its capacity to uncover hidden anatomy within the small dimensions of the ear has made it essential for functional surgery, allowing surgeons to preserve key anatomic structures such as the cochlea and facial nerve. Now for the first time, the physicians who pioneered this groundbreaking minimally invasive technique review its indications, advantages, disadvantages, and surgical approaches. Written by the foremost leaders in the field, all members of the International Working Group on Endoscopic Ear Surgery. Features nearly 1,000 intraoperative endoscopic images filmed with high-definition cameras, plus outstanding line drawings that aid in understanding all concepts. Comprehensively covers the field, including chapters on endoscopic and combined endoscopic-microscopic management of cholesteatoma, surgical restoration of middle ear ventilation, myringoplasty, Meniere disease, tympanoplasty and stapes surgery, revision surgery, and much more. Demonstrates state-of-the-art endoscopic procedures in 19 instructive videos. From the unique anatomy and pathophysiology of the middle ear through diagnosis, surgical indications, procedures, and instrumentation, this book is indispensable for all otolaryngologists and neurotologists. It offers a full picture of the field today, as well as exploring the future possibilities of ear endoscopes alone or in combination with operative microscopes for the most effective treatment of middle ear pathologies"--Provided by publisher.
  • 2007 Springer
    J.-U. Stolzenburg, M.T. Gettman, E.N. Liatsikos (eds.).
  • 2014 Springer
    Giuseppe Galloro, editor.
    Owing to the alterations in visceral anatomy, many endoscopists, and especially trainees, experience difficulties when performing endoscopic surveys or procedures in patients who have previously undergone surgery to the digestive tract. In this richly illustrated book, an expert in the field provides a detailed overview of endoscopic follow-up of gastrointestinal (esophageal, gastric, and colorectal) anastomosis. Both normal appearances and pathological conditions involving complications are fully covered. The methodology, timing, protocols, and role of diagnostic endoscopy are first discussed. Endoscopic treatments for the resolution of different clinical problems related to recurrences, stenoses, dehiscences, and fistulas are then evaluated step by step with the aid of high-quality images. Regardless of level of experience, endoscopists and gastroenterologists will find Endoscopic Follow-up of Digestive Anastomosis to be an invaluable source of information and aid to treatment in this important area, which too often receives insufficiently detailed attention.
  • 2016 Springer
    Vani J.A. Konda, Irving Waxman, editors.
  • 2008
    edited by Massimo Conio ... [et al.].
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    edited by Douglas O. Faigel, Michael L. Kochman.
    Barrett's esophagus : screening, diagnosis, and management / Glenn M. Eisen -- Endoscopic screening for squamous cell carcinoma of the esophagus / Brian C. Jacobson -- Image enhancement endoscopy / Stephan M. Wildi and Michael B. Wallace -- Staging of esophageal cancer / Jason Vollweiler and Gregory Zuccaro, Jr. -- Endoscopic therapy for early esophageal cancer and premalignant lesions in Barrett's esophagus / Granapathy A. Prasad and Kenneth K. Wang -- Endoscopic therapy for advanced esophageal cancer / Sanjay Jagannath and Marcia I. Canto -- Radiological imaging of the upper gastrointestinal tract / Marc S. Levine -- Esophageal cancer therapy : surgery, radiation, and chemotherapy / John M. Holland and Christopher A. Canning -- Premalignant lesions of the stomach / Omid A. Shaye and Andrew Ippoliti -- Gastric polyps / George A. Makar and Gregory G. Ginsberg -- Endoscopic ultrasound for staging gastric cancer / Gregory Olds and Amitabh Chak -- Endoscopic treatment for gastric cancer / Takuji Gotoda and Roy M. Soetikno -- Diagnosis and management of gastrointestinal lymphoma / John G. Kuldau, Peter R. Holman, and Thomas J. Savides -- Gastrointestinal stromal tumors / Raquel E. Davila -- Carcinoid tumors / Wilscott E. Naugler and Gordon C. Hunt -- Medical and surgical therapy for gastric cancer / Diane Hershock -- Colorectal cancer screening / Jason A. Dominitz and William M. Grady -- Polyposis and familial cancer syndromes / Fernando S. Velayos, Madhulika G. Varma, and Jonathan P. Terdiman -- Endoscopic colon surveillance : post-polypectomy, post-colorectal cancer resection, and inflammatory bowel disease / Douglas B. Nelson and Mandeep S. Sawhney -- Endoscopic ultrasound for staging rectal and anal cancer / Deepak V. Gopal -- Endoscopic therapy of colorectal carcinoma / Vaman Jakribettuu and Yang K. Chen -- Radiological imaging of the lower gastrointestinal tract / Steven E. Rubesin -- Current status of colorectal cancer therapy / John Strother ... [et al.] -- Cystic neoplasms of the pancreas / William R. Brugge -- Diagnosis and evaluation of pancreatic ductal adenocarcinoma / Kenneth H. Yu and Nuzhat A. Ahmad -- Adenocarcinoma of the pancreas : endoscopic palliation / Georgios I. Papachristou, Kevin McGrath, and Adam Slivka -- Pancreatic neuroendocrine tumors / Erik-Jan Wamsteker and James M. Scheiman -- Endoscopic diagnosis and management of cholangiocarcinoma / Vanessa M. Shami and Irving Waxman -- Ampullary neoplasia / Ian D. Norton -- Magnetic resonance imaging of neoplasms of the pancreatobiliary system / Evan S. Siegelman and Wendy C. Hsu -- Medical and surgical therapy of pancreatic cancer / Weijing Sun, Jon Morris, and Jeffrey Drebin -- Endoscopic ultrasound for thoracic disease / Timothy Woodward, Massimo Raimondo, and Michael B. Wallace.
  • 2012 Thieme eNeurosurgery
    [edited by] Theodore H. Schwartz, Vijay K. Anand.
    1. History of Pituitary Surgery -- 2. Anatomy of the Pituitary Gland and Parasellar Region -- 3. Endoscopic Equipment -- 4. Preoperative Endocrine Evaluation -- 5. Radiographic Evaluation of Pituitary Tumors -- 6. Indications for Surgery on Pituitary Tumors: An Endocrinologist's Perspective -- 7. Indications for Surgery on Pituitary Tumors: A Neurosurgeon's Perspective -- 8. Histology of Pituitary Tumors -- 9. Prolactinomas and Apoplexy -- 10. Acromegaly -- 11. Cushing's Disease -- 12. Thyroid-Stimulating Hormone Tumors -- 13. Clinical Management of Nonfunctioning Pituitary Adenomas -- 14. Neuro-Ophthalmologic Considerations -- 15. Endoscopic Transsphenoidal Approach to the Sella -- 16. Clinical Pearls in Endoscopic Pituitary Surgery: A Neurosurgeon's Perspective -- 17. Clinical Pearls in Endoscopic Pituitary Surgery: An Otolaryngologist's Perspective -- 18. Virtual Endoscopy in Endoscopic Pituitary Surgery -- 19. 3D Stereoendoscopic Pituitary Surgery -- 20. Endoscope-Assisted Transsphenoidal Surgery -- 21. Endoscopic Pituitary Surgery in the Cavernous Sinus -- 22. Microscopic versus Endoscopic Transsphenoidal Pituitary Surgery -- 23. Microscopic and Endoscopic Transsphenoidal Pituitary Surgery: A Reasoned and Balanced Dialectic -- 24. Extended Endonasal, Endoscopic Transsphenoidal Approach versus Craniotomy for Giant Pituitary Macroadenomas -- 25. Stereotactic Radiosurgery and Fractionated Radiation for Pituitary Tumors -- 26. Atypical Adenoma, Pituitary Carcinoma, and the Role of Chemotherapy in the Management of Refractory Pituitary Adenoma -- 27. The Utility of Intraoperative MRI in Pituitary Surgery -- 28. Limited Utility of Intraoperative MRI in Endoscopic Pituitary Surgery -- 29. The Role of Stereotactic Navigation in Endoscopic Pituitary Surgery -- 30. Anesthesia Considerations -- 31. Managing Postoperative Sinusitis -- 32. Managing Carotid Injury During Transsphenoidal Surgery -- 33. Managing Postoperative CSF Leak -- 34. Postoperative and Neurocritical Care Management of Patients after Endonasal Endoscopic Transsphenoidal Pituitary Surgery -- Index.
  • 2001 NLM
    prepared by Karen Patrias, Peggie S. Tillman, Frank A. Hamilton.
  • 2008 Springer
    by Hrayr K. Shahinian.
  • 2011 Thieme eNeurosurgery
    [edited by] Daniel H. Kim, Gun Choi, Sang-Ho Lee.
    "As the understanding of human physiology has become more complete, the importance of preserving normal tissues has become increasingly clear in the field of surgery. This understanding gave birth to the concept of minimally invasive surgery that has conquered almost all surgical fields, including spine surgery. With recent advances and experience, minimally invasive spinal surgery (MISS) is gradually replacing conventional spine surgical procedures. The primary goal of MISS is to achieve outcomes comparable to those of open surgery while minimizing normal tissue damage and reducing recovery times. Advances in optics, radionavigation, and laser technology made MISS more accessible to surgeons and truly less invasive for the patient. Minimally invasive surgical techniques have touched the entire spinal column, from the cervical to the lumbosacral spine. The MISS spectrum ranges from simple disk surgeries to the most complicated spine surgeries, such as deformity correction. Of all MISS procedures, percutaneous endoscopic disk surgery has attracted the most attention from the global spine surgery community and has enjoyed phenomenal advances in sophistication in the past decade. The remainder of the chapter presents a historical account of percutaneous disk surgeries for the lumbar and cervical spine. "--Provided by publisher.
  • 2015 Springer
    Norio Fukami, editor.
    History of ESD -- Indications of ESD in the Upper Gastrointestinal Tract -- Indication for Colorectal ESD -- Role of EUS on Preoperative Staging of Gastric Cancer for ESD -- Advanced Endoscopic Imaging in the Upper Gastrointestinal Tract -- Advanced Endoscopic Imaging in the Lower Gastrointestinal Tract -- Injection Material for ESD -- Eastern Perspective -- Submucosal Fluid Cushion Injection Fluid -- Western Perspective -- Electrocautery -- Endoscopic Submucosal Dissection for Superficial Esophageal Cancer -- ESD Technique: Stomach -- Endoscopic Submucosal Dissection Technique: Colorectum -- How to Conquer Difficult ESD: Duodenum, Fibrosis, and More -- Prevention of Stricture Formation after Esophageal Endoscopic Submucosal Dissection -- Regenerative Medicine for Stricture Management: What does the Future Hold? -- Prevention, Identification, and Treatment of Hemorrhage -- Management of Gastrointestinal EMR & ESD perforation: From Lab to Practice -- Identification, Treatment, and Prevention of Complications: Perforation in the Upper Gastrointestinal Tract -- Prevention, Identification, and Treatment of Perforation in the Lower Gastrointestinal Tract -- Post-resection surveillance -- POEM -- ESD Expansion: NOTES ? Eastern perspective -- ESD Expansion: NOTES ? The Western Perspective -- ESD Training in the East -- ESD training in Western Countries.
  • 2008 Springer
    Klaas (N) M.A. Bax ... [et al.], editors.
  • 2016 Springer
    Livio Presutti, Francesco Mattioli, editors.
    This manual covers all aspects of endoscopic surgery of the lacrimal drainage system. Step-by-step descriptions are provided of endoscopic dacrocystorhinostomy (DCR) and its use in revision surgery, accompanied by numerous helpful photographs and anatomical drawings. In addition, clear flow charts are included to aid in diagnostic and surgical decision making and identify surgical indications. Essential information is provided on anatomy, physiology, and pathology, and an individual chapter is devoted to imaging of the lacrimal drainage system. Further topics include lacrimal probes and stents, potential complications of surgery, and endoscopic DCR in the pediatric age group. This book will assist the practitioner in negotiating the steep learning curve involved in gaining the skills needed to perform endoscopic surgery of the lacrimal drainage system, which offers significant advantages in terms of avoidance of external incisions and maintenance of the lacrimal pump.
  • 2005 Springer
    edited by Attilio Maria Farinon ; assistant editor, Francesco Rulli.
    Also available: Print – 2005
  • 2009 Springer
    edited by Richard E. Sampliner.
    New technologies for imaging of Barrett's esophagus -- Argon plasma coagulation in Barrett's esophagus: the most widely available technique -- Radiofrequency ablation for eradication of Barrett's esophagus: a description of the endoscopic technique, its clinical results, and future prospects -- Decision making in ablation: disease, patients, and institutional factors -- Multipolar electrocoagulation (MPEC): an early, widely available technique -- Endoscopic mucosal resection in Barrett's esophagus: endoscopic surgery -- Combination: multimodal therapy -- Photodynamic therapy (PDT): the best-validated technique -- Cyroablation of Barrett's esophagus -- Cost-effectiveness of endoscopic therapy for Barrett's esophagus.
  • 2010 Springer
    edited by Vanessa M. Shami and Michel Kahaleh.
    Endosonographic instrumentation -- Probe ultrasonography -- Radial endoscopic ultrasound -- Linear endoscopic ultrasound -- The cytopathology of endoscopic ultrasound-guided fine needle aspiration -- Pitfalls in endoscopic ultrasound -- The role of EUS in esophageal cancer -- Role of EUS in mediastinal nodes, masses, cysts, and lung cancer -- The role of endoscopic ultrasound in gastric cancer -- The role of EUS in subepithelial lesions -- Endoscopic ultrasound of ampullary and duodenal lesions -- The role of EUS in pancreatic cancer -- The role of EUS in cystic lesions of the pancreas -- The role of EUS in the biliary system -- The role of EUS in rectal cancer and fecal incontinence -- Interventional endoscopic ultrasound-guided cholangiopancreatography -- Endoscopic ultrasound-guided drainage of pancreatic fluid collections -- Endoscopic ultrasound-guided celiac plexus block and celiac plexus neurolysis -- Fine needle injection therapy -- Contrast-enhanced endoscopic ultrasound -- Endosurgical applications of EUS -- The future of EUS.
  • 2006
    [edited by] Christoph Frank Dietrich ; with contributions by H. Allgayer ... [et al.] ; foreword by Wolfgang F. Caspary.
    Status: Not Checked OutLane Catalog Record
    Basics of radial endoscopic ultrasound -- Longitudinal EUS anatomy -- EUS meets VOXEL-MAN: a computer-based training system for longitudinal EUS -- Miniprobes -- Intraductal ultrasound -- Radial EUS, linear EUS, or ultrasound miniprobe: which if the most suitable device? -- Ultrasound contrast agents and contrast-enhanced ultrasonography.
  • 2015 Springer
    Richard Kozarek, Michael Chiorean, Michael Wallace, editors.
    The Evaluation, Diagnosis, and Treatment of Inflammatory Bowel Diseases over the Past 100 Years: A Brief Review -- Ultrasound -- Fluoroscopic Techniques for the Interrogation of IBD Patients -- CT Enterography in Crohn's Disease -- Magnetic Resonance Enterography (MRE) -- Role of Endoscopy in Diagnosis of Crohn's Disease and Chronic Ulcerative Colitis -- Capsule Endoscopy in the Evaluation of Inflammatory Bowel Disease -- Balloon-assisted Enteroscopy: Techniques, Diagnostic and Therapeutic Yield and Application in Small Bowel Crohn?s Disease -- Spiral Enteroscopy: Technique, Diagnostic and Therapeutic Yield and Application in Small Bowel Crohn?s Disease -- Diseases That Can Mimic IBD -- Histopathologic Diagnosis of Inflammatory Bowel Disease -- Role of Mucosal Healing -- Role of Endoscopy to Define Postoperative Recurrence in IBD -- The Use of Endoscopy to Follow the Clinical Course of Crohn?s Disease -- Endoscopy in Crohn's Disease of the Pouch -- Endoscopic Surveillance for Neoplasia in IBD: Random Biopsy -- The Near Future of Endoscopic Screening in IBD -- Surveillance for Neoplasia in the Patient with an Ileal Pouch -- Pathology DALM -- Endoscopic Approach to Resection of Polypoid and Non-Polypoid Dysplasia in IBD -- Endoscopic Treatment of Complications of Inflammatory Bowel Diseases -- Diagnosis and Treatment: ERCP in PSC -- Future of Endoscopy and IBD.
  • 2015 Springer
    Richard Kozarek, Jonathan A. Leighton, editors.
    This volume reviews the history of endoscopy to diagnose small bowel disorders, places other diagnostic modalities into perspective, and defines the role of capsule endoscopy and per overtube assisted and retrograde enteroscopy in disorders as disparate as gluten sensitive enteropathy, small bowel neoplasms, and inflammatory bowel disease. The book further details the nonoperative approach to NSAID strictures, foreign body retrieval (to include impacted capsule endoscopes), and the diagnosis and treatment of chronically bleeding angiodysplastic lesions. The text is also richly illustrated with over 150 images and includes online video segments. Written by experts in the field, Endoscopy in Small Bowel Disorders is a valuable resource for medical and surgical residents, gastroenterologists in training and practice, therapeutic endoscopists, and general and colorectal surgeons.
  • 2014 Springer
    Toshiyuki Matsui, Takayuki Matsumoto, Kunihiko Aoyagi, editors.
    The purpose of this book is to improve diagnostic yields of capsule endoscopy and double-balloon endoscopy, because those procedures can depict nonspecific findings that may not lead to a proper diagnosis. Another reason for the publication was recognition of the difficulty in distinguishing enteroscopic findings of ulcerative colitis from those of Crohn's disease. From a practical point of view, it is important to observe endoscopic pictures first, then to compare the images of other modalities, and finally to compare macroscopic pictures of resected specimens. For that reason, a large number of well-depicted examples of small intestinal lesions were assembled to clarify differences among small intestinal lesions that appear to exhibit similar findings and morphologies. Comparisons with radiographic findings comprise another important element in diagnosis. There are limitations in endoscopic observations of gross lesions of the small intestine, with its many convolutions. In Japan, many institutions still practice double-contrast imaging, which provides beautiful results. Because a single disorder may exhibit variations, this volume includes multiple depictions of the same disorders. Also included are lesions in active and inactive phases, as both appearances are highly likely to be encountered simultaneously in clinical practice. The number of illustrated findings therefore has been limited to strictly selected cases.
  • pt. A-B, 2014 ScienceDirect
    pt. B ScienceDirect
    volume editor, P. Michael Conn.
  • 2006
    edited by Robert H. Hawes, Paul Fockens.
    Status: Not Checked OutLane Catalog Record
  • 2015 ClinicalKey
    [edited by] Robert H. Hawes, Paul Fockens, Shyam Varadarajulu.
    From diagnostic to therapeutic procedures, Endosonography, 3rd Edition is an easy-to-access, highly visual guide covering everything you need to effectively perform EUS, interpret your findings, diagnose accurately, and choose the best treatment course. World-renowned endosonographers help beginners apply endosonography in staging cancers, evaluating chronic pancreatitis, and studying bile duct abnormalities and submucosal lesions. Practicing endosonographers can learn cutting-edge techniques for performing therapeutic interventions such as drainage of pancreatic pseudocysts and EUS-guided anti-tumor therapy. Meticulous updates, electronic access to the fully searchable text, videos detailing various methods and procedures-and more-equip you with a complete overview of all aspects of EUS. Get a clear overview of everything you need to know to establish an endoscopic practice, from what equipment to buy to providing effective cytopathology services.
  • 2007 Springer
    volume editor, Odd-Arne Olsen.
  • 2010 Springer
    Johannes H.P. Hackstein, editor.
    Free-Living Protozoa with Endosymbiotic Methanogens / Tom Fenchel and Bland J. Finlay -- Anaerobic Ciliates and Their Methanogenic Endosymbionts / Johannes H. P. Hackstein -- Symbiotic Methanogens and Rumen Ciliates / Kazunari Ushida -- The Methanogenic and Eubacterial Endosymbionts of Trimyema / Naoya Shinzato and Yoichi Kamagata -- Termite Gut Flagellates and Their Methanogenic and Eubacterial Symbionts / Yuichi Hongoh and Moriya Ohkuma -- Methanogens in the Digestive Tract of Termites / Andreas Brune -- Methanogenic Archaea in Humans and Other Vertebrates / Everly Conway de Macario and Alberto J. L. Macario -- Methanogens in the Gastro-Intestinal Tract of Animals / Johannes H. P. Hackstein and Theo A. van Alen -- Syntrophy in Methanogenic Degradation / Petra Worm, Nicolai Müller, Caroline M. Plugge, Alfons J. M. Stams and Bernhard Schink -- Hydrogenosomes / Johannes H. P. Hackstein and Aloysius G. M. Tielens -- Evolution of Prokaryote-Animal Symbiosis from a Genomics Perspective / Rosario Gil, Amparo Latorre and Andrés Moya.
  • <2000>
    edited by Leslie J De Groot, editor-in-chief, Paolo Beck-Peccoz, George Chrousos, Kathleen Dungan, Ashley Grossman, Jerome M Hershman, Christian Koch, Robert McLachlan, Maria New, Robert Rebar, Frederick Singer, Aaron Vinik, and Martin O Weickert.
    Endotext (Endotext.org) is an online resource on endocrine disease written by physicians and directed toward physicians around the world caring for patients with these problems. It is organized by Leslie J De Groot, MD, twelve section editors, and nearly 400 authors. It is comprehensive, authoritative, constantly updated, and unbiased. Endotext, covering the broad area of Clinical Endocrinology, emphasizes clinical endocrine practice and includes the most current information on the manifestations of endocrine disease, diagnosis, and treatment.
  • 2007
    edited by William C. Aird.
  • 2014 CRCnetBASE
    editors, Juan A. Rosado, Pedro C. Redondo.
    The endothelial cytoskeleton : multifunctional role of the endothelial actomyosin cytoskeleton / Yuka Shimizu and Joe G.N. Garcia -- Emerging themes on pulmonary microvascular endothelial cell : microtubules and microtubule associated proteins / Cristiaan D. Ochoa, Ron Balczon, and Troy Stevens -- Endothelial actin cytoskeleton and angiogenesis / Sadiqa K. Quadri -- Adherens junctions and endothelial cytoskeleton / Younes Smani and Tarik Smani-Hajami -- Mechanical force transmission via the cytoskeleton in vascular endothelial cells / Bori Mazzag ... [et al.] -- The functional role of the microtubule/microfilament cytoskeleton in the regulation of pulmonary vascular endothelial barrier / Irina B. Alieva and Alexander D. Verin -- Membrane-cytoskeleton interactions and control of vesicle trafficking in endothelial cells / Felicia Antohe -- Cell-matrix adhesion proteins in the regulation of endothelial permeability / Jurjan Aman, Geerten P. van Nieuw Amerongen, and Victor W.M. van Hinsbergh -- Endothelial cells and the regulation of platelet function / P.C. Redondo ... [et al.].
  • 2010 Springer
    Shauna M. Dauphinee, Aly Karsan, editors.
    Also available: Print – 2010
  • 2007
    edited by Raffaele De Caterina, Peter Libby ; foreword by Michael A. Gimbrone Jr.
    Status: Not Checked OutLane Catalog Record
  • 2011 Karger
    volume editors, Matthias Barton, Donald E. Kohan.
  • 2010 Karger
    volume editors, Claudio Ronco, Pasquale Piccinni, Mitchell H. Rosner.
    Endotoxin in the pathogenesis of sepsis / Marshall, J.C. -- Endotoxins and other sepsis triggers / Opal, S.M. -- Rationale of extracorporeal removal of endotoxin in sepsis : theory, timing and technique / Ronco, C., Piccinni, P., Kellum, J. -- Extracorporeal removal of endotoxin : the polymyxin B-immobilized fiber cartridge / Tani, T. ... [et al.] -- Mechanisms of polymyxin B endotoxin removal from extracorporeal blood flow : molecular interactions / Vesentini, S. ... [et al.] -- Mechanisms of polymyxin B endotoxin removal from extracorporeal blood flow : hydrodynamics of sorption / Fiore, G.B. ... [et al.] -- Endotoxin removal by polymyxin B immobilized cartridge inactivates circulating proapoptotic factors / Martin, E.L., Ranieri, V.M. -- Polymyxin-B hemoperfusion and endotoxin removal : lessons from a review of the literature / Cruz, D.N. ... [et al.] -- PMX endotoxin removal in the clinical practice : results from the EUPHAS trial / Antonelli, M. ... [et al.] on behalf of the EUPHAS Study Group -- Early management of endotoxemia using the endotoxin activity assay and polymyxin B-based hemoperfusion / Novelli, G. ... [et al.] -- Endotoxin activity level and septic shock : a possible role for specific anti-endotoxin therapy? / Monti, G. ... [et al.] -- Endotoxin removal : how far from the evidence? : from EUPHAS to EUPHRATES / Rachoin, J.-S. ... [et al.] -- Endotoxin removal : how far from the evidence? : the EUPHAS 2 project / Martin, E.L. ... [et al.].
  • 2010 Springer
    Xiaoyuan Wang, Peter J. Quinn, editors.
    Endotoxins: Lipopolysaccharides of Gram-negative bacteria / X. Wang and P.J. Quinn -- Purification and characterization of lipopolysaccharides / X. Wang ... [et al.] -- Endotoxins: Relationship between structure, function, and activity / K. Brandenburg, A.B. Schromm and T. Gutsmann -- The diversity of the core oligosaccharide in lipopolysaccharides / A. Silipo and A. Molinaro -- Salmonella-regulated lipopolysaccharide modifications / S.M. Richards, K.L. Strandberg and J.S. Gunn -- The variation of O antigens in Gram-negative bacteria / L. Wang, Q. Wang and P.R. Reeves -- Regulators of TLR4 signaling by endotoxins / A.F. McGettrick and L.A.J. O'Neill -- Membrane partitioning: Is location everything when it comes to endotoxin recognition? / M. Triantafilou and K. Triantafilou -- Endotoxin detection - from limulus amebocyte lysate to recombinant Factor C / J.L. Ding and B. Ho -- The role of endotoxin in infection: Helicobacter pylori and Campylobacter jejuni / A.P. Moran -- The role of pseudomonas lipopolysaccharide in cystic fibrosis airway infection / S.M. Moskowitz and R.K. Ernst -- Development of small-molecule endotoxin sequestering agents / S.A. David and D. Sil -- Development of an anti-endotoxin vaccine for sepsis / A.S. Cross -- Synthetic and natural TLR4 agonists as safe and effective vaccine adjuvants / C.B. Fox ... [et al.] -- Targeting endotoxin in the treatment of sepsis / J.-S. Rachoin, C.A. Schorr and R.P. Dellinger -- Lipopolysaccharides in rhizobium-legume symbioses / R.W. Carlson, L.S. Forsberg and E.L. Kannenberg -- Lipopolysaccharides and plant innate immunity / G. Erbs ... [et al.].
  • 2006 Springer
    S. Naito, Y. Hirao, T. Terachi (eds.).
  • 2013 Wiley
    edited by Jacques Kpodonu, Raoul Bonan.
    "Despite the "hot topic" status of this subject, there are few book-length resources that cover the subjects presented here in any depth. There is a particular need for high-quality coverage of hybrid techniques, which have emerged only over the last 3-4 years. Some of the techniques/procedures covered in this book have gained approval and are being used in patient care in Europe and elsewhere and are sure to see approval soon in the United States. Thus, this book not only fills a current need, but also anticipates a very likely near-term need amongst its target audience. The book aims to be a clear, practical guide to the topics covered, and with its combination of text with high-quality still images and videos presented on a companion website it should more than meet the expectations of buyers looking for expert guidance in this area"--Provided by publisher.
  • 2014 Springer
    Robert S. Dieter, Raymond A. Dieter, Jr., Raymond A. Dieter, III, editors.
    Part I: Basic MRI Principles.- A Brief History of Magnetic Resonance Imaging -- Fundamentals of Magnetic Resonance Imaging -- The Relaxation Concept in MRI -- MRI Pulse Sequences -- MR Imaging Parameters and Options -- Part II: MR Safety, Patient Positioning, Protocol Design, Graphical Prescription and MR Applications for Anatomical Regions.- Introduction to Safe Clinical Scanning -- Central Nervous System: MRI Protocols, Imaging Parameters and Graphical Prescriptions -- Musculoskeletal Imaging: MRI Protocols, Imaging Parameters and Graphical Prescriptions -- Body Imaging: MRI Protocols, Imaging Parameters and Graphical Prescriptions -- Cardiovascular Imaging: MRI Protocols, Imaging Parameters and Graphical Prescriptions -- Breast Imaging: MRI Protocols, Imaging Parameters and Graphical Prescriptions.
  • 2015 Springer
    by Aristotelis P. Mitsos.
    Endovascular neurosurgery is a recently introduced but rapidly evolving medical field, which uses minimally invasive interventions to treat major life-threatening vascular lesions of the Central Nervous System. Although its history counts less than 15 years of worldwide acceptance, it has rapidly displaced the traditional open neurosurgical techniques, being nowadays the first treatment choice for brain aneurysms and vascular malformations. Thus, the experience of each neuroendovascular center and performer is invaluable, offering the base for learning and teaching the new generation of interventionalists as well as for the evolvement of the method itself. This book presents the basic principles of endovascular neurosurgery starting from clinical cases. Through this close-to-clinical-reality-process, the reader will be able to more thoroughly understand the pathophysiology of the brain and spine vascular lesions as well as the decision-making strategy, related to the indications, endovascular methods and results, finding suggestions and solutions to his/her clinical questions and problems. Besides chapters devoted to CNS vascular embryology and anatomy, clinical cases organized in groups based on the treated lesions are introduced: ruptured and unruptured cerebral aneurysms of the anterior and posterior circulation, side-wall and bifurcation aneurysms, arteriovenous malformations (AVM), dural arteriovenous fistulae (dAVF), arterial stenosis and angioplasty as well as spinal vascular lesions. A separate chapter is devoted to the organization and necessary equipment of the angio room and the department offering neuroendovascular service. This volume will be of interest to neurosurgeons, interventional neuroradiologists, vascular surgeons, neurologists and ICU physicians as well as health care providers who are involved in the diagnosis and management of the vascular lesions of the brain and spine.
  • 2011 ClinicalKey
    [edited by] Wesley S. Moore, Samuel S. Ahn.
    In the 4th edition, Drs. Wesley S. Moore, Samuel S. Ahn, and a host of experts guide you through the latest developments in this innovative field. New procedures and special features, such as key points and case reviews, help illustrate effective patient care, and new topics such as endoscopic management of aneurismal disease and traumatic injuries review with you the latest endovascular surgical techniques. Broaden your surgical skills with new chapters on endoscopic management of aneurismal disease and traumatic injuries, and review a valuable new section covering the TIPS Procedure for Portal Hypertension, Anesthetic Management for Endovascular Procedures, the Use of Coil Embolization in Endovascular Surgery, and more. An in-depth, core reference on the best practices and techniques in endovascular surgery. Perfect for both the training vascular surgeon who needs a comprehensive view of endovascular surgery as well as a refresher on current techniques and optimal outcomes for the practitioner.
  • 2016 Springer
    Timothy L. Miller, editor.
  • by Anne J. Gilliland-Swetland.
  • 2002 HighWire
    Also available: Print – 2002
  • 2002 HighWire
    Also available: Print – 2002
  • pt. A-E, 1995-2004. ScienceDirect
    pt. B, 1998 ScienceDirect
    pt. C, 2000 ScienceDirect
    pt. D, 2004 ScienceDirect
    pt. E, 2004 ScienceDirect
    Ackers, Gary K.; Holt, Jo M.; Johnson, Michael L.
    Parts [A]-E.
  • v. 1-, 2011- Springer
  • 2012 Springer
    Sanford D. Markowitz, Nathan A. Berger, editors.
    The gastrointestinal track provides one of the distinct systems where multiple malignancies, including adenocarcinoma of the pancreas, esophagus and colon are each associated with obesity. This unique association is covered in this volume of Energy Balance and Cancer from the epidemiologic, biologic and potential etiologic viewpoint. The focus on possible dietary contribution as well as the role of exercise in prevention and therapy is presented in both animal model and patient based studies. Special focus is provided also on the role of genetic mutations and inflammatory pathways as drivers of these obesity related gastrointestinal malignancies. Overall, this volume on Energy Balance and Gastrointestinal Malignancies should be valuable to Epidemiologists, Gastroenterologists and Oncologists, as well as to students and researchers from multiple disciplines interested in understanding and disrupting the association between obesity and cancer.
  • 2012 Springer
    Steven D. Mittelman, Nathan A. Berger, editors.
    The obesity pandemic continues to increase on a world-wide basis with over 70% of the United States population being either overweight or obese. Hematologic malignancies have recently been identified among the obesity associated malignancies spanning the lifespan from childhood to the elderly and include leukemia, myeloma, lymphoma and others. In addition to the etiologic association between obesity and hematologic malignancies, the presence of obesity has profound effects on therapy by impacting pharmacokinetics of chemotherapeutic agents, dose, adipocyte metabolism and drug distribution. These may be particularly important in hematopoietic stem cell transplantation. Another important aspect of the association of obesity with hematologic malignancies is the increased incidence of obesity in children who successfully complete therapy for acute lymphoblastic leukemia. This and other observations indicate important relations between the hematopoietic systems and fat metabolism. This volume on Energy Balance in Hematologic Malignancies will provide an important volume in this series and a basis for better understanding etiology, mechanisms, therapeutics implications and experimental approaches. This volume of energy balance and cancer will focus on the relation of obesity to hematologic malignancies, the epidemiology, potential mechanisms, and thereapeutic considerations including effects on pharmacologic and physical approaches as well as the delayed effects of therapy on energy balance.
  • 2013 Springer
    Klaas R. Westerterp.
    Introduction, Energy Balance in Animals -- Energy Balance -- Limits in Energy Expenditure -- Energy Expenditure, Physical Activity, Body Weight and Body Composition -- Extremes in Energy Intake -- Body Weight -- Growth, Growth Efficiency and Ageing -- Modern Man in Line with Wild Mammals.
  • 2011 ScienceDirect
    edited by David Mayor, Marc S. Micozzi ; foreword by James L. Oschman.
    Qi in Asian medicine / Nancy N. Chen -- Flows and blockages in Rwandan ritual and notions of the body / Christopher C. Taylor -- Elemental souls and vernacular qi : some attributes of what moves us / David Mayor -- The anatomical foundations of qi / John L. Stump -- Qi in China's traditional medicine : the example of tuina / Kevin V. Ergil and Marc S. Micozzi -- Qi cultivation in qigong and taiji quan / Gideon Enz -- Qigong theory and research / Amy L. Ai -- The language of qi, quantum physics, and the superimplicate body / F. David Peat -- Qi and the frequencies of bioelectricity / Cyril W. Smith -- Systems theory : trapping and mapping healing with qi / Christopher Low -- The physiology of qi / Hakima Amri and Mones S. Abu-Asab -- Energy and medicine / John A. Ives and Wayne B. Jonas -- What does it mean to practice an energy medicine? / Claire M. Cassidy -- Evidencing energy : experiences in acupuncture and therapeutic bodywork (zero balancing) / Tim Newman -- Eight modalities for working with qi : chakra acupuncture, with qigong, meditation, and the five sources of energy / Gabriel Stux -- Ki in shiatsu / Patrizia Stefanini -- Bioelectricity and qi : a microcurrent approach / Darren Starwynn -- Energy psychology : working with mind-body synergy / Phil Mollon -- Craniosacral biodynamics / Franklyn Sills -- Qi in children / May Loo -- Qigong, taiji quan (tai chi) and HIV : the psychoneuroimmunology connection / Mary Lou Galantino and Laura Muscatello -- Energy-based therapies in neurology : the example of therapeutic touch / Eric Leskowitz -- Qi in chronic fatigue and fibromyalgia / Carolyn McMakin and Peter H. Fraser -- The electrical heart : energy in cardiac health and disease / Alan Watkins -- Themes of qi and a dozen definitions : content analysis and discussion / David Mayor and Marc S. Micozzi.
  • 2008 Springer
    edited by Patricia A. Donohoue.
    Molecular Physiology of Monogenic and Syndromic Obesities in Humans / Wendy K. Chung and Rudolph L. Leibel -- Leptin Signaling In the Brain / Ofer Reizes, Stephen C. Benoit, and Deborah J. Clegg -- Inactivating Melanocortin-4 Receptor Mutations and Human Obesity / Ya-Xiong Tao -- The Role of Central Melanocortins in Cachexia / Daniel L. Marks -- The Efferent Arm of the Energy Balance Regulatory Pathway: Neuroendocrinology and Pathology / Robert H. Lustig -- Adiponectin: A Multifunctional Adipokine / Kristen Clarke and Robert L. Judd -- The Role of the Gastrointestinal Hormones Ghrelin, Peptide YY and Glucagon-like Peptide-1 in the Regulation of Energy Balance / Ruben Nogueiras, Hilary Wilson, Diego Perez-Tilve and Matthias H. Tschöp -- The Role of Growth Hormone Secretagogues and Ghrelin in Feeding and Body Composition / Cyril Y. Bowers, Blandine Laferrère, David Hurley, and Johannes D. Veldhuis -- Interaction Between Physical Activity and Genetic Factors in Complex Metabolic Disease / Paul W. Franks and Stephen M. Roth -- 11ss-Hydroxysteroid Dehydrogenase Type 1 and Obesity / Roland H. Stimson and Brian R. Walker -- Prader-Willi Syndrome : A Model of Disordered Energy Homeostasis / Andrea Haqq -- Antipsychotic Medication-Induced Weight Gain and Risk for Diabetes and Cardiovascular Disease / John W. Newcomer -- Treatment of Insulin Resistance in Youth: The Role of Metformin / Molly Emott and Michael Freemark -- The Surgical Approach to Morbid Obesity / Edward E. Mason, Mohammad K. Jamal and Thomas O'Dorisio.
  • 1944-
    por el Dr. Rodolfo V. Talice ...
    Status: Not Checked OutLane Catalog Record
  • 2015 healthaffairs.org
    written by Sarah Goodell.
    Five years after the Mental Health Parity and Addiction Equity Act took effect, access to equal benefits and qualified providers remains elusive for many insured Americans.
  • 2010 Springer Protocols
    edited by Joel P. Mackay, David J. Segal.
    The generation of zinc finger proteins by modular assembly / Mital S. Bhakta and David J. Segal -- Engineering single Cys2His2 zinc finger domains using a bacterial cell-based two-hybrid selection system / Stacey Thibodeau-Beganny, Morgan L. Maeder, and J. Keith Joung -- Bipartite selection of zinc fingers by phage display for any 9-bp DNA target site / Jia-Ching Shieh -- Structure-based DNA-binding prediction and design / Andreu Alibés, Luis Serrano, and Alejandro D. Nadra -- Generation of cell-permeable artificial zinc finger protein variants / Takashi Sera -- Inhibition of viral transcription using designed zinc finger proteins / Kimberley A. Hoeksema and D. Lorne J. Tyrrell -- Modulation of gene expression using zinc finger-based artificial transcription factors / Sabine Stolzenburg ... [et al.] -- Construction of combinatorial libraries that encode zinc finger-based transcription factors / Seokjoong Kim, Eun Ji Kim, and Jin-Soo Kim -- Silencing of gene expression by targeted DNA methylation : concepts and approaches / Renata Z. Jurkowska and Albert Jeltsch -- Remodeling genomes with artificial transcription factors (ATFs) / Adriana S. Beltran and Pilar Blancafort -- Transgenic mice expressing an artificial zinc finger regulator targeting an endogenous gene / Claudio Passananti ... [et al.] -- Artificial zinc finger nucleases for DNA cloning / Vardit Zeevi, Andriy Tovkach, and Tzvi Tzfira -- In vitro assessment of zinc finger nuclease activity / Toni Cathomen and Cem Șöllü -- Quantification of zinc finger nuclease-associated toxicity / Tatjana I. Cornu and Toni Cathomen -- A rapid and general assay for monitoring endogenous gene modification / Dmitry Y. Guschin ... [et al.] -- Engineered zinc finger proteins for manipulation of the human mitochondrial genome / Michal Minczuk -- High-efficiency gene targeting in Drosophila with zinc finger nucleases / Dana Carroll, Kelly J. Beumer, and Jonathan K. Trautman -- Using zinc finger nucleases for efficient and heritable gene disruption in zebrafish / Jasmine M. McCammon and Sharon L. Amacher -- A transient assay for monitoring zinc finger nuclease activity at endogenous plant gene targets / Justin P. Hoshaw ... [et al.] -- Validation and expression of zinc finger nucleases in plant cells / Andriy Tovkach, Vardit Zeevi, and Tzvi Tzfira -- Non-FokI-based zinc finger nucleases / Miki Imanishi, Shigeru Negi, and Yukio Sugiura -- Designing and testing chimeric zinc finger transposases / Matthew H. Wilson and Alfred L. George -- Seeing genetic and epigenetic information without DNA denaturation using sequence-enabled reassembly (SEER) / Jason R. Porter ... [et al.] -- Zinc finger-mediated live cell imaging in Arabidopsis roots / Beatrice I. Lindhout, Tobias Meckel, and Bert J. van der Zaal -- Biophysical analysis of the interaction of toxic metal ions and oxidants with the zinc finger domain of XPA / Andrea Hartwig, Tanja Schwerdtle, and Wojciech Bal -- Preparation and zinc-binding properties of multi-fingered zinc-sensing domains / John H. Laity and Linda S. Feng -- Using ChIP-seq technology to identify targets of zinc finger transcription factors / Henriette O'Geen, Seth Frietze, and Peggy J. Farnham -- Crystallization of zinc finger proteins bound to DNA / Nancy C. Horton and Chad K. Park -- Beyond DNA : zinc finger domains as RNA-binding modules / Josep Font and Joel P. Mackay.
  • 2014 Springer Protocols
    edited by Lianhong Sun, Wenying Shou.
    Recent progress in engineering human-associated microbiomes / Stephanie J. Yaung, George M. Church, and Harris H. Wang -- Constructing synthetic microbial communities to explore the ecology and evolution of symbiosis / Adam James Waite and Wenying Shou -- Combining engineering and evolution to create novel metabolic mutualisms between species / Lon Chubiz, Sarah Douglas, and William Harcombe -- Design, construction, and characterization methodologies for synthetic microbial consortia / Hans C. Bernstein and Ross P. Carlson -- An observation method for autonomous signaling-mediated synthetic diversification in Escherichia coli / Ryoji Sekine, Shotaro Ayukawa, and Daisuke Kiga -- Integration-free reprogramming of human somatic cells to induced pluripotent stem cells (iPSCs) without viral vectors, recombinant DNA, and genetic modification / Boon Chin Heng and Martin Fussenegger -- Transformation of Bacillus subtilis / Xiao-Zhou Zhang, Chun You, and Yi-Heng Percival Zhang -- Culturing anaerobes to use as a model system for studying the evolution of syntrophic mutualism / Sujung Lim, Sergey Stolyar, and Kristina Hillesland -- Therapeutic microbes for infectious disease / Choon Kit Wong [and six others] -- Quantitative measurement and analysis in a synthetic pattern formation multicellular system / Xiongfei Fu and Wei Huang -- Transcriptome analysis of a microbial coculture in which the cell populations are separated by a membrane / Kazufumi Hosoda [and three others] -- Identification of mutations in laboratory-evolved microbes from next-generation sequencing data using breseq / Daniel E. Deatherage and Jeffrey E. Barrick -- 3D-fluorescence in situ hybridization of intact, anaerobic biofilm / Kristen A. Brileya, Laura B. Camilleri, and Matthew W. Fields -- The characterization of living bacterial colonies using nanospray desorption electrospray ionization mass spectrometry / Brandi S. Heath, Matthew J. Marshall, and Julia Laskin -- Modeling community population dynamics with the open-source language R / Robin Green and Wenying Shou -- Simulating microbial community patterning using Biocellion / Seunghwa Kang, Simon Kahan, and Babak Momeni.
  • 2013
    Monica Elise Ortiz.
    Evolution has selected for organisms that benefit from genetically encoded cell-cell communication. We observe cell-cell communication throughout every scale in nature, from simple single-celled bacteria to complex multicellular mammals. Engineers have begun to repurpose elements of natural communication systems to coordinate their own population-level behaviors, including oscillations and programmed pattern formation. Existing engineered systems, however, rely on small, system-specific biomolecules to send messages among cells. However, such molecules are capable of sending only a single message, typically "regulate transcription.'' Thus, the information transmission capacity of such biological communication systems is fundamentally limited. Through this thesis, I demonstrated the decoupling of messages from a common communication channel via the autonomous transmission of numerous arbitrary genetic messages. To do so, I engineered a cell-cell communication platform using bacteriophage M13 gene products to autonomously package and deliver heterologous DNA messages of varying lengths and encoded functions. Further, I increased the range of engineered DNA messaging across semisolid media by coupling message transmission or receipt to active cellular chemotaxis. Through this coupling, I demonstrated that our system is adaptable to different contexts by creating simple patterns. Finally, using recombinase-mediated logic gates developed within the Endy laboratory, I demonstrated the ability to program bacteria by transmitting logic gates to surrounding cells. Overall, this work significantly enhances the suite of cell-cell communication tools available to engineers. I have shown that a variety of DNA messages can be transmitted among cells and have moved the field of synthetic biology closer to designing synthetic ecologies with more complex communication schemes and varied behaviors.
  • 2012
    Sarah Jean Moore.
    Proteins and peptides are an incredibly versatile class of biological molecules, with a vast array of naturally occurring functions. In cancer, the natural roles of proteins become incorrectly regulated, and the presence of cancer-related proteins on tumor cells can be detected and targeted for diagnosis and treatment. This thesis decribes novel engineered peptides for molecular recognition of cell surface receptors expressed in cancers, and application of these engineered peptides as diagnostic agents to identify solid tumors in mouse models. For this work. three different cystine-knot peptides were used for development and engineering: Agatoxin (AgTx), Agouti-related protein (AgRP), and Ecballium elaterium trypsin inhibitor-II (EETI). In addition, two protein receptors were employed as model tumor targets relevant for molecular imaging of cancer: carbonic anhydrase IX (CA IX) and tumor associated integrin receptors. New methods were developed towards engineering AgTx and AgRP to bind CA IX, and work to produce these peptides for further study and their limitations are described. In a parallel line of research, to further understand the promise of using knottin peptides in cancer imaging, the influence of amino acid loops on tissue biodistribution was examined using engineered AgTx, AgRP, and EETI peptides that bind tumor target integrins in mouse xenograft models. Finally, an engineered EETI knottin peptide that binds tumor-associated integrins was shown to specifically target and illuminate brain tumors in mouse models of medulloblastoma. Importantly, the protein engineering methods and molecular imaging applications described here have promise for influencing the clinical outcome of cancer patients through image-guided surgical resection, disease staging and management, and monitoring the effectiveness of therapeutic treatments.
  • 2015 Springer
    Luiz E. Bertassoni, Paulo G. Coelho, editors.
    This book offers a comprehensive overview of current challenges and strategies to regenerate load-bearing and calcified human tissues, including bone, cartilage,tendon, ligaments and dental structures (dentin, enamel, cementum and periodontal ligament). Tissue engineering has long held great promises as an improved treatment option for conditions affecting mineralized and load-bearing structures in the body. Although significant progress has been achieved in recent years, a number of challenges still exist. Scaffold vascularization, new biofabrication methods (3D printing, lithography, microfabrication), peptide conjugation methods, interface engineering, scaffold mechanical properties, iPS cells, organs-on-a-chip, are some of the topics discussed in this book. More specially, in the first section readers will find an overview of emerging biofabrication methods. In section 2, applied strategies for regeneration of (2.1) bone, cartilage and ligament, as well as (2.2) dentin, cementum, enamel and periodontal ligament are discussed across 14 chapters. While other volumes have addressed the regeneration of individual tissues, or exclusively focused on different regenerative strategies, the focus of this work is to bring together researchers integrating backgrounds in materials sciences, engineering, biology, mechanics, fluidics, etc, to address specific challenges common to regeneration of several load-bearing and calcified tissues. Therefore, this book provides a unique platform to stimulate progress in the regeneration of functional tissue substitutes. We envision that this book will represent a valuable reference source for university and college faculties, post-doctoral research fellows, senior graduate students, and researchers from R&D laboratories in their endeavors to fabricate biomimetic load bearing tissues.
    Also available: Print – 2015
  • 2012
    Jay Thomas Fitzgerald.
    Polyketides are a large class of structurally diverse natural products which posses a wide range of biological activities. Unfortunately, despite the potential utility of these compounds in the clinic, large scale production of many of these natural products from their native hosts remains a challenge. Additionally, due to their complexity, engineering better pharmacokinetic properties by traditional synthetic means is often challenging. A better understanding of the biosynthetic machinery which produces polyketides allows for optimization of their production and paves the way for bioactivity-based pathway reengineering. This work begins with an introduction detailing attempts to unravel the biosynthetic underpinnings of two key natural product families, the tetracyclines and the thiostreptons, with an eye toward ultimately reengineering the pathways. Then, our efforts to reconstruct and reengineer the biosynthesis and biological activity of the type II polyketides frenolicin and A-74528 are detailed. Successful reconstruction of a chimeric biosynthetic pathway to frenolicin B and subsequent reengineering of that pathway to produce novel frenolicin analogs is described. Then, the biological activity of these compounds both in vitro against the parasites Toxoplasma gondii and Plasmodium falciparum is discussed. Additional studies against Plasmodium berghi in mice show that frenolicin B is an effective antiparastic agent in vivo. Following this, engineering of a biosynthetic pathway to the novel antiviral agent A-74528 from S. sp. SANK 61196 is presented and the impact of various tailoring enzymes on metabolite production are explored.
  • 2011
    Sheng Ding.
    Recombinant proteins have been used widely in both basic research and biomedical applications including protein therapeutics and biomaterials. Many efforts have been devoted to the investigation of novel synthetic strategies for producing recombinant proteins for various applications, which is the focus of this dissertation. In the first section, a biosynthetic strategy was developed to produce collagenous proteins with post-translational modifications in E. coli. Collagen is the most abundant protein in human, and plays a dominant role in maintaining the biological and structural integrity. Recombinant expression of collagens and fragments of collagens is often difficult as their stability requires appropriate proline hydroxylation. Prolyl 4-hydroxylases (P4H) are ascorbate-dependent oxygenases that play key roles in collagen folding by catalyzing the post-translational hydroxylation of specific proline residues on target proteins to form (2S, 4R)-4-hydroxyproline. Thus far, the study of these post-translational modifications has been limited by the lack of a prokaryotic recombinant expression system for producing hydroxylated proteins. Unlike eukaryotic cells such as yeast and insect cells, bacterial cytoplasm cannot activate P4H, which requires an ascorbate co-factor that bacteria do not produce. By introducing a biosynthetic shunt to produce ascorbate-like molecules in E. coli cells that heterologously express human P4H, we have created a strain of E. coli that produces collagenous proteins with (2S, 4R)-4-hydroxyproline. Different levels of proline hydroxylation can be obtained by tuning culture conditions. We have verified that hydroxylation of collagenous materials produced in the new system leads to an increase in thermostability. Using this new system, we have observed hydroxylation patterns indicative of a processive catalytic mode for P4H that is active even in the absence of ascorbate. Our results provide insights into P4H enzymology, and create a foundation for better understanding how post-translational hydroxylation affects proteins. Further, we applied the novel E. coli expression system to produce a collagenous protein, adiponectin, which has many beneficial effects on obesity-related metabolic and cardiovascular disorders, and reverses insulin insensitivity. By introducing key post-translational modification enzymes to E. coli, we have endowed the expression system with capabilities of making necessary modifications on adiponectin for its correct assembly, and thus obtained biomimetic adiponectins. High-molecular weight (HMW) multimers of adiponectin have been obtained, and their biological activities of suppressing endothelial cell apoptosis have been confirmed with in vitro cell assays. In section 2, modular protein polymers have been created through genetic engineering and enzymatically crosslinked into hydrogels with tunable properties. The many challenges currently faced in regenerative medicine research require the development of new, modular biomaterial systems that can serve as scaffolds for cellular maintenance, expansion and growth, and which can be tuned by the user to mimic any necessary aspects of natural ECM to an optimal degree. Toward this goal, we have created a family of block co-polypeptides comprising amino acid sequence elements that allow mild enzymatic crosslinking into gels. These new families of protein polymers were designed to be linear, random coil, and contain either lysine or glutamine, which have the recognition substrates for transglutaminase (TG) crosslinking, evenly spaced along the protein backbone. Crosslinking occurred within two minutes upon the addition of TG under physiological conditions, as determined by particle tracking microrheology. The material properties of the gel can be tuned with the hydrogel composition to mimic cellular microenvironment of different tissues. Furthermore, in order to introduce biofunctionalities into the hydrogels, a versatile expression vector has been engineered that allows the insertion of bioactive protein domains into these block co-polypeptide. For example, a cell adhesion signal based on the RGD sequence from human fibronectin was incorporated. The RGD-containing hydrogel was successful in enhancing cell adhesion, and were also proven to be compatible with the culture of mesenchymal stem cells. The specific nature of these protein polymer precursors of the modular hydrogel composition allows tailoring of mechanical and biochemical properties, rendering these gels valuable for various tissue engineering applications.
  • 2007 Springer
    Felix Bronner, Mary C. Farach-Carson and Antonios G. Mikos (eds.).
  • 2014 Wiley
    edited by Rebecca A. Bader, David A. Putnam.
    Polymers have played a critical role in the rational design and application of drug delivery systems that increase the efficacy and reduce the toxicity of new and conventional therapeutics. Beginning with an introduction to the fundamentals of drug delivery, Engineering Polymer Systems for Improved Drug Delivery explores traditional drug delivery techniques as well as emerging advanced drug delivery techniques. By reviewing many types of polymeric drug delivery systems, and including key points, worked examples and homework problems, this book will serve as a guide to for specialists and non-
  • 2005 CRCnetBASE
    Allan Chapman.
  • 2009 Springer
    Ramón Ribes, Palma Iannarelli, Rafael F. Duarte.
  • 2007
    Glenn T. Rogers.
    Status: Not Checked OutLane Catalog Record
  • 2007 CRCnetBASE
    edited by Elka Touitou, Brian W. Barry.
  • 2011 Springer
    Paula E. Hartman-Stein, Asenath La Rue, editors.
    Memory Enhancement Strategies: What Works Best for Obtaining Memory Goals? -- Mental and Physical Exercise as a Means to Reverse Cognitive Aging and Enhance Well-Being -- Consumer-Based Brain Fitness Programs -- Synapse: A Clinical Trial Examining the Impact of Actively Engaging the Aging Mind -- Meditation, Mindfulness, Cognition, and Emotion: Implications for Community-Based Older Adult Programs -- Keys to a Sharp Mind: Providing Choice and Quality Programming in a Retirement Community -- Osher Lifelong Learning Institute at the University of Montana: A Model of Successful University and Community Partnerships -- Closing the Generation Gap: Using Discussion Groups to Benefit Older Adults and College Students -- A Practical Guide to Senior Odyssey -- Spelling Clubs and Competitions for Older Adults: Language Boosting Within a Social Context -- Oral Life Review in Older Adults: Principles for the Social Service Professional -- Creative Writing Groups: A Promising Avenue for Enhancing Working Memory and Emotional Well-Being -- Peer-Led Memory Training Programs to Support Brain Fitness -- Cognitive Wellness for Diverse Populations -- The Role of Physical Activity in Cognitive Fitness: A General Guide for Community Programs -- Nutrition and Nutritional Supplements to Promote Brain Health -- Enhancing Healthy Cognitive Aging Through Theater Arts -- Coming Alive: Kairos Dance Theatre's Dancing Heart[TM] - Vital Elders Moving in Community -- Art, Museums, and Culture -- The Songwriting Works[TM] Model: Enhancing Brain Health and Fitness Through Collaborative Musical Composition and Performance -- Supporting Cognition and Well-Being in Older Adults with Mild Cognitive Impairment: A Pilot Intervention -- Early Memory Loss Clubs: A Novel Approach for Stimulating and Sustaining Cognitive Function -- Implementing the "I'm Still Here"[TM] Approach: Montessori-Based Methods for Engaging Persons with Dementia -- Kirtan Kriya Meditation: A Promising Technique for Enhancing Cognition in Memory-Impaired Older Adults -- Brain Brightening: Neurotherapy for Enhancing Cognition in the Elderly -- Neurons in Neighborhoods: How Purposeful Participation in a Community-based Intergenerational Program Enhanced Quality of Life for Persons Living with Dementia -- Experience Corps®: A Civic Engagement-Based Public Health Intervention in the Public Schools.
  • 2013 Springer
    Durriyah Sinno, Lama Charafeddine, Mohamad Mikati ; with contributions by Rebecca L. Holt, Aravindhan Veerapandiyan.
    Rationale for developmental interventions in children -- Enhancing childhood development in a normal child -- Enhancing childhood development in children with autism -- Enhancing childhood development in children with cerebral palsy and other disorders -- Enhancing childhood development in children with behavioral and psychological disorders -- Nutrition for better development -- Summary of the "Care for Childhood Development" program (UNICEF/WHO).
  • 2012 Springer
    editor: Hayden B. Bosworth.
    Enhancing Medication Adherence: The Public Health Dilemma is a comprehensive guide to medication adherence for the healthcare professional. Clinicians and pharmacists alike can benefit from key opinion leader and author Hayden Bosworth's text as he explains the details and causes behind medication nonadherence as well as methods on how healthcare providers can determine if a patient is nonadherent. Additionally, Bosworth discusses various studies, which assess adherence, adherence-related technology, best practices for clinicians and pharmacists, and future directions and recommendations in the field.
  • pt. 1-2, 2011. ScienceDirect
    pt. 2 ScienceDirect
    edited by Andrea M. Green ... [et al.].
  • 2013
    edited by Thomas S. Inui and Richard M. Frankel.
    Status: Not Checked OutLane Catalog Record
  • 2006 Springer
    Riccardo Lencioni (ed.).
    Also available: Print – 2006
  • 2011 WHO
    Introduction to the guidelines. Purpose, target and scope -- Background -- A dual obligation, a quadruple imperative -- Indispensability of controlled medicines in contemporary medical practices -- Safety of controlled medicines -- Current availability -- Impediments to availability, accessibility and affordability -- Why and how to work with this document? -- Guidelines for ensuring balance in national policies on controlled substances. Content of drug control legislation and policy -- Authorities and their role in the system -- Policy planning for availability and accessibility -- Healthcare professionals -- Estimates and statistics -- Procurement -- Other -- Country assessment checklist.
    Also available: Print – 2011
  • 2016
    Steve Olson, rapporteur ; Forum on Promoting Children's Cognitive, Affective, and Behavioral Health, Board on Children, Youth, and Families, Division of Behavioral and Social Sciences and Education, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine.
    "Children with disabilities and complex medical and educational needs present a special challenge for policy makers and practitioners. These children exhibit tremendous heterogeneity in their conditions and needs, requiring a varied array of services to meet those needs. Uneven public and professional awareness of their conditions and a research base marked by significant gaps have led to programs, practices, and policies that are inconsistent in quality and coverage. Parents often have to navigate and coordinate, largely on their own, a variety of social, medical, and educational support services, adding to the already daunting financial, logistical, and emotional challenges of raising children with special needs. The unmet needs of children with disabilities and complex medical and educational needs can cause great suffering for these children and for those who love and care for them. To examine how systems can be configured to meet the needs of children and families as they struggle with disabilities and complex health and educational needs, the National Academies of Sciences, Engineering, and Medicine held a workshop in December 2015. The goal of the workshop was to highlight the main barriers and promising solutions for improving care and outcome of children with complex medical and educational needs. Workshop participants examined prevention, care, service coordination, and other topics relevant to children with disabilities and complex health and educational needs, along with their families and caregivers. More broadly, the workshop seeks actionable understanding on key research questions for enhancing the evidence base; promoting and sustaining the quality, accessibility, and use of relevant programs and services; and informing relevant policy development and implementation. By engaging in dialogue to connect the prevention, treatment, and implementation sciences with settings where children are seen and cared for, the forum seeks to improve the lives of children by improving the systems that affect those children and their families. This publications summarizes the presentations and discussions from the workshop"--Publisher's description.
  • 2014 CRCnetBASE
    George Mochloulis, F. Kay Seymour, Joanna Stephens.
    1. Grommet insertion -- 2. Removal of lesion from pinna : wedge excision -- 3. Excision of preauricular sinus -- 4. Myringoplasty -- 5. Ossiculoplasty -- 6. Stapedotomy -- 7. Mastoidectomy and canalplasty -- 8. Cochlear implantation -- 9. Manipulation under anaesthesia of fractured nose -- 10. Septoplasty -- 11. Surgery to inferior turbinates -- 12. Endoscopic sphenopalatine artery ligation -- 13. Anterior ethmoidal artery ligation -- 14. Functional endoscopic sinus surgery (FESS) -- 15. Septorhinoplasty -- 16. Lateral rhinotomy and medial maxillectomy -- 17. Maxillectomy -- 18. Endoscopic dacryocystorhinostomy -- 19. External carotid artery ligation -- 20. Midfacial degloving -- 21. Fine needle aspiration cytology -- 22. Lymph node biopsy -- 23. Tonsillectomy and adenoidectomy -- 24. Uvulopalatoplasty -- 25. Tracheostomy -- 26. Diagnostic procedures in the upper aerodigestive tract -- 27. Paediatric microlaryngoscopy and bronchoscopy (MLB) foreign body removal -- 28. Phonosurgery -- 29. Microlaryngoscopy and laser use -- 30. Pharyngeal pouch -- 31. Submandibular gland excision -- 32. Superficial parotidectomy -- 33. Thyroglossal cyst excision -- 34. Thyroidectomy -- 35. Neck dissection -- 36. Total laryngectomy -- 37. Pectoralis major myocutaneous flap -- 38. Local flaps -- 39. Pinnaplasty -- 40. Blepharoplasty -- 41. Face lift.
  • 2014 Springer
    edited by Fred Lin, Zara Patel.
    ENT Board Prep is a high-yield review that is an ideal study guide for the ENT in-service and board exams. While other review guides are low yield or more of a textbook, this is quick, concise, and easy-to-use, providing everything you need to know in a easy to digest format. ENT Board Prep offers review on sections such as cancer, ear, sinus, plastics, sleep, and laryngology, as well as case studies useful for studying for the oral board exams. Written and edited by leaders in the field, this book aims to serve future residents and fellows in those crucial weeks leading up to the ENT board exam.
  • 2016 ClinicalKey
    [edited by] Melissa A. Scholes, Vijay R. Ramakrishnan.
  • 2006
    John Barton Furness.
    Status: Not Checked OutLane Catalog Record
    The enteric plexuses -- Interconnections between the plexuses -- Extent of the ganglionated plexuses -- Intramural extensions of extrinsic nerves -- Electron microscope studies -- Enteric glia -- The structural similarities and functional differences between regions may have an evolutionary basis -- Development of the enteric nervous system -- Maturation of enteric neurons and development of function -- Changes in enteric neurons with aging -- Summary and conclusions -- Shapes of enteric neurons -- Cell physiological classifications of enteric neurons -- Functionally defined enteric neurons -- Neurons in human intestine with equivalence to those investigated in laboratory animals -- Summary and conclusions -- Evolution of ideas about enteric circuitry -- Motility controlling circuits of the small and large intestine -- Intrinsic secretomotor and vasomotor circuits -- Assemblies of neurons -- Circuits in the esophagus and stomach -- Co-ordination of motility, secretomotor and vasomotor reflexes -- Circuits connecting the intestine, biliary system and pancreas -- Sympathetic innervation of the gastrointestinal tract -- Summary and conclusions -- Chemical coding and multiple transmitters -- Transmitters of motor neurons that innervate the smooth muscle of the gut -- Transmitters at neuro-neuronal synapses -- Sites within the reflex circuitry where specific pharmacologies of transmission can be deduced to occur -- Transmission from entero-endocrine cells to IPANs -- Roles of interstitial cells of Cajal in neuromuscular transmission -- Transmitters of secretomotor and vasodilator neurons -- Synapses in secretomotor and vasodilator pathways -- Transmitters of motor neurons innervating gastrin cells -- Summary and conclusions -- Rhythmic activity of gastrointestinal muscle -- Structure and properties of interstitial cells of cajal -- Relationship between slow wave activity and neural control -- Gastric motility -- Patterns of small intestine motility and their intrinsic neural control -- Motility of the colon -- Neural control of the esophagus -- Gall-bladder motility -- Sphincters -- Muscle of the mucosa -- Mechanism of sympathetic inhibition of motility in non-sphincter regions -- Sympathetic innervation of the sphincters -- Physiological effects of noradrenergic neurons on motility in undisturbed animals -- Reflex activities of sympathetic neurons that affect motility -- Summary and conclusions -- Water and electrolyte secretion in the small and large intestines -- Reflex control of water and electrolyte secretion -- Secretion of gastric acid -- Pepsinogen secretion -- Gastric secretion of bicarbonate -- Secretion into the gall bladder -- Pancreatic exocrine secretion -- Summary and conclusions -- Therapeutic endpoints for motility disorders -- Therapies for secretory diarrheas -- Enteric neuropathies involving neuronal loss or phenotypic changes -- Mitochondriopathies with intestinal manifestations -- Irritable bowel syndrome and plasticity of enteric neurons -- Summary and conclusions.
  • 2016 Springer
    Stuart Brierley, Marcello Costa, editors.
    Memories and promises of the enteric nervous system and its functions / Marcello Costa -- A personal perspective on the development of our understanding of the myogenic control mechanisms of gut motor function / Jan D. Huizinga -- Enteric inhibitory neurotransmission, starting down under / Kenton M. Sanders -- Spatiotemporal mapping and the enteric nervous system / Grant W. Hennig -- Development of neural activity in the Enteric nervous system: similarities and differences to other parts of the nervous system / Marlene M. Hao -- ENS development research since 1983: great strides but many remaining challenges / Heather M. Young, Lincon A. Stamp, and Sonja J. McKeown -- Extrinsic sensory innervation of the gut: structure and function / Simon Brookes, Nan Chen, Adam Humenick, Nick Spencer, and Marcello Costa -- Ageing and gastrointestinal sensory function / Christopher Keating and David Grundy -- Altered ion channel/receptor expression and function in extrinsic sensory neurons: the cause of and solution to chronic visceral pain? / Stuart Brierley -- Purinergic signalling in the gut / Geoffrey Burnstock -- Is there a role for endogenous 5-HT in gastrointestinal motility? How recent studies have changed our understanding / Nick J. Spencer and Damien J. Keating -- Enteric neuropathies: Yesterday, today and tomorrow / Robert De Giorgio, Francesca Bianco, Rocco Latorre, Giacomo Caio, Paolo Clavenzani, and Elena Bonora -- Postnatal development of the mouse enteric nervous system / Jaime Pei Pei Foong -- G protein-coupled receptor trafficking and signalling in the enteric nervous system: the past, present and future / David P. Poole and Nigel W. Bunnett -- The intrinsic reflex circuitry of the inflamed colon / Gary M. Mawe and Keith A. Sharkey -- Integrated neural and endocrine control of gastrointestinal function / John B. Furness -- Enteric neurobiology: discoveries and directions / Jackie D. Wood -- Advanced 3D optical microscopy in ENS research / Pieter Vanden Berghe -- Excitability and synaptic transmission in the enteric nervous system: Does diet play a role? / Paul B. Bertrand, Kate E. Polglaze, Hui Chen, Shaun L. Sandow, Anna Walduck, Trisha A. Jenkins, Rebecca L. Bertrand, Alan E. Lomax, and Lu Liu -- Recording in vivo human colonic motility: what have we learnt over the past 100 years? / Phil G. Dinning -- Letters -- Index.
    Also available: Print – 2016
  • 2006
    Status: Not Checked OutLane Catalog Record
    Enterobacter sakazakii and Salmonella are the primary pathogens of concern with regard to powdered infant formula. Guidance for the control of these hazards is currently being developed by Codex Alimentarius through the revision of the Recommended International Code of Hygienic Practices for Foods for Infants and Children. FAO and WHO are providing the scientific advice to facilitate this work. FAO and WHO implemented the first meeting on this issue in 2004, the outcome of which is reported in number six of this series. This report builds on the information and advice provided in 2004.
  • 2008
    Status: Not Checked OutLane Catalog Record
    This report provides a review of commented Entrobacter sakazakii (Cronobacter spp.) infections worldwide in infants and young children as well as the existing surveillance systems and their capacity to capture cases of E. sakazakii (Cronobacter spp.) infection.--Publisher's description.
  • Dan Chak.
  • Google Books
    Sabouraud, R.
    Also available: Print – v. 1, 1922.
  • 2013
    David Halladin.
    This thesis examines three topics that are related to the Gram-positive bacterial cell envelope. First, I examine how transmembrane proteins navigate through the thick, heavily cross-linked Gram-positive cell wall while remaining anchored to the bacterial membrane. I develop a theoretical model that predicts that entropic confinement of a disordered protein can drive translocation through the cell wall. I experimentally test important predictions of the model to demonstrate that translocation depends on the length of the translocating protein and the geometry of the bacterial surface, while demonstrating that entropy-driven translocation occurs in a variety of Gram-positive species. Second, I study how the antimicrobial peptide nisin causes cell death in Gram-positive bacteria. I demonstrate that nisin treatment triggers membrane collapse in multiple Gram-positive species, and provide evidence that collapse is initiated by an increase in compressive stress in the membrane. Finally, I examine the process of cell division in the Gram-positive coccus Staphylococcus aureus. Contrary to the current view of S. aureus division, cell volume increases monotonically during the cell cycle, as opposed to occurring entirely during cell separation. I observed a dramatic millisecond hemisphere-to-sphere transition during cell separation that was accompanied by a decrease in surface area, suggesting that separation is associated with a redistribution of cell wall stress.
  • 2007 Springer
    edited by Jacqueline D. Reeves and Cynthia A. Derdeyn.
  • 2010
    Sarah Mercedes Ramirez.
    "Enumerating Invisibility, Humanizing Numbers: Public Health and the Production of Inequities 1938-1974" is directed at answering one question: Why in spite of intensive study that has resulted in a wealth of numerical and statistical information on public health does the San Joaquin Valley and the residents therein remain, among one of the most underfunded, overlooked, impoverished and unhealthy regions? Through an examination of historical materials-- surveys, reports, occupational surveillance, and decision making-- this dissertation seeks to better understand how data and policy, through the social processes of classification and quantification, may have contributed to the production of inequities in the San Joaquin Valley. There are few studies to date that systematically examine the relationship between knowledge and numbers and even fewer that address the concerns of frequently overlooked communities of agricultural laborers in the San Joaquin Valley. This dissertation begins to fill these gaps by reviewing a diverse array of source material to trace how institutions counted and measured agricultural laborers, how the institutions shaped these counting practices, and how numbers shaped policies. Given that institutional identities and strategies of governance are at stake in the production of these numbers, the story of agricultural laborers their health, social, and scientific visibility must be told alongside the stories of state bureaucracies. In tracing how institutions counted and measured agricultural laborers, how the institutions shaped these counting practices, how numbers shaped policies and decisions, there is an opportunity to understand historically the potential consequences of these counting practices. Together they reveal how institutional identities contributed to the making of public health data-- its production, content and interpretation. This data, meant to reveal patterns of disease and improve public health, has paradoxically played a role in concentrating health inequities in the San Joaquin Valley because it has often made invisible the relationships between material deprivation and health or the environment and health. This dissertation does not advocate that we cease to use numbers in science and in policy. Rather, it is meant to recognize that every system of data collection and surveillance, regardless of the institution producing the data, is subjective and is shaped by particular values that have material consequences on populations As a result, the analysis intends to render numbers and their production more transparent and therefore open to critical analysis, and to provoke reflection on how the human elements- history, culture, and experiences --can explain the inequities that data alone can conceal.
  • 2011 Springer
    Jose Russo, editor.
    Epidemiologic basis of the role of environmental endocrine disruptors in breast cancer / Robert A. Hiatt -- Puberty as a window of susceptibility / Frank M. Biro and Mary S. Wolff -- In search of the optimal experimental model / Irma H. Russo and Jose Russo -- Early life exposure to bisphenol A and breast neoplasia / Maricel V. Maffini, Carlos Sonnenschein, and Ana M. Soto -- Endocrine disruptors affect the genomic profile of the rat mammary gland at different developmental stages / Ricardo Lopez de Cicco ... [et al.] -- Proteomic basis for the increased susceptibility of the mammary gland to carcinogenesis after perinatal exposure to bisphenol A / Sarah Jenkins ... [et al.] -- Dioxin as an environmental pollutant and its role in breast cancer / Stephen Safe, Kelcey Walker, and Shu Zhang -- Mammary gland as a sensitive tissue to developmental exposures of perfluorooctanoic acid (PFOA) in the mouse / Sally S. White ... [et al.] -- Atropine : an environmental endocrine disruptor that alters mammary gland development and tumor susceptibility / Jennifer L. Rayner and Suzanne E. Fenton -- Biological impact of radiation exposure on breast cancer development / David H. Nguyen, Irineu Illa Bochaca, and Mary Helen Barcellos-Hoff -- Brain estrogens and metabolism / Yong Xu and Deborah J. Clegg.
  • 2015 Springer
    Mieczyslaw Pokorski, editor.
    The impairment of lung function caused by environmental exposure to pollutants and toxicants is a rising health problem, particularly in highly industrialized parts of the world. The problem is urgently calling for the development of new methodologies to assess both the level of elemental exposure and the effects for quality of health and longevity. This volume provides state-of-the-art information about the recent advances in occupational and non-occupational pollutant-related disorders of the respiratory tract, and the assessment of a threat they pose for the health-span. Heavy traffic-related air pollution, unnoticeable but salient health detriment, is dealt with at length.
    Also available: Print – 2015
  • 2006 Springer
    by Paolo F. Ricci.
  • 2007 Springer
    volume editors, C.P. Kubicek, I.S. Druzhinina.
  • 2007 Ovid
    edited by William N. Rom ; associate editor, Steven B. Markowitz.
    Discipline of environmental and occupational medicine / William N. Rom -- The Role of surveillance in occupational health / Steven B. Markowitz -- The Occupational and environmental history and examination / John E. Parker -- Epidemiology of occupational diseases / Gary M. Marsh -- Occupational biostatistics / Howard E. Rockette -- Impairment, disability, and functional capacity / Alan L. Engelberg and William Greaves -- Molecular biology / John G. Hay -- TP53 tumor suppressor gene / S. Perwez Hussain and Curtis C. Harris -- Biomarkers / Sudhir Srivastava and Karl E. Krueger -- Genetic susceptibility / Chu-Ling Yu and David C. Christiani -- Environmental mutagenesis / C. Stuart Baxter -- Evaluation of occupational exposures and effects on male and female reproduction / Susan Rae Reutman and Grace K. LeMasters -- Particle deposition and pulmonary defense mechanisms / Morton Lippmann and Lung-chi Chen -- Lung immune defenses against environmental agents / Lester Kobzik -- Pulmonary function testing / Stuart M. Garay -- Imaging of pneumoconioses / David A. Lynch -- Molecular mechanisms of particle-induced lung disease / Arnold R. Brody and Gilbert F. Morris -- Analysis of fibrous and nonfibrous particles / Jerrold L. Abraham and Bryan R. Burnett -- Asbestosis, pleural fibrosis, and lung cancer / William N. Rom -- Malignant mesothelioma / Delia Nelson ... [et al.] -- Man-made vitreous fibers, vermiculite, and zeolite / James E. Lockey, Vikas Kapil, and Nancy K. Wiese -- Respiratory disease in coal miners / Michael D. Attfield, Vincent Castranova, and Gregory R. Wagner -- The Health effects of silica exposure / Ahmad S. Jalloul and Daniel E. Banks -- Hypersensitivity pneumonitis / Yvon Cormier and Yves Lacasse -- Inhalation fever / Paul David Blanc -- Occupational and environmental asthma / Stuart M. Brooks, Thomas Truncale, and James McCluskey -- Environment, genes, and immune mechanisms in asthma / Joan Reibman, Linda Rogers, and Maria Elena Fernandez-Beros -- Firefighter's health and health effects of the world trade center collapse / Michael Weiden ... [et al.] -- International byssinosis / Denise Harrison -- Isocyanates exposures and health effects / Carrie Redlich and Dhimiter Bello -- Occupational exposures as a cause of chronic airways disease / John R. Balmes -- Lung Diseases associated with silicates and other dust / Vinicius Antao, Germania Pinheiro, and John E. Parker -- Respiratory tract irritants / Tee Guidotti -- Simple asphyxiants / Marc Wilkenfeld -- Chemical asphyxiants / William S. Beckett -- Agricultural dust-induced lung disease / M. Brian Hartz, Nancy Sprince, and Joel Kline -- Upper airway disorders / Rebecca Bascom and Marina Y. Dolina -- Occupational skin disease / David Cohen and Megan M. Moore -- Toxic peripheral neuropathy / Margit L. Bleecker -- Human behavioral neurotoxicology / W. Kent Anger, Diane S. Rohlman, and Daniel Storzbach -- Occupational heart disease / Kenneth D. Rosenman -- Occupational eye disorders / Jason A. Goldsmith, Norman A. Zabriskie and Randall J. Olson -- Occupational infections / Kevin Dieckhaus -- Terrorism preparedness / Lewis Goldfrank and Howard Greller -- HIV in the workplace / Marty Markowitz ... [et al.] -- The Occupational risk of tuberculosis care / Kent A. Sepkowitz and Tara Palmore -- Hematologic effects of occupational hazards / John H. Ward -- Toxic liver disorders / John D. Groopman and Denise Johnson -- Environmental and occupational causes of toxic injury to the kidneys and urinary tract / Edward T. Zawada, Jr. -- Occupational bladder cancer / Steven B. Markowitz -- Psychiatric syndromes common to the workplace / Robert C. Larsen -- Alcohol and drug abuse in industry / Kent W. Peterson and Donna R. Smith -- Psychological job stress / Joseph J. Hurrell, Jr. -- Multiple chemical sensitivity / Alan M. Ducatman -- Gulf war illness / Howard Kipen and Melissa McDiarmid -- Occupational safety and human factors / Howard Sandler -- Ergonomics and occupational biomechanics / Manny Halpern -- Nonspecific low back pain / Margareta Nordin -- Carpal tunnel syndrome / Owen Kieran -- Toxicogenomics and exposure assessment / Samuel Wilson ... [et al.] -- Occupational and environmental exposure to lead / Alf Fischbein and Howard Hu -- Mercury / Lynn Goldman -- Cadmium / Dominique F. Lison and Violaine Verougstraete -- Arsenic / Toby G. Rossman -- Beryllium disease / Lisa A. Maier, Carol Gunn and Lee S. Newman -- Hard metal disease / Dominique F. Lison -- Chromium compounds / Mitchell D. Cohen and Max Costa -- Nickel compounds / Mitchell D. Cohen, Catherine Klein and Max Costa -- Metal compounds and rare earths / Bruce Fowler -- Organic solvents and fuels / Nancy L. Fiedler and Steven Lerman -- Benzene / Philip J. Landrigan -- Formaldehyde / Dean B. Baker -- Ethylene oxide / Anthony D. LaMontagne, N. Kyle Steenland and Karl T. Kelsey -- Pesticides / Marc B. Schenker, Steven R. Offerman, and Timothy E. Albertson -- Health effects of agent orange, other military herbicides, and dioxins / Jeanne M. Stellman and Steven D. Stellman -- Pentachlorophenol and tetrachlorophenol / Glenys M. Webster, Shona J. Kelly and Kay Teschke -- Polychlorinated biphenyls / Stephen H. Safe -- Trimellitic anhydride and other acid anhydrides / Leslie C. Grammer and Kathleen E. Harris -- Carbon disulfide / Stephen M. Levin and Ruth Lilis -- N Nitrosamines / Stephen S. Hecht -- Polycyclic aromatic hydrocarbons and petroleum industry / Steven D. Stellman and Tee L. Guidotti -- Occupational hazards in the microelectronics industry / Joseph LaDou -- Radiation carcinogenesis / Fred Burns ... [et al.] -- Nonionizing radiation / W. Gregory Lotz -- Occupational exposure to noise / Robert J. McCunney and John Meyer -- Dysbarism / Rafael E. de la Hoz -- High-altitude illnesses / William N. Rom -- Thermal extremes in the work environment / Kathleen A. Delaney and Lewis R. Goldfrank -- Occupational exposure to vibration / Donald E. Wasserman and Jack Wasserman -- Shift work and long work hours / Claire Caruso and Roger R. Rosa -- Sleep disorders and work / Joyce A. Walsleben, Edward B. O'Malley, and David M. Rapoport -- Sick building syndrome and building-related illness / Kathleen Kreiss -- Air pollution : outdoor and indoor sources / George D. Thurston -- Air pollution : epidemiology / Johnathan Samet -- Air pollution : human health studies / Robert B. Devlin and Donald Graff -- Air pollution : toxicological studies / Terry Gordon -- Ozone / Morton Lippmann -- Nitrogen oxides / Richard Schlesinger -- Sulfur dioxide / Mark Frampton and Mark J. Utell -- Particulate matter / Sverre Vedal and Jeffrey H. Sullivan -- Acid rain / Kathleen C. Weathers, Gene E. Likens, and Thomas J. Butler -- Cigarette smoking / Jonathan Samet and Stephen S. Hecht -- Bioaccumulation and toxicities of aromatic hydrocarbon contaminants at different trophic levels of the Hudson River ecosystem / Isaac I. Wirgin -- The Built environment / Howard Frumkin -- Biological and medical implications of global warming / Paul R. Epstein -- Chlorofluorocarbons and destruction of the ozone layer / Mario J. Molina and Luisa T. Molina -- Environmental law and policy / Jeffrey G. Miller -- Clean Air Act / Daniel Greenbaum -- Occupational Safety and Health Administration and the National Institute for Occupational Safety and Health / John Howard -- United States Environmental Protection Agency / Kathleen Callahan ... [et al.] -- Environmental health practice and research at the Centers for Disease Control and Prevention and the Agency for Toxic Substances and Disease Registry / Thomas H. Sinks and Henry Falk -- Risk assessment and economic evaluation / James Hammitt -- Workers' compensation / Nicholas A. Ashford -- International occupational and environmental health / Joseph LaDou -- Children's environmental health research / Frederica Perera and Sheila Viswanathan -- Disparities in environmental and occupational health / George Friedman-Jiménez and Luz Claudio -- Industrial hygiene measurement and control / Beverly S. Cohen -- Respirators / Philip Harber -- The Occupational health service / Peter Rabinowitz and Oyebode Taiwo -- Moral questions of occupational and environmental medicine / Sheldon Samuels -- New frontiers in environmental health research / David A. Schwartz, Brenda K. Weis, and Samuel H. Wilson.
  • 2015 Springer
    Mieczyslaw Pokorski, editor.
    The book presents the latest advances in research into health effects of air pollution, with heavy motor vehicle traffic or cigarette smoke as the exemplar of pollution. The airways are the first-line defense system against pollution. The book focuses on respiratory ailments underlain by inflammation, increased susceptibility to infection, particularly acquired during harsh environmental conditions and exposures to particulate matter or pathogens. The importance of astute analysis of lung function for early diagnosis of disorders is underscored. A knowledge deficit concerning the aerosolized drug delivery through the airways also is addressed. Recent developments and viewpoints in the field of environmental health hazards as well as methodological advances in their assessment are provided. The book will be of interest to pulmonologists, healthcare providers, researchers and clinicians engaged in environment-related respiratory diseases, but also to policy makers concerned with clean ambient air quality.
    Also available: Print – 2015
  • 2015
  • 2007 Springer
    edited by Gerrit W. Heil, Bart Muys and Karin Hansen.
  • 2001 CRCnetBASE
    Thomas M. Pankratz.
  • 2013 Springer
    Randy L. Jirtle, Frederick L. Tyson, editors.
    The capacity of the epigenome to interpret both internal and external stimuli and alter expression programs is a critical component in normal development, aging, and disease pathogenesis. In the past decade, we have witnessed an explosion of unprecedented research on and support for epigenetics, epigenomics, and their interface with human health and disease. In this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, a number of leading investigators in the field of epigenetics discuss patterns of epigenomic modifications in normal cells, and how environmentally-induced changes in them are associated with disease pathogenesis. The authors comprehensively review the epigenetic adaptations that occur in human embryonic stem cells, as well as in differentiating cells and organs such as the brain when exposed to environmental factors, and discuss the legal and ethical implications of such alterations. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic programming.
  • 2013 Springer
    Randy L. Jirtle, Frederick L. Tyson, editors.
    Exposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, cocaine, radiation, tobacco smoke, and xenoestrogens. Particular emphasis is placed on the consequences of environmental exposures during development on epigenetic reprogramming that influences adult disease pathogenesis. Health outcomes associated with these exposures include autoimmune disorders, neurodevelopmental disorders, and cancer. Importantly, dietary supplements and drugs can modify the epigenetic effects induced by these agents, thereby reducing their toxicological impact. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic processes and developmental programming.
  • 2010 Springer
    Deodutta Roy, M. Tevfik Dorak, editors.
    Part 1. General Principles -- Introduction / Deodutta Roy and M. Tevfik Dorak -- Gene-Environment Interactions, Phenotypic Changes, and Human Health / Rosemarie G. Ramos and Kenneth Olden -- Statistics for Testing Gene-Environment Interaction / Momiao Xiong and Xuesen Wu -- Clustering Studies for Identifying the Role of Environmental Factors in Aetiology of Human Cancers / Richard J.Q. McNally -- Discovering Gene-Gene and Gene-Environment Causal Interactions Using Bioinformatics Approaches / Changwon Yoo -- Gene Environment Interactions and Vascular Lesions / Quentin Felty -- Epigenetic Changes in Cancer: Role of Environment / Zdenko Herceg and Paolo Boffetta -- Approaches to Identify Environmental and Epigenomic Components or Covariates of Cancer and Disease Susceptibility / Alok Deoraj and Deodutta Roy -- Part 2. Environment and Specific Types of Cancer -- Gene-Environment Interaction and Susceptibility to Pediatric Brain Tumors / Brian Kunkle, David Sandberg, Prasanna Jayakar, Quentin Felty and Deodutta Roy -- Genetic Polymorphisms Predisposing Individuals to Breast Cancer Via Gene-Environment Interaction / Keun-Young Yoo, Sue K. Park and Aesun Shin -- Environment, Genetic Immunology and Childhood Cancer / Esma Ucisik-Akkaya and M. Tevfik Dorak -- Exposure to Environmental Mutagens: APC and Colorectal Carcinogenesis / Aruna S. Jaiswal, Melissa L. Armas, Shahnjayla K. Connors, Harekrushna Panda and Satya Narayan -- Gene-Environmental Interactions and Susceptibility to Liver Cancer / John B. Colerangle -- Genetic Epidemiology of Mismatch Repair Deficiency in Ovarian Cancer / Tuya Pal, Jenny Permuth Wey and Thomas A. Sellers -- Part 3. Case Studies -- Betel Nut and Susceptibility to Cancer / Rajesh N. Sharan and Yashmin Choudhury -- Birth Weight and Cancer Associations / Nadia Barahmani and M. Fatih Okcu -- Iron Excess and Cancer / Charronne F. Davis and M. Tevfik Dorak.
  • 2007 Karger
    volume editor, E. Tur.
    Also available: Print – 2007
  • 2007 Springer Protocols
    edited by C. Cristofre Martin.
    Preface -- Contributors -- Pt. 1. Gene expression profiling -- 1. High-throughput whole mount in situ hybridization of zebrafish embryos for analysis of tissue-specific gene expression changes after environmental perturbation / Louise E. Coverdale, Lindsay E. Burton, and C. Cristofre Martin -- 2. Fluorescent RNA arbitrarily primed polymerase chain reaction / Doug Crump ... [et al.] -- 3. Isolation of O₃-response genes from Arabidopsis thaliana using cDNA macroarray / Masanori Tamaoki -- 4. Use of cDNA macroarrays and gene profiling for detection of effects of environmental toxicants / Jason L. Blum ... [et al.] -- 5. Constructing and screening a cDNA library / Kevin Larade and Kenneth B. Storey -- 6. Comparative molecular physiological genomics / Sean F. Eddy and Kenneth B. Storey -- 7. Proteomic analysis of neuroendocrine peptidergic system disruption using the AtT20 pituitary cell line as a model / Fumin Dong ... [et al.] -- 8. Proteomics-based method for risk assessment of peroxisome proliferating pollutants in the marine environment / Susana Cristobal -- 9. Environmental metabolomics using ¹H-NMR spectroscopy / Mark R. Viant -- Pt. 2. Detection of whole genome mutation -- 10. Restriction landmark genome scanning for the detection of mutations / Jun-ichi Asakawa -- 11. Use of the comet assay in environmental toxicology / Loren D. Knopper and James P. McNamee -- 12. The micronucleus assay determination of chromosomal level DNA damage / Michael Fenech -- 13. Fluorescence in situ hybridization for the detection of chromosome aberrations and aneuploidy induced by environmental toxicants / Francesca Pacchierotti and Antonella Sgura -- 14. Laboratory methods for the detection of chromosomal structural aberrations in human and mouse sperm by fluorescence in situ hybridization / Francesco Marchetti, Debby Cabreros, and Andrew J. Wyrobek -- Pt. 3. Determination of species diversity -- 15. Assembling DNA barcodes / Jeremy R. deWaard ... [et al.] -- 16. Application of suppressive subtractive hybridization to uncover the metagenomic diversity of environmental samples / Elizabeth A. Galbraith, Dionysios A. Antonopoulos, and Bryan A. White -- 17. 16S rRNA targeted DGGE fingerprinting of microbial communities / Vesela A. Tzeneva ... [et al.] -- 18. An emulsion polymerase chain reaction-based method for molecular haplotyping / James G. Wetmur and Jia Chen -- Index.
  • v. 1-, 1976- WHO
  • 2009/2010
    Jeffrey J. Margolis.
    Status: Not Checked OutLane Catalog Record
  • 2009 CRCnetBASE
    editors, Eddie N. Laboy-Nieves, Fred C. Schaffner, Ahmad H. Abdelhadi, Mattheus F.A. Goosen.
    Globalization and sustainable growth -- Bioethics, environmental pollution and poverty -- Organizational performance and sustainability -- Environmental management and human progress -- Renewable energy. Ecosystems and environmental health -- Materials recycling and water treatment.
  • 2005 ScienceDirect
    edited by Jared R. Leadbetter.
    Cultivation -- Physiological ecology -- Nucleic acid techniques.
    Also available: Print – 2005
  • 2014 Springer Protocols
    edited by Ian T. Paulsen, Andrew J. Holmes.
    Methods for isolation and cultivation of filamentous fungi / Helena Nevalainen, Liisa Kautto, and Junior Te'o -- Rapid extraction of PCR-competent DNA from recalcitrant environmental samples / Michael R. Gillings -- Quantitative PCR for detection of mRNA and gDNA in environmental isolates / Anthony J. Brzoska and Karl A. Hassan -- Analysis of community dynamics in environmental samples using denaturing gradient gel electrophoresis / Claire L. Thompson -- Terminal restriction fragment length polymorphism (T-RFLP) profiling of bacterial 16S rRNA genes / Catherine A. Osborne -- Profiling the diversity of microbial communities with single-strand conformation polymorphism (SSCP) / Achim Schmalenberger and Christoph C. Tebbe -- Human fecal source identification with real-time quantitative PCR / Orin C. Shanks ... [and 4 others] -- Next generation barcode tagged sequencing for monitoring microbial community dynamics / Katy Breakwell, Sasha G. Tetu, and Liam D.H. Elbourne -- Analysis of methanotroph community structure using a pmoA-based microarray / Guy C.J. Abell ... [and 3 others] -- Biolog Phenotype MicroArrays for phenotypic characterization of microbial cells / Amanda M. Mackie ... [and 3 others] -- Visualization of metabolic properties of bacterial cells using nanoscale secondary ion mass spectrometry (NanoSIMS) / Yi Vee Chew, Andrew J. Holmes, and John B. Cliff -- Single-cell Raman sorting / Mengqiu Li ... [and 3 others] -- Bacterial whole-cell biosensors for the detection of contaminants in water and soils / Yun Wang ... [and 3 others] -- Stable isotope probing to study functional components of complex microbial ecosystems / Sophie Mazard and Hendrik Schäfer -- Metagenomics using next-generation sequencing / Lauren Bragg and Gene W. Tyson -- Targeted genomics of flow cytometrically sorted cultured and uncultured microbial groups / Sophie Mazard ... [and 4 others] -- Quantitative microbial metatranscriptomics / Scott Gifford, Brandon Satinsky, and Mary Ann Moran -- Quantitative metaproteomics : functional insights into microbial communities / Chongle Pan and Jillian F. Banfield.
  • 2007 CRCnetBASE
    edited by Anne Marie Dixon.
  • 2013 CRCnetBASE
    editors, Stanley A. Morain & Amelia M. Budge.
    "Satellite imagery and data are widely used in public health surveillance to provide early warning of disease outbreaks and for averting pandemics. Convergence of these technologies began in the 1970s and has gained wide acceptance in the 21st Century. This book is written jointly by experts in both the health and Earth-science technologies. Each chapter is accompanied by an extensive list of citations to provide background and validation of the current state-of-the-art for a variety of high-interest human diseases and associated health and well-being issues. The importance of day-to-day weather patterns, the impacts of severe weather events and longer-term climate cycles form the basis for developing information systems that meet goals and expectations of national and international health monitoring bodies"--Provided by publisher.
  • 2011
    Chirag Jagdish Patel.
    Common diseases arise out of combination of both genetic and environmental influences. Advances in genomic technology have enabled investigators to create hypotheses regarding the contribution of genetic factors at a breathtaking pace. However, the assessment of multiple and specific environmental factors--and their interactions with the genome-- has not. We lack high-throughput analytic methodologies to comprehensively and systematically associate multiple physical and specific environmental factors, or the "envirome", to disease and human health. We claim that the creation of hypotheses regarding the environmental contribution to disease is practicable through high-throughput analytic methods that have been well established in genomics. In the following dissertation, we develop and apply methods to systematically and comprehensively associate specific factors of the envirome with disease states, prioritizing factors for in-depth future study. The current disciplines of studying the environmental determinants of health include toxicology and epidemiology, which operate on molecular and population scales, respectively. This dissertation proposes approaches in both of these disciplines. For example, we have developed a framework to conduct the first "Environment-wide Association Study" (EWAS), systematically associating environmental factors to disease on a population scale. We have applied this framework to investigate type 2 diabetes and heart disease on cohorts that are representative United States population, finding novel and robust associations in diverse and independent cohorts. Given the lack of explained risk resulting from current day genome-wide studies, the time is ripe to usher in a more comprehensive study of the environment, or "enviromics", toward better understanding of multifactorial diseases and their prevention.
  • 2008
    [edited by] Sharon W. Weiss, John R. Goldblum.
    Status: Not Checked OutLane Catalog Record
  • 2013 ClinicalKey
    John R. Goldblum, Andrew L. Folpe, Sharon W. Weiss.
    Enzinger and Weiss's Soft Tissue Tumors is a medical reference on the diagnosis of tumors of the skeletal muscles, connective tissue, fat, and related structures. Microscopic findings are correlated with the latest developments in molecular biology, cytogenetics, and immunohistochemistry, providing you with a comprehensive and integrated approach to the evaluation of soft tissue specimens. Apply the latest advances in surgical pathology thanks to major updates on recently identified pathological entities such as soft tissue angiofibroma and CIC-related sarcomas; coverage of the newest molecular diagnostic techniques and immunohistochemical and molecular genetic features of soft tissue tumors; new chapters on GIST and soft tissue tumors showing melanocytic differentiation; and more. Effortlessly find the information you need with a chapter organization based on the newest surgical pathology concepts and classifications of soft tissue tumors.
    Also available: Print – 2014
  • 2013 Springer
    Soundar Divakar.
    Transformations using enzymes have been extensively investigated in the last two decades and the results promise great potential for this growing field, especially in the area of synthetic organic chemistry mainly due to of its many advantages. Accordingly, this book has attempted to bring out the advantages of using enzymes involving complex underivatized and unprotected substrates in non-polar media under homogenous and heterogeneous reaction conditions. Merits and demerits of using enzymes in terms of yields and selectivity/specificity are presented without any prejudice. Almost all the reactions dealt with are from the author's laboratory comprising diverse substrates, and the catalysis involves two important hydrolyzing enzymes, extensively examined for the reverse reactions. Thus, esterification involving lipses and glycosylation involving glycosidases were investigated with respect to various strategies like optimization of reaction conditions, response surface methodology and kinetics, carrying out reactions under solvent, non-solvent and super critical carbon dioxide conditions. In short, the work presented is to ensure the comprehension of the problems faced by the researchers in this area so as to work out further efficient strategies for carrying out enzymatic transformations in the laboratory successfully with better yields and specificity.
  • 2010 Springer
    K. Sandy Pang, A. David Rodrigues, Raimund M. Peter.
  • 2013 Springer Protocols
    edited by James C. Samuelson.
    1. Tripartite fusion system for the selection of protein variants with increased stability in vivo / Linda Foit and James C.A. Bardwell -- 2. Determining enzyme kinetics via isothermal titration calorimetry / Neil A. Demarse, Marie C. Killian, Lee D. Hansen and Colette F. Quinn -- 3. GFP reporter screens for the engineering of amino acid degrading enzymes from libraries expressed in bacteria / Olga Paley, Giulia Agnello, Jason Cantor, Tae Hyun Yoo, George Georgiou and Everett Stone -- 4. Flow cytometric assays for interrogating LAGLIDADG homing endonuclease DNA-binding and cleavage properties / Sarah K. Baxter, Abigail R. Lambert, Andrew M. Scharenberg and Jordan Jarjour -- 5. TAL effector nuclease (TALEN) engineering / Ting Li and Bing Yang -- 6. In vitro evolution of enzymes / Misha V. Golynskiy, John C. Haugner III, Aleardo Morelli, Dana Morrone and Burckhard Seeling -- 7. Residue-specific incorporation of unnatural amino acids into proteins in vitro and in vivo / Amrita Singh-Blom, Randall A. Hughes, and Andrew D. Ellington -- 8. Reconstructing evolutionary adaptive paths for protein engineering / Megan F. Cole, Vanessa E. Cox, Kelsey L. Gratton, and Eric A. Gaucher -- 9. Oligonucleotide recombination enabled site-specific mutagenesis in bacteria / Bryan M. Swingle -- 10. FX cloning : a versatile high-throughput cloning system for characterization of enzyme variants / Eric R. Geertsma -- 11. Use of Sulfolobus solfataricus PCNA subunit proteins to direct the assembly of multimeric enzyme complexes / Hidehiko Hirakawa and Teruyuki Nagamune -- 12. Gene synthesis by assembly of deoxyuridine-containing oligonucleotides / Romualdas Vaisvila and Jurate Bitinaite -- 13. Protein engineering : single or multiple site-directed mutagenesis / Pei-Chung Hsieh and Romualdas Vaisvila -- 14. Gene assembly and combinatorial libraries in S. cerevisiae via reiterative recombination / Nili Ostrov, Laura M. Wingler, and Virginia W. Cornish -- 15. Promiscuity-based enzyme selection for rational directed evolution experiments / Sandeep Chakraborty, Renu Minda, Lipika Salaye, Abhaya M. Dandekar, Swapan K. Bhattacharjee and Basuthkar J. Rao -- 16. Rational protein sequence diversification by multi-codon scanning mutagenesis / Jia Liu and T. Ashton Cropp -- 17. Screening libraries for improved solubility : using E. coli dihydrofolate reductase as a reporter / Jian-Wei Liu and David L. Ollis -- 18. In vitro directed evolution of enzymes expressed by E. coli in microtiter plates / Bradley J. Stevenson, Sylvia H.-C. Yip, and David L. Ollis.
  • 2010 ScienceDirect
    Daniel L. Purich.
    Chapter 1. An Introduction to Enzyme Science -- Chapter 2. Active Sites and their Chemical Properties -- Chapter 3. Fundamentals of Chemical Kinetics -- Chapter 4. Practical Aspects of Measuring Initial Rates and Reaction Parameters -- Chapter 5. Initial-Rate Kinetics of One-Substrate Enzyme-Catalyzed Reactions -- Chapter 6. Initial-Rate Kinetics of Multi-Substrate Enzyme-Catalyzed Reactions -- Chapter 7. Factors Influencing Enzyme Activity -- Chapter 8. Kinetic Behavior of Enzyme Inhibitors -- Chapter 9. Isotopic Probes of Biological Catalysis -- Chapter 10. Probing Fast Enzyme Processes -- Chapter 11. Regulatory Behavior of Enzymes -- Chapter 12. Single-Molecule Enzyme Kinetics -- Chapter 13. Mechanoenzymes: Catalysis, Force Generation and Kinetics.
  • 2011 Wiley
    Robert A. Alberty.
    Also available: Print – v. 53, 2011.
  • ScienceDirect
    edited by Daniel L. Purich.
    Also available: Print – 1982
  • ScienceDirect
    edited by Daniel L. Purich.
    Also available: Print – 1995
  • 2002 ScienceDirect
    edited by Daniel L. Purich.
    Also available: Print – 2002

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