BookEngin Oral, editor.
Summary: Although endometriosis and adenomyosis are often assessed under the same umbrella, the epidemiology, clinical manifestations and management strategies of endometriosis and adenomyosis occur differently during the life cycle of a woman. Endometriosis can be diagnosed at many points across the lifespan, including adolescence and the climacterium, as well as pregnancy. Being associated with potential adverse health effects, different clinical presentations requiring different therapeutic approaches render it imperative to tailor management strategies for each period of the lifespan: in utero and early life, puberty and adolescence, reproductive years, pregnancy, late reproductive age, and the menopause. This book provides comprehensive insight into the general aspects, diagnosis and treatment modalities of endometriosis and adenomyosis in all stages of a woman's life - a unique element of its approach. Thematic sections discuss the basics of diagnosis and management of both endometriosis and adenomyosis from birth through menopause, including aspects of fertility preservation, sexual dysfunction, psychological considerations and prevention. The current pharmaceutical approaches and efficacy are presented, including progestins, aromatase inhibitors and GnRH agonists and antagonists. The final section provides current practice guidelines for the management of both conditions as well as an investigation into future research and clinical strategies. Taking a truly global perspective, Endometriosis and Adenomyosis will be a valuable resource for reproductive endocrinologists, infertility specialists and obstetricians and gynecologists worldwide.
Contents:
Part I. Endometriosis: An Overview
Endometriosis in Human History
Global Epidemiologic Data on Endometriosis
Presumptive Causes of Endometriosis across the Lifespan
Pathogenesis of Endometriosis: Retrograde Menstruation and Metaplasia, Inflammation, Autoimmunity, Genetics
Classification and Clinical Staging of Endometriosis
Diagnostic Modalities: Imaging and Markers
Multidisciplinary Aspects of Chronic Pain without Endometriosis
Part II. Endometriosis across the Lifespan
Endometriosis In Utero and Early Life
Endometriosis in Adolescence
Endometriosis in the Reproductive Years: Fertility and Pain
Endometriosis in Peri- and Postmenopausal Years
Pregnancy and Obstetric Outcomes
Part III. Miscellaneous Clinical Presentations and Management of Endometriosis
Recurrent Endometriosis
A Rare Entity of Extra Pelvic Endometriosis: Scar, Diaphragmatic, Pulmonary Involvement
Fertility Preservation for Endometriosis
Malignancy Risks Associated with Endometriosis
Psychological Considerations in Endometriosis
Sexual Dysfunction and Endometriosis
Nutritional Interventions, Complementary and Alternative Medicine for Endometriosis
Prevention of Endometriosis: Is It Possible?- How to Establish a "Center of Excellence" for Endometriosis
Cost Estimates Associated with Diagnosis and Treatment of Endometriosis
Part IV. Adenomyosis: An Overview
What Is Adenomyosis?- Adenomyosis in Medicine
Insights into Adenomyosis Development
Classification and Staging of Adenomyosis
Non-invasive Diagnosis of Adenomyosis: Ultrasonography and MRI
Part V: Adenomyosis across the Lifespan
Adenomyosis in Adolescence
Adenomyosis in the Reproductive Years: Abnormal Uterine Bleeding, Pain, Fertility
Pregnancy and Obstetric Outcomes in Adenomyosis
Does Adenomyosis Increase Cancer Risk?- Part VI. Clinical Pharmaceutical Features of Drugs Used in Endometriosis and Adenomyosis Treatment
Hormonal Therapy: Oral Contraceptives, Progestins, Danazol, Aromatase Inhibitors
GnRH Agonists and Antagonists
Part VII. Guidelines and Future Prospects for Endometriosis and Adenomyosis
Recent Guidelines on Endometriosis and Adenomyosis
The Future of Endometriosis and Adenomyosis Research.