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Books

  • Digital
    edited by Craig W. Stevens, Ph.D., Department of Pharmacology and Physiology, College of Osteopathic Medicine, Oklahoma State University-Center for Health Sciences, Tulsa, OK, USA.
    Contents:
    G protein-coupled receptors : research and methods in the post-genomic era / Craig W. Stevens
    Examining the dynamic evolution of G protein-coupled receptors / Claudia Stäubert, Diana Le Duc, and Torsten Schöneberg
    Functional properties of virus-encoded and virus-regulated G protein-coupled receptors / Katja Spiess and Mette M. Rosenkilde
    Discovery and function of the very large G protein-coupled receptor / Perrin C. White and D. Randy McMillan
    Functional evolution of opioid family G protein-coupled receptors / Eyal Vardy, Craig W. Stevens, and Bryan L. Roth
    Investigation of G protein-coupled receptor function and regulation using antisense / Jonathon Willets and Craig Nash
    Signalosome profiling reveals allosteric interactions between G protein-coupled receptors / Katrin Altosaar ... [et al.]
    Use of optogenetic approaches to control intracellular signaling of G protein-coupled receptors / Olivia A. Masseck, Melanie D. Mark, and Stefan Herlitze
    Viral infection for G protein-coupled receptor expression in eukaryotic cells / Antonio Porcellini, Luisa Iacovelli, and Antonio De Blasi
    Using in vitro mutagenesis to characterize structure- function relationships in G protein-coupled receptors / Gregory W. Sawyer and Frederick J. Ehlert
    CRE Luc Mouse model for bioimaging ligand activation of G protein-coupled receptors / H. Gregory Polites and Kyriakos D. Economides
    Inducing conformational changes in G protein-coupled receptors by domain coupling / Hamiyet Unal and Sadashiva S. Karnik
    Rescue of defective G protein-coupled receptor function by intermolecular cooperation / Ashutosh Trehan ... [et al.]
    Design of super-arrestins for gene therapy of diseases associated with excessive signaling of G protein-coupled receptors / Vsevolod V. Gurevich and Eugenia V. Gurevich
    Importance of G protein-coupled receptor genetics in clinical medicine / Ramakrishna Devaki
    Pharmacogenomics of G protein-coupled receptor signaling and other pathways in essential hypertension / Pedro A. Jose ... [et al.]
    Exon sequencing of G protein-coupled receptor genes and perspectives for disease treatment / Angeliki Karamitri and Ralf Jockers
    Gene therapy using G protein-coupled receptors for the treatment of cardiovascular disease / Dario Leosco ... [et al.]
    Novel mechanisms of G protein-coupled receptor oligomer and ion channel Iiteractions in nociception / Ajay S. Yekkirala
    Discovery and characterization of leucine-rich repeat-containing G protein-coupled receptors / Marie-Isabelle Garcia, Valeria Fernandez-Vallone, and Gilbert Vassart
    Role of G protein-coupled receptors in adult neurogenesis / Katie M. Collette, Van A. Doze, and Dianne M. Perez.
    Digital Access Springer 2014
  • Digital
    edited by Duarte Miguel F. Prazeresl, Sofia Aires M. Martins.
    Contents:
    G protein-coupled receptors : an overview of signaling mechanisms and screening assays / Duarte Miguel F. Prazeres and Sofia Aires M. Martins
    Time-resolved FRET strategy to screen GPCR ligand library / Nadia Oueslati [and others]
    Homogeneous fluorescence anisotropy-based assay for characterization of ligand binding dynamics to GPCRs in budded baculoviruses : the case of Cy3B-NDP-α-MSH binding to MC4 receptors / Santa Veiksina . . [and others]
    Construction of recombinant HEK293 cell lines for the expression of the neurotensin receptor NTSR1 / Su Xiao, Joseph Shiloach, and Reinhard Grisshammer
    cAMP assay for GPCR ligand characterization : application of BacMam expression system / Olga Mazina [and others]
    Ca2+ mobilization assays in GPCR drug discovery / Grzegorz Woszczek and Elisabeth Fuerst
    Using constitutive activity to define appropriate high- throughput screening assays for orphan G protein-coupled receptors / Tony Ngo, James L.J. Coleman, and Nicola J. Smith
    Monitoring G protein-coupled receptor activation using the protein fragment complementation technique split TEV / Michael C. Wehr, Sabrina Galinski, and Moritz J. Rossner
    Quantifying GPCR iternalization : a focus on the kisspeptin receptor / Macarena Pampillo and Andy V. Babwah
    GPCR oligomerization analysis by means of BRET and dFRAP / Francisco Ciruela and Víctor Fernández-Dueñas
    Use of imageJ to recover information from individual cells in a G protein-coupled receptor assay / João R.C. Trabuco, Sofia Aires M. Martins, and Duarte Miguel F. Prazeres
    Methods to immobilize GPCR on the surface of SPR sensors / Laura Martínez-Muñoz [and others]
    Olfactory receptor screening assay using nanovesicle- immobilized carbon nanotube transistor / Jong Hyun Lim [and others]
    Label-free biosensor assays in GPCR screening / Manuel Grundmann and Evi Kostenis
    Multidimensional GPCR profiling and screening using impedance-based label-free and real-time assay / Ning Ke [and others]
    Label-free functional selectivity assays / Ann M. Ferrie [and others]
    Measurement of surface-mediated Ca2+ transients on the single-cell level in a microfluidic lab-on-a-chip environment / Michael Kirschbaum, Magnus S. Jaeger, and Claus Duschl
    Cell-based assays and animal models for GPCR drug screening / Hideo Takakura [and others]
    Computer-aided design of GPCR ligands / Hugo Gutiérrez-de-Terán [and others].
    Digital Access Springer 2015
  • Digital/Print
    Marta Filizola, editor.
    Summary: G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses. Since GPCRs are natural targets for approximately 40% of all modern medicines, it is not surprising that they have been the subject of intense research. Notwithstanding the amount of data generated over the years, discovering ligands of these receptors with optimal therapeutic properties is not straightforward and has certainly been hampered for years by the lack of high-resolution structural information about these receptors.--Back cover.

    Contents:
    Pt. I. Progress in structural modeling of GPCRs
    The GPCR crystallography boom: providing an invaluable source of structural information and expanding the scope of homology modeling
    Modeling of G protein-coupled receptors using crystal structures: from monomers to signaling complexes
    Pt. II. GPCRs in motion: insights from simulations
    Structure and dynamics of G-protein coupled receptors
    How the dynamic properties and functional mechanisms of GPCRs are modulated by their coupling to the membrane environment
    Coarse-grained molecular dynamics provides insights into the interactions of lipids and cholesterol with rhodopsin
    Beyond standard molecular dynamics: investigating the molecular mechanisms of G protein-coupled receptors with enhanced molecular dynamics methods
    Pt. III. GPCR-focused design and mathematical modeling
    From three-dimensional GPCR structure to rational ligand discovery
    Mathematical modeling of G protein-coupled receptor function: what can we learn from empirical and mechanistic models?
    Pt. IV. Bioinformatics tools and resources for GPCRs
    GPCR & company: databases and servers for GPCRs and interacting partners
    Bioinformatics tools for predicting GPCR gene functions.
    Digital Access Springer 2014
  • Digital
    edited by Arun K. Shukla.
    Digital Access
    Provider
    Version
    ScienceDirect
    ScienceDirect
  • Digital
    edited by Marta Filizola
    Contents:
    Purification of stabilized GPCRs for structural and biophysical analyses / James C. Errey ... [et al.]
    Purification and crystallization of a thermostabilized agonist-bound conformation of the human adenosine A2A receptor / Christopher G. Tate and Guillaume Lebon
    2D projection analysis of GPCR complexes by negative stain electron microscopy / Alys Peisley and Georgios Skiniotis
    Nuts and bolts of CF3 and CH3 NMR towards the understanding of conformational exchange of GPCRs / R. Scott Prosser and Tae Hun Kim
    Single-molecule fluorescence microscopy for the analysis of fast receptor dynamics / Julia Wagner ... [et al.]
    Quantitative multi-color detection strategies for bioorthogonally labeled GPCRs / Minyoung Park ... [et al.]
    Approaches to characterize and quantify oligomerization of GPCRs / Sara Marsango, María José Varela, and Graeme Milligan
    Monitoring G protein activation in cells with BRET / Ikuo Masuho, Kirill A. Martemyanov, and Nevin A. Lambert
    Use of fluorescence indicators in receptor ligands / Kaleeckal G. Harikumar and Laurence J. Miller
    Detection and quantification of intracellular signaling using FRET-based biosensors and high content imaging / Michelle L. Halls ... [et al.]
    Measurement of receptor signaling bias / Terry Kenakin
    Approaches to assess functional selectivity in GPCRs : evaluating G protein signaling in an endogenous environment / Laura M. Bohn, Lei Zhou, and Jo-Hao Ho
    Bioluminescence resonance energy transfer approaches to discover bias in GPCR signaling / Elizabeth K. M. Johnstone and Kevin D. G. Pfleger
    Virus-mediated expression of DREADDs for in vivo metabolic studies / Mario Rossi ... [et al.]
    High-throughput screening for allosteric modulators of GPCRs / Robert L. Bertekap Jr. ... [et al.]
    Radioligand binding assay for an exon 11-associated mu opioid receptor target / Gina F. Marrone, Susruta Majumdar, and Gavril W. Pasternak
    Docking and virtual screening strategies for GPCR drug discovery / Thijs Beuming ... [et al.]
    Dynamic process of drug-GPCR binding at either orthosteric or allosteric sites evaluated by metadynamics / Sebastian Schneider, Davide Provasi, and Marta Filizola
    Experiment-guided molecular modeling of protein-protein complexes involving GPCRs / Irina Kufareva, Tracy M. Handel, and Ruben Abagyan
    Interaction fingerprints and their applications to identify hot spots / Andrés F. Marmolejo ... [et al.].
    Digital Access Springer 2015
  • Digital
    edited by Holly Crisp, Glen O. Gabbard.
    Summary: "The second edition of Gabbard's Textbook of Psychotherapeutic Treatments provides up-to-date information on psychotherapies, including psychodynamic therapies, mentalization-based treatment, transference-focused therapy, cognitive-behavioral therapy, supportive psychotherapy, and interpersonal psychotherapy. The textbook also reflects social changes that have had profound impacts on how therapists practice, including the advancement of LGBTQ rights, calls for racial and social justice, and the COVID-19 pandemic"-- Provided by publisher.
    Digital Access PsychiatryOnline 2023
  • Digital
    [edited by] Glen O. Gabbard, M. D., Professor of Psychiatry, State University of New York-Upstate Medical University, Syracuse, New York, Clinical Professor of Psychiatry, Baylor College of Medicine, Houston, Texas, Private Practice, The Gabbard Center, Houston, Texas.
    Contents:
    Intellectual disability (intellectual developmental disorder)
    Communication disorders
    Autism spectrum disorder
    Attention-deficit/hyperactivity disorder
    Specific learning disorder
    Tic disorders
    Elimination disorders
    Early-stage schizophrenia
    Toward a dimensional understanding of psychosis and its treatment
    Psychosocial treatments for chronic psychosis
    Pharmacological treatment of psychosis
    Psychotherapy of mood disorders
    Acute and maintenance treatment of bipolar and related disorders
    Pharmacological and somatic treatments for major depressive disorder
    Brain stimulation treatments for mood disorders
    Panic disorder
    Separation anxiety disorder
    Social anxiety disorder (social phobia)
    Generalized anxiety disorder
    Specific phobia
    Obsessive-compulsive disorder
    Body dysmorphic disorder
    Hoarding disorder, trichotillomania (hair-pulling disorder), and excoriation (skin-picking) disorder
    Dissociative identity disorder
    Depersonalization/derealization disorder
    Dissociative amnesia
    Posttraumatic stress disorder
    Acute stress disorder
    Adjustment disorders
    Evidence-based psychological treatments for eating disorders
    Pharmacological treatment of eating disorders
    Intensive treatment for eating disorders
    Primary care and consultation-liaison interventions for somatic symptom and related disorders
    Pharmacological interventions for psychosomatic disorders
    Intensive interventions for somatic symptom disorders
    Sleep-wake disorders
    Sexual dysfunctions
    Paraphilias and paraphilic disorders
    Gender dysphoria
    Oppositional defiant disorder
    Intermittent explosive disorder
    Conduct disorder
    With limited prosocial emotions specifier for conduct disorder
    Pyromania
    Kleptomania
    Alcohol-related disorders
    Sedative-, hypnotic-, or anxiolytic-related disorders
    Opioid-related disorders: opioid detoxification
    Opioid-related disorders: antagonist treatment
    Opioid-related disorders: agonist maintenance treatment
    Hallucinogen-related disorders
    Cannabis-related disorders
    Club drug addiciton
    Stimulant-related disorders
    Nicotine-related disorders
    Individual therapy for substance use disorders
    Cognitive, behavioral, and motivational therapies for substance use disorders
    Group therapy for substance use disorders
    Family therapy in substance abuse treatment
    Network therapy for substance use disorders
    Pain and addiction
    Gambling disorder
    Delirium
    Neurocognitive disorder due to Alzheimer's disease
    Frontotemporal neurocognitive disorder
    Vascular neurocognitive disorder
    Neurocognitive disorder due to Parkinson's disease
    Paranoid, schizotypal, and schizoid personality disorders
    Antisocial personality disorder
    Borderline personality disorder
    Histrionic personality disorder
    Narcissistic personality disorder
    Cluster C personality disorders: avoidant, dependent, and obsessive-compulsive.
    Digital Access PsychiatryOnline 2014
  • Digital
    [edited by] Mark B. Landon [and 8 others].
    Summary: "This book focuses solely on obstetrics with only the most important, clinically relevant points included, making it a quick and reliable way to find answers, confirm clinical decisions, or guide initial assessments. Includes key points at the beginning of each chapter, specially selected figures and tables, and a glossary of terms for efficient study and fast reference. Features clinically important information throughout." -- Publisher.

    Contents:
    Part I: Physiology
    Part II: Prenatal care
    Part III: Intrapartum care
    Part IV: Postpartum care
    Part V: Complicated pregnancy
    Part VI: Pregnancy and coexisting disease
    Part VII: Legal and ethical issues in perinatology
    Digital Access ClinicalKey 2019
  • Digital
    M. Raza Zaidi, Dan A. Liebermann, editors.
    Summary: This second edition is fully updated throughout and covers the emerging evidence that indicates that the Gadd45 family of proteins plays a unique and critical role as sensors of stress, including genotoxic, physiological, and oncogenic stress. It sheds light on the complex cellular stress response, encompassing myriad molecular pathways with a plethora of regulators and effectors. The GADD45 stress response genes encode small (18 kd) nuclear/cytoplasmic proteins. These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. Despite marked similarities, Gadd45 genes are regulated differentially and exhibit functional diversity. Gadd45 proteins respond to physiological and oncogenic stress, and are implicated in cell cycle arrest, DNA demethylation and repair, apoptosis, cell survival, genomic stability, and inflammation. The purpose of this book is to provide a comprehensive overview of the unique global role that Gadd45 proteins play as stress sensors and the molecular pathways involved.

    Contents:
    GADD45 in Stress Signaling, Cell Cycle Control, and Apoptosis
    GADD45 in Development and Cancer
    GADD45 in Normal Hematopoiesis and Leukemia
    GADD45 in DNA Methylation and DNA Repair
    GADD45 Proteins in Immunity
    GADD45 in Liver Function and Cancer
    GADD45 in Pre-Eclampsia
    GADD45 in Senescence
    GADD45 in Neuronal Development, Function, and Injury
    Index.
    Digital Access Springer 2022
  • Digital
    Betty L. Gahart, Adrienne R. Nazareno, Meghan Q. Ortega.
    Digital Access
    Provider
    Version
    ClinicalKey Nursing
    ClinicalKey
  • Digital
    edited by Sean R. Stowell, Richard D. Cummings.
    Contents:
    Evolving mechanistic insights into galectin functions / Connie M. Arthur [and three others]
    Cloning, expression, and purification of galectins for in vitro studies / Paul A. Poland, Carol L. Kinlough, and Rebecca P. Hughey
    Alkylation of galectin-1 with iodoacetamide and mass spectrometric mapping of the sites of incorporation / Sean R. Stowell [and three others]
    Evaluation of galectin binding by frontal affinity chromatography (FAC) / Jun Iwaki and Jun Hirabayashi
    Probing lectin-mucin interactions by isothermal titration microcalorimetry / Tarun K. Dam and C. Fred Brewer
    Examination of whole cell galectin binding by solid phase and flow cytometric analysis / Anne Leppänen, Connie M. Arthur, Sean R. Stowell, and Richard D. Cummings
    Evaluation of galectin binding by surface plasmon resonance / Padmaja Mehta-D'souza
    Examining galectin binding specificity using glycan microarrays / Connie M. Arthur [and seven others]
    Methods for assessing the effects of galectins on leukocyte trafficking / Beatrice R. Gittens, Rachael D. Wright, and Dianne Cooper
    Examination of the role of galectins in plasma cell differentiation / Chih-Ming Tsai and Kuo-I Lin
    Examination of galectin-induced lattice formation on early B-cell development / Stéphane J.C. Mancini [and five others]
    Detection of phosphatidylserine exposure on leukocytes following treatment with human galectins / Connie M. Arthur [and five others]
    Examination of galectins in phagocytosis / Huan-Yuan Chen [and four others]
    Assessing the roles of galectins in regulating dendritic cell migration through extracellular matrix and across lymphatic endothelial cells / Sandra Thiemann, Jeanette H. Man, and Linda G. Baum
    Examination of the role of galectins in intestinal inflammation / Atsushi Nishida, Cindy W. Lau, and Atsushi Mizoguchi
    Study of galectins in tumor immunity : strategies and methods / Juan P. Cerliani [and seven others]
    Galectins in the regulation of platelet biology / Maria A. Romaniuk, Gabriel A. Rabinovich, and Mirta Schattner
    Examination of the role of galectins and galectin inhibitors in endothelial cell biology / Iris A. E. Schulkens [and four others]
    Regulation of galectins by hypoxia and their relevance in angiogenesis : strategies and methods / Mariana Salatino [and ten others]
    Examination of the role of galectins during in vivo angiogenesis using the chick chorioallantoic membrane assay / Esther A. Kleibeuker [and four others]
    Examination of the role of galectins in cell migration and re-epithelialization of wounds / Zhiyi Cao [and three others]
    Manipulating galectin expression in Zebrafish (Danio rerio) / Chiguang Feng [and seven others]
    Examination of galectin localization using confocal microscopy / Daniel Giuliano Cerri [and six others]
    Examination of the regulation of galectin-3 expression in cancer / Hafiz Ahmed and Gargi Bandyopadhyaya
    Evaluation of the role of galectins in parasite immunity / Sarah Preston [and four others]
    Effect of galectins on viral transmission / Michel Ouellet [and three others]
    Evaluation of the bactericidal activity of galectins / Connie M. Arthur, Richard D. Cummings, and Sean R. Stowell
    Examination of the role of galectins in pre-mRNA splicing / Ronald J. Patterson [and three others]
    Analysis of the intracellular role of galectins in cell growth and apoptosis / Daniel K. Hsu [and three others]
    Nucleocytoplasmic shuttling of galectin-3 / Eric J. Arnoys, Cheri M. Ackerman, and John L. Wang.
    Digital Access Springer 2015
  • Digital
    Vijay Kumar Shukla, Manoj Pandey, Ruhi Dixit, editors.
    Summary: The book discusses the recent progress in understanding the therapeutic targets for gallbladder cancer to provide opportunities for research and for developing innovative strategies that may enhance the benefit of conventional chemotherapy. The book focuses on identifying candidate molecules and the overall status of the targeted therapies available for gallbladder cancer, as there is an urgent need to discover new molecular targets that can guide the emergence of new treatment strategies to improve patient outcomes and act as biomarkers for the early detection of diseases. Recently, new treatment therapeutics targets for gallbladder cancer patients have been identified and the field is evolving rapidly. The book is relevant for the clinical researcher, surgeon, scientist and academician.

    Contents:
    Gallbladder Cancer: Current treatment options and therapeutics
    Surgical Management of Gallbladder Cancer Patients
    Conventional therapy in Gallbladder Cancer
    Adjuvant Therapy following Surgical Treatment of Gallbladder Cancer
    Incidental gallbladder cancer: the role of routine versus selective histopathological examination of gallbladder specimens after cholecystectomy
    Minimally Invasive Surgery for Management of Gallbladder Cancer
    Thickwalled Gallbladder: Differential diagnosis and surgical approach to a thickened gallbladder
    Management of incidentally detected gallbladder cancer after cholecystectomy
    Adjuvant treatment in radically resected gallbladder cancer
    A look at emerging therapeutic targets for gallbladder cancer: a multi-omics approach
    MicroRNA and their role in Carcinoma Gallbladder
    Gallbladder cancer: Epigenetic landscape, Targeted therapy and Prospect of Epitherapy
    Targeted treatment of Gallbladder cancer
    Molecular pathways in Gallbladder cancer as potential therapeutic target
    Targeted Therapy: Molecular Pathology and Targets of Gallbladder Cancer
    Targeted Therapies in Gallbladder Cancer: Current Status and Future Perspectives
    Integrative omics - the roadmap for gallbladder biomarkers identification
    Anti-EGFR Therapy in Gall Bladder Cancer.
    Digital Access Springer 2023
  • Digital
    editors, Andreas Heinz, Nina Romanczuk-Seiferth and Marc N. Potenza.
    Digital Access Springer 2019
  • Digital
    edited by Jon E. Grant, Marc N. Potenza.
    Summary: "Seventeen years since the first edition and eight years since DSM-5 reclassified "pathological gambling," Gambling Disorder: A Clinical Guide to Treatment is here to provide clinicians with the latest thinking about gambling disorder. It is an exciting moment in the history of gambling research, with scholarly inquiry into the epidemiology, etiology, neurobiology, and treatment of this disorder growing by leaps and bounds. However, many clinicians remain unaware of the disorder's symptoms, though common, and are uninformed about available treatments, many developed quite recently. Acting on this knowledge, the editors set out to compile a guide that would equip clinicians to recognize patients exhibiting signs of the disorder, competently assess them, and work to identify effective treatment options. In addition, the book explores different ways the disorder may manifest across genders and among older and younger patients, forensic issues, and the relatively new area of study, online gambling and gambling-gaming convergence. Not so much a revision as a reconceptualization, Gambling Disorder: A Clinical Guide to Treatment brings a new cast of contributors, a totally restructured text, and the research and clinical wisdom amassed over the past decade and a half to bear on this critically important, yet often overlooked, disorder"-- Provided by publisher.

    Contents:
    Epidemiology : the good, the bad, and the ugly / Nathan D.L. Smith, Linda B. Cottler
    Clinical characteristics / Donald W. Black
    Older adults / Georgina M. Gross, Rani A. Hoff
    Gender differences / Jon E. Grant, Samuel R. Chamberlain
    Online gambling and gambling-gaming convergence / Daniel L. King, Sally M. Gainsbury, Paul H. Delfabbro
    Legal and forensic aspects / Austin W. Blum, Jon E. Grant
    Cognitive and behavioral underpinnings / Elijah Otis, Igor Yakovenko, Sherry H. Stewart
    Neurobiology / Luis C. Farhat, Marc N. Potenza
    Screening and assessment instruments / Randy Stinchfield
    Understanding youth gambling problems : prevention and treatment strategies / Jeffrey L. Derevensky, Lynette Gilbeau
    Psychosocial treatments / Brad W. Brazeau, David C. Hodgins
    Pharmacological treatments / Jon E. Grant, Samuel R. Chamberlain.
    Digital Access PsychiatryOnline 2022
  • Digital
    He-Feng Huang, Jian-Zhong Sheng, editors.
    Summary: The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians.

    Contents:
    Physiology of gametogenesis
    Physiology of embryo development
    Diabetes originated from embryo-fetal development
    Cardiovascular disease originated from embryo-fetal development
    Tumor originated from embryo-fetal development
    Obesity originated from embryo-fetal development
    Infertility originated from embryo-fetal development
    Mental health originated from embryo-fetal development
    Assisted reproductive technology (ART) and embryo-fetal origin of diseases
    Adverse intrauterine environment and embryo-fetal origin of diseases.
    Digital Access Springer 2014
  • Print
    edited by Mario Biagioli and Alexandra Lippman.
    Contents:
    Gaming metrics before the game : citation and the bureaucratic virtuoso / Alex Csiszar
    The transformation of the scientific paper : from knowledge to accounting unit / Yves Gingras
    Playing and being played by the research impact game / Michael Power
    The mismeasurement of quality and impact / Paul Wouters
    Taking Goodhart's law meta : gaming, meta-gaming, and hacking academic performance metrics / James Griesemer
    Global university rankings' impacts and applications / Barbara M. Kehm
    Predatory publishing and the imperative of international productivity : feeding off and feeding up the dominant / Sarah de Rijcke & Tereza StÃckelová
    Pressures to publish : what effects do we see? / Daniele Fanelli
    Ghost-managing and gaming pharmaceutical knowledge / Sergio Sismondo
    Retraction watch : what we've learned, and how metrics play a role / Ivan Oransky
    PubPeer : scientific assessment without metrics / Boris Barbour & Brandon Stell
    The Voinnet affair : testing the norms of scientific image management / Catherine Guaspare & Emmanuel Didier
    Crossing the line : pseudonyms & snark in post-publication peer review / Paul S. Brookes
    Ike Antkare, his publications and those of his disciples / Ike Antkare
    Fake scientists on editorial boards can significantly enhance the visibility of junk journals / Burkhard Morgenstern
    Altmetrics gaming : beast within or without? / Jennifer Lin
    Why we could stop worrying about gaming metrics if we stopped using journal articles for publishing scientific research / Elizabeth Wager
    Making people and influencing friends : citation networks and the appearance of significance / Finn Brunton
    Crack open the make-believe : counterfeit, publication ethics and the Global South / Marie-André Jacob
    Fake archives : the search for openness in scholarly communication platforms / Alessandro Delfanti
    Humor, hoaxes and software : the carnivalesque in the search for academic misconduct / Alexandra Lippman.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    Z286.S37 G36 2020
    1
  • Digital
    Mikhail F. Chernov, Motohiro Hayashi, Clark C. Chen, Ian E. McCutcheon, editors.
    Summary: The articles in this volume cover the various radiosurgical techniques used to treat benign and malignant intracranial tumors, cavernous malformations, and functional disorders, as well as a wide array of specific details on medical physics, neuroimaging, and anesthetic support. Particular emphasis is put on the optimal combination of microneurosurgery and radiosurgery for attaining the best functional results in patients with vestibular schwannomas, craniopharyngiomas, and pituitary adenomas, and on the most effective methods of treatment planning and radiation dosimetry in cases of metastatic brain tumors. The highlighted clinical aspects include indications for radiosurgery and the prediction of patients prognosis, along with analysis of outcomes in comparison with results achieved by other modalities in the context of multifaceted therapeutic strategies. In addition, possible options for applying advanced treatment using such modern devices as Leksell Gamma Knife PerfexionTM and IconTM are presented in depth. This information will interest both radiosurgical practitioners and neurosurgeons, and help them to provide optimal care and to achieve the greatest benefit of their patients.
    Digital Access Springer 2021
  • Print
    Section editor: A. G. Karczmar.
    Contents:

    v. 1. Muscarinic and nicotinic stimulant actions at autonomic ganglia, by R. L. Volle.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    U323 .K18 1966
    1
  • Digital
    Cheorl-Ho Kim.
    Summary: This book presents the latest knowledge and the most recent research results in the field of ganglioside biochemistry. The early chapters cover all relevant background on sialic acids and their biosynthesis, on N-glycolylneuraminic acid (Neu5Gc), which cannot be synthesized by humans, and on general aspects of ganglioside research. Ganglioside adsorption, disorders of ganglioside degradation, and the regulation of gangliosides are thoroughly discussed. A major focus of the book is the role of gangliosides in cancer. Here, the discussion encompasses, for example, the biological importance, antigenicity, and immunological actions of tumor-associated gangliosides (TAGs), the significance of different glycolipids and gangliosides as TAGs, and emerging anti-cancer vaccine strategies. The ability of sialic acids and TAGs of tumor cells to escape immunosurveillance and immunoediting also receives detailed attention. The significance of sialic acids in regulation of the complement system is explained, and the closing chapter focuses especially on the role of sialyl T antigen in cancer. The book will be of value for all who are interested in functional glycobiology and glycomic studies.

    Contents:
    Intro
    Preface
    Carbohydrates: The Third Life Chain
    Contents
    Chapter 1: Glycosylation
    1.1 General Aspect of Glycosylation
    1.2 Classification of Protein Glycosylation and Posttranslational Modification
    1.3 Glycosyltransferases
    1.3.1 ABO Blood Type Model of Glycosyltransferases and Historical View
    1.3.2 Enzyme Properties of Glycosyltransferases
    References
    Chapter 2: N-Glycan and O-Glycan Glycosylation in Eukaryotes
    2.1 Dolichol-Linked Oligosaccharide (DLO) Biosynthesis for Initial Supplies in N-Glycans
    2.2 N-Glycan Glycosylation in ER 3.5 Sulfotransferases for Modification of Carbohydrates
    References
    Chapter 4: Congenital Disorders of Glycosylation (CDG) of N-Glycoprotein
    References
    Chapter 5: Neuraminic Acids/Sialic Acids (N-acetyl- and N-glycolylneuraminic Acid)
    5.1 Sialic Acids for Differentiation Between Animal and Plant Kingdom
    5.2 Outlined Biological Function of Sialic Acids
    5.3 Structural Diversity of Sialic Acid Species
    5.4 Emerging SA-Containing Glycosphingolipids and Evolutional Occurrence of Methyl-SAs from Deuterosome Echinoderms During the...
    References 7.6 Human Serum IgG Antibodies Kill Cultured Primary Leukemia Cells Fed with NeuGc Species
    7.7 DCs Behavior During the Acquisition of NeuGc
    7.8 The Functions of SA Residue and SA-Linked Carbohydrate Chain
    References
    Chapter 8: Gangliosides
    8.1 General Aspects in Current Gangliobiology
    8.1.1 The Immune Suppression and Escape Capacity of Cancer Gangliosides
    8.1.2 Regulation of Growth Factor (GF)-GF Receptor (GFR)-Mediated Functions by Gangliosides in the Tumor Microenvironment
    8.1.3 Gangliosides Inhibit Cell Cycle and Signaling Chapter 6: Biosynthesis of Sialic Acid
    6.1 Hexosamine Pathway and CMP-SA Biosynthesis
    6.2 Enzyme Properties of GNE, GFPT, and PGM3 and Utilization of Synthesized SA
    References
    Chapter 7: Neu5Gc (N-Glycolylneuraminic Acid)
    7.1 Enzymatic Synthesis of Neu5Gc
    7.2 Expression of Neu5Gc-Forming CMAH in Animals, But Not Humans
    7.3 Biological Functions of the NeuGc in Normal System and Xeno-System
    7.4 Tumor Immunogenicity of NeuGc Incorporation
    7.5 Evolutionary Defense Mechanism of Neu5Gc Biosynthesis in Parasite Infection
    Digital Access Springer 2020
  • Print
    Summary: Consists of the proceedings of international conference and symposia.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Periodicals (Downstairs)
    39
  • Digital
    edited by Zhibin Lin, Baoxue Yang.
    Summary: "This book presents a state-of-the-art report on recent advances concerning Ganoderma and where the field is going. Although some older work is also cited, the main focus is on advances made over the past 20 years in the research history, classification, chemical components and industry of Ganoderma. Ganoderma lucidum (Lingzhi) has been used as a traditional medicine in Asian countries to maintain health and to treat diseases for more than two thousand years. Recently, its value has been demonstrated in preventing and treating certain diseases, such as tumors, liver disorders, renal injury, hypercholesterolemia, obesity, cerebral ischemia reperfusion, bronchitis etc. In addition, laboratory and clinical studies have confirmed that the chemical components of Ganoderma, such as Ganoderma lucidum polysaccharide peptides and triterpenes isolated from the fruiting body of Ganoderma lucidum, produce diverse pharmacological effects. Ganoderma and its components play an important part in antioxidant stress, radical-scavenging, immunomodulation, and intracellular signaling regulation, and accordingly warrant further study. This book systematically reviews the latest advances in our understanding of Ganoderma's basic knowledge, history of modern research, species, cultivation, components, spore polysaccharide and industry of Ganoderma, and offers researchers and graduate students valuable new insights into the development and clinical applications of Ganoderma and related products"--Publisher's description.

    Contents:
    Ganoderma (Lingzhi) in traditional Chinese medicine and Chinese culture / Zhibin Lin
    Classification, biological characteristics and cultivations of Ganoderma / Zhuo Du, Cai-Hong Dong, Ke Wang, Yi-Jian Yao
    Chemical components of Ganoderma / Ting Gong, Renyi Yan, Jie Kang, Ruoyun Chen
    Polysaccharide of Ganoderma and its bioactivities / Jingsong Zhang, Yanfang Liu, Qingjiu Tang, Shuai Zhou, Jie Feng, Hongyu Chen
    Quantitative analysis of components in Ganoderma/ Ruoyun Chen, Jie Kang
    Researches and application of Ganoderma spores powder / Jianhua Xu, Peng Li
    Development and innovation of Ganoderma industry and products in China / Zhenhao Li, Jianlong Zhou, Zhibin Lin
    Digital Access Springer 2019
  • Digital
    Zhibin Lin, Baoxue Yang, editors.
    Summary: This book presents a state-of-the-art report on recent advances concerning Ganoderma and where the field is going. Although some older work is also cited, the main focus is on advances made over the past 20 years in the pharmacology and clinical applications of Ganoderma. Ganoderma lucidum (Lingzhi) has been used as a traditional medicine in Asian countries to maintain health and to treat diseases for more than two thousand years. Recently, its value has been demonstrated in preventing and treating certain diseases, such as tumors, liver disorders, renal injury, hypercholesterolemia, obesity, cerebral ischemia reperfusion, bronchitis etc. In addition, laboratory and clinical studies have confirmed that the chemical components of Ganoderma, such as Ganoderma lucidum polysaccharide peptides and triterpenes isolated from the fruiting body of Ganoderma lucidum, produce diverse pharmacological effects. Ganoderma and its components play an important part in antioxidant stress, radical-scavenging, immunomodulation, and intracellular signaling regulation, and accordingly warrant further study. This book systematically reviews the latest advances in our understanding of pharmacology and clinical applications of Ganoderma, and offers researchers and graduate students valuable new insights into the pharmacology and clinical applications of Ganoderma and related products.

    Contents:
    Immunomodulating Effect of Ganoderma (Lingzhi) and Possible Mechanism
    Antitumor Effect of Ganoderma(Lingzhi) Mediated by Immunological Mechanism and Its Clinical Application
    Cellular and Molecular Mechanism of Ganoderma (Lingzhi) against Tumor
    Protective Effect of Ganoderma on Radiation and Chemotherapy
    Neuropharmacological Effect and Clinical Applications of Ganoderma
    Preventive and Therapeutic Effect of Ganoderma on Brain Injury
    Protective Effect of Ganoderma Lucidum on Cardiovascular System
    Preventive and Therapeutic Effect of Ganoderma on Diabetes
    Preventive and Therapeutic Effect of Ganoderma on Liver Injury
    Preventive and Therapeutic Effect of Ganoderma Lucidum on Renal Diseases and Clinical Applications
    Anti-osteoporosis Effect of Ganoderma (Lingzhi) by Inhibition of Osteoclastogenesis
    Anti-oxidative and Free Radical Scavenging Activity of Ganoderma (Lingzhi)
    Anti-aging Effect of Ganoderma with Health and Fitness
    Preventive and Therapeutic Effect of Ganoderma on Skin Diseases and Care. .
    Digital Access Springer 2019
  • Print
    Susan M. Barman, Kim E. Barrett, Heddwen L. Brooks, Jason X.­-J. Yuan.
    Summary: " ... our primary goal has been to streamline the text of the "parent" volume, Ganong's Review of Medical Physiology for ease of review, retaining only the most high-yield concepts and illustrations. We have updated the content where needed, aligned the self-study questions with the order in which concepts are presented in the text, and expanded the explanations of why the answer to these questions is in fact the best one and why the distractors are wrong, further enhancing conceptual understanding of physiology rather than simply reinforcing rote memorization. "--Preface.

    Contents:
    General Principles & Energy Production in Medical Physiology
    Overview of Cellular Physiology in Medical Physiology
    Immunity, Infection, & Inflammation
    Excitable Tissue: Nerve
    Excitable Tissue: Muscle
    Synaptic & Junctional Transmission
    Neurotransmitters & Neuromodulators
    Somatosensory Neurotransmission: Touch, Pain, & Temperature
    Smell & Taste
    VISION
    Hearing & Equilibrium
    Reflex & Voluntary Control of Posture & Movement
    Autonomic Nervous System
    Electrical Activity of the Brain, Sleep-Wake States, & Circadian Rhythms
    Learning, Memory, Language, & Speech
    Basic Concepts of Endocrine Regulation
    Hypothalamic Regulation of Hormonal Functions
    The Pituitary Gland
    The Adrenal Medulla & Adrenal Cortex
    The Thyroid Gland
    Hormonal Control of Calcium & Phosphate Metabolism & the Physiology of Bone
    Reproductive Development & Function of the Female Reproductive System
    Function of the Male Reproductive System
    Endocrine Functions of the Pancreas & Regulation of Carbohydrate Metabolism
    Overview of Gastrointestinal Function & Regulation
    Digestion, Absorption, & Nutritional Principles
    Gastrointestinal Motility
    Transport & Metabolic Functions of the Liver
    Origin of the Heartbeat & the Electrical Activity of the Heart
    The Heart as a Pump
    Blood as a Circulatory Fluid & the Dynamics of Blood & Lymph Flow
    Cardiovascular Regulatory Mechanisms
    Circulation Through Special Regions
    Introduction to Pulmonary Structure & Mechanics
    Gas Transport & pH
    Regulation of Respiration
    Renal Function & Micturition
    Regulation of Extracellular Fluid Composition & Volume
    Acidification of the Urine & Bicarbonate Excretion.
    Digital Access
    Provider
    Version
    AccessMedicine
    2024 Study Tools
    AccessMedicine
    2024 Fulltext
  • Digital
    Kim E. Barrett, Susan M. Barman, Scott Boitano, Jane F. Reckelhoff.
    Contents:
    Section I. Cellular & molecular basis for medical physiology : General principles & energy production in medical physiology ; Overview of cellular physiology in medical physiology ; Immunity, infection, & inflammation ; Excitable tissue: nerve ; Excitable tissue: muscle ; Synaptic & junctional transmission ; Neurotransmitters & neuromodulators
    Section II. Central & peripheral neurophysiology : Somatosensory neurotransmission: touch, pain, & temperature ; Vision ; Hearing & equilibrium ; Smell & taste ; Reflex & voluntary control of posture & movement ; Autonomic nervous system ; Electrical activity of the brain, sleep--wake states, & circadian rhythms ; Learning, memory, language, & speech
    Section III. Endocrine & reproductive physiology : Basic concepts of endocrine regulation ; Hypothalamic regulation of hormonal functions ; The pituitary gland ; The thyroid gland ; The adrenal medulla & adrenal cortex ; Hormonal control of calcium & phosphate metabolism & the physiology of bone ; Reproductive development & function of the female reproductive system ; Function of the male reproductive system ; Endocrine functions of the pancreas & regulation of carbohydrate metabolism
    Section IV. Gastrointestinal physiology : Overview of gastrointestinal function & regulation ; Digestion, absorption, & nutritional principles ; Gastrointestinal motility ; Transport & metabolic functions of the liver
    Section V. Cardiovascular physiology : Origin of the heartbeat & the electrical activity of the heart ; The heart as a pump ; Blood as a circulatory fluid & the dynamics of blood & lymph flow ; Cardiovascular regulatory mechanisms ; Circulation through special regions
    Section VI. Respiratory physiology : Introduction to pulmonary structure & mechanics ; Gas transport & pH ; Regulation of respiration
    Section VII. Renal physiology : Renal function & micturition ; Regulation of extracellular fluid composition & volume ; Acidification of the urine & bicarbonate excretion.
    Digital Access AccessMedicine 2018
  • Digital/Print
    Barrett, Kim E.; Ganong, William F.
    Digital Access
    Provider
    Version
    AccessPharmacy
    AccessMedicine
    AccessMedicine
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    QP34.5 .G198
    17
  • Digital
    George H. Pink, Paula H. Song.
    Digital Access R2Library 2020
    Limited to 1 simultaneous user
  • Digital
    Leslie P. Gartner, Lisa M.J. Lee.
    Summary: "This histology atlas and text provides medical, dental, allied health, and biology students with an outstanding collection of histology images for all of the major tissue classes and body systems. This is a concise approach with relevant text and consistent format presentation of photomicrograph plates. It features a full-color art program comprising high-quality photomicrographs, scanning electron micrographs, and supporting illustrations. Didactic features in each chapter includes: Chapter Outline, Histophysiology, Clinical Considerations, Overview Diagrams, Atlas Plates, Review Plates, and Summary of Histologic Organization. Clinical-vignette style board-review questions have been added to the new edition as well as standard review questions."-- Provided by publisher

    Contents:
    Introduction to Histologic Techniques
    Cell Biology
    Epithelium and Glands
    Connective Tissue
    Cartilage and Bone
    Blood and Hemopoiesis
    Muscle
    Nervous Tissue
    Circulatory System
    Lymphoid (Immune) System
    Endocrine System
    Integument
    Respiratory System
    Digestive System I
    Digestive System II
    Digestive System III
    Urinary System
    Female Reproductive System
    Male Reproductive System
    Special Sense - Appendix A: Tissues that Resemble Each Other - Appendix B: Answers to Chapter Review Questions.
  • Digital
    Hussein Elkousy, T. Bradley Edwards.
    Contents:
    Shoulder arthroscopy concepts and tools
    Operating room setup
    Diagnostic arthroscopy and normal anatomy
    Glenohumeral instability
    Biceps tendon lesions
    Stiffness
    Arthrosis
    Periarticular cysts and suprascapular nerve compression
    Sepsis or infection
    Impingement syndrome
    Partial-thickness rotator cuff tears
    Full-thickness rotator cuff tears
    Massive rotator cuff tears
    Irreparable rotator cuff tears
    Acromioclavicular joint pathology
    Calcific tendinitis
    Fractures
    Diagnostic ultrasonography
    Rehabilitation.
    Digital Access ClinicalKey 2019
  • Digital
    Saul Goldman, J. Manuel Solano-Altamirano, Kenneth M. Ledez.
    Contents:
    Bubbles in the body
    Driving force of gas-bubble growth and dissolution
    Rates of gas-bubble growth and dissolution in simple liquids
    Estimating the radii and lifetimes of small gas bubbles suspended in simple liquids
    AGEs in scuba diving and in DCS-like problems in breath-hold diving
    Gas bubbles in soft tissue-like solids
    The evils that bubbles do...
    Compartmental decompression models and DCS risk estimation
    Treating the evils that bubbles do
    Gas-bubble dynamics in the treatment of gas-bubble disease.
    Digital Access ScienceDirect 2018
  • Digital
    edited by Yves Huttel.
    Summary: The first overview of this topic begins with some historical aspects and a survey of the principles of the gas aggregation method. The second part covers modifications of this method resulting in different specialized techniques, while the third discusses the post-growth treatment that can be applied to the nanoparticles. The whole is rounded off by a review of future perspectives and the challenges facing the scientific and industrial communities. An excellent resource for anyone working with the synthesis of nanoparticles, both in academia and industry.

    Contents:
    Introduction to Gas Phase Aggregation Sources. History, Some Basics, and an Outlook / Hellmut Haberland
    Principles of Gas Phase Aggregation / Patrice Mélinon
    Types of Cluster Sources / José A De Toro, Peter S Normile, Christopher Binns
    Modifications of Gas Phase Aggregation Sources. The Double-Laser Ablation Source Approach / Piero Ferrari, Jan Vanbuel, Yejun Li, Ting-Wei Liao, Ewald Janssens, Peter Lievens
    In-Plane Multimagnetron Approach / Grant E Johnson, Julia Laskin
    Adjustable Multimagnetron Approach / Lidia Martínez
    Hollow Cylindrical Magnetron / Vitor Toshiyuki Abrao Oiko, Artur Domingues Tavares de Sá, Varlei Rodrigues
    High-Flux DC Magnetron Sputtering / Marco César Maicas Ramos, María del Mar Sanz Lluch
    High-Flux Metal Vapor Cell / Gail N Iles
    Microwave Plasma Synthesis of Nanoparticles / Dieter Vollath
    Enhanced Synthesis of Aggregates by Reduced Temperature, Pulsed Magnetron Sputtering, and Pulsed Buffer Gas Delivery / Vitezslav Stranak, Rainer Hippler
    High-Power Pulsed Plasmas / Iris Pilch
    High-Pressure and Reactive Gas Magnetron Sputtering / Lakshmi Kolipaka, Stefan Vajda
    In-Flight Post-Growth Manipulation of Nanoparticles. Coating / Panagiotis Grammatikopoulos, Mukhles Sowwan
    Nanostructuring, Orientation, and Annealing / Balamurugan Balasubramanian, David J Sellmyer
    Deflection and Mass Filtering / Marcel Di Vece
    In-Flight and Postdeposition Manipulation of Mass-Filtered Nanoparticles under Soft-Landing Conditions / Joachim Bansmann, Armin Kleibert, Hendrik Bettermann, Mathias Getzlaff
    In-Flight Analysis / Sergio D'Addato
    Perspectives. Nano- and Micromanufacturing with Nanoparticles Produced in the Gas Phase: An Emerging Tool for Functional and Length-Scale Integration / Paolo Milani, Luca G Bettini.
    Digital Access Wiley 2017
  • Digital
    Kazunori Kihara, editor.
    Contents:
    Chapter 1. Fundamentals of Gasless Single-Port RoboSurgeon Surgery
    Chapter 2. Gasless Single-Port RoboSurgeon Retroperitoneoscopic Radical Nephrectomy
    Chapter 3. Gasless Single-Port RoboSurgeon Retroperitoneoscopic Partial Nephrectomy
    Chapter 4. Gasless Two-Port Access RoboSurgeon Retroperitoneoscopic Radical Nephroureterectomy
    Chapter 5. Gasless Single-Port RoboSurgeon Retroperitoneoscopic Adrenalectomy
    Chapter 6. Gasless Single-Port RoboSurgeon Retroperitoneoscopic Radical Prostatectomy
    Chapter 7. Gasless Single-Port RoboSurgeon Total Cystectomy with Urinary Diversion
    Chapter 8. Gasless Single-Port RoboSurgeon Partial Cystectomy: A Hybrid Technique Combining an Intravesical and Extravesical approach
    Chapter 9. Gasless Single-Port RoboSurgeon Retroperitoneoscopic Pelvic Lymph Node Dissection and Inguinal Hernia Prevention
    Chapter 10. Application of the RoboSurgeon System in Medical Care.
    Digital Access Springer 2015
  • Digital
    João Ettinger, Euler Ázaro, Rudolf Weiner, Kelvin D. Higa, Manoel Galvão Neto, Andre Fernandes Teixeira, Muhammad Jawad, editors.
    Summary: This book presents and describes the various uses of gastric bypass in bariatric and metabolic surgery and outlines the different techniques currently available. Furthermore, the possible complications with the procedure and ways to avoid them are also discussed. The use of the gastric bypass for the treatment of diabetes is emphasized and the new indications for the operative treatment of diabetes are featured in detail. Endoscopic uses concerning the gastric bypass are also addressed, covering preoperative evaluation, complications treatment, weight regain treatment and endoscopic treatment of obesity. The most advanced techniques and new technologies available for performing gastric bypass surgeries are presented in the most didactic possible way, making use of value-added learning features throughout the text. Gastric Bypass - Bariatric and Metabolic Surgery Perspectives is intended as a practical guide for all those interested and involved with bariatric surgery, including general surgeons, bariatric surgeons, GI surgeons and surgery residents.

    Contents:
    History of the gastric bypass
    Gastric bypass
    Mechanisms of functioning
    Rationale for gastric bypass
    Morbid obesity
    Obesity and related diseases
    Preparing the patient for gastric bypass
    Preoperative weightloss in gastric bypass
    Preoperative testing
    Patient Selection in Metabolic Surgery
    Psychological and psiquiatric issues
    Sleep apnea management
    The superobese patient
    Airway evaluation and management
    Positioning the patient before the procedure
    Developing the laparoscopic Gastric Bypass
    Systemic Inflammation in the Morbidly Obese Patient
    Banded Gastric Bypass by Fobi Ring- Technique and Results
    Psychological and psychiatric issues
    Simplified gastric bypass
    Roux-en-Y gastric bypass in the elderly patient
    Gastric bypass reoperation for weight regain
    Conversion of vertical banded gastroplasty to gastric bypass
    Gastrojejunostomy testing
    Closing the mesenteric defects
    Preventing complications
    ^Laparoscopic gastric bypass
    Tricks and tips
    Psychiatric assistance in bariatric surgery
    Intraoperative complications
    Abdominal Pain after gastric bypass
    Marginal ulceration after (laparoscopic) Roux-en-Y Gastric Bypass: Pathophysiology, Diagnostics, Treatment and Prevention
    Rhabdomyolisis
    Depressive Disorders, Alcohol Use Disorders and Suicidality in Bariatric Surgery
    Nutritional complications
    Eating disorders
    Gallbladder stones and Choledocholitiasis
    Hypoglycemia after Gastric Bypass
    Dumping Syndrome
    Endoscopic treatment of Roux en Y gastric bypass complications
    Endoscopic treatment of weight regain
    Laparoscopic Bariatric Surgery Training and the Credentialing Process
    Training and Credentialing the Robotic Bariatric Surgeon
    Mechanisms of control of diabetes 2 with gastric bypass
    Type 2 diabetes and the gut
    Shifts in The Intestinal Microbiota after Gastric Bypass
    Selecting patients
    ^Gastric bypass in patients with metabolic syndrome^ 35kg/m2
    Gastric bypass for type 2 diabetes BMI <35kg/m2
    Postoperative care
    Mini Gastric Bypass- Why it is better in India than gastric bypass?
    Can Bariatric surgery improve the Microvascular Complications of Type 2 Diabetes?
    Digital Access Springer 2020
  • Digital
    Vivian E. Strong, M.D., F.A.C.S., editor.
    Contents:
    The Historical Perspective of Gastric Cancer
    Epidemiology of Gastric Cancer
    Molecular Mechanisms in Gastric Carcinogenesis
    Pathology of Gastric Cancer
    Role of HER2 in Gastric Cancers
    Pathophysiology of Hereditary Diffuse Gastric Cancer
    Western Perspective and Epidemiology of Gastric Cancer
    Diagnosis, Staging and Workup of Gastric Cancer
    Endoscopy and Endoscopic Ultrasound Examination of the Stomach
    The Role of Staging Laparoscopy and Peritoneal Cytology in Gastric Cancer
    Endoscopic Resection for Gastric Cancer
    Methods of Reconstruction
    BI, BII, Roux-en-Y, Jejunal Interposition, Proximal Gastrectomy and Pouch Reconstruction
    Lymphadenectomy
    D1, D2 and D3
    Open Methods of Resection and Reconstruction for Subtotal and Total Gastrectomy
    Laparoscopic Methods of Resection and Reconstruction for Subtotal and Total Gastrectomy with D2 Lymphadenectomy
    Robotic Methods of Resection and Reconstruction for Subtotal and Total Gastrectomy with D2 Lymphadenectomy
    Managing Early and Late Postoperative Complications Following Gastric Surgery
    Hereditary Diffuse Gastric Cancer
    Surveillance after Gastric Resection
    Surgical Trials for Gastric Cancer
    Neoadjuvant and Adjuvant Treatment
    Strategies and Clinical Trials
    Western Perspective
    Adjuvant and Neoadjuvant Treatment: Standard Treatment and Clinical Trials in the East
    Radiation Treatment for Gastric Cancer
    Targeted Therapy and Novel Agents for the Treatment of Gastric Cancer: A View towards the Future.
    Digital Access Springer 2015
  • Digital
    Giovanni de Manzoni, Franco Roviello, editors.
    Summary: Twenty-five years ago, a monograph on gastric cancer was published by the Italian Society of Surgery: that book is recognized as a milestone in the management of these tumors in Italy. Oncological and surgical knowledge in the field of gastric cancer have changed dramatically over the last 25 years. The aim of this book is to offer an essential update on current diagnostic approaches and optimal treatment strategies. It gives comprehensive information on gastric cancer not neglecting the basic sciences, which can shed light on the carcinogenesis mechanisms involved in this pathology. The principles of tailored and multimodal treatment are examined according to the latest guidelines with the aim of providing a valuable synopsis for clinicians. The book not only reviews what has changed in the field of gastric cancer over the past quarter century but also offers the reader a glimpse of the future by describing the ongoing surgical and oncological trials which focus on new treatment frontiers such as immunotherapy and target therapy. It also seeks to incorporate the latest discoveries based on molecular classifications. Further, the book reflects the findings and experiences of Italian experts belonging to the GIRCG (Italian Research Group for Gastric Cancer) and will offer an excellent guide for oncological surgeons in their daily practice of caring for patients affected by gastric cancer.

    Contents:
    PART I. Epidemiology, Pathology and Diagnosis
    Chapter 1. Epidemiology and risk stratification as a guide for an effective screening strategy in the west
    Chapter 2. Carcinogenesis in the Era of Molecular Classifications
    Chapter 3. Carcinogenesis in the Era of Molecular Classifications
    Chapter 4. The new field of view of endoscopy and histological diagnosis
    Chapter 5. Hereditary gastric cancer
    Part II. Staging
    Chapter 6. EGDS and EUS
    Chapter 7. CT scan and PET/CT scan
    Chapter 8. CT scan and PET/CT scan
    Part III. Treatment
    Chapter 9. Early Gastric Cancer
    Chapter 10. Locally Advanced Gastric Cancer
    Chapter 11. The uncertainty of real life
    Chapter 12. Stage IV
    Chapter 13. Synopsis of Treatment Indications
    Part IV. New frontiers to improve prognosis
    Chapter 14. Tailored Treatment strategies based on new molecular classifications
    Chapter 15. Focus on Poorly Cohesive Gastric Cancer
    Chapter 16. Target Therapy and Immunotherapy
    Part V. Perioperative-management and Follow-up
    Chapter 17. The weight of nutrition in the therapeutic course
    Chapter 18. ERAS protocols
    Chapter 19. Complications after gastrectomy
    Chapter 20. Long-term outcome and follow-up
    Part VI. Technical notes in gastric surgery (Video Content)
    Chapter 21. Laparoscopic D2 dissection
    Chapter 22. D3 open dissection
    Chapter 23. Minimally invasive reconstruction in subtotal gastrectomy
    Chapter 24. Minimally invasive reconstruction total gastrectomy
    Chapter 25. PIPAC
    Chapter 26. Indocyanine green fluorescence
    Chapter 27. ESD.
    Digital Access Springer 2022
  • Digital
    Vincenzo Canzonieri, Antonio Giordano, editors.
    Contents:
    Intro; Preface; Contents; Introduction; References; Contributors; Part I: Gastric Tumorigenesis;
    1: Gastric Tumorigenesis: Role of Inflammation and Helicobacter pylori;
    2: Genetic and Epigenetic Mechanisms in Gastric Cancer; Part II: Clinical and Pathological Characteristics;
    3: Diagnosis and Surveillance: Endoscopic Hallmarks;
    4: Pathological Diagnosis and Classification of Gastric Epithelial Tumours;
    5: Diagnostic, Prognostic, Predictive and Therapeutic Tissue Biomarkers in Gastric Cancer;
    6: Serum Biomarkers in Gastric Cancer; Part III: Gastric Cancer Therapy: Multimodal Treatment Approach
    7: New Agents in the Treatment of Advanced Gastric Cancer: Targeted Therapy and Immunotherap
    y8: Combined Modality Treatment for Locally Advanced Gastric Cancer: Current Evidences and New Perspectives;
    9: Surgical Strategies in Gastric Cancer; Part IV: Evolving Treatment Landscape in Gastric Cancer;
    10: From Molecular Classification to Targeted Therapy for Gastric Cancer in the Precision Medicine Era; Part V: Future Medicine in Gastric Cancer;
    11: Noncoding RNA in Gastric Cancer with Potential Prognostic and Predictive Role;
    12: Immunomodulation and Immunotherapy for Gastric Cancer
    Digital Access Springer 2019
  • Digital
    edited by Qin Huang.
    Summary: This book is designed to present readers with comprehensive, high-quality research results on almost all aspects of this carcinoma in clinical management, from correct determination of the esophagogastric junction, issues on cardiac mucosa, epidemiology, and natural history, to clinical, endoscopic, and histopathologic features and diagnostic pitfalls of this carcinoma at both early and advanced stages. Once diagnosed and correctly staged, clinical management of this carcinoma at the early stage is addressed primarily with endoscopic therapy employing the latest endoscopic technology such as endoscopic submucosal dissection, in which detailed technical topics of the endoscopic therapy are written by experts in the field with sections from pre-resection staging and patient preparation to post-resection complications and management. Subsequently, clinical management of gastric cardiac carcinoma at advanced stages is discussed at length with a personalized, multidiscipline approach with strategies from surgical resections with various methods, to pre-, peri- and post-resection chemoradiation therapies as well as the most advanced immunotherapy. A state-of-art approach with the results of meta-analyses and large-scale randomized double-blinded clinical trials are employed throughout these chapters. For patients at the terminal ill stage, the appropriate palliative care plan is presented by experienced clinicians armed with the latest clinical practice guidelines to better manage and help those patients in the last period of their lives.

    Contents:
    Esophagogastric Junction
    Cardiac Mucosa
    Epidemiology and Risk Factors
    Natural History
    Clinical Molecular Pathology
    Pathology of Early Gastric Cardiac Cancer
    Pathology of Advanced Gastric Cardiac Cancer
    Gastric Lymphoma
    Diagnosis
    Prognosis and Staging
    Endoscopic Resection of Early Gastric Cardiac Carcinoma
    Pathologic Evaluation of Endoscopic Resection Specimens
    Surgical Therapy
    Chemical Therapy
    Radiotherapy and Chemoradiotherapy
    Palliative Care.
    Digital Access Springer 2018
  • Digital
    Gerhard Rogler, Peter Bauerfeind, Michael Fried, Christoph Gubler, Beat Müllhaupt.
    Digital Access Karger 2018
  • Digital
    Jeremy Woodward.
    Summary: In order to understand common conditions such as coeliac disease and Crohn's disease, one must view the gut in its evolutionary context. This is the novel approach to the gut and its diseases that is adopted in this book. The first part tells the story of the evolution of the gut itself - why it came about and how it has influenced the evolution of animals ever since. The second part focuses on the evolution of immunity and how the layers of immune mechanisms are retained in the gut, resembling the strata revealed in an archeological dig. The final part, 'The Gastro-Archeologist', ties the first two together and highlights how understanding the gut and immune system in their evolutionary context can help us understand diseases affecting them. Ambitious in its scope but telling a unique story from a refreshingly novel perspective, the book offers an informative and enjoyable read. As the story of the gut, immunity and disease unfolds, the author aims to endow readers with the same sense of awe and excitement that the subject evokes in him. Difficult concepts are illustrated using simple and colourful analogies, and the main content is supplemented with anecdotes and unusual and amusing facts throughout the book. The book is intended for anyone with an interest in the gut, its immunity and diseases, ranging from school and college biology and biomedical students, to professionals working in the field, and to patients suffering from intestinal diseases who want to understand more about their conditions.

    Contents:
    Selection of the Fattest: The Invention of Eating
    The Gut Revolution
    The Bowels of Existence. The Intestinal Palimpsest: The Rules of Social Engagement
    The Orchestra of Life
    The Layers of Time. The Gastro-Archeologist: 'What is Food to One is Rank Poison to Another': food allergy and Intolerances
    The Evil bread: Coeliac disease and gluten related disorders
    Back to the very Beginning: The Inflammatory Bowel Diseases.
    Digital Access Springer 2021
  • Digital
    [edited by] Josef Neu, Brenda Poindexter ; consulting editor Richard A. Polin.
    Summary: "Dr. Richard Polin's Neonatology Questions and Controversies series highlights the most challenging aspects of neonatal care, offering trustworthy guidance on up-to-date diagnostic and treatment options in the field. In each volume, renowned experts address the clinical problems of greatest concern to today's practitioners, helping you handle difficult practice issues and provide optimal, evidence-based care to every patient"--Publisher's description.

    Contents:
    Maturation of motor function in the preterm infant and gastroesophageal reflux / Anna Maria Hibbs
    Development of gastrointestinal motility reflexes / Sreekanth Viswanathan, Sudarshan R. Jadcherla
    Lipid and fatty acid delivery in the preterm infant : challenges and lessons learned from other critically ill populations / Camilia R. Martin, Steven D. Freedman
    Human milk oligosaccharide / Ardythe L. Morrow, David S. Newburg
    Donor milk trials / Sharon L. Unger, Julia B. Ewaschuk, Deborah L. O'Connor
    Neonatal necrotizing enterocolitis : neonatology questions and controversies / Lauren Astrug, Erika Claud
    Nutrition for the surgical neonate / Holly J. Engelstad, and Brad W. Warner
    Controversies in short bowel syndrome / Jacqueline J. Wessel
    New lipid strategies to prevent/treat neonatal cholestasis / Kathleen M. Gura
    Neonatal gastrointestinal tract as a conduit to systemic inflammation / Mary W. Lenfestey, Josef Neu
    Adult consequences of neonatal and fetal nutrition : mechanisms / Lisa A. Joss-Moore, Cheri Bantilan, Kjersti Aagaard-Tillery, Nicole Mitchell, Clotilde desRoberts, Robert H. Lane
    What are the controversies, and where will the field be moving in the future? / Brenda Poindexter, Josef Neu.
    Digital Access ClinicalKey 2019
  • Digital/Print
    Print Access
    Location
    Version
    Call Number
    Items
    Stored offsite. Please request print.
    43
    Periodicals (Downstairs)
    36
  • Digital
    Matthias W. Wichmann, Timothy K. McCullough, Ian C. Roberts-Thomson, Guy J. Maddern, editors.
    Summary: This book fills a void in the market for specialists who are working in areas without the support of gastroenterologists. Due to a lack of local expertise, treatment decisions in the field of gastroenterology frequently have to be made by non-gastroenterologists. The book addresses this problem by providing clear instructions on the diagnosis, medical management and on-going treatment of the most common disease patterns encountered in gastroenterology. Written by leading experts in their respective fields, it offers up-to-date evidence and insights into these conditions to enable adequate decision-making and safe management of these conditions. -- Provided by publisher.
    Digital Access Springer 2019
  • Digital
    Yvan Vandenplas, editor.
    Summary: This extensively revised second edition of this essential work provides a comprehensive overview of Gastroesophageal Reflux (GER) in children. It contains detailed insight into the epidemiology and pathophysiology of the condition. Relevant diagnostic methods and treatment techniques are also covered. Heavily revised chapters discuss issues associated with GER in special patient populations and current approaches to GER diagnosis and management. New chapters cover relevant aspects of the microbiome, how nutrition can be key to successful treatment and the adverse effects of the latest therapeutic drugs presently available. The first part of the book is dedicated to introducing the condition, discussing epidemiology, symptoms and diagnosis. This is followed by addressing issues of the condition encountered in special patient populations such as in preterm infants, apnea, neulorogic patients and cystic fibrosis, among others. The final part of the book is dedicated to therapeutic approaches from medication to surgery and alternative approaches such as complementary medicine and hypnotherapy. The approaches and challenges in endoscopy are also detailed. Gastroesophageal Reflux in Children, Second Edition is edited by a leading world expert in the topic and written by a global team of authors from a range of associated disciplines, making the work a critical resource for pediatricians, gastroenterologists to pulmonologists, otolaryngologists and neurologists.

    Contents:
    Epidemiology
    Pathophysiology--Gut brain communication
    Pathophysiology--Esophageal clearance
    Symptoms
    Quality of life
    Prognosis of GER
    Diagnosis History
    DiagnosisRadiology
    DiagnosisEndoscopy / histology
    Diagnosis--pH metry impedance
    Diagnosismanometry
    Diagnosis--Ultrasound and other techniques
    GER in cystic fibrosis
    GER in neurologically impaired
    GER after esophageal surgery
    GER in preterm
    GER and allergy
    GER and esonsophilic esophagitis
    GER and dysphagia
    GER and BRUE
    ER and respiratory symptoms
    GER and helicobacter
    GER and duodeno-gastric reflux
    Management of GER in infants
    Management of GER in older children
    Acid secretor blockers and adverse effects
    GER and hypnotherapy
    GER and complementary medicine
    GER and GI microbiome
    GER and surgery
    GER and endoscopic procedures
    Treatment nutrition
    Adverse effects of drugs. .
    Digital Access Springer 2022
  • Digital
    Hiromasa Ohira, Kiyoshi Migita, editors.
    Summary: This book presents research outcomes, providing a big picture of rheumatic diseases as systemic conditions, and exploring the correlation between liver dysfunction and gastrointestinal lesions. Each chapter presents the association between major rheumatic diseases and hepato-gastrointestinal lesions, including liver and gastrointestinal involvement in lupus erythematosus, dermatomyositis, systemic sclerosis, Bechet's disease, and IgG4-related disease. The chapters on PBC-CREST syndrome and immunosuppressive agents broaden readers understanding and enable them to view the diseases from a systematic perspective. Although the disease is rare, it has attracted considerable attention as an intractable disease, and despite the severity of the symptoms, little has been written on the topic. Adopting a multidisciplinary approach, this comprehensive volume thoroughly prepares readers for research in the field of systemic diseases. Gastrointestinal and Hepatic Manifestations of Rheumatic Diseases is a valuable resource not only for hepatologists and rheumatologists, but also clinical residents and medical students.

    Contents:
    1. Liver involvement in rheumatic diseases
    2. Primary biliary cholangitis is associated with CREST syndrome
    3. De novo hepatitis B virus infection
    4. Dermatomyositis and gastrointestinal cancer
    5. Portal hypertension in rheumatic diseases
    6. Gastrointestinal manifestations of systemic lupus erythematosus
    7. Rheumatoid Arthritis and Gastrointestinal Tract Lesions (NSAID ulcers, amyloidosis)
    8. Gastrointestinal involvement of systemic sclerosis
    9. Gastrointestinal involvement of systemic vasculitis
    10. Gastrointestinal involvement of Behçet’s disease
    11. Gastrointestinal involvement in IgG4-related disease
    12. Immunosuppressive agents and intestinal involvement.
    Digital Access Springer 2019
  • Digital
    Poonam Beniwal-Patel, Reza Shaker, editors.
    Summary: This guide provides the answers to patient questions that are frequently posed to practitioners who care for pregnant and non-pregnant women with GI and liver disorders. The first part of the text outlines gender-based differences in GI disorders, including GERD, liver disease, pancreatic disease, IBD, and IBS. The second part of the text reviews common GI and liver diseases that occur during pregnancy, while guiding clinicians through various diagnostic and therapeutic/management approaches. GI and liver diseases that are covered in this section include nausea and vomiting, viral hepatitis, and pregnancy-specific liver disorders such as preeclampsia, HELLP syndrome, and intrahepatic cholestasis. The text concludes with a chapter on the safety of GI procedures for the pregnant patient. Written by experts in the field, Gastrointestinal and Liver Disorders in Women's Health: A Point of Care Clinical Guide is a valuable resource for the busy clinician who needs the best evidence-based answers to patient questions at their fingertips. -- Provided by publisher.

    Contents:
    Part I: Gender-based differences in gastrointestinal disorders: 1. Differential diagnosis between primary eating disorders and disordered eating secondary to a primary gastrointestinal disorder / Jennifer Heinemann and Courtney Barry
    2. Functional swallowing disorders / Livia A. Guadagnoli, John E. Pandolfino, and Rena Yadlapati
    3. Gastroesophageal reflux disease / Rena Yadlapati and Abraham Khan
    4. Cyclic vomiting syndrome : does gender matter? How does it affect the health of women? / Vishnu Charan Suresh Kumar and Thangam Venkatesan
    5. Idiopathic gastroparesis / Dariush Shahsavari and Henry P. Parkman
    6. Autoimmune hepatitis / Margarita N. German and Adnan Said
    7. Diseases of the liver : primary biliary cholangitis / Paulina K. Phillips and Adnan Said
    8. Diseases of the liver : liver masses (hemangioma, focal nodular hyperplasia, hepatic adenoma) / Parul D. Agarwal and Adnan Said
    9. Pancreatic cystic neoplasms in women : mucinous cystic neoplasms, serous cystadenomas, and solid pseudopapillary neoplasms / Harkirat Singh and Asif Khalid
    10. Obesity and bariatric surgery / Semeret Munie and Tammy Kindel
    11. Celiac disease / Marium Khan and Daniel Stein
    12. Inflammatory bowel disease : fertility, menses, and contraception / Reezwana Chowdhury and Sunanda V. Kane
    13. Irritable bowel syndrome in women / Shanti Eswaran and Laura O'Donohue
    14. Chronic constipation / Arnold Wald
    15. Colorectal cancer screening and women / Katherine Hu and Carrie Y. Peterson. Part II: Gastrointestinal/liver diseases during pregnancy: 16. Nausea and vomiting of pregnancy and hyperemesis gravidarum / Sumona Saha
    17. Viral hepatitis : hepatitis B, D, and E viruses / Aiman Ghufran
    18. Pregnancy-specific liver disorders : preeclampsia and HELLP syndrome / Ashina Singh
    19. Pregnancy-specific liver disorders : acute fatty liver / Archita Desai and Deeksha Seth
    20. Intrahepatic cholestasis of pregnancy / Sheila Eswaran, Dharani Guttikonda, and Nancy Reau
    21. Inflammatory bowel disease and pregnancy / Nedhi Patel and Andres Yarur
    22. Gallstone and biliary disease / Gillian L. Fell and David Brooks
    23. Safety of procedures during pregnancy / Bahar Adeli, Erkanda Ikonomi, and Asyia Ahmad.
    Digital Access Springer 2019
  • Digital
    edited by, Amitabh Srivastava, Daniela S. Allende ; series editor, John R. Goldblum.
    Digital Access ClinicalKey 2024
  • Digital
    Pier Alberto Testoni, Haruhiro Inoue, Michael B. Wallace, editors.
    Summary: This unique book is the first to focus on diagnostic and therapeutic endoscopy in gastrointestinal and pancreatico-biliary diseases. It provides an in-depth overview of the state of the art in diagnostic and therapeutic endoscopy of both the digestive tract and the pancreatico-biliary ductal system, and documents the latest innovations in the field. The first part of the book addresses advanced diagnostic and therapeutic endoscopy of the digestive tract, discussing bariatric endoscopic surgery, and the treatment of neoplasia and precancerous lesions of the upper and lower GI tract, motor disorders, GERD, strictures, fistulae and bleeding. The second part of the book is explores ERCP and EUS procedures, covering the diagnosis and therapy of biliary ductal system and pancreatic diseases. Each chapter includes an abundance of color images that document in detail the devices, operative techniques and outcomes. Written by leading internationally renowned experts, the book is a valuable resource for both specialists and residents in gastroenterology and surgery.

    Contents:
    Advanced imaging techniques and in vivo histology: current status and future perspectives (upper G.I.)
    Endoscopic ultrasonography for preoperative staging upper G.I. tract lesions
    Esophageal Neoplasia: Endoscopic Diagnosis and Treatment
    Endoscopic resection of squamous cell carcinoma: techniques and outcomes
    Management of Barretts Esophagus: State of the Art
    Radiofrequency Ablation of Barretts Epithelium
    Cryotherapy and argon ablation of Barretts epithelium
    Resection techniques in Barretts esophagus
    Endoscopic characterization of gastric and duodenal lesions and resection strategy
    Endoscopic submucosal dissection of gastric lesions
    Endoscopic Resection of Submucosal Lesions of the Upper GI Tract: Full-Thickness Resection (EFTR) and Submucosal Tunneling Resection (STER)
    POET and CLEAN-NET for Submucosal Tumor
    Vaters papilla neoplasia: endoscopic ultrasonography for preoperative staging
    Endoscopic Snare Papillectomy
    Endoscopic diagnosis of early duodenal epithelial neoplasias and therapeutic strategy
    Enteroscopy: Techniques and Small Bowel Therapy
    Advanced imaging techniques and in vivo histology: current status and future perspectives (lower G.I.)
    Endoscopic characterization of colorectal lesions and resection strategy
    Endoscopic Mucosal Resection of Colorectal Lesions
    Endoscopic Submucosal Dissection of Colorectal Lesions
    Hybrid technique for difficult colorectal lesions
    Piecemeal EMR Versus ESD for Large Colorectal Lesions: Pros and Cons
    Resection of submucosal lesions of the lower GI tract: full-thickness resection (EFTR), OVESCO
    Endoscopic ultrasonography for preoperative staging of rectal lesions
    Colonoscopy surveillance after adenoma removal: current guidelines
    Management of colonic neoplasia: cost-effectiveness and outcomes of endoscopic therapy
    Advanced techniques in colonoscopy in inherited cancer conditions
    Advanced technique in colonoscopy in inflammatory bowel diseases
    Future technologies for treatment of G.I. tract lesions
    Artificial intelligence for diagnosing G.I. tract lesions
    Endoscopic myotomy and septotomy for Zenkers diverticulum (Z-POEM)
    Peroral endoscopic myotomy (POEM) for achalasia: indications, techniques and outcomes
    Stenting and techniques alternative to POEM for achalasia
    Peroral endoscopic myotomy (POEM) for esophageal motility disorders: indications, techniques and outcomes
    Peroral endoscopic pyloro myotomy (G-POEM)
    Per-rectal endoscopic myotomy
    Transoral fundoplication for treatment of gastro-esophageal reflux disease
    Antireflux mucosectomy (ARMS and ARMA): techniques and outcomes
    Endoscopic radiofrequency (Stretta)
    Endoscopic Treatment for Obesity and Weight Management: State of the Art
    Intragastric occupying space devices
    Endoscopic sleeve gastroplasty
    Aspiration therapy for obesity
    Duodenal resurfacing for treatment of type 2 diabetes
    Endoscopic Management of Complications of Bariatric Therapy
    Endoscopic Management of Weight Regain
    Self expanding stents: present and future
    Endoscopic management of malignant esophageal strictures
    Endoscopic management of strictures of cervical esophagus
    Endoscopic management of benign esophageal strictures
    Biodegradable self-expandable stents for benign strictures: indications and outcomes
    Endoscopic stenting for gastric outlet obstruction
    Endoscopic Ultrasound (EUS)-Guided Gastroenterostomy (EUS-GE)
    Enteroscope-assisted small bowel stenting
    Endoscopic Management of Malignant Colorectal Strictures
    Colorectal Stenting as Bridge to Surgery
    Endoscopic Management of Benign Colorectal Strictures
    Techniques for fistula repair in the G.I. tract
    Stem Cells for Tissue Repair of the GI Tract
    Endoscopic management of acute G.I. non variceal bleeding
    Endoscopic Management of Variceal Bleeding
    Endoscopic management of colonic angiodysplasias
    Full-thickness closure of iatrogenic or post-interventional gastrointestinal defect by the use of flexible endoluminal suturing device
    Difficult biliary cannulation and sphincterotomy: what to do
    Pancreatic Sphincterotomy
    Minor papilla cannulation and sphincterotomy
    Biliary balloon sphincteroplasty
    Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
    ERCP in Surgically Altered Anatomy
    EUS- and enteroscopy-assisted ERCP
    EUS-Guided Pancreatic Duct Cannulation
    Choledochoscopy: techniques and innovation
    Pancreatoscopy: techniques and innovations
    Advanced Intraductal Biliary Imaging
    Treatment of sphincter of Oddi dysfunction
    Treatment of benign biliary strictures
    Treatment of Post-liver Transplant Strictures
    Endoscopic Management of Primary Sclerosing Cholangitis
    Treatment of Malignant Hilar Strictures
    Treatment of malignant distal biliary strictures
    Treatment of Concomitant Malignant Biliary Stricture and Gastric Outlet Obstruction
    Treatment of biliary leaks and fistulae
    Management of Complications of Biliary Stenting
    Intraductal Ablation Therapy in the Biliary Ductal System
    EUS-guided biliary drainage
    EUS-guided bilio-enteric anastomosis
    Advanced intraductal pancreatic imaging
    Treatment of Acute Biliary Pancreatitis
    Treatment of symptomatic pancreas divisum
    Treatment of Pancreatic Leaks and Fistulae
    Trans-papillary drainage of fluid collections
    EUS-Guided Drainage of Fluid Collections
    Treatment of Walled-Off Necrosis
    Treatment of Chronic Obstructive Pancreatitis
    Treatment of Pancreatic Intraductal Stones
    Complications of Pancreatic Stents
    Treatment of pancreatic cancer
    Innovation in Pancreatic Stents
    EUS-guided pancreatico-digestive anastomosis
    Innovation in Lumen Apposing Metal Stents
    Endoscopic Management and Follow-Up of Intraductal Papillary Mucinous Neoplasia (IPMN)
    EUS-Guided Pancreatic Sampling
    EUS Characterization of Focal Pancreatic Masses
    EUS-Guided Thermal Ablation of Pancreatic Neoplasia
    EUS-guided crio-thermal ablation of pancreatic neoplasia
    EUS-guided celiac plexus neurolysis.
    Digital Access Springer 2022
  • Digital
    edited by Pier Alberto Testoni, Haruhiro Inoue, Michael B. Wallace.
    Springer Nature Living Reference.
    Summary: This unique book is the first to focus on diagnostic and therapeutic endoscopy in gastrointestinal and pancreatico-biliary diseases. It provides an in-depth overview of the state of the art in diagnostic and therapeutic endoscopy of both the digestive tract and the pancreatico-biliary ductal system, and documents the latest innovations in the field. The first part of the book addresses advanced diagnostic and therapeutic endoscopy of the digestive tract, discussing bariatric endoscopic surgery, and the treatment of neoplasia and precancerous lesions of the upper and lower GI tract, motor disorders, GERD, strictures, fistulae and bleeding. The second part of the book is explores ERCP and EUS procedures, covering the diagnosis and therapy of biliary ductal system and pancreatic diseases. Each chapter includes an abundance of color images that document in detail the devices, operative techniques and outcomes. Written by leading internationally renowned experts, the book is a valuable resource for both specialists and residents in gastroenterology and surgery.

    Contents:
    PART 1: DISEASES OF GASTROINTESTINAL TRACT: Diagnosis and therapy of upper G.I. neoplasia and pre-cancerous conditions: Advanced imaging techniques and in vivo histology: current status and future perspectives. Endoscopic ultrasonography for preoperative staging upper G.I. tract lesions. Endoscopic characterization of esophageal lesions and resection strategy. Endoscopic management of esophageal squamous cell carcinoma. Endoscopic resection of squamous cell carcinoma: techniques. Management of Barrett's esophagus. Radiofrequency ablation of Barrett's epithelium. Cryotherapy and argon ablation of Barrett's epithelium. Resection techniques in Barrett's esophagus. Endoscopic characterization of gastric and duodenal lesions and resection strategy. Endoscopic mucosal resection of gastric and duodenal lesions. Endoscopic submucosal dissection of gastric lesions. Resection of submucosal lesions of the stomach and duodenum: full-thickness resection (EFTR), submucosal tunneling resection (STER), and Ovesco. Vater's papilla neoplasia: endoscopic ultrasonography for preoperative staging. Papillectomy and ampullectomy
    Diagnosis and therapy of lower G.I. neoplasia and pre-cancerous conditions: Enteroscopy: devices and techniques. Endoscopic therapy of small bowel lesions. Advanced imaging techniques and in vivo histology: current status and future perspectives. Innovations in colonoscopy. Endoscopic characterization of colorectal lesions and resection strategy. Endoscopic mucosal resection of colorectal lesions. Endoscopic submucosal dissection of colorectal lesions. Hybrid technique for difficult colorectal lesions. Endoscopic ultrasonography for preoperative staging of rectal lesions. Endoscopic resection of large rectal lesions: ESD vs TEM. Full-thickness resection of colo-rectal lesions: indications, techniques and outcomes. Piecemeal EMR vs ESD for large colo-rectal lesions; pros and cons. Colonoscopy surveillance after adenoma removal: current guidelines. Management of colonic neoplasia: cost-effectiveness and outcomes of endoscopic therapy. Endoscopic repair after resection and treatment of complications. Future technologies for treatment of G.I. tract lesions
    Therapy of motor disorders of gastrointestinal tract: Endoscopic myotomy and septotomy for Zenker's diverticulum (Z-POEM). Peroral endoscopic myotomy (POEM) for achalasia: indications, techniques and outcomes. Stenting and techniques alternative to POEM for achalasia. Peroral endoscopic myotomy (POEM) for esophageal motility disorders: indications, techniques and outcomes. Endoscopic pyloromiotomy (G-POEM): indications, techniques and outcomes
    Therapy of gastro-esophageal reflux disease: Transoral incisionless fundoplication. Antireflux mucosectomy: techniques and outcomes. Endoscopic augmentation of G-E junction by full-thickness suturing device. Stretta procedure
    Bariatric endotherapy: Endoscopic treatment for obesity and weight management: state of the art. Intragastric ballons. Endoscopic sleeve gastroplasty. Endoscopic gastroplasty techniques. Aspiration therapy. Endoscopic duodenal techniques for treatment of obesity and type 2 diabetes. Endoscopic management of complications of bariatric therapy. Endoscopic management of weight regain. Therapy of gastrointestinal strictures: Self expanding stents: present and future. Endoscopic management of malignant esophageal strictures. Endoscopic management of cervical esophageal strictures. Endoscopic management of benign esophageal strictures. Biodegradable self-expandable stents for benign strictures: indications and outcomes. Endoscopic stenting for gastric outlet obstruction. Endoscopic ultrasound (EUS)-guided gastroenterostomy (EUS-GE). Enteroscope-assisted small bowel stenting. EUS-guided intestinal by-pass procedures. Endoscopic management of malignant colorectal strictures. Colorectal stenting as bridge to surgery. Endoscopic management of benign colorectal strictures
    Therapy of fistulae and bleeding: Techniques for fistula repair in the G.I. tract. Stem cells for tissue repair in the G.I. tract. Techniques for management of acute G.I. non variceal bleeding. Stenting for variceal bleeding
    PART 2: DISEASES OF PANCREAS AND BILIARY DUCTAL SYSTEM: Diagnosis and therapy of biliary ductal system diseases: Difficult biliary cannulation: definition and therapeutic algorithym. Precutting and septotomy techniques. ERCP in surgical altered anatomy. EUS- and enteroscopy-assisted ERCP. ERCP in childhood. Advanced intraductal biliary imaging: OCT, confocal endomicroscopy. Choledochoscopy: imaging, techniques and innovation. Treatment of sphincter of Oddi dysfunction. Treatment of difficult bile duct stones. Treatment of benign biliary strictures. Endoscopic management of primary sclerosing cholangitis. Stenting of malignant biliary strictures. Innovation in biliary stents. Intraductal radiofrequency (RFA) therapy in biliary neoplasia. Intraductal photodynamic therapy in biliary neoplasia. EUS-guided biliary drainage. EUS-guided bilio-enteric anastomosis. Treatment of biliary leaks and fistulae. Diagnosis and therapy of pancreatic diseases: Pancreatic sphincterotomy: technique. Minor papilla cannulation and sphincterotomy: technique. EUS-guided pancreatic duct cannulation. Advanced pancreatic intraductal imaging. Pancreatoscopy: imaging, techniques and innovations. Endoscopic management of acute recurrent pancreatitis. Endoscopic therapy of pancreas divisum. Endoscopic therapy of chronic pancreatitis. Innovation in pancreatic stents. Trans-papillary drainage of pseudocysts. EUS-guided drainage of pseudocysts. Endoscopic management of complications of acute pancreatitis. Endoscopic treatment of pancreatic leaks and fistulae. EUS-guided gastro-pancreatic anastomosis. Endoscopic treatment of "walled off" necrosis. EUS-guided management of pancreatic IPMN. US characterization of pancreatic masses. Endoscopic treatment of pancreatic cancer. EUS-guided termal ablation of pancreatic masses. EUS-guided crio-termal ablation of pancreatic masses.
    Digital Access Springer Live 2020-
    Continuously updated edition
  • Digital
    Aurora D. Pryor, Theodore N. Pappas, M. Stanley Branch, editors.
    Contents:
    Stabilization of Patients Presenting with Upper Gastrointestinal Bleeding
    Urgent Workup for Upper Gastrointestinal Bleeding
    Management of Esophageal Variceal Bleeding
    Management of Dieulafoy?s Lesions
    Management of Bleeding Peptic Ulcer Disease
    Management of Unusual Sources of Upper GI Bleeding
    Mallory?Weiss Syndrome
    Diagnosis and Management of Bleeding Small Bowel Tumors
    Management of Bleeding from the Bile Duct
    Management of Bleeding from the Pancreas
    Urgent Workup of Lower Gastrointestinal Bleeding
    Bleeding Hemorrhoids
    Management of Colonic Diverticular Bleeding and Bleeding Colitis
    Colonic Arteriovenous Malformations
    Bleeding Colorectal Tumors
    Evaluation of the Guaiac Positive Patient
    Endoscopic Techniques for Evaluating Small Bowel Blood Loss: Video Capsule and Device-Assisted Enteroscopy
    Provocative Angiography
    The Unstable Patient with Obscure Gastrointestinal Bleeding: Surgical and Non-surgical Management. .
    Digital Access Springer 2016
  • Digital
    Marko Duvnjak, Lea Smirčić-Duvnjak, editors.
    Summary: This text provides a state-of-the art review of the gastrointestinal complications of diabetes, their pathophysiology, clinical manifestations, diagnostic evaluation and management. Divided into six sections, the volume shows how diabetes affects the entire GI tract, from the oral cavity and esophagus to the large bowel and anorectal region. By offering a detailed diagnostic approach and featuring therapeutic algorithms at the end of each chapter, the text is a useful guideline and reference point for every day practice, specifically in recognizing and diagnosing patients with gastrointestinal complications of diabetes in a timely fashion. Written by experts in the field, Gastrointestinal Complications of Diabetes: A Comprehensive Guide is a valuable resource for physicians dealing with diabetes mellitus or gastrointestinal disorders, and researchers interested in this multidisciplinary problem.

    Contents:
    Diabetes Mellitus
    Chronic Complications of Diabetes
    Summary
    Esophageal and Gastric Function
    Clinical Manifestations
    Diagnostic Approach
    Treatment
    Intestinal Function
    Clinical Manifestations
    Diagnostic Approach
    Treatment
    Anorectal Function
    Clinical Manifestations
    Diagnostic Approach
    Treatment
    Exocrine Pancreatic Function in Diabetes
    Clinical Manifestation
    Diagnostic Approach
    Treatment of Pancreatic Diseases
    Liver Function
    Clinical Manifestations of Liver Disease in Diabetes Mellitus
    Diagnostic Approach
    Nonalchoholic Fatty Liver Disease Treatment.
    Digital Access Springer 2018
  • Digital
    Autumn Graham, David J. Carlberg, editors.
    Summary: This book answers key questions asked by emergency clinicians faced with complex gastrointestinal and abdominal pain presentations. Instead of a traditional format that includes epidemiology, pathophysiology, diagnosis, and treatment options, this book takes an approach that mirrors the way clinicians interact with patients – by asking and answering specific clinical care questions. The book is organized into sections by presentation – gastrointestinal bleeding, for example – each of which contains chapters on specific questions, such as “What is the best clinical risk score for low risk GIB patients?” Each clinical question comes with a detailed, evidence-based response and a summary that gives best practices, recommendations, and references. Additionally, at the end of each section is a chapter titled “Expert Corner,” which asks the same clinical questions to a surgical or gastrointestinal specialist and includes key pearls these experts have for emergency medicine practitioners. Gastrointestinal Emergencies: Evidence-Based Answers to Key Clinical Questions is an essential guide for emergency medicine physicians, residents, and medical students who want to review and improve their care of acute gastrointestinal emergencies.

    Contents:
    General Approach to Management of Acute Abdominal Pain
    Gastrointestinal Bleeding
    Abdominal Pain in the Bariatric Surgery Patient
    Colitis/Diverticulitis
    Appendicitis
    Abdominal Pain in Immunocompromised Patients
    Abdominal Pain in the Pregnant Patient
    Pancreatitis
    IBD
    Vomiting
    Bowl Obstruction
    Gallbladder
    Liver
    Mesenteric Ischemia
    AAA/Dissection.
    Digital Access Springer 2019
  • Digital
    Sreenivasa S. Jonnalagadda, editor.
    Summary: This comprehensive treatise on cutting edge tools and research provides a fascinating insight into the rapidly evolving field of diagnostic and therapeutic endoscopy. Accomplished international researchers and clinicians discuss the latest endoscopic advances in diverse areas including obesity and associated metabolic syndromes, management of peripancreatic fluid collections, endoluminal suturing techniques, fistula closure, management of Barrettℓ́ℓs epithelium, cholangioscopy, chromoendoscopy, high resolution manometry and endoscopic ultrasonography. Gastrointestinal Endoscopy: New Technologies and Changing Paradigms is a valuable resource on the evolving role of endoscopic management of gastrointestinal diseases and is a tremendous resource for gastroenterologists, endoscopists, GI surgeons, and medical residents.

    Contents:
    Barrett?s Esophagus
    Cholangioscopy
    Endoscopic Management of Peripancreatic Fluid Collections and Walled-Off Pancreatic Necrosis
    Bariatric Endoscopy
    Advances in Imaging and Evaluation of the Small Bowel and Colon
    High-Resolution Manometry
    Endoluminal Fistula and Perforation Closure
    Advances in EUS
    Endoscopic Submucosal Dissection
    Colon Widefield EMR.
    Digital Access Springer 2015
  • Print
    editors, Wendy C. Hsu, MD, Co-Director, Diagnostic Radiology Residency, Teaching Coordinator ; Gastrointestinal Imaging, Department of Radiology, Virginia Mason Medical Center, Seattle, Washington, Felicia P. Cummings, MD, Section Chief, General Radiology, Department of Radiology, Virginia Mason Medical Center, Seattle, Washington.
    Contents:
    Pharynx and esophagus
    Stomach
    Small bowel
    Colon and appendix
    Pancreas
    Liver
    Spleen
    Bile ducts and gallbladder
    Peritoneum and retroperitoneum
    Multisystem and miscellaneous.
    Print Access Request
    Location
    Version
    Call Number
    Items
  • Digital
    Mihir S. Wagh, Sachin B. Wani, editors.
    Summary: This volume provides a concise yet comprehensive overview of advanced techniques in interventional endoscopy beyond ERCP and EUS. Comprised of sections on endoscopic resection (including EMR, ESD, STER and EFTR), bariatric endoscopy, endoscopic myotomy (POEM, GPOEM, ZPOEM and PREM), endoscopic anti-reflux therapies, endoscopic tissue apposition, and advances in interventional EUS, the text highlights indications and technical details, assesses safety and efficacy, and provides quality metrics and training pathways for these endoscopic procedures. The book is also accompanied by multiple photos and videos illustrating these endoscopic techniques. Written by world renowned experts in the field, Gastrointestinal Interventional Endoscopy: Advanced Techniques is a valuable resource for gastroenterologists and surgeons interested in the latest advances in interventional endoscopy.

    Contents:
    Part I Endoscopic Resection 1 Endoscopic Lesion Recognition and Advanced Imaging ModalitiesJorge D. Machicado, Jennifer Kolb, Sachin B. Wani 2 Endoscopic Mucosal Resection of the EsophagusSamuel Han, Hazem Hammad 3 Gastric and Duodenal Endoscopic Mucosal ResectionRommel Romano, Pradermchai Kongkam 4 A Pragmatic Approach to Complex Colon PolypsMichael X. Ma, Michael J. Bourke 5 Endoscopic Tools and Accessories for ESD Calvin J. Koh, Dennis Yang, Peter V. Draganov 6 Esophageal ESD Lady Katherine Mejía Pérez, Seiichiro Abe, Raja Siva, John Vargo, Amit Bhatt 7 Gastric ESDTakuji Gotoda 8 Colonic ESDVikneswaran Namasivayam, Yutaka Saito 9 Endoscopic Full Thickness Resection (EFTR) and Submucosal Endoscopic Resection (STER)Mingyan Cai, Marie Ooi, Pinghong Zhou 10 EMR Versus ESD: Pros and ConsVijay Kanakadandi, Mojtaba Olyaee, Amit Rastogi 11 Training and Competency in Endoscopic ResectionDaniel S. Strand, Andrew Y. Wang Part II Bariatric Endoscopy 12 Intra-gastric Balloons and Aspiration TherapyChetan Mittal, Shelby Sullivan 13 Endoscopic Sleeve Gastroplasty (ESG)Gontrand Lopez-Nava, Inmaculada Bautista-Castaño 14 Emerging Endoscopic Therapies for Weight Loss Thomas J. Wang, Marvin Ryou 15 Endoscopic Therapy of Post-Bariatric Surgery Strictures, Leaks and FistulasFilippo Filicori, Lee L. Swanström 16 Endoscopic Management of Weight RegainEric J. Vargas, Andrew C. Storm, Fateh Bazerbachi, Barham K. Abu Dayyeh Part III Endoscopic Myotomy 17 POEM: Pre-procedural work-up and IndicationsJoseph Rayfield Triggs, John E. Pandolfino 18 Peroral Endoscopic Myotomy: Endoscopic TechniquesChetan Mittal, Mihir S. Wagh 19 POEM: Efficacy, Safety, Training and Competency Juergen Hochberger, Volker Meves 20 Endoscopic Myotomy for Zenker's Diverticulum (Z-POEM) Alessandro Fugazza, Roberta Maselli, Alessandro Repici 21 Per-oral Endoscopic Pyloromyotomy (G-POEM) and Per-rectal Endoscopic Myotomy (PREM) Amol Bapaye, Amit Maydeo Part IV Endoscopic Anti-Reflux Therapies 22 History of Endoscopic Anti-reflux Therapies
    Lessons Learned Zaheer Nabi, D. Nageshwar Reddy 23 Transoral Fundoplication for Treatment of Gastroesophageal Reflux DiseasePier Alberto Testoni, Sabrina Gloria Giulia Testoni, Giorgia Mazzoleni, Lorella Fanti 24 Radiofrequency Ablation and Anti-Reflux Mucosectomy for Gastroesophageal Reflux DiseaseBryan Brimhall, Amit Maydeo, Mihir S. Wagh, Hazem Hammad Part V Endoscopic Tissue Apposition 25 Techniques for Endoscopic Suturing Olaya I. Brewer Gutierrez, Stuart K. Amateau 26 Endoscopic Clips and GluesRoupen Djinbachian, Daniel von Renteln Part VI Advances in Interventional EUS 27 Interventional EUS: PancreasVinay Dhir, Ankit Dalal, Carmen Chu 28 Interventional EUS: Bile Duct and GallbladderAnthony Yuen Bun Teoh, Kenjiro Yamamoto, Takao Itoi 29 Interventional Vascular EUSJason B. Samarasena, Kyle J. Fortinsky, Kenneth J. Chang.
    Digital Access Springer 2020
  • Digital/Print
    edited by David Bentrem, Al B. Benson.
    Contents:
    Gastric and small bowel tumors / L. Mark Knab, Anthony Yang
    Pathologic features of esophageal and gastric malignancies / Eduard Matkovic, Michael Schwalbe, Kristina A. Matkowskyj
    Pathologic features of miscellaneous foregut malignancies / Eduard Matkovic, Michael Schwalbe, Kristina A. Matkowskyj
    Management controversies and treatment strategies for borderline resectable pancreatic cancer / Mark S. Talamonti
    Pathologic features of primmary pancreatic malignancies / Ashley M. Cunningham, Patrick S. Rush, Kristina A. Matkowskyj
    Gall bladder cancer / Audrey E. Ertel, David Bentrem, Daniel E. Abbott
    Diagnosis and management of intrahepatic and extrahepatic cholangiocarcinoma / Jason Ho, Steven A. Curley
    Hepatocellular carcinoma: surgical management and evolving therapies / Olga Kantor, Marshall S. Baker
    Clinical features of metastatic hepatic malignancies / Ramiro Fernandez, Sam G. Pappas, David J. Bentrem
    Repeat hepatectomy for colorectal liver metastases / Vikrom Dhar, Ryan M. Thomas, Syed A. Ahmad
    Minimally invasive surgery of the liver / Michael White, Yuman Fong, Laleh Melstrom
    Locoregional therapies for primary and secondary hepatic malignancies / Ahsun Riaz, Robert J. Lewandowski, Riad Salem
    Pathologic features of primary and metastatic hepatic malignancies / Kristina A. Matkowskyj, M. Sambasiva Rao, Guang-Yu Yang
    Robotic rectal cancer surgery / Kurt Melstrom
    Pathologic features of primary colon, rectal, and anal malignancies / Kaitlin E. Sundling, Ranran Zhang, Kristina Matkowskyj
    Importance of adequate lymphadenectomy in gastrointestinal cancer / Andrew Benjami, Ryan P. Merkow
    Circulating tumor cells in gastrointestinal cancer: current practices anbd future directions / Colin M. Court, Jacob S. Ankeny, Shonan Sho, James S. Tomlinson
    Cost-effectiveness analysis in cancer care / Alex Chang, Daniel E. Abbott
    Gastrointestinal malignancy: genetic implications to clinical applications / Nicole E. Lopez, Jen Jen Yeh.
    Digital Access Springer 2016
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RC280.D5 G378 2016
    1
  • Digital
    Michael Korenkov, Christoph-Thomas Germer, Hauke Lang, editors.
    Digital Access Springer 2017
  • Digital
    edited by Gregory Y. Lauwers, Michael B. Wallace ; associate editor, Till Sebastian Clauditz.
    Summary: "This book is intended to help with the microscopic evaluation and the formulation of a differential diagnosis when interpreting gastrointestinal (GI) biopsies (including methods of cytologic acquisition) in the context of the clinical and endoscopic presentation. It is also intended to help gastroenterologists optimize the acquision, and initial handling of biopsy specimens to facilitate an informative diagnosis The goal is to provide a companion to the diagnostic pathologists and to teach pathology residents /fellows, as well as gastroenterologists, the importance of correlating clinical impression, endoscopic findings and microscopic interpretation (with an emphasis on inflammatory and infectious lesions, rather than neoplasms). To assure that the presentation of the material matches "real-life" a standardized format is used for each major entity reported: Clinical presentation, endoscopic appearance and expectations by the gastroenterologist; specific methods, locations, and numbers of biopsy samples needed for specific conditions, and specific handling requirements for specific conditions; the pathologic part of the text will be classic with description of significant architectural changes, but with emphasis on "pathognomonic" characteristics and secondary features; differential diagnosis presented sequentially presented on a) clinical presentation; b) microscopic appearance and c) results of ancillary studies (when performed); suggestions for reporting (i.e., key elements to include in the pathology reports) are offered where appropriate; simple clinical management clues based on the pathologic will conclude each section"-- Provided by publisher.

    Contents:
    PRINCIPAL of BIOSPYDIAGNOSI
    ESOPHAGUS-Inflammatory Conditions
    ESOPHAGUS-Neopastic Conditions
    STOMACH- Inflammatory Conditions
    STOMACH-Polypoid Lesions
    STOMACH- Neoplastic Conditions
    DUODENUM- Inflammatory Conditions
    SMALL INTESTINE-Inflammatory Conditions
    SMALL INTESTINE- Neoplastic Conditions
    COLON Inflammatory Conditions
    COLON-Polypoid Lesions
    COLON-Neoplastic Conditions
    ANUS Inflammatory Conditions
    ANUS- Neoplastic Conditions.
    Digital Access Wiley 2020
  • Print
    Leonard R. Johnson.
    Summary: Gastrointestinal Physiology, a volume in the Mosby Physiology Monograph Series, explains the fundamentals of gastrointestinal physiology in a clear and concise manner. Ideal for your systems-based curriculum, this fully updated medical textbook provides you with a basic understanding of how the GI system functions in both health and disease. New to this edition: Stay abreast of the latest research and findings in physiology with coverage of the physiological significance of gastrointestinal peptides; the regulation of mucosal growth and cancer; details surrounding acid secretion and peptic ulcers; and more. Access new gastrointestinal information on the regulation of pancreatic secretion and gallbladder contraction; the transport processes for the absorption of nutrients; facts about fat absorption; and the regulation of food intake.

    Contents:
    Regulation : peptides of the gastrointestinal tract
    Regulation : nerves and smooth muscle
    Swallowing
    Gastric emptying
    Motility of the small intestine
    Motility of the large intestine
    Salivary secretion
    Gastric secretion
    Pancreatic secretion
    Bile secretion and gallbladder function
    Digestions and absorption
    Fluid and electrolyte absorption
    Regulation of food intake.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    QP145 .G27 2014
    1
  • Digital
    Kim E. Barrett.
    Summary: Gastrointestinal Physiology explains the operation and performance of one of the body's most crucial systems. Using clear, compelling language, the book's presentation makes it easy to absorb the content and integrate it as you learn the physiology of other bodily systems. Written to help you understand essential concepts rather than merely memorize facts, this unique text examines many medically relevant facets of this important body system, including anatomy, pathophysiology, and therapeutics, in concert with physiological information.

    Contents:
    Functional anatomy of the GI tract and organs draining into it
    Neurohumoral regulation of gastrointestinal function
    Gastric secretion
    Pancreatic and salivary secretion
    Water and electrolyte absorption and secretion
    Intestinal mucosal immunology and ecology
    Esophageal motility
    Gastric motility
    Intestinal motility
    Functional anatomy of the liver and biliary system
    Bile formation and secretion
    Gallbladder function
    Bilirubin formation and excretion by the liver
    Ammonia and urea
    Carbohydrate, protein and water soluble vitamin assimilation
    Lipid assimilation.
    Digital Access AccessMedicine 2014
  • Digital
    Leonard R. Johnson.
    Contents:
    Regulation : peptides of the gastrointestinal tract
    Regulation : nerves and smooth muscle
    Swallowing
    Gastric emptying
    Motility of the small intestine
    Motility of the large intestine
    Salivary secretion
    Gastric secretion
    Pancreatic secretion
    Bile secretion and gallbladder function
    Digestion and absorption
    Regulation of food intake.
    Digital Access ClinicalKey 2019
  • Digital
    Eugene Trowers, Marc Tischler.
    Summary: This volume provides a practical hands on guide to gastrointestinal physiology. The book emphasizes an appreciation of basic physiological concepts and their application to novel clinical situations. It exposes the physician-in-training to fundamental principles that are useful in treating patients and lays the groundwork for more advanced study in the future. The authors present relevant cases which incorporate newer adult learning strategies in medical education. These cases provide a forum in which the student can apply acquired knowledge, skills and attitudes. Connections are made to reader's life, whether in the classroom, on the wards or out and about town. Designed for medical students who are studying gastrointestinal physiology for the first time, Gastrointestinal Physiology: A Clinical Approach provides a superb review for upper level medical students and house officers. Nursing and allied health professions students will also find this text to be a useful guide. GI fellows and attending physicians in need of a concise review of fundamental GI physiology principles will also benefit from reading this book.

    Contents:
    Clinical Gastrointestinal Physiology: A Systems Approach
    Form and Function: The Physiological Implications of the Anatomy of the Gastrointestinal System
    Brain-Gut Axis and Regional Gastrointestinal Tract Motility
    Gastrointestinal Secretion: Aids in Digestion and Absorption
    Physiology of the Liver, Gallbladder and Pancreas: "Getting By" with Some Help from Your Friends
    Nutrient Exchange: Matching Digestion and Absorption
    Salt and Water: Intestinal Water and Electrolyte Transport
    Gastrointestinal Manometry: Tales of the Intrepid Transducer.
    Digital Access Springer 2014
  • Digital
    Menizibeya Osain Welcome.
    Summary: This book offers one of the most comprehensive reviews in the field of gastrointestinal (GI) physiology, guiding readers on a journey through the complete digestive tract, while also highlighting related organs and glandular systems. It is not solely limited to organ system physiology, and related disciplines like anatomy and histology, but also examines the molecular and cellular processes that keep the digestive system running. As such, the book provides extensive information on the molecular, cellular, tissue, organ, and system levels of functions in the GI system. Chapters on the roles of the gut as an endocrine, exocrine and neural organ, as well as its microbiome functions, broaden readers' understanding of the multi-organ networks in the human body. To help illustrate the interconnections between the physiological concepts, principles and clinical presentations, it outlines clinical examples such as pathologies that link basic science with clinical practice in special "clinical correlates" sections. Covering both traditional and contemporary topics, it is a valuable resource for biomedical students, as well as healthcare and scientific professionals.

    Contents:
    Intro; Preface; Key Features; Target Groups; Contents; About the Author; 1 History of Development of Gastrointestinal Physiology: From Antiquity to Modern Period and the Birth of Modern Digestive Physiology; Abstract; 1.1 Introduction; 1.2 Organization of the GI System, Periods of Development of Knowledge on the Digestive Physiology; 1.3 Evolutionary Emergence of the Gastrointestinal System; 1.4 Digestive Physiology in Antiquity; 1.5 Digestive Physiology During the Renaissance; 1.6 Digestive Physiology in Modern History; 1.7 The Beginning of Modern Digestive Physiology. 1.8 Current and Emerging Trends in the Study of Physiology1.8.1 The Pendulum of Investigation of Physiological Systems Is Swinging Toward Integrative Approach. The Physiome and Giome Projects; 1.8.2 Bedside-to-Bench or Bench-to-Bedside Physiology-The Cornerstone of Translational Physiology or Medicine; 1.9 Conclusion; Bibliography; 2 Structural and Functional Organization of the Gastrointestinal Tract; Abstract; 2.1 Introduction; 2.2 Structural Architecture of the Gastrointestinal Tract; 2.2.1 Regions of the Gastrointestinal Tract; 2.2.2 Layers of the Gastrointestinal Tract. 2.4.2 Anatomical Architecture of the Lymphatic System2.4.3 Pattern of Lymphatic Drainage of the Gut; Characteristics and Composition of Chyle; Chyle Flow Rate and the Lymphatic Pump; 2.5 Nerve Supply of the Gastrointestinal Tract; 2.6 Functions of the Gastrointestinal Tract; 2.7 Conclusion; Bibliography; 3 Cellular Organization of the Gastrointestinal Tract; Abstract; 3.1 Introduction; 3.2 Brief Historical Background; 3.3 Types of Gastrointestinal Tract Cells; 3.3.1 Muscle Cells of the Gut; 3.3.2 Neurons and Glial Cells of the Gut; 3.3.3 Connective Tissue Cells. 3.3.4 Accessory Cells of the Gastrointestinal Tract3.3.5 Cells of the Accessory Organs of the Digestive System; 3.3.6 Major Types of Gastrointestinal Epithelial Cells; Absorptive Columnar Enterocytes; Mucin-Secreting Cells; Enzyme-Secreting Cells; Acid-Secreting Cells; Neuro-(Entero)endocrine Cells; Gastrointestinal Opioid-Secreting Cells; Gastrointestinal Epithelial Immune Sensor Cell: Paneth Cell; Metaplasia and Dysplasia; 3.4 Structural Composition and Functions of the Cell; 3.4.1 Plasma Membrane; Components of the Plasma Membrane; Lipids; Proteins; Carbohydrates. Tunica Mucosa (Mucous Layer)Tunica Submucosa (Submucous Layer); Tunica Muscularis (Muscle Layer); Tunica Serosa/Adventitia (Serous/Adventitial Layer); 2.2.3 Epithelium of the Gastrointestinal Tract; 2.2.4 Microarchitecture of the Mucosa; 2.2.5 Accessory Organs of Digestion; 2.3 Gastrointestinal Circulation; 2.3.1 Gastrointestinal Venous Circulation; 2.3.2 Gastrointestinal Blood (Arterial) Supply; 2.3.3 Gastrointestinal Perfusion; Regulation of Gastrointestinal Perfusion; Factors Affecting Gastrointestinal Perfusion; 2.4 Gastrointestinal Lymphatic Drainage; 2.4.1 Brief Historical Background.
    Digital Access Springer 2018
  • Digital
    editors: Yukinori Kurokawa and Yoshito Komatsu.
    Summary: This book provides a comprehensive and up-to-date overview of gastrointestinal stromal tumors (GISTs). GISTs represent the most common mesenchymal neoplasms arising within the gastrointestinal tract. The causative gene of this disease was originally discovered in Japan by Prof. Seichi Hirota in 1998, and since then numerous important advances – from basic to clinical aspects – have been reported from Japan. Professionals involved in the management of GISTs inevitably cite significant evidence and the state-of-the-art treatments from the Asian region, where has there is and inherently high prevalence of gastrointestinal cancers. Each expert author elucidates the cutting-edge knowledge on pathophysiology, diagnosis, and treatment of GISTs, especially focusing on the highly valuable data from Japan. This attractive collection benefits not only oncologists but also basic researchers, general physicians and surgeons, as well as paramedical staff and medical students who are dealing with GISTs.
    Digital Access Springer 2019
  • Digital
    Charles R. Scoggins, Chandrajit P. Raut, John T. Mullen, editors.
    Contents:
    Etiology/Epidemiology
    Pathology
    Molecular Genetics of GIST
    Pediatric GIST/Inheritable Disease
    Natural History
    Radiographic Imaging
    Endoscopic Evaluation
    Prognostic Factors for Localized Disease
    Management of Localized GIST: Non-Surgical Approaches-Surveillance and Endoscopic Resection
    Surgery for Localized GIST
    Minimally Invasive Surgery for GIST
    Neoadjuvant Rx and Surgical Consolidation
    Imatinib
    Management of Locally Advanced GIST
    Prognostic Factors for Advanced GIST
    Concepts of Targeted Therapy Management, Dose Escalation, Tailoring Therapy Based on Specific Mutations, Second Line Therapy
    Surgical Debulking of Metastatic GIST
    Liver Resection/Ablation of Metastatic GIST
    Palliative Care.
    Digital Access Springer 2016
  • Digital
    Timothy M. Pawlik, Shishir K. Maithel, Nipun B. Merchant, editors.
    Contents:
    Tracheo-esophageal Fistula
    Esophageal strictures refractory to endoscopic dilatation
    Esophgeal anastomotic leak
    Transhiatal esophagectomy: intraoperative disasters
    Chyle leak after esophageal surgery
    Management of airway, hoarseness and vocal cord dysfunction after esophagectomy
    Severe reflux induced esophagitis
    Introperative solutions for gastric conduit that will not reach
    Injury to the right gastroepiploic artery
    Intraoperative solutions for ischemic gastric conduit
    Jejunal feeding tube complications
    Bile reflux and gastroparesis
    Gastric surgery: dealing with dumping syndrome
    Afferent loop syndrome
    Duodenal stump blowout
    Postoperative complications after surgery for gastric cancer: Anastomotic leakage
    Hepatobiliary and pancreatic surgery: postoperative hepatic insufficiency
    Biliary leaks and thoracobiliary fistula
    Contralateral bile duct injury during hepatic resection
    Massive Intra-operative Hemorrhage During Hepato-Biliary and Pancreatic Surgery
    Hepatobiliary and Pancreatic Surgery: Intraoperative injury to Hepatic Arterial Structures
    Hepatobiliary and pancreatic surgery: hepatic abscess
    Hepaticojejunostomy anastomotic strictures
    Stricture at Pancreatico-Jejunostomy or Pancreatico-Gastrostomy
    Postoperative Portal, Mesenteric and Splenic Vein Thrombosis
    Post-pancreatectomy Hemorrhage: Early and Late
    Major Disruptions of Pancreaticojejunostomy
    Persistent Pancreatic Fistula
    Management of Chyle Leaks Following Pancreatic Resection
    Hepatobiliary and Pancreatic Surgery: Preventing Pancreatic Fistula following Distal Pancreatectomy
    Pearls for the Small Bowel and Colon That Will Not Reach
    Anastomotic Leak / Pelvic Abscess
    Management of Anastomotic Stricture
    Colorectal Surgery: Intraoperative Ureteral Injury
    Colorectal surgery: Prostatic Urethral Injury
    Vaginal Injury During Stapled
    Anastomosis
    Management of rectovaginal fistula
    Management of Presacral / Pelvic Bleeding
    Breakdown / Nonhealing of Perineal Wound
    Complications after TEM (Transanal Endoscopic Microsurgery) and TAMIS Maria
    Parastomal hernia
    Stoma Retraction/Ischemia/Stenosis
    Incontinence after Lateral Internal Sphincterotomy/ Fistulotomy
    Anal Stenosis after Hemorrhoidectomy: Avoidance and Management
    Delivering Bad News: Conversations with My Surgeon.
    Digital Access Springer 2015
  • Digital
    Anna Ibele, Jon Gould, editors.
    Summary: This book presents a comprehensive approach to the diagnostic evaluation of gastroparesis and the medical and surgical treatment options available for this disorder. The initial chapters address the different etiologies, pathophysiology and diagnostic evaluation of this disease. Medical management, nutritional support and co-morbid conditions are also discussed. Subsequent chapters focus on endoscopic and surgical options for management and the current outcomes data for these procedures. A brief review of the existing literature addressing the particular topic is included in each section. Written by experts in the field, Gastroparesis covers each of these treatment sections that address patient selection, technical conduct and complications of the most common endoscopic procedures and operations, and anticipated outcomes of therapy. .

    Contents:
    Normal Gastric Motility
    Etiology and Clinical Presentation of Gastroparesis
    Diagnostic Evaluation of Gastroparesis
    Medical Management of Gastroparesis
    Endoluminal Management of Gastroparesis
    Gastric Electrical Stimulation
    Laparoscopic Pyloroplasty
    Post-Surgical Gastroparesis
    Management of Gastroparesis in the setting of Gastroesophageal Reflux Disease
    Managing Gastroparesis in the Setting of Obesity.
    Digital Access Springer 2020
  • Digital
    edited by Richard McCallum, Henry Parkman, John Clarke, Braden Kuo.
    Contents:
    Historical perspectives on gastric motility and gastroparesis
    Epidemiology of gastroparesis
    Clinical presentations of gastroparesis
    Natural history of patients with gastroparesis
    Gastric dysmotility at the organ level in gastroparesis
    Cellular pathogenesis of gastroparesis
    Sensory dysfunction in gastroparesis
    Pathology of gastroparesis: ICC, enteric neurons and fibrosis
    Gastroparesis and the brain-gut axis
    Autonomic neuropathies and gastroparesis
    Gastric emptying scintigraphy
    The use of wireless motility capsule in the diagnosis and monitoring of gastroparesis
    Breath tests for the assessment of gastroparesis
    Magnetic resonance imaging for gastric motility and function
    Electrogastrography for suspected gastroparesis
    Antroduodenal manometry for the evaluation of patients with suspected gastroparesis
    Ancillary testing including barostat, SPECT, and satiety testing
    Diabetic gastroparesis
    Postsurgical gastroparesis
    Idiopathic gastroparesis
    Gastroparesis from other causes
    Pediatric gastroparesis
    Dietary therapy for gastroparesis
    Prokinetic agents for gastroparesis
    Antiemetic therapy for gastroparesis
    Abdominal pain in gastroparesis: Prevalence, potential causes and management
    Psychiatric aspects of gastroparesis
    Alternative, complementary medicine and cannabinoids for gastroparesis
    Enteric tube placement for gastroparesis: Gastrostomy, gastrojejunostomy and jejunostomy
    Gastric electrical stimulation for gastroparesis
    Surgical management of gastroparesis
    Studies from the NIH Gastroparesis Clinical Research Consortium: Towards improving our understanding and treatment of gastroparesis
    Evaluating response in gastroparesis: Patient reported outcome measures and survey instruments
    The pyloric revolution: Patient selection
    Endoscopic full-thickness gastric biopsy: Ready for prime time?
    Distinguishing between functional dyspepsia and gastroparesis: Does it matter?
    Female predominance in gastroparesis
    A brief history and future directions of permanent, temporary, and endoscopic GES
    Cell transplantation for gastroparesis
    A vision of the future for gastroparesis
    Resources for the gastroparesis patient.
    Digital Access ClinicalKey 2020
  • Digital
    edited by W. Curt LaFrance Jr., Steven C. Schachter.
    Summary: "The first edition of Non-Epileptic Seizures was published in 1993 and edited by Drs. A. James Rowan and John R. Gates. Based on a 1990 symposium called "The Dilemma of Non-Epileptic (Pseudoepileptic) Seizures," this instant classic synthesized the available knowledge and hypotheses regarding all facets of nonepileptic seizures into four sections: neurological, psychiatric and neuropsychological aspects, and fundamentals of treatment. The second edition was published in 2000 and reflected the continued outgrowth of the 1993 symposium as well as a second conference - "Non-Epileptic Seizures: A Consensus Conference on Diagnosis and Treatment - held in Bethesda in 1996. A third conference, "The 2005 Psychogenic Nonepileptic Seizures (PNES) Treatment Workshop, sponsored by the NINDS, the NIMH, and the American Epilepsy Society and organized by W. Curt LaFrance, Jr., brought together experts from around the world, representing many disciplines. The enthusiasm emanating from that landmark meeting reverberated widely amongst professionals interested in the evaluation and treatment of persons with PNES. Sadly, the field soon afterwards lost its pioneers: John Gates on September 28, 2005 and Jim Rowan on August 27, 2006"--Provided by publisher.
    Digital Access Cambridge 2018
  • Digital
    [edited by] Vijaya B. Reddy, Odile David, Daniel J. Spitz, Meryl H. Haber.
    Digital Access
    Provider
    Version
    ScienceDirect
    ClinicalKey
  • Digital
    R. Vinoth Kumar, editor.
    Summary: This book provides in-depth information on all key aspects of geminivirus biology, e.g. the genetics and evolution, global diversity and spread of these plant pathogens, as well as the molecular mechanisms underlying their virulence. Geminiviridae is one of the largest viral families, comprising numerous plant-infecting viruses that cause diseases in crops and weeds. These diseases have been reported from nearly all continents, in particular Asia, Europe, Africa and America. The book summarizes the current state of knowledge on the interactions between plant host and virus. In addition, it discusses advances regarding the trans-replication of satellite molecules and its effect on geminiviral pathogenesis, as well as pest management strategies to combat these diseases in the field. Given its scope, the book is a must-read reference guide for all researchers and advanced students working in virology, agriculture and plant biotechnology.

    Contents:
    Intro; Preface; Contents; List of Contributors; Classification, Taxonomy and Gene Function of Geminiviruses and Their Satellites; 1 Family: Geminiviridae; 1.1 Geminivirus Taxonomy; 1.1.1 Genus: Becurtovirus; 1.1.2 Genus: Begomovirus; 1.1.3 Genus: Capulavirus; 1.1.4 Genus: Curtovirus; 1.1.5 Genus: Eragrovirus; 1.1.6 Genus: Grablovirus; 1.1.7 Genus: Mastrevirus; 1.1.8 Genus: Topocuvirus; 1.1.9 Genus: Turncurtovirus; 1.2 Biological Functions of Geminivirus Components; 1.2.1 DNA-A Component; 1.2.2 DNA-B Component; 1.2.3 Betasatellites; 1.2.4 Alphasatellites; 1.2.5 Deltasatellites; References 1.1 Geminiviruses1.2 Geminivirus Evolution; 1.3 Disease Symptoms; 2 Geminiviruses Occurrence in Australia, China, Europe, and the Middle East Countries; 2.1 Geminiviruses in Australia; 2.2 Geminiviruses in China; 2.3 Geminiviruses in Europe; 2.4 Geminiviruses in the Middle East Countries; 3 Future Aspects; References; Mastreviruses in the African World: Harbouring Both Monocot and Dicot Species; 1 Introduction; 2 Mastreviruses: Distribution and Diversity; 2.1 Maize Streak Virus; 2.2 Panicum Streak Virus; 2.3 Chickpea Chlorotic Dwarf Virus; 2.4 Urochloa Streak Virus; 2.5 Sugarcane Streak Virus 3 Geminivirus Transcription4 Transcript Mapping in Geminiviruses; 5 Geminiviruses Promoter; 5.1 Early Promoter; 5.2 Late Promoters; 6 Transactivator C2/AC2 Regulation; 7 Concluding Remarks; References; Distribution of Geminivirus in the Indian Subcontinent; 1 Introduction; 2 Family Geminiviridae; 3 Geminiviruses in Indian Subcontinent; 4 Genus Capulavirus (Type Species: Caput-Medusae Latent Virus, CMLV); 4.1 Introduction; 4.2 Important Capulavirus in Indian Subcontinent; 4.2.1 French Bean Severe Leaf Curl Virus; 5 Genus Mastrevirus (Type Species: Maize Streak Virus, MSV); 5.1 Introduction 5.2 Important Mastreviruses of the Indian Subcontinent5.2.1 Wheat Dwarf India Virus; 5.2.2 Chickpea Chlorotic Dwarf Virus; 5.2.3 Sugarcane Streak Virus; 6 Genus Begomovirus (Type Species: Bean Golden Mosaic Virus, BGMV); 6.1 Introduction; 6.2 Important Crops Affected by Begomovirus in the Indian Subcontinent; 6.2.1 Tomato; 6.2.2 Okra; 6.2.3 Legumes; 6.2.4 Chilli; 6.2.5 Cassava; 6.2.6 Cucurbits; 6.2.7 Cotton; 6.2.8 Papaya; 6.2.9 Mesta; 6.2.10 Radish; 6.2.11 Jatropha; 7 Conclusion; References; Geminivirus Occurrence in Australia, China, Europe, and the Middle Eastern Countries; 1 Introduction Rolling Circle Replication and Transcription Processes in Geminiviruses1 Geminivirus Replication; 1.1 Rolling Circle Replication; 1.1.1 Viral Proteins Involved in Replication Process; 1.2 Recombination-Dependent Replication; 2 Interactions with Rep Protein and Its Implication on Viral DNA Accumulation; 2.1 Plant Retinoblastoma-Related Proteins (RBR); 2.2 Proliferating Cell Nuclear Antigen (PCNA); 2.3 Replication Factor C (RFC); 2.4 Replication Protein A-32 (RPA-32); 2.5 Recombination Enzymes; 2.6 Sumoylation-Conjugating Enzyme-1; 2.7 Histones; 2.8 NAC Domain-Containing Proteins
    Digital Access Springer 2019
  • Digital/Print
    Roberta Katz, Sarah Ogilvie, Jane Shaw & Linda Woodhead.
    Summary: "Our newest generation, Generation Z, or Zoomers, are coming of age in a world rife with amazing new opportunities and unprecedented challenges. Born around the time the World Wide Web made its public debut in 1995, they are "digital natives," the first generation never to know the world without the Internet. They have grown up alongside powerful global networks that offer endless information and connectivity. They have also had the clear realization that their elders know no better than they do how to navigate ongoing crises; that they and their planet have been badly betrayed by decisions which preceded them. In Gen Z, Explained, a team of social scientists set out to take a comprehensive look at this generation, drawing on wide and lively interviews, surveys, and comprehensive linguistic analysis (deploying the authors' proprietary iGen Corpus, a 70-million word collection of Gen-Z-specific English language scraped from social media, time-aligned video transcriptions, and memes). It paints a portrait of an extraordinarily challenged, thoughtful, and promising generation--while sounding a warning to their elders. The authors show that despite all the seemingly insurmountable difficulties they face, this generation continues to be idealistic about the future and highly motivated to make change"-- Provided by publisher.

    Contents:
    Introduction
    Technology shapes postmillenial life
    Fine-grained identity
    Being authentic
    Finding my fam
    OK Boomer
    The difficulty of being a Gen Zer
    Conclusion : the art of living in a digital age.
    Print Access
    Location
    Version
    Call Number
    Items
    Digital: Document
    Books: General Collection (Downstairs)
    HQ799.5 .K37 2021
    1
  • Digital
    Anna R. Hemnes, editor.
    Contents:
    Introduction
    1.Sex Differences in Normal Pulmonary Structure and Function at Rest and during Exercise
    2.Sex Hormone Signaling In The Lung In Health And Disease: Airways, Parenchyma And Pulmonary Vasculature
    3.Women and COPD
    4.Sex, gender, and asthma
    5.Sex hormones, sex, gender and pulmonary hypertension
    6.Pulmonary Fibrosis
    7.Sex-Specific Differences in Lung Cancer
    8.Lymphangioleiomyomatosis
    9.Developmental Lung Disease. .
    Digital Access Springer 2016
  • Digital
    edited by Christopher J. Salgado, Stan J. Monstrey, Miroslav L. Djordjevic ; assistant editor Harvey W. Chim.
    Contents:
    Facial feminization surgery : a global approach / Luis Capitan, Daniel Simon
    Speech modification / James P. Thomas
    Top surgery / Britt Colebunders, Salvatore D'Arpa, Stan J. Monstrey
    Combined hysterectomy, oophorectomy, and chest reconstruction in the female-to male transgender patient / Christopher J. Salgado, Renee Gasgarth, Lydia A. Fein, Christopher Estes
    Male-to-female gender affirmation skin-flap vaginoplasty / Miroslav L. Djordjevic, Dusan Stanojevic, Marta Bizic
    Male-to-female gender affirmation colon vaginoplasty : total laparoscopic
    Sigmoid vaginoplasty / Mark-Bram Bouman, Wouter B. van der Sluis, Marlon E. Buncamper, Wilhelmus J.H.J. Meijerink
    Female-to-male gender affirmation metoidioplasty / Marci L. Bowers, Borko Stojanovic, Marta Bizic
    Female-to-male gender affirmation phalloplasty : radial forearm flap / Christopher J. Salgado, Harvey Chim, Varsha R. Sinha, Piet Hoebeke, Stan J. Monstrey
    Anterolateral thigh flap phalloplasty / Stan J. Monstrey, Salvatore D'Arpa, Britt Colebunders, Nicolaas Lumen, Piet Hoebeke
    Expert commentary / Curtis Crane, Klara Sputova
    Female-to-male gender affirmation phalloplasty : latissimus dorsi flap / Miroslav L. Djordjevic, Sinisa Kojic, Borko Stojanovic
    Testicular and erectile implants in transmen after phalloplasty / Piet Hoebeke, Nicolaas Lumen
    Management of unfavorable urologic sequelae following phalloplasty in
    Transgender patients / Yuka Yamaguchi, Jamie P. Levine, Lee C. Zhao
    Unfavorable results in phalloplasty surgery / Salvatore D'Arpa, Nicolaas Lumen, Piet Hoebeke, Christopher J. Salgado, Vishal K. Sinha, Natalie Joumblat, Stan J. Monstrey
    Medical treatment of the adolescent transgender patient / Daniel E. Shumer, Norman P. Spack
    Adult hormonal therapy in the transsexual patient / Melany Castillo, Roy E. Weiss
    Mental health care for transgender and gender-nonconforming children, adolescents, and adults / Walter O. Bockting, Amir Adam Tarsha, Yasmina Zoghbi, Clara Alvarez-Villalba
    Sexual health issues following surgery for transgender individuals / Marilyn K. Volker, Lydia A. Fein
    Gender expression and image / Michelle Horne, Lydia A. Fein.
  • Digital
    Ethel Tur, Howard I. Maibach, editors.
    Summary: This book comprehensively reviews the characteristics of the body reflected in the skin due to differences in gender. It investigates the genetic and hormonal differences that can affect skin structure and function, and resulting in variations between women and men. The aging process and exogenous factors that differ according to differences in lifestyle between the sexes are also covered. Gender and Dermatology comprehensively outlines the various aspects of physiological differences between the skin of women and men using practical examples and review of the basic science. It is therefore an important clinically-relevant review for both the trainee and experienced practitioner in dermatology, primary care, geriatrics and immunology, while also being of interest to researchers in genetics and metabolic medicine. .
    Digital Access Springer 2018
  • Digital
    Antoinette Maassen van den Brink, E. Anne MacGregor, editors.
    Summary: This book focuses on the influence of sex and gender in migraine, presenting new insights in basic science as well as their clinical relevance. As migraine is roughly three times more common in women than in men, and also highly depends on hormonal milestones – such as menarche, menstruation, pregnancy and menopause – particular attention is devoted to the role of female sex hormones in this disease. The first chapters present general data on gender-related differences in migraine such as epidemiology, comorbidities and related risks. Furthermore, while several chapters focus on the role of female sex hormones in migraine-triggering mechanisms at a basic scientific level (e.g. cranial circulation), ample attention is also paid to the clinical relevance of such mechanisms and to the best clinical treatment for migraine patients. As the first book entirely devoted to this topic, it will be of interest to researchers and practitioners in the fields of neurology, internal medicine, endocrinology, physiology and pharmacology.

    Contents:
    Intro; Foreword; Preface; Contents;
    Chapter 1: Epidemiology of Migraine in Men and Women; 1.1 Introduction; 1.2 Prevalence of Migraine; 1.2.1 Subtypes of Migraine; 1.2.2 Incidence and Age at Onset; 1.3 Natural History/Prognosis; 1.4 Phenotype; 1.5 The Impact of Migraine; 1.5.1 Individual Burden; 1.5.2 Societal Burden; References;
    Chapter 2: Cardiovascular Risk of Migraine in Men and Women; 2.1 Introduction; 2.2 Epidemiological Outcomes of Cardiovascular Risks in Migraineurs; 2.3 Pathophysiological Mechanisms of Migraine and Cardiovascular Disease; 2.3.1 Endothelial Dysfunction 2.3.2 Platelet Abnormalities2.3.3 Microemboli; 2.3.4 Shared Genetic Markers; 2.4 Gender Differences in Migraine and Cardiovascular Risk; 2.4.1 The Role of Hormones; 2.5 Biomarkers and Markers of Subclinical Vascular Disease; 2.6 Consequences for the Clinical Practice and for Healthcare Professionals; 2.7 Gaps and Future Research; 2.8 Conclusions; References;
    Chapter 3: Sex- and Gender-Specific Aspects of Migraine Treatment; 3.1 Gender Differences in Migraine Prevalence; 3.2 Female-Specific Migraine Subtypes; 3.2.1 Migraine During Perimenopause and Postmenopause 3.3 Hormonal Fluctuations Throughout the Menstrual Cycle3.3.1 Role for Hormonal Fluctuations in Migraine; 3.3.2 Current Knowledge on Sex Hormone Levels in Women with Migraine; 3.4 Female-Specific Migraine Treatments; 3.4.1 Acute Migraine Treatment Options in PMM and MRM; 3.4.1.1 Acute Non-migraine-Specific Treatments; 3.4.1.2 Acute Migraine-Specific Treatments; 3.4.2 Short-Term Prophylactic Treatment Options in PMM and MRM; 3.4.2.1 Short-Term Non-migraine-Specific Treatments; 3.4.2.2 Short-Term Migraine-Specific Treatments; 3.4.3 Female-Specific Prophylactic Treatment Options 3.4.3.1 Oral Contraceptives3.4.3.2 Other Female-Specific Prophylactic Migraine Treatments; 3.4.4 Migraine Treatment in Perimenopausal and Postmenopausal Women; 3.5 Summary and Conclusion; References;
    Chapter 4: Headache and Pregnancy; 4.1 Introduction; 4.2 Clinical Headache Phenotypes and Observational Studies in Pregnancy; 4.2.1 Primary Headaches; 4.2.1.1 Migraine; 4.2.1.2 Tension-Type Headache; 4.2.1.3 Cluster Headache; 4.2.2 Secondary Headaches; 4.2.2.1 Preeclampsia and Eclampsia; 4.2.2.2 Cerebral Venous Thrombosis; 4.2.2.3 Ischemic Stroke; 4.2.2.4 Subarachnoid Hemorrhage 4.2.2.5 Arterial Dissection4.2.2.6 Reversible Cerebral Vasoconstriction Syndrome; 4.2.2.7 Posterior Reversible Encephalopathy Syndrome; 4.2.2.8 Idiopathic Intracranial Hypertension; 4.2.2.9 Pituitary Apoplexy; 4.3 Treatment of Headaches in Pregnancy and Breastfeeding Women; 4.3.1 Non-pharmacological Treatment; 4.3.2 Symptomatic Treatment; 4.3.2.1 Paracetamol/Acetaminophen; 4.3.2.2 Aspirin; 4.3.2.3 Caffeine; 4.3.2.4 Nonsteroidal Anti-inflammatory Drugs; 4.3.2.5 Triptans; 4.3.2.6 Oxygen; 4.3.2.7 Lidocaine; 4.3.2.8 Corticosteroids; 4.3.2.9 Opioids; 4.3.2.10 Ergots and Ergots Alkaloids
    Digital Access Springer 2019
  • Digital
    Loren S. Schechter, editor.
    Summary: Gender confirming surgery represents one of many therapies for individuals with gender dysphoria and can be pivotal in allowing individuals to become their true selves. An emerging field, this text represents a continuing evolution of surgical techniques, as well as a framework around which surgical therapies are based. Providing a fundamental understanding of the surgical principles while also recognizing the fast-paced nature of the advances in technique, Gender Confirmation Surgery touches upon the challenges and complexities in the surgical care of transgender individuals, featuring detailed sections for transwomen and transmen surgeries, non-surgical options, and establishing educational programs. Written as a guide primarily for surgeons in plastics, urology, and gynecology, this book can also appeal to primary care practitioners, mental health professionals, and endocrinologists. By representing an evolution of technique and advances in the field, Gender Confirmation Surgery offers a framework around which practitioners can familiarize themselves with gender surgery.

    Contents:
    CH 1 History, Societal Attitudes, Contexts
    CH 2 Etiology of Gender Dysphoria
    CH 3 The Mental Health Assessment for Surgery
    CH 4 Primary Care for the Transgender and Gender Nonconforming Patient
    CH 5 Hormone Therapy for Transgender Women
    CH 6 Hormone Therapy for Transgender Men
    CH 7 Medical Management of the Adolescent Individual with Gender Dysphoria
    Ch 8 Establishment of a Gender Confirmation Program
    CH 9 Male-to-Female Breast Augmentation and Body Contouring
    CH 10 The Importance of Facial Gender Confirmation Surgery
    CH 11 Facial Gender Confirmation Surgery: Facial Feminization Surgery and Facial Masculinization Surgery
    CH 12 Fertility Preservation Options for Transgender Men Planning Hysterectomy
    CH 13 Penile Inversion Vaginoplasty
    CH 14 Intestinal Vaginoplasty
    CH 15 Female-to-Male Chest Reconstruction
    CH 16 Urethral Anatomy, Urethral Construction in Phalloplasty and Metoidioplasty
    CH 17 MLD Musculo-Cutaneous Latissimus Dorsi) Phalloplasty
    CH 18 Radial Forearm (RF) and Anterolateral Thigh (ALT) Phalloplasty Reconstruction
    CH 19 Management of Urethral Complications Following Metoidioplasty and Phalloplasty
    CH 20 Strategies to Optomize Sexual Function After Genital Gender Affirming Surgery
    CH 21 Post Operative Care from the Primary Care Perspective
    CH 22 Religious Attitudes Toward Gender Confirmation Surgery
    CH 23 History of Gender Identity and Surgical Alteration of the Genitalia
    CH 24 Terminology, Spectrum of Gender Identity and Expression.
    Digital Access Springer 2020
  • Digital
    Jawahar L. Mehta, Jean McSweeney, editors.
    Summary: This book reviews all aspects of the diagnosis and management of heart disease in women, covering areas such as gender differences in metabolic syndrome, hypertension and atherogenesis. Gender differences in cardiovascular diseases are widespread, but while gender medicine takes into account the effects of sex and gender on the health of women and men, traditionally, women have been underrepresented in cardiovascular clinical trials, in management of different cardiac diseases and drug use. Gender Differences in the Pathogenesis and Management of Heart Disease deals with the gender-specific differences in cardiac physiology and diseases and brings into perspective the critical significance of gender in management of cardiovascular disease presentations and management. As such it is of enormous use to all clinical staff who manage women with cardiovascular disease.
    Digital Access Springer 2018
  • Print
    by Maia Kobabe ; colors by Phoebe Kobabe.
    Summary: "In 2014, Maia Kobabe, who uses e/em/eir pronouns, thought that a comic of reading statistics would be the last autobiographical comic e would ever write. At the time, it was the only thing e felt comfortable with strangers knowing about em. Now, Gender Queer is here. Maia's intensely cathartic autobiography charts eir journey of self-identity, which includes the mortification and confusion of adolescent crushes, grappling with how to come out to family and society, bonding with friends over erotic gay fanfiction, and facing the trauma and fundamental violation of pap smears. Started as a way to explain to eir family what it means to be nonbinary and asexual, Gender Queer is more than a personal story: it is a useful and touching guide on gender identity--what it means and how to think about it--for advocates, friends, and humans everywhere."--Amazon.
    Print Access Request
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    HQ77.8.K628 A3 2020
    1
  • Digital
    Rylan Jay Testa, PhD, Deborah Coolhart, PhD, Jayme Peta, MA.
    Summary: "This one-of-a-kind, comprehensive workbook will help you navigate your gender identity and expression at home, in school, and with peers, "--Amazon.com.

    Contents:
    Gender identity
    Gender expression
    Family
    School and work
    Friends and other peers
    Dating and sex
    Balancing multiple identities
    Dealing with the hard stuff.
  • Digital
    Siddhartha Mukherjee.
    Summary: The Pulitzer Prize-winning author draws on his scientific knowledge and research to describe the magisterial history of a scientific idea, the quest to decipher the master-code of instructions that makes and defines humans; that governs our form, function, and fate; and that determines the future of our children. The story of the gene begins in earnest in an obscure Augustinian abbey in Moravia in 1856 where Gregor Mendel, a monk working with pea plants, stumbles on the idea of a "unit of heredity." It intersects with Darwin's theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms postwar biology. It invades discourses concerning race and identity and provides startling answers to some of the most potent questions coursing through our political and cultural realms. It reorganizes our understanding of sexuality, gender identity, sexual orientation, temperament, choice, and free will, thus raising the most urgent questions affecting our personal realms. Above all, the story of the gene is driven by human ingenuity and obsessive minds--from Mendel and Darwin to Francis Crick, James Watson, and Rosalind Franklin to the thousands of scientists working today to understand the code of codes. Woven through the book is the story of Mukherjee's own family and its recurring pattern of schizophrenia, a haunting reminder that the science of genetics is not confined to the laboratory but is vitally relevant to everyday lives. The moral complexity of genetics reverberates even more urgently today as we learn to "read" and "write" the human genome--unleashing the potential to change the fates and identities of our children and our children's children.--Adapted from dust jacket.

    Contents:
    Prologue: Families
    "The missing science of heredity" 1865-1935
    "In the sum of the parts, there are only the parts" 1930-1970
    "The dreams of geneticists" 1970-2001
    "The proper study of mankind is man" 1970-2005
    Through the looking glass 2001-2015
    Post-genome 2015-...
    Epilogue: Bheda, Abheda.
    Limited to 3 simultaneous users
  • Digital
    Elizabeth P. Rakoczy, editor.
    Summary: In this book, leading experts provide detailed descriptions of the exciting treatments that are expected to become part of the ophthalmologist?s arsenal within the next 10?20 years. The treatments discussed relate to a wide variety of conditions, including macular degeneration, Leber?s congenital amaurosis, retinitis pigmentosa and choroideremia. The authors explain clearly how different gene and cell therapies work and provide first-hand accounts of the difficulties that they have faced in bringing these technologies to clinical trial, such as issues relating to funding and ownership. Results achieved to date are presented, and the further steps required before the treatment in question can become a routine option are considered. Gene- and Cell-Based Treatment Strategies for the Eye is unique in showing the organic development of cutting-edge science into potential treatments for eye disease without compromising on accurate reporting of scientific facts. It will persuade the average practitioner or researcher ? whether ophthalmologist, health worker, or scientist ? that change is indeed coming and is not just a hollow promise of the tabloid media.

    Contents:
    Introduction
    Gene Therapy for Leber?s Congenital Amaurosis due to RPE65 Mutations
    Gene Therapy for Choroideremia
    Gene Therapy for Dominantly Inherited Retinal Degeneration
    Age-Related Macular Degeneration: The Challenges
    Neovascular Age Related Macular Degeneration: Secretion Gene Therapy
    Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium for the Treatment of Macular Degeneration
    Restoring Physiologic Barriers Against Neovascular Invasion.
    Digital Access Springer 2015
  • Digital
    Punam Malik, John Tisdale, editors.
    Contents:
    1. Clinical features of β-thalassemia and sickle cell disease
    2. Genetic basis and genetic modifiers of β-thalassemia and sickle cell disease
    3. Current standards of care and long term outcomes for thalassemia and sickle cell disease
    4. Allogeneic/matched related transplantation for β-thalassemia and sickle cell anemia
    5. Alternative donor/unrelated donor transplants for the β-thalassemia and sickle cell disease
    6. Gene addition strategies for β-thalassemia and sickle cell anemia
    7. Reactivation of fetal hemoglobin for treating β-thalassemia and sickle cell disease
    8. Genome editing for β-hemoglobinopathies
    9. Gene and cell therapy for β-thalassemia and sickle cell disease with induced pluripotent stem cells (iPSCs): the next frontier
    Index.
    Digital Access Springer 2017
  • Digital
    Giridhara R. Jayandharan, editor.
    Summary: Recent advances in stem cell biology, nanotechnology and gene therapy have opened new avenues for therapeutics. The availability of molecular therapeutics that rely on the delivery of DNA, RNA or proteins, harnessing enhanced delivery with nanoparticles, and the regenerative potential of stem cells (adult, embryonic or induced pluripotent stem cells) has had a tremendous impact on translational medicine. The chapters in this book cover a range of strategies for molecular and cellular therapies for human disease, their advantages, and central challenges to their widespread application. Potential solutions to these issues are also discussed in detail. Further, the book addresses numerous advances in the field of molecular therapeutics that will be of interest to the general scientific community. Lastly, the book provides specific examples of disease conditions for which these strategies have been transferred to the clinic. As such, it will be extremely useful for all students, researchers and clinicians working in the field of translational medicine and molecular therapeutics.

    Contents:
    Part I: Gene Therapy
    Part II: Cell Therapy - "With emphasis on gene modified cell therapies."
    Digital Access Springer 2018
  • Digital
    Armin Ghobadi, John F. DiPersio, editors.
    Summary: Clinical and preclinical exploration of gene and cellular immunotherapy have seen rapid growth and interest with the development and approval of five Chimeric Antigen Receptor T-cell (CAR-T) products for lymphoma and myeloma and one Bispecific T-Cell Engager (BiTE) for acute lymphoblastic leukemia (ALL). These advances have dramatically improved the management of patients with relapsed refractory lymphoma, myeloma and leukemia. Gene and Cellular Immunotherapy for Cancer offers readers a comprehensive review of current cellular and gene-based immunotherapies. Divided into eighteen cohesive chapters, this book provides an in-depth and detailed look into cellular-based immunotherapies including CAR-T, TCR-T, TIL, Viral CTLs, NK cells in addition to T/NK cell engagers, focusing on their historical perspectives, biology, development and manufacturing, toxicities and more. Edited by two leading experts on gene and cellular immunotherapy, the book will feature chapters written by a diverse collection of recognized and up-and-coming experts and researchers in the field, providing oncologists, immunologists, researchers and clinical and basic science trainees with a bench to bedside view of the latest developments in the field.

    Contents:
    The History of Cellular Therapies
    Basics of Immunity
    Biology of CAR T cells
    Cell types used for CAR generation
    Combination therapeutics with CART cell therapy
    Safety switches used for cellular therapies
    Off-the-shelf CAR-T
    Manufacturing of CAR-T Cells: the Assembly Line
    Navigating Regulations in Gene and Cell Immunotherapy
    Bringing CAR-T to the Clinic
    CAR T-Cell Complications
    Mechanisms of Resistance and Relapse after CAR T cell therapy
    Tumor infiltrating lymphocytes (TIL): from bench to bedside
    T-cell Receptor (TCR) Engineered Cells and Their Transition to Clinic
    Viral Cytotoxic T Lymphocytes (CTLs): from Bench to Bedside
    Biology of NK cells and NK cells in clinic
    Biology and Clinical Evaluation of T/NK Cell Engagers
    Roadmap for Starting an Outpatient Cellular Therapy Program.
    Digital Access Springer 2022
  • Digital
    edited by Francesca Storici.
    Contents:
    RecTEPsy-mediated recombineering in Pseudomonas syringae / Bryan Swingle - Genome manipulations with bacterial recombineering and site-specific integration in Drosophila / Yi Zhang, William Schreiner, and Yikang S. Rong
    Multiple genetic manipulations of DT40 cell line / Akira Motegi and Minoru Takata
    Gene targeting of human pluripotent stem cells by homologous recombination / Sara E. Howden and James A. Thomson
    Methods for the assessment of ssODN-mediated gene correction frequencies in muscle cells / Carmen Bertoni
    Small fragment homologous replacement (SFHR) : sequence-specific modification of genomic DNA in eukaryotic cells by small DNA fragments/ Andrea Luchetti, Arianna Malgieri, and Federica Sangiuolo
    Preparation and application of triple helix forming oligonucleotides and single strand oligonucleotide donors for gene correction / Md. Rowshon Alam ... [et al.]
    Triplex-mediated genome targeting and editing / Faisal Reza and Peter M. Glazer
    Targeting piggyBac transposon integrations in the human genome / Daniel L. Galvan, Claudia S. Kettlun, and Matthew H. Wilson
    Gene targeting in human-induced pluripotent stem cells with adenoviral vectors / Kohnosuke Mitani
    Enhanced gene targeting of adult and pluripotent stem cells using evolved adeno-associated virus / Melissa A. Bartel and David V. Schaffer
    Lentiviral vectors encoding zinc-finger nucleases specific for the model target locus HPRT1 / Laetitia P.L. Pelascini and Manuel A.F.V. Gonçalves
    Designing and testing the activities of TAL effector nucleases / Yanni Lin, Thomas J. Cradick, and Gang Bao
    Bacterial one-hybrid system to isolate homing endonuclease variants with altered DNA target specificities / Rakesh Joshi and Frederick S. Gimble
    Design and analysis of site-specific single-strand nicking endonucleases for gene correction / Michael J. Metzger and Michael T. Certo
    CRISPR-Cas-mediated targeted genome editing in human cells / Luhan Yang ... [et al.]
    RNA-guided genome editing of mammalian cells / Neena K. Pyzocha ... [et al.]
    Nuclease-mediated double-strand break (DSB) enhancement of small fragment homologous recombination (SFHR) gene modification in human- induced pluripotent stem cells (hiPSCs) / R. Geoffrey Sargent, Shingo Suzuki, and Dieter C. Gruenert
    AAV-mediated gene editing via double-strand break repair / Matthew L. Hirsch and R. Jude Samulski
    Genetic modification stimulated by the induction of a site- specific break distant from the locus of correction in haploid and diploid yeast Saccharomyces cerevisiae / Samantha Stuckey and Francesca Storici
    Southern blot protocol to detect chimeric nuclease- mediated gene repair / Céline J. Rocca ... [et al.]
    High-throughput cellular screening of engineered nuclease activity using the single-strand annealing assay and luciferase reporter / Thomas J. Cradick, Christopher J. Antico, and Gang Bao
    Unbiased method for detection of genome-wide off- target effects in cell lines treated with zinc finger nucleases / Cory R. Lindsay and David B. Roth
    Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models / Eli J. Fine, Thomas J. Cradick, and Gang Bao
    Method for retinal gene repair in neonatal mouse / Marilyn Dernigoghossian ... [et al.]
    In utero delivery of oligodeoxynucleotides for gene correction / Lingzhi Cai ... [et al.]
    Portal vein delivery of viral vectors for gene therapy for hemophilia / Alexandra Sherman ... [et al.]
    Gene correction of induced pluripotent stem cells derived from a murine model of x-linked chronic granulomatous disorder / Sayandip Mukherjee and Adrian J. Thrasher
    Efficient transduction of hematopoietic stem cells and its potential for gene correction of hematopoietic diseases / Dolly Thomas and Gustavo Mostoslavsky.
    Digital Access Springer 2014
  • Digital
    edited by Xuenong Bo, Joost Verhaagen.
    Contents:
    Adeno-Associated Viral Vectors for Gene Delivery to the Nervous System
    Lentiviral Vectors for Gene Delivery to the Nervous System
    Gene Therapy for Parkinson's Disease: AAV-5-Mediated Delivery of Glial Cell Line-Derived Neurotrophic Factor (GDNF)
    Gene Delivery and Gene Therapy for Alzheimer's Disease
    Gene Therapy for Huntington's Disease
    Gene Therapy Approaches to Promoting Axonal Regeneration After Spinal Cord Injury
    Gene Delivery to Neurons of the Dorsal Root Ganglia Using Adeno-Associated Viral Vectors
    Targeted Gene Therapy for Ischemic Stroke
    Adeno-Associated Viral Gene Therapy for Retinal Disorders
    Gene Therapy for Epilepsies
    AAV Gene Therapy Strategies for Lysosomal Storage Disorders with Central Nervous System Involvement
    Gene Therapy in Spinal Muscular Atrophy (SMA) Models Using Intracerebroventricular Injection into Neonatal Mice
    Gene Therapy for Chronic Pain: How to Manipulate and Unravel Pain Control Circuits from the Brain?
    Gene Therapy Approaches Using Reproducible and Fully Penetrant Lentivirus-Mediated Endogenous Glioma Models
    Digital Access Springer 2015
  • Digital
    edited by Long Jason Lu.
    Contents:
    Microarray Transposon Tracking for the Mapping of Conditionally Essential Genes in Campylobacter jejuni
    Identifying Essential Streptococcus sanguinis Genes Using Genome-Wide Deletion Mutation
    Defining Essential Genes and Identifying Virulence Factors of Porphyromonas gingivalis by Massively-Parallel Sequencing of Transposon Libraries (Tn-seq)
    Identification of Essential Genes and Synthetic Lethal Gene Combinations in Escherichia coli K-12
    Identification of Genes Essential for Leptospirosis
    Identifying Essential Genes in Mycobacterium tuberculosis by Global Phenotypic Profiling
    Essential Genes in the Infection Model of Pseudomonas aeruginosa-PCR-Based Signature-Tagged Mutagenesis
    Genome-Wide Synthetic Genetic Screening by Transposon Mutagenesis in Candida albicans
    An Integrated Machine-Learning Model to Predict Prokaryotic Essential Genes
    A Statistical Framework for Improving Genomic Annotations of Transposon Mutagenesis (TM) Assigned Essential Genes
    A Proposed Essential Gene Discovery Pipeline: A Campylobacter jejuni Case Study
    Computational Prediction of Essential Metabolic Genes Using Constraint-Based Approaches
    Three Computational Tools for Predicting Bacterial Essential Genes
    Gene Essentiality Analysis Based on DEG 10, an Updated Database of Essential Genes
    Discovering Essential Domains in Essential Genes.
    Digital Access Springer 2015
  • Print
    Benjamin Lewin.
    Contents:
    --
    v. 2. Eucaryotic chromosomes.
    Print Access Request
    Location
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    Items
    Stored offsite. Please request print.
    QH450 .L481
    1
  • Digital
    edited by Michael F. Ochs, Department of Mathematics & Statistics, the College of New Jersey, Wing, NJ, USA.
    Contents:
    The Present State and Future Direction of Integrated Gene Function Analysis
    Performing Integrative Functional Genomics Analysis in GeneWeaver.org
    Functional Annotation of Differentially Regulated Gene Set Using WebGestalt: A Gene Set Predictive of Response to Ipilimumab in Tumor Biopsies
    Integrative Data-Mining Tools to Link Gene and Function
    Detection of Driver Protein Complexes in Breast Cancer Metastasis by Large-Scale Transcriptome-Interactome Integration
    Pattern Identification in Time-Course Gene Expression Data with the CoGAPS Matrix Factorization
    Statistical Tools and R Software for Cancer Driver Probabilities
    Predicting the Functional Consequences of Somatic Missense Mutations Found in Tumors
    Determining the Effect of DNA Methylation on Gene Expression in Cancer Cells
    Reverse Engineering Transcriptional Gene Networks
    Integrating In Silico Resources to Map a Signaling Network
    A Method for Inducible Gene Over-Expression and Down-Regulation in Emerging Model Species Using Pogostick
    Construction and Application of Site-Specific Artificial Nucleases for Targeted Gene Editing
    Selection of Recombinant Antibodies from Antibody Gene Libraries
    Construction of Simple and Efficient siRNA Validation Systems for Screening and Identification of Effective RNAi-Targeted Sequences from Mammalian Genes
    Rapid Genetic Modification of Mouse Embryonic Stem Cells by Inducible Cassette Exchange Recombination
    In Ovo Electroporation of miRNA-Based-Plasmids to Investigate Gene Function in the Developing Neural Tube
    Proteomic Strategies: SILAC and 2D-DIGE--Powerful Tool to Investigate Cellular Alterations
    Conditional Gene-Trap Mutagenesis in Zebrafish.
    Digital Access Springer 2014
  • Digital
    edited by Subhrangsu S. Mandal.
    Summary: The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, major emphasis is placed on pathological conditions, aiming at the many physiologists and developmental biologists who are familiar with the importance and mechanisms of hormone regulation but have a limited background in epigenetics.

    Contents:
    Eukaryotic Gene Expression by RNA Polymerase II / Geetha Durairaj, Shivani Malik, Sukesh R Bhaumik*
    Epigenetic Code / Arunoday Bhan, Paromita Deb, Subhrangsu S Mandal
    Histone Lysine Methylation, Demethylation, and Hormonal Gene Regulation / Yaling Huang, Briana Dennehey, Xiaobing Shi
    The Role of HATs and HDACs in Cell Physiology and Disease / Irene Santos-Barriopedro, Helena Raurell-Vila, Alejandro Vaquero
    The Short and Medium Stories of Noncoding RNAs: microRNA and siRNA / Arunoday Bhan, Paromita Deb, Milad Soleimani, Subhrangsu S Mandal
    Long Noncoding RNA (lncRNA): Functions in Health and Disease / Arunoday Bhan, Milad Soleimani, Subhrangsu S Mandal
    Histone Variants: Structure, Function, and Implication in Diseases / Francisca Alvarez, Alejandra Loyola
    Genomic Imprinting in Mammals: Origin and Complexity of an Epigenetically Regulated Phenomenon / Elena de la Casa-Esperón
    Centromere and Kinetochore: Essential Components for Chromosome Segregation / Shreyas Sridhar, Arti Dumbrepatil, Lakshmi Sreekumar, Sundar Ram Sankaranarayanan, Krishnendu Guin, Kaustuv Sanyal
    Nuclear Receptors and NR-coregulators: Mechanism of Action and Cell Signaling / Arunoday Bhan, Subhrangsu S Mandal
    Estrogen and Progesterone Receptor Signaling and Action / Linda I Perrotti
    Gonadal Steroid Hormones and Brain Protection / Meharvan Singh, Courtney Brock, Rebecca Cunningham, Chang Su
    Glucocorticoid Receptor-Mediated Signaling and Stress Metabolism / Rosalie M Uht, Shreyas A Bhave
    Targeting Androgen Signaling in Prostate Cancer / Paul H Chung, Preethi Ravindranathan, Bishoy A Gayed, Ganesh V Raj
    Role of Peroxisome Proliferator-Activated Receptors in Inflammation and Angiogenesis / Suchismita Acharya
    RAR/RXR-Mediated Signaling / Jörg Mey
    On the Trail of Thyroid Hormone Receptor Epigenetics / Pradip K Sarkar
    Insulin Signaling, Epigenetics, and Human Diseases / Ragitha Chruvattil, Muskaan Belani, Tushar P Patel, Sarita Gupta
    Endocrine Disruptors and Epigenetics / John D Bowman, Shaikh Mizanoor Rahman, Mahua Choudhury
    Endocrine Disruptors / Paromita Deb, Subhrangsu S Mandal.
    Digital Access Wiley v. 1-2=, 2017
  • Digital
    Shuji Terai, Takeshi Suda, editors.
    Summary: This book reports the recent progress in gene and cell therapy through the liver and aims to facilitate a comprehensive understanding of the current aspects and future prospects from basic research to clinical therapies. Edited by pioneering researchers, this volume presents extensive information to principal investigators, researchers, postdocs, and clinicians for examining the wide varieties of pathological conditions both inside and outside the liver. Providing not only the basic and clinical aspects of therapy, this volume is special in that it focuses on the administrative and regulatory difficulties of actual clinical application and legal regulations in different parts of the globe. By indicating the advantages and limitations of the most promising gene and cell therapies targeting the liver, this book will inspire readers to develop a feasible treatment in the next generation.

    Contents:
    1. Liver-Targeted Gene and Cell Therapies: An Overview
    Part I. Cell Therapy
    2. Macrophage Therapy for Liver Fibrosis and Regeneration
    3. Liver Regeneration Therapy Using Autologous Bone Marrow-Derived Cells for Cirrhotic Patients
    4. Novel Immunotherapy Using Liver Natural Killer Cells for Preventing Recurrence of Hepatocellular Carcinoma in Liver Transplantation
    5. Cell-Based Immunotherapy for HCC: Our Experiences and Future Directions
    Part II. Gene Therapy
    6. AAV Vector-Mediated Liver Gene Therapy and Its Implementation for Hemophilia
    7. Potential Usage of Human Artificial Chromosome for Regenerative Medicine
    8. Image-Guided Hydrodynamic Gene Delivery to the Liver: Toward Clinical Applications
    Part III. Legal Regulation 9. The Way to Clinical Applications of Human Pluripotent Stem Cells
    10. Regulation for Gene and Cell Therapy Medicinal Products in Europe
    11. IPSC-Derived Products: Current Regulations.- 12. Critical Path Initiative for Regenerative Medicine in Japan
    13. Aseptic Manufacturing of Regenerative Medicine Products Using Isolator Technology
    14. Cell and Vector Production Facility for Gene Therapy and Cell Therapy.
    Digital Access Springer 2016
  • Digital/Print
    Ben Berkhout, Hildegund C.J. Ertl, Marc S. Weinberg, editors.
    Contents:
    Gene therapies for hepatitis C virus / Monique M.A. Verstegen, Qiuwei Pan, and Luc J.W. van der Laan
    Recent advances in use of gene therapy to treat hepatitis B virus infection / Kristie Bloom, Abdullah Ely, and Patrick Arbuthnot
    U1interference (U1i) for antiviral approaches / Lorea Blázquez and Puri Fortes
    Gene therapy strategies to block HIV-1 replication by RNA interference / Elena Herrera-Carrillo and Ben Berkhout
    HIV and ribozymes / Robert J. Scarborough and Anne Gatignol
    Editing CCR5: a novel approach to HIV gene therapy / Tatjana I. Cornu, Claudio Mussolino, Kristie Bloom, and Toni Cathomen
    Synthetic DNA approach to cytomegalovirus vaccine/immune therapy / Stephan J. Wu, Daniel O. Villarreal, Devon J. Shedlock, and David B. Weiner
    Vector-mediated antibody gene transfer for infectious diseases / Bruce C. Schnepp and Philip R. Johnson
    HIV latency and the non-coding RNA therapeutic landscape / Sheena Saayman, Thomas C. Roberts, Kevin V. Morris, and Marc S. Weinberg
    C peptides as entry inhibitors for gene therapy / Lisa Egerer, Hans-Peter Kiem, and Dorothee von Laer
    Aptamer-siRNA chimeras for HIV / Mayumi Takahashi, John C. Burnett, and John J. Rossi
    Index.
    Digital Access Springer 2015
  • Digital
    Patrick Arbuthnot, Wits and South African Medical Research Council, Antiviral Gene Therapy Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, South Africa.
    Contents:
    Essentials of viruses and their suitability for treatment ssing gene therapy
    Harnessing RNAi to silence viral gene expression
    Engineering sequence-specific DNA binding proteins for antiviral gene editing
    Viral vectors for delivery of antiviral sequences
    Delivery of antiviral nucleic acids with nonviral vectors
    Gene therapy for chronic hepatitis B virus infection
    Gene therapy for hepatitis C virus infection
    Gene therapy for HIV-1 infection
    Gene therapy for respiratory viral infections
    Gene therapy for infection with hemorrhagic fever viruses
    Gene transfer for prophylaxis and therapy of viral infections
    Antiviral gene therapy : summary and perspectives.
    Digital Access ScienceDirect 2015
  • Digital
    edited by Mingjie Li and B. Joy Snider.
    Summary: Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system.
    Digital Access ScienceDirect 2018
  • Digital
    Giorgio Giatsidis, editor.
    Summary: This book offers an updated overview of the most recent research advances in the field, a comparison of established techniques and methods, a discussion on current experimental and translational challenges, and a commentary on potential opportunities and future directions. Dedicated chapters address and review the preclinical and clinical state-of-the-art of gene therapies for the reconstructive and regenerative surgery of skin and wounds, pathological scars, cartilage, tendons, skeletal muscles, and bio-engineered flaps. A brief guide to developing gene therapy clinical trials in the context of reconstructive and regenerative surgery is also provided. Biomedical and technological innovations are transforming our capacity to use gene therapies to safely and effectively repair, reconstruct, and regenerate tissues that are deficient or have been damaged by trauma and diseases. The targeted and controlled modulation of gene expression in tissues represents a game-changing, next-generation therapeutic tool for the modern reconstructive surgeon, expanding the horizon of regenerative surgery and tissue engineering. Through gene therapies, surgeons can direct (stem) cell differentiation and cell function, modulate the release of growth/transcriptional factors, affect the biological properties of regenerative scaffolds, control tissue inflammation, or induce immune-suppression in composite tissue allotransplants and xenotransplants. Written by renowned reconstructive surgeons and leading experts in each of these fields - from top academic institutions around the globe, the book provides an initial practical guide for veteran and newcomer surgeons alike, as well as for researchers interested in exploring the latest gene-based therapeutic strategies for reconstructive and regenerative surgery.

    Contents:
    Principles of gene therapy in reconstructive and regenerative surgery
    Gene therapy in skin and wound healing
    Gene therapy in pathologic scars
    Gene therapy in skeletal muscle repair and regeneration
    Gene therapy in cartilage repair and regeneration
    Gene therapy in tendon repair and regeneration
    Gene therapy and free flaps for therapeutic reconstructive surgery-- Developing a gene therapy clinical trial : tips and tricks
    Future directions in reconstructive and regenerative surgery.
    Digital Access Springer 2018
  • Digital
    edited by Wolfgang Walther and Ulrike Stein.
    Contents:
    Aptamer targeting the ERBB2 receptor tyrosine kinase for applications in tumor therapy / Georg Mahlknecht, Michael Sela, and Yosef Yarden
    Gene gun her2/neu DNA vaccination : evaluation of vaccine efficacy in a syngeneic her2/neu mouse tumor model / Tam Nguyen-Hoai, Antonio Pezzutto, and Jörg Westermann
    MIDGE technology for the production of a fourfold gene-modified, allogenic cell-based vaccine for cancer therapy / Manuel Schmidt, Barbara Volz, Patrick Grossmann, Kerstin Heinrich, and Burghardt Wittig
    Evaluation of bystander cell killing effects in suicide gene therapy of cancer : engineered thymidylate kinase (TMPK)/AZT enzyme-prodrug axis / Takeya Sato, Anton Neschadim, Ryo Nakagawa, Teruyuki Yanagisawa, and Jeffrey A. Medin
    Oncoleaking : use of the pore-forming Clostridium perfringens enterotoxin (CPE) for suicide gene therapy / Jessica Pahle, Jutta Aumann, Dennis Kobelt, and Wolfgang Walther
    iCaspase 9 suicide gene system / Xiaoou Zhou, Antonio Di Stasi, and Malcolm K. Brenner
    p53-encoding pDNA purification by affinity chromatography for cancer therapy / Ângela Sousa, João A. Queiroz, and Fani Sousa
    Phase 2, open-label, randomized study of pexa-vec (JX-594) administered by intratumoral injection in patients with unresectable primary hepatocellular carcinoma / Caroline J. Breitbach, Anne Moon, James Burke, Tae-Ho Hwang, and David H. Kirn
    Antiangiogenic metargidin peptide (AMEP) tene therapy in disseminated melanoma / Iben Spanggaard and Julie Gehl
    Clinical evaluation of ErbB-targeted CAR T-cells, rollowing intracavity delivery in patients with ErbB-expressing solid tumors / Sophie Papa, May van Schalkwyk, and John Maher.
    Digital Access Springer 2015
  • Digital
    edited by Joseph Ledoux.
    Contents:

    v. 1. Production and in vivo applications of gene transfer vectors. Preparation and quantification of pseudotyped retroviral vector / Hong Yu and Young Jik Kwon. Production of retroviral vectors for clinical use / Kenneth Cornetta, Lilith Reeves, and Scott Cross. Methods for the production of helper-dependent adenoviral vectors / Donna J. Palmer and Philip Ng. Methods for the production of first generation adenoviral vectors / Donna J. Palmer and Philip Ng. Large-scale production of recombinant adeno-associated viral vectors / Alejandro Negrete and Robert M. Kotin. Construction and production of recombinant herpes simplex virus vectors / William F. Goins ... [et al.] Plasmid-based gene transfer in mouse skeletal muscle by electroporation / Jonathan D. Schertzer and Goron S. Lynch. Chitosan nanoparticle-mediated gene transfer / Dongwon Lee and Shyam S. Mohapatra. PEG-PEI copolymers for oligonucleotide delivery to cells and tissues / Gordon J. Lutz, Shashank R. Sirsi, and Jason H. Williams. Non-viral gene delivery with cationic liposome-DNA complexes / Kai K. Ewert ... [et al.] Applications of lentiviral vectors in noninvasive molecular imaging / Abhijit De ... [et al.] Retroviral modification of mesenchymal stem cells for gene therapy of hemophilia A / Christopher B. Doering. Transduction of murine hematopoietic stem cells and in vivo selection of gene-modified cells / Lucienne M. Ide, Elisabeth Javazon, and H. Trent Spencer. Assessment of CFTR function after gene transfer in vitro and in vivo / Uta Griesenbach ... [et al.] Oncolytic adenoviruses for cancer gene therapy / Ta-Chiang Liu, Stephen H. Thorne, and David H. Kirn. Design of trans-splicing adeno-associated viral vectors for Duchenne muscular dystrophy gene therapy / Yi Lai ... [et al.] Prevention of type 1 diabetes in NOD mice by genetic engineering of hematopoietic stem cells / Jessamyn Bagley, Charoui Tian, and John Iacomini. Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells / Mingjie Li and John J. Rossi. Nanoparticle-mediated gene delivery to the lung / Rajagopal Ramesh. Retroviral-mediated gene therapy for the differentiation of primary cells into a mineralizing osteoblastic phenotype / Jennifer E. Phillips and Andrés J. García. In vivo siRNA delivery to the mouse hypothalamus shows a role of the co-chaperone XAP2 in regulating TRH transcription / Stéphanie Decherf, Zahra Hassani, and Barbara A. Demeneix. Efficient retroviral gene transfer to epidermal stem cells / Pedro Lei and Stelios T. Andreadis.
    Digital Access Springer v. 1-, 2008-
  • Digital
    Myles W. Jackson.
    Summary: In The Genealogy of a Gene, Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied "genealogy" of CCR5 -- intellectual property, natural selection, Big and Small Pharma, human diversity studies, personalized medicine, ancestry studies, and race and genomics -- Jackson links a myriad of diverse topics. The history of CCR5 from the 1990s to the present offers a vivid illustration of how intellectual property law has changed the conduct and content of scientific knowledge, and the social, political, and ethical implications of such a transformation. The CCR5 gene began as a small sequence of DNA, became a patented product of a corporation, and then, when it was found to be an AIDS virus co-receptor with a key role in the immune system, it became part of the biomedical research world -- and a potential moneymaker for the pharmaceutical industry. When it was further discovered that a mutation of the gene found in certain populations conferred near-immunity to the AIDS virus, questions about race and genetics arose. Jackson describes these developments in the context of larger issues, including the rise of "biocapitalism," the patentability of products of nature, the difference between U.S. and European patenting approaches, and the relevance of race and ethnicity to medical research.

    Contents:
    The story of the CCR5 gene
    The CCR5 patent(s)
    Gene patenting and the product-of-nature doctrine
    The CCR5 patent and intellectual property law
    The European response to the CCR5 patent
    CCR5 and HIV/AIDS diagnostics and therapeutics
    Race, place, and pathogens
    Race, difference, and genes
    Epilogue: the end of an error?
    Digital Access 2015
  • Digital/Print
    Panayiotis Vlamos, Athanasios Alexiou, editors.
    Summary: The 1st World Congress on Geriatrics and Neurodegenerative Disease Research (GeNeDis 2014) focused on recent advances in geriatrics and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments providing an international forum for the latest scientific discoveries, medical practices and care initiatives. This volume focuses on the bioinformatics and computational biology-related sessions

    Contents:
    1. Optoacoustics as a Bioengineering Model for Neuroscience Discovery / Vasilis Ntziachristos
    2. Respiratory Particle Deposition Probability Due to Sedimentation with Variable Gravity and Electrostatic Forces / Ioannis Haranas, Ioannis Gkigkitzis, George D. Zouganelis, Maria K. Haranas, and Samantha Kirk
    3. Sequence Patterns Mediating Functions of Disordered Proteins / Konstantinos P. Exarchos, Konstantina Kourou, Themis P. Exarchos, Costas Papaloukas, Michalis V. Karamouzis, and Dimitrios I. Fotiadis
    4. Management and Modeling of Balance Disorders Using Decision Support Systems: The EMBALANCE Project / Themis P. Exarchos, Christos Bellos, Iliana Bakola, Dimitris Kikidis, Athanasios Bibas, Dimitrios Koutsouris, and Dimitrios I. Fotiadis
    5. A Computer-Aided Diagnosis System for Geriatrics Assessment and Frailty Evaluation / Charalampos Vairaktarakis, Vasilis Tsiamis, Georgia Soursou, Filippos Lekkas, Markella Nikolopoulou, Emmanouilia Vasileiadou, Konstantinos Premtsis, and Athanasios Alexiou
    6. Exploiting Expert Systems in Cardiology: A Comparative Study / George-Peter K. Economou, Efrosini Sourla, Konstantina-Maria Stamatopoulou, Vasileios Syrimpeis, Spyros Sioutas, Athanasios Tsakalidis, and Giannis Tzimas
    7. Modeling Protein Misfolding in Charcot-Marie-Tooth Disease / Georgia Theocharopoulou and Panayiotis Vlamos
    8. The Effect of the Shape and Size of Gold Seeds Irradiated with Ultrasound on the Bio-Heat Transfer in Tissue / Ioannis Gkigkitzis, Carlos Austerlitz, Ioannis Haranas, and Diana Campos
    9. Clinical Decision Support System for the Diagnosis of Adolescence Health / Irene Moutsouri, Amalia Nikou, Machi Pampalou, Maria Lentza, Paulos Spyridakis, Natassa Mathiopoulou, Dimitris Konsoulas, Marianna Lampou, and Athanasios Alexiou
    10. Mitochondrial Fusion Through Membrane Automata / Konstantinos Giannakis and Theodore Andronikos
    11. A Mathematical Model for the Blood Plasma Flow Around Two Aggregated Low-Density Lipoproteins / Maria Hadjinicolaou
    12. Translation of Two Aggregated Low-Density Lipoproteins Within Blood Plasma: A Mathematical Model / Maria Hadjinicolaou and Eleftherios Protopapas
    13. Chaotic Attractors in Tumor Growth and Decay: A Differential Equation Model / Michael Harney and Wen-sau Yim
    14. Modeling k-Noncrossing Closed RNA Secondary Structures via Meandric Compression / Antonios Panayotopoulos and Panayiotis Vlamos
    15. Exploring the Online Satisfaction Gap of Medical Doctors: An Expectation-Confirmation Investigation of Information Needs / Panos E. Kourouthanassis, Patrick Mikalef, Margarita Ioannidou, and Adamantia Pateli
    16. A Cloud-Based Data Network Approach for Translational Cancer Research / Wei Xing, Dimitrios Tsoumakos, and Moustafa Ghanem.
    Digital Access Springer 2015
  • Digital/Print
    Panayiotis Vlamos, Athanasios Alexiou, editors.
    Summary: The 1st World Congress on Geriatrics and Neurodegenerative Disease Research (GeNeDis 2014), will focus on recent advances in geriatrics and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments and will provide an international forum for the latest scientific discoveries, medical practices and care initiatives. Advances information technologies will be discussed along with their implications for various research, implementation and policy concerns. In addition, the conference will address European and global issues in the funding of long-term care and medico-social policies regarding elderly people. GeNeDis 2014 takes place in Corfu, Greece, 10-13 April 2014. This volume focuses on the sessions that address geriatrics.

    Contents:
    Geriatrics
    Neurodegenerative Diseases
    Geriatric Psychiatry
    Mechanisms of Aging
    Metabolic Aging
    Cognititon and Aging
    Immunity and Aging
    End-of-Life Care
    Aging and Enviornmental Interaction.
    Digital Access Springer 2015
  • Digital/Print
    Panayiotis Vlamos, Athanasios Alexiou, editors.
    Summary: The 1st World Congress on Geriatrics and Neurodegenerative Disease Research (GeNeDis 2014) focused on recent advances in geriatrics and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments providing an international forum for the latest scientific discoveries, medical practices and care initiatives. Advanced information technologies were discussed along with their implications for various research, implementation and policy concerns. This volume focuses on neurodegenerative disease sessions.

    Contents:
    Neurodegenerative Diseases
    Brain Disorders
    Preclinical and Clinical Studies
    Diagnostic Protocols and Tests
    Drug Discoveries
    Neuropharmacology
    Neuroimaging.
    Digital Access Springer 2015
  • Digital
    Panayiotis Vlamos, editor.
    Summary: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people.

    Contents:
    Sis and Validation of Publications in Bioinformatics ation of new technologies in the production of pharmaceutical olive oil
    A survey of evolutionary games in biology
    DTCo: An ensemble SSL algorithm for X-rays classification
    Cognitive Enhancement and Brain-Computer Interfaces. Potential Boundaries and Risks
    Informatics and cognitive assessment: a RUDAS scale paradigm
    Effective stochastic algorithm in disease prediction
    A Systems Biology Approach for the Identification of Active Molecular Pathways during the Progression of Alzheimers Disease
    A brief survey of the Prisoners' Dilemma game and its potential use in biology
    Validation of modeling and simulation methods in computational biology
    An improved self-labeled algorithm for cancer prediction
    eHealth application for e-bloodanalysis, e-diagnosis and digital diet guidance
    Modeling the critical activation of chaperone machinery in protein folding
    ANTISOMA: A computational pipeline for the reduction of the aggregation propensity of monoclonal antibodies
    A microscale mathematical blood flow model for understanding cardiovascular diseases
    Blockchain For Mobile Health Applications Acceleration With GPU Computing
    Finite Size Effects in Networks of Coupled Neurons
    Detecting common pathways and key molecules of Neurodegenerative Diseases from the topology of molecular networks
    Robotic Systems involved in the diagnosis of Neurodegenerative diseases
    Undergraduate Students Brain Activity in Visual and Textual Programming
    Fuzzy logic Systems and Medical Applications
    Apache Spark Implementations for String Patterns in DNA Sequences
    Big Data Analysis and Genetic Liability to Neuropsychiatric Disease
    Mathematical models and computer simulation of chemical carninogenesis process and its inhibition by antocarcinogenic substances
    Transitioning knowledge levels through problem-solving methods
    Cellular phone users age or the duration of calls moderate autonomic nervous system? A meta-analysis
    Logical Analy.
    Digital Access Springer 2020
  • Digital
    Panayiotis Vlamos, editor.
    Summary: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people.

    Contents:
    In Silico and In Vivo Studies on Quercetin as Potential Anti- Parkinson Agent
    Exhaled Breath Condensate (EBC). Is it a viable source of biomarkers for lung diseases?
    Treatment development for Alzheimer's disease: how are we doing?
    Microbiome hijacking towards an integrative pest management pipeline
    Regulation and roles of autophagy in the brain
    Three-dimensional models for studying neurodegenerative and neurodevelopmental diseases
    Assessment of factors contributing to the enhancement of memory and cognitive abilities in the context of neurosciences
    Buccal Mucosa Biomarkers in Alzheimers Disease
    Engaging social interest and creating awareness for the behavioural and psychological symptoms of dementia
    Structural study of the DNA
    Clock/Bmal1 complex provides insights for the role of cortisol, hGR and HPA axis in stress management and sleep disorders
    The Effects of Quantum Entanglement on Chromatin and Gene Expression
    Olive Oil Polyphenols in Neurodegenerative Pathologies
    Human pluripotent stem cells as in vitro models of neurodegenerative diseases
    Nutritional Lipidomics in Alzheimer's Disease
    Alzeheimers Disease Therapeutic Approaches
    Stress and Wellbeing of Psychiatry Trainees: A Literature Review
    Brief Cognitive Tests in the case of Dementia and Alzheimers Disease Early Diagnosis
    Synthesis, Molecular Docking studies and Biological Evaluation of N-Acylarylhydrazones as Anti-inflammatory agents
    Exosome biomarkers revolutionize preclinical diagnosis of neurodegenerative diseases and assessment of treatment responses in clinical trials
    Biomarkers as a different approach in prevention and treatment of drug addiction (preliminary study)
    Sleep disorders and Restless Leg Syndrome in hemodialysis patients in Greece: a cross-sectional study
    Craniofacial and neurological phenotype in a patient with de novo 18q microdeletion and 18p microduplication
    What do recent clinical trials teach us about the et iology of AD
    Developmental Biology and Transgenic Avian Embryology: Body Alterity Bioart Wet Lab
    Gene editing, sexual reproduction and the arts: the present, the future and the imagined
    Amyotrophic Lateral Sclerosis: Current status in diagnostic biomarkers
    Synthesis and Characterization of Biologically Significant, 5-[N,N-dialkylamino alkoxy] azaindole 2-one,3- thiosemicarbazones and 5-[N,N-dialkylamino alkoxy] azaindole 3-hydrazone, 2-ones
    Genetic counseling for adult-onset spinal and bulbar muscular atrophy (Kennedy syndrome). Multiple cases of prenatal testing in a family
    Transcriptomics and Metabolomics in Amyotrophic Lateral Sclerosis
    Ocimum Sanctum Linn: A Potential Adjunct Therapy for Hyperhomocysteinemia
    Induced Vascular Dementia
    Alzheimer's disease: The role of mutations in protein folding.
    Digital Access Springer 2020
  • Digital
    Panayiotis Vlamos, editor.
    Summary: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people.

    Contents:
    A hypothesis of circulated microRnas implication in high incidence of atrial fibrillation and other electrocardiographic abnormalities in cancer patients
    Central Line-associated Bloodstream Infections (CLABSI) Incidence and the role of obesity: a prospective, observational study in Greece
    Number of brain states in an N-body dynamical scenario according to the universal Bekenstein entropy bound
    Burden and sleeping disorders of family caregivers of Hemodialysis patients with Chronic Kidney Disease-End Stage. A cross-sectional study
    Quality of life in type 2 diabetes mellitus patients with neuropsychological deficits
    A framework for assessing the impact of information seeking behavior on cancer patients long-term prognosis
    Sleeping Disorders and Health Related Quality of Life in Hemodialysis patients with Chronic Renal Disease in Greece
    Subjective Quality of Life, Religiousness and Spiritual Experience in Greek Orthodox Christians: Data from Healthy Aging and Patients with Cardiovascular Disease
    Mini-Mental State Examination: Greek normative data stratified by age and education in a large sample of 925 community-dwelling healthy participants
    The role of the family in the care of Alzheimer patients
    Prevalence of Stroke Cases in Warangal, Telangana Region, India: A Hospital-Based Case Study
    Compliance of Patients with Acute Coronary Syndrome with treatment following their hospitalization from the Cardiac Coronary Unit
    Using a Virtual Reality Serious Game to Assess the Performance of Older Adults with Frailty
    Characteristics and survival rates in ward patients requiring evaluation by Intensivist in Greece.
    Digital Access Springer 2020
  • Digital
    Panayiotis Vlamos, editor.
    Summary: The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. Computational methodologies for implementation on the discovery of biomarkers for neurodegenerative diseases are extensively discussed. This volume focuses on the sessions from the conference regarding computational biology and bioinformatics.
    Digital Access Springer 2021
  • Digital
    Panayiotis Vlamos, editor.
    Summary: The 4th World Congress on Genetics, Geriatrics, and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The relation between genetics and its effect on several diseases are thoroughly examined in this volume. This volume focuses on the sessions from the conference on Genetics and Neurodegenerative Diseases.
    Digital Access Springer 2021
  • Digital
    Panayiotis Vlamos, editor.
    Summary: The 4th World Congress on Genetics, Geriatrics and Neurodegenerative Diseases Research (GeNeDis 2020) focuses on the latest major challenges in scientific research, new drug targets, the development of novel biomarkers, new imaging techniques, novel protocols for early diagnosis of neurodegenerative diseases, and several other scientific advances, with the aim of better, safer, and healthier aging. The increase in the average length of life leads to the development of various diseases in the elderly population. This volume focuses on the sessions from the conference on Geriatrics.
    Digital Access Springer 2021
  • Digital
    Mark Greenwood, John G. Meechan.
    Summary: Aimed at the practising clinician, this book, now in its third edition, provides a welcome detailed overview of the medical and surgical conditions that affect patients seen in everyday dental practice. With patients surviving longer due to medical advances, dentists are increasingly faced with complex conditions and possibly some that they have not previously encountered. Here, treatment advice, drug interactions, and the impact of general medical and surgical conditions on treatment planning in the dental context are all covered with a comprehensive but practical approach. In addition to chapters on the implications for dental practice of disorders of each of the different body systems and immunological and infectious diseases, important aspects in particular patient groups, including cancer patients, the elderly, and the paediatric population, are identified. Overall, this book provides dentists with a practical, logical, and convenient guide of great value, helping to update knowledge and foster improved patient care.

    Contents:
    History and Examination in the Clothed Patient in the Dental Surgery
    The Cardiovascular System and Dental Practice
    The Respiratory System and Dental Practice
    The Gastrointestinal System and Dental Practice
    Neurological Disorders and Dental Practice
    Liver Disease and Dental Practice
    The Endocrine System and Dental Practice
    Renal Disorders and Dental Practice
    The Musculoskeletal System and Dental Practice
    Haematology and Patients with Bleeding Problems and Dental Practice
    Metabolic Disorders and Dental Practice
    Skin Disorders and Dental Practice
    Psychiatry and Dental Practice
    Cancer, Radiotherapy and Chemotherapy and Dental Practice
    The Paediatric Patient and Dental Practice
    The Older Patient and Dental Practice
    Medical Emergencies in Dentistry
    Infections and Infection Control in Dental Practice
    Immunology and the Dental Practitioner.
    Digital Access Springer 2018
  • Digital/Print
    Asbury, Taylor; Augsburger, James J.; Cunningham, Emmett T.; Riordan-Eva, Paul; Vaughan, Daniel; Whitcher, John.
    Digital Access
    Provider
    Version
    AccessMedicine
    AccessMedicine
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RE46 .V366
    4
  • Digital
    Nikolaos K. Paschos, George Bentley, editors.
    Summary: This volume of the Orthopaedic Study Guide Series provides the foundation of general orthopedic and basic science. Chapters of this book cohere around three aspects of the musculoskeletal system, anatomy, physiology, and pathology. Next to basic principles, case reports underline key information relating to disorders, diagnosis, and treatment options. Written by leading experts, this volume is a concise guide designed as quick reference, thereby it presents a useful resource for orthopedic residents and fellows. .
    Digital Access Springer 2019
  • Digital
    editors, K. Mohan Iyer and Wasim S. Khan.
    Summary: The second edition of this book concisely covers the most recent developments in orthopedics and trauma. It features detailed descriptions, x rays, clinical and therapeutic pathway diagrams for a number of commonly encountered disorders including fractures, metabolic disorders, bone tumors, and amputations enabling the reader to develop a deep understanding of the latest information on how to successfully diagnose and treat these patients. General Principles of Orthopedics and Trauma is an ideal resource for trainees and junior surgeons seeking an easy to follow clinical guide on how to successfully diagnose and treat patients with orthopedic and trauma disorders. It is also of use to the experienced practitioner seeking a practically applicable text on the latest advances in the field.
    Digital Access Springer 2019
  • Digital
    Lotte Hartmann-Kottek.
    Summary: This book highlights common similarities between the various schools of psychotherapy. It provides psychotherapists with the underlying neurophysiological, developmental psychological and relationship-oriented matrix (basic needs and their regulation, deficits, trauma and conflict processing patterns, including accompanying exercises) as well as opportunities for healing correction and stabilisation - and the ways in which to apply these methods in a therapeutically mindful way for the benefit of the patient. The new university-based psychotherapy training covers the four fundamental schools of psychotherapy, i.e. the previous standard approaches plus the systemic and humanistic ones. Focusing on the common ground builds bridges of understanding and encourages collaboration. This expanded, new range of methods to access patients constitutes a substantial development in the field of psychotherapy and will also influence the psychotherapy practice of experienced colleagues. Written for medical and psychological psychotherapists, psychosomatic doctors, psychiatrists and other specialists with additional psychotherapeutic qualifications, and for students of psychotherapy. .

    Contents:
    Intro
    Preface
    Contents
    Acknowledgements
    General Psychotherapy
    1: Psychotherapy Between Tradition and Awakening and Between Multiplicity and Integrity
    1.1 Psychotherapy as Science During a Period of Upheaval and the Search for Common Ground
    1.1.1 What Is Psychotherapy and Where Does It Belong as a Field?
    1.1.2 The Multiplicity of Our Psychotherapeutic Approaches - Confusion or Abundance?
    1.1.3 The Risk: When Research Turns into the Plaything of Competing Associations
    1.1.4 Are There Any Interdisciplinary Common Factors? 1.2 "Objectivity" - The Uncontroversial Main Feature of "Scientific Character"
    1.2.1 The Belief in Reason - A Gift from the Enlightenment
    1.2.2 The Drawback of Bias
    1.2.3 The Temptation to Define "Science" Using Currently Available Measurement Tools
    1.3 The "Necessary" Rediscovery of Subjectivity and Its Stake with Regard to Healing Therapy
    1.3.1 The Lack of Emotion Creates a New Abundance
    1.3.2 In Praise of Setting Limits: Crisis Intervention for Traumatic Inundation
    1.3.3 The Birth of Resource Perception, Encounters and Searching for Meaning 1.3.4 The Acceptance of Creativity, Physical Comfort and Role Play
    1.3.5 Simultaneous Fascination and Anti-establishment Sentiment: The Humanist Wave Hits Germany
    1.3.6 The Convincing Triumph of Empathy and Its Social Commitment
    1.4 The Discovery of the Abundance of Interspaces and Interpersonal Multi-person Structures
    1.4.1 The Apparent "Gaps" in Relationships
    1.4.2 The Pioneering Spirit of the First Generation of Couple, Family Therapy and Organisational Counsellors 1.5 The Unconscious - A Treasure Trove or an Unpredictable Sphinx? Discoveries in the Depths and Distance of Consciousness
    1.5.1 The Multifaceted Nature of the Unconscious
    1.5.2 Historical Milestones
    1.5.3 Hypnosis, Trance and Hypnotherapy
    1.6 "Artificial Intelligence" and the Complexity of Natural Brain Activity
    1.7 Mindfulness - The Borderline Impact of Transcendental Spaces
    1.7.1 Historical Waves of Encounters Between the "West" and the "Far East"
    1.7.2 Current Interest in "Mindfulness-Based" Therapy Approaches
    1.8 The "New Science of Psychotherapy" 1.8.1 Diversity with Common Reference Sciences
    1.8.2 General Development Trends
    1.8.3 Abandoned Aspects of Therapy
    1.8.4 The Zeitgeist in Upheaval
    1.8.5 Opportunities for Synopsis
    Literature
    2: Efficacies and Common Factors
    2.1 Mindful Awareness: As an Organ of Perception and as a Creative Force
    2.1.1 Two Consciousness-Modifying Forms of Being from One Basic Substance: The Focusing-Separating "Materialising-Locating" Pole - and the Interconnected-Oscillating, Non-local, Potentially Information-Receiving Pole with Floating Mixed States of Di
    Digital Access Springer 2022
  • Print
    editors, Shelby Reiter, Danielle Hayes.
    Summary: "Each year, general surgery residents across the county spend hundreds of hours studying for the American Board of Surgery certifying exam, also known as general surgery oral boards. This test is the final obstacle for general surgery residents on their journey to become board certified, practicing general surgeons in an easy to reference study guide with information covering the most commonly tested topics. This book is compiled based on ACS curriculum outlie making it helpful for medical students interested in surgery, general surgery residents, and practicing general surgeons. For each disease process, we include the relevant points of the history and physical, work-up, staging, treatment options, key surgical steps, and post-operative care. The unique format we use makes this book optimal for quick referencing and self-study. While this book was initially designed as a tool to study for the oral boards, it will also be extremely useful for residents and practicing surgeons as a quick reference guide in daily practice to brush up on procedural steps or the work up of complex conditions"-- Provided by publisher.
    Digital Access AccessSurgery c2024
  • Digital
    [edited by] Robert Lim, Daniel B. Jones.
    Contents:
    Sleep apnea / Ashley Willoughby
    Malignant hypertension / Harry Aubin
    FUSE : fire during temporal artery biopsy / Paul Wetstein
    Argon gas embolism / Roger Eduardo
    FLS : aortic trocar perforation / Megan Bowen
    Advanced laparascopy notes / Mark A. Gromski and Kai Matthes
    Robotic-assisted surgery / Brenda Schmidt and Gordon Wisbach
    Single incision and troubleshooting robotic surgery / Shah and Kudsi
    Ethical/legal issues, decision making / Steve Alcazar and Shawn Tsuda
    End of life care / Lam and Tsuda
    Skin cancer / Jigesh A. Shah and Omar Yusef Kudsi
    Decubitus ulcers / Pamela C. Masella and Mark K. Markarian
    Melanoma / Amber E. Ritenour
    Sarcoma and lymphoma / Joshua S. Ritenour
    Thoracic surgery, lung cancer, cough / Ashraf A. Sabe
    Abdominal wall reconstruction / Terri L. Carlson
    Hernia, umbilical/ventral with cirrhosis / Richard M. Peterson
    Asymptomatic inguinal hernia / Anez-Bustillos
    Femoral hernia / Harry T. Aubin
    Postoperative inguinal pain / Harry Aubin and Eric Balent
    Inguinal neuralgia / Aubin and Balent.
    Digital Access AccessSurgery 2017
  • Digital
    Brendon J. Coventry, editor.
    Summary: Written by internationally acclaimed specialists, General Surgery Risk Reduction expands on complications associated with surgery and how to reduce them, the availability of relevant information and the rapid advancements of surgical technology. Chapters provide pertinent and concise procedure descriptions creating a book that is both comprehensive and accessible. Stages of operative approaches with relevant technical considerations are outlined in an easily understandable manner. Complications are reviewed when appropriate for the organ system and problem. The text is illustrated throughout by line drawings and photographs that depict anatomic or technical principles. Forming part of the series, Surgery: Complications, Risks and Consequences, this volume General Surgery Risk Reduction provides a valuable resource for all general surgeons and residents in training. Other healthcare providers will also find this a useful resource.

    Contents:
    1. Introduction
    2. General Peri-operative Complications
    3. Surgical Infection
    4. Pre-Operative Risk Assessment and Intra-Operative Monitoring
    5. Anaesthesia Complications
    6. Intensive Care Complications
    7. Acute Peri-Operative Pain: Mechanisms and Management
    8. Systems, Safety and Quality : Harm, Error and Litigation
    9. Risk Management and Human Factors
    10. Medico-Legal Risk Management in Surgery
    11. Evaluation of Surgical Safety and Efficacy
    12. Accreditation, Credentialing, Scope of Practice and Outcome Evaluation.
    Digital Access Springer 2014
  • Digital
    Hans-Jörg Oestern, Otmar Trentz, Selman Uranues, editors.
    Summary: All European countries, including those that have recently joined the European Union or are candidates for membership, currently show a clear trend towards an increasing number of accidental injuries. This holds true for a range of injuries, including accidents among the elderly, sports injuries, and trauma due to traffic accidents. The increase in the number of injuries is accompanied by rising expectations among patients, who anticipate good functional results even after serious injuries. Despite these developments, trauma surgery is not yet established as an independent field in all European countries. Against this background, there is a clear need for a book that covers the state of the art in trauma surgery. This volume, which focuses on basics in trauma surgery is intended to help to meet this need. It will also serve to harmonize the practice of trauma surgery within the European Union and to prepare for the UEMS EBSQ trauma surgery.

    Contents:
    Trauma Care Systems
    Prehospital Trauma Care
    Trauma Scores
    Response to Major Incidents and Disasters: An Important Part of Trauma Management
    Polytrauma: Pathophysiology, Priorities, and Management
    Anesthesia and Pain Relief in Trauma Patients
    Contemporary Intensive Care Treatment for Patients with Severe Multiple Trauma
    Systemic Infections and Sepsis
    Necrotizing Soft-Tissue Infections
    Soft-Tissue Trauma
    Compartment Syndrome
    Plastic Surgery in Trauma
    Burn Injury
    Thromboembolism
    Muscle Injuries
    Tendon Injuries
    Treatment Principles of Nonunion
    Osteitis
    Pathologic Fractures.
    Digital Access Springer 2014
  • Print
    Kaplan, Jerry.
    Summary: Generative Artificial Intelligence: What Everyone Needs to Know ? equips readers with the knowledge to answer pressing questions about the impact of generative artificial intelligence on every facet of society.

    Contents:
    Cover
    Generative Artificial Intelligence
    Copyright
    Dedication
    Contents
    Acknowledgments
    Introduction
    1 The History of Artificial Intelligence
    What is Artificial Intelligence?
    Where did the term "Artificial Intelligence" originate?
    What were the Dartmouth conference participants hoping to accomplish?
    How did early AI researchers approach the problem?
    What is the "physical symbol system hypothesis"?
    What is Machine Learning?
    How did Machine Learning arise?
    What are some notable historical milestones in AI?
    2 Generative Artificial Intelligence (GAI) What are Large Language Models (LLMs)?
    How do Large Language Models work?
    What are "embeddings"?
    How do word embeddings represent meaning?
    What are Artificial Neural Networks?
    What is a Transformer?
    How do Transformers use word embeddings to express complex ideas?
    What are "tokens"?
    How are LLMs applied to non-​linguistic problems?
    What are "emergent properties" and do LLMs exhibit them?
    What is "jailbreaking" and why is it a difficult problem?
    What is "hallucination" and why do LLMs have them?
    What other techniques are used for GAI? How will future GAIs communicate with each other?
    What are some potential future proficiencies of GAIs?
    3 Likely Impact
    What historical precedents are benchmarks for the impact of GAI?
    How will GAI change healthcare?
    How will GAI change the legal system?
    How will GAI change education?
    How will GAI change software engineering?
    How will GAI change creative arts and industries?
    4 Future of Work
    Will GAI increase unemployment?
    How does automation affect labor markets?
    Which jobs are likely to fade away?
    Which jobs will not be affected? Which jobs will thrive and grow?
    What new industries and professions are likely to arise?
    What is "technological unemployment"?
    5 Risks and Dangers
    How will GAI be used to promote disinformation and propaganda?
    What is "algorithmic bias"?
    Will people turn from humans to machines for emotional support?
    How will GAIs impact the way we communicate?
    What is the "alignment problem"?
    Are "killer robots" just around the corner?
    Should we be concerned about "superintelligence" and the "singularity"?
    6 The Legal Status of GAIs Can a computer program enter into agreements and contracts?
    Should people bear full responsibility for their intelligent agents' actions?
    Should a GAI be granted legal rights, such as to own property?
    Can a GAI commit a crime?
    How can a GAI be held accountable for criminal acts?
    Why can't we just program GAIs to obey the law and other rules?
    7 Regulation, Public Policy, Global Competition
    Are GAIs protected by free-​speech laws?
    Can the output of a GAI be copyrighted?
    What regulatory schemes are being considered? What new laws and regulations are appropriate for GAIs?
    8 Philosophical Issues and Implications
    What is philosophy of Artificial Intelligence?
    Can a computer think?
    Can a computer be creative?
    Can a computer have free will?
    Can a computer be conscious?
    Can a computer feel?
    9 Outroduction
    Notes
    Index
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    Q334.7 K37 2024
    1
  • Print
    Jeremy A. Greene.
    Summary: Generic drugs are now familiar objects in clinics, drugstores, and households around the world. We like to think of these tablets, capsules, patches, and ointments as interchangeable with their brand-name counterparts: why pay more for the same? And yet they are not quite the same. They differ in price, in place of origin, in color, shape, and size, in the dyes, binders, fillers, and coatings used, and in a host of other ways. Claims of generic equivalence, as physician-historian Jeremy Greene reveals, are never based on being identical to the original drug in all respects, but in being the same in all ways that matter. How do we know what parts of a pill really matter? Decisions about which differences are significant and which are trivial in the world of therapeutics are not resolved by simple chemical or biological assays alone. Questions of therapeutic similarity and difference are also always questions of pharmacology and physiology, of economics and politics, of morality and belief. Greene chronicles the social, political, and cultural history of generic drugs, narrating the evolution of the generic drug industry from a set of mid-twentieth-century "schlock houses" and "counterfeiters" into an agile and surprisingly powerful set of multinational corporations in the early twenty-first century. The substitution of bioequivalent generic drugs for more expensive brand-name products is a rare success story in a field of failed attempts to deliver equivalent value in health care for a lower price. Greene's history sheds light on the controversies shadowing the success of generics: problems with the generalizability of medical knowledge, the fragile role of science in public policy, and the increasing role of industry, marketing, and consumer logics in late-twentieth-century and early twenty-first century health care.

    Contents:
    Introduction: The same but not the same
    What's in a name?
    No such thing as a generic drug?
    The sciences of similarity
    Laws of substitution
    Paradoxes of generic consumption
    The generic alternative.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Books: General Collection (Downstairs)
    RM301 .G74 2014
    1
  • Print
    Donald O. Beers.
    Print Access Request
    Location
    Version
    Call Number
    Items
    Retired Reference (Downstairs)
    KF3894.G45 B44
    1
  • Digital
    edited by Sabrina Tosi, Alistair Reid.
    Contents:
    Molecular genetics of the myeloproliferative neoplasms / Philip A Beer
    Acute myeloid leukaemia / Dr Matthew L. Smith & Dr Thomas McKerrell
    Molecular genetics of pediatric acute myeloid leukemia (AML) / M.M. van den Heuvel-Eibrink, J.D.E. de Rooij, and C.M. Zwaan
    Acute lymphoblastic leukemia / Anna Andersson, Anthony V. Moorman, Christine J. Harrison and Charles Mullighan
    The genetics of mature b-cell malignancies / Jonathan C. Strefford, Jude Fitzgibbon, Matthew J.J. Rose-Zerilli and Csaba Bödör
    The genetics of chronic myelogenous leukaemia / Philippa C. May, Jamshid S. Khorashad, Mary Alikian, Danilo Perrotti and Alistair G. Reid.
    Digital Access Wiley 2016
  • Digital
    Alexandre Rezende Vieira.
    Summary: This book explains the genetic basis of a wide range of dental disorders, including dental caries, periodontitis, congenital anomalies, malocclusions, orofacial pain, dental implant failure, and cancer. Such conditions are typically multifactorial or complex, with involvement of more than one gene as well as environmental influences. A sound grasp of this framework is ever more important, given the emergence of consumer genomics, including direct-to-consumer genetic testing. Dental professionals now need to understand why one person is susceptible to a particular oral health condition while a first-degree relative either does not develop the condition or does so in a less severe form. Knowledge of how genes operate in the susceptible host is essential if patients are to be offered accurate advice about their risks. The information provided in this book will assist in the delivery of effective personalized dental care through optimization of preventive strategies. It will enable the practitioner to explain the extent to which a patients condition is pure "bad luck", whether that bad luck can be changed by behavioral choices, and how many of our behaviors are influenced by genes.

    Contents:
    Complex Inheritance in Oral Health Conditions
    Genetic Basis of Enamel and Dentin Defects
    Genetic Basis of Tooth Agenesis, Supernumerary Teeth, and Other Dental Abnormalities
    Genetic Basis of Dental Caries and Periapical Pathology
    Genetic Basis of Periodontitis and Tooth Loss
    Genetic Basis of Dental Implant Failure and Alveolar Ridge Resorption
    Genetic Basis of Craniofacial Deformities and Malocclusion, Oral Clefts, and Craniosynostosis
    Genetic Basis of Lichen Planus and Oral Cancer
    Genetic Basis of Orofacial Pain and Temporomandibular Joint Dysfunction
    Genetic Influence on Behavior and the Impact on Oral Health Conditions.
    Digital Access Springer 2019
  • Digital
    Jeanette Erdmann, Alessandra Moretti, editors.
    Summary: This book provides a comprehensive summary of the latest developments in the field of the genomics of cardiac disease. Written and edited by leading clinicians and scientists involved in the analysis and therapy of genetic cardiac disorders, it discusses the genetic causes of a variety of cardiac diseases, such as the complex genetics and etiology of congenital heart diseases. It also explores sex differences in prevalent diseases, genetics-based therapeutic strategies and the use of various animal models and alternatives. The book is intended for research scientists and clinical scientists in the cardiovascular field, human geneticists and cardiologists.

    Contents:
    Genetics of adult and fetal forms of Long QT Syndrome
    The genetic landscape of cardiomyopathies. Genetic basis of mitochondrial cardiomyopathy
    The Genetics of Coronary Heart Disease
    Complex genetics and the etiology of human congenital heart disease-Familial Hypercholesterolemia
    Long non-codingRNAs in cardiovascular disease
    Mouse models to study inherited cardiomyopathy
    Interrogating cardiovascular genetics in zebrafish
    Human induced pluripotent stem cells as a platform for functional examination of cardiovascular genetics in a dish
    Systems medicine as a transforming tool for cardiovascular genetics
    Sex differences in prevalent cardiovascular disease in the general population.
    Digital Access Springer 2019
  • Print
    edited by Laura Hercher, Sarah Lawrence College, Barbara Biesecker, RTI International, Jehannine C. Austin, University of British Columbia.
    Summary: "Genetic counseling is poised to play an increasingly important role in society as genome sequencing becomes a routine aspect of clinical assessment of both infants and adults. This volume examines the changing role of genetic counselors in the genomic age and the ways in which genetic counseling can be integrated into modern medicine"-- Provided by publisher.
    Print
    Location
    Version
    Call Number
    Items
  • Digital
    Jill S. Goldman, editor.
    Summary: Will I end up just like my parent? Will the children get it too? Why is this happening to me? The adult patient diagnosed with or at risk for a neurogenetic disease has many questions and concerns for the genetic counselor, the neurologist, and other practitioners. Because of the emotional and potentially life-altering impact of these diseases on the patient and family, counseling can be especially challenging. A rare hands-on guide to the subject, Genetic Counseling for Adult Neurogenetic Disease deals with core issues that differentiate adult neurogenetic counseling from its more familiar pediatric counterpart. This innovative book with accompanying videos is designed to fill in deficits in this area typical of training programs in genetic counseling (which have pediatrics and prenatal concentrations) and neurology (which rarely cover genetic counseling). For each condition featured, chapters include a detailed overview of genetic symptoms, diagnostic criteria, and management, plus guidelines for asking, and answering, pertinent questions. The major concentration, however, is on genetic counseling issues and case histories illustrating these issues. As an added dimension, the accompanying videos depict representative issues and challenges in genetic counseling for specific diseases in addition to the basics of a neurological examination. Among the conditions discussed: Movement disorders, including Parkinson's disease. Dementias, including Alzheimer's disease. Stroke. Motor neuron diseases. Neuropathies and channelopathies. Adult muscular dystrophies. Neurocutaneous syndromes. Plus a section on neurological and neuropsychological evaluation. This is information that will stay relevant as technologies change and genetic understanding evolves. Genetic Counseling for Adult Neurogenetic Disease offers advanced clinical wisdom for genetic counselors as well as neurologists, neuropsychologists, and other referring clinicians.

    Contents:
    Part 1:The Movement Disorders
    1. Overview
    2. Huntington Disease
    3. Parkinson Disease
    4. Dystonia
    5. Ataxia
    Part 2:The Dementias
    6. Overview
    7. Alzheimer?s Disease
    8. Frontotemporal Degeneration
    9. Prion Diseases
    Part 3:Stroke
    10. Overview of Cerebrovascular Disease and Stroke Risk Factors
    11. CADASIL
    Part 4:The Motor Neuron Diseases
    12. Overview
    13. Amyotrophic Lateral Sclerosis
    14. Spinal Bulbar Muscular Atrophy: Kennedy?s Disease
    15. Hereditary Spastic Paraplegia
    Part 5:The Neuropathies and Channelopathies
    16. Charcot Marie Tooth
    17. Channelopathies
    18. Overview
    19. The Myopathies
    20. The Muscular Dystrophies
    21. The Myotonic Dystrophies
    Part 7:Neurocutaneous Syndromes
    22. Overview
    23. Neurofibromatosis
    24. Tuberous sclerosis
    Part 8:The Clinical Evaluation
    25. The Neurological Examination and Testing
    26. The Neuropsychological Evaluation.
    Digital Access Springer 2015
  • Digital
    edited by Bonnie S. LeRoy, Patricia McCarthy Veach, Nancy P. Callanan.
    Summary: "Rapid increases in tests and technologies, media attention, and the expansion of genetic medicine and testing beyond conditions that are exclusively genetic in nature to common chronic illnesses with both genetic and environmental components (e.g., diabetes, heart disease, cancer), have raised demand for genetic counselling services and changing the scope of practice. Genetic counselors help individuals and families understand complex medical information, including diagnosis, prognosis, management options, risk, and heredity issues. They aid patients in decision-making while respecting ethical, familial, and cultural standards"-- Provided by publisher.

    Contents:
    Introduction / Bonnie S. LeRoy, Patricia Mccarthy Veach, and Nancy P. Callanan
    Complicated shadows : the limitations of autonomy in genetic counseling / Robert G. Resta
    Actively engaging with patients in decision-making / Andrea Shugar and Cheryl Shuman
    Risk assessment and communication : a complex process / Shannan Delany Dixon, MaryAnn W. Campion, and Claire N. Singletary
    A genetic counselor's guide to understanding grief / Nadia Ali and Cecelia Bellcross
    Patient anger : insights and strategies / Lynn Schema
    Resistance and adherence : understanding the patient's perspective / Krista Redlinger-Grosse
    Countertransference : making the unconscious conscious / Krista Redlinger-Grosse
    Supporting family communication about genetic conditions / Marion Mcallister, Rhona Macleod, and Alison Metcalfe
    Developmentally-based approaches for counseling children and adolescents / Stephanie Austin and Kelly Schoch
    Cultural competency and genetic counseling : key concepts / Nancy Steinberg Warren
    Cultural competency : application to genetic counseling / Nancy Steinberg Warren
    Education in genetic counseling : the impacts of genetic literacy and adult learning / Andrea L. Durst and Rachel Mills
    Adapting genetic counseling practice to different models of service delivery / Angela Trepanier and Dawn C. Allain
    "Oh the places you'll go!" The genetic counselor professional development journey / Catherine A. Reiser
    Development of the genetic counseling profession : a professionalization process / Bonnie Jeanne Baty
    Digital Access Wiley 2021

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Derived from Current Medical Diagnosis & Treatment, AccessMedicine's Quick Medical Diagnosis & Treatment provides topic reviews with key diagnostic and treatment features for more than 500 diseases.

A repository of medical knowledge from internal medicine, cardiology, genetics, pharmacy, diagnosis and management, basic sciences, patient care, and more.

Continuously expanding, all databases in the repository contain the latest editions of selected medical titles.

MicroMedex: Premier pharmaceutical information source containing multiple databases and drug reference tools. Of particular value is DRUGDEX Evaluations, one of the most comprehensive drug sources available. DynaMed is a clinical information resource used to answer questions quickly at the point-of-care. Easy-to-interpret Levels of Evidence help clinicians rapidly determine the quality of the available evidence.

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Multidisciplinary coverage of over 10,000 high-impact journals in the sciences, social sciences, and arts and humanities, as well as international proceedings coverage for over 120,000 conferences.

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Cochrane reviews are created through a strict process of compiling and analyzing data from multiple randomized control trials to ensure comprehensiveness and reliability.

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Largest, broadest eBook package; covers all sciences, as well as technology (including software), medicine, and humanities.

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Large number of high quality software and database programming titles from O'Reilly. Other software titles are also available from Sams and Prentice Hall. Limited to 7 concurrent users. Includes peer-reviewed life science and biomedical research protocols compiled from Methods in Molecular Biology, Methods in Molecular Medicine, Methods in Biotechnology, Methods in Pharmacology and Toxicology, Neuromethods, the Biomethods Handbook, the Proteomics Handbook, and Springer Laboratory Manuals. Contains full text access to selected biomedical and nursing books.

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Collection of over 8 thousand fulltext titles in engineering, math, and basic and applied biomedical research. Coverage is from 1967 to the present. A library of ebooks on a wide array of topics, digitized and made available online in conjunction with the original publishers.