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- Fabry disease — Finely dispersed particles micro-, nano-, and atto-engineering (134)
- Fingertip injuries diagnosis, management and reconstruction — Food science and food biotechnology (134)
- Food shelf life stability chemical, biochemical, and microbiological changes — Frozen section library. Appendix, colon, and anus (134)
- Frozen section library. Bone — Fuzzy expert systems and fuzzy reasoning (133)
- Food spoilage microorganisms 2006CRCnetBASEpt. 1. Detection and analysis of food spoilage -- pt. 2. Managing food spoilage -- pt. 3. Spoilage yeasts -- pt. 4. Spoilage moulds -- pt. 5. Spoilage bacteria.
- Food toxicology 2001CRCnetBASE
- Food, diet and obesity 2005CRCnetBASE
- Food-borne pathogens methods and protocols 2006Springer ProtocolsDetection of hemolysins in Aeromonas spp. isolates from food sources / Rosabel Falcón ... [et al.] -- Detection and purification of Bacillus cereus enterotoxins / Toril Lindbäck and Per Einar Granum -- Campylobacter / Rachel Gorman and Catherine C. Adley -- Detection of Clostridium botulinum by multiplex PCR in foods and feces / Miia Lindström, Mari Nevas, and Hannu Korkeala -- Multiplex PCR for the specific identification of enterohemorrhagic Escherichia coli strains in the O157:H7 complex / Peter C.H. Feng and Steven R. Monday -- Pulsenet's step-by-step laboratory protocol for molecular subtyping of Listeria monocytogenes by macrorestriction and pulsed-field gel electrophoresis / Lewis M. Graves and Balasubramanian Swaminathan -- Plesiomonas shigelloides / Ivan Ciznar ... [et al.] -- Pulsed-field gel electrophoresis as a molecular technique in Salmonella epidemiological studies / Rachel Gorman and Catherine C. Adley -- Kits for the detection of food poisoning toxins produced by Bacillus cereus and Staphylococcus aureus / Moira M. Brett -- Microbiological and molecular methods to identify and characterize toxigenic Vibrio cholerae from food samples / Keya De, Ranjan K. Nandy, and G. Balakrish Nair -- HPLC measurement of aflatoxin B1 and metabolites in isolated rat hepatocytes / Jennifer Colford -- Detection of noroviruses of genogroups I and II in drinking water by real-time one-step rRT-PCR / Christian M. Beuret -- Detection of enteroviruses / Miguel-Angel Jiménez-Clavero ... [et al.] -- Detection of hepatitis A virus and rotavirus using nucleic acid sequence-based amplification / Julie Jean and Ismaïl Fliss -- Isolation and characterization of cathepsin-L1 protease from Fasciola hepatica excretory/secretory products for the serodiagnosis of human fasciolosis / Sandra O'Neill, Grace Mulcahy, and John Dalton -- Molecular biology methods for detection and identification of Cryptososporidium species in feces, water and shellfish / C.J.P. Lowery ... [et al.] -- Molecular identification of nematode worms from seafood (Anisakis spp. and Pseudoterranova spp.) and meat (Trichinella spp.) / Giuseppe La Rosa, Stefano D'Amelio, and Eduardo Pozio -- Approaches to developing quantitative risk assessment models / Enda J. Cummins -- A review of surveillance networks of food-borne diseases / Camelia Molnar, Rita Wels, and Catherine C. Adley.
- Food-drug synergy and safety 2006CRCnetBASE
- "These guidelines have been written for public health practitioners, food and health inspectors, district and national medical officers, laboratory personnel and others who may undertake or participate in the investigation and control of foodborne disease outbreaks."--P. 4 of cover.
- Foodborne diseases 2007SpringerEscherichia coli / Jianghong Meng and Carl M. Schroeder -- Listeria / Franz Allerberger -- Clostridium botulinum and Clostridium perfringens / Jim McLauchlin and Kathie A. Grant -- Yersinia enterocolitica and Yersinia pseudotuberculosis / Maria Fredriksson-Ahomaa -- Foodborne pathogenic vibrios / T. Ramamurthy and G. Balakrish Nair -- Enterococcus and its association with foodborne illness / Simona F. Oprea and Marcus J. Zervos -- Foodborne viral hepatitis / Hazel Appleton ... [et al.] -- Gastroenteric virus / Miren Iturriza-Gómara, Chris I. Gallimore, and Jim Gray -- Cryptosporidium / Huw V. Smith -- Toxoplasma gondii / Dolores E. Hill ... [et al.] -- Aflatoxins : background, toxicology, and molecular biology / Joan W. Bennett, S. Kale, and Jiujiang Yu -- Scombroid fish poisoning / Elijah W. Stommel -- Pathogen control in meat and poultry production: implementing the USDA food safety and inspection service's hazard analysis and critical control point system / Moshe S. Dreyfuss ... [et al.] -- Use of antimicrobials in food animal production / Frank M. Aaestrup and Lars B. Jensen -- Alternatives to antimicrobials* / Toni L. Poole, Todd R. Callaway, and David J. Nisbet -- Microbial risk assessment / Carl M. Schroeder -- Food irradiation and other sanitation procedures / Donald W. Thayer -- Molecular techniques of detection and discrimination of foodborne pathogens and their toxins / Steven L. Foley and Kathie A. Grant -- Future directions in food safety* / Ross C. Beier and Suresh D. Pillai.
- Foodborne parasites 2006Springer
- Foodborne pathogens hazards, risk analysis, and control 2002CRCnetBASE
- Foot and ankle in rheumatoid arthritis 2006SpringerDiagnosis of rheumatoid arthritis at an early stage / P. Miossec and J. Tebib, p. 1-8 -- The Rheumatoid foot. Pathomechanics, clinical and radiological features. Therapeutic conditions / M. Bouysset and P. Hugueny, p. 9-48 -- Some reflections on pathomechanics of the rheumatoid foot and ankle / X. Crevoisier, p. 49-72 -- CT and MRI in rheumatoid arthritis (midfoot, hindfoot and ankle) / Th. Tavernier, p. 73-95 -- Management of the patient with rheumatoid arthritis / J. Tebib and P. Miossec, p. 97-109 -- Footwear for the rheumatoid foot and ankle / M. Bouysset, P. Hugueny, G. Guaydier-Souquières and F. Lapeyre, p. 111-121 -- Corticosteroid injections and synoviortheses of the foot and ankle in rheumatoid arthritis / M. Bouysset, P. Hugueny, B. Gintz, J. Jalby and J. Tebib, p. 123-130 -- Forefoot surgery for rheumatoid arthritis / Y. Tourné, p. 131-147 -- Hindfoot surgery for rheumatoid arthritis / B. Valtin and Th. Leemrijse, p. 149-167 -- Points of view about synovectomy of the ankle joint in rheumatoid arthritis / H. Thabe, p. 169-178 -- Total ankle replacement. History, evolution of concepts, designs and surgical technique / M. Bonnin, T. Judet, T. Siguier and J. Colombier, p. 179-200 -- Some reflections about the evolution of ankle prosthesis / H. Kofoed, p. 201-206 -- Total ankle replacement in rheumatoid arthritis: treatment strategy / M. Bonnin, M. Bouysset, J. Tebib and E. Noël, p. 207-219 -- Respective indications of talocrural arthrodesis and ankle prosthesis with different situations in rheumatoid arthritis / K. Tillmann and B. Fink, p. 221-228 -- Surgical strategy in surgery of the lower limb in rheumatoid arthritis / W. Souter, p. 229-236 -- Surgery of the foot and ankle in patients with rheumatoid arthritis: some reflexions / F. Koeck, G. Heers, W. Caro and J. Grifka, p. 237-46.
- Foot and ankle surgery 2010ClinicalKeyHallux Valgus Correction with Modified Chevron Osteotomy -- Scarf Osteotomy for Correction of Hallux Valgus -- Modified "Lapidus" Procedure-Tarsometatarsal Corrective Osteotomy and Fusion with First Metatarsophalangeal Joint Correction and Realignment -- Proximal Long Oblique (Ludloff) First Metatarsal Osteotomy with Distal Soft Tissue Procedure -- Hallux Rigidus: Cheilectomy with and without a Dorsiflexion Phalangeal Osteotomy -- Arthrodesis of the Great Toe Metatarsophalangeal Joint -- Forefoot Reconstruction for Rheumatoid Disease -- Fifth Metatarsal Osteotomy for Correction of Bunionette Deformity -- Turf Toe Repair: Capsular Repair of First Metatarsophalangeal Plantar Plate Rupture -- Morton's Neuroma -- Revision Surgery through a Plantar Approach for Recurrent Interdigital Neuroma -- Deviated Lesser Toe/Metatarsal Shortening (Weil) Osteotomy -- Correction of Acquired Hallux Varus -- Arthroscopy of the Great Toe -- Metatarsal Lengthening -- Internal Fixation of the Sesamoid Bone of the Hallux -- Cavovarus Correction in Charcot-Marie-Tooth Disease -- Charcot Neuroarthropathy of the Midfoot/Hindfoot -- Midfoot Arthrodesis in Charcot Foot Deformity with "Charcot Screws" -- Open Reduction and Internal Fixation of Lisfranc/Tarsometatarsal Injuries -- Painful Accessory Navicular: Augmented Kidner Procedure with Flexor Digitorum Longus Transfer -- Painful Accessory Navicular Treated with Fusion -- Open Reduction and Internal Fixation of Proximal Fifth Metatarsal (Jones' or Stress) Fracture -- Open Reduction and Internal Fixation of the Cuboid Fracture/Nutcracker Injury -- Total Ankle Arthroplasty with a Current Three-Component Design (HINTEGRA Prosthesis) -- Salvage of Failed Total Ankle Arthroplasty -- Ankle Arthrodesis for Salvage of the Failed Total Ankle Arthroplasty -- Ankle Arthrodesis Using Ring/Multiplanar External Fixation -- Arthroscopic Ankle Arthrodesis -- Rigid Fixation for Ankle Arthrodesis Using Double Plating -- Tibiotalocalcaneal Fusion with a Retrograde Intramedullary Nail -- Realignment Surgery for Valgus Ankle Osteoarthritis -- Osteochondral Lesion of the Ankle-OATS Procedure -- Mosaicplasty with Bone-Periosteum Graft from the Iliac Crest for Osteochondral Lesions of the Talus -- Arthroscopy of the Subtalar Joint -- Modified Brostrom Procedure for Lateral Ankle Laxity -- Lateral Ankle Ligament Reconstruction Using Plantaris Autograft -- Salvage of a Failed Lateral Ligament Repair -- Lateral Ankle Reconstruction with the Fourth Extensor Digitorum Communis Tendon -- Ligament Reconstruction for Chronic Medial Ankle Instability -- Ligament Reconstruction for Chronic Medial Ankle Instability -- Exosectomy for Haglund's Disease -- Haglund's Deformity: Open and Arthroscopic Treatment -- Intra-articular Calcaneus Fractures -- Calcaneus Open Reduction and Internal Fixation with Extensile Lateral Incision -- Osteotomies for the Correction of Varus Ankle -- Tarsal Tunnel Syndrome -- Anterior Ankle Impingement -- Lateral Calcaneal Lengthening Osteotomy for Supple Adult Flatfoot -- Single Medial Approach for Triple Arthrodesis -- Triple Arthrodesis -- Treatment of Distal Achilles (Insertional) Degeneration and Associated Calf Tightness Plus Calcaneal Tuber Exostosis -- Achilles Tendon Reconstruction with Flexor Hallucis Longus Transfer Augmentation -- Peroneal Tendon Tears: Débridement and Repair -- Chronic Peroneal Tendon Subluxation-Dislocation -- Posterior Tibial Tendon Transfer for Footdrop -- Calf Lengthening for Equinus Contracture -- Proximal Tibia Bone Graft -- Anterior Leg Compartment Release for Exertional Compartment Syndrome.
- Foot and mouth disease the 1967 outbreak and its aftermath 2003Wellcome Trust
- Foot-and-mouth disease virus 2005Springer
- Footmarks of innate immunity in the ovary and cytokeratin-positive cells as potential dendritic cells 2011SpringerThe cyclic ovary can be seen as a site of tissue damage, repair and precisely controlled tissue homeostasis, as long ovulation and luteolysis can be compared with acute and chronic inflammation. Innate immunity appears to be a powerful force in the endocrine system, representing a novel concept. In this monograph, remarkable evidence is given for the immune-privileged ovary being an implant on the chicken chorioallantoic membrane with an areactive mesenchyme. Mild to severe tissue damages due to follicular atresia, follicular rupture, or intraovarian oocyte release do no lasting harm. The most exciting part relates to the analysis of cytokeratin-positive (CK<sup>+</sup>) cells, comparing the fate mapping of this cell type from the fetal ovary to the adult organ. Findings on toll-like receptor 4 regulation and interferon-gamma-dependent positive effects indicate that CK<sup>+</sup> cells from human preovulatory follicles and bovine corpora lutea have similarities with nonlymphoid dendritic cells, a discovery that has the makings of a top story in basic and clinical research on the ovary.
- Carollia perspicillata, a tropical species, is the only bat that has essentially been domesticated and can be maintained and propagated in a research environment utilizing simple, inexpensive husbandry procedures. This atlas contains the first quality treatment of a bat species, and is unique in its use of NeuN staining. The NeuN preparations used selectively stain neurons in a sharp black coloration that fills not only the cell body but extends a short distance along the proximal dendrites. Thus, as distinct from the traditional nissl stains, the NeuN generates a quasi Golgi-like image of the neurons, providing a more intimate view of the neurons than can be obtained from nissl staining. In addition, the background is essentially white, facilitating high-contrast photography and allowing for gray-tone illustration without any loss of information. The NeuN procedure does not stain axons, and since it does not stain glial cells or their nuclei, the noise ordinarily generated in nissl stains by the presence of glial cells among the neurons and in the white matter is entirely eliminated. The Forebrain Atlas of the Short-tailed Fruit Bat also includes nissl stained sections for comparison. Since it is known that NeuN is not expressed in certain neurons, such as Purkinje cells, olfactory bulb mitral cells, and the cells of the paraventricular and supraoptic nuclei, the nissl stained sections are also included to provide complementary views of such structures.
- Forefoot reconstruction. 2nd ed. 2005Springer
- Forensic anthropology and medicine complementary sciences from recovery to cause of death 2006Springer
- Forensic anthropology laboratory 2008CRCnetBASEIntroduction / Heather Walsh-Haney -- The Anthropology Research Facility, University of Tennessee / Lee Meadows Jantz and Richard L. Jantz -- The forensic anthropology laboratory in a medical examiner setting / Dana Austin and Laura Fulginiti -- Joint POW/MIA Accounting Command's Central Identification Laboratory / Thomas Holland, John Byrd and Vincent Sava -- The University of Indianapolis Archeology & Forensics Laboratory / Stephen P. Nawrocki -- The mass fatality incident morgue : a laboratory for disaster victim identification / Paul S. Sledzik and Patricia J. Kaufmann -- The Repatriation Osteology Laboratory at the Smithsonian Institution / Erica B. Jones and Stephen D. Ousley -- History and collections of the Division of Physical Anthropology, Smithsonian Institution / David R. Hunt -- The LSU Forensic Anthropology and Computer Enhancement Services Laboratory / Mary H. Manhein ... [et al.] -- The working forensic anthropology laboratory / Heather Walsh-Haney, Laurel Freas and Michael Warre.
- Forensic art and illustration 2001CRCnetBASE
- Forensic cardiovascular medicine 2009CRCnetBASE
- Forensic DNA evidence interpretation 2005CRCnetBASE
- Evolution of the written word -- Principles of handwriting -- Factors that cause changes in handwriting -- Handprinting and numerals -- History of document examination -- Forgery -- Other types of fraud -- Equipping a laboratory -- Care and handling of documents -- Standards of comparison -- Systematic examination of handwriting -- Master pattern -- Detecting fraudulent documents -- Weighing the evidence -- Preparing reports -- Alteration of documents -- Disguised writing -- Disguise versus simulation -- Check and credit card fraud -- Paper -- Writing instruments -- Seals, stamps, and paper -- Typewriters and printers -- Duplicating methods -- Desktop publishing -- The discovery process -- The litigation process -- Demonstrative evidence -- Court cases.
- Forensic emergency medicine. 2nd ed. 2007OvidPerpetrators / John E. Douglas and Mark Olshaker -- The Victims of violence / Carroll Ann Ellis -- Interviewing techniques / Peggy L. Johnson and John S. O'Brien II -- Forensic emergency medicine: penetrating trauma / William S. Smock -- Forensic aspects of motor vehicle trauma / William S. Smock -- Forensic examination of adult victims and perpetrators of sexual assault / Judith A. Linden, Annie Lewis-O'Connor, and M. Christine Jackson -- Sexual abuse and sexual assault of adolescents / V. Jill Kempthorne -- Child sexual assault: the acute assessment / Mary-Theresa L. Baker -- Child abuse/assault / Richard Lichenstein and Adrienne H. Suggs -- Elder abuse / Adam J. Geroff and Jonathan S. Olshaker -- Treating survivors of intimate partner abuse: forensic identification and documentation / Daniel J. Sheridan -- New drugs of abuse / K. Sophia Dyer -- Serology and DNA evidence / Rosalind Bowman, Teri J. Labbe, and Kimberly A. Mullings -- Law enforcement / Donald E. Steinhice -- Sexual assault and the criminal justice system / Sharon A.H. May -- Testifying / Sharon A.H. May -- Forensic photography in the emergency department / William S. Smock and Patrick E. Besant-Matthews.
- Forensic epidemiology 2010CRCnetBASE
- Forensic evidence science and the criminal law 2001CRCnetBASE
- Forensic evidence science and the criminal law. 2nd ed. 2006CRCnetBASE
- Introduction -- Staining Techniques and Microscopy -- Histopathology of Selected Trauma -- Histopathology and Drug Abuse -- Toxin- and Drug-Induced Pathologies -- Alcohol-Related Histopathology -- Heat, Fire, Electricity, Lightning, Radiation, and Gases -- Hypothermia -- Thrombosis and Embolism -- Vitality, Injury Age, Determination of Skin Wound Age, and Fracture Age -- Aspiration and Inhalation -- Forensic-Histological Diagnosis of Species, Gender, Age, and Identity -- Coronary Sclerosis, Myocardial Infarction, Myocarditis, Cardiomyopathy, Coronary Anomalies, and the Cardiac Conduction System -- Vascular, Cardiac Valve, and Metabolic Diseases -- Lethal Infections, Sepsis, and Shock -- Endocrine Organs -- Pregnancy-Related Death, Death in Newborns, and Sudden Infant Death Syndrome -- Forensic Cytology -- Histothanatology: Autolysis, Putrefaction, Mummification -- Forensic Neuropathology.
- Forensic human identification an introduction 2007CRCnetBASEsection 1. Identification from biomolecular evidence -- section 2. Identification from latent prints -- section 3. Identification from the soft tissues -- section 4. Identification from the hard tissues -- section 5. Facial identification -- section 6. Identification from methods of communication -- section 7. Identification from podiatry and walking -- section 8. Identification from personal effects -- section 9. The Context of forensic human identification -- section 10. Forensic human identification case studies.
- The problem of auto theft / Mikel Longman -- Victim and witness interviews and collection of circumstantial information / Jean-François Chevalley, Manuel Poza -- General crime scene considerations and documentation / Moira Johnson, Simone Reynolds -- Forensic examination of stolen-recovered vehicles : technical examination and general forensic traces / Marc Demierre ; Chemical traces--drugs, explosives, and gunshot residue / Francesco Saverio Romolo -- Traces and their evidentiary value / Eric Stauffer -- Vehicle identification / William T. Smylie -- Restoration of serial numbers / Horst Katterwe -- Anti-theft systems / Robert F. Mangine -- Examination of steering columns and ignition locks / Robert F. Mangine -- Examination of vehicle keys / Emmanuel Fivaz, Monica S. Bonfanti -- Analysis of vehicle fluids / Eric Stauffer -- Examination of burned vehicles / Eric Stauffer -- Examination of vehicles recovered underwater / Jean-François Voillot -- Examination of vehicle license plates / Didier Brossier -- Examination of vehicle registration documents / Diana Ombelli -- Vehicle searching procedures / Stéphane Kummer -- Examination of vehicles involved in terrorism / Greg Terp -- Investigation from the public side / Greg Terp -- Investigation from the private side : the European perspective / Marc Stauffer ; The U.S. perspective / Glenn Wheeler -- Vehicle tracking / Greg Terp -- Vehicle crime mapping / Jerry Ratcliffe -- International collaboration through Interpol / Alain G. Barbier.
- Forensic issues in alcohol testing 2008CRCnetBASEMeasuring acute alcohol impairment / Christopher S. Martin -- Update on clinical and forensic analysis of alcohol / Alan Wayne Jones and Derrick J. Pounder -- Post-mortem alcohol: aspects of interpretation / Derrick J. Pounder and Alan Wayne Jones -- Recent advances in biochemical tests for acute and chronic alcohol consumption / Anders Helander and Alan Wayne Jones -- Alcohol determination in point of collection testing / J. Robert Zettl.
- Forensic laboratory handbook procedures and practice 2006SpringerSerology and DNA / Lisa A. Gefrides and Katherine E. Welch -- Forensic chemistry / Donnell Christian -- Crime reconstruction / W. Jerry Chisum -- Digital evidence / Robert P. Bianchi and Mark Pollitt -- Explosives and arson : boom and flame / James B. Crippin -- Fingerprints / Brian E. Dalrymple -- Firearms and tool marks / Edward E. Hueske -- Forensic odontology : teeth and their secrets / Helena Soomer / Forensic pathology / Joye Carter -- Assuring quality in the crime laboratory / William J. Tilstone -- Introduction to forensic document Examination / William L. Leaver -- Toxicology in the crime laboratory / Ashraf Mozayani -- Trace evidence in the real crime lab / Richard E. Bisbing.
- Forensic linguistics advances in forensic stylistics 2002CRCnetBASE
- Forensic medical investigation of motor vehicle incidents 2007CRCnetBASE
- Forensic medicine fundamentals and perspectives 2014SpringerIntroduction -- The External Postmortem Examination -- Thanatology -- Autopsy (Syn. Postmortem Examination, Necroscopy) -- Exhumation -- Establishing Identity -- Vital Reactions -- Blunt Force Trauma -- Pointed, Sharp, and Semi-sharp Force Trauma -- Gunshot and Blast Wounds -- Neck Trauma -- Thermal Injury -- Electricity, Lightning, and Gases -- Asphyxia -- Water-Related Deaths -- Death by Starvation and Dehydration -- Clinical Forensic Medicine -- Child Abuse -- Child Sexual Abuse -- Infanticide and Neonaticide -- Traffic Medicine -- Forensic DNA Analysis -- Forensic Osteology -- Forensic Radiology -- Special Case Constellations in Natural, Unexplained, and Unnatural Deaths -- Torture -- Forensic Psychopathology -- Medical Malpractice -- Forensic Alcohology -- Forensic Toxicology.
- Forensic medicine of the lower extremity human identification and trauma analysis of the thigh, leg, and foot 2005SpringerThe decomposition of human remains: a biochemical perspective / Robert H. Powers -- Forensically significant skeletal anatomy / Nancy E. Tatarek and Dorothy E. Dean -- Normal osteology of the knee joint and markers of stress and injury / Emily A. Craig -- Anthropological analysis of the lower extremity: etermining sex, race, and stature from skeletal elements / Nancy E. Tatarek and Paul W. Sciulli -- Estimating age at death / Douglas H. Ubelaker -- Radiology of the lower extremity / B.G. Brogdon -- Injuries to children: a surgeon's perspective / Jonathan I. Groner -- Skeletal trauma analysis of the lower extremity / Alison Galloway and Lauren Zephro -- Biomechanics of impact injury / David J. Porta -- Injuries of the thigh, knee, and ankle as reconstructive factors in road traffic accidents / Grzegorz Teresiński -- Biomechanical analysis of slip, trip, and fall accidents / Scott D. Batterman and Steven C. Batterman -- "The game is afoot": feet help solve forensic puzzles in the United States and overseas / Julie Mather Saul and Frank P. Saul -- The role of feet and footwear in medicolegal investigations / John A. DiMaggio -- Ongoing research into barefoot impression evidence / Robert B. Kennedy.
- Forensic neuropathology and associated neurology 2006SpringerIntroduction -- Risks, responsibilities and liabilities -- Cytology of the CNS -- Cell and tissue reactions -- Methods in forensic neuropathology -- Basic principles of mechanical trauma -- Injuries of the brain's coverings -- Open brain injuries -- Closed brain injuries -- Injuries of spine and spinal cord -- Injuries of peripheral nerves -- Special physical trauma -- Hypoxia, ischemia (hypoglycemia) -- Forensic types of ischemia and asphyxia -- Permanent global ischemia -- Introductory remarks -- Specific types of neurotoxins -- Alcohol, organic solvents, and aerosols -- Illegal drugs and drug dependence -- Basic principles -- Fetal neuropathology -- Perinatal CNS injury -- Postnatal natural CNS death -- Postnatal mechanical brain injury (MBI) -- Physical abuse -- Basic principles -- Seizures and epilepsy -- Vascular diseases -- Inflammatory diseases -- Nutritional and metabolic insults -- Aging and brain pathology.
- The "complete autopsy" : the management of risk -- Postmortem changes : the "great pretenders" -- Asphyxia -- Thermal injury -- Bodies recovered from water -- Penetrating trauma: close-range firearm wounds -- Penetrating trauma: sharp force injuries -- Blunt trauma : with reference to planes, trains, and automobiles -- Craniocerebral trauma and vertebrospinal trauma -- Sudden neurological death.
- Forensic pathology. 2nd ed. 2001CRCnetBASE
- Forensic psychiatry influences of evil 2006SpringerOrganizations as evil structures / Dave Holmes and Cary Federman -- The psychopharmaceutical complex / Brian Kean -- Intention, excuse, and insanity / Tamas Pataki -- An archaeology of the "psychopath": the medicalization of evil / Tom Mason -- The comforts of evil: dangerous personalities in high-security hospitals and the horror film / Mick McKeown and Mark Stowell-Smith -- Madness, badness, and evil / Deidre N. Greig -- Destruction as a constructive choice / David A. Winter -- Violence as secular evil: forensic evaluation and treatment of violent offenders from the viewpoint of existential depth psychology / Stephen A. Diamond -- Scapegoat, spectacle, and confessional: close encounters with sex offenders and other species of dangerous individuals / Dave Mercer and Joel Richman -- The villification of victimized children in historical perspective / Victoria Van Slyke -- Evil: a clinical perspective / J. David Kinzie -- Capacities and dispositions: what psychiatry and psychology have to say about evil / Gwen Adshead -- Should radical evil be forgiven? / Marguerita La Caze -- Mad, bad, and evil: psychiatry, psychoanalysis, and evil / Michael Levine -- Talking about evil, even when it's not supposed to exist / C. Fred Alford -- The influence of evil on forensic clinical practice / Tom Mason, Joel Richman, and Dave Mercer -- Hope in the face of evil / Geri Miller and Ron Hood.
- Forensic recovery of human remains archaeological approaches 2006CRCnetBASE
- Forensic science an illustrated dictionary 2004CRCnetBASE
- "This book contains basic forensic information necessary for healthcare professionals to assess and manage victims of trauma and criminal behavior. Chapters cover information on types of wounds and how to describe them; various types of evidence which may be encountered in the healthcare setting; and general principles of evidence collection. Common evidentiary items such as clothing, foreign objects, trace evidence, biological evidence, and bite marks are discussed and collection procedures are identified."--Provided by publisher.
- Forensic speaker identification 2002CRCnetBASE
- Forensic uses of digital imaging 2001CRCnetBASE
- Forfar & Arneil's Textbook of pediatrics. 7th ed. 2008ClinicalKey
- Print MaterialPt. 1. Creating a grievance -- pt. 2. Forgiveness -- pt. 3. Forgive for good.
- Forgive for love the missing ingredient for a healthy and lasting relationship. 1st HarperCollins pbk. ed.Print MaterialOffers a seven-step program for creating and maintaining a lasting relationship that teaches forgiveness skills in order to resolve conflicts and increase happiness.
- Forgotten cure the past and future of phage therapy 2012Springer1. Helpful Little Bodies -- 2. Inside Stalin's Empire -- 3. The Fading of Phage Therapy -- 4. Naked Genes -- 5. 'They're Not a Panacea:' Phage Therapy in the Soviet Union and Georgia -- 6. In Poland: Phages for Diabetes? -- 7. The Renaissance of Phage Therapy -- 8. The Startups -- 9. Four Companies, Four Strategies -- 10. Cows and Chickens -- 11. Approval, At Last -- 12. In Treatment.
- Forgotten people, forgotten diseases the neglected tropical diseases and their impact on global health and development. 2nd ed. 2013ASMProvides an overview of the neglected tropical diseases (NTDs) and how they devastate the poor, essentially trapping them in a vicious cycle of extreme poverty by preventing them from working or attaining their full intellectual and cognitive development.
- FOXO1, T-cell trafficking and immune responses / Florent Carrette, Stéphanie Fabre and Georges Bismuth -- FOXP3 and its role in the immune system / Chang H. Kim -- Molecular regulation of cellular immunity by FOXP3 / Alicia N. McMurchy ... [et al.] -- The biology of FOXP3 : a key player in immune suppression during infections, autoimmune diseases and cancer / Frances Mercer and Derya Unutmaz -- The cooperative roles of FOXC1 and FOXC2 in cardiovascular development / Tsutomu Kume -- FOXO proteins and cardiac pathology / Albert Wong and Elizabeth A. Woodcock -- The forkhead transcription factors play important roles in vascular pathology and immunology / Xiao-Feng Yang ... [et al.] -- Regulatory T cells, FOXP3 and atherosclerosis / Michal Entin-Meer, Arnon Afek and Jacob George -- FOXP genes, neural development, speech and language disorders / Hiroshi Takahashi, Kaoru Takahashi and Fu-Chin Liu -- Pathophysiological relevance of forkhead transcription factors in brain ischemia / Kohji Fukunaga and Norifumi Shioda -- New insights for FOXO and cell-fate decision in HIV infection and HIV associated neurocognitive disorder / Min Cui ... [et al.] -- FOXP3+ regulatory T-cells in chronic kidney disease : molecular pathways and clinical implications / Pascal Meier -- Transcriptional role of FOXO1 in drug resistance through antioxidant defense systems / Tomoko Goto and Masashi Takano -- FOXP3 expressing regulatory T-cells in allergic disease / Kayhan T. Nouri-Aria -- Human clinical phenotype associated with FOXN1 mutations / Claudio Pignata, Anna Fusco and Stefania Amorosi -- FOXL2 : at the crossroads of female sex determination and ovarian function / Bérénice A. Benayoun ... [et al.] -- FOXO transcription factors : from cell fate decisions to regulation of human female reproduction / Jan J. Brosens, Miranda S.C. Wilson and Eric W.-F. Lam -- The "O" class : crafting clinical care with FOXO transcription factors / Kenneth Maiese ... [et al.].
- Formulating poorly water soluble drugs 2012Springer1. Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs / Stephanie Bosselmann and Robert O. Williams III -- 2. Optimizing the Formulation of Poorly Water-Soluble Drugs / Kevin P. O'Donnell and Robert O. Williams III -- 3. Solid-State Techniques for Improving Solubility / Justin R. Hughey and Robert O. Williams III -- 4. Mechanical Particle-Size Reduction Techniques / Javier O. Morales, Alan B. Watts, and Jason T. McConville -- 5. Solubilized Formulations / Feng Zhang and James C. DiNunzio -- 6. Injectable Formulations of Poorly Water-Soluble Drugs / Michael P. Boquet and Dawn R. Wagner -- 7. Design and Development of Self-Emulsifying Lipid Formulations for Improving Oral Bioavailability of Poorly Water-Soluble and Lipophilic Drugs / Ping Gao -- 8. Structured Development Approach for Amorphous Systems / Navnit Shah, Harpreet Sandhu, Duk Soon Choi, Oskar Kalb, Susanne Page, and Nicole Wyttenbach -- 9. Melt Extrusion / James C. DiNunzio, Feng Zhang, Charlie Martin, and James W. McGinity -- 10. Spray-Drying Technology / Dave A. Miller and Marco Gil -- 11. Pharmaceutical Cryogenic Technologies / Wei Yang, Donald E. Owens III, and Robert O. Williams III -- 12. Precipitation Technologies for Nanoparticle Production / Jasmine M. Rowe and Keith P. Johnston -- 13. Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs / Justin R. Hughey and James W. McGinity -- 14. Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs / Zedong Dong and Hasmukh Patel.
- Fostering nurse-led care professional practice for the bedside leader from Massachusetts General Hospital 2013ebrary"Nurse leaders exist at every level--from the bedside to the boardroom. But these days, nurse leaders and managers face major changes in health care delivery models that pressure them to improve patient care but at the same time improve efficiency and lower costs. Add to this the demand to provide nursing education and improve retentions, and the pressure can mount and create additional problems for your organization. The solution? Fostering Nurse-Led Care--from three of Massachusettes General Hospital's top nurse executives--tells nurse leaders and care providers the secrets of the professional practice model that has improved system outcomes and increased patient, family, and staff satisfaction for nearly 20 years. The book provides details including developing, implementing, and evaluating a professional practice environment; optimizing quality standards; implementing patient safety measurements and balancing cost with quality; building an effective learning environment; and resolving conflicts and ethical dilemmas"--Page 4 of cover.
- Print Material
- "Originally, the global exporting of psychology was considered a means of bringing science and modernism to underdeveloped parts of the world. In response, indigenous psychology has emerged as an alternative to the individual-focused theories and therapies of Western cultures, as well as a critique of the idea that the tenets of Western thought apply to all nations. The first full-length work analyzing its Confucian roots, Foundations of Chinese Psychology strips away the myths and assumptions that can impede reliable scholarship while supplying the context necessary for decoding complex, longstanding traditions of behavior. The author re-interprets the widely held idea of collectivism (which is often defined as the absence of individualism) in favor of the more descriptive relationism, using the structure of Confucian ethics as a lens for testing theories and understanding findings on Chinese social relationships. Elaborating on key concepts such as guanxi (personal connection) and face (social standing), the book offers both a specific paradigm for studying non-Western cultures and a model for indigenous psychologies worldwide. Included in the coverage: The Confucian model of mind and the way of humanity; Confucian relationalism and social exchange; Life goals and achievement motivation in Confucian society; Ethics, morality, and the concept of face; Guanxi and organizational behavior. Indigenous Chinese models of conflict resolution. Foundations of Chinese Psychology is a landmark volume of immediate interest to researchers, particularly members of the American Psychological Association, the Asian Association of Indigenous and Cultural Psychology, the International Academy of Intercultural Research, and similar organizations."--Publisher's website.
- Print Material
- Print MaterialThe beginning of computational genomics -- Finding sequence similarities -- Homology: can we get it right? -- Getting ready for the era of comparative genomics: the importance of viruses -- The first fact of comparative genomics: protein sequences are remarkably resilient in evolution -- The second fact of comparative genomics: functional convergence at the molecular level -- Prediction of function and reconstruction of metabolism from genomic data: homology-based approaches -- Prediction of function and reconstruction of metabolism: post-homology approaches -- Structural genomics: what does it tell us about life? -- How many protein families are there? -- Phylogenetic inference and the era of complete genomes -- Two stories about evolution -- Minimal and ancestral genomes -- Comparative genomics and systems biology.
- Foundations of genetic algorithms 6 2001ScienceDirectMachine generated contents note: Introduction -- Worthy N. Martin and William M. Spears -- Overcoming Fitness Barriers in Multi-Modal Search Spaces 5 -- Martin J. Oates and David Come -- N iches in N K -Landscapes 27 -- Keith E. Mathia, Larry J. Eshelman, and J. David Schaffer -- New Methods for Tunable, Random Landscapes 47 -- R. E. Smith and J. E. Smith -- Analysis of Recombinative Algorithms on a Non-Separable Building-Block Problem 69 -- Richard A. Watson -- Direct Statistical Estimation of GA Landscape Properties 91 -- Colin R. Reeves -- Comparing Population Mean Curves 109 -- B. Naudts and I. Landrieu -- Local Performance of the ((/(I, () -ES in a Noisy Environment 127 -- Dirk V Arnold and Hans-Georg Beyer -- Recursive Conditional Scheme Theorem, Convergence and -- Population Sizing in Genetic Algorithms 143 -- Riccardo Poli -- Towards a Theory of Strong Overgeneral Classifiers 165 -- Tim Kovacs -- Evolutionary Optimization through PAC Learning 185 -- Forbes J. Burkowski -- Continuous Dynamical System Models of Steady-State Genetic Algorithms 209 -- Alden H. Wright and Jonathan E. Rowe -- Mutation-Selection Algorithm: A Large Deviation Approach 227 -- Paul Albuquerque and Christian Mazza -- The Equilibrium and Transient Behavior of Mutation and Recombination 241 -- William M. Spears -- The Mixing Rate of Different Crossover Operators 261 -- Adam Prigel-Bennett -- Dynamic Parameter Control in Simple Evolutionary Algorithms 275 -- Stefan Droste, Thomas Jansen, and Ingo Wegener -- Local Search and High Precision Gray Codes: Convergence Results and Neighborhoods 295 -- Darrell Whitley, Laura Barbulescu, and Jean-Paul Watson -- Burden and Benefits of Redundancy 313 -- Karsten Weicker and Nicole Weicker -- Author Index 335 -- Key Word Index 337.
- Foundations of sport-related brain injuries 2006Springer
- I. Foundations of Injury in Athletics -- Classification of Injuries in Athletics, p. 3-23 -- Science of Training and Injury in Athletics, p. 25-43 -- Balance as a Risk Factor for Athletic Injuries, p. 45-75 -- Fatigue-Related Injuries in Athletes, p. 77-95 -- Nutrition as a Risk Factor for Injury in Elite Athletes, p. 97-109 -- II. Coaches and Athletes' Perspectives of Injury -- Injury in Athletics: Coaches' Point of View, p. 113-146 -- Injury from Athletes' Perspectives, p. 147-159 -- Interviews with Injured Athletes, p. 161-195 -- Overuse Injuries: Students' Points of View, p. 197-216 -- Fitness Assessment in Athletes, p. 217-239 -- III. Psychological Traumas in Athletes -- Psychological Trauma: Unfortunate Experience in Athletics, p. 243-267 -- Fear as Adaptive or Maladaptive Form of Emotional Response, p. 269-287 -- Fear of Injury, Kinesiophobia & Perceived Risk, p. 289-309 -- Multiple Facets of Pain due to Injury, p. 311-330 -- Psychological Trauma: Case Studies, p. 331-355 -- Psychological Trauma: Age & Gender Factors, p. 357-374 -- IV. Concussion in Athletes -- Concussion: Why Bother?, p. 377-398 -- Concussion Classification: Historical Perspectives and Current Trends, p. 399-414 -- Evaluation of Concussion: Signs and Symptoms, p. 415-445 -- Traumatic Brain Injuries in Children, p. 447-466 -- V. Injury Rehabilitation -- Integrated Injury Rehabilitation, p. 469-491 -- EEG & Neurofeedback in Rehabilitation, p. 493-513 -- Virtual Reality in Injury Rehabilitation, p. 515-540.
- Foundations of systematics and biogeography 2008SpringerIntroduction: Systematics, evolution, and classification -- Systematics as problem solving -- The archetype -- Ernest Haeckel and systematische phylogenie -- The German development of morphology: from Ernest Haeckel to Willie Hanning -- Pattern Cladistics -- Homologues and homology -- Discovering homologues -- Homology and systematics -- Homology and transformation -- Character conflict -- The analyses of relationships -- Biogeograhical relationships, evolution, and classification.
- Fourier transforms in spectroscopy 2001Wileych. 1. Basic definitions -- ch. 2. General properties of Fourier transforms -- ch. 3. Discrete Fourier transform -- ch. 4. Fast Fourier transform (FFT) -- ch. 5. Other integral transforms -- ch. 6. Fourier transform spectroscopy (FTS) -- ch. 7. Nuclear magnetic resonance (NMR) spectrometry -- ch. 8. Ion cyclotron resonance (ICR) mass spectrometry -- ch. 9. Diffraction and Fourier transform -- ch. 10. Uncertainty principle -- ch. 11. Processing of signal and spectrum -- ch. 12. Fourier self-deconvolution (FSD) -- ch. 13. Linear prediction.
- "WHO's third decade was characterized by a sense of optimism, perhaps naive in retrospect. There was a feeling that progress was possible, not only in health, but in social and economic ways to improve individual and collective well-being. This optimism was reflected in the approval by the Thirtieth World Health Assembly in May 1977 of resolution WHA30.43, which stated that WHO's main social target for the coming decades should be for all citizens of the world to attain by the year 2000 a level of health to enable them to lead socially and economically productive lives."--Introduction, p. vii.
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- Fractal analysis is useful in digital image processing for the characterization of shape roughness and gray-scale texture or complexity. Breast masses present shape and gray-scale characteristics in mammograms that vary between benign masses and malignant tumors. This book demonstrates the use of fractal analysis to classify breast masses as benign masses or malignant tumors based on the irregularity exhibited in their contours and the gray-scale variability exhibited in their mammographic images. A few different approaches are described to estimate the fractal dimension (FD) of the contour of a mass, including the ruler method, box-counting method, and the power spectral analysis (PSA) method. Procedures are also described for the estimation of the FD of the gray-scale image of a mass using the blanket method and the PSA method.
- Fractal symmetry of protein exterior 2013SpringerIntroduction -- Characterization of Protein-Protein Interfaces, Considering Surface-Roughness and Local Shape -- Adhesion on Protein (and Other Rough Biomolecular) Surfaces.
- Fractal symmetry of protein interior 2013SpringerIntroduction -- Characterization of Protein-Protein Interfaces, Considering Surface-Roughness and Local Shape -- Adhesion on Protein (and Other Rough Biomolecular) Surfaces.
- Fractals in biology and medicine. Volume IV 2005Springer
- Fracture classifications in clinical practice 2006Springer
- Residents and junior doctors on rotation are under constant pressure to have accurate and up-to-date information available to them. This is never more important than when on rotation in the Emergency Room. Junior doctors often lack experience in orthopaedics making the recognition and accurate identification of fractures and their treatment a challenging task.The second edition of this comprehensive handbook contains a wealth of illustrations and explanatory text, which is organized into a concise repository of information on fractures according to the most widely used classification systems. The classification systems covered include AO and OTA systems. This allows readers the opportunity to make a correct diagnosis using the appropriate criteria, while simplifying the planning of further management and ensuring that communication with experienced staff is more effective.
- Fracture management for primary care. 3rd ed. 2012ClinicalKeyThe 3rd edition provides the guidance you need to evaluate and treat common fractures, as well as identify uncommon fractures that should be referred to a specialist. Drs. M. Patrice Eiff and Robert Hatch emphasize the current best guidelines for imaging and treating fractures so that you can make accurate identifications and select appropriate treatment. Detailed descriptions and illustrations combined with evidence-based coverage give you the confidence you need to make the right decisions. Reference key information quickly and easily thanks to one-page management tables that summarize pertinent aspects of diagnosis and treatment. Reference key information quickly and easily thanks to one-page management tables that summarize pertinent aspects of diagnosis and treatment. Effectively manage emergency situations using guidelines for emergent referral, greater detail regarding methods for closed reductions for fractures and dislocations, and more. Know how and when to treat fractures and when to refer your patients to a specialist.
- Print MaterialContents -- pt. 2. A contribution to the discussion on the treatment of calcaneus fracture based on an analysis of a ten-year material treated by closed reduction and traction, from Sentralsykehuset i Trondheim.
- Fracture-dislocations of the wrist 2013SpringerAccording to reports in the literature, despite the severe disruption of carpal anatomy, fracture-dislocations of the wrist are missed on clinical and radiographic examination in a high percentage of cases. Orthopedic surgeons' lack of familiarity with these injuries is one of the factors contributing to failed or delayed diagnosis. This richly illustrated book covers all types of wrist dislocation and fracture-dislocation. Detailed information is provided on anatomy and biomechanics, while terminology and classification of injuries are explained. Treatment options are thoroughly analysed, with special emphasis on surgical treatment, which is presented step by step. All of the figures -- radiological and surgical -- relate to patients treated by the author himself. Most of the cases are from the Red Cross Hospital of Athens that admits many patients with such injuries, in part through referral from other centres due to the author's acknowledged expertise in the field. This volume, with its highly informative and up-to-date chapters and reviews, and a wealth of color figures, will be of great practical value for clinicians and residents in orthopedic surgery, who assist them in daily decision making.
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- Recognized experts from around the world bring you "cutting-edge" guidance on the treatment of distal radius fractures and carpal injuries. Practical and comprehensive, you'll find detailed coverage of the treatment and causes of ulnar sided wrist pain, as well as the latest arthroscopic and mini-invasive techniques for the fixation of both distal radius fractures and scaphoid fractures. The user-friendly format features practical tips, pearls, and potential pitfalls to help optimize outcomes. Best of all, intraoperative videos of 44 techniques available on DVD and online make this an outstanding multimedia guide for the treatment of these challenging fractures. Uses real cases to illustrate diagnostic decision-making, nonsurgical and surgical management and care, and outcomes measurement for a variety of complex distal radius fractures, as well as 44 videos, over two hours, of procedures all on the DVD and website. Includes the fully-searchable text online for quick and easy access to the information you need. Covers distal radius fractures from imaging and classification to the new locking plate designs, emerging nonplate alternatives such as intramedullary and T-pin fixation, and newer nonbridging external fixators for intra-articular fractures to provide you with the latest developments in the field. Presents material in a concise, practical format for an ideal review before surgery. Provides a visual display of intraoperative procedures through full-color images and photographs. Features additional chapters, Role of Advanced Imaging in Distal Radius Fractures, Patient-focused Wrist Outcome Instrument, Biomechanics and Biology of Plate Fixation of Distal Radius Fractures, Micronail, Rehabilitation Following Distal Radius Fractures: a biomechanical/procedure specific approach, Use of Thermal Shrinkage: Biology and applications, Arthroscopic Thermal Shrinkage for Scapholunate Ligament Injuries, Rehabilitation following Carpal Injury, Reconstruction of the Distal Radius Facet by a Free Vascularized Ostechondral Graft, online for even more value.
- Pt. 1. The aging of bone and etiologies of fractures -- pt. 2. Perioperative management -- pt. 3. Common fractures in the elderly -- pt. 4. Rehabilitation, post-fracture evaluation, and prevention.
- Fractures of the proximal femur improving outcomes 2011ClinicalKeyMatch pre-operative assessment, surgical techniques, post-operative management, and more to the specific lifestyle factors of each patient in order to achieve optimal results. Apply state-of-the-art techniques and protocols with the visual help of operative videos as well as more than 500 surgical line drawings and photographs in print. Review surgical techniques such as pinning, plating/intramedulary devices, and total hip replacement implants, and get a greater understanding of deep vein thrombosis and pulmonary embolism prevention. Brush up on related topics including epidemiology, osteoporosis, co-morbidities, evidence-based post-op, and rehabilitation protocols. Get the advice of expert contributors worldwide who detail best practices in prophylaxis, surgical technique, and rehabilitation.
- Print MaterialIf reproductive hormones are so important, why is there so much variation? -- Coevolution of biology and culture : agriculture and selection for high levels of estrogens -- You are what you eat ... as a fetus -- The French paradox : did child welfare reduce the risk of heart disease? -- Intergenerational echoes of slavery -- The price of reproduction -- The ultimate test of costs of reproduction : life span -- Evolutionary past and modern diet -- Evolution and physical activity -- Evolutionary trade-offs and culture -- Fallacies of philanthropy -- Fixing genes versus fixing lifestyles.
- Fragile X-associated tremor ataxia syndrome (FXTAS) 2010SpringerClinical Neurological Phenotype of FXTAS / Maureen A. Leehey, Elizabeth Berry-Kravis, Christopher G. Goetz and Randi J. Hagerman -- The Epidemiology of FXTAS / Deborah A. Hall and Sebastien Jacquemont -- FXTAS: Neuropsychological/Neuropsychiatric Phenotypes / Jim Grigsby, Angela G. Brega, Andreea L. Seritan and James A. Bourgeois -- Radiological Findings in FXTAS / Susan M. Rivera, Glenn T. Stebbins and Jim Grigsby -- The Pathology of FXTAS / Claudia M. Greco, Michael R. Hunsaker and Robert F. Berman -- The Molecular Biology of FXTAS / Flora Tassone and Paul J. Hagerman -- Genotype/Phenotype Relationships in FXTAS / Emily Allen, Maureen A. Leehey, Flora Tassone and Stephanie Sherman -- Animal Models for FXTAS / Rob Willemsen, Yujing Li, Robert F. Berman, Judith R. Brouwer and Ben A. Oostra, et al. -- Treatment and Management of FXTAS / Elizabeth Berry-Kravis, Deborah A. Hall, Maureen A. Leehey and Randi J. Hagerman -- Genetic Counseling for FXTAS and FMR1-Associated Disorders / Louise W. Gane, Katherine Howard and Liane Abrams.
- Fragment-based drug design tools, practical approaches, and examples 2011ScienceDirectThere are numerous excellent reviews on Fragment Based Drug Discovery (FBDD), but there are to date no hand-holding guides or protocols with which one can embark on this orthogonal approach to complement traditional high throughput screening methodologies. This Methods in Enzymology volume offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD. Also elaborated by experienced researchers in FBDD are sample preparations of fragments, proteins, and GPCR as well as examples of how to generate leads from hits. Offers the tools, practical approaches, and hit-to-lead examples on how to conduct FBDD screens. The chapters in this volume cover methods that have proven to be successful in generating leads from fragments, including chapters on how to apply computational techniques, nuclear magnetic resonance, surface plasma resonance, thermal shift and binding assays, protein crystallography, and medicinal chemistry in FBDD.
- Fragmented intimacy addiction in a social world 2008SpringerPART 1: THEORY -- Addiction in Perspective -- Dangerous Consumptions -- Overview of this Book -- Companion Relationships -- A Social World -- Worlds, Paradigms and Assumptions -- The Particle Paradigm -- The Social Paradigm -- Switching to a Social World -- Addiction and Connecting -- Connecting to the World -- Patterns of Fragmentation -- Responding to Addiction -- The Prospect of Change -- Setting Out and Setting Back -- Making it Stick -- PART 2: PROCESSES -- Becoming Intimate -- Living in Relationships -- Intimacy and the "Four Cs" -- Special Considerations -- Quality Intimacy? -- Intimacies in Addictive Contexts -- Intimacy within Addictive Relationships -- Intimacies for Others -- Systems of Intimate Connections -- Intimacy and Power -- Controlling Tactics -- The Myth of Disinhibition -- Violence as a Social Event -- Managed Intimacy -- PART 3: FAMILIES & COMMUNITIES -- Fragmented Lives -- Fragmenting Environments -- How Intimates Respond -- Broader Social Dynamics -- Collective Opportunities -- Empowerment and Connectedness -- Reconnecting Intimates -- Responsibility for Change -- Change Processes -- Guidelines for Effective Collective Action -- Reintegration -- What is Reintegration? -- Six Phases of Reintegration -- Reforming Intimacies -- Enabling Closeness and Compassion -- Domains of Connectedness -- PART 4: APPLICATIONS -- Family Resources -- Social Resources from Inner Power -- Social Resources Offered by Services -- Mobilizing Communities -- Volunteer Networks -- Croatian/Italian Community Clubs -- An Indigenous Approach -- Applications to Practice -- Barriers to Social Inclusive Practice -- Social Engagement -- Social Assessment -- Facilitative Meetings -- Looking Ahead -- Where It Fits -- Future Opportunities
- Frailty : scaling from cellular deficit accumulation? / Rockwood, K.; Mitnitski, A. ; Howlett, S.E -- Assessment of frailty in animal models / Howlett, S.E. -- Frailty, inflammation, and immunosenescence / Fulop, T. ; McElhaney, J., Pawelec, G. ; Cohen. A.A ; Morais, J.A. ; Dupuis, G. ; Baehl, S. ; Camous, X. ; Witkowski, J.M. ; Larbi, A. -- Sex differences in frailty / Hubbard, R.E. -- Frailty and the microbiome / Meehan, C.J. ; Langille, M.G.I. ; Beiko, R.G. -- Operationalizing frailty using the frailty phenotype and deficit accumulation approaches / Theou, O. ; Walston, J. ; Rockwood, K. -- Comparison and clinical applications of the frailty phenotype and frailty index approaches / Theou, O. ; Rockwood, K. -- Frailty in primary care / Romero-Ortuno, R. -- Hospital care for frail elderly adults : from specialized geriatric units to hospital-wide interventions / Bakker, F.C. ; Olde Rikkert, M.G.M. -- Frailty and mobility / Eeles, E. ; Low Choy, N. -- Frailty and interprofessional collaboration / Briggs, M.C.E. ; McElhaney, J.E. -- Frailty and rehabilitation / Cameron, I.D. ; Kurrle, S.E. -- End of life care in frailty / Moorhouse, P. ; Koller, K. ; Mallery, L. -- Frailty and organization of health and social care / Clegg, A. ; Young, J. -- Frailty's place in ethics and law : some thoughts on equality, autonomy, and limits and on possibilities for aging citizens / McNally, M.; Lahey, W. -- Frailty and social vulnerability / Andrew, M.K.
- Frailty model 2008Springer
- Frailty models in survival analysis 2011CRCnetBASEThe concept of frailty offers a convenient way to introduce unobserved heterogeneity and associations into models for survival data. In its simplest form, frailty is an unobserved random proportionality factor that modifies the hazard function of an individual or a group of related individuals. Frailty Models in Survival Analysis presents a comprehensive overview of the fundamental approaches in the area of frailty models. The book extensively explores how univariate frailty models can represent unobserved heterogeneity. It also emphasizes correlated frailty models as extensions of univariate and shared frailty models. The author analyzes similarities and differences between frailty and copula models; discusses problems related to frailty models, such as tests for homogeneity; and describes parametric and semiparametric models using both frequentist and Bayesian approaches. He also shows how to apply the models to real data using the statistical packages of R, SAS, and Stata. The appendix provides the technical mathematical results used throughout. Written in nontechnical terms accessible to nonspecialists, this book explains the basic ideas in frailty modeling and statistical techniques, with a focus on real-world data application and interpretation of the results. By applying several models to the same data, it allows for the comparison of their advantages and limitations under varying model assumptions. The book also employs simulations to analyze the finite sample size performance of the models.--From the publisher's website.
- Free radical biology in digestive diseases 2011KargerFree radicals and lipid peroxidation / Niki, E. -- Mitochondria as source of free radicals / Majima, H.J. ... [et al.] -- The Nox family of NADPH oxidases that deliberately produce reactive oxygen species / Sumimoto, H., Minakami, R., Miyano, K. -- Neutrophil-dependent oxidative stress in inflammatory gastrointestinal diseases / Naito, Y., Yoshikawa, T. -- Oxidative DNA damage and carcinogenesis / Jiang, L., Toyokuni, S. -- Plasma marker of oxidative stress in circulation and in tissue / Yamamoto, Y. -- Immunochemical detection of 4-hydroxy-2-nonenal-specific epitopes / Uchida, K. -- Carbon monoxide-dependent regulation of microvascular function : one gas regulates another / Suematsu, M., Kajimura, M., Kabe, Y. -- Nrf2-Keap1 signaling as a prime chemopreventive target for antioxidative and anti-inflammatory phytochemicals / Surh, Y.-J. -- Free radicals and gastric mucosal injury / Ock, C.Y. ... [et al.] -- Free radicals in helicobacter pylori infection / Suzuki, H. ... [et al.] -- Free radical and nonsteroidal anti-inflammatory drug-induced small intestinal injury / Handa, O., Naito, Y. -- Free radicals in inflammatory bowel disease / Takagi, T., Naito, Y., Yoshikawa, T. -- Free radicals and chronic hepatitis C / Sakaida, I -- Free radicals and nonalcoholic fatty liver disease/nonalcoholic steatohepatitis / Sumida, Y., Naito, Y., Yoshikawa, T. -- Role of free radicals in pancreatitis / Hamada, S., Shimosegawa, T. -- Free radicals and cancer treatment / Kokura, S.
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- Frege and the logic of sense and reference 2002CRCnetBASE
- FRET and FLIM techniques 2009.ScienceDirect
- Freyschmidt's "Koehler/Zimmer" Borderlands of normal and early pathologic findings in skeletal radiography. 5th revised edition. 2003Medlantis
- Print MaterialExplores the tumultuous lives, marriage, and work of Mexican artists Frida Kahlo and Diego Rivera.
- From access to adherence the challenges of antiretroviral treatment : studies from Botswana, Tanzania and Uganda 2006Print Material
- From action to cognition 2007ScienceDirectPt. I. The structuring of the brain -- Unaltered development of the archi- and neocortex in prematurely born infants: genetic control dominates in proliferation, differentiation and maturation of cortical neurons / H. Ábrahám ... [et al.] -- Subcortical regulation of cortical development: some effects of early, selective deprivations / G.M. Innocenti -- The mirror-neurons system: data and models / L. Craighero ... [et al.] -- Apraxia: a review / B. Petreska ... [et al.] -- Pt. II. The early development of perception and action -- Effects of early visual deprivation on perceptual and cognitive development / D. Maurer, C.J. Mondloch, T.L. Lewis -- Visual tracking and its relationship to cortical development / K. Rosander -- Visual and visuocognitive development in children born very prematurely / J. Atkinson, O. Braddick -- Development of brain mechanisms for visual global processing and object segmentation / O. Braddick, J. Atkinson -- How face specialization emerges in the first months of life / F. Simon ... [et al.] -- The early development of visual attention and its implications for social and cognitive development / S. Hunnius -- Pt. III. The development of action and cognition -- Visual constraints in the development of action / G. Savelsbergh ... [et al.] -- Object and event representation in toddlers / R. Keen, K. Shutts -- Learning and development in infant locomotion / S.E. Berger, K.E. Adolph -- Core Systems in human cognition / K.D. Kinzler, E.S. Spelke -- Taking an action perspective on infant's object representations / G. Gredebäck, C. von Hofsten -- Pt. IV. The development of action and social cognition -- Infants' perception and production of intentional actions / P. Hauf -- The role of behavioral cues in understanding goal-directed actions in infancy / S. Biro, G. Csibra, G. Gergely -- Seeing the face through the eyes: a developmental perspective on face expertise / T. Gliga, G. Csibra -- Past and present challenges in theory of mind research in nonhuman primates / J. Call -- Infancy and autism: progress, prospects, and challenges / M. Elasbbagh, M.H. Johnson -- Children-robot interaction: a pilot study in autism therapy / H. Kozima, C. Nakagawa, Y. Yasuda -- Pt. V. The development of artificial systems -- Sensorimotor coordination in a "baby" robot: learning about objects through grasping / L. Natale ... [et al.] -- Emergence and development of embodied cognition: a constructivist approach using robots / Y. Kuniyoshi ... [et al.].
- From animals to animats 10 10th International Conference on Simulation of Adaptive Behavior, SAB 2008, Osaka, Japan, July 7-12, 2008 : proceedings 2008Springer
- From basic cardiac imaging to image fusion 2013SpringerThe recent development of three-dimensional imaging techniques has provided an enormous amount of information relevant to the clinical management of patients at low and high risk for coronary artery disease. However, while progress in each individual technique has been rapid, the correlation of findings obtained with radiology, nuclear medicine, and magnetic resonance imaging is still relatively neglected. In this book, qualified experts in cardiac imaging present the basic concepts of cardiac disease and imaging and compare the findings obtained in particular subspecialties with those acquired using other techniques. In this way the reader will learn how images and techniques can be integrated in clinical practice to the benefit of the patient. In addition, the issue is addressed of reducing the patient's exposure to ionizing radiation through appropriate multimodality integration. Physicians ranging from cardiac surgeons to internal medicine specialists and even public health administrators will find this book invaluable in understanding the role of hybrid cardiac imaging.
- Introduction: From Brains to the Machines of the Future / Ricardo Sanz, Carlos Hernández and Jaime Gómez-Ramirez -- Emergent Feature Sensitivity in a Model of the Auditory Thalamocortical System / Martin Coath, Robert Mill, Susan L. Denham and Thomas Wennekers -- STDP Pattern Onset Learning Depends on Background Activity / James Humble, Steve Furber, Susan L. Denham and Thomas Wennekers -- Emergence of Small-World Structure in Networks of Spiking Neurons Through STDP Plasticity / Gleb Basalyga, Pablo M. Gleiser and Thomas Wennekers -- Coupling BCM and Neural Fields for the Emergence of Self-organization Consensus / Mathieu Lefort, Yann Boniface and Bernard Girau -- Alpha and Theta Rhythm Abnormality in Alzheimer's Disease: A Study Using a Computational Model / Basabdatta Sen Bhattacharya, Damien Coyle and Liam P. Maguire -- Oscillatory Neural Network for Image Segmentation with Biased Competition for Attention / Tapani Raiko and Harri Valpola -- Internal Simulation of Perceptions and Actions / Magnus Johnsson and David Gil -- Building Neurocognitive Networks with a Distributed Functional Architecture / Marmaduke Woodman, Dionysios Perdikis, Ajay S. Pillai, Silke Dodel and Raoul Huys, et al. -- Reverse Engineering for Biologically Inspired Cognitive Architectures: A Critical Analysis / Andreas Schierwagen -- Competition in High Dimensional Spaces Using a Sparse Approximation of Neural Fields / Jean-Charles Quinton, Bernard Girau and Mathieu Lefort -- Informational Theories of Consciousness: A Review and Extension / Igor Aleksander and David Gamez -- Hippocampal Categories: A Mathematical Foundation for Navigation and Memory / Jaime Gómez-Ramirez and Ricardo Sanz -- The Role of Feedback in a Hierarchical Model of Object Perception / Salvador Dura-Bernal, Thomas Wennekers and Susan L. Denham -- Machine Free Will: Is Free Will a Necessary Ingredient of Machine Consciousness? / Riccardo Manzotti -- Natural Evolution of Neural Support Vector Machines / Magnus Jändel -- Self-conscious Robotic System Design Process - From Analysis to Implementation / Antonio Chella, Massimo Cossentino and Valeria Seidita -- Simulating Visual Qualia in the CERA-CRANIUM Cognitive Architecture / Raúl Arrabales, Agapito Ledezma and Araceli Sanchis -- The Ouroboros Model, Selected Facets / Knud Thomsen.
- Cancer survivors -- The medical and psychological concerns of cancer survivors after treatment -- Delivering cancer survivorship care -- Providers of survivorship care: their supply and education and training -- Employment, insurance, and economic issues -- Research.
- From fragments to objects segmentation and grouping in vision 2001ScienceDirectThe concept of an "object" in perception and cognition / Robert Schwartz -- Balls of wax and cans of worms : the early history of object perception / Margaret Atherton -- Perceptual unit formation in infancy / Martha E. Arterberry -- Perceptual units and their mapping with language / Barbara Landau -- An object substitution theory of visual masking / James T. Enns and Vincent Di Lollo -- Attention and unit formation : a biased competition account of object-based attention / Shaun P. Vecera and Marlene Behrmann -- Geometric and neural models of object perception / Philip J. Kellman, Sharon E. Guttman, and Thomas D. Wickens -- Varieties of grouping and its role in determining surface layout / Barbara Gillam -- Amodal completion : a case study in grouping / Allison B. Sekuler and Richard F. Murray -- Perceptual organization as generic object recognition / David W. Jacobs -- Simplicity, regularity, and perceptual interpretations : a structural information approach / Rob Van Lier -- Computational neural models of spatial integration in perceptual grouping / Heiko Neumann and Ennio Mingolla -- Part-based representations of visual shape and implications for visual cognition / Manish Singh and Donald D. Hoffman -- Gaze control for face learning and recognition by humans and machines / John Henderson ... [et al.] -- The visual interpretation of object and human movement / Maggie Shiffrar -- Contours from apparent motion : a computational theory / William Prophet, Donald Hoffman, and Carol Cicerone -- Breathing illusions and boundary formation in space-time / Nicola Bruno -- Perception of occluding and occluded objects over time : spatiotemporal segmentation and unit formation / Thomas F. Shipley and Douglas W. Cunningham.
- From innate immunity to immunological memory 2006SpringerTLR signaling / S. Akira -- Dendritic cells : translating innate to adaptive immunity / R.M. Steinman and H. Hemmi -- Helper T cell-regulated B cell immunity / L.J. Mcheyzer-Williams, L.P. Malherbe, and M.G. McHeyzer-Williams -- T cell memory / J.T. Tan an C.D. Surh -- The privacy of T cell memory to viruses / R.M. Welsh ... [et al.] -- Enhancement of infectious disease vaccines through TLR9-dependent recognition of CpG DNA / M.J. McCluskie and A.M. Krieg.
- From local invasion to metastatic cancer involvement of distant sites through the lymphovascular system 2009Springer
- Print MaterialHippocrates / by Michael A. Shea -- The Valley's First Practitioner / by Michael A. Shea -- An Ohlone Birth / by Michael A. Shea -- Trephination in History / by Michael A. Shea -- Bloodletting / by Michael A. Shea -- Medical Care at Mission Santa Clara / by Gerald E. Trobough-- Gold Rush Medicine / by Michael A. Shea -- John Marsh the First American Practitioner in California / by Michael A. Shea -- John Townsend, Pioneer Doctor / by Michael A. Shea -- Benjamin Cory and other Pioneer Physicians. Part 1, Isaac Isbell / by Gerald E. Trobough -- The Cory Brothers Modernized Medicine in Santa Clara County -- Pioneer Physician of Santa Clara Township. Dr. Henry H. Warburton (1819-1903) / by Gerald E. Trobough -- Benjamin Cory and other Pioneer Physicians. Part 2, Louis Bascom / by Gerald E. Trobough -- Benjamin Cory and other Pioneer Physicians. Part 3, Alexander Spencer / by Gerald E. Trobough -- Pioneer Physicians of Los Gatos / by Gerald E. Trobough -- Keeley Institute / by Gerald E. Trobough -- Here Come the Lady Physicians / by Michael Shea -- The Cholera Epidemic-San Jose California 1850 / by elizabeth Ahrens-Kley -- A Famous Grizzley Bear Attack in 1854 / by Michael A. Shea -- Orificial Surgery / by Michael A. Shea -- Origins of the Medical Societies / by Gerald E. Trobough -- American's Greatest Surgeon? / by Gerald E. Trobough -- First Hospital in San Jose by Gerald E. Trobough -- The History of O'Connor Hospital / by Michael A. Shea -- The History of San Jose Hospital / by Michael A. Shea -- Tuberculosis Hospitals of Santa Clara Valley by Gerald E. Trobough -- UCSF Medical School-- the Beginning / by Michael A. Shea -- The Origin of Stanford Medical School / by Michael A. Shea -- Levi Cooper Lane (1830-1902) / by Michael A. Shea -- Agnews State Hospital / by Michael A. Shea -- Leon Parish Fox, MD-- Man of the Century / by Michael A. Shea.
- The origin and development of neural crest-derived melanocytes / Debra L. Silver and William J. Pavan -- MITF : a matter of life and death for the developing melanocytes / Heinz Arnheiter ... [et al.] -- MITF : critical regulator of the melanocyte lineage / Erez Feige, Laura L. Poling, and David E. Fisher -- Melanocytes and the transcription factor Sox10 / Michael Wegner -- Human cutaneous pigmentation : a collaborative act in the skin, directed by paracrine, autocrine, and endocrine factors and the environment / Zalfa A. Abdel-Malek and Ana Luisa Kadekaro -- Melanocyte distribution and function in human skin : effects of ultraviolet radiation / Yuji Yamaguchi and Vincent J. Hearing -- Altered signal transduction in melanoma / Pablo López Bergami, Anindita Bhoumik, and Ze'ev Ronai -- BRN2 in melanocytic cell development, differentiation, and transformation / Anthony L. Cook ... [et al.] -- The dynamic roles of cell-surface receptors in melanoma development / Dong Fang and Meenhard Herlyn -- Familial melanoma genes, melanocyte immortalization, and melanoma initiation / Dorothy C. Bennett -- Genetic progression from melanocyte to malignant melanoma / Boris C. Bastian -- The multiple roles of the oncogenic protein SKI in human malignant melanoma / Dahu Chen ... [et al.] -- RB/E2F regulation and dual activity in the melanocytic system / Ruth Halaban -- Melanoma development and pigment cell transformation / Claudia Wellbrock -- The biology and genetics of melanoma / Norman E. Sharpless and Lynda Chin -- The biology of xeroderma pigmentosum : insights into the role of ultraviolet light in the development of melanoma / James E. Cleaver -- Divergent pathways to cutaneous melanoma / David C. Whiteman and Adéle C. Green -- Pigmentation, DNA repair, and candidate genes : the risk of cutaneous malignant melanoma in a mediterranean population / Maria Teresa Landi -- Low-penetrance genotypes, pigmentation phenotypes, and melanoma etiology / Peter A. Kanetsky and Timothy R. Rebbeck -- The biology of melanoma progression : from melanocyte to metastatic seeds / A. Neil Crowson, Cynthia Magro, and Martin C. Mihm, Jr. -- Optical imaging analysis of atypical nevi and melanoma / Amanda Pfaff Smith and Dorothea Becker -- Proteomics analysis of melanoma cell lines and cultured melanocytes / Katheryn A. Resing and Natalie G. Ahn -- Paradigm of metastasis for malignant melanoma / Stanley P.L. Leong -- Repair of UV-induced DNA damage and melanoma risk / Qingyi Wei -- High risk factors for melanoma metastasis / Neil A. Accortt and Seng-jaw Soong -- Role of melanoma inhibitory activity in early development of malignant melanoma / Anja-Katrin Bosserhoff -- Role and regulation of PAR-1 in melanoma progression / Carmen Tellez and Menashe Bar-Eli -- Molecular mechanisms of melanoma metastasis / Mohammed Kashani-Sabet -- Overview of tumor progression in melanoma / David E. Elder -- The plasticity of melanoma cells and associated clinical implications / Mary J. C. Hendrix ... [et al.] -- The clinical use of molecular markers as predictors of disease outcome and response to therapy in malignant melanoma / Steve R. Martinez, Hiroya Takeuchi, Dave S.B. Hoon -- The role of DCT/TYRP2 in resistance of melanoma cells to drugs and radiation / Brian J. Pak and Yaacov Ben-David -- How melanoma cells evade chemotherapy : role of transporter-dependent and -independent resistance mechanisms / Kevin G. Chen and Michael M. Gottesman -- Apoptosis in melanoma: approaches to therapy / Heicke Röckmann and Dirk Schadendorf -- Role of melanoma-associated antigens / Rishab K. Gupta, Ana M. McElrath-Garza, and Donald L. Morton -- Host responses to melanoma : implications for immunotherapy / Julian A. Kim and Ernest Borden -- Future perspectives / Vincent J. Hearing and Stanley P.L. Leong.
- From molecular to modular tumor therapy tumors are reconstructible communicatively evolving systems 2010Springer"The traditional problem of the poor presentability as well as diagnostic and therapeutic practicability of individual patient care is still unresolved. The present book aims at leading the reader (cancer researchers, pharmacologists, biologists) away-in a scientifically accessible manner-from the daily conflicts between theory and practice and between the generalized and individual tumor patient, so that more personalized diagnostic and therapeutic strategies can be developed for controlling metastatic tumor disease: First, recording the systems concept of tumor biology based on rather different sciences (biochemistry, cell biology, and medical oncology) including their potential contribution to communication, then, giving reductionistically derived systems features an internal communicative context (formal-pragmatic communication theory), and finally, binding the systems features to (tumor-immanent) evolutionary processes (modularity of biochemical and cellular processes, rationalization of biologic functions)"--Back cover.
- 1. Introduction -- 2. Carpal Tunnel Syndrome, Electroneurography, Electromyography, and Statistics -- 3. Tremor, Polymyography, and Spectral Analysis -- 4. Epilepsia, Electroencephalography, Filtering, and Feature Extraction -- 5. Multiple Sclerosis, Evoked Potentials, and Enhancing Signal-to-Noise Ratio -- 6. Cortical Myoclonus, EEG-EMG, Back-Averaging, and Coherence Analysis -- 7. Psychogenic Movement Disorders, Bereitschaftspotential, and Event-Related Potentials -- 8. Brain Tumor, Preoperative Function Localization, and Source Localization -- 9. Neuromuscular Diseases, Ultrasound, and Image Analysis -- 10. Cerebrovascular Disease, Ultrasound, and Hemodynamical Flow Parameters -- 11. Spinal Dysfunction, Transcranial Magnetic Stimulation, and Motor Evoked Potentials.
- From neuroscience to neurology neuroscience, molecular medicine, and the therapeutic transformation of neurology 2005ScienceDirect1. Seeing the brain so we can save it: the evolution of magnetic resonance imaging as a clinical tool -- 2. Advances in the acute treatment and secondary prevention of stroke -- 3. Preserving function in acute nervous system injury -- 4. Slowing the progression of multiple sclerosis -- 5. The Emergence of neurosurgical approaches to the treatment of epilepsy -- 6. The Neurobiology of migraine and transformation of headache therapy -- 7. Botulinum toxins: transformation of a toxin into a treatment -- 8. Prospects for slowing the progression of Parkinson's disease -- 9. Current neurosurgical treatments for Parkinson's disease: where did they come from? -- 10. Treatable peripheral neuropathies: plasma exchange, intravenous immunoglobulin, and other emerging therapies -- 11. Molecular pharmacology and the treatment of Tourette's syndrome and attention deficit-hyperactivity disorder -- 12. Neuroscience, molecular medicine, and new approaches to the treatment of depression and anxiety -- 13. Genomics, proteomics, and neurology -- 14. Neuroprotection: where are we going? -- 15. Prospects for gene therapy for central nervous system disease -- 16. Therapeutics development for hereditary neurological diseases -- 17. Inherited channelopathies of the CNS: lessons for clinical neurology -- 18. Inherited channelopathies of muscle: implications for therapy -- 19. Transcriptional channelopathies of the nervous system: new targets for molecular medicine -- 20. New molecular targets for the treatment of neuropathic pain -- 21. Therapeutic transfer and regeneration of neural progenitors or neurons in gray matter of the adult brain -- 22. Cellular plasticity of the adult human brain -- 23. Harnessing endogenous stem cells for central nervous system repair -- 24. Neuropathies-translating causes into treatments -- 25. Therapeutic potential of neurotrophic factors -- 26. Promoting the regeneration of axons within the central nervous system -- 27. Alzheimer's disease: clinical features, neuropathological and biochemical abnormalities, genetics, models, and experimental therapeutics -- 28. Behavioral intervention and recovery from CNS damage -- 29. What functional brain imaging will mean for neurology.
- From nucleic acids sequences to molecular medicine 2012SpringerRNAissance / Juergen Brosius -- Nucleic Acids as Therapeutics / Saraswat Pushpendra, Pareek Arvind and Bhandari Anil -- Thio Effects as a Tool for Mechanistic Studies of the Cleavage of RNA Phosphodiester Bonds: The Chemical Basis / Mikko Ora, Tuomas Lönnberg and Harri Lönnberg -- Off-Target Effects and Safety Aspects of Phosphorothioate Oligonucleotides / Martina Stessl, Christian R. Noe and Johannes Winkler -- Oligonucleotide Conjugates: Rationale, Synthesis, and Applications / Yashveer Singh, Pierre Murat, Nicolas Spinelli and Eric Defrancq -- CRISPR: A Bacterial Immunity System Based on Small RNAs / Rolf Wagner and Ümit Pul -- Antisense Technology: From Unique Laboratory Tool to Novel Anticancer Treatments / Christine Di Cresce, Colin Way, Mateusz Rytelewski, Saman Maleki Vareki and Supritha Nilam, et al. -- Antisense-Mediated Reduction of Eukaryotic Noncoding RNAs / Xue-hai Liang, Timothy A. Vickers and Stanley T. Crooke -- Antisense Oligonucleotides in the Treatment of Malignant Gliomas / Gerardo Caruso, Mariella Caffo, Giuseppe Raudino, Federica Raudino and Mario Venza, et al. -- Natural Antisense Transcripts Mediate Regulation of Gene Expression / Marco Magistri and Mohammad Ali Faghihi -- Activation and Deactivation of Antisense and RNA Interference Function with Light / Jeane M. Govan and Alexander Deiters -- Ribozymes as Molecular Biology Reagents / Sanchita Bhadra, Arti Pothukuchy and Andrew Ellington -- RNA Technologies for Mitochondrial Genetics / André Dietrich, Katarzyna Rolle, Marta Gabryelska, Eliza Wyszko and Romain Val, et al. -- RNA-Based Therapies for Inherited Metabolic Diseases / Belén Pérez, Magdalena Ugarte and Lourdes R. Desviat -- RNA-Cleaving DNA Enzymes and Their Potential Therapeutic Applications as Antibacterial and Antiviral Agents / P. I. Pradeepkumar and Claudia Höbartner -- Hammerhead Ribozymes Against Virus and Viroid RNAs / Alberto Carbonell, Ricardo Flores and Selma Gago -- Suppression of Hepatitis C Viral Genome Replication with RNA-Cleaving Deoxyribozyme / Dal-Hee Min and Dong-Eun Kim -- Design of Synthetic shRNAs for Targeting Hepatitis C: A New Approach to Antiviral Therapeutics / Brian H. Johnston and Qing Ge -- The Diverse Active Sites in Splicing, Debranching, and MicroRNA Processing Around RNA Phosphodiester Bonds / Sourav Kumar Dey, Eduardo Paredes, Molly Evans and Subha R. Das -- MicroRNAs and Their Antagonists as Novel Therapeutics / Jeppe Vinther, Jakob Lewin Rukov and Noam Shomron -- microRNAs in Human Diseases and Viral Infections / Alessandra Mescalchin and Tobias Restle -- Dysregulation of MicroRNA Expression and Human Diseases? / To-Ha Thai -- Noncoding RNAs: Identification of Cancer-Associated MicroRNAs / Muller Fabbri and George A. Calin -- Targeting Non-coding RNAs for Cancer Therapy / Satya K. Kota and Savithri Balasubramanian -- MicroRNA Pathways in Drosophila / Geetanjali Chawla and Nicholas S. Sokol -- Viroids: The Smallest Known Infectious Agents Cause Accumulation of Viroid-Specific Small RNAs / Jaroslav Matoušek, Detlev Riesner and Gerhard Steger.
- Print MaterialLondon apothecaries and other medical retailers / Patrick Wallis -- Medical advertising in the popular press / Louise Hill Curth -- Accessing drugs in the eighteenth century regions / Steve King -- "The doctor's shop" / Hilary Marland -- From "bespoke" to "off-the-peg" / Stuart Anderson -- "A cascade of medicine" / Judy Slinn.
- Section I: Generating and inferring structures. Ab Initio protein structure prediction / Jooyoung Lee, Sitao Wu, and Yang Zhang ; Fold recognition / Lawrence A. Kelley ; Comparative protein structure modelling / András Fiser ; Membrane protein structure prediction / Timothy Nugent and David T. Jones ; Bioinformatics approaches to the structure and function of intrinsically disordered proteins / Peter Tompa -- Section II: From structure to functions. Function diversity within folds and superfamilies / Benoit H. Dessailly and Christine A. Orengo ; Predicting protein function from surface properties / Nicholas J. Burgoyne and Richard M. Jackson ; 3D motifs / Elaine C. Meng, Benjamin J. Polacco, and Patricia C. Babbitt ; Protein dynamics: from structure to function / Marcus B. Kubitzki, Bert L. de Groot, and Daniel Seeliger ; Integrated servers for structure-informed function prediction / Roman A. Laskowski ; Case studies: Function predictions of structural genomics results / James D. Watson and Janet M. Thornton ; Prediction of protein function from theoretical models / Iwona A. Cymerman, Daniel J. Rigden, and Janusz M. Bujnicki.
- From signals to colours a case-based atlas of electroanatomic mapping in complex atrial arrhythmias ; based on the experience of the Project of ElectroAnatomic mapping in Complex arrhythmia Evaluation (PEACE) 2008Springer
- This book is designed as an easy to read reference and practical guide to the management of combat extremity injuries, which account for a high percentage of the injuries sustained in recent and current conflicts. The surgical techniques appropriate to the full range of extremity injuries and some other frequent injuries, such as trauma to the spine and pelvis, are clearly described with the aid of helpful illustrations. In each chapter a bottom line up front approach is adopted, providing key messages first; a further important feature is the emphasis placed on case-based information and lessons learned from practice. Care has been taken to ensure that the advice provided is straightforward and in line with military clinical practice guidelines.
- Front line surgery a practical approach 2011SpringerPrehospital and enroute care -- Combat triage and mass casualty management -- Initial management priorities: beyond ABCDE -- Damage control resuscitation -- To operate or image?: pulling the trigger -- Ultrasound in combat trauma -- The bowel: contamination, colostomies, and combat surgery -- Liver and spleen injury management in combat (old school) -- Pancreatic and duodenal injuries (sleep when you can ...) -- Operative management of renal injuries -- Major abdominal vascular trauma -- To close or not to close: managing the open abdomen -- Choice of thoracic incision -- Lung injuries in combat -- Diagnosis and management of penetrating cardiac injury -- Thoracic vascular injuries: operative management in "enemy territory" -- Chest wall and diaphragm injury -- Soft tissue wounds and fasciotomies -- Extremity injuries and open fractures -- Mangled extremities and amputations -- Peripheral vascular injuries -- The neck -- Geritourinary injuries (excluding kidney) -- Neurosurgery for dummies -- Spine injuries -- Face, eye, and ear injuries -- Burn care in the field hospital -- The pediatric patient in wartime -- The combat ICU team -- Postoperative resuscitation -- Monitoring -- Ventilator management: a practical approach to respiratory failure in combat casualties -- Practical approach to combat-related infections and antibiotics -- Stabilization and transfer from the far forward environment -- Humanitarian and local national care -- Expectant and end of life care in a combat zone.
- Frontal sinus 2005Springer
- Print MaterialOverview of mechanisms of resistance to anticancer agents / Michael P. Draper ... [et al.] -- Development of resistance to anticancer agents / David E. Modrak, Graham Jones, and Michael P. Draper -- The birth of the alliance for the prudent use of antibiotics (apua) / Ellen Koenig -- Alliance for the prudent use of antibiotics: scientific vision and public mission / Kathleen T. Young and Thomas F. O'Brien -- Antimicrobial use in animals in the United States: developments in policy and practice / Stephen J. DeVincent and Christina Viola -- From perplexing proteins to paratek pharmaceuticals: one scientific front forged / by Stuart B. Levy / Mark L. Nelson and S. Ken Tanaka. Phenicol resistance / Stefan Schwarz and David G. White -- Multiple antimicrobial resistance / Anthony M. George -- Metal resistance loci of bacterial pathogens / Anne O. Summers -- Biocides and resistance / Bonnie Marshall, Laura M. McMurry, and Merri C. Moken -- The nexus of oxidative stress responses and antibiotic resistance mechanisms in escherichia coli and salmonella / Bruce Demple -- The mar locus / Thamarai Schneiders, Herbert Haechler, and William Yan -- The mar regulon / Teresa M. Barbosa and Pablo J. Pomposiello -- Identification of mar mutants among clinical bacterial isolates / JoAnn Dzink-Fox and Margret Oethinger -- Structure and function of mara and its homologs / Robert G. Martin and Judah L. Rosner -- Function and structure of marr family members / Michael N. Alekshun and James F. Head -- Role, structure, and function of multidrug efflux pumps in gram-negative bacteria / Hiroshi Nikaido -- Role of multidrug efflux pumps in gram-positive bacteria / Glenn W. Kaatz -- Advances in vancomycin resistance: research in staphylococcus aureus / Keiichi Hiramatsu ... [et al.] -- Enterococcus / Roland Leclercq and Patrice Courvalin -- Streptococcus pneumoniae / Joyce Sutcliff and Marilyn C. Roberts -- Helicobacter and campylobacter / Patrick F. McDermott and Diane E. Taylor -- Anaerobes / Isabelle Podglajen, Jacques Breuil, and Ekkehard Collatz -- Pseudomonas aeruginosa / Keith Poole -- Antibiotic resistance in salmonella and shigella / E. J. Threlfall -- Antibiotic resistance in escherichia coli / Mark A. Webber and Laura J. V. Piddock -- Epidemiology and treatment options for select community-acquired and nosocomial antimicrobial-resistant pathogens / John E. Gustafson and John D. Goldman -- Drug-resistant falciparum malaria: mechanisms, consequences, and challenges / Karen Hayton ... [et al.] -- Antimicrobial susceptibility testing of bacterial agents of bioterrorism: strategies and considerations / Fred C. Tenover -- Fitness traits in soil bacteria / Fabrice N. Gravelat, Stephen R. Strain, and Mark W. Silby -- Ecology of antibiotic resistance genes / Abigail A. Salyers, Hera Vlamakis, and Nadja B. Shoemaker -- Resistance in the food chain and in bacteria from animals: relevance to human infections / Vincent Perreten -- Antimicrobial use in plant agriculture / Anne K. Vidaver -- Tetracycline resistance: efflux, mutation, and other mechanisms / Frederic M. Sapunaric, Mila Aldema-Ramos, and Laura M. McMurry -- Tetracycline resistance due to ribosomal protection proteins / Marilyn C. Roberts -- Discovery and industrialization of therapeutically important tetracyclines / Mark L. Nelson and Steven J. Projan -- Fluoroquinolone resistance / Jordi Vila -- [beta]-lactam resistance in the 21st century / George Jacoby and Karen Bush -- Macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone resistance / Marilyn C. Roberts and Joyce Sutcliff -- Aminoglycoside resistance mechanisms / David D. Boehr, Ian Moore, and Gerard D. Wright -- Glycopeptide resistance in enterococci / Florence Depardieu and Patrice Courvalin --
- Frontiers in biochip technology 2006Springer2006 MyiLibrary
- Frontiers in brain repair 2010SpringerIn vivo imaging of cellular transplants / Justin Chan ... [et al.] -- Culture and manipulation of neural stem cells / Jennifer Katz, Bryan Keenan, and Evan Y. Snyder -- Animal models of neurological disease / Amol Shah ... [et al.] -- Stem cell transplantation methods / Kimberly D. Tran, Allen L. Ho and Rahul Jandial -- Stem cell origin of brain tumors / Dawn Waters, Ben Newman, and Michael L. Levy -- The tumor microenvironment / Lissa Baird and Alexey Terskikh -- Exploitation of genetically modified neural stem cells for neurological disease / Allen L. Ho, Sassan Keshavarzi, and Michael L. Levy -- Biological horizons for targeting brain malignancy / Samuel A. Hughes .. [et al.] -- Stem cells in the treatment of stroke / Klaudia Urbaniak Hunter, Chester Yarbrough, and Joseph Ciacci -- Gene- and cell-based approaches for neurodegenerative disease / Klaudia Urbaniak Hunter, Chester Yarbrough, and Joseph Ciacci.
- Frontiers in celiac disease 2008KargerHistorical perspective of celiac disease / Guandalini, S. -- Natural history of celiac disease / Kaukinen, K.; Collin, P.; Mäki, M. -- The changing clinical presentation of celiac disease / Lebenthal, E.; Shteyer, E.; Branski, D. -- The global village of celiac disease / Catassi, C.; Yachha, S.K. -- HLA and non-HLA genes in celiac disease / Zhernakova, A.; Wijmenga, C. -- Twins and family contribution to genetics of celiac disease / Greco, L.; Stazi, M.A.; Clerget-Darpoux, F. -- Biochemistry and biological properties of gliadin peptides / Barone, M.V.; Auricchio, S. -- Innate immunity and celiac disease / Meresse, B. ... [et al.] -- Celiac disease: across the threshold of tolerance / Koning, F. -- The role of the intestinal barrier function in the pathogenesis of celiac disease / Fasano, A.; Schulzke, J.D. -- Diagnosis of coeliac disease: open questions / Auricchio, R.; Troncone, R. -- Current guidelines for the diagnosis and treatment of celiac disease / Caicedo, R.A.; Hill, I.D. -- Current therapy / Stern, M. -- Update on the management of refractory coeliac disease / Al-toma, A.; Verbeek, W.H.M.; Mulder, C.J.J. -- The National Institutes of Health consensus conference report / Cohen, M.B.; Barnard, J.A. -- Beyond coeliac disease toxicity: detoxified and non-toxic grains / Gilissen, L.J.W.J.; van der Meer, I.M.; Smulders, M.J.M. -- Oral glutenase therapy for celiac sprue / Ehren, J.; Khosla, C. -- Inhibitors of intestinal barrier dysfunction / Paterson, B.M.; Turner, J.R. -- Development of a vaccine for celiac disease / Anderson, R.P. -- Regulatory T cells in the coeliac intestinal mucosa: a new perspective for treatment? / Gianfrani, C. ... [et al.] -- Strategies for prevention of celiac disease / Hogen Esch, C.E. ... [et al.] -- Towards preventing celiac disease: an epidemiological approach / Ivarsson, A.; Myléus, A.; Wall, S. -- Animal models of celiac disease / Marietta, E.V.; Murray J.A.; David C.S.
- Frontiers in eating and weight regulation 2010Karger"The development of effective preventive and therapeutic measures to control eating and body weight involves basic physiology as well as cognitive and social psychology. The potential of molecular genetics to illuminate brain-behavior relationships became apparent with the discovery of the leptin gene in 1994. At present, molecular methodologies are being integrated with other physiological approaches, resulting in a number of options from which effective therapeutic strategies may evolve. This book highlights this exciting juncture: Fifteen leading experts present brief descriptions of some of the latest developments of the physiology of eating and weight regulation, ranging from endocrine and neural controls to genetics and functional brain imaging. These Frontier chapters are preceded by a general overview that provides requisite background on the physiology of eating as well as a conceptual framework for the Frontier chapters."--Publisher's description.
- This volume represents an up-to-date overview on the major areas of gynecological endocrinology, providing the reader with a complete explanation of female endocrine regulation and metabolism and relevant disorders and treatment. It is published within the International Society of Gynecological Endocrinology (ISGE) Series and is based on the 2013 International School of Gynecological and Reproductive Endocrinology Summer Course. The book covers a very wide range of topics from primary amenorrhea to menopause, from the impact of ovarian surgery on fertility to fertility cryopreservation, from metabolic syndrome and polycystic ovary to premature ovarian failure and from the clinical impact of selective progesterone receptor modulators to the use of progesterone in prevention of premature labor. It will be an important tool for obstetricians and gynecologists, endocrinologists and experts in women's health as well as interested GPs.
- Frontiers in gynecological endocrinology. Volume 2, From basic science to clinical application 2015SpringerThis volume offers an up-to-date overview on the major areas of gynecological endocrinology, presenting the latest advances in adolescent gynecological endocrinology, assisted reproduction, menstrual-related disorders, sexuality and transsexualism, polycystic ovary syndrome, myometrial pathology and adenomyosis, obesity and metabolic syndrome, hormonal contraception, premature ovarian failure and menopause. In each chapter the recent advances deriving from basic science and clinical investigations are related to the practical management of the condition under consideration, taking into account the need for individualized therapies. The book is published within the ISGE Book Series, a joint venture between the International Society of Gynecological Endocrinology and Springer and is based on the 2014 International School of Gynecological and Reproductive Endocrinology Winter Course. It will be an important tool for obstetricians and gynecologists, endocrinologists and experts in women?s health as well as interested GPs.
- Frontiers in viral hepatitis 2003ScienceDirect
- Frontiers of cord blood science 2009Springer
- Print MaterialHistory and nomenclature -- The clinical syndrome of bvFTD -- The clinical syndrome of svPPA -- The clinical syndrome of nfvPPA -- Related disorders : FTD-ALS -- Related disorders : corticobasal degeneration and progressive supranuclear palsy -- A primer of FTLD neuropathology -- FTD genes -- FTD reflections upon psychology and philosophy -- Treatments.
- Frozen section library v. 1-, 2009-Springer
- Frozen section library Endocrine organs 2014SpringerThe Frozen Section Library series provides concise, user-friendly, site specific handbooks that are well illustrated and highlight the pitfalls, artifacts and differential diagnosis issues that arise in the hurried frozen section scenario. Written by expert surgical pathologists, Frozen Section Library: Endocrine Organs presents common and practical problems including follicular adenoma versus follicular carcinoma, papillary thyroid carcinoma versus reactive change and freezing artifact, follicular variant of papillary thyroid carcinoma, and medullary thyroid carcinoma. Anaplastic carcinoma, thyroid lymphoma, resection margin of a pancreatic endocrine tumor, pheochromocytoma within an adrenal gland and extra- adrenal gland, parathyroid tissue versus a thyroid tissue and versus a lymph node are also explored in detail. All chapters are illustrated with color pictures and accompanied legends. As a handbook for practicing pathologists, this volume is an indispensable aid to diagnosis and for avoiding dangers in one of the most challenging situations that pathologists encounter. Rapid consideration of differential diagnoses and how to avoid traps caused by frozen section artifacts are readily accessible. Tables and charts provide guidance for differential diagnosis of various histological patterns.
- Frozen section library. Appendix, colon, and anus 2010SpringerIntraoperative evaluation of colorectal specimens containing cancer -- Intraoperative evaluation for extracolonic disease in colon cancer patients -- Metastases and mimics of colorectal carcinoma -- Non-epithelial tumors of the colorectum -- Frozen section assessment of the colorectum in the pediatric population -- Frozen section evaluation of the appendix -- Frozen section evaluation of anal disease.
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- Harrison's Principles of Internal Medicine
- AAP Red Book Online
- Robbins & Cotran Pathologic Basis of Disease
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