Bookedited by Anthony E. Klon.
Contents:
Solvation methods for protein-ligand docking / Rachelle J. Bienstock
Binding site druggability assessment in fragment-based drug design / Yu Zhou and Niu Huang
Generating "fragment-based virtual library" using pocket similarity search of ligand-receptor complexes / Raed S. Khashan
Virtual fragment preparation for computational fragment- based drug design / Jennifer L. Ludington
Fragment library design : using cheminformatics and expert chemists to fill gaps in existing fragment libraries / Peter S. Kutchukian ... [et al.]
Protocol for fragment hopping / Kevin B. Teuscher and Haitao Ji
Site identification by ligand competitive saturation (SILCS) simulations for fragment-based drug Design / Christina E. Faller ... [et al.]
Computational fragment-based de novo design protocol guided by ligand efficiency indices (LEI) / Álvaro Cortés-Cabrera, Federico Gago, and Antonio Morreale
Scoring functions for fragment-based drug discovery / Jui-Chih Wang and Jung-Hsin Lin
Computational methods for fragment-based ligand design : growing and linking / Rachelle J. Bienstock
Design strategies for computational fragment-based drug design / Zenon D. Konteatis
Protein binding site analysis for drug discovery using a computational fragment-based method / Jennifer L. Ludington
Fragment-based design of kinase inhibitors : a practical guide / Jon A. Erickson
Designing a small molecule erythropoietin mimetic / Frank Guarnieri
Designing an orally available nontoxic p38 inhibitor with a fragment-based strategy / Frank Guarnieri.