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  • YAC protocols. 2nd ed. 2006
    Springer Protocols
    Markers, selection, and media in yeast artificial chromosomes cloning / David Markie -- Construction of yeast artificial chromosome libraries from pathogens and nonmodel organisms / Cecilia P. Sanchez and Michael Lanzer -- Analysis and screening of yeast artificial chromosome libraries by filter hybridization / Cecilia P. Sanchez and Michael Lanzer -- Analysis of Yeast Artificial Chromosome DNA by restriction digestion, southern blotting nucleic acid hybridization and polymerase chain reaction / Sylvia Vasiliou and John Peter Quinn -- Postgenomic bioinformatic analysis of yeast artificial chromosome sequence / Kerry Miller, Scott Davidson, and Alasdair MacKenzie -- Transformation of yeast using bioactive beads with surface-immobilized yeast artificial chromosomes / Shigeki Kawakami ... [et al.] -- Modification and amplification of yeast artificial chromosomes / Sanbing Shen, Anthony Harmar, and Nick Hastie -- Modifying yeast artificial chromosomes to generate Cre/LoxP and FLP/FRT site-specific deletions and inversions / Gabriela G. Loots -- Selective isolation of large chromosomal regions by transformation-associated recombination cloning for structural and functional analysis of mammalian genomes / Natalay Kouprina, Vladimir N. Noskov, and Vladimir Larionov -- A polymerase chain reaction-mediated yeast artificial chromosome-splitting technology for generating targeted yeast artificial chromosomes subclones / Yeon-Hee Kim ... [et al.] -- Genomic reconstruction by serial mitotic recombination of yeast artificial chromosomes / David Markie, Emma Jones, and Jiannis Ragoussis -- Targeting vector construction by yeast artificial chromosome modification / Peter J. Murray -- Production of yeast artificial chromosomes transgenic mice by pronuclear injection of one-cell embryos / Alasdair MacKenzie -- Generation of yeast artificial chromosomes transgenic mice by intracytoplasmic sperm injection / Pedro N. Moreira ... [et al.] -- Establishment of cell lines that exhibit correct ontogenic stage-specific gene expression profiles from tissues of yeast artificial chromosome transgenic mice using chemically induced growth signals / C. Anthony Blau and Kenneth R. Peterson -- Application of yeast artificial chromosomes in fluorescence in situ hybridization / Thomas Liehr -- Contribution of yeast artificial chromosome-based physical maps to the final assembly of the trypanosoma cruzi genome / Marcia R.M. Santos ... [et al.].
  • "The Yale Swallow Protocol is an evidence-based protocol that is the only screening instrument that both identifies aspiration risk and, when passed, is able to recommend specific oral diets without the need for further instrumental dysphagia testing. Based upon research by Drs. Steven B. Leder and Debra M. Suiter, an easily administered, reliable, and validated swallow screening protocol was developed and can be used by speech-language pathologists, nurses, otolaryngologists, oncologists, neurologists, intensivists, and physicians assistants. In addition, the protocol can be used in a variety of environments, including acute care, rehabilitation, and nursing homes. The Yale Swallow Protocol meets all of the criteria necessary for a successful screening test, including being simple to administer, cross-disciplinary, cost effective, acceptable to patients, and able to identify the target attribute by giving a positive finding when aspiration risk is present and a negative finding when aspiration risk is absent. Additionally, early and accurate identification of aspiration risk can significantly reduce health-care costs associated with recognized prandial aspiration."--Publisher's website.
  • Portable, practical, and entirely clinical, this affordable guide to assessment and management of the entire range of gastroenterological complaints and conditions is ideally suited for use by GI fellows and specialists. The book is divided into two parts: symptom-focused and disease-focused. Features include key practice points, essentials of diagnosis, potential pitfalls, key web links, society guideline comparisons, case studies, and multiple choice questions. When you need answers in a hurry, turn to the most trusted name in gastroenterology: Yamada.
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  • From DNA replication to genome instability in schizosaccharomyces pombe: pathways to cancer / Julie M. Bailis and Susan L. Forsburg -- Dissecting layers of mitotic regulation essential for maintaining genomic stability / Jeffiner S. Searle and Yolanda Sanchez -- Yeast as a tool in cancer research: nuclear trafficking / Anita H. Corbett and Adam C. Berger -- Studies of protein farnesylation in yeast / Nitika Thaper and Fuyuhiko Tamanoi -- From bread to bedside: what budding yeast has taught us about the immortalization of cancer cells / Soma S.R. Banik and Christopher M. Counter -- Hsp90 co-chaperones in saccharomyces cerevisiae / Marija Tesiccc and Richard F. Gaber -- Yeast as a model system for studying cell cycle checkpoints / Carmela Palermo and Nancy C. Walworth -- Metabolism and function of sphingolipids in saccharomyces cerevisiae: relevance to cancer research / L. Ashley Cowart, Yusuf A. Hannun, and Lina M. Obeid -- Exploring and restoring the p53 pathway using the p53 dissociator assay in yeast / Rainer K. Brachmann -- Functional analysis of the Human p53 tumor suppressor and its mutants using yeast / Alberto Inga, Francesca Storici and Michael A. Resnick -- ABC transporters in yeast - drug resistance and stress response in a nutshell / Karl Kuchler and Christoph Schüller -- The FHCRC/NCI yeast anticancer drug screen / Susan L. Holbeck and Julian Simon -- Yeast as a model to study the immunosuppressive and chemotherapeutic drug rapamycin / John R. Rohde, Sara A. Zurita-Martinez, and Maria E. Cardenas -- Use of yeast as a model of system for identifying and studying anti-cancer drugs / Jun O. Liu and Julian A. Simon -- Genetic analysis of cisplatin resistance in yeast and mammals / Seiko Ishida and Ira Herskowitz -- Using yeast tools to dissect the action of anti-cancer drugs: mechanisms of enzyme inhibition and cell killing: agents targeting DNA topoisomerases / Anna Rogojina, ... [et al].
  • Global estimation of mRNA stability in yeast / Julia Marin-Navarro [and others] -- Genomic-wide methods to evaluate transcription rates in yeast / Jose Garcia-Martinez, Vicent Pelechano, and Jose E. Perez-Ortin -- Construction of cis-regulatory input functions of yeast promoters / Prasuna Ratna and Attila Becskei -- Luminescence as a continuous real-time reporter of promoter activity in yeast undergoing respiratory oscillations or cell division rhythms / J. Brian Robertson and Carl Hirschie Johnson -- Linearizer gene circuits with negative feedback regulation / Dmitry Nevozhay, Rhys M. Adams, and Gabor Balazsi -- Measuring in vivo signaling kinetics in a mitogen-activated kinase pathway using dynamic input stimulation / Megan N. McClean, Pascal Hersen, and Sharad Ramanathan -- Stochastic analysis of gene expression / Xiu-Deng Zheng and Yi Tao -- Studying adaptation and homeostatic behaviors of kinetic networks by using MATLAB / Tormod Drengstig, Thomas Kjosmoen, and Peter Ruoff -- Biochemical systems analysis of signaling pathways to understand fungal pathogenicity / Jacqueline Garcia [and others] -- Clustering change patterns using fourier transformation with time-course gene expression data / Jaehee Kim -- Finding modulators of stochasticity levels by quantitative genetics / Steffen Fehrmann and Gael Yvert -- Functional mapping of expression quantitative trait loci that regulate oscillatory gene expression / Arthur Berg [and others] -- Evolutionary aspects of a genetic network : studying the lactose/galactose regulon of Kluyveromyces lactis / Alexander Anders and Karin D. Breunig -- Analysis of subtelomeric silencing in Candida glabrata / Alejandro Juarez-Reyes, Alejandro De Las Penas, and Irene Castano -- Morphological and molecular genetic analysis of epigenetic switching of the human fungal pathogen Candida albicans / Denes Hnisz, Michael Tscherner, and Karl Kuchler -- Quantitation of cellular components in Cryptococcus neoformans for system biology analysis / Arpita Singh, Asfia Qureshi, and Maurizio Del Poeta.
  • Yeast protocols. 2nd ed. 2005
    Springer Protocols
    Basic investigations in saccharomyces cerevisiae / Brendan P.G. Curran and Virginia Bugeja -- Isolation of nucleic acids / Michelle Hanna and Wei Xiao -- Purification of yeast peroxisomes / Ben Distal and Astrid Kragt -- Isolation of yeast plasma membranes / Barry Panaretou and Peter Piper -- Isolation of yeast mitochondria / Chris Meisinger, Nikolaus Pfanner, and Kaye N. Truscott -- Extraction of yeast lipids / Roger Schneiter and Günther Daum -- Two-dimensional gel electrophoresis of total yeast proteins / Hélian Boucherie and Christelle Monribot-Espagne -- Pulsed field gel electrophoresis of budding yeast chromosomes / Laura Maringele and David Lydall -- Analysis of yeast lipids / Roger Schneiter and Günther Daum -- Yeast fluorescence microscopy / Jirí Hasek -- Intracellular expression of recombinant antibody fluorescent protein fusions for localization of target antigens in schizosaccharomyces pombe / Michelle A. Alting-Mees ... [et al.] -- Yeast transformed by the LiAc/SS carrier DNA/PEG method / R. Daniel Gietz and Robin A. Woods -- Mutagenesis / Leslie Barbour, Michelle Hanna, and Wei Xiao -- Gene disruption in the budding yeast saccharomyces cerevisiae / Johannes H. Hegemann, Ulrich Güldener, and Gabriele J. Köhler -- Inducible degron and its application to creating conditional mutants / R. Jürgen Dohmen -- Synthetic lethal screen / Leslie Barbour and Wei Xiao -- Synthetic genetic array analysis in saccharomyces cerevisiae / Amy Hin Yan Tong and Charles Boone -- Two-dimensional agarose gel analysis of DNA replication intermediates / Alain T. Dandjinou ... [et al.] -- Chromatin assembly in a crude fraction from yeast cells / Karen M. Robinson and Michael C. Schultz -- Chromatin immunoprecipitation to study protein/DNA interactions in budding yeast / Elena Ezhkova and William P. Tansey -- Isolation of yeast nuclei and micrococcal nuclease mapping of nucleosome positioning / Zhengjian Zhang and Joseph C. Reese -- Study of transcriptional regulation using a reporter gene assay / Yu Fu and Wei Xiao -- Assessing telomeric phenotypes / Catherine LeBel ... [et al.] -- Controlled expression of recombinant genes and preparation of cell-free extracts in yeast / Zhigang Wang -- Production of heterologous proteins in yeast with the aid of the Hsp150 Carrier / Marja Makarow ... [et al.] -- Yeast two-hybrid system screening / R. Daniel Gietz -- Import of precursor proteins into isolated yeast mitochondria / Nils Wiedemann, Nikolaus Pfanner, and Peter Rehling.
  • Fully revised, updated and offered in a new two-volume format, The Yeasts: A Taxonomic Study, 5th Edition remains the most comprehensive presentation of yeast taxonomy and systematics available. Nearly 1500 species of ascomycete and basidiomycete yeasts are included, each description offering not only standard morphological and physiological characters, but also information on systematics, habitat, ecology, agricultural and biotechnological applications and clinical importance. Extensive introductory chapters discuss clinical aspects of yeasts, their role in biotechnology, food and beverage spoilage, agriculture and ecology, while other chapters include methodology for isolation of species from various habitats, phenotypic characterization, chemotaxonomy, gene sequence analysis and phylogenetics, including whole genome analysis. Additionally, easy-to-understand trees illustrate the phylogenetic placement of each species in its assigned genus as they have been determined from gene sequence analysis. This essential work, prepared by the leading experts in the field, is the most definitive treatment of taxonomy and systematics of yeasts on the market, and a necessary reference for any bookshelf or workbench. High quality photomicrographs and line drawings enhance world-class content Detailed trees clearly illustrate phylogenetic placement of each species in its assigned genus Discussion of clinical aspects of yeasts, including their role in biotechnology, agriculture and ecology help contextualize content for a wide range of researchers.
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    Philadelphia: the great plague of 1793 -- New Orleans: gateway to death -- Memphis almost disappears -- Mississippi devastated by yellow jack -- Spanish-American War: finding the real enemy -- Weapons of mass destruction -- Global warming casts ominous shadow -- The Disease that won't go away.
  • Yen & Jaffe's Reproductive Endocrinology helps you successfully diagnose and manage the spectrum of female and male reproductive system diseases, from impaired fertility, infertility, and recurrent pregnancy loss through problems of sexual development, puberty, menstrual disturbances, fibroids, endometriosis, and reproductive aging. This trusted endocrinology reference book is ideal for fellows preparing for the boards, endocrinologists preparing for recertification, or as a quick reference when making daily diagnostic and therapeutic decisions. It is just the resource you need to offer your patients the best possible reproductive care. Get unmatched guidance you can trust, such as fresh insights into today's field and future advances, through the knowledge gleaned from worldwide fertility experts in reproductive medicine.Further your study of Reproductive Endocrinology with a list of suggested readings at the end of each chapter.Conveniently access the fully searchable text and view all of the images online at Expert Consult.
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  • This book attempts to bridge the considerable gaps that exist between spiritual philosophies and evidence-based medicine and between the psychotherapeutic models of the East and the West. Based on the insights of both the ancient wisdom and modern medicine, this book presents Yogic science not just as a set of physical exercises or religious rituals but as theories about the mind that have bio-psycho-social implications in relation to health and illness. Drawing on his years of monastic training and his extensive experiential, clinical, and research knowledge on the utility of Yoga meditation in standardized and evidence-based medicine protocols, the author describes symptom-specific clinical applications of Yogic/meditative techniques using standardized protocols for the various psychiatric and psychosomatic conditions. In addition, he explains the value of these techniques in reducing stress and improving quality of life in healthy populations. Dr. Pradhan names the proposed integrative model of psychotherapy Yoga and Mindfulness Based Cognitive Therapy (Y-MBCT). Unlike other models, Y-MBCT uses Yoga in its entirety (all eight limbs, including meditation) rather than piecemeal. The standardized and evidence-based format of Yoga meditation described in this book will help all aspiring Yoga practitioners and will hopefully also provide the impetus for multicenter research studies on the value of this ancient wisdom.
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    The Deep South has seen a 36 percent increase in AIDS cases while the rest of the nation has seen a 2 percent decline. Many of the underlying reasons for the disease's continued spread in the region--ignorance about HIV, reluctance to get tested, non-adherence to treatment protocols, resistance to behavioral changes--remain unaddressed by policymakers. In this extensively revised second edition, Kathryn Whettan and Brian Wells Pence present a rich discussion of twenty-five ethnographic life stories of people living with HIV in the South. Most importantly, they incorporate research from their recent quantitative study, "Coping with HIV/AIDS in the Southeast" (CHASE), which includes 611 HIV-positive patients from North Carolina, South Carolina, Georgia, Alabama, and Louisiana. This new edition continues to bring the participant's voices to life while highlighting how the CHASE study confirmed many of the themes that originally emerged from the life histories. This is the first cohesive compilation of up-to-date evidence on the unique and difficult aspects of living with HIV in the Deep South.
  • V. 1: -- Historical overview of neurosurgery -- Surgical anatomy of the brain -- Molecular biology primer for neurosurgeons -- Neuroembryology -- Stem cell biology in the central nervous system -- Neurons and neuroglia -- Cellular mechanisms of brain energy metabolism -- Blood-brain barrier -- Cerebral edema -- Physiology of the cerebrospinal fluid and intracranial pressure -- Neurosurgical epidemiology and outcomes assessment -- Altered consciousness -- Neuroophthalmology -- Neurotology -- Neurourology -- Neuropsychological testing -- Computed tomography and magnetic resonance imaging of the brain -- Radiology of the spine -- Physiologic evaluation of the brain with magnetic resonance imaging -- Molecular imaging of the brain with positron emission tomography -- Neuroanesthesia: preoperative evaluation -- Avoidance of complications in neurosurgery -- Intracranial pressure monitoring -- Principles of neurocritical care -- Surgical planning: overview -- Positioning for cranial surgery -- Patient positioning for spinal surgery -- Positioning in peripheral nerve surgery -- Incisions and closures -- Advantages and limitations of cranial endoscopy -- Thorascopic spine surgery -- Cranioplasty -- Production and flow of cerebrospinal fluid -- Clinical evaluation of adult hydrocephalus -- Shunting -- Adult hydrocephalus: the role of endoscopic third ventriculostomy -- Pathophysiology of subdural hematomas -- Medical and surgical management of chronic subdural hematomas -- Basic science of central nervous system infections -- Postoperative infections of the head and brain -- Postoperative infections of the spine -- The use and misuse of antibiotics in neurosurgery -- Brain abscess -- Meningitis and encephalitis -- Acquired immune deficiency syndrome -- Parasitic infections -- Surgical risk of transmittable diseases -- Epilepsy surgery overview -- Electrophysiologic properties of the mammalian central nervous system -- Animal models of epilepsy -- Malformations of cortical development -- Diagnosis and classification of seizures and epilepsy -- Antiepileptic medications: principles of clinical use -- Continuous electroencephalography in neurological-neurosurgical intensive care: applications and value -- Neuroradiologic evaluation for epilepsy surgery -- Evaluation of patients for epilepsy surgery -- Motor, sensory, and language mapping and monitoring for cortical resections -- Auditory language mapping -- Investigation of human cognition in epilepsy surgery patients -- Intracranial monitoring -- Surgery of extratemporal lobe epilepsy -- Standard temporal lobectomy -- Selective amygdalohippocampectomy -- Tailored resections for epilepsy -- Topectomy and multiple subpial transection -- Hemispheric dissconnection procedures -- Vagus nerve stimulation for intractable epilepsy -- Radiosurgical treatment of epilepsy -- Deep brain stimulation for epilepsy -- Epilepsy surgery: outcome and complications -- Introduction -- Anatomy and synaptic connectivity of the basal ganglia -- Rationale for surgical interventions in movement disorders -- Neuropathology of movement disorders -- Clincial overview of movement disorders -- Patient selection criteria for deep brain stimulation in movement disorders -- Functional imaging in movement disorders -- Surgical management of tremor -- Pallidal interventions for Parkinson's disease -- Subthalamic deep brain stimulation for parkinson's disease -- Subthalamotomy in parkinson's disease: indications and outcome -- Deep brain stimulation for dystonia -- Deep brain stimulation: mechanisms of action -- Emerging and experimental neurosurgical treatments for parkinson's disease -- Seletive peripheral denervation for cervical dystonia -- A history of psychosurgery -- Surgery for tourette's syndrome -- Surgery for obsessive-compulsive disorder -- Surgical treatment of major depression -- Ablative surgery for spasticity -- Management of spasticity by central nervous system infusion techniques -- Treatment of intractable vertigo -- Treatment applications of cortical stimulation -- Neuroprosthestics -- V. 2: -- Brain tumors: general considerations -- Brain tumors: an overview of current histopathologic classifications -- Brain tumor immunology and immunotherapy -- Brain tumor stem cells -- Proliferation markers in the evaluation of gliomas -- Molecular genetics and the development of targets for glioma therapy -- Growth factors in glial tumors -- The genetic origins of brain tumors -- Invasion in malignant glioma -- Angiogenesis and brain tumors: molecular targets and molecular scalpels -- Barriers to delivery of therapeutics to brain tumors -- Epidemiology of brain tumors -- Gene- and viral-based therapies for gliomas -- Clinical features: neurology of brain tumor and paraneoplastic disorders -- Radiologic features of central nervous system tumors -- Endovascular techniques for tumor embolization -- Brain tumors during pregnancy -- Principles of chemotherapy -- Brain tumor outcome studies: design and interpretation -- Frame and frameless stereotactic brain biopsy -- Basic principles of cranial surgery for brain tumors -- Basic principles of skull base surgery -- Surgical complications of brain tumors and their avoidance -- Navigation for brain tumors -- Endoscopic approaches to brain tumors -- Intraoperative magnetic resonance imaging -- Low-grade gliomas: astrocytoma, oligodendroglioma, and mixed glioma -- Malignant gliomas: anaplastic astrocytoma, glioblastoma multiforme, gliosarcoma -- Unusual gliomas -- Primitive neuroectodermal tumors -- Pineal tumors -- Medulloblastoma -- Meningiomas -- Meningeal sarcoma and meningeal hemangiopericytoma -- Acoustic neuroma -- Pituitary tumors: functioning and nonfunctioning -- Craniopharyngioma -- Epidermoid, dermoid, and neurenteric cysts -- Neoplastic meningitis -- Ventricular tumors -- Overview of skull base tumors -- Chordomas and chondrosarcomas -- Glomus tumors -- Neoplasms of the paranasal sinuses -- Esthesioneuroblastoma -- Trigeminal schwannomas -- Juvenile nasal angiofibroma -- Osseous tumors -- Tumors of the orbit -- Skull tumors -- Scalp tumors -- Pseudotumor cerebri -- Sarcoidosis, tuberculosis, and xanthogranuloma -- Demyelinating disease -- Pain: general historical considerations -- Anatomy and physiology of pain -- Molecular basis of nociception -- Approach to the patient with chronic pain -- Pharmacologic treatment of pain -- Management of pain by anesthetic techniques -- Evidence-based approach to the treatment of facial pain -- Trigeminal neuralgia: diagnosis and nonoperative management -- Percutaneous procedures for trigeminal neuralgia -- Stereotactic radiosurgery for trigeminal neuralgia -- Microvascular decompression for trigeminal neuralgia -- Neurosurgical management of intractable pain -- Evidence base: neurostimulation for pain -- Peripheral nerve stimulation for neuropathic pain -- Spinal cord stimulation -- Motor cortex stimulation -- Evidence base for destructive procedures -- Diagnosis and management of painful neuromas -- Dorsal root entry zone lesions -- Percutaneous cordotomy and trigeminal tractotomy-nucleotomy -- Neuroanesthesia in children -- Neurocritical care in children -- Normal and abnormal embryology of the brain -- Encephalocele -- Dandy-Walker syndrome -- Arachnoid cysts -- Chiari malformations -- Craniopagus twins -- Genetics of craniosynostosis -- Craniosynostosis -- Syndromic craniosynostosis -- Endoscopic treatment of craniosynostosis -- Plagiocephaly -- Hydrocephalus in children: approach to the patient -- Infantile posthemorrhagic hydrocephalus -- Cerebrospinal fluid physiology -- Experimental hydrocephalus -- Ventricular shunting procedures -- Neuroendoscopy -- Cerebrospinal fluid devices -- Shunt infections and their treatment -- General approaches and considerations for pediatric brain tumors -- Optic pathway hypothalamic gliomas -- Thalamic tumors -- Choroid plexus tumors -- Pediatric craniopharyngioma -- Supratentorial hemispheric tumors -- Ependymoma -- Medulloblastoma in children -- Cerebellar astrocytomas -- Brainstem glioma -- Intracranial germ cell tumors -- Familial tumors (neurocutaneous syndromes) -- Skull tumors and fibrous dysplasia -- Moyamoya disease -- Vein of galen aneurysmal malformation -- Management of severe head injury in children -- Child abuse -- Growing skull fracture -- Birth head trauma -- Birth brachial plexus injury -- Myelomeningocele and myelocystocele -- Lipomyelomeningocele -- Split spinal cord -- Tethered spinal cord: fatty filum terminale, meningocele manque, and dermal sinus tracts -- Developmental abnormalities of the craniocervical junction -- Achondroplasia and other dwarfisms -- Cervical spine disorders in children -- Intramedullary spinal cord tumors in children -- Spine tumors in children -- Thoracolumbar spinal disorders in pediatric patients -- Vertebral column and spinal cord injuries in children -- Clinical features and management of cerebral palsy -- Intrathecal baclofen therapy for cerebral palsy -- Selective dorsal rhizotomy for spastic cerebral palsy -- Dystonia in children -- V. 3: -- General principles in evaluating and treating peripheral nerve pathology, injuries, and entrapments and their historical context -- Pathophysiology of surgical nerve disorders -- Peripheral nerve examination, evaluation, and biopsy -- Electrodiagnostic evaluation of peripheral nerves: electromyography and nerve conduction studies -- Peripheral neuropathies -- Operative neurophysiology of peripheral nerves -- Imaging for peripheral nerve disorders -- Distal entrapment syndromes: carpal tunnel, cubital tunnel, peroneal, and tarsal tunnel -- Thoracic outlet syndrome -- Piriformis syndrome, obturator internus syndrome, pudendal nerve entrapment, and other pelvic entrapments -- Techniques and options in nerve reconstruction and repair -- Management of acute peripheral nerve injuries -- Early management of brachial plexus injuries -- Secondary procedures for brachial plexus injuries -- Nerve injuries of the lower extremity -- Benign tumors of the peripheral nerve -- Surgery for malignant peripheral nerve sheath tumors -- Pain, complications, and latrogenic injury in nerve surgery -- General and historical considerations of radiotherapy and radiosurgery -- Principles of radiation therapy -- The radiobiology and physics of radiosurgery -- Fractionated radiation therapy for malignant brain tumors -- Fractionated radiation therapy for benign brain tumors -- Fractionated radiotherapy for spine tumors -- Interstitial and intracavitary irradiation of brain tumors -- Proton radiosurgery -- Linear accelerator radiosurgery: technical aspects -- Gamma knife radiosurgery -- Image-guided robotic radiosurgery: the CyberKnife -- Radiosurgery of malignant tumors -- Radiosurgery of benign intracranial tumors -- Radiosurgery for intracranial vascular malformations -- Radiosurgery for functional disorders -- Stereotactic radiosurgery for the treatment of spinal metastases -- Radiosurgery for benign spine tumors and vascular malformations -- Overview and historical considerations -- Concepts and mechanisms of spinal biomechanics -- Biomaterials and biomechanics of spinal arthroplasty -- Principles of translation of biologic therapies in spinal cord injury -- Current status and future direction of management of spinal cord injury -- Intraoperative monitoring of the spinal cord and nerve roots -- Concepts of disk degeneration and regeneration -- Bone metabolism and osteoporosis and its effects on spinal disease and surgical treatments -- Differential diagnosis and initial management of spine pathology -- Diagnosis and management of diskogenic lower back pain -- Metabolic and other nondegenerative causes of low back pain -- Evaluation, indications, and techniques of revision spine surgery -- Infections of the spine -- Fungal and tubercular infections of the spine -- Treatment of disk and ligamentous diseases of the cervical spine -- Posterior approach to cervical degenerative disease -- Anterior approach for cervical spondylotic myelopathy -- Spondyloarthropathies (including ankylosing spondylitis) -- Ossification of the posterior longitudinal ligament and other enthesopathies -- Treatment of thoracic disk herniation -- Treatment of disk disease of the lumbar spine -- Lumbar spine stenosis -- Pediatric spondylolisthesis -- Adult thoracolumbar scoliosis -- Flat back and sagittal plane deformity -- Acquired abnormalities of the craniocervical junction -- Congenital abnormalities of the thoracic and lumbar spine -- Basic principles of spinal internal fixation -- Bone graft options, bone graft substitutes, and bone harvest techniques -- Cervical arthroplasty -- Lumbar arthroplasty: total disk replacement and nucleus replacement technologies -- Nucleoplasty and posterior dynamic stabilization systems -- Spinopelvic fixation -- Anterior cervical instrumentation -- Occiput, C1, and C2 instrumentation -- Posterior subaxial and cervicothoracic instrumentation -- Anterior thoracic instrumentation -- Posterior thoracic instrumentation -- Anterior lumbar instrumentation -- Posterior lumbar instrumentation -- Posterior, transforaminal, and anterior lumbar interbody fusion: techniques and instrumentation -- Image-guided spinal navigation: principles and clinical applications -- Thoracoscopic approaches to the spine -- Minimally invasive techniques for lumbar disorders -- Tumors of the craniovertebral junction -- Spinal cord tumors in adults -- Evaluation and management of spinal axis tumors: benign and primary malignant -- Evaluation and management of spinal axis tumors: metastatic -- Assessment of the cervical spine after trauma -- Evaluation and management of craniocervical dissociation -- Atlantoaxial rotatory subluxation, transverse ligament injury -- Evaluation and treatment of odontoid and hangman's fractures -- Pathology of the cervicothoracic junction: evaluation and treatment -- Transient quadriparesis and athletic injuries of the cervical spine -- Diagnosis and management of thoracic spine fractures -- Thoracolumbar trauma -- Sacral fractures -- Osteoporotic fractures: evaluation and treatment with vertebroplasty and kyphoplasty -- V. 4: -- Introduction to traumatic brain injury -- Epidemiology of traumatic brain injury -- Biomechanical basis of traumatic brain injury -- Neuropathology of traumatic brain injury -- Animal models of traumatic brain injury -- Neurochemical pathomechanisms in traumatic brain injury -- Regeneration and repair -- Current concepts of hypothermia in traumatic brain injury -- Imaging of traumatic brain injury -- Clinical pathophysiology of traumatic brain injury -- Mild traumatic brain injury in adults and concussion in sports -- Initial resuscitation, prehospital care, and emergency room care in traumatic brain injury -- Critical care management of traumatic brain injury -- Surgical management of traumatic brain injury -- Traumatic and penetrating head injuries -- Blast-induced neurotrauma -- Indications and techniques for cranial decompression after traumatic brain injury -- Craniofacial injuries -- Prognosis after traumatic brain injury -- Traumatic cerebrospinal fluid fistulas -- Rehabilitation of patients with traumatic brain injury -- Cerebral blood flow and metabolism and cerebral ischemia -- Acute medical management of ischemic/hemorrhagic stroke -- Intraoperative cerebral protection -- Circulatory arrest with deep hypothermia -- Transcranial doppler ultrasonography and neurosonology -- Neurovascular imaging -- Carotid occlusive disease: natural history and medical management -- Carotid endarterectomy -- Carotid artery angioplasty and stenting -- Blunt cerebrovascular injury -- Nonatherosclerotic carotid lesions -- Extracranial vertebral artery diseases -- Intracranial occlusive disease -- Adult moyamoya disease -- Cerebral venous and sinus thrombosis -- Nonlesional spontaneous intracerebral hemorrhage -- Genetics of intracranial aneurysms -- The natural history of cerebral aneurysms -- Surgical decision making for the treatment of intracranial aneurysms -- Pathobiology of intracranial aneurysms -- Surgical decision making for the treatment of intracranial aneurysms -- Perioperative management of subarachnoid hemorrhage -- Cerebral vasospasm -- Surgical approaches to intracranial aneurysms -- Microsurgery of paraclinoid aneurysms -- Intracranial internal carotid artery aneurysms -- Anterior communicating artery aneurysms -- Microsurgery of distal anterior cerebral artery aneurysms -- Surgical management of middle cerebral artery aneurysms -- Microsurgery of vertebral artery, posterior inferior cerebellar artery, and vertebrobasilar junction aneurysms -- Basilar trunk aneurysms -- Microsurgery of basilar apex aneurysms -- Endovascular approaches to intracranial aneurysms -- Endovascular coiling of intracranial aneurysms: supporting evidence -- Endovascular stenting of intracranial aneurysms -- Endovascular hunterian ligation -- Microsurgical management of giant intracranial aneurysms -- Infectious intracranial aneurysms -- Revascularization techniques for complex aneurysms and skull base tumors -- Multimodality management of complex cerebrovascular lesions -- Traumatic cerebral aneurysms secondary to penetrating intracranial injuries -- Pathobiology of true arteriovenous malformations -- The natural history of intracranial vascular malformations -- Therapeutic decision making -- Adjuvant endovascular management of brain arteriovenous malformations -- Endovascular management of arteriovenous malformations for cure -- Microsurgical management of arteriovenous malformations -- Surgical and radiosurgical management of giant arteriovenous malformations -- Carotid-cavernous fistulas -- Treatment of other intracranial dural arteriovenous fistulas -- Natural history of cavernous malformations -- Genetics of cerebral cavernous malformations -- Supratentorial and infratentorial cavernous malformations -- Classification of spinal arteriovenous lesions: arteriovenous fistulas and arteriovenous malformations -- Endovascular treatment of spinal vascular malformations -- Spinal vascular malformations -- Pregnancy and the vascular lesion.
  • This book reviews the anatomy, imaging, and variety of surgical modalities available for the full spectrum of presentations of hip disease. Coverage ranges from problems in childhood and adolescence that limit activity, all the way through to sports-related problems with articular cartilage, the labrum, and impingement.
  • The controversial seat of myself -- A simple architecture of the brain -- Seeing through oneself : brain imaging -- Dispersed memories -- The prevention of Parkinson Disease -- The treatment of Alzheimer Disease -- The cerebrovascular accident -- The fatality of tumors -- Altered states of consciousness -- The myth of the artificial brain -- The power and the fragility of oneself.
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    Making the right medical choices is harder than ever. Whether deciding on a cholesterol drug or choosing a cancer treatment, we are overwhelmed by information from all sides: our doctors' recommendations, dissenting expert opinions, confusing statistics, conflicting media reports, the advice of friends, claims on the Internet, and a never-ending stream of drug company ads. This book shows us how to chart a clear path through this sea of confusion. Drs. Groopman and Hartzband reveal that each of us has a set of deeply rooted beliefs whose profound influence we may not realize when we make medical decisions. Recognizing our preferences and the external factors that might lead our thinking astray can make a dramatic, even lifesaving, difference in our medical decision making. The authors drew on research and insights from patients, doctors, psychologists, economists, and other experts to help reveal the array of forces that can aid or impede our thinking--From publisher description.
  • The book is a ready reckoner aimed at the student community aspiring to take up a career in bioinformatics. The book firstly provides a perspective on the domain and addresses the challenges faced by community namely the attempts to understand data produced by genome sequencing projects. It then brings to light High Performance Computing (HPC) as it helps in interpreting and analyzing genome sequences. The book also dwells on how interactions in a systems (organism), the components that interact with each other and the outcome of such interactions. It then calls for a consensus on the tools like rapid and inexpensive DNA sequencing technologies, HAPMAP projects, Dollar One Genome (DOG), to enable a reader understand how bioinformatics transits from research, to vocation and avocation. Further it extols the virtues of in silico for bioinformatical predictions as it helps wet-lab biologists reduce time for experiments. Also it describes the intricacies of bioinformatics and its usefulness to wet-based biologists and other cross-disciplinarians. The book lists out 10 reasons for taking up bioinformatics as a career, and includes insights from global experts on the domain. It also makes a case for a mediocre student getting into bioinformatics with discipline, determination, dynamism and diligence. The book further describes BioinformaTICKS a tool for emerging as a winner in bioinformatics.
  • This bibliography reviews what has been written in the literature on the topic of youth violence for the past ten years. It focuses on the professional literature but newspaper articles have also been included. Its primary focus is youth violence in the United States with the exclusion of violence as it relates to war trauma. The citations are mainly in English or Spanish. URLs have been provided for those citations that link back to PubMed, ERIC, and other systems.
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A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more. Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available.DynaMed is a clinical information resource used by physicians to answer clinical questions quickly and easily at the point of care. Topics are updated daily as new evidence becomes available. Scopus is the largest abstract and citation database of peer-reviewed literature: scientific journals, books and conference proceedings.A drug information resource containing: American Hospital Formulary System (AHFS), drug formulary for Lucile Packard Children's Hospital (LPCH) and Stanford Hospital & Clinics (SHC), Lexi-Drugs (adverse reactions, dosage and administration, mechanism of action, storage, use, and administration information), Lexi-Calc, Lexi-ID, Lexi-I.V. Compatibility (King Guide), Lexi-Interact, and Lexi-PALS.Cumulative Index to Nursing and Allied Health Literature (CINAHL) contains coverage of nursing and allied health literature.A knowledge database that provides access to topic reviews based on over 6000 clinically relevant articles. The evidence-based content, updated regularly, provides the latest practice guidelines in 59 medical specialtiesProvides critical assessments of systematic reviews compiled from a variety of medical journals.Selects from the biomedical literature original studies and systematic reviews that are immediately clinically relevant and then summarizes these articles in an enhanced abstract with expert commentary.Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences. Includes cited reference searching, citation maps, and an analyze tool.Features systematic reviews that summarize the effects of interventions and makes a determination whether the intervention is efficacious or not. Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.Provides systematic coverage of the psychological literature from the 1800s to the present through articles, book chapters and dissertations.BMJ Clinical Evidence. A clinical information tool built around systematic reviews summarizing the current state of knowledge about prevention and treatment of clinical conditions.PIER (Physicians' Information and Education Resource) is a Web-based decision-support tool designed for rapid point-of-care delivery of up-to-date, evidence-based guidance for primary care physicians.Cochrane Central Register of Controlled Trials (CENTRAL) provides access to 300,000 controlled trials that have been identified the Cochrane Collaboration.Provides drug information targeted for patients.A continually updating drug monograph.The National Guideline Clearinghouse (NGC): A comprehensive database of evidence-based clinical practice guidelines and related documents.MedlinePlus: A repository of health information from the National Library of Medicine. Links are from trusted sites. No advertising, no endorsement of commercial companies or productsLPCH CareNotes via MicroMedex: Patient education handouts customized by LPCH clinical staffMicromedex Lab Advisor: Evidence based laboratory test informationA drug database organized by generic name, trade name and drug class.LPCH / Stanford Hospital Formulary.A goldmine of trusted consumer health information from the world's largest medical library.A trusted source of expert advice for and about kids, providing the information necessary to help patients and parents understand their unique needs.Provides patient handouts from the American Academy of Family Physician.Access to the Stanford Health Library for patients.Lane provides access to over 5,000 eBooks many of which provide helpful background material that will prepare you to better tackle primary literature.Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities. In addition to covering Wiley and Springer, MyiLibrary is also the only provider for Oxford and Cambridge University Press titles. No seat restrictions.A collection of biomedical books that can be searched directly by concept, and linked to terms in PubMed abstracts.A web-based, decision support system for infectious diseases, epidemiology, microbiology and antimicrobial chemotherapy. The database, updated weekly, currently includes 337 diseases, 224 countries, 1,147 microbial taxa and 306 antibacterial (-fungal, -parasitic, -viral) agents and vaccines. Over 10,000 notes outline the status of specific infections within each country.
Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users.Vast collection of software and database programming titles from multiple publishers, including Microsoft Press.Largest provider of engineering-related eBooks; includes titles in computer science and biomedical engineering.Over 4,000 full-text e-books covering scientific and technical information from CRC Press and others. Many handbooks and single volume reference sources.Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals.Contains full text access to selected biomedical and nursing books.Provides online, full-text access to Springer's journal titles as well as journals from other publishers. Subjects include: life sciences, chemical sciences, environmental sciences, geosciences, computer science, mathematics, medicine, physics and astronomy, engineering and economics. Also includes eBooks.Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present.A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.